LOCUS       ACJE01000021.1         22214 bp    DNA     linear   PLN 19-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   ACJE01000021
VERSION     ACJE01000021.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 06:16:28
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3090656
            Orig. end    :: 3112870
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22214
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[<3100656:3100954](+),
                     [3101023:3101255](+), [3101324:>3102870](+)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(<10001..10298,10368..10599,10669..>12214)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..22214
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22214
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            join(<322..5299,5358..5846,5914..6029,6082..>6516)
                     /locus_tag="ASPNIDRAFT_37721"
                     /product="hypothetical protein"
     gene            <322..>6516
                     /locus_tag="ASPNIDRAFT_37721"
     CDS             join(<322..5299,5358..5846,5914..6029,6082..>6516)
                     /NRPS_PKS="Domain: SAT (150-381). E-value: 3.9e-13. Score:
                     41.2. Matches aSDomain:
                     nrpspksdomains_ASPNIDRAFT_37721_SAT.1"
                     /NRPS_PKS="Domain: PKS_AT (1621-1816). E-value: 1.6e-21.
                     Score: 68.6. Matches aSDomain:
                     nrpspksdomains_ASPNIDRAFT_37721_PKS_AT.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /codon_start=1
                     /db_xref="PFAM:PF00698"
                     /db_xref="PFAM:PF01575"
                     /db_xref="PFAM:PF08354"
                     /db_xref="PFAM:PF16073"
                     /db_xref="PFAM:PF17828"
                     /db_xref="PFAM:PF17951"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 29.8; E-value: 4.4e-09)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ASPNIDRAFT_37721"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ASPNIDRAFT_37721-T1"
                     /sec_met_domain="PKS_AT (E-value: 3.4e-20, bitscore: 68.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTATTELHPNPSPSPSGDGPSVAFTLEHGEATAALSVSSAVATTL
                     QPYRASWLADDTISPLSLTLSFLGHLTRQKAPLSAVQTAVRAFETQYLAGIDIHTAVTI
                     LPDALGAKKTALRDYYAAAAYTGQPLSNSPSALFKSAQTGTSRITTIFGGQGTANPSCV
                     RDLRSLYTTYRPILTQLMQECGPVLSSLSQRPDTQSYFRGRSIDLNSWLAGATTLNEDF
                     VSAAPVSLPILGLFDLAHYCVISSVLGQTPGQVATSMHAISGHSQGIVVAAAVARADSW
                     TSFYDNARLAVELLFWIGFESHQDAPQLFIAPELVEQTKEQGHGVPSPMLSVRGLERPA
                     LEKLLAQCNQVLPESRQLHIALINARTNHIVAGPAASLCGLSHVLAELQAAGEKDQTRI
                     PFSQRKPAVTHSFLPISTPFHTPYLQAASQRIKERLADRAFSADQLQVPVLHTATGEDL
                     RVNPQSNVIEALVDAITTEPVDFPGLLADATTTHFLVLGAGRLSELVKQIRQGYGQQII
                     AASELKPSSADIGSQADLFAPTLRPAPSSWADAYQPRLVQTANGRLILDTKLSRLLQVP
                     PIITAGMTPTTVPWDFVAAVINAGYFIELAGGGYHTEDEMRVAIEKIAAAIPPGRGITC
                     NLIYVNPKAIAWQTRLIRKLIRQGVPIDGLTIGAGVPSLEVAREYIDDLGIKHISFKPG
                     SVDAINAVLQIADDRPDFPIGLQWTGGRGGGHHSYEDFHAPILATYAEIRKRDNICLVA
                     GSGFGAGDDTYPYLTGQWSVARGYPAMPFDGILLGSRMMLCREAHTSPAVKQLLATTPG
                     VPDGEWEKSYKGSAGGIITVRSEMGQPIHKVATRGVRLWADFDQTLFRHPRPKMVEELA
                     KRKTEIIARLNKDYAKPWFGQDARGQPIDLADMTYAGVLARMVELMYVAHQQRWIHPSY
                     QRLVSDVAVRTLERVAPSVELSLDLLDAPASFLQVLSEKCPAAATQRLHPDDAAFFLRR
                     CQARGQKPVNFIPILDENFETWFKKDSLWQSEDLEAVVGQDPERVCILHGPVAVRYATD
                     KDESAQEILDGIATSHTHAALQDFYRGDLQRVPKVVNASAATSHTQPESSYEVSSLDLV
                     TDSSFSWVRDLLETPTIIREGIRKKNTFRSILAVKPGQKLVVNHTQQRIVLCESSTEQP
                     VISIQSDGTRTISVDLHQPSSFTAAPAVLSLQYKARSAGLSPALEEVVDGRNDRIKTFY
                     RNLWLGEAADPTKDSHSTFHGPEITLTRDLLEDMYRTLGLSPTGIRPESLPMDIAIVIA
                     WEPLVEPLVCAGVEGDLLRLVHRSNDIDYVPSATPFQVGDVLRSSSQIQSITIEPTGKS
                     IVVKATIERAGEPIAFVTSTFFMRGTYTDYASCFERITEPETMLEVSTPVDEELLRSRP
                     WLQLDEPTTPLVGKTLCFRLETSIDWKDQTTFQTLQTSGTVSLRSWNGKQTPIGRVSFE
                     ARDGKANPVSDFLRRRGQPLVARKPLEVTQELNQTSEGVQIPASNAGYSTFSKDFNPIH
                     ISSEFAQYVELPGTITHGMYTSAVVRAVTERCAAQGDLTRFRRWACSFVGMVLPSDQLE
                     VRVQHVAMIEGRLLLNVTAIKAGTDEAVIQAEAEVDQPSTVYVFTGQGSQSPGMGMSLY
                     KSSAAARAIWDAADKFFIETYGWSVLELVRQNPTALTVHFRGKRGRQIKANYMAMTIDA
                     YRADGTLVKEPILPELTPKSTSYTFADPRGLVFSTQFAQPLVLLLERAAVEDLRQRGVV
                     QGDAAFAGHSLGEYGALASFGEFMPFTDLLRVVFYRGLAMQVAIERDDQGRTNFSMAAV
                     NPARVGKFFTEKALRQIVTQIATTTHALLEIVNFNVDGEQYVCAGTLENLHALAAITDT
                     IARSPTGAALAREFTDATTIGNADLASTKLVEQCIAEARQLPAPVSLKRSLATIPLQGI
                     DVPFHSAHLRPGVASYRNFLEERIPKTEVDPQKLVGKWIPNVMGTPFSLSREYVEGVYG
                     LTQSPILKEVLAR"
     aSDomain        772..1464
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPNIDRAFT_37721_SAT.1"
                     /evalue="3.90E-13"
                     /label="ASPNIDRAFT_37721_SAT.1"
                     /locus_tag="ASPNIDRAFT_37721"
                     /score="41.2"
                     /tool="antismash"
                     /translation="IFGGQGTANPSCVRDLRSLYTTYRPILTQLMQECGPVLSSLSQRP
                     DTQSYFRGRSIDLNSWLAGATTLNEDFVSAAPVSLPILGLFDLAHYCVISSVLGQTPGQ
