LOCUS       MCQH01000069           23147 bp    DNA     linear   PLN 27-JUL-2021
DEFINITION  Aspergillus niger.
ACCESSION   MCQH01000069
VERSION     MCQH01000069
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Circumdati.
COMMENT     'Annotated using 1.8.7'.
            ##antiSMASH-Data-START##
            Version      :: 5.1.1
            Run date     :: 2021-07-27 13:34:31
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1498
            Orig. end    :: 24645
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     mRNA            complement(1..3306)
                     /locus_tag="ATCC10864_003823"
                     /product="hypothetical protein"
     gene            complement(1..3306)
                     /locus_tag="ATCC10864_003823"
     CDS             complement(1..3306)
                     /NRPS_PKS="Domain: AMP-binding (6-406). E-value: 4.7e-82.
                     Score: 267.5. Matches aSDomain:
                     nrpspksdomains_ATCC10864_003823_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (528-593). E-value: 9.6e-15. Score:
                     46.4. Matches aSDomain:
                     nrpspksdomains_ATCC10864_003823_PCP.1"
                     /NRPS_PKS="Domain: TD (634-884). E-value: 6.8e-68. Score:
                     220.2. Matches aSDomain:
                     nrpspksdomains_ATCC10864_003823_TD.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /codon_start=1
                     /db_xref="PFAM:PF00501"
                     /db_xref="PFAM:PF00550"
                     /db_xref="PFAM:PF01073"
                     /db_xref="PFAM:PF01370"
                     /db_xref="PFAM:PF07993"
                     /db_xref="PFAM:PF13193"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 288;
                     E-value: 1.9e-87)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ATCC10864_003823"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_003823-T1"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-85, bitscore:
                     279.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.7e-11, bitscore:
                     35.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.9e-60, bitscore:
                     197.4, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MERIVYSHAQQAPDVPAVVADNTTLTYRELVSEAIHLAEFLDAEG
                     IKAPEEPVGILLGSGLGLIVAQLAVRLVGATCVPIEPTLPELRIAGMFNQVHVRYIITE
                     KDGPISLSGFRTVHMPPVGQKAHAALSNWEFRPETDRSHVLFTSGSTGKPKPVQIRPEN
                     ILHLATNTPVTPLLTSDRVAEFNNPGFDLSLFEIWATLLSGATIVVVPRHIATDPGAIA
                     SYLQEHQVSVIFITAALFRIIVSACPSAFSTLRHVLMGGDVANVQAIRSVFEHGPPQHL
                     WNTYGPTECTTLTTMHEVTPADTDTDLIPIGRPVGDMEIILLDEEQRLITEPGQPGEVY
                     IAGPQQAAGYFARPAETAEQFVEITRLGRHGEDHGVVRVYRTGDRAEWGADSNVLDFLG
                     RTDSQVKHGGFRVELGEIERALERHPRVHTAVVARQPPLTTDGTHALVAFVVSDDGSVD
                     PHAVTQFARERLPSYMIPDAIEVMGELPLTSNGKFDRATLVQRRMDALQKQKPNVDAPP
                     AQSNGDAQDKHTLLRDIWMDILHLPHIHDGDDFFALGGTSMQAAELIARVQIHMKVLIS
                     MEELYRHSRFDDLVRQVQPAEPLTHGNAPDDTHVWMQDVDLVNDIAWIPDWQSPDEGRV
                     FLTGATGFVGAHLLHRLLHKPTVQQVACLARPQGSLSAAARVRQTLETYDLWPASDHLA
                     QKLLVLPGDLAGPHLGLGRKQFTWLADWASVIFHLGAKVNFCESYREHRAANVVGTRNI
                     LSLAVTGRRKPLHYVSSVDAWGPTGAILGTRELPEDAPLQPHIQGLRYDLGYAQSQWTA
                     EAMVRRLRDEPPHHLPVAIYRPGFIIGDAVTGASNPNDFFTRLIVGCIQMGTFPRLTQC
                     LEYVTVDYVVDAVTGASNPNDFFTRLIVGCIQMGTFPRLTQCLEYVTVDYVVDAVTGAS
                     NPNDFFTRLIVGCIQMGTFPRLTQCLEYVTVDYVVDAMLHIAGDNALLGRSYHLVPPDP
