Aspergillus_niger_ATCC_10864 - 90 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

MCQH01000199 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS,T1PKS	1	39,373
Region 1.2	T1PKS	320,151	367,973	pyripyropene A	Terpene + Polyketide	25%
Region 1.3	NRPS-like	493,262	536,048
Region 1.4	terpene	699,828	721,143

MCQH01000066 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	indole	356,685	378,135
Region 2.2	bacteriocin	513,777	524,467
Region 2.3	terpene	939,499	960,994
Region 2.4	NRPS,T1PKS	964,901	1,016,922
Region 2.5	T1PKS	1,147,357	1,192,738	TAN-1612 / 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione / desmethyl TAN-1612	Polyketide:Iterative type I	100%

MCQH01000172 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 13.1	NRPS-like	32,213	75,319

MCQH01000169 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 23.1	T1PKS	154,786	198,427
Region 23.2	NRPS	246,718	293,376
Region 23.3	NRPS-like	323,374	366,394
Region 23.4	T1PKS	375,265	421,161	duclauxin	Polyketide	50%
Region 23.5	T1PKS	442,842	491,317
Region 23.6	terpene	526,681	548,296

MCQH01000231 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 34.1	NRPS	1,708,161	1,755,237

MCQH01000306 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 56.1	T1PKS,NRPS	157,937	210,080	phyllostictine A / phyllostictine B	NRP + Polyketide	20%
Region 56.2	NRPS-like	421,803	465,183
Region 56.3	terpene	552,528	574,528

MCQH01000015 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 58.1	NRPS	304,537	348,970
Region 58.2	terpene	473,694	495,391	shearinine D	Terpene	9%
Region 58.3	NRPS,terpene	499,395	546,460

MCQH01000072 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 61.1	terpene	61,134	83,690
Region 61.2	NRPS-like	104,680	147,775

MCQH01000184 (Aspergillus niger)

Region	Type	From	To
Region 62.1	terpene	179,639	200,874
Region 62.2	T1PKS	530,461	571,795
Region 62.3	T1PKS	944,298	988,044
Region 62.4	T1PKS	1,160,304	1,203,858

MCQH01000164 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 63.1	T1PKS	116,070	163,561
Region 63.2	terpene	907,330	928,286

MCQH01000074 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 64.1	NRPS	241,964	295,201

MCQH01000209 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 65.1	siderophore	138,707	150,850
Region 65.2	NRPS-like	161,354	205,839

MCQH01000246 (Aspergillus niger)

Region	Type	From	To
Region 66.1	NRPS	318,822	377,842
Region 66.2	T3PKS	542,535	583,761
Region 66.3	terpene	696,598	718,921

MCQH01000170 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 69.1	NRPS,T1PKS	1	50,437	dihydroisoflavipucine / isoflavipucine	NRP + Polyketide:Iterative type I	12%
Region 69.2	terpene	155,002	177,008
Region 69.3	T1PKS	194,178	238,570
Region 69.4	indole	542,326	563,685

MCQH01000155 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 70.1	T1PKS	211,721	257,593
Region 70.2	NRPS,T1PKS	294,162	400,133	azanigerone A	Polyketide	100%
Region 70.3	T1PKS	461,399	506,762	yanuthone D	Polyketide	100%

MCQH01000051 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 71.1	NRPS,T1PKS	203,741	274,367	AbT1	NRP	100%
Region 71.2	NRPS-like,T1PKS	316,324	371,653	notoamide A	NRP	11%

MCQH01000048 (Aspergillus niger)

Region	Type	From	To
Region 72.1	T1PKS	94,885	139,264
Region 72.2	NRPS	141,032	193,111
Region 72.3	T1PKS,NRPS-like	846,882	895,457

MCQH01000166 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 73.1	T1PKS,NRPS	722,119	774,080	pyranonigrin E	Polyketide	100%

MCQH01000208 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 74.1	T1PKS	1	32,499	naphthopyrone	Polyketide	100%
Region 74.2	terpene	80,467	98,791
Region 74.3	terpene	180,163	202,479	clavaric acid	Terpene	100%

MCQH01000210 (Aspergillus niger)

Region	Type	From	To
Region 75.1	NRPS-like	2,968	27,539
Region 75.2	terpene	55,641	77,041
Region 75.3	NRPS-like	199,298	242,627

MCQH01000027 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 76.1	NRPS	468,273	514,268
Region 76.2	betalactone	874,384	903,492

MCQH01000240 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 77.1	T1PKS,NRPS-like	253,287	310,174

MCQH01000245 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 78.1	NRPS-like	19,917	63,710

MCQH01000204 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 79.1	T1PKS,NRPS	496,071	547,464
Region 79.2	terpene	553,020	565,334

MCQH01000009 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 80.1	NRPS	60,091	120,022

MCQH01000196 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 81.1	T1PKS	322,303	361,913	aflavarin	Polyketide	60%
Region 81.2	T1PKS	432,388	480,880

MCQH01000006 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 84.1	siderophore	299,102	311,168
Region 84.2	NRPS	379,928	434,404
Region 84.3	NRPS,T1PKS	600,981	707,938
Region 84.4	T1PKS	797,634	845,399	ankaflavin / monascin / rubropunctatine / monascorubrin	Polyketide:Iterative type I	8%
Region 84.5	terpene	861,008	882,613	squalestatin S1	Terpene	40%

MCQH01000069 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 87.1	NRPS-like	1,499	24,645
Region 87.2	NRPS-like	483,858	527,178

MCQH01000310 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 88.1	NRPS	1	51,319

MCQH01000140 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 95.1	terpene	515,853	536,812

MCQH01000263 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 96.1	T1PKS	122,217	168,681

MCQH01000138 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 100.1	NRPS	32,787	82,197
Region 100.2	NRPS,T1PKS	101,120	152,971	pyranonigrin E	Polyketide	100%

MCQH01000110 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 102.1	terpene	121,664	139,867

MCQH01000007 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 105.1	NRPS-like	21,033	64,863
Region 105.2	T1PKS	66,126	114,635

MCQH01000073 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 106.1	NRPS,T1PKS	295,663	379,126	fumonisin	Polyketide	47%

MCQH01000216 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 107.1	T1PKS	41,493	89,675

MCQH01000265 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 113.1	T1PKS	8,392	55,712

MCQH01000282 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 117.1	NRPS	85,384	136,831
Region 117.2	NRPS	403,394	462,714	nidulanin A	Polyketide	75%

MCQH01000053 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 128.1	NRPS-like	88,564	132,873

MCQH01000019 (Aspergillus niger)

Region	Type	From	To	Most similar known cluster		Similarity
Region 139.1	T1PKS	311,966	365,782
Region 139.2	T1PKS,NRPS-like	403,146	474,252
Region 139.3	T1PKS	716,331	763,794
Region 139.4	terpene	1,151,343	1,172,464	shearinine D	Terpene	33%

