Identified secondary metabolite regions

ACJE01000021.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 4.1 NRPS 499,690 556,036 Nidulanin A polyketide 75%
Region 4.2 T1PKS,NRPS 881,716 933,859 Phyllostictine A / phyllostictine B nrps-t1pks 20%
Region 4.3 NRPS-like 1,147,344 1,187,218
Region 4.4 terpene 1,277,684 1,295,536
Region 4.5 terpene 1,454,373 1,472,621
Region 4.6 NRPS 2,733,888 2,792,907
Region 4.7 T3PKS 2,958,855 2,999,847
Region 4.8 terpene 3,090,657 3,112,870
ACJE01000020.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 5.1 T1PKS 93,800 135,392 Pyranonigrin E polyketide 100%
Region 5.2 T1PKS 557,415 605,387 Fusarielin H t1pks 50%
ACJE01000019.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 6.1 NRPS 37,417 86,307
Region 6.2 T1PKS 107,880 152,686 Pyranonigrin E polyketide 100%
Region 6.3 terpene 658,480 678,140 Shearinine D terpene 13%
Region 6.4 T1PKS 937,954 982,571
Region 6.5 T1PKS 1,006,332 1,046,887
Region 6.6 NRPS-like,T1PKS 1,103,893 1,155,937 Communesin polyketide 12%
Region 6.7 NRPS-like,T1PKS 1,403,391 1,463,108
Region 6.8 terpene 1,589,972 1,611,344
Region 6.9 NRPS,T1PKS 1,615,225 1,667,170 Wortmanamide A t1pks 100%
Region 6.10 T1PKS 2,370,151 2,417,541
ACJE01000018.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 7.1 T1PKS 1,066 36,100 Aflavarin t1pks 60%
Region 7.2 T1PKS 106,714 154,844
ACJE01000016.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 9.1 NRPS-like 273,724 315,723
Region 9.2 T1PKS,NRPS-like 1,090,748 1,147,266 HC-toxin NRPS 100%
Region 9.3 NRPS-like 1,338,997 1,376,737
Region 9.4 siderophore 1,387,840 1,399,604
Region 9.5 NRPS 1,560,687 1,607,665
ACJE01000015.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 10.1 NRPS 1,462 36,746
Region 10.2 T1PKS 55,518 93,097
Region 10.3 NRPS,terpene 165,730 206,887
Region 10.4 terpene 212,716 234,399 Aflatrem terpene 11%
Region 10.5 NRPS 708,165 768,628 Dimethylcoprogen NRPS 100%
Region 10.6 terpene 1,073,785 1,095,400 HC-toxin NRPS 100%
Region 10.7 T1PKS 1,131,876 1,177,799
Region 10.8 T1PKS 1,200,738 1,246,453 Duclauxin t1pks 50%
Region 10.9 NRPS-like 1,257,743 1,296,970
Region 10.10 NRPS 1,329,221 1,375,872
Region 10.11 T1PKS 1,421,768 1,469,918 Elsinochrome A t1pks 100%
ACJE01000014.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 11.1 NRPS 1 47,463
ACJE01000013.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 12.1 NRPS-like 111,725 154,820
ACJE01000012.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 13.1 T1PKS 13,804 59,143 Yanuthone D t1pks 100%
ACJE01000010.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 15.1 T1PKS 139,453 186,027
Region 15.2 NRPS-like 227,638 268,447
Region 15.3 NRPS 1,264,604 1,306,606
Region 15.4 NRPS,T1PKS 2,089,414 2,141,201 Wortmanamide A t1pks 100%
Region 15.5 T1PKS 2,421,821 2,469,643 Pyripyropene A terpene-t1pks 25%
Region 15.6 NRPS-like 2,604,456 2,647,242
Region 15.7 terpene 2,833,373 2,854,578
ACJE01000009.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 16.1 NRPS,T1PKS 1 45,681 Isoflavipucine nrps-t1pks 12%
Region 16.2 terpene 150,156 172,172
Region 16.3 indole 544,714 566,091
ACJE01000008.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 17.1 T1PKS 567,029 610,781
Region 17.2 T1PKS 981,655 1,025,015
Region 17.3 T1PKS 1,203,572 1,250,965
Region 17.4 NRPS 1,783,005 1,836,475
ACJE01000007.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 18.1 NRPS-like 46,895 84,943
Region 18.2 terpene 208,790 230,189
Region 18.3 NRPS-like 243,741 284,620
ACJE01000006.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 19.1 T1PKS 1,045,786 1,092,569
Region 19.2 NRPS 1,093,624 1,145,686
ACJE01000005.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 20.1 siderophore 160,157 171,528
Region 20.2 NRPS 238,023 290,983
Region 20.3 NRPS,T1PKS 465,403 571,546 T-toxin t1pks 100%
Region 20.4 T1PKS 655,196 702,955
Region 20.5 terpene 718,650 740,255
ACJE01000004.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 21.1 terpene 425,655 447,672
Region 21.2 T1PKS 594,272 640,699
Region 21.3 NRPS,T1PKS 1,728,749 1,812,152 Fumonisin t1pks 47%
Region 21.4 NRPS-like 2,893,383 2,936,971
Region 21.5 betalactone 3,265,572 3,294,682
Region 21.6 NRPS-like 3,680,765 3,724,529
ACJE01000003.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 22.1 indole 460,314 481,306
Region 22.2 T1PKS,NRPS-like 586,604 638,938 Notoamide NRPS 11%
Region 22.3 NRPS,T1PKS 682,321 752,972 Aureobasidin A1 NRPS 100%
ACJE01000002.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 23.1 NRPS,T1PKS 470,512 521,905 HC-toxin NRPS 100%
Region 23.2 terpene 527,440 548,657
Region 23.3 T1PKS,NRPS-like 1,157,902 1,203,466
ACJE01000001.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 24.1 NRPS 109,829 166,460 Aflatrem terpene 17%
Region 24.2 T1PKS 288,268 333,266
Region 24.3 NRPS,T1PKS 375,131 480,312 Azanigerone t1pks 100%
Region 24.4 terpene 588,981 607,418
Region 24.5 NRPS-like 1,155,547 1,198,396
Region 24.6 T1PKS 1,223,388 1,266,093
Region 24.7 T1PKS 1,321,446 1,368,125 Naphthopyrone t1pks 100%
Region 24.8 terpene 1,416,084 1,434,356
Region 24.9 terpene 1,515,938 1,539,480 Clavaric acid terpene 100%
No secondary metabolite regions were found in these records:
ACJE01000024.1 (Aspergillus niger)
ACJE01000023.1 (Aspergillus niger)
ACJE01000022.1 (Aspergillus niger)
ACJE01000017.1 (Aspergillus niger)
ACJE01000011.1 (Aspergillus niger)
Compact view
ACJE01000021.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 499,690 - 556,036 nt. (total: 56,347 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location <499689 - >556036:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - X - hydrophilic - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_52774: X - X - hydrophilic - X
Search NORINE for peptide: strict or relaxed