                     VATSMHAISGHSQGIVVAAAVARADSWTSFYDNARLAVELLFWIGFESHQDAPQLFIAP
                     ELVEQTKEQGHGVPSPMLSVRGLERPALEKLLAQCNQVLPESRQLHIALINARTNHIVA
                     GPAASLCGLS"
     CDS_motif       775..816
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_37721_0001"
                     /evalue="9.80E+00"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ASPNIDRAFT_37721"
                     /score="0.2"
                     /tool="antismash"
                     /translation="FGGQGTANPSCVRDL"
     CDS_motif       1099..1155
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_37721_0002"
                     /evalue="1.70E-03"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="ASPNIDRAFT_37721"
                     /score="11.3"
                     /tool="antismash"
                     /translation="HAISGHSQGIVVAAAVARAD"
     CDS_motif       5179..5235
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_37721_0003"
                     /evalue="1.60E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ASPNIDRAFT_37721"
                     /score="17.3"
                     /tool="antismash"
                     /translation="VYVFTGQGSQSPGMGMSLYK"
     aSDomain        join(5185..5299,5358..5827)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASPNIDRAFT_37721_PKS_AT.1"
                     /evalue="1.60E-21"
                     /label="ASPNIDRAFT_37721_PKS_AT.1"
                     /locus_tag="ASPNIDRAFT_37721"
                     /score="68.6"
                     /specificity="consensus: pk"
                     /specificity="Minowa: trans-1,2-CPDA"
                     /specificity="PKS signature: (unknown)"
                     /tool="antismash"
                     /translation="VFTGQGSQSPGMGMSLYKSSAAARAIWDAADKFFIETYGWSVLEL
                     VRQNPTALTVHFRGKRGRQIKANYMAMTIDAYRADGTLVKEPILPELTPKSTSYTFADP
                     RGLVFSTQFAQPLVLLLERAAVEDLRQRGVVQGDAAFAGHSLGEYGALASFGEFMPFTD
                     LLRVVFYRGLAMQVAIERDDQGRTNFSMAAVNP"
     CDS_motif       5660..5770
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASPNIDRAFT_37721_0004"
                     /evalue="7.20E-06"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ASPNIDRAFT_37721"
                     /score="17.9"
                     /tool="antismash"
                     /translation="AFAGHSLGEYGALASFGEFMPFTDLLRVVFYRGLAMQV"
     mRNA            join(<10001..10298,10368..10599,10669..>12214)
                     /locus_tag="ASPNIDRAFT_120113"
                     /product="hypothetical protein"
     gene            <10001..>12214
                     /locus_tag="ASPNIDRAFT_120113"
     CDS             join(<10001..10298,10368..10599,10669..>12214)
                     /codon_start=1
                     /db_xref="PFAM:PF00348"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Terpene_synth_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 126; E-value:
                     2.5e-38)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ASPNIDRAFT_120113"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ASPNIDRAFT_120113-T1"
                     /sec_met_domain="Terpene_synth_C (E-value: 1.5e-06,
                     bitscore: 23.8, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="TVSEPVEVWTHSQVLPEDDEHRKDCFTTLTPRIHKYDHVAQRGSD
                     RFVQDLTAALNLDEPQTSYLSSPVGNYASFLYPECLPERLETVAYLTELGNLHDGKQQG
                     KKTDESAESPRVAARKQLLEKAMSELSDKDKDGHEIIDCYRSNWLVTPEVPTAENCANL
                     DDYVARRRLNAGIDVYWTLMGFAHGTRLGKEDQAVVRDALDAAERTMFFTNDYYSWPKE
                     KRVSKKKPVANVILFLMEHQNMSEEDAVAKAKQLIIDNEHEFVRRREALYQANSDLAPQ
                     LRKWMEVLGASLAGIHYWCKNAPRYAVPETAEESEEEESSEEDGSDEEESSSDEDTDDD
                     DEEEEEEEEEKAAPVEVVPEPEESEEPVEVAVWTPLVTEEETPDVHLDTSALLAPSSYA
                     RSISRSTLHSDLLTSLNAWLQVPARPLAFIRQVITELQDSTGMLADVQDQAALRDQRTP
                     AHLVYGPAQCMNSAAYLFVRAARIVTSLNCPGMLDGLLQELEAHFVGQSWELNWRFSTH
                     CPGETEYLAMVDQKAGASFRLLTRLMQAASMGGATLDLEPFTKVLGRLSQIRHEYLGLL
                     ESAASDRSFGEDLDQAKVTYPIVRACNLDPAGRAVIFGIFRQKPAGTVLPIESKRQIVS
                     LVQQTGALQATYDLIRQLGREAMNTLSELETAAEELNPSLRAVVKSLVEVPAPDHL"
     mRNA            complement(join(<12495..13583,13655..>14026))
                     /locus_tag="ASPNIDRAFT_37719"
                     /product="aldehyde dehydrogenase"
     gene            complement(<12495..>14026)
                     /locus_tag="ASPNIDRAFT_37719"
     CDS             complement(join(<12495..13583,13655..>14026))
                     /codon_start=1
                     /db_xref="PFAM:PF00171"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 441.5; E-value:
                     4.8e-134)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ASPNIDRAFT_37719"
                     /product="aldehyde dehydrogenase"
                     /protein_id="ncbi_ASPNIDRAFT_37719-T1"
                     /transl_table=1
                     /translation="MSQSIPQHPGQRENIETRLFINGEFVPSLSGSKFDLYNPATEELS
                     ASVYEAGPEDVDRAVAAAKAAFPAWSETGALQRAQLLEKWADRLEACADEMAYLDAICM
                     GKPAYSDSKLIPSSFLSDRHALDITGESSLNTPGFVNVSLRQPFGVCGAIVPWNGPVVT
                     MIFKAAAALVTGNTIVIKSSEKAPLSCLVAARCAQEAGIPPGVFNMLSGFGRPCGEAIA
                     RHMEIRKISFTGSTATGRAIQKMAAESNLKSVTLELGGKSPLVIWDDADLSKAVPAAAM
                     SILTNSGQVCVASSRVYVHEAIAPQFLEQLKTTMTEMGKSGHPLIPGTTRGPQADAAQF
                     ARVQGYLDLAKQEGVSVYLGGEREGDKGYFVQPTILKDVPEESRLMKEEIFGPVVAVNT