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	NRPS,T1PKS	1	39,373
Region 1.2	T1PKS	320,151	367,973	pyripyropene A	Terpene + Polyketide	25%
Region 1.3	NRPS-like	493,262	536,048
Region 1.4	terpene	699,828	721,143
Region 2.1	indole	356,685	378,135
Region 2.2	bacteriocin	513,777	524,467
Region 2.3	terpene	939,499	960,994
Region 2.4	NRPS,T1PKS	964,901	1,016,922
Region 2.5	T1PKS	1,147,357	1,192,738	TAN-1612 / 1-(2,3,5,10-tetrahydroxy-7-methoxy-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl)pentane-2,4-dione / desmethyl TAN-1612	Polyketide:Iterative type I	100%
Region 13.1	NRPS-like	32,213	75,319
Region 23.1	T1PKS	154,786	198,427
Region 23.2	NRPS	246,718	293,376
Region 23.3	NRPS-like	323,374	366,394
Region 23.4	T1PKS	375,265	421,161	duclauxin	Polyketide	50%
Region 23.5	T1PKS	442,842	491,317
Region 23.6	terpene	526,681	548,296
Region 34.1	NRPS	1,708,161	1,755,237
Region 56.1	T1PKS,NRPS	157,937	210,080	phyllostictine A / phyllostictine B	NRP + Polyketide	20%
Region 56.2	NRPS-like	421,803	465,183
Region 56.3	terpene	552,528	574,528
Region 58.1	NRPS	304,537	348,970
Region 58.2	terpene	473,694	495,391	shearinine D	Terpene	9%
Region 58.3	NRPS,terpene	499,395	546,460
Region 61.1	terpene	61,134	83,690
Region 61.2	NRPS-like	104,680	147,775
Region 62.1	terpene	179,639	200,874
Region 62.2	T1PKS	530,461	571,795
Region 62.3	T1PKS	944,298	988,044
Region 62.4	T1PKS	1,160,304	1,203,858
Region 63.1	T1PKS	116,070	163,561
Region 63.2	terpene	907,330	928,286
Region 64.1	NRPS	241,964	295,201
Region 65.1	siderophore	138,707	150,850
Region 65.2	NRPS-like	161,354	205,839
Region 66.1	NRPS	318,822	377,842
Region 66.2	T3PKS	542,535	583,761
Region 66.3	terpene	696,598	718,921
Region 69.1	NRPS,T1PKS	1	50,437	dihydroisoflavipucine / isoflavipucine	NRP + Polyketide:Iterative type I	12%
Region 69.2	terpene	155,002	177,008
Region 69.3	T1PKS	194,178	238,570
Region 69.4	indole	542,326	563,685
Region 70.1	T1PKS	211,721	257,593
Region 70.2	NRPS,T1PKS	294,162	400,133	azanigerone A	Polyketide	100%
Region 70.3	T1PKS	461,399	506,762	yanuthone D	Polyketide	100%
Region 71.1	NRPS,T1PKS	203,741	274,367	AbT1	NRP	100%
Region 71.2	NRPS-like,T1PKS	316,324	371,653	notoamide A	NRP	11%
Region 72.1	T1PKS	94,885	139,264
Region 72.2	NRPS	141,032	193,111
Region 72.3	T1PKS,NRPS-like	846,882	895,457
Region 73.1	T1PKS,NRPS	722,119	774,080	pyranonigrin E	Polyketide	100%
Region 74.1	T1PKS	1	32,499	naphthopyrone	Polyketide	100%
Region 74.2	terpene	80,467	98,791
Region 74.3	terpene	180,163	202,479	clavaric acid	Terpene	100%
Region 75.1	NRPS-like	2,968	27,539
Region 75.2	terpene	55,641	77,041
Region 75.3	NRPS-like	199,298	242,627
Region 76.1	NRPS	468,273	514,268
Region 76.2	betalactone	874,384	903,492
Region 77.1	T1PKS,NRPS-like	253,287	310,174
Region 78.1	NRPS-like	19,917	63,710
Region 79.1	T1PKS,NRPS	496,071	547,464
Region 79.2	terpene	553,020	565,334
Region 80.1	NRPS	60,091	120,022
Region 81.1	T1PKS	322,303	361,913	aflavarin	Polyketide	60%
Region 81.2	T1PKS	432,388	480,880
Region 84.1	siderophore	299,102	311,168
Region 84.2	NRPS	379,928	434,404
Region 84.3	NRPS,T1PKS	600,981	707,938
Region 84.4	T1PKS	797,634	845,399	ankaflavin / monascin / rubropunctatine / monascorubrin	Polyketide:Iterative type I	8%
Region 84.5	terpene	861,008	882,613	squalestatin S1	Terpene	40%
Region 87.1	NRPS-like	1,499	24,645
Region 87.2	NRPS-like	483,858	527,178
Region 88.1	NRPS	1	51,319
Region 95.1	terpene	515,853	536,812
Region 96.1	T1PKS	122,217	168,681
Region 100.1	NRPS	32,787	82,197
Region 100.2	NRPS,T1PKS	101,120	152,971	pyranonigrin E	Polyketide	100%
Region 102.1	terpene	121,664	139,867
Region 105.1	NRPS-like	21,033	64,863
Region 105.2	T1PKS	66,126	114,635
Region 106.1	NRPS,T1PKS	295,663	379,126	fumonisin	Polyketide	47%
Region 107.1	T1PKS	41,493	89,675
Region 113.1	T1PKS	8,392	55,712
Region 117.1	NRPS	85,384	136,831
Region 117.2	NRPS	403,394	462,714	nidulanin A	Polyketide	75%
Region 128.1	NRPS-like	88,564	132,873
Region 139.1	T1PKS	311,966	365,782
Region 139.2	T1PKS,NRPS-like	403,146	474,252
Region 139.3	T1PKS	716,331	763,794
Region 139.4	terpene	1,151,343	1,172,464	shearinine D	Terpene	33%

No secondary metabolite regions were found in these records:: MCQH01000276 (Aspergillus niger); MCQH01000129 (Aspergillus niger); MCQH01000183 (Aspergillus niger); MCQH01000218 (Aspergillus niger); MCQH01000076 (Aspergillus niger); MCQH01000220 (Aspergillus niger); MCQH01000250 (Aspergillus niger); MCQH01000114 (Aspergillus niger); MCQH01000001 (Aspergillus niger); MCQH01000299 (Aspergillus niger); MCQH01000044 (Aspergillus niger); MCQH01000244 (Aspergillus niger); MCQH01000060 (Aspergillus niger); MCQH01000274 (Aspergillus niger); MCQH01000133 (Aspergillus niger); MCQH01000269 (Aspergillus niger); MCQH01000008 (Aspergillus niger); MCQH01000056 (Aspergillus niger); MCQH01000281 (Aspergillus niger); MCQH01000279 (Aspergillus niger); MCQH01000252 (Aspergillus niger); MCQH01000079 (Aspergillus niger); MCQH01000180 (Aspergillus niger); MCQH01000254 (Aspergillus niger); MCQH01000171 (Aspergillus niger); MCQH01000141 (Aspergillus niger); MCQH01000194 (Aspergillus niger); MCQH01000178 (Aspergillus niger); MCQH01000062 (Aspergillus niger); MCQH01000094 (Aspergillus niger); MCQH01000275 (Aspergillus niger); MCQH01000154 (Aspergillus niger); MCQH01000293 (Aspergillus niger); MCQH01000111 (Aspergillus niger); MCQH01000098 (Aspergillus niger); MCQH01000030 (Aspergillus niger); MCQH01000181 (Aspergillus niger); MCQH01000280 (Aspergillus niger); MCQH01000125 (Aspergillus niger); MCQH01000084 (Aspergillus niger); MCQH01000147 (Aspergillus niger); MCQH01000200 (Aspergillus niger); MCQH01000087 (Aspergillus niger); MCQH01000268 (Aspergillus niger); MCQH01000241 (Aspergillus niger); MCQH01000099 (Aspergillus niger); MCQH01000123 (Aspergillus niger); MCQH01000144 (Aspergillus niger); MCQH01000063 (Aspergillus niger); MCQH01000242 (Aspergillus niger); MCQH01000249 (Aspergillus niger); MCQH01000029 (Aspergillus niger); MCQH01000142 (Aspergillus niger); MCQH01000130 (Aspergillus niger); MCQH01000068 (Aspergillus niger); MCQH01000215 (Aspergillus niger); MCQH01000173 (Aspergillus niger); MCQH01000222 (Aspergillus niger); MCQH01000036 (Aspergillus niger); MCQH01000054 (Aspergillus niger); MCQH01000255 (Aspergillus niger); MCQH01000195 (Aspergillus niger); MCQH01000058 (Aspergillus niger); MCQH01000191 (Aspergillus niger); MCQH01000253 (Aspergillus niger); MCQH01000188 (Aspergillus niger); MCQH01000288 (Aspergillus niger); MCQH01000043 (Aspergillus niger); MCQH01000162 (Aspergillus niger); MCQH01000217 (Aspergillus niger); MCQH01000219 (Aspergillus niger); MCQH01000153 (Aspergillus niger); MCQH01000156 (Aspergillus niger); MCQH01000067 (Aspergillus niger); MCQH01000289 (Aspergillus niger); MCQH01000014 (Aspergillus niger); MCQH01000021 (Aspergillus niger); MCQH01000226 (Aspergillus niger); MCQH01000065 (Aspergillus niger); MCQH01000013 (Aspergillus niger); MCQH01000032 (Aspergillus niger); MCQH01000157 (Aspergillus niger); MCQH01000270 (Aspergillus niger); MCQH01000292 (Aspergillus niger); MCQH01000047 (Aspergillus niger); MCQH01000057 (Aspergillus niger); MCQH01000105 (Aspergillus niger); MCQH01000309 (Aspergillus niger); MCQH01000229 (Aspergillus niger); MCQH01000273 (Aspergillus niger); MCQH01000131 (Aspergillus niger); MCQH01000304 (Aspergillus niger); MCQH01000127 (Aspergillus niger); MCQH01000075 (Aspergillus niger); MCQH01000271 (Aspergillus niger); MCQH01000031 (Aspergillus niger); MCQH01000016 (Aspergillus niger); MCQH01000294 (Aspergillus niger); MCQH01000256 (Aspergillus niger); MCQH01000158 (Aspergillus niger); MCQH01000259 (Aspergillus niger); MCQH01000088 (Aspergillus niger); MCQH01000145 (Aspergillus niger); MCQH01000046 (Aspergillus niger); MCQH01000179 (Aspergillus niger); MCQH01000262 (Aspergillus niger); MCQH01000119 (Aspergillus niger); MCQH01000109 (Aspergillus niger); MCQH01000287 (Aspergillus niger)