AMP-binding (254..652): X
NRPSPredictor2: phe, trp, phg, tyr, bht
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aromatic
Large clusters prediction:
phe, trp, phg, tyr, bht
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
daviiaavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1797..2197): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmqsvafssk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2839..3243): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvlstgavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3930..4331): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
damfvggifk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000021.1 - Region 2 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 881,716 - 933,859 nt. (total: 52,144 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 881715 - 933859:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk - gln)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_176722: pk - gln
Search NORINE for peptide: strict or relaxed

PKS_AT (550..868): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 76.3
Methoxymalonyl-CoA: 61.9
Ethylmalonyl-CoA: 55.9
Malonyl-CoA: 37.3
Isobutyryl-CoA: 34.7
Benzoyl-CoA: 28.7
Propionyl-CoA: 23.5
fatty_acid: 22.5
trans-1,2-CPDA: 20.4
Acetyl-CoA: 14.5
CHC-CoA: 12.1
3-Methylbutyryl-CoA: 10.1
inactive: 0.0
2-Methylbutyryl-CoA: -1.3

AMP-binding (2993..3402): gln
NRPSPredictor2: gln
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
glu, gln
Single AA prediction:
gln
Stachelhaus prediction details:
Stachelhaus sequence:
nhdkfgsisk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000021.1 - Region 3 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,147,344 - 1,187,218 nt. (total: 39,875 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location <1147343 - 1187218:
Polymer prediction:
(hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_38316: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (23..349): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
aayldcc--k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000021.1 - Region 4 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,277,684 - 1,295,536 nt. (total: 17,853 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000021.1 - Region 5 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,454,373 - 1,472,621 nt. (total: 18,249 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000021.1 - Region 6 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 2,733,888 - 2,792,907 nt. (total: 59,020 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 2733887 - 2792907:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (X - pro - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_47271: X
Search NORINE for peptide: strict or relaxed

AMP-binding (48..471): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
gllhiasptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_207636: X - pro - X
Search NORINE for peptide: strict or relaxed

AMP-binding (238..683): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dpamwitiak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1396..1805): pro
NRPSPredictor2: pro
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
pro
Stachelhaus prediction details:
Stachelhaus sequence:
dvqhtitvvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2521..2926): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dplstgaigk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000021.1 - Region 7 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 2,958,855 - 2,999,847 nt. (total: 40,993 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000021.1 - Region 8 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 3,090,657 - 3,112,870 nt. (total: 22,214 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000020.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 93,800 - 135,392 nt. (total: 41,593 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location <93799 - >135392:
Polymer prediction:
(redmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_187099: redmal
PKS_AT (573..889): redmal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 62.5%
inactive: 58.3%

minowa: Isobutyryl-CoA
Prediction, score:
Isobutyryl-CoA: 77.4
Methylmalonyl-CoA: 76.9
Methoxymalonyl-CoA: 69.4
Malonyl-CoA: 62.0
Ethylmalonyl-CoA: 41.3
Propionyl-CoA: 33.7
inactive: 30.4
3-Methylbutyryl-CoA: 29.7
2-Methylbutyryl-CoA: 27.8
Benzoyl-CoA: 24.2
trans-1,2-CPDA: 21.6
Acetyl-CoA: 13.8
CHC-CoA: 12.1
fatty_acid: 11.4


ACJE01000020.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 557,415 - 605,387 nt. (total: 47,973 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 557414 - 605387:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_211885: pk
PKS_AT (567..830): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 72.2
Methoxymalonyl-CoA: 61.0
Ethylmalonyl-CoA: 60.4
Propionyl-CoA: 35.5
fatty_acid: 24.9
Benzoyl-CoA: 23.7
trans-1,2-CPDA: 22.4
2-Methylbutyryl-CoA: 19.7
Isobutyryl-CoA: 12.8
3-Methylbutyryl-CoA: 12.4
Malonyl-CoA: 6.6
CHC-CoA: 6.6
inactive: 0.0
Acetyl-CoA: 0.0


ACJE01000019.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 37,417 - 86,307 nt. (total: 48,891 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location <37416 - >86307:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(hydrophobic-aliphatic - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_118659: hydrophobic-aliphatic - X
Search NORINE for peptide: strict or relaxed

AMP-binding (47..442): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
vmaivavgak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1128..1509): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dawfvg-lhk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000019.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 107,880 - 152,686 nt. (total: 44,807 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location <107879 - >152686:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_179585: pk
PKS_AT (566..879): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 62.5%
Isobutyryl-CoA: 54.2%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 88.5
Methoxymalonyl-CoA: 85.2
Isobutyryl-CoA: 79.1
Malonyl-CoA: 68.2
Ethylmalonyl-CoA: 47.5
Propionyl-CoA: 45.7
Benzoyl-CoA: 39.1
inactive: 38.5
3-Methylbutyryl-CoA: 30.4
trans-1,2-CPDA: 26.0
2-Methylbutyryl-CoA: 24.2
Acetyl-CoA: 23.4
CHC-CoA: 11.7
fatty_acid: 10.7


ACJE01000019.1 - Region 3 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 658,480 - 678,140 nt. (total: 19,661 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000019.1 - Region 4 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 937,954 - 982,571 nt. (total: 44,618 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location <937953 - >982571:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_138585: pk
PKS_AT (511..816): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 70.8
Methoxymalonyl-CoA: 65.2
Malonyl-CoA: 41.9
Isobutyryl-CoA: 35.6
Propionyl-CoA: 23.4
Benzoyl-CoA: 20.5
trans-1,2-CPDA: 19.5
3-Methylbutyryl-CoA: 19.5
fatty_acid: 15.9
inactive: 9.8
2-Methylbutyryl-CoA: 3.7
CHC-CoA: 0.0
Acetyl-CoA: 0.0
Ethylmalonyl-CoA: -3.2