                     KASVTVEGTCRVLNEAGHKVRMVDYEDWAAQAVREQRGPNTALAPLMPMVQERVLGRLT
                     RWEASQYTPWYRADNTIAALKERPDLVCRPLDASMLRRFIGFWNRKGFYSVPE"
     protocluster    1..23147
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1498:4804](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(1..3306)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..23147
                     /SMILES="NC(CC(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23147
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     aSDomain        complement(655..1404)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC10864_003823_TD.1"
                     /evalue="6.80E-68"
                     /label="ATCC10864_003823_TD.1"
                     /locus_tag="ATCC10864_003823"
                     /protein_end="884"
                     /protein_start="634"
                     /score="220.2"
                     /tool="antismash"
                     /translation="VFLTGATGFVGAHLLHRLLHKPTVQQVACLARPQGSLSAAARVRQ
                     TLETYDLWPASDHLAQKLLVLPGDLAGPHLGLGRKQFTWLADWASVIFHLGAKVNFCES
                     YREHRAANVVGTRNILSLAVTGRRKPLHYVSSVDAWGPTGAILGTRELPEDAPLQPHIQ
                     GLRYDLGYAQSQWTAEAMVRRLRDEPPHHLPVAIYRPGFIIGDAVTGASNPNDFFTRLI
                     VGCIQMGTFPRLTQCLEYVTVDYVVDAVT"
     aSModule        655..3288
                     /complete
                     /domains="nrpspksdomains_ATCC10864_003823_AMP-binding.1"
                     /domains="nrpspksdomains_ATCC10864_003823_PCP.1"
                     /domains="nrpspksdomains_ATCC10864_003823_TD.1"
                     /final_module
                     /locus_tags="ATCC10864_003823"
                     /monomer_pairings="leu -> leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(1528..1722)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC10864_003823_PCP.1"
                     /evalue="9.60E-15"
                     /label="ATCC10864_003823_PCP.1"
                     /locus_tag="ATCC10864_003823"
                     /protein_end="593"
                     /protein_start="528"
                     /score="46.4"
                     /tool="antismash"
                     /translation="TLLRDIWMDILHLPHIHDGDDFFALGGTSMQAAELIARVQIHMKV
                     LISMEELYRHSRFDDLVRQVQ"
     CDS_motif       complement(2053..2118)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC10864_003823_0003"
                     /evalue="1.90E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="ATCC10864_003823"
                     /protein_end="418"
                     /protein_start="396"
                     /score="29.7"
                     /tool="antismash"
                     /translation="FLGRTDSQVKHGGFRVELGEIER"
     aSDomain        complement(2089..3288)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC10864_003823_AMP-binding.1"
                     /evalue="4.70E-82"
                     /label="ATCC10864_003823_AMP-binding.1"
                     /locus_tag="ATCC10864_003823"
                     /protein_end="406"
                     /protein_start="6"
                     /score="267.5"
                     /specificity="consensus: leu"
                     /tool="antismash"
                     /translation="SHAQQAPDVPAVVADNTTLTYRELVSEAIHLAEFLDAEGIKAPEE
                     PVGILLGSGLGLIVAQLAVRLVGATCVPIEPTLPELRIAGMFNQVHVRYIITEKDGPIS
                     LSGFRTVHMPPVGQKAHAALSNWEFRPETDRSHVLFTSGSTGKPKPVQIRPENILHLAT
                     NTPVTPLLTSDRVAEFNNPGFDLSLFEIWATLLSGATIVVVPRHIATDPGAIASYLQEH
                     QVSVIFITAALFRIIVSACPSAFSTLRHVLMGGDVANVQAIRSVFEHGPPQHLWNTYGP