Compact view

MCQH01000199 - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 1 - 39,373 nt. (total: 39,373 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 39373:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_008233

Search NORINE for peptide: strict or relaxed

PKS_AT (580..895): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 76.0
Methoxymalonyl-CoA: 65.6
Malonyl-CoA: 48.1
Isobutyryl-CoA: 41.7
Benzoyl-CoA: 34.9
Ethylmalonyl-CoA: 34.5
Propionyl-CoA: 27.1
3-Methylbutyryl-CoA: 19.7
fatty_acid: 15.8
Acetyl-CoA: 15.4
inactive: 15.0
trans-1,2-CPDA: 11.8
CHC-CoA: 9.0
2-Methylbutyryl-CoA: 7.2

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; 2-Methylbutyryl-CoA: 58.3%

AMP-binding (2943..3328): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: daftfvamak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000199 - Region 2 - T1PKS

Download region GenBank file

Location: 320,151 - 367,973 nt. (total: 47,823 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

Similar subclusters

No matches found.

MCQH01000199 - Region 3 - NRPS-like

Download region GenBank file

Location: 493,262 - 536,048 nt. (total: 42,787 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 493261 - 536048:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_008385

Search NORINE for peptide: strict or relaxed

AMP-binding (25..443): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: vgefvggagk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000199 - Region 4 - terpene

Download region GenBank file

Location: 699,828 - 721,143 nt. (total: 21,316 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

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Gene details

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ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000066 - Region 1 - indole

Download region GenBank file

Location: 356,685 - 378,135 nt. (total: 21,451 nt) Show pHMM detection rules used

indole: (indsynth or dmat or indole_PTase)

Legend:

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ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000066 - Region 2 - bacteriocin

Download region GenBank file

Location: 513,777 - 524,467 nt. (total: 10,691 nt) Show pHMM detection rules used

bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

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Gene details

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ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000066 - Region 3 - terpene

Download region GenBank file

Location: 939,499 - 960,994 nt. (total: 21,496 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

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ClusterBlast

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SubClusterBlast

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000066 - Region 4 - NRPS,T1PKS

Download region GenBank file

Location: 964,901 - 1,016,922 nt. (total: 52,022 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 4, location 964900 - 1016922:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_003379

Search NORINE for peptide: strict or relaxed

PKS_AT (551..867): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 59.8
Methoxymalonyl-CoA: 51.2
Propionyl-CoA: 25.8
Malonyl-CoA: 24.8
Ethylmalonyl-CoA: 24.0
Benzoyl-CoA: 24.0
Isobutyryl-CoA: 23.7
fatty_acid: 16.6
inactive: 14.3
trans-1,2-CPDA: 9.9
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

AMP-binding (2936..3338): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: dafllgavak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000066 - Region 5 - T1PKS

Download region GenBank file

Location: 1,147,357 - 1,192,738 nt. (total: 45,382 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 5, location 1147356 - 1192738:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_003449

PKS_AT (925..1226): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 84.2
Methylmalonyl-CoA: 63.9
inactive: 60.0
Methoxymalonyl-CoA: 49.0
Isobutyryl-CoA: 34.2
Acetyl-CoA: 29.0
Ethylmalonyl-CoA: 26.0
Benzoyl-CoA: 24.5
Propionyl-CoA: 22.9
2-Methylbutyryl-CoA: 21.1
fatty_acid: 18.4
3-Methylbutyryl-CoA: 17.9
CHC-CoA: 16.9
trans-1,2-CPDA: 13.1

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 70.8%

MCQH01000172 - Region 1 - NRPS-like

Download region GenBank file

Location: 32,213 - 75,319 nt. (total: 43,107 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 32212 - 75319:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_007083

Search NORINE for peptide: strict or relaxed

AMP-binding (9..431): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: vamflgsagk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000169 - Region 1 - T1PKS

Download region GenBank file

Location: 154,786 - 198,427 nt. (total: 43,642 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000169 - Region 2 - NRPS

Download region GenBank file

Location: 246,718 - 293,376 nt. (total: 46,659 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

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Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 246717 - 293376:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ala - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_006641

Search NORINE for peptide: strict or relaxed

AMP-binding (48..447): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: dasgffipyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1119..1530): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dahnilapik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000169 - Region 3 - NRPS-like

Download region GenBank file

Location: 323,374 - 366,394 nt. (total: 43,021 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 323373 - 366394:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_006671

Search NORINE for peptide: strict or relaxed

AMP-binding (4..407): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: dmfflativk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000169 - Region 4 - T1PKS

Download region GenBank file

Location: 375,265 - 421,161 nt. (total: 45,897 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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resistance

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Gene details

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 4, location 375264 - 421161:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_006693

PKS_AT (923..1222): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 85.9
inactive: 42.8
Methoxymalonyl-CoA: 36.2
Methylmalonyl-CoA: 32.7
Isobutyryl-CoA: 24.7
CHC-CoA: 22.0
2-Methylbutyryl-CoA: 21.7
Propionyl-CoA: 18.2
Ethylmalonyl-CoA: 18.0
Acetyl-CoA: 16.2
Benzoyl-CoA: 15.0
fatty_acid: 13.7
3-Methylbutyryl-CoA: 11.1
trans-1,2-CPDA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%

MCQH01000169 - Region 5 - T1PKS

Download region GenBank file

Location: 442,842 - 491,317 nt. (total: 48,476 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 5, location 442841 - 491317:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_006716

PKS_AT (584..913): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 70.7
Malonyl-CoA: 63.8
Methoxymalonyl-CoA: 59.7
Isobutyryl-CoA: 48.8
Ethylmalonyl-CoA: 35.9
Benzoyl-CoA: 31.6
fatty_acid: 28.5
inactive: 17.1
Acetyl-CoA: 12.8
CHC-CoA: 12.6
trans-1,2-CPDA: 11.7
2-Methylbutyryl-CoA: 11.0
Propionyl-CoA: 10.4
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

MCQH01000169 - Region 6 - terpene

Download region GenBank file

Location: 526,681 - 548,296 nt. (total: 21,616 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

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ClusterBlast

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SubClusterBlast

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000231 - Region 1 - NRPS

Download region GenBank file

Location: 1,708,161 - 1,755,237 nt. (total: 47,077 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 1708160 - 1755237:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_010524

Search NORINE for peptide: strict or relaxed

AMP-binding (290..669): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: sardvgsqlk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1313..1697): X