ACJE01000019.1 - Region 5 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,006,332 - 1,046,887 nt. (total: 40,556 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location <1006331 - >1046887:
Polymer prediction:
(redmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_179079: redmal
PKS_AT (562..898): redmal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 70.8%
Ethylmalonyl-CoA: 62.5%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 92.7
Methylmalonyl-CoA: 80.4
Methoxymalonyl-CoA: 79.0
Isobutyryl-CoA: 60.1
Ethylmalonyl-CoA: 50.6
Propionyl-CoA: 39.6
Benzoyl-CoA: 24.1
3-Methylbutyryl-CoA: 23.3
inactive: 23.1
fatty_acid: 18.5
2-Methylbutyryl-CoA: 12.8
trans-1,2-CPDA: 8.8
CHC-CoA: 5.5
Acetyl-CoA: 0.0


ACJE01000019.1 - Region 6 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,103,893 - 1,155,937 nt. (total: 52,045 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 1103892 - 1155937:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 7, location 1103892 - >1144818:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 8, location 1110836 - 1155937:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_129526: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (15..338): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
------ifyk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_39026: pk
PKS_AT (460..736): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Methylmalonyl-CoA: 58.3%
Ethylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 66.1
Methoxymalonyl-CoA: 64.9
Isobutyryl-CoA: 45.2
Malonyl-CoA: 43.4
fatty_acid: 23.3
Propionyl-CoA: 23.2
Acetyl-CoA: 20.1
Benzoyl-CoA: 20.0
inactive: 15.2
3-Methylbutyryl-CoA: 13.6
trans-1,2-CPDA: 13.1
CHC-CoA: 8.8
Ethylmalonyl-CoA: -0.4
2-Methylbutyryl-CoA: -3.2


ACJE01000019.1 - Region 7 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,403,391 - 1,463,108 nt. (total: 59,718 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 9, location <1403390 - >1463108:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 10, location <1403390 - >1441213:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 11, location <1423039 - >1463108:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_39114: X
Search NORINE for peptide: strict or relaxed

AMP-binding (88..350): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
nhsymgh--k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_47991: pk
PKS_AT (507..811): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Methylmalonyl-CoA: 58.3%
Propionyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 66.2
Methoxymalonyl-CoA: 55.6
Propionyl-CoA: 51.2
2-Methylbutyryl-CoA: 26.7
CHC-CoA: 26.2
Benzoyl-CoA: 22.9
fatty_acid: 19.9
trans-1,2-CPDA: 17.2
Ethylmalonyl-CoA: 16.7
Malonyl-CoA: 10.1
Isobutyryl-CoA: 8.7
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


ACJE01000019.1 - Region 8 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,589,972 - 1,611,344 nt. (total: 21,373 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000019.1 - Region 9 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,615,225 - 1,667,170 nt. (total: 51,946 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 13, location 1615224 - 1667170:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk - leu)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_118644: pk - leu
Search NORINE for peptide: strict or relaxed

PKS_AT (546..862): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 62.5%
Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 57.2
Methoxymalonyl-CoA: 48.5
Malonyl-CoA: 26.6
Propionyl-CoA: 24.2
Benzoyl-CoA: 21.3
Ethylmalonyl-CoA: 20.9
Isobutyryl-CoA: 19.8
inactive: 18.3
fatty_acid: 13.8
trans-1,2-CPDA: 8.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

AMP-binding (2755..3157): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dafllgavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000019.1 - Region 10 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 2,370,151 - 2,417,541 nt. (total: 47,391 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 14, location 2370150 - 2417541:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_53054: X
Search NORINE for peptide: strict or relaxed

AMP-binding (30..432): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
gawfgsspvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_118629: pk
PKS_AT (552..853): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Methylmalonyl-CoA: 58.3%
Ethylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 83.9
Ethylmalonyl-CoA: 80.5
Methoxymalonyl-CoA: 74.6
Malonyl-CoA: 59.7
Isobutyryl-CoA: 48.4
Propionyl-CoA: 30.7
Benzoyl-CoA: 27.6
2-Methylbutyryl-CoA: 24.2
CHC-CoA: 22.7
fatty_acid: 17.3
trans-1,2-CPDA: 16.5
3-Methylbutyryl-CoA: 11.0
Acetyl-CoA: 2.5
inactive: 0.0


ACJE01000018.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,066 - 36,100 nt. (total: 35,035 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location <1065 - >36100:
Polymer prediction:
(mal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_51499: mal
PKS_AT (895..1194): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 71.5
inactive: 51.9
Methoxymalonyl-CoA: 45.1
Methylmalonyl-CoA: 40.2
2-Methylbutyryl-CoA: 19.3
Propionyl-CoA: 18.2
Isobutyryl-CoA: 14.2
Ethylmalonyl-CoA: 13.9
fatty_acid: 12.7
CHC-CoA: 12.4
trans-1,2-CPDA: 11.9
3-Methylbutyryl-CoA: 10.6
Benzoyl-CoA: 9.8
Acetyl-CoA: 0.0


ACJE01000018.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 106,714 - 154,844 nt. (total: 48,131 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 106713 - 154844:
Polymer prediction:
(redmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_118662: redmal
PKS_AT (491..849): redmal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 62.5%
inactive: 54.2%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 96.1
Methoxymalonyl-CoA: 77.9
Methylmalonyl-CoA: 76.0
Isobutyryl-CoA: 55.3
Ethylmalonyl-CoA: 49.9
inactive: 45.9
Propionyl-CoA: 36.7
Benzoyl-CoA: 29.8
2-Methylbutyryl-CoA: 20.4
fatty_acid: 18.3
Acetyl-CoA: 16.4
trans-1,2-CPDA: 15.8
3-Methylbutyryl-CoA: 10.0
CHC-CoA: 7.7


ACJE01000016.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 273,724 - 315,723 nt. (total: 42,000 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 273723 - >315723:
Polymer prediction:
(leu)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_190264: leu
Search NORINE for peptide: strict or relaxed

AMP-binding (6..406): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dlfflgttlk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000016.1 - Region 2 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,090,748 - 1,147,266 nt. (total: 56,519 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 1090747 - >1147266:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 1090747 - 1138191:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location <1108606 - >1147266:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk) + (X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_44006: X
Search NORINE for peptide: strict or relaxed

AMP-binding (17..443): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
fswygavvfk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_44005: pk
PKS_AT (547..861): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Methylmalonyl-CoA: 62.5%
Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 64.3
Methoxymalonyl-CoA: 58.3
Ethylmalonyl-CoA: 47.4
Isobutyryl-CoA: 37.7
Malonyl-CoA: 35.0
trans-1,2-CPDA: 25.0
Benzoyl-CoA: 24.6
fatty_acid: 16.8
CHC-CoA: 14.2
2-Methylbutyryl-CoA: 13.1
Propionyl-CoA: 8.7
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