                     FTDEEDVMARANDSEYGLYASIYTRDISRALRAAKKFEAGTVGVNCTSPTMAFDMPFGG
                     WKGSGEGRELSRYATDYWTELKSVLIAL"
     mRNA            <15286..>17094
                     /locus_tag="ASPNIDRAFT_177427"
                     /product="hypothetical protein"
     gene            <15286..>17094
                     /locus_tag="ASPNIDRAFT_177427"
     CDS             <15286..>17094
                     /codon_start=1
                     /db_xref="PFAM:PF01661"
                     /locus_tag="ASPNIDRAFT_177427"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ASPNIDRAFT_177427-T1"
                     /transl_table=1
                     /translation="MTGSLPSVLQTLLADSHYFSLQRSVCHHNHHRQHDIASIESMDSW
                     AQFRLMKQLLCVRHPRQSLPSSLLREIDQVLLEERANRLLLDAASIPALPTPSSSSKPL
                     PATLHLWQGDITTLDGVTAITNAANEQMLGCFQPAHRCLDNVIHARAGPRLREECFHHM
                     DQGQRTLPVGHACATKGYCLPAPYVIHTVGPQLDAGQPVPTAHQRQQLRQCYEAVLDVA
                     EALPASDPRGKSIALCGISTGLFAFPVEEAASIAIQSVLDWLRHHLHTSITNIIFNTFT
                     DTDTAVYQQTLKKMHYPVPSLVPPPRVHGSSLIQAKAWLAAADTILISCGAGISAATGL
                     DYTSTTLFDRHFPAFKQYQLRRLYDTFGRTNRDWPSESVRWGFYFSHLAMVRRWPRSSL
                     YTSLLKWLASRFQPDRVHVRTSNADGLFAAHGLPEAQLSTPQGQYAFLQCLENCRPDAV
                     FPSAPYLDAALPHLDPQTQVVTAQDKIPTCSFCGGAMSICVRAGDWFNERPFAPGETRW
                     HQFREAFLTDLTRNVVIIELGVGLSTPGVLRWENEELIEQGDGRVRLVRAGLGDAVQVP
                     GELAAAQLATSIEGDLQDVVRAIVAP"
     mRNA            join(<17702..19481,19538..>19815)
                     /locus_tag="ASPNIDRAFT_176790"
                     /product="amine oxidase"
     gene            <17702..>19815
                     /locus_tag="ASPNIDRAFT_176790"
     CDS             join(<17702..19481,19538..>19815)
                     /codon_start=1
                     /db_xref="PFAM:PF01593"
                     /locus_tag="ASPNIDRAFT_176790"
                     /note="SECRETED:SignalP(1-26); EggNog:ENOG41"
                     /product="amine oxidase"
                     /protein_id="ncbi_ASPNIDRAFT_176790-T1"
                     /transl_table=1
                     /translation="MPRYNWWYSPLVLGVIYSALVGAVSQHPPREVHRHVLNFQVPSLV
                     TADSLHNVHLDFLDSSFEGHINLFYGDCHTGQGHHEIGHIVIERDAHPERFVWITPADA
                     PHLHCLHAISGSTLLARSDPIPIATRLARRESIADVADVMGPWFDGVAYMQGKEPGKAV
                     VSAAKNSSVAIIGGGISGMMTSLLLNSVGMTNWHIVESSHRLGGRIRTHYLNDSRPDQY
                     QYQELGAMRLPMNITYADTNETLQIQDMRLVLQLADVLNELNADADPALRVNFIPFIQD
                     NPNLPTDTGGVRLPDGRIPTVAQVAANSSLAYTAPPDNASAVADAKAQYMQYAQTDKMG
                     KIREVARNMYRAHKAALEDGFYHWSEAAYMRYALGENADVVDYAAGTANNPIWDGFYDS
                     VYFAATTWFTIDQGMESLVRAFLPHVADKATLGRKVDGLSYNESSGKIAYTWRDSPVQI
                     TPERSEEYDYAVVAAPFTKVRMWELPRYSSILSRAISETNYEPACKLALLYKTRFWEYQ
                     EQPIFGGCGTVDIPGVQYVCYPSFNLNGTGPAAVLGAYSHGSPARSVQALKLEDWVALA
                     RRSMVEIHGAIAEEQFTGISHGHCWENDEHQNGAWTHPLVGQQEIFLPAYYQTEFQTIF
                     VGEHTTYTHGWIAAALDSAVRGTTQLLLDLGLVDEAKAIVHEWMGRWIEL"
     mRNA            complement(join(<20257..20316,20377..21447,21495..21664,
                     21715..21849,21901..>22069))
                     /locus_tag="ASPNIDRAFT_47223"
                     /product="hypothetical protein"
     gene            complement(<20257..>22069)
                     /locus_tag="ASPNIDRAFT_47223"
     CDS             complement(join(<20257..20316,20377..21447,21495..21664,
                     21715..21849,21901..>22069))
                     /codon_start=1
                     /db_xref="PFAM:PF07690"
                     /locus_tag="ASPNIDRAFT_47223"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ASPNIDRAFT_47223-T1"
                     /transl_table=1
                     /translation="MADKKIDVDCIEHVDQVLVDEAGRIQRLPVPSDDPNDPLNFALWE
                     KTGIVVCCCWFSIMSLSVIGGLGSVLDVFFQMYGAEGHSTNQVVWLSTFPSLFVGIGNY
                     IILPLALVCGRRPVMLIANTVLLGSLIGCALSQNWAQHFGLRILLGFATGATESLLPLM
                     LAEVTFIHQRGTIYGIYWATQNIVTSLLTLASSYEVAALGWRWFYWVFVITVAVGLVLV
                     VFACFETRFQRRPIFVGDHAVVTDQYGVTRVLTATETQEYLTSEEGRSYADLDGDTPPK
                     KTYRQMLSAWPRLCPHPLRDVLLTWWQMLETFSSPGIIYATLLSAVILGGSVGVSLTYD
                     TVLQYNYGWGAASIGLINLGGVFGGLGGMLYAGILGDRVIVWLARRAGGVHKPEHHLLL
                     LIFPGLLAVASLLLYGFTASGDATWGGPFMGWTLYQVAFVSTLIRTTSFATEAWEKNPG
                     PALVTVVGTKNIIGFGVSYGLNPMVAKYSYPAATGILAGVVGGVLLLGVPVYFYNPMWR
                     RYISQQRTRDRGQSGGP"
ORIGIN
        1 gaggaatcat ttgttgcctt tcaagtactt tatgaaatgt tgcattcagg gcagtggcgg
       61 gccggatctt gcatcctggc gtggttcggg tttcggccgc cggatgagac tctgcagcaa
      121 caccgaatca attgctgaga gatgcttttg ctgccgaaca gctttcaatc ggcaggattt
      181 ggtctgtctg actcagctat cgaagcaatg tgagacaacg aagtcagtct tataatcgac
      241 ctcaaaagct atctatctct ggcctcttct tcttgcccag gttgttgtta tcccgaccaa
      301 atgtcgccct agtcacccac catgactgcg acaaccgagc ttcatcccaa cccttcaccc
      361 tcgccttctg gggatgggcc atccgtggct tttaccctcg agcatggcga ggccactgcc
      421 gcgctgtctg tgagtagtgc tgtggccacc acactgcagc cctaccgcgc cagctggctg
      481 gccgacgaca ccatctctcc cctcagtcta acgctgtcct tcctcggcca tttgacccgc
      541 caaaaagccc ctctatcggc agtccagacc gctgtgaggg cctttgaaac acagtatctc
      601 gcaggcattg acatccacac ggctgtcact atcctgccag acgcccttgg tgccaaaaag