NRPSPredictor2: phe, trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: phe, trp
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dgfcagaick
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000306 - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 157,937 - 210,080 nt. (total: 52,144 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 157936 - 210080:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - gln)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_011698

Search NORINE for peptide: strict or relaxed

PKS_AT (550..868): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 76.3
Methoxymalonyl-CoA: 61.9
Ethylmalonyl-CoA: 55.9
Malonyl-CoA: 37.3
Isobutyryl-CoA: 34.7
Benzoyl-CoA: 28.7
Propionyl-CoA: 23.5
fatty_acid: 22.5
trans-1,2-CPDA: 20.4
Acetyl-CoA: 14.5
CHC-CoA: 12.1
3-Methylbutyryl-CoA: 10.1
inactive: 0.0
2-Methylbutyryl-CoA: -1.3

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 58.3%

AMP-binding (2993..3402): gln

NRPSPredictor2: gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: gln

Stachelhaus prediction details:

Stachelhaus sequence:: nhdkfgsisk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000306 - Region 2 - NRPS-like

Download region GenBank file

Location: 421,803 - 465,183 nt. (total: 43,381 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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Gene details

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 421802 - 465183:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_011783

Search NORINE for peptide: strict or relaxed

AMP-binding (23..349): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: aayldcc--k
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000306 - Region 3 - terpene

Download region GenBank file

Location: 552,528 - 574,528 nt. (total: 22,001 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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resistance

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Gene details

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ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000015 - Region 1 - NRPS

Download region GenBank file

Location: 304,537 - 348,970 nt. (total: 44,434 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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other genes

resistance

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Gene details

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 304536 - 348970:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_000656

Search NORINE for peptide: strict or relaxed

AMP-binding (216..620): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvdggggigk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000015 - Region 2 - terpene

Download region GenBank file

Location: 473,694 - 495,391 nt. (total: 21,698 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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ClusterBlast

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Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

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No matches found.

MCQH01000015 - Region 3 - NRPS,terpene

Download region GenBank file

Location: 499,395 - 546,460 nt. (total: 47,066 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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NRPS/PKS domains

ClusterBlast

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Detailed domain annotation

Selected features only

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Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 499394 - 546460:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (leu - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 499394 - 546201:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (leu - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_000725

Search NORINE for peptide: strict or relaxed

AMP-binding (34..430): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: dalfigavak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1152..1554): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: digsvamiyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000072 - Region 1 - terpene

Download region GenBank file

Location: 61,134 - 83,690 nt. (total: 22,557 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000072 - Region 2 - NRPS-like

Download region GenBank file

Location: 104,680 - 147,775 nt. (total: 43,096 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 104679 - 147775:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_004044

Search NORINE for peptide: strict or relaxed

AMP-binding (25..424): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dtvqiggvyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000184 - Region 1 - terpene

Download region GenBank file

Location: 179,639 - 200,874 nt. (total: 21,236 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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ClusterBlast

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No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000184 - Region 2 - T1PKS

Download region GenBank file

Location: 530,461 - 571,795 nt. (total: 41,335 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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ClusterBlast

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Detailed domain annotation

Selected features only

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Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 530460 - 571795:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_007506

PKS_AT (592..917): pk

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 75.8
Methylmalonyl-CoA: 68.4
Malonyl-CoA: 59.6
Isobutyryl-CoA: 43.3
Propionyl-CoA: 36.5
Ethylmalonyl-CoA: 31.9
inactive: 21.9
fatty_acid: 21.5
Benzoyl-CoA: 19.7
3-Methylbutyryl-CoA: 18.4
CHC-CoA: 17.5
trans-1,2-CPDA: 15.4
2-Methylbutyryl-CoA: 14.4
Acetyl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 66.7%; 2-Methylbutyryl-CoA: 58.3%

MCQH01000184 - Region 3 - T1PKS

Download region GenBank file

Location: 944,298 - 988,044 nt. (total: 43,747 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

ClusterBlast

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Detailed domain annotation

Selected features only

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Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 944297 - 988044:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_007647

PKS_AT (631..951): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 66.3
Malonyl-CoA: 63.1
Methoxymalonyl-CoA: 54.1
Ethylmalonyl-CoA: 38.7
Isobutyryl-CoA: 28.5
2-Methylbutyryl-CoA: 18.7
Propionyl-CoA: 18.2
trans-1,2-CPDA: 17.4
inactive: 17.3
Benzoyl-CoA: 15.2
CHC-CoA: 15.1
fatty_acid: 7.5
Acetyl-CoA: 1.4
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

MCQH01000184 - Region 4 - T1PKS

Download region GenBank file

Location: 1,160,304 - 1,203,858 nt. (total: 43,555 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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NRPS/PKS domains

ClusterBlast

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Detailed domain annotation

Selected features only

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Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000164 - Region 1 - T1PKS

Download region GenBank file

Location: 116,070 - 163,561 nt. (total: 47,492 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

ClusterBlast

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Detailed domain annotation

Selected features only

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Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 116069 - 163561:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_005909

Search NORINE for peptide: strict or relaxed

AMP-binding (30..421): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gawfgsspvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_005910

PKS_AT (552..862): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 90.4
Ethylmalonyl-CoA: 85.2
Methoxymalonyl-CoA: 82.4
Malonyl-CoA: 64.2
Isobutyryl-CoA: 60.2
Benzoyl-CoA: 33.9
Propionyl-CoA: 31.4
2-Methylbutyryl-CoA: 23.1
CHC-CoA: 21.8
fatty_acid: 17.5
trans-1,2-CPDA: 17.2
3-Methylbutyryl-CoA: 11.4
inactive: 9.8
Acetyl-CoA: 4.9

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methoxymalonyl-CoA: 58.3%; Methylmalonyl-CoA: 58.3%

MCQH01000164 - Region 2 - terpene

Download region GenBank file

Location: 907,330 - 928,286 nt. (total: 20,957 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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ClusterBlast

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No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000074 - Region 1 - NRPS

Download region GenBank file

Location: 241,964 - 295,201 nt. (total: 53,238 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

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Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000209 - Region 1 - siderophore

Download region GenBank file

Location: 138,707 - 150,850 nt. (total: 12,144 nt) Show pHMM detection rules used

siderophore: IucA_IucC

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No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000209 - Region 2 - NRPS-like

Download region GenBank file

Location: 161,354 - 205,839 nt. (total: 44,486 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

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Detailed domain annotation

Selected features only

Show module domains

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Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 161353 - 205839:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_009282

Search NORINE for peptide: strict or relaxed

AMP-binding (268..736): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dprhfvmrak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000246 - Region 1 - NRPS

Download region GenBank file

Location: 318,822 - 377,842 nt. (total: 59,021 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 318821 - 377842:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - pro - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_010847

Search NORINE for peptide: strict or relaxed

AMP-binding (48..471): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gllhiasptk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_010848

Search NORINE for peptide: strict or relaxed

AMP-binding (238..683): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dpamwitiak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1396..1805): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: dvqhtitvvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2521..2926): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dplstgaigk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000246 - Region 2 - T3PKS

Download region GenBank file

Location: 542,535 - 583,761 nt. (total: 41,227 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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No matches found.

MCQH01000246 - Region 3 - terpene

Download region GenBank file

Location: 696,598 - 718,921 nt. (total: 22,324 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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No matches found.

Similar subclusters

No matches found.

MCQH01000170 - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 1 - 50,437 nt. (total: 50,437 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

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Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 50437:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_006836

Search NORINE for peptide: strict or relaxed

PKS_AT (568..884): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 66.7
Methoxymalonyl-CoA: 59.4
Ethylmalonyl-CoA: 38.6
Propionyl-CoA: 31.7
Isobutyryl-CoA: 23.0
Benzoyl-CoA: 20.1
3-Methylbutyryl-CoA: 14.0
2-Methylbutyryl-CoA: 13.6
fatty_acid: 13.3
inactive: 11.2
Malonyl-CoA: 10.7
trans-1,2-CPDA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 66.7%; 2-Methylbutyryl-CoA: 58.3%

AMP-binding (2826..3235): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: daalmgavak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_006840

Search NORINE for peptide: strict or relaxed

AMP-binding (29..466): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gllvigcpik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000170 - Region 2 - terpene

Download region GenBank file

Location: 155,002 - 177,008 nt. (total: 22,007 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

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No matches found.