ASPNIDRAFT_190891: X
Search NORINE for peptide: strict or relaxed

AMP-binding (7..412): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmcivggifk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000016.1 - Region 3 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,338,997 - 1,376,737 nt. (total: 37,741 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location <1338996 - >1376737:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_55018: X
Search NORINE for peptide: strict or relaxed

AMP-binding (268..736): X
NRPSPredictor2: asp, asn, glu, gln, aad
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dprhfvmrak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000016.1 - Region 4 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,387,840 - 1,399,604 nt. (total: 11,765 nt) Show pHMM detection rules used
siderophore: IucA_IucC

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000016.1 - Region 5 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,560,687 - 1,607,665 nt. (total: 46,979 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 7, location 1560686 - 1607665:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_118635: X - X
Search NORINE for peptide: strict or relaxed

AMP-binding (257..636): X
NRPSPredictor2: asp, asn, glu, gln, aad
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
sardvgsqlk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1280..1664): X
NRPSPredictor2: phe, trp
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
phe, trp
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dgfcagaick
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000015.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,462 - 36,746 nt. (total: 35,285 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location <1461 - >36746:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - X - X - X - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_55153: X - X - X - X - X
Search NORINE for peptide: strict or relaxed

AMP-binding (234..634): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dallfgavlk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1327..1735): X
NRPSPredictor2: gly, ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
gly, ala
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvgcvgivwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2422..2818): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvafvgsiwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3506..3905): X
NRPSPredictor2: gly, ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
gly, ala
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvgcvgiiwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (4593..4988): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvgcsgiiwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000015.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 55,518 - 93,097 nt. (total: 37,580 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location <55517 - >93097:
Polymer prediction:
(mal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_194381: mal
PKS_AT (925..1204): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 58.3%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 57.9
inactive: 36.3
Methylmalonyl-CoA: 33.4
Methoxymalonyl-CoA: 30.5
Ethylmalonyl-CoA: 18.1
fatty_acid: 15.3
Benzoyl-CoA: 12.6
CHC-CoA: 12.5
trans-1,2-CPDA: 11.2
Isobutyryl-CoA: 11.0
Propionyl-CoA: 9.8
2-Methylbutyryl-CoA: 9.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


ACJE01000015.1 - Region 3 - NRPS,terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 165,730 - 206,887 nt. (total: 41,158 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location <165729 - >206887:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(leu - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_128584: leu - X
Search NORINE for peptide: strict or relaxed

AMP-binding (26..422): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dalfigavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1144..1546): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
digsvamiyk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000015.1 - Region 4 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 212,716 - 234,399 nt. (total: 21,684 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000015.1 - Region 5 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 708,165 - 768,628 nt. (total: 60,464 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location <708164 - >768628:
Polymer prediction:
(hydrophilic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_191228: hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (164..568): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvdggggigk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000015.1 - Region 6 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,073,785 - 1,095,400 nt. (total: 21,616 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000015.1 - Region 7 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,131,876 - 1,177,799 nt. (total: 45,924 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 8, location 1131875 - >1177799:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_118598: pk
PKS_AT (537..750): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 66.7%
Methylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 47.2
Methoxymalonyl-CoA: 43.1
Malonyl-CoA: 41.4
Ethylmalonyl-CoA: 29.9
Isobutyryl-CoA: 24.9
fatty_acid: 21.1
inactive: 16.2
Benzoyl-CoA: 14.7
CHC-CoA: 13.7
trans-1,2-CPDA: 11.6
2-Methylbutyryl-CoA: 11.0
Propionyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


ACJE01000015.1 - Region 8 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,200,738 - 1,246,453 nt. (total: 45,716 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 9, location <1200737 - >1246453:
Polymer prediction:
(mal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_191422: mal
PKS_AT (907..1206): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 85.9
inactive: 42.8
Methoxymalonyl-CoA: 36.2
Methylmalonyl-CoA: 32.7
Isobutyryl-CoA: 24.7
CHC-CoA: 22.0
2-Methylbutyryl-CoA: 21.7
Propionyl-CoA: 18.2
Ethylmalonyl-CoA: 18.0
Acetyl-CoA: 16.2
Benzoyl-CoA: 15.0
fatty_acid: 13.7
3-Methylbutyryl-CoA: 11.1
trans-1,2-CPDA: 0.0


ACJE01000015.1 - Region 9 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,257,743 - 1,296,970 nt. (total: 39,228 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 10, location <1257742 - >1296970:
Polymer prediction:
(pro)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_191357: pro
Search NORINE for peptide: strict or relaxed

AMP-binding (4..406): pro
NRPSPredictor2: pro
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
pro, pip
Small clusters prediction:
pro
Single AA prediction:
pro
Stachelhaus prediction details:
Stachelhaus sequence:
dmfflativk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000015.1 - Region 10 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,329,221 - 1,375,872 nt. (total: 46,652 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 11, location 1329220 - 1375872:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(ala - hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_44571: ala - hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (48..447): ala
NRPSPredictor2: ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
gly, ala
Single AA prediction:
ala
Stachelhaus prediction details:
Stachelhaus sequence:
dasgllipyk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1119..1530): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dahnilapvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000015.1 - Region 11 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,421,768 - 1,469,918 nt. (total: 48,151 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 12, location 1421767 - 1469918:
Polymer prediction:
(redmmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_191702: redmmal
PKS_AT (572..876): redmmal
ATSignature: Malonyl-CoA, Methylmalonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 75.0%
Ethylmalonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 67.6
Methoxymalonyl-CoA: 61.2
Malonyl-CoA: 46.7
Isobutyryl-CoA: 35.4
Propionyl-CoA: 25.2
Ethylmalonyl-CoA: 21.9
2-Methylbutyryl-CoA: 12.9
3-Methylbutyryl-CoA: 10.2
CHC-CoA: 7.7
trans-1,2-CPDA: 6.3
Acetyl-CoA: 1.7
inactive: 0.0
fatty_acid: 0.0
Benzoyl-CoA: 0.0


ACJE01000014.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1 - 47,463 nt. (total: 47,463 nt) Show pHMM detection rules used
Region on contig edge.
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 0 - 47463:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - ala - hydrophobic-aliphatic - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_118601: X - ala - hydrophobic-aliphatic - X
Search NORINE for peptide: strict or relaxed