      661 actgccctgc gggattacta tgccgccgca gcctataccg gtcagccctt atccaactca
      721 cccagtgcct tgttcaaatc cgcccagaca ggcacctcac gcatcacaac aatctttggc
      781 ggccaaggaa cggccaatcc atcgtgtgtg cgcgatttac ggtctctcta taccacctac
      841 cgccccatac tcactcagct tatgcaagaa tgtggccctg tcctgtcctc tctgtcccag
      901 cgcccggaca cacagtccta ctttcgcggt cgttctatcg acttgaattc ctggctggcc
      961 ggcgcaacaa ccctcaatga ggactttgtc agcgccgcgc ctgtcagcct gcccattcta
     1021 ggactcttcg acctggccca ctactgcgtc atctccagtg ttttgggtca gacccccggg
     1081 caagtggcta cttcgatgca tgccatctct ggccattccc agggcattgt tgttgccgct
     1141 gctgtggctc gtgccgactc gtggacatcg ttctacgaca acgcccggct ggctgtcgag
     1201 ctgctgttct ggattggctt tgagagccac caagatgcgc ctcagttgtt catcgcgccc
     1261 gagcttgttg agcaaaccaa ggaacaaggg catggagttc cttcgccaat gctttccgtt
     1321 cgaggacttg agcggccagc actggaaaag cttctcgccc agtgtaatca ggttctccct
     1381 gagtcgcgcc agctgcatat cgccctcatt aatgcccgca caaaccacat cgtcgcaggt
     1441 cctgcagcgt cactgtgcgg tctcagtcat gttctcgccg agctgcaagc cgctggggag
     1501 aaggatcaga ctcgcatccc cttcagccaa cgcaagcccg ccgtcaccca ctccttcctc
     1561 cccatcagca ctcctttcca taccccctac ctgcaggcag cgtcccagcg cattaaggag
     1621 cggcttgccg atcgcgcgtt ttccgcagac cagctacaag ttcctgtttt gcacaccgcg
     1681 acgggtgaag atctacgagt caaccctcag tccaatgtca ttgaagccct cgtggatgcc
     1741 atcaccaccg agcccgttga cttccccggt ctgttggccg acgcaaccac cacccacttt
     1801 ctcgttctcg gggctggtcg cctcagcgag ctagtcaagc aaattagaca ggggtatggc
     1861 cagcagatca tcgccgccag cgagctcaag ccttccagtg ccgacatcgg tagccaggcc
     1921 gacctctttg caccaaccct ccgcccggct ccttcatcct gggcggacgc ctatcaacct
     1981 cgcctggtgc aaacggccaa cggccggttg atcctcgata cgaaactcag tcgcctgctg
     2041 caggtacccc cgatcatcac cgccggtatg acgcccacta ccgtgccctg ggacttcgtg
     2101 gcagctgtca tcaacgctgg ttactttatc gagctggccg gcggaggcta ccacaccgaa
     2161 gacgagatgc gggtcgccat cgagaagatc gctgccgcca ttcctcctgg ccgcggcatt
     2221 acctgcaatc tcatctacgt caatcccaag gcaatcgcct ggcagacacg gctgatccgc
     2281 aagctcatcc gccaaggagt acccattgac gggcttacta tcggtgccgg tgtgccgtcg
     2341 ctcgaggttg ctcgcgagta catcgacgac cttggcatca agcacatctc cttcaagcct
     2401 ggatcggtcg atgccatcaa cgctgtgctg cagatcgctg atgaccgacc cgacttcccc
     2461 atcggactcc agtggaccgg tggccgggga ggcggccatc actcgtatga ggacttccac
     2521 gcgcccatcc tggccaccta cgcggaaatt cgcaagcgtg acaacatctg cctcgttgcc
     2581 ggcagtggat ttggtgctgg agatgatacc tacccttacc tgaccggcca gtggtcagtt
     2641 gctcggggct accccgccat gccgtttgac ggtattttgt tgggcagccg catgatgctt
     2701 tgtcgcgaag cccacaccag tccagcagta aagcagctgc tcgccaccac acccggtgtt
     2761 cctgatggcg agtgggagaa gagctacaaa ggcagcgcgg gtggcatcat tacagttcgg
     2821 tcggaaatgg gccagcctat ccacaaggtg gccacgcgag gagtccggct gtgggccgac
     2881 tttgaccaga cgctgttccg ccaccctcgt ccgaagatgg tggaggagct ggccaagcgc
     2941 aagactgaaa tcattgcccg gctgaacaag gattatgcca aaccctggtt tggtcaggat
     3001 gcccgtggac agccgattga cctggcagac atgacttatg ctggagtgct ggcccgcatg
     3061 gttgagctga tgtatgtggc ccatcagcag cgctggatcc atccgtcata ccagcgcctg
     3121 gtgtcagatg tggccgtacg caccctcgaa cgcgtcgctc cgtccgtgga actgagcctt
     3181 gatctgctgg atgcaccagc tagtttcctg caggtgctgt ccgagaagtg tccagctgct
     3241 gccacgcaac gcctgcatcc cgacgatgcg gctttcttcc tgcggcgctg ccaggcgcgt
     3301 ggccagaagc ctgtcaattt cattccgatt ctggacgaga acttcgaaac atggttcaag
     3361 aaggattcgt tgtggcagtc agaggacctg gaggccgtcg tagggcagga tcctgagcgc
     3421 gtgtgcatct tgcatggccc tgttgccgtc cgctatgcca ccgacaagga cgagtcagcc
     3481 caggagatcc tcgacggcat tgcgacctcg catacccacg cggcactgca ggacttttac
     3541 cggggtgatc tccaacgagt gcctaaagtc gttaatgcat ctgccgccac ctcccatacc
     3601 cagcccgaat cttcgtatga agtgagctcc ctggatctgg tgacagacag ctcttttagc
     3661 tgggtacgtg accttctcga gacgcctact atcatccgcg aaggcatccg caagaagaac
     3721 acattccgca gcatcctggc tgtaaagcca ggtcagaagc tggtcgtcaa tcacacgcag
     3781 cagcgcatcg tcctctgtga aagcagcacg gaacagccag tgatcagcat acaaagcgat
     3841 ggtaccagga ccatttctgt ggaccttcat cagcccagca gctttaccgc tgcccctgca
     3901 gtcctctcac tccagtacaa ggctcgttcc gctggactct ctccagcgct ggaggaggtt
     3961 gtagacggac gcaatgaccg catcaagacc ttctaccgca acctttggct gggagaggcg
     4021 gcagacccta ccaaggatag ccactccacc ttccacggac ctgagataac cctcactcgc
     4081 gacctgctcg aggacatgta ccggactttg ggtctttcgc cgacgggcat ccgaccggaa
     4141 tctctgccca tggacatcgc cattgtgatc gcctgggaac cgctggtcga gccgcttgtc
     4201 tgcgcgggag ttgaagggga tctgctgcga ctcgtgcacc gctccaacga cattgactat
     4261 gtgccctccg ctacaccttt ccaggtcgga gatgtcctgc gctcgagtag ccagatccag
     4321 tccatcacca ttgagccgac aggcaagtcg atcgttgtga aggccaccat tgagcgggcc
     4381 ggagaaccca tcgccttcgt cacctccacc ttctttatgc gcggcacata caccgactat
     4441 gcctcctgct ttgaacgcat caccgaaccg gagaccatgc tcgaggtctc tactcccgta
     4501 gatgaggagc tgctgcgatc ccgaccgtgg cttcagttgg atgaacccac gaccccgctc
     4561 gtcggcaaga cgctctgctt ccgactggag acatccatcg actggaagga tcaaacgacc
     4621 ttccagacac ttcaaacgag cggtactgtc tccctccgct cctggaacgg caagcaaacg
     4681 cccatcggtc gggtctcctt cgaagctcgc gacggcaagg ccaatccggt gtcggacttc
     4741 ctacgtcgac gcgggcagcc actggtcgct cgcaagccgc tcgaagtcac tcaagagctg
     4801 aaccagacct cggagggcgt gcagattccc gcatccaacg cgggctatag taccttctcc
     4861 aaggacttca atcccattca catctcgtct gagtttgcac agtatgttga gttgcctggc
     4921 actatcactc atggcatgta cacgtcggct gtggtacgcg cagtcactga gcgctgtgcg