Similar subclusters

No matches found.

MCQH01000170 - Region 3 - T1PKS

Download region GenBank file

Location: 194,178 - 238,570 nt. (total: 44,393 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

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Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000170 - Region 4 - indole

Download region GenBank file

Location: 542,326 - 563,685 nt. (total: 21,360 nt) Show pHMM detection rules used

indole: (indsynth or dmat or indole_PTase)

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Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000155 - Region 1 - T1PKS

Download region GenBank file

Location: 211,721 - 257,593 nt. (total: 45,873 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

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SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 211720 - 257593:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-redmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_005604

PKS_AT (517..822): mmal

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 78.6
Methoxymalonyl-CoA: 68.2
Malonyl-CoA: 55.8
Isobutyryl-CoA: 48.7
Ethylmalonyl-CoA: 47.2
Propionyl-CoA: 40.3
trans-1,2-CPDA: 29.2
Benzoyl-CoA: 28.4
fatty_acid: 20.5
2-Methylbutyryl-CoA: 18.6
Acetyl-CoA: 13.9
CHC-CoA: 13.3
3-Methylbutyryl-CoA: 9.0
inactive: 0.0

ATSignature: Methylmalonyl-CoA, Malonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 70.8%; Malonyl-CoA: 70.8%; Ethylmalonyl-CoA: 62.5%

MCQH01000155 - Region 2 - NRPS,T1PKS

Download region GenBank file

Location: 294,162 - 400,133 nt. (total: 105,972 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

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Similar known gene clusters

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No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 294161 - 400133:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - D-X) + (pk) + (redmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 294161 - 343402:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - D-X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 339273 - 400133:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (redmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_005634

Search NORINE for peptide: strict or relaxed

AMP-binding (241..636): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvlfvggvak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1748..2143): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvlfvggvak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_005638

PKS_AT (1687..1944): pk

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: (unknown)

No matches above 50%

ATCC10864_005644

Search NORINE for peptide: strict or relaxed

AMP-binding (21..441): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: aasargvcik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_005648

PKS_AT (900..1196): pk

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 63.0
Malonyl-CoA: 53.8
Methylmalonyl-CoA: 52.3
inactive: 44.7
Ethylmalonyl-CoA: 23.8
trans-1,2-CPDA: 23.6
Propionyl-CoA: 22.5
CHC-CoA: 21.7
Isobutyryl-CoA: 18.0
2-Methylbutyryl-CoA: 16.5
Benzoyl-CoA: 14.2
3-Methylbutyryl-CoA: 13.6
Acetyl-CoA: 11.0
fatty_acid: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Ethylmalonyl-CoA: 54.2%; inactive: 54.2%

ATCC10864_005655

PKS_AT (579..901): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 90.9
Methylmalonyl-CoA: 66.1
Methoxymalonyl-CoA: 65.2
Isobutyryl-CoA: 29.8
Benzoyl-CoA: 22.3
inactive: 22.1
trans-1,2-CPDA: 17.0
fatty_acid: 16.3
CHC-CoA: 16.2
Propionyl-CoA: 15.7
2-Methylbutyryl-CoA: 14.7
Ethylmalonyl-CoA: 5.9
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Methylmalonyl-CoA: 62.5%; Isobutyryl-CoA: 54.2%

MCQH01000155 - Region 3 - T1PKS

Download region GenBank file

Location: 461,399 - 506,762 nt. (total: 45,364 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 5, location 461398 - 506762:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-ccmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_005692

PKS_AT (594..885): mmal

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 111.9
Ethylmalonyl-CoA: 94.8
Methoxymalonyl-CoA: 91.0
Isobutyryl-CoA: 67.1
Malonyl-CoA: 58.2
trans-1,2-CPDA: 46.4
Benzoyl-CoA: 44.0
Propionyl-CoA: 40.9
2-Methylbutyryl-CoA: 40.5
Acetyl-CoA: 31.8
fatty_acid: 30.0
CHC-CoA: 16.5
3-Methylbutyryl-CoA: 16.1
inactive: 10.4

ATSignature: Methylmalonyl-CoA, Malonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 75.0%; Malonyl-CoA: 75.0%; Ethylmalonyl-CoA: 70.8%

MCQH01000051 - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 203,741 - 274,367 nt. (total: 70,627 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

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Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 203740 - 274367:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (phe) + (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_002407

Search NORINE for peptide: strict or relaxed

AMP-binding (264..666): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: dawmfaatfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_002413

Search NORINE for peptide: strict or relaxed

PKS_AT (547..865): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 76.5
Methoxymalonyl-CoA: 69.0
Ethylmalonyl-CoA: 43.4
Malonyl-CoA: 38.3
Propionyl-CoA: 33.8
Benzoyl-CoA: 27.6
trans-1,2-CPDA: 26.0
Isobutyryl-CoA: 24.4
fatty_acid: 19.2
CHC-CoA: 11.8
2-Methylbutyryl-CoA: 2.6
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 62.5%

AMP-binding (2970..3380): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: didmngcvwk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000051 - Region 2 - NRPS-like,T1PKS

Download region GenBank file

Location: 316,324 - 371,653 nt. (total: 55,330 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 316323 - 371653:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 316323 - 359615:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 324602 - 371653:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_002445

Search NORINE for peptide: strict or relaxed

AMP-binding (29..418): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: hllmyavlik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_002448

PKS_AT (540..849): pk

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 73.2
Methylmalonyl-CoA: 72.4
Malonyl-CoA: 64.7
Ethylmalonyl-CoA: 50.6
Isobutyryl-CoA: 43.7
Propionyl-CoA: 43.3
inactive: 25.0
2-Methylbutyryl-CoA: 24.2
trans-1,2-CPDA: 20.0
Benzoyl-CoA: 14.9
CHC-CoA: 12.4
fatty_acid: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; Methylmalonyl-CoA: 70.8%; Ethylmalonyl-CoA: 62.5%

MCQH01000048 - Region 1 - T1PKS

Download region GenBank file

Location: 94,885 - 139,264 nt. (total: 44,380 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

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regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 94884 - 139264:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_002040

PKS_AT (555..863): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 92.0
Methoxymalonyl-CoA: 89.2
Malonyl-CoA: 87.1
Isobutyryl-CoA: 75.0
Ethylmalonyl-CoA: 66.3
Benzoyl-CoA: 40.2
Propionyl-CoA: 35.2
2-Methylbutyryl-CoA: 30.9
trans-1,2-CPDA: 29.2
inactive: 28.8
Acetyl-CoA: 25.0
fatty_acid: 15.6
CHC-CoA: 13.5
3-Methylbutyryl-CoA: 10.6

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 62.5%

MCQH01000048 - Region 2 - NRPS

Download region GenBank file

Location: 141,032 - 193,111 nt. (total: 52,080 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 141031 - 193111:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_002058

Search NORINE for peptide: strict or relaxed

AMP-binding (449..855): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dianmgnfvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1537..1938): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dawlvgavik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3078..3489): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dagsvggiek
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000048 - Region 3 - NRPS-like,T1PKS

Download region GenBank file

Location: 846,882 - 895,457 nt. (total: 48,576 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 846881 - 895457:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_002297

Search NORINE for peptide: strict or relaxed

AMP-binding (24..423): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dmfvvglask
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

PKS_AT (1161..1455): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 162.6
inactive: 74.8
Methoxymalonyl-CoA: 73.9
Methylmalonyl-CoA: 66.3
Isobutyryl-CoA: 42.7
Propionyl-CoA: 37.3
Acetyl-CoA: 31.3
Ethylmalonyl-CoA: 30.8
Benzoyl-CoA: 29.8
trans-1,2-CPDA: 28.8
CHC-CoA: 27.6
fatty_acid: 18.8
2-Methylbutyryl-CoA: 17.4
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; inactive: 66.7%; Methylmalonyl-CoA: 58.3%