AMP-binding (35..430): X
NRPSPredictor2: orn, lys, arg
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
orn, lys, arg
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvsdvgpptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1505..1909): ala
NRPSPredictor2: ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
gly, ala
Single AA prediction:
ala
Stachelhaus prediction details:
Stachelhaus sequence:
dvcihiltfk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2594..2996): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvadtgsptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3676..4073): X
NRPSPredictor2: orn, lys, arg
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
orn, lys, arg
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvsdvgpptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000013.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 111,725 - 154,820 nt. (total: 43,096 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 111724 - 154820:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_183440: X
Search NORINE for peptide: strict or relaxed

AMP-binding (25..424): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dtvqiggvyk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000012.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 13,804 - 59,143 nt. (total: 45,340 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 13803 - 59143:
Polymer prediction:
(ccmmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_44965: ccmmal
PKS_AT (586..877): ccmmal
ATSignature: Methylmalonyl-CoA, Malonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 75.0%
Malonyl-CoA: 75.0%
Ethylmalonyl-CoA: 70.8%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 111.9
Ethylmalonyl-CoA: 94.8
Methoxymalonyl-CoA: 91.0
Isobutyryl-CoA: 67.1
Malonyl-CoA: 58.2
trans-1,2-CPDA: 46.4
Benzoyl-CoA: 44.0
Propionyl-CoA: 40.9
2-Methylbutyryl-CoA: 40.5
Acetyl-CoA: 31.8
fatty_acid: 30.0
CHC-CoA: 16.5
3-Methylbutyryl-CoA: 16.1
inactive: 10.4


ACJE01000010.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 139,453 - 186,027 nt. (total: 46,575 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location <139452 - >186027:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_118617: pk
PKS_AT (553..868): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
Methylmalonyl-CoA: 70.8%
Ethylmalonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 74.2
Methoxymalonyl-CoA: 64.2
Malonyl-CoA: 54.0
Isobutyryl-CoA: 46.5
Ethylmalonyl-CoA: 29.3
Propionyl-CoA: 27.0
2-Methylbutyryl-CoA: 12.9
fatty_acid: 12.2
Benzoyl-CoA: 10.7
trans-1,2-CPDA: 9.7
inactive: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


ACJE01000010.1 - Region 2 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 227,638 - 268,447 nt. (total: 40,810 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location <227637 - >268447:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_36645: X
Search NORINE for peptide: strict or relaxed

AMP-binding (70..353): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hlsq--t--k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000010.1 - Region 3 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,264,604 - 1,306,606 nt. (total: 42,003 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location <1264603 - >1306606:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_36929: X
Search NORINE for peptide: strict or relaxed

AMP-binding (223..615): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvlevgavvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000010.1 - Region 4 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 2,089,414 - 2,141,201 nt. (total: 51,788 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 2089413 - 2141201:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_118624: pk - X
Search NORINE for peptide: strict or relaxed

PKS_AT (571..886): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 66.7%
2-Methylbutyryl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 74.7
Methoxymalonyl-CoA: 63.7
Malonyl-CoA: 45.8
Isobutyryl-CoA: 40.4
Benzoyl-CoA: 34.8
Ethylmalonyl-CoA: 31.7
Propionyl-CoA: 25.9
3-Methylbutyryl-CoA: 19.9
fatty_acid: 15.8
Acetyl-CoA: 14.7
inactive: 14.0
trans-1,2-CPDA: 11.1
CHC-CoA: 9.3
2-Methylbutyryl-CoA: 7.2

AMP-binding (2769..3154): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
daftfvamak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000010.1 - Region 5 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 2,421,821 - 2,469,643 nt. (total: 47,823 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 2421820 - 2469643:
Polymer prediction:
(redmmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_37260: redmmal
PKS_AT (554..856): redmmal
ATSignature: Malonyl-CoA, Methylmalonyl-CoA
Top 3 matches:
Malonyl-CoA: 66.7%
Methylmalonyl-CoA: 66.7%
CE-Malonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 71.0
Methoxymalonyl-CoA: 67.0
Malonyl-CoA: 36.4
Propionyl-CoA: 34.7
Ethylmalonyl-CoA: 31.5
trans-1,2-CPDA: 31.1
fatty_acid: 25.3
2-Methylbutyryl-CoA: 21.4
CHC-CoA: 16.9
Isobutyryl-CoA: 15.8
Benzoyl-CoA: 15.6
Acetyl-CoA: 8.4
inactive: 0.0
3-Methylbutyryl-CoA: 0.0


ACJE01000010.1 - Region 6 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 2,604,456 - 2,647,242 nt. (total: 42,787 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 2604455 - 2647242:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_173610: X
Search NORINE for peptide: strict or relaxed

AMP-binding (25..443): X
NRPSPredictor2: glu, gln
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
glu, gln
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
vgefvggagk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000010.1 - Region 7 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 2,833,373 - 2,854,578 nt. (total: 21,206 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000009.1 - Region 1 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1 - 45,681 nt. (total: 45,681 nt) Show pHMM detection rules used
Region on contig edge.
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 0 - 45681:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk - leu)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_118581: pk - leu
Search NORINE for peptide: strict or relaxed

PKS_AT (568..884): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
Methylmalonyl-CoA: 66.7%
2-Methylbutyryl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 66.7
Methoxymalonyl-CoA: 59.4
Ethylmalonyl-CoA: 38.6
Propionyl-CoA: 31.7
Isobutyryl-CoA: 23.0
Benzoyl-CoA: 20.1
3-Methylbutyryl-CoA: 14.0
2-Methylbutyryl-CoA: 13.6
fatty_acid: 13.3
inactive: 11.2
Malonyl-CoA: 10.7
trans-1,2-CPDA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0

AMP-binding (2805..3214): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
daalmgavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_131416: X
Search NORINE for peptide: strict or relaxed

AMP-binding (9..471): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
gllyigcpik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000009.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 150,156 - 172,172 nt. (total: 22,017 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000009.1 - Region 3 - indole
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 544,714 - 566,091 nt. (total: 21,378 nt) Show pHMM detection rules used
indole: (indsynth or dmat or indole_PTase)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000008.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 567,029 - 610,781 nt. (total: 43,753 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location <567028 - >610781:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_181803: pk
PKS_AT (560..885): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
Methylmalonyl-CoA: 66.7%
2-Methylbutyryl-CoA: 58.3%

minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 75.8
Methylmalonyl-CoA: 68.4
Malonyl-CoA: 59.6
Isobutyryl-CoA: 43.3
Propionyl-CoA: 36.5
Ethylmalonyl-CoA: 31.9
inactive: 21.9
fatty_acid: 21.5
Benzoyl-CoA: 19.7
3-Methylbutyryl-CoA: 18.4
CHC-CoA: 17.5
trans-1,2-CPDA: 15.4
2-Methylbutyryl-CoA: 14.4
Acetyl-CoA: 0.0