     4981 gcgcagggtg atctgacacg tttccgccgc tgggcctgct cgtttgtcgg catggtgctg
     5041 ccgagcgatc agctggaagt gcgcgtacag cacgtcgcta tgatcgaggg acgattgctg
     5101 ctgaatgtga cggccatcaa ggctgggacg gatgaagcgg tcatccaggc ggaggccgag
     5161 gtggatcagc cctcgacggt gtatgtcttt accggacaag gcagccagtc gccaggcatg
     5221 gggatgagcc tgtacaagtc cagtgcggct gcccgggcca tctgggacgc agcggacaag
     5281 ttcttcattg agacctacgg tatgtaatac cccttgtttt tctgtatccc ctctagcaag
     5341 ctaataatgg cattcaggat ggtcggttct cgagctcgtc cgccagaatc caacagcttt
     5401 gacggtgcac ttccggggca aacgcgggcg tcagatcaag gccaactata tggccatgac
     5461 tatcgatgca tacagggccg atggaacgtt ggtgaaggag cccattcttc cggaactcac
     5521 gcccaagtcc acttcataca catttgccga cccgcgcggt ttggtgttct cgacgcagtt
     5581 tgcacagcct ctggtcttgt tgttggagcg cgcggcggtc gaggatctcc gccagcgggg
     5641 agtagttcag ggggatgctg cgtttgcagg acactcactg ggcgaatatg gagcattggc
     5701 atcgtttggc gagtttatgc ccttcacgga tctcctgcga gtggtgttct atcggggttt
     5761 ggccatgcag gtggccattg agcgcgatga tcagggacgg acgaactttt ccatggcggc
     5821 ggtgaatccg gctcgtgtgg gcaagtgtga gtaaccattg atactctcct gtgtggatgt
     5881 ggggtttacc gtgaatgctg acatggggtt tagtcttcac ggagaaggca ttgcggcaga
     5941 ttgtgacaca gatcgctacg acaacgcacg ccctgctcga gattgtcaac ttcaatgtcg
     6001 atggcgagca atatgtgtgt gctggaacgg tgagttctct ttcccccaca acgaggtatg
     6061 ttctttcgct catgatatca gctcgagaac ctccatgccc tggccgccat caccgacact
     6121 attgcgcggt ctcctactgg ggctgctctc gcacgcgaat ttaccgacgc taccacgatc
     6181 ggtaatgcag accttgcatc gacgaagctg gtagagcaat gcattgcgga agcacgccag
     6241 ctccccgcgc cagtgagctt gaagcgcagc ctcgcgacaa ttcccctgca gggcatcgac
     6301 gtgcccttcc actcggcaca tctgcgaccg ggagtggcat cgtatcgcaa cttcttggag
     6361 gaacgtatcc ccaagactga ggtggatccg cagaagctgg tgggcaagtg gattcccaat
     6421 gtaatgggga cgccgttctc gcttagtcgg gagtatgtcg agggggtgta tgggctgacg
     6481 cagagtccga tcttgaagga ggtgctagca cgatagagaa gagtagggtt gtgctgtggg
     6541 cctttatgtg tatatgatag actgtctgac gattcgtctg tgtttcttgt taccttgtag
     6601 tagttggttg ctgtctactt ctaccctttt ggaatacatt taccaatcac tccaattatc
     6661 acagtacagt agaataacat tcccgcgcta gctgctctcg atataaagat actactcgag
     6721 tatgcttgac cgggtctttg ggttttgtag acatgttcgt gtctttatga ccctcgtccc
     6781 cggtggtcgc gttgtgcatc aatcttggat ccctttctct tttctacgcg cctctactgt
     6841 gtctttatat tcttggtgct cggtcggttg tttattgcaa gagataagaa aggaagtgga
     6901 attatatgaa atactattcc agttaagttc aaactagttc acttgcaaac aaccatagca
     6961 gcagtactag taggtgtttc ctagtactcc attatatatt ttggggcaac tcaggtatag
     7021 tactcgtatt acgtgttatg ttttttaaag taggccaaac agcgtgtgca tggaagaact
     7081 cagtggctcc ttgcatctta atcggacggg cttgaaaaga gatagggctt caataccata
     7141 tgttcaattg ttggacttat ggaggtacta cacgctgggc tcttcattca gagggtctac
     7201 ttggagattg actgtaagtg tgtcaactac ttgtaacaca agtattcact ccataatata
     7261 taccagcatc attggtctag tggtagaatt catcgttgcc atcgatgagg cccgtgttcg
     7321 attcacggat gatgcactct tcttttttcc tctttcctct ttttcccccc cgctcttcct
     7381 tcccagccat gtctattcgt tcattctact atctattttt gctatctcgt atctcctctc
     7441 ctctgtctgc tgtcaatcca cctccaatca tcgccagccc tcagactgcc gccctgcagc
     7501 tctcgggcct gccgatcgca acccaccgct gcagttcccc cactccacgg ctcatcttta
     7561 gcagaagttt agacctgcct atctgtctac tttgtgtctt ttggatggct gtctggttca
     7621 acggttatcc acagttgatc aagtgactct gttgccagtg gaacagctac cctgcaccta
     7681 actcttttct ctctcttcag ccacttgcca gccaacgggg tcccttctgc ctctgatatt
     7741 ggaggatgac gctatccatc tcgcacttct ctcgctgggt ttcgctggca gcttcacatt
     7801 ggcccgttga ggttgacatg actaactacg gttcaaagta gtgcaacggc tatcttctta
     7861 gcttaggatg gatgctcaga acgaatcatc gggccgggat tcgctggtga tcgggggtca
     7921 gccgagggga gatatgacga gcttccctgg aagtgccatc atcaaccttg gtgggagggg
     7981 caaaccagag gaggaaacga caaacgagta aggcaaagca aaggcaatgc aatgcaatgc
     8041 gagaaccaaa gcacagtcag tggattccac cttcacagag ggagaaagag aacaaaactc
     8101 accagagtaa ggcaatgatc cgcaaaccaa ggtccaatgg gaaacccgac ggagaattaa
     8161 caacgcccgg ttccaccgta aagatgtcag gttgattgcc ttggaggggg accctctctc
     8221 gtctcctctc tgtatctccc agaacttgtt ggaattaccc actgtggaaa aagtgatgct
     8281 atctcgggac aatgaggacc ctcctggccc gagcgtttgc agcctgcaga gattgtcgct
     8341 gggatcgctg gcagaaactc tacttctctc ctacaataac tttttcttct tttatctttt
     8401 caatcatctt ggaggggaaa ctaaacttaa acatgggaat agactttgga ttgatgccca
     8461 gccacattac tactcaagtt tatgtagccg agaaaatcat aatgtgactg gggatgggag
     8521 gctaacgaga gagatcgcac catctgcact catggtatga ctgaaccctc tccaagcgat
     8581 ggtaacgagg gcaaccacaa ccgcccattt gaacagtgac tgtgccagtg tcagtgccct
     8641 ccagagtctt taccgcgatc gcgatggcgt cgattccaac caaattgtta tgctttctcc
     8701 ctctcgggca ggtggggccg ttgcgtaact cggaattctg attgcatcgc gaaaccgaaa
     8761 atattcccca agcaaaaggt gtgagtgagt gatggatcga tggcagtgga agtgtaaaaa
     8821 gtagtgacta tcaagaagtt gtcgatcctg cggagtctat ctcctctccc agactacttt
     8881 gtgtactccg tactactttt tttttttact acgtatactt cctagtgctg cctgccatat
     8941 caacccctcc ctccgatcat catccttttt ctgactagat actgtagact tgttgactgc
     9001 ctaatcaact gaaaacgagc taactactcg gtagtctgcc ttgatagtct ttcgtagtct
     9061 tctgcaccac tccgatctct gctcgccagc caccgggaca ggcgatattt gcaaggcaat
     9121 ttggcccctc tacgaaccta ctttcgcccg acaagttgaa catgaaaaat cgaaagcaaa
     9181 aaatattcgc ccccgcggcg gacagatgaa ttctttcgca ccttcggaga caaaacatcg
     9241 tcatatctgc tggtggacat gcgttggccc aatgagaagg acagccagca gcgcgtcgag