MCQH01000166 - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 722,119 - 774,080 nt. (total: 51,962 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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resistance

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Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 722118 - 774080:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (redmal - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_006527

Search NORINE for peptide: strict or relaxed

PKS_AT (573..889): mal

minowa: Isobutyryl-CoA

Prediction, score:

Isobutyryl-CoA: 77.4
Methylmalonyl-CoA: 76.9
Methoxymalonyl-CoA: 69.4
Malonyl-CoA: 62.0
Ethylmalonyl-CoA: 41.3
Propionyl-CoA: 33.7
inactive: 30.4
3-Methylbutyryl-CoA: 29.7
2-Methylbutyryl-CoA: 27.8
Benzoyl-CoA: 24.2
trans-1,2-CPDA: 21.6
Acetyl-CoA: 13.8
CHC-CoA: 12.1
fatty_acid: 11.4

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; inactive: 58.3%

AMP-binding (2865..3274): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dlgylccvqk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000208 - Region 1 - T1PKS

Download region GenBank file

Location: 1 - 32,499 nt. (total: 32,499 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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other genes

resistance

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Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 32499:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_009036

PKS_AT (912..1211): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 110.5
inactive: 48.6
Methoxymalonyl-CoA: 48.3
Methylmalonyl-CoA: 44.4
Propionyl-CoA: 19.9
Benzoyl-CoA: 17.2
2-Methylbutyryl-CoA: 15.8
Ethylmalonyl-CoA: 13.2
Isobutyryl-CoA: 12.5
CHC-CoA: 11.2
fatty_acid: 10.4
trans-1,2-CPDA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; Methylmalonyl-CoA: 62.5%; Isobutyryl-CoA: 58.3%

MCQH01000208 - Region 2 - terpene

Download region GenBank file

Location: 80,467 - 98,791 nt. (total: 18,325 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000208 - Region 3 - terpene

Download region GenBank file

Location: 180,163 - 202,479 nt. (total: 22,317 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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Select a gene to view the details available for it

ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

Similar subclusters

No matches found.

MCQH01000210 - Region 1 - NRPS-like

Download region GenBank file

Location: 2,968 - 27,539 nt. (total: 24,572 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 2967 - 27539:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_009328

Search NORINE for peptide: strict or relaxed

AMP-binding (69..458): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: hlvicgavik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000210 - Region 2 - terpene

Download region GenBank file

Location: 55,641 - 77,041 nt. (total: 21,401 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000210 - Region 3 - NRPS-like

Download region GenBank file

Location: 199,298 - 242,627 nt. (total: 43,330 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

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other genes

resistance

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Gene details

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 199297 - 242627:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_009403

Search NORINE for peptide: strict or relaxed

AMP-binding (20..423): X

NRPSPredictor2: phe, trp, phg, tyr, bht

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: hmllygaiik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000027 - Region 1 - NRPS

Download region GenBank file

Location: 468,273 - 514,268 nt. (total: 45,996 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

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other genes

resistance

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Gene details

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 468272 - 514268:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_001462

Search NORINE for peptide: strict or relaxed

AMP-binding (222..614): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvlevgavvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000027 - Region 2 - betalactone

Download region GenBank file

Location: 874,384 - 903,492 nt. (total: 29,109 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

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ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000240 - Region 1 - NRPS-like,T1PKS

Download region GenBank file

Location: 253,287 - 310,174 nt. (total: 56,888 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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Gene details

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 253286 - 310174:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 253286 - 300730:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 267117 - 310174:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_010627

Search NORINE for peptide: strict or relaxed

AMP-binding (83..492): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: fswygavvfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_010628

PKS_AT (547..861): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 64.3
Methoxymalonyl-CoA: 58.3
Ethylmalonyl-CoA: 47.4
Isobutyryl-CoA: 37.7
Malonyl-CoA: 35.0
trans-1,2-CPDA: 25.0
Benzoyl-CoA: 24.6
fatty_acid: 16.8
CHC-CoA: 14.2
2-Methylbutyryl-CoA: 13.1
Propionyl-CoA: 8.7
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

ATCC10864_010631

Search NORINE for peptide: strict or relaxed

AMP-binding (7..412): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dmcivggifk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000245 - Region 1 - NRPS-like

Download region GenBank file

Location: 19,917 - 63,710 nt. (total: 43,794 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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resistance

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Gene details

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 19916 - 63710:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_010681

Search NORINE for peptide: strict or relaxed

AMP-binding (62..359): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: hasymgh--k
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000204 - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 496,071 - 547,464 nt. (total: 51,394 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 496070 - 547464:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_009022

Search NORINE for peptide: strict or relaxed

PKS_AT (545..858): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 90.8
Methoxymalonyl-CoA: 77.4
Ethylmalonyl-CoA: 60.9
Isobutyryl-CoA: 50.0
Benzoyl-CoA: 49.0
trans-1,2-CPDA: 44.9
Malonyl-CoA: 40.7
inactive: 32.2
Propionyl-CoA: 32.1
2-Methylbutyryl-CoA: 21.9
CHC-CoA: 14.8
fatty_acid: 14.6
Acetyl-CoA: 8.9
3-Methylbutyryl-CoA: 1.8

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 70.8%; Ethylmalonyl-CoA: 58.3%

AMP-binding (3016..3425): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gltllalfgk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000204 - Region 2 - terpene

Download region GenBank file

Location: 553,020 - 565,334 nt. (total: 12,315 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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resistance

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Gene details

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ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000009 - Region 1 - NRPS

Download region GenBank file

Location: 60,091 - 120,022 nt. (total: 59,932 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 60090 - 120022:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_000452

Search NORINE for peptide: strict or relaxed

AMP-binding (22..343): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: ----liaglk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_000458

Search NORINE for peptide: strict or relaxed

AMP-binding (532..913): X

NRPSPredictor2: hydrophobic-aromatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dghiyvmcgk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000196 - Region 1 - T1PKS

Download region GenBank file

Location: 322,303 - 361,913 nt. (total: 39,611 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 322302 - 361913:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_008164

PKS_AT (915..1214): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 71.5
inactive: 51.9
Methoxymalonyl-CoA: 45.1
Methylmalonyl-CoA: 40.2
2-Methylbutyryl-CoA: 19.3
Propionyl-CoA: 18.2
Isobutyryl-CoA: 14.2
Ethylmalonyl-CoA: 13.9
fatty_acid: 12.7
CHC-CoA: 12.4
trans-1,2-CPDA: 11.9
3-Methylbutyryl-CoA: 10.6
Benzoyl-CoA: 9.8
Acetyl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%

MCQH01000196 - Region 2 - T1PKS

Download region GenBank file

Location: 432,388 - 480,880 nt. (total: 48,493 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 432387 - 480880:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (redmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_008208

PKS_AT (577..922): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 92.1
Methoxymalonyl-CoA: 78.8
Methylmalonyl-CoA: 78.2
Isobutyryl-CoA: 56.8
Ethylmalonyl-CoA: 49.9
inactive: 41.9
Propionyl-CoA: 39.1
Benzoyl-CoA: 29.8
2-Methylbutyryl-CoA: 20.4
Acetyl-CoA: 16.4
fatty_acid: 16.3
trans-1,2-CPDA: 15.9
3-Methylbutyryl-CoA: 10.3
CHC-CoA: 7.7

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; inactive: 54.2%

MCQH01000006 - Region 1 - siderophore

Download region GenBank file

Location: 299,102 - 311,168 nt. (total: 12,067 nt) Show pHMM detection rules used

siderophore: IucA_IucC

Legend:

core biosynthetic genes

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Gene details

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ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000006 - Region 2 - NRPS

Download region GenBank file

Location: 379,928 - 434,404 nt. (total: 54,477 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 379927 - 434404:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - pro - X - D-X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_000150

Search NORINE for peptide: strict or relaxed

AMP-binding (225..634): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvlfaggvak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1784..2182): pro