ACJE01000008.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 981,655 - 1,025,015 nt. (total: 43,361 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location <981654 - >1025015:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_210217: pk
PKS_AT (568..888): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 62.5%
Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 66.3
Malonyl-CoA: 63.1
Methoxymalonyl-CoA: 54.1
Ethylmalonyl-CoA: 38.7
Isobutyryl-CoA: 28.5
2-Methylbutyryl-CoA: 18.7
Propionyl-CoA: 18.2
trans-1,2-CPDA: 17.4
inactive: 17.3
Benzoyl-CoA: 15.2
CHC-CoA: 15.1
fatty_acid: 7.5
Acetyl-CoA: 1.4
3-Methylbutyryl-CoA: 0.0


ACJE01000008.1 - Region 3 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,203,572 - 1,250,965 nt. (total: 47,394 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 1203571 - 1250965:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_118744: pk
PKS_AT (514..831): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 58.3%
Isobutyryl-CoA: 58.3%

minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 71.8
Methylmalonyl-CoA: 67.7
Malonyl-CoA: 38.7
Propionyl-CoA: 37.9
Isobutyryl-CoA: 37.9
Ethylmalonyl-CoA: 37.6
inactive: 25.6
2-Methylbutyryl-CoA: 20.8
fatty_acid: 10.1
trans-1,2-CPDA: 8.8
Benzoyl-CoA: 5.3
Acetyl-CoA: 1.7
CHC-CoA: 0.0
3-Methylbutyryl-CoA: -2.9


ACJE01000008.1 - Region 4 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,783,005 - 1,836,475 nt. (total: 53,471 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 1783004 - 1836475:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - hydrophobic-aliphatic - leu)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_182031: X - hydrophobic-aliphatic - leu
Search NORINE for peptide: strict or relaxed

AMP-binding (118..517): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dfiivgapik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1217..1615): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
davviaamvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2334..2729): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dailvgaqik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000007.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 46,895 - 84,943 nt. (total: 38,049 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 46894 - >84943:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_194895: X
Search NORINE for peptide: strict or relaxed

AMP-binding (20..423): X
NRPSPredictor2: phe, trp, phg, tyr, bht
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aromatic
Large clusters prediction:
phe, trp, phg, tyr, bht
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hmllygaiik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000007.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 208,790 - 230,189 nt. (total: 21,400 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000007.1 - Region 3 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 243,741 - 284,620 nt. (total: 40,880 nt) Show pHMM detection rules used
Region on contig edge.
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 243740 - 284620:
Polymer prediction:
(hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_195043: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (38..434): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hlvicgavik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000006.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,045,786 - 1,092,569 nt. (total: 46,784 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 1045785 - 1092569:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_118666: pk
PKS_AT (543..851): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 87.5%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 92.0
Methoxymalonyl-CoA: 89.2
Malonyl-CoA: 87.1
Isobutyryl-CoA: 75.0
Ethylmalonyl-CoA: 66.3
Benzoyl-CoA: 40.2
Propionyl-CoA: 35.2
2-Methylbutyryl-CoA: 30.9
trans-1,2-CPDA: 29.2
inactive: 28.8
Acetyl-CoA: 25.0
fatty_acid: 15.6
CHC-CoA: 13.5
3-Methylbutyryl-CoA: 10.6


ACJE01000006.1 - Region 2 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,093,624 - 1,145,686 nt. (total: 52,063 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 1093623 - 1145686:
Polymer prediction:
(hydrophobic-aliphatic - hydrophobic-aliphatic - hydrophilic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_42205: hydrophobic-aliphatic - hydrophobic-aliphatic - hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (516..922): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dianmgnfvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1598..1999): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dawlvgavik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3139..3550): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dagsvggiek
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000005.1 - Region 1 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 160,157 - 171,528 nt. (total: 11,372 nt) Show pHMM detection rules used
siderophore: IucA_IucC

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000005.1 - Region 2 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 238,023 - 290,983 nt. (total: 52,961 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location <238022 - >290983:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - pro - X - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_118599: X - pro - X - X
Search NORINE for peptide: strict or relaxed

AMP-binding (74..483): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvlfaggvak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1579..1977): pro
NRPSPredictor2: pro
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
pro, pip
Small clusters prediction:
pro
Single AA prediction:
pro
Stachelhaus prediction details:
Stachelhaus sequence:
dtqhfasvak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2672..3069): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvsfagsiwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3752..4148): X
NRPSPredictor2: gly, ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
gly, ala
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
digsvgiiyk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000005.1 - Region 3 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 465,403 - 571,546 nt. (total: 106,144 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 465402 - >571546:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(hydrophobic-aliphatic - hydrophobic-aliphatic - X - X) + (X) + (redmmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 465402 - 541957:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(hydrophobic-aliphatic - hydrophobic-aliphatic - X - X) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 5, location <529783 - >571546:
Polymer prediction:
(redmmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_43807: hydrophobic-aliphatic - hydrophobic-aliphatic - X - X
Search NORINE for peptide: strict or relaxed

AMP-binding (105..497): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmlicgfink
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1160..1550): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
daamaigimk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2334..2728): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
damfgglivk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3880..4277): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dawfvgailk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_43800: X
Search NORINE for peptide: strict or relaxed

AMP-binding (20..455): X
NRPSPredictor2: phe, trp
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
phe, trp
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
vlmvislfck
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_189378: redmmal
PKS_AT (548..847): redmmal
ATSignature: Methylmalonyl-CoA, Malonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 75.0%
Malonyl-CoA: 75.0%
Isobutyryl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 84.4
Malonyl-CoA: 69.9
Methoxymalonyl-CoA: 69.7
Isobutyryl-CoA: 60.6
Ethylmalonyl-CoA: 52.8
Benzoyl-CoA: 43.4
Propionyl-CoA: 37.8
fatty_acid: 21.1
trans-1,2-CPDA: 20.6
2-Methylbutyryl-CoA: 18.9
Acetyl-CoA: 15.2
CHC-CoA: 11.8
inactive: 10.6
3-Methylbutyryl-CoA: 0.0