     9301 gatgaagcgg tgaagggcac agcgatggag atccacatcg ggcaagccgt ggaggtgaag
     9361 ctaaaaaccc taacggcact aagaagacgc agaatgatca gaatcctcca tcccagcagc
     9421 taatggaccc acgaactgct gtagccgcaa gacagctgcc gttgtgtcgc caatcagcga
     9481 gctttcggcc gcgtagcttg catcccgtcc actcggcagc ttctcaactc ctccctcttc
     9541 gtttgctttt tttcgctgct actcactgct tctcggggac caactggagg tccatgctgt
     9601 tttccctttc gataaggatg tgaaaatttt tcttgttggt cagaccatga cgccgacacc
     9661 aatctggagg ggtggacatc tttgcgcatg agccagcgat ctcaaattgc tattaaagac
     9721 tccatctggt tcctcttctg ctccctcttt ctctcttccc tttcttcctt ttcaacttat
     9781 ccgcgtcgat cgcgttgtga aatattttta tattgtgacc gcattgctgg tcctgtatca
     9841 ctactcttat tacctttttc tttcaattgt tctgttgtga atcatcccaa tgttcaagca
     9901 gtactcccac atcctgtccc acaagaggcg tcgcagcagg ggaagcacca tcaaccaagt
     9961 cctgtcgggc gctcagtcgg agcctgcatc cgaagcagcc actgtcagcg agcccgtcga
    10021 agtatggacg cactcgcagg tgctgcccga ggatgatgag catcgcaagg actgcttcac
    10081 caccctgacc ccgcgcattc acaagtacga ccatgtcgcc cagcgcggca gcgatcgctt
    10141 cgtccaggac ctgacggcag cgctgaacct ggatgagccc cagaccagct acctttcctc
    10201 ccccgtcggc aactatgcca gcttcctcta cccagagtgt ctgcccgaac gtcttgagac
    10261 tgtcgcttat ttgacggaac tgggcaatct gcatgatggt atgtgaaacc ccattaatta
    10321 ccatcaccat ctcctggcat ggctcggacc caccactgac gtcttaggca aacaacaagg
    10381 caagaaaacc gatgaatccg ccgaatcccc ccgtgtcgct gcccggaagc aactgctgga
    10441 aaaggccatg tcggagctgt cggacaagga caaggatggc cacgagatca tcgactgcta
    10501 ccgcagtaac tggctggtca ccccggaggt ccccacggcc gagaactgcg ccaacctcga
    10561 cgactatgtc gcccggagac gcctcaatgc gggcattgag taagtcacct tcacctcccc
    10621 cccttgcata gccatacata tacaatggat tgctaacgtg gataccagcg tctactggac
    10681 cctcatgggc ttcgcgcacg gcactcgtct cggaaaagag gaccaggcgg tggtgcgcga
    10741 cgcactggat gccgccgagc gcaccatgtt cttcaccaac gactactaca gctggcccaa
    10801 ggagaagcgc gtctccaaga agaagcccgt cgccaacgtg attctcttcc tcatggaaca
    10861 ccagaacatg tccgaggagg atgccgtcgc caaggcgaag cagctgatca tcgacaacga
    10921 gcacgagttt gtccgccgtc gcgaggcgct ctaccaggcc aactcggacc tggcaccaca
    10981 gctccgcaaa tggatggagg tgctgggcgc ctccctggct ggtattcact actggtgtaa
    11041 gaatgctccg cgctatgcgg tccccgaaac cgcagaggag agtgaagagg aggagtcgtc
    11101 cgaggaagat ggctctgatg aggaagaatc ttcctctgac gaagacaccg acgacgacga
    11161 cgaggaagag gaagaggaag aggaagaaaa ggctgcaccc gttgaggtgg tgccggaacc
    11221 cgaggagagt gaggaacccg tggaggtggc tgtctggact cccctggtca ccgaggagga
    11281 aacccccgac gtgcatctgg atacctccgc cctgctggcc cccagcagct acgcccgctc
    11341 gatttcccgc agcaccctgc acagtgatct gctcacatct ctgaatgcct ggctgcaggt
    11401 ccccgcccgc ccgctggcct tcattcgcca ggttatcacc gagctgcagg actcgaccgg
    11461 catgctggcc gacgtgcagg accaagccgc gctgcgcgac cagcgcaccc cggcccacct
    11521 ggtgtacgga cccgcacagt gcatgaacag tgcggcgtac ctgtttgtgc gcgccgcccg
    11581 cattgtcacc agcctcaact gccccggcat gctggacggg ctgctgcagg aactggaggc
    11641 gcactttgtc ggccagtcgt gggagctgaa ctggcgcttc tcgacccact gccccggcga
    11701 gaccgagtat ctggccatgg tggaccagaa ggccggcgcc agcttccgtc tgctgacgcg
    11761 cctcatgcag gcggccagca tgggcggcgc gaccctggac ttggagcctt tcaccaaggt
    11821 gctgggtcgc ttgtcgcaga tccgccacga gtacctgggt ctgctggagt ccgcggccag
    11881 cgaccgctcg ttcggcgagg acctggatca ggccaaggtg acgtacccca tcgtgcgggc
    11941 ctgcaacctg gaccctgctg gccgggcggt catctttggc atcttccgcc agaagccggc
    12001 gggcacggtc ctccccatcg agagtaagcg ccagatcgtg tcgctggtgc aacagaccgg
    12061 ggcgctgcag gccacctacg acctgatccg gcagctgggc cgcgaggcca tgaacacgct
    12121 gagcgagctg gagacggcgg cggaggagct gaacccgtcg ttgcgcgcgg tggtgaagtc
    12181 tctggttgag gtgccggccc cggatcacct gtaaaaaaat ttgatacctt tgacggagac
    12241 gatgcatggt ggttgatacg atgatgatga cgatgatgag gatgacactc cttgtttctc
    12301 taatgtctac atgtctattt tcctttggcg tttttctgtg atgatgattt acgagacttt
    12361 ccttgatgta cggctatgag atgatatgat taatgacgat tatattcaag tattcgaacg
    12421 actgccttgt gtaaacatgt agaaagaaga gtcttattct cagtacacag tattatcgct
    12481 acaaacatca tgaattacaa cgcaatcaac accgacttca gctcggtcca gtagtctgtg
    12541 gcatatcgac tcagctctcg tccctctcca ctgcccttcc agcccccaaa tggcatgtca
    12601 aacgccatgg ttggactggt gcagttgact cccacggtgc cggcctcgaa cttcttggct
    12661 gcccgcagcg cccgcgagat atcccgcgtg tatatactgg catacagccc gtactcgctg
    12721 tcgttggcgc gtgccatcac gtcttcctcg tcggtgaagg tgttgacggc caccacggga
    12781 ccgaaaatct cctccttcat caagcgcgac tcctccggca catctttcag gatggtcggc
    12841 tgcacaaagt accctttgtc gccctcgcgc tcaccgccca agtacaccga gacaccttct
    12901 tgcttcgcca ggtccaggta gccctgcacg cgcgcaaact gggcggcatc ggcctgcggg
    12961 ccgcgcgtgg tacccgggat gagagggtgg ccactcttgc ccatctccgt catggtggtc
    13021 ttgagctgct cgaggaactg aggggcaata gcctcgtgca cgtagacccg cgagctggca
    13081 acgcagacct ggccggaatt ggtgaggatg gacatggcgg cggccggcac ggccttgctc
    13141 agatcggcat catcccagat caccagcggg gacttgccgc ccagctcgag ggtgacgctc
    13201 ttgaggttcg attcggcagc catcttctgg atggcgcgac ccgtggcggt cgagccggtg
    13261 aaggagatct tgcggatctc catgtgacgg gcaatggcct cgccgcaagg gcgaccaaag
    13321 ccgctaagca tgttgaagac gcccgggggg atgcctgctt cctgagcaca gcgagcagcc
    13381 accaggcaac tcagaggggc cttttcggag gacttgatga cgatggtgtt gccggtgact
    13441 aaggccgcgg cagccttaaa gatcatggtc acgacggggc cattccaggg gacaatggca
    13501 ccacaaacgc caaagggttg gcgcaagctg acattgacga agccgggagt attcaaggag
    13561 gattcgccag tgatatcaag ggccttggca gcatagaccc tcacgaagag gggcatgatg