NRPSPredictor2: pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: pro, pip
Small clusters prediction:: pro
Single AA prediction:: pro

Stachelhaus prediction details:

Stachelhaus sequence:: dtqhfasvak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2877..3274): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvsfagsiwk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3957..4353): X

NRPSPredictor2: gly, ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: digsvgiiyk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000006 - Region 3 - NRPS,T1PKS

Download region GenBank file

Location: 600,981 - 707,938 nt. (total: 106,958 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 3, location 600980 - 707938:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - D-X - X) + (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 600980 - 677787:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - D-X - X) + (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 5, location 640408 - 707938:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_000226

Search NORINE for peptide: strict or relaxed

AMP-binding (224..616): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dmlicgfink
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1326..1716): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: daamaigimk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2500..2894): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: damfgglivk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4046..4443): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dawfvgailk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_000235

Search NORINE for peptide: strict or relaxed

AMP-binding (20..455): X

NRPSPredictor2: phe, trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: phe, trp
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: vlmvislfck
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_000237

PKS_AT (539..859): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 87.3
Methoxymalonyl-CoA: 76.8
Isobutyryl-CoA: 60.7
Ethylmalonyl-CoA: 49.9
Malonyl-CoA: 49.1
fatty_acid: 26.9
Propionyl-CoA: 26.1
Benzoyl-CoA: 22.4
inactive: 14.8
trans-1,2-CPDA: 13.5
2-Methylbutyryl-CoA: 11.6
3-Methylbutyryl-CoA: 9.5
CHC-CoA: 8.3
Acetyl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 66.7%

ATCC10864_000242

PKS_AT (548..846): mmal

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 87.4
Malonyl-CoA: 78.9
Methoxymalonyl-CoA: 73.7
Isobutyryl-CoA: 59.8
Ethylmalonyl-CoA: 58.5
Benzoyl-CoA: 43.6
Propionyl-CoA: 42.2
2-Methylbutyryl-CoA: 24.3
trans-1,2-CPDA: 23.2
fatty_acid: 23.2
Acetyl-CoA: 15.7
CHC-CoA: 12.3
inactive: 11.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Methylmalonyl-CoA, Malonyl-CoA

Top 3 matches:: Methylmalonyl-CoA: 75.0%; Malonyl-CoA: 75.0%; Isobutyryl-CoA: 62.5%

MCQH01000006 - Region 4 - T1PKS

Download region GenBank file

Location: 797,634 - 845,399 nt. (total: 47,766 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 6, location 797633 - 845399:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_000297

PKS_AT (924..1219): mal

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 73.3
Methoxymalonyl-CoA: 62.0
Methylmalonyl-CoA: 56.1
inactive: 52.3
Propionyl-CoA: 32.7
Ethylmalonyl-CoA: 29.7
2-Methylbutyryl-CoA: 28.9
CHC-CoA: 26.4
Isobutyryl-CoA: 21.7
trans-1,2-CPDA: 19.1
Benzoyl-CoA: 19.1
fatty_acid: 17.4
3-Methylbutyryl-CoA: 9.5
Acetyl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; inactive: 58.3%; Methylmalonyl-CoA: 54.2%

ATCC10864_000301

PKS_AT (1683..1876): pk

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: (unknown)

No matches above 50%

MCQH01000006 - Region 5 - terpene

Download region GenBank file

Location: 861,008 - 882,613 nt. (total: 21,606 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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ClusterBlast

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Similar gene clusters

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No matches found.

MCQH01000069 - Region 1 - NRPS-like

Download region GenBank file

Location: 1,499 - 24,645 nt. (total: 23,147 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 1498 - 24645:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_003823

Search NORINE for peptide: strict or relaxed

AMP-binding (6..406): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: dlfflgttlk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000069 - Region 2 - NRPS-like

Download region GenBank file

Location: 483,858 - 527,178 nt. (total: 43,321 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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resistance

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 483857 - 527178:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_003981

Search NORINE for peptide: strict or relaxed

AMP-binding (69..353): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: hlsq--t--k
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000310 - Region 1 - NRPS

Download region GenBank file

Location: 1 - 51,319 nt. (total: 51,319 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 51319:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (leu - ala - D-X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_011844

Search NORINE for peptide: strict or relaxed

AMP-binding (40..446): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: dvsdvgpptk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1698..2093): X

NRPSPredictor2: orn, lys, arg

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvsdvgpptk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3245..3649): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: dvcihiltfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4334..4736): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvadtgsptk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (5884..6281): X

NRPSPredictor2: orn, lys, arg

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: orn, lys, arg
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvsdvgpptk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000140 - Region 1 - terpene

Download region GenBank file

Location: 515,853 - 536,812 nt. (total: 20,960 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000263 - Region 1 - T1PKS

Download region GenBank file

Location: 122,217 - 168,681 nt. (total: 46,465 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 122216 - 168681:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_011216

PKS_AT (904..1193): pk

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 54.9
Malonyl-CoA: 51.1
Methylmalonyl-CoA: 48.9
inactive: 43.0
Ethylmalonyl-CoA: 36.3
Propionyl-CoA: 27.4
CHC-CoA: 27.2
Acetyl-CoA: 25.9
fatty_acid: 23.0
2-Methylbutyryl-CoA: 20.6
trans-1,2-CPDA: 20.3
Benzoyl-CoA: 16.3
Isobutyryl-CoA: 16.2
3-Methylbutyryl-CoA: 11.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; Ethylmalonyl-CoA: 54.2%; inactive: 54.2%

MCQH01000138 - Region 1 - NRPS

Download region GenBank file

Location: 32,787 - 82,197 nt. (total: 49,411 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

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resistance

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Gene details

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 32786 - 82197:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_005003

Search NORINE for peptide: strict or relaxed

AMP-binding (238..633): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: vmaivavgak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1395..1801): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dmwmfaavlk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2480..2852): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dawfvgt--k
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000138 - Region 2 - NRPS,T1PKS

Download region GenBank file

Location: 101,120 - 152,971 nt. (total: 51,852 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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Gene details

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NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 101119 - 152971:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_005023

Search NORINE for peptide: strict or relaxed

PKS_AT (566..879): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 88.5
Methoxymalonyl-CoA: 85.2
Isobutyryl-CoA: 79.1
Malonyl-CoA: 68.2
Ethylmalonyl-CoA: 47.5
Propionyl-CoA: 45.7
Benzoyl-CoA: 39.1
inactive: 38.5
3-Methylbutyryl-CoA: 30.4
trans-1,2-CPDA: 26.0
2-Methylbutyryl-CoA: 24.2
Acetyl-CoA: 23.4
CHC-CoA: 11.7
fatty_acid: 10.7

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 62.5%; Isobutyryl-CoA: 54.2%

AMP-binding (2856..3269): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dlvylatvqk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000110 - Region 1 - terpene

Download region GenBank file

Location: 121,664 - 139,867 nt. (total: 18,204 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

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resistance

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ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000007 - Region 1 - NRPS-like

Download region GenBank file

Location: 21,033 - 64,863 nt. (total: 43,831 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 21032 - 64863:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (ala)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_000389

Search NORINE for peptide: strict or relaxed

AMP-binding (13..412): ala

NRPSPredictor2: ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: ala

Stachelhaus prediction details:

Stachelhaus sequence:: nvwlwnceik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000007 - Region 2 - T1PKS

Download region GenBank file

Location: 66,126 - 114,635 nt. (total: 48,510 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

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regulatory genes

other genes

resistance

reset view

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 66125 - 114635:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_000409

PKS_AT (553..868): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 75.9
Methoxymalonyl-CoA: 64.9
Malonyl-CoA: 56.3
Isobutyryl-CoA: 44.4
Ethylmalonyl-CoA: 33.1
Propionyl-CoA: 27.4
2-Methylbutyryl-CoA: 14.7
Benzoyl-CoA: 12.4
trans-1,2-CPDA: 12.1
fatty_acid: 11.8
inactive: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 70.8%; Ethylmalonyl-CoA: 66.7%