ACJE01000005.1 - Region 4 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 655,196 - 702,955 nt. (total: 47,760 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 655195 - 702955:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_190014: pk
PKS_AT (924..1218): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 62.5%
inactive: 54.2%
Methylmalonyl-CoA: 54.2%

minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 58.4
Malonyl-CoA: 56.4
Methylmalonyl-CoA: 53.8
inactive: 47.3
Propionyl-CoA: 31.9
2-Methylbutyryl-CoA: 27.9
Ethylmalonyl-CoA: 26.2
CHC-CoA: 25.6
trans-1,2-CPDA: 19.5
Benzoyl-CoA: 18.9
Isobutyryl-CoA: 17.6
fatty_acid: 17.1
3-Methylbutyryl-CoA: 9.3
Acetyl-CoA: 8.6


ASPNIDRAFT_43740: pk
PKS_AT (1456..1651): pk
ATSignature: (unknown)
No matches above 50%

minowa: trans-1,2-CPDA
Prediction, score:
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0


ACJE01000005.1 - Region 5 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 718,650 - 740,255 nt. (total: 21,606 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000004.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 425,655 - 447,672 nt. (total: 22,018 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000004.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 594,272 - 640,699 nt. (total: 46,428 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location <594271 - >640699:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_171221: pk
PKS_AT (537..736): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 62.5%
Methylmalonyl-CoA: 54.2%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 38.3
Malonyl-CoA: 31.2
Methoxymalonyl-CoA: 29.5
Isobutyryl-CoA: 20.6
Propionyl-CoA: 19.0
CHC-CoA: 15.6
2-Methylbutyryl-CoA: 14.1
fatty_acid: 12.7
trans-1,2-CPDA: 12.3
Benzoyl-CoA: 11.5
Ethylmalonyl-CoA: 11.4
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


ACJE01000004.1 - Region 3 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,728,749 - 1,812,152 nt. (total: 83,404 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 1728748 - 1812152:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 1728748 - 1780625:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 5, location 1753170 - 1812152:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_196432: X
Search NORINE for peptide: strict or relaxed

AMP-binding (24..432): X
NRPSPredictor2: asp, asn, glu, gln, aad
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
iighrgvpak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_225574: pk
PKS_AT (582..886): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Propionyl-CoA: 62.5%
2-Methylbutyryl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 94.2
Methoxymalonyl-CoA: 79.4
Malonyl-CoA: 62.9
Ethylmalonyl-CoA: 57.9
Isobutyryl-CoA: 50.1
Propionyl-CoA: 46.8
Benzoyl-CoA: 39.8
fatty_acid: 36.8
trans-1,2-CPDA: 31.8
2-Methylbutyryl-CoA: 21.9
CHC-CoA: 19.8
3-Methylbutyryl-CoA: 11.9
Acetyl-CoA: 5.5
inactive: 0.0


ASPNIDRAFT_225587: pk
PKS_AT (539..850): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
CE-Malonyl-CoA: 62.5%
Methylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 69.7
Malonyl-CoA: 60.0
Methoxymalonyl-CoA: 50.7
Propionyl-CoA: 26.4
Isobutyryl-CoA: 25.3
Ethylmalonyl-CoA: 24.0
Acetyl-CoA: 21.4
3-Methylbutyryl-CoA: 21.0
Benzoyl-CoA: 19.5
fatty_acid: 17.4
2-Methylbutyryl-CoA: 17.3
trans-1,2-CPDA: 16.3
CHC-CoA: 14.4
inactive: 11.0


ACJE01000004.1 - Region 4 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 2,893,383 - 2,936,971 nt. (total: 43,589 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location <2893382 - >2936971:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(val) + (hydrophilic)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 7, location <2893382 - 2927251:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(val) + (hydrophilic)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 8, location <2901288 - >2936971:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(val) + (hydrophilic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_170963: val
Search NORINE for peptide: strict or relaxed

AMP-binding (57..453): val
NRPSPredictor2: val
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
val
Stachelhaus prediction details:
Stachelhaus sequence:
dlvftgsmfk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_171573: hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (59..465): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
vaefnggagk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000004.1 - Region 5 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 3,265,572 - 3,294,682 nt. (total: 29,111 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000004.1 - Region 6 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 3,680,765 - 3,724,529 nt. (total: 43,765 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 10, location 3680764 - 3724529:
Polymer prediction:
(hydrophilic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_170633: hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (101..359): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hasymgh--k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000003.1 - Region 1 - indole
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 460,314 - 481,306 nt. (total: 20,993 nt) Show pHMM detection rules used
indole: (indsynth or dmat or indole_PTase)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000003.1 - Region 2 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 586,604 - 638,938 nt. (total: 52,335 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location <586603 - >638938:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location <586603 - >631796:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location <599394 - >638938:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_128638: pk
PKS_AT (531..840): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 87.5%
Methylmalonyl-CoA: 70.8%
Ethylmalonyl-CoA: 62.5%

minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 73.2
Methylmalonyl-CoA: 72.4
Malonyl-CoA: 64.7
Ethylmalonyl-CoA: 50.6
Isobutyryl-CoA: 43.7
Propionyl-CoA: 43.3
inactive: 25.0
2-Methylbutyryl-CoA: 24.2
trans-1,2-CPDA: 20.0
Benzoyl-CoA: 14.9
CHC-CoA: 12.4
fatty_acid: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


ASPNIDRAFT_57223: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (29..418): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hllmyavlik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000003.1 - Region 3 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 682,321 - 752,972 nt. (total: 70,652 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 682320 - 752972:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(phe) + (pk - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_128601: pk - X
Search NORINE for peptide: strict or relaxed

PKS_AT (547..865): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 76.5
Methoxymalonyl-CoA: 69.0
Ethylmalonyl-CoA: 43.4
Malonyl-CoA: 38.3
Propionyl-CoA: 33.8
Benzoyl-CoA: 27.6
trans-1,2-CPDA: 26.0
Isobutyryl-CoA: 24.4
fatty_acid: 19.2
CHC-CoA: 11.8
2-Methylbutyryl-CoA: 2.6
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

AMP-binding (2937..3323): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
didmngcvwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_44880: phe
Search NORINE for peptide: strict or relaxed

AMP-binding (264..666): phe
NRPSPredictor2: phe
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
phe
Stachelhaus prediction details:
Stachelhaus sequence:
dawmfaatfk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000002.1 - Region 1 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 470,512 - 521,905 nt. (total: 51,394 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 470511 - 521905:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk - hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_41618: pk - hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