    13621 cggccgacgt ctgggttttg gtcatgagtt agacatgtct gtctgatagg aatgacgagg
    13681 gaatgagctt actgtcactg taagcgggtt tgcccatgca aatggcatca aggtaggcca
    13741 tctcatcggc gcatgcctcc agacgatcgg cccatttctc cagtaactgg gcccgctgca
    13801 gggctcccgt ttccgaccag gctgggaagg cggctttggc ggctgcaacg gcgcgatcaa
    13861 catcctcggg accggcttcg tagaccgagg cactcagctc ctcggtggca gggttgtaca
    13921 gatcaaactt ggaccccgag agggagggga caaactcgcc gttgatgaag aggcgagtct
    13981 caatgttctc ccgctggccg ggatgttggg ggatggattg agacatgatg ataacaactc
    14041 aataaagtga atgaagagga aatagatgtg agtattgaca ggtaggagag caagagggcc
    14101 atgatgaccg ggttaatata cgaaaattaa aggatattag gccaaccgca gcaatgaggg
    14161 gttatgatgg ctcggcctct gcactaatgc actggtgtaa ccgattcctc ctatgagagt
    14221 cccaaagcaa attcgtatcc ctgaaagatc gtcatccgtg gctccatgat cgaggagctc
    14281 tgacattcca gatgtttttg gatgctgtca tgggatgaga gttgcttgcc gttctttgag
    14341 acagctcgac aggggagaga gcctgctgct gactgccgtg gagtcactag tcactagcta
    14401 ttccgcatgc gggatagagt ttcaagcaca cgaagatctc gcccccaagc tactaatagc
    14461 tactatggta cattatgctg acggtctgga tgtatggcct ggctcgtctc aagtggggcg
    14521 ctgagagctg aagtatgaag tgagttgttc gatggaaatg atatattagt aactactaat
    14581 agccatccct tgatgtggga ctgagacgca gactatattg cgatgtcctt cattgttcag
    14641 agggagcaca aaagtcctgg atggttgcac aattcagtcg gtatgattgc ctcctggcat
    14701 gagtggttga atgattcctt gcgacagcgt catcaccatg gttgttgaat gtcatcctgt
    14761 catcccctcg agtggcggag atagggacgg atatcggagt tatcgtatcc ggggatgatg
    14821 gtggttgtct cgacctgttc catcaggcta taatattggt agtaagatga agatgatgag
    14881 gtgtaaatgc tgcagtcaga aaaaaaggaa tgtgactagc catctttgtt tctttatgcc
    14941 agcattgccg atgattctgg ttatataatt atgttggcct gtccatcacg gcggaatttc
    15001 cccccgagtg gataacacct tcccattccg gaaatatgtc ccgtctagac aaacagtgca
    15061 aatgtaacat acagtggttc cacaaaaata catggtattt gcattatgga caaacagaac
    15121 aagccagata aacccgctca atgccaataa taactatgga acgatcgaag gggaatcgat
    15181 gagggaaaga gagctacaaa agacccccaa tatccccctg aataaagatg ggaacttctt
    15241 tcgagatgta tcttccacta aaattgtcaa acatctctgt cagtcatgac tggctcacta
    15301 ccgtcagtcc tgcagacctt actggctgat tcccactact tctccctgca gagatccgtc
    15361 tgccaccata accaccaccg ccagcatgac atcgcctcca tcgaatccat ggattcatgg
    15421 gcccagttcc gtctcatgaa gcagctgctc tgtgtcaggc atcctcgcca gtctcttcca
    15481 tcctccttac tccgggagat tgatcaggtg ttgcttgagg aacgtgccaa tcgccttctt
    15541 cttgacgctg cttccattcc agctcttcca actccatcat catcatcaaa gcctctcccc
    15601 gccacgctcc atctgtggca aggagacatt accacgttgg atggcgttac tgccatcacc
    15661 aatgcggcca acgagcagat gctgggatgt ttccagccgg cccatcgatg cctggacaat
    15721 gtcatccatg cccgggcagg tccccgcttg cgcgaagaat gtttccacca catggatcag
    15781 ggacagcgca ccttgcccgt cggccacgca tgtgccacca aaggatactg tcttcctgcc
    15841 ccctatgtga ttcacaccgt aggccctcag ctggacgcgg gacagcctgt gcccaccgcg
    15901 caccaacgtc aacagctgcg gcaatgctat gaggccgtcc tggatgtcgc agaagctctg
    15961 cctgcatcgg atcctcgggg caagtccatt gctctttgtg gcatctcgac cggactgttt
    16021 gcctttcccg tggaggaggc tgcatccatt gccattcaat ccgttctcga ctggctgcgg
    16081 caccatctgc acacctccat caccaacatc atcttcaaca ccttcaccga caccgacacg
    16141 gccgtctacc aacagacact caaaaaaatg cactatccag ttccttccct agtgccacct
    16201 ccccgggtcc atggatcctc ccttatccaa gccaaagctt ggctggctgc tgccgatacc
    16261 attttgatca gctgcggagc cgggatctcg gcggccactg gactcgacta tacctcgacc
    16321 actctgttcg atcgccactt cccggcattc aagcaatacc agctgcgacg gctgtatgat
    16381 acctttggcc gcaccaaccg tgactggcca tctgagagcg tccgctgggg attttacttc
    16441 tcccatctgg ccatggtgcg tcgctggccc cgctcgtccc tctatacctc gctgctaaaa
    16501 tggctggcat cacgttttca accggatcgg gttcacgtgc ggacctccaa tgcagacgga
    16561 ctctttgcag ctcatggact gcccgaagcg cagctctcca caccccaggg ccagtatgcc
    16621 ttccttcaat gtctggaaaa ctgccgtccg gatgctgtct tcccatcggc accgtatctt
    16681 gacgctgccc tgccgcatct ggatccacag acacaggtcg taacggcgca ggacaaaatc
    16741 ccaacatgtt cattctgtgg tggcgccatg tcgatctgtg ttcgggcggg agactggttc
    16801 aacgaacgac ccttcgctcc cggcgaaacg cgatggcacc aattccgcga ggcctttctc
    16861 acggatctga cacgaaacgt agttattatt gagctgggtg tcggcctttc cacgccaggg
    16921 gtgctgcggt gggagaatga ggagctgatc gagcagggcg atggacgcgt acggctggtg
    16981 cgcgcgggtt tgggcgatgc cgtgcaggtc cctggggagc tggctgctgc gcagctggcc
    17041 accagcatcg aaggggactt gcaggatgtg gttcgggcga tagtggctcc gtagactggc
    17101 caagtgacat gtagatgtga tacatctaat ttgctaaagc gattctttgc tggactttgc
    17161 tgtttcttcc tgacatggtc tatatatttc tccgggtacg gtagtccatc agctacacat
    17221 gcgtataact accaaagcag ttttctgtcc tgcgcgatgg ccttccatcg aatggaattg
    17281 tgaccattcc gtgaaatagc caggaggatg tgatccaagt cgggttagtc ccgtcgttct
    17341 ctccgcacca ggcaatgtgg ctgtcgaaga tcggcttttg gcgcaaattt ccgagcggca
    17401 attattgaaa ctagttcggc gggtcaccac caagtttggc cttcagaaat agacacgcaa
    17461 atggcagcgt gtcagactgc aataaatcaa cggcacccat aaacccctgt atctgcagga
    17521 tcctcaatta ttgatatctt cttatgtaga cacacatcat gtagggtaat tgaaagactg
    17581 agttagtgat gagaactcgg tggtaatctg gaatggcgcc ggtataaaat catgcatggc
    17641 atccgtacaa tcacccccgt catccgggca gagtgtgctg acctcaatac ctcggcgcgc
    17701 catgcctcgc tacaactggt ggtattctcc gcttgtcctg ggcgtgatat atagcgcctt
    17761 ggtaggcgca gtttcccaac atccccccag agaggttcac agacatgtcc tgaattttca
    17821 ggtgccgagc ctggtcaccg cagactccct gcacaacgtt catctggact ttctggacag
    17881 tagctttgaa ggtcatatca atctgttcta cggggactgc cataccggcc aggggcatca