MCQH01000073 - Region 1 - NRPS,T1PKS

Download region GenBank file

Location: 295,663 - 379,126 nt. (total: 83,464 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

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other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 295662 - 379126:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 295662 - 347583:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 320066 - 379126:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_004325

Search NORINE for peptide: strict or relaxed

AMP-binding (24..432): X

NRPSPredictor2: asp, asn, glu, gln, aad

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: iighrgvpak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_004334

PKS_AT (582..886): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 94.2
Methoxymalonyl-CoA: 79.4
Malonyl-CoA: 62.9
Ethylmalonyl-CoA: 57.9
Isobutyryl-CoA: 50.1
Propionyl-CoA: 46.8
Benzoyl-CoA: 39.8
fatty_acid: 36.8
trans-1,2-CPDA: 31.8
2-Methylbutyryl-CoA: 21.9
CHC-CoA: 19.8
3-Methylbutyryl-CoA: 11.9
Acetyl-CoA: 5.5
inactive: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Propionyl-CoA: 62.5%; 2-Methylbutyryl-CoA: 62.5%

ATCC10864_004336

PKS_AT (544..856): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 68.5
Malonyl-CoA: 52.9
Methoxymalonyl-CoA: 52.5
3-Methylbutyryl-CoA: 32.3
Ethylmalonyl-CoA: 31.0
Propionyl-CoA: 24.9
Benzoyl-CoA: 21.9
Acetyl-CoA: 21.4
CHC-CoA: 21.1
fatty_acid: 18.4
2-Methylbutyryl-CoA: 17.4
Isobutyryl-CoA: 17.3
trans-1,2-CPDA: 15.2
inactive: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; CE-Malonyl-CoA: 62.5%; Methylmalonyl-CoA: 62.5%

MCQH01000216 - Region 1 - T1PKS

Download region GenBank file

Location: 41,493 - 89,675 nt. (total: 48,183 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

MCQH01000265 - Region 1 - T1PKS

Download region GenBank file

Location: 8,392 - 55,712 nt. (total: 47,321 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 8391 - 55712:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_011241

PKS_AT (560..871): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 54.1
Methoxymalonyl-CoA: 53.7
Isobutyryl-CoA: 45.4
Malonyl-CoA: 39.4
inactive: 29.9
Propionyl-CoA: 25.3
Ethylmalonyl-CoA: 19.9
trans-1,2-CPDA: 16.2
Acetyl-CoA: 13.9
fatty_acid: 12.2
CHC-CoA: 12.2
Benzoyl-CoA: 10.5
2-Methylbutyryl-CoA: 7.2
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Isobutyryl-CoA: 62.5%; Methylmalonyl-CoA: 62.5%

MCQH01000282 - Region 1 - NRPS

Download region GenBank file

Location: 85,384 - 136,831 nt. (total: 51,448 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 85383 - 136831:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X - X - leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_011365

Search NORINE for peptide: strict or relaxed

AMP-binding (234..634): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: tmyvaggalk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1343..1742): X

NRPSPredictor2: gly, ala, val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dfiivgapik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2433..2830): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dlyiiglqck
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3523..3921): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: davviaamvk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (4640..5035): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: N/A
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: dailvgaqik
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000282 - Region 2 - NRPS

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Location: 403,394 - 462,714 nt. (total: 59,321 nt) Show pHMM detection rules used

NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 403393 - 462714:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - D-X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_011472

Search NORINE for peptide: strict or relaxed

AMP-binding (254..652): X

NRPSPredictor2: phe, trp, phg, tyr, bht

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: daviiaavak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (1797..2197): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dmqsvafssk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (2839..3243): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: dvlstgavak
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

AMP-binding (3930..4331): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: damfvggifk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000053 - Region 1 - NRPS-like

Download region GenBank file

Location: 88,564 - 132,873 nt. (total: 44,310 nt) Show pHMM detection rules used

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 88563 - 132873:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 88563 - 127498:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 90206 - 132873:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_002532

Search NORINE for peptide: strict or relaxed

AMP-binding (59..465): X

NRPSPredictor2: hydrophilic

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: vaefnggagk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_002534

Search NORINE for peptide: strict or relaxed

AMP-binding (239..634): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: dlvftgsmfk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000019 - Region 1 - T1PKS

Download region GenBank file

Location: 311,966 - 365,782 nt. (total: 53,817 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 311965 - 365782:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_000901

Search NORINE for peptide: strict or relaxed

AMP-binding (113..568): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: efevmggamk
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

ATCC10864_000905

PKS_AT (592..914): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 60.2
Methoxymalonyl-CoA: 55.1
Malonyl-CoA: 41.1
Isobutyryl-CoA: 21.5
Benzoyl-CoA: 13.9
fatty_acid: 12.4
inactive: 10.4
2-Methylbutyryl-CoA: 5.9
trans-1,2-CPDA: 0.0
Propionyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
Ethylmalonyl-CoA: -2.6

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; Methylmalonyl-CoA: 58.3%; Ethylmalonyl-CoA: 54.2%

ATCC10864_000907

PKS_AT (575..896): pk

minowa: Methoxymalonyl-CoA

Prediction, score:

Methoxymalonyl-CoA: 75.7
Methylmalonyl-CoA: 71.9
Malonyl-CoA: 58.1
Isobutyryl-CoA: 51.9
Ethylmalonyl-CoA: 35.0
Propionyl-CoA: 24.1
3-Methylbutyryl-CoA: 16.1
2-Methylbutyryl-CoA: 15.0
inactive: 13.2
fatty_acid: 11.8
trans-1,2-CPDA: 11.0
CHC-CoA: 8.7
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 66.7%; Methylmalonyl-CoA: 58.3%

MCQH01000019 - Region 2 - NRPS-like,T1PKS

Download region GenBank file

Location: 403,146 - 474,252 nt. (total: 71,107 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 403145 - 474252:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 403145 - 449768:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 431006 - 474252:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_000939

PKS_AT (540..844): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 66.2
Methoxymalonyl-CoA: 55.6
Propionyl-CoA: 51.2
2-Methylbutyryl-CoA: 26.7
CHC-CoA: 26.2
Benzoyl-CoA: 22.9
fatty_acid: 19.9
trans-1,2-CPDA: 17.2
Ethylmalonyl-CoA: 16.7
Malonyl-CoA: 10.1
Isobutyryl-CoA: 8.7
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 70.8%; Methylmalonyl-CoA: 58.3%; Propionyl-CoA: 58.3%

ATCC10864_000947

Search NORINE for peptide: strict or relaxed

AMP-binding (88..350): X

NRPSPredictor2: val, leu, ile, abu, iva

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: nhsymgh--k
Nearest Stachelhaus code:: N, A
Stachelhaus code match:: 0% (weak)

MCQH01000019 - Region 3 - T1PKS

Download region GenBank file

Location: 716,331 - 763,794 nt. (total: 47,464 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

ClusterBlast

KnownClusterBlast

SubClusterBlast

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Similar known gene clusters

No matches found.

Similar subclusters

No matches found.

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 5, location 716330 - 763794:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ATCC10864_001042

PKS_AT (546..860): pk

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 91.3
Methoxymalonyl-CoA: 89.3
Ethylmalonyl-CoA: 65.8
Malonyl-CoA: 61.5
Isobutyryl-CoA: 60.9
Propionyl-CoA: 35.4
Benzoyl-CoA: 32.1
fatty_acid: 28.2
trans-1,2-CPDA: 26.0
Acetyl-CoA: 24.3
inactive: 21.5
CHC-CoA: 20.4
3-Methylbutyryl-CoA: 17.0
2-Methylbutyryl-CoA: 15.5

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 83.3%; Methylmalonyl-CoA: 66.7%; Ethylmalonyl-CoA: 66.7%

MCQH01000019 - Region 4 - terpene

Download region GenBank file

Location: 1,151,343 - 1,172,464 nt. (total: 21,122 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

ClusterBlast

KnownClusterBlast

SubClusterBlast

Similar gene clusters

No significant ClusterBlast hits found.

Similar known gene clusters

Similar subclusters

No matches found.