PKS_AT (545..864): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 70.8%
Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 90.8
Methoxymalonyl-CoA: 77.4
Ethylmalonyl-CoA: 60.9
Isobutyryl-CoA: 50.0
Benzoyl-CoA: 49.0
trans-1,2-CPDA: 44.9
Malonyl-CoA: 40.7
inactive: 32.2
Propionyl-CoA: 32.1
2-Methylbutyryl-CoA: 21.9
CHC-CoA: 14.8
fatty_acid: 14.6
Acetyl-CoA: 8.9
3-Methylbutyryl-CoA: 1.8

AMP-binding (2930..3339): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
gltllalfgk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000002.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 527,440 - 548,657 nt. (total: 21,218 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000002.1 - Region 3 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,157,902 - 1,203,466 nt. (total: 45,565 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 1157901 - 1203466:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - mal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_41846: X - mal
Search NORINE for peptide: strict or relaxed

AMP-binding (24..423): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmfvvglask
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

PKS_AT (1161..1455): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
inactive: 66.7%
Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 162.6
inactive: 74.8
Methoxymalonyl-CoA: 73.9
Methylmalonyl-CoA: 66.3
Isobutyryl-CoA: 42.7
Propionyl-CoA: 37.3
Acetyl-CoA: 31.3
Ethylmalonyl-CoA: 30.8
Benzoyl-CoA: 29.8
trans-1,2-CPDA: 28.8
CHC-CoA: 27.6
fatty_acid: 18.8
2-Methylbutyryl-CoA: 17.4
3-Methylbutyryl-CoA: 0.0


ACJE01000001.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 109,829 - 166,460 nt. (total: 56,632 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location <109828 - >166460:
Polymer prediction:
(hydrophobic-aromatic) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_188738: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (5..303): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
----liaglk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_43555: hydrophobic-aromatic
Search NORINE for peptide: strict or relaxed

AMP-binding (532..913): hydrophobic-aromatic
NRPSPredictor2: hydrophobic-aromatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aromatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dghiyvmcgk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000001.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 288,268 - 333,266 nt. (total: 44,999 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location <288267 - >333266:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_43495: pk
PKS_AT (463..751): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 66.7%
Methylmalonyl-CoA: 62.5%
Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 63.7
Methoxymalonyl-CoA: 58.3
Malonyl-CoA: 47.2
Isobutyryl-CoA: 41.9
Propionyl-CoA: 31.8
Benzoyl-CoA: 24.6
trans-1,2-CPDA: 22.0
2-Methylbutyryl-CoA: 17.0
fatty_acid: 14.0
Acetyl-CoA: 13.9
3-Methylbutyryl-CoA: 9.1
CHC-CoA: 8.1
inactive: 0.0
Ethylmalonyl-CoA: -3.7


ACJE01000001.1 - Region 3 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 375,131 - 480,312 nt. (total: 105,182 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 375130 - >480312:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk) + (hydrophobic-aliphatic) + (pk) + (redmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 375130 - 422976:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 5, location <419521 - >480312:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(hydrophobic-aliphatic) + (pk) + (redmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_212679: X
Search NORINE for peptide: strict or relaxed

AMP-binding (68..453): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvlfvggvak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_43457: pk
PKS_AT (1687..1946): pk
ATSignature: (unknown)
No matches above 50%

minowa: trans-1,2-CPDA
Prediction, score:
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0


ASPNIDRAFT_188806: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (21..441): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
aasargvcik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ASPNIDRAFT_56946: pk
PKS_AT (900..1196): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Ethylmalonyl-CoA: 54.2%
inactive: 54.2%

minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 60.7
Methylmalonyl-CoA: 49.7
Malonyl-CoA: 49.2
inactive: 44.2
trans-1,2-CPDA: 22.5
Propionyl-CoA: 22.4
Ethylmalonyl-CoA: 22.2
CHC-CoA: 21.8
Isobutyryl-CoA: 17.0
2-Methylbutyryl-CoA: 16.5
Benzoyl-CoA: 14.2
3-Methylbutyryl-CoA: 13.6
Acetyl-CoA: 11.0
fatty_acid: 0.0


ASPNIDRAFT_188817: redmal
PKS_AT (554..876): redmal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 66.7%
Methylmalonyl-CoA: 62.5%
Isobutyryl-CoA: 54.2%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 90.9
Methylmalonyl-CoA: 66.1
Methoxymalonyl-CoA: 65.2
Isobutyryl-CoA: 29.8
Benzoyl-CoA: 22.3
inactive: 22.1
trans-1,2-CPDA: 17.0
fatty_acid: 16.3
CHC-CoA: 16.2
Propionyl-CoA: 15.7
2-Methylbutyryl-CoA: 14.7
Ethylmalonyl-CoA: 5.9
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


ACJE01000001.1 - Region 4 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 588,981 - 607,418 nt. (total: 18,438 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000001.1 - Region 5 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,155,547 - 1,198,396 nt. (total: 42,850 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 7, location 1155546 - 1198396:
Polymer prediction:
(hydrophilic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_129581: hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (18..373): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
vamflgsagk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ACJE01000001.1 - Region 6 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,223,388 - 1,266,093 nt. (total: 42,706 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 8, location <1223387 - >1266093:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_188697: pk
PKS_AT (545..846): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 64.3
Methoxymalonyl-CoA: 59.4
Malonyl-CoA: 53.6
Isobutyryl-CoA: 35.5
Propionyl-CoA: 30.7
CHC-CoA: 25.1
fatty_acid: 22.6
2-Methylbutyryl-CoA: 22.0
Benzoyl-CoA: 17.9
inactive: 13.3
trans-1,2-CPDA: 10.0
3-Methylbutyryl-CoA: 7.2
Acetyl-CoA: 0.0
Ethylmalonyl-CoA: -2.2


ACJE01000001.1 - Region 7 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,321,446 - 1,368,125 nt. (total: 46,680 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 9, location 1321445 - 1368125:
Polymer prediction:
(mal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ASPNIDRAFT_56896: mal
PKS_AT (912..1211): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 100.0%
Methylmalonyl-CoA: 62.5%
Isobutyryl-CoA: 58.3%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 110.5
inactive: 48.6
Methoxymalonyl-CoA: 48.3
Methylmalonyl-CoA: 44.4
Propionyl-CoA: 19.9
Benzoyl-CoA: 17.2
2-Methylbutyryl-CoA: 15.8
Ethylmalonyl-CoA: 13.2
Isobutyryl-CoA: 12.5
CHC-CoA: 11.2
fatty_acid: 10.4
trans-1,2-CPDA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


ACJE01000001.1 - Region 8 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,416,084 - 1,434,356 nt. (total: 18,273 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

ACJE01000001.1 - Region 9 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,515,938 - 1,539,480 nt. (total: 23,543 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.