    17941 tgagatcggc cacattgtca tcgagcgtga cgctcatcca gagcgcttcg tctggatcac
    18001 acccgccgat gcgcctcatc tgcactgcct ccacgccatt tctggatcga ctctgctcgc
    18061 tcgttccgat cccattccaa ttgccacccg cttggctcgt cgggaaagca tcgccgacgt
    18121 ggctgatgtg atgggcccct ggtttgacgg cgtcgcgtac atgcaaggca aggaacccgg
    18181 aaaggctgtg gtgtcggcag caaagaactc ttccgtggct attatcggcg gtggcatctc
    18241 cggaatgatg acaagtctgc tgctcaactc tgtcggcatg accaattggc acattgtgga
    18301 gtcatcccat cgactaggtg gccgcattcg cactcactat ctgaacgatt cgcggcccga
    18361 tcagtaccaa taccaggagt tgggggctat gcgccttccc atgaacatca cctacgccga
    18421 taccaacgag acactccaga tccaggacat gcgactagtc cttcagttgg ccgatgtcct
    18481 caatgagctc aacgccgacg ctgatccagc gctgcgagtc aacttcattc ctttcatcca
    18541 ggataatccg aatcttccga ctgacacggg aggtgttcgt ctgccagacg gccgaatccc
    18601 tactgtagcc caggttgccg ccaactcgtc gctggcatac acggcgcctc ccgacaacgc
    18661 cagtgccgtt gcggacgcca aagctcagta catgcagtac gcccagacag acaagatggg
    18721 taagatccgg gaggttgctc gcaacatgta ccgcgcacac aaagcggctc tggaagacgg
    18781 gttctaccac tggtcggaag ccgcatatat gcggtacgcg ctgggggaga acgcagatgt
    18841 cgtcgactac gccgctggca cggccaacaa tcccatttgg gatggattct acgatagtgt
    18901 ctactttgcg gccaccacct ggtttaccat cgaccagggg atggagtctc tggtgcgagc
    18961 attcctaccg cacgtcgcag acaaagccac cctcgggcgg aaagtggacg ggctctcgta
    19021 caacgagagt tcgggcaaga ttgcctacac ctggcgcgac tctccggtcc aaatcacccc
    19081 cgagcgcagc gaagaatatg actatgctgt cgtggccgcg cctttcacca aggtgcgcat
    19141 gtgggaattg ccgcgatatt cgtcgatcct gagccgggcc atctccgaga caaactatga
    19201 acccgcctgt aagctcgccc tgctgtataa aacccgcttc tgggagtacc aggaacagcc
    19261 catcttcggg ggctgcggca ctgtggacat tccgggggtg caatatgtat gctatccatc
    19321 gttcaatctg aatggtaccg gcccggcggc ggttcttggg gcatattccc atggaagccc
    19381 ggcgcggagt gtacaggcgt tgaaactcga ggattgggtc gcattggcac ggcgcagcat
    19441 ggtggagatt cacggggcga ttgcagagga acaattcaca ggtaggccgg atcctttgaa
    19501 taagtagccc tcagtctcat gcttactgtc ccgataggta tctcccatgg tcactgctgg
    19561 gagaatgatg aacaccaaaa cggcgcctgg acacaccccc ttgttgggca gcaagagatt
    19621 ttcctgcccg cctactacca aaccgagttc cagaccattt tcgttggcga gcataccacg
    19681 tatacccatg gctggatcgc cgcggctcta gactccgccg tgcgcgggac tacccaactc
    19741 ttgctggacc tggggctggt ggatgaggcc aaggcgattg tgcatgagtg gatgggtcga
    19801 tggattgaat tgtaagatat accggagctc agaagtgtac aatctcaaaa tacaatagat
    19861 tttttcgttc acacttccag gtaatttaga ttgtgtctgg gctaggatta tagcgaatcg
    19921 ggggttctcg ggcagcaccg aacagccgac ggtgcctccg aagtgcacgg tcatgccccg
    19981 aaggagcagt tgtagatccc ccactttccg accgtcaacg tagtaatcca cggcgtcggt
    20041 cacctaggaa gccattagag aagatcagta gacttgtgtt cgtagcgtct gttttgtatg
    20101 gttatgacag tcgtagtcag atatgattat agcaggtcta cgagtataca atccagcgag
    20161 tagtgtatcc cgacgattct gtattccgag aacacaatgc agaacatcca agtatcttgc
    20221 tgtataacat acaaatgaga gcgtccatcc ttcccattac ggtcctccag attgcccccg
    20281 gtcgcgtgtt cgttgctggc tgatataccg tctccactga acctaagtta gcatagctgc
    20341 atctccgaaa atcatcagca aaaggcgggt aagtaccatt ggattgtaga agtagacggg
    20401 aacccccaac agcagaactc cacccaccac ccccgccaga attcccgtgg ctgccggata
    20461 actatacttg gccaccatgg gattcaaacc atagctgacc ccaaagccta tgatgttctt
    20521 cgtccccacg accgtcacca gcgccggacc aggattcttc tcccatgcct ccgtggcaaa
    20581 cgatgtcgtg cggatgaggg tcgaaacgaa ggctacctga tagagcgtcc agcccatgaa
    20641 aggcccgccc caagtcgcat cgccgctggc ggtgaatcca tataatagca gcgaggctac
    20701 tgccaacagc cctgggaaaa tcaataagag gagatgatgt tcgggtttat gaaccccccc
    20761 ggcgcgtcgg gccaaccaaa caatgacacg gtcgcccaag atccccgcgt agagcatgcc
    20821 gcccagccct ccaaagacgc cgcctaagtt gatgaggcca atgctggcgg caccccagcc
    20881 gtagttgtac tgcaagactg tgtcataggt gagagagaca ccgacggacc cgcctaggat
    20941 gacagcagag agcagtgtgg catagatgat gccgggcgag ctgaaggtct cgagcatctg
    21001 ccaccaggtg agcaggacgt cgcgcagggg atgagggcag aggcgtggcc aagcgctgag
    21061 catctggcgg taggttttct tgggaggcgt gtcgccgtcg aggtcggcgt aagagcgacc
    21121 ctcttcacta gtgaggtatt cttgggtttc tgtggcagtc aggactcggg tcactccata
    21181 ttgatcggtg acgacggcgt ggtcgcccac gaagattggc cgacgctgga accgcgtctc
    21241 aaagcaggca aacaccacca gcaccagtcc gacggcgacg gttataacaa acacccagta
    21301 gaaccagcgc cagcctagcg cagctacttc atatgagcta gccagcgtca gaaggctcgt
    21361 cacgatgttc tgagtggccc agtagatgcc atagatggtg ccgcgctggt gaatgaaggt
    21421 tacctctgcc aacatcagag ggagaagcta tggtaggtta gatcaaccac aaaaaagaaa
    21481 tacagctgtc gcaccgattc cgtcgctcct gtagcgaatc ccaaaaggat gcgtagccca
    21541 aaatgctggg cccagttctg tgacaaggca cagccgatca acgaccccag caggacggtg
    21601 ttggcgatga gcatcaccgg tcgacgtccg cagacaaggg ctaacggcag gatgatgtag
    21661 ttccctgaca ctggtgagtt gctgacggta gcagaactgg aaaagacacc ttaccaattc
    21721 cgacaaatag tgaggggaaa gtcgagagcc aaacaacctg gttggtgctg tgaccttctg
    21781 cgccgtacat ctgaaagaaa acatccagaa cagagcccag cccaccaatg accgagagtg
    21841 acatgatagc tgagagaatg agcttgaact caatagtcaa ttggggggaa gggaacttac
    21901 aaaaccaaca acagcacacc acgatgcctg tcttctccca cagtgcaaag ttcaaggggt
    21961 cattgggatc gtcgctgggc accggcagac gctggatgcg accggcctcg tccaccagca
    22021 cctgatcaac atgctcgatg caatcgacat caatcttctt gtcggccatt ctgccggata
    22081 ctcctgcttg aacaacaaat gggtctcatc gcagcgcgcg acggagggtt ttaagctcgc
    22141 cgcttgtgtc cactcccgaa gagactaagc atattttaga gaatgcgggg aagatatggg
    22201 gaatgctgga cacg
//