                     TECTTLTTMHEVTPADTDTDLIPIGRPVGDMEIILLDEEQRLITEPGQPGEVYIAGPQQ
                     AAGYFARPAETAEQFVEITRLGRHGEDHGVVRVYRTGDRAEWGADSNVLDFLGRTDSQV
                     KH"
     CDS_motif       complement(2224..2310)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC10864_003823_0002"
                     /evalue="6.30E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="ATCC10864_003823"
                     /protein_end="361"
                     /protein_start="332"
                     /score="34.5"
                     /tool="antismash"
                     /translation="PGQPGEVYIAGPQQAAGYFARPAETAEQFV"
     CDS_motif       complement(2830..2877)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC10864_003823_0001"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ATCC10864_003823"
                     /protein_end="159"
                     /protein_start="143"
                     /score="18.2"
                     /tool="antismash"
                     /translation="VLFTSGSTGKPKPVQIR"
     mRNA            join(4499..5267,5317..5459,5507..5872)
                     /locus_tag="ATCC10864_003824"
                     /product="hypothetical protein"
     gene            4499..5872
                     /locus_tag="ATCC10864_003824"
     CDS             join(4499..5267,5317..5459,5507..5872)
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-410). E-value:
                     1.6e-41. Score: 134.3. Matches aSDomain:
                     nrpspksdomains_ATCC10864_003824_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="PFAM:PF00155"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109:8-amino-7-oxononanoate synthase (Score: 279.4;
                     E-value: 7.1e-85)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC10864_003824"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_003824-T1"
                     /transl_table=1
                     /translation="MNPGLDTLRHKLEQTLALRRKKGRLIEPPSPAKLDGLIDFSSNDS
                     LSLTTPGILTEAFLKQLEMHSAFTIGSTSSRILDGTKQYLIDLERDIAKFHRAKTAMFF
                     NSGYDANVALWSTIPQPGDFILYDEYAHASIHDGMRRGRATTLSFKHNDCQAFKLCLEK
                     IRTENSGIAEGRQVVFVALESFYSMDGDSAPVVELLEVAHKALPRKNFIFSMDEAHSNG
                     IMGPNGSGFVCHYGLEEHSPIRLQTCGKALGSTGAALLCNETIKSVLINYARGIIFSTA
                     PSFLSVAAVRAGYDIIGSKEGEDRRKRLQSNVYRFYTQLTSHPDWPQIKRKGTFYLPTE
                     HTWYLGPFQSPIVPLVPQHDLAVNLEKYLEQAKYRVITVHYPIVPDRTGRVRIVLHADH
                     TPQQIDHVVELIMQWANKQGARGAHL"
     aSDomain        join(4607..5267,5317..5459,5507..5824)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC10864_003824_Aminotran_1_2.1
                     "
                     /evalue="1.60E-41"
                     /label="ATCC10864_003824_Aminotran_1_2.1"
                     /locus_tag="ATCC10864_003824"
                     /protein_end="410"
                     /protein_start="36"
                     /score="134.3"
                     /tool="antismash"
                     /translation="LIDFSSNDSLSLTTPGILTEAFLKQLEMHSAFTIGSTSSRILDGT
                     KQYLIDLERDIAKFHRAKTAMFFNSGYDANVALWSTIPQPGDFILYDEYAHASIHDGMR
                     RGRATTLSFKHNDCQAFKLCLEKIRTENSGIAEGRQVVFVALESFYSMDGDSAPVVELL
                     EVAHKALPRKNFIFSMDEAHSNGIMGPNGSGFVCHYGLEEHSPIRLQTCGKALGSTGAA
                     LLCNETIKSVLINYARGIIFSTAPSFLSVAAVRAGYDIIGSKEGEDRRKRLQSNVYRFY
                     TQLTSHPDWPQIKRKGTFYLPTEHTWYLGPFQSPIVPLVPQHDLAVNLEKYLEQAKYRV
                     ITVHYPIVPDRTGRVRIVLHADHTPQQIDHVVELI"
     mRNA            complement(join(6217..7045,7097..7547,7597..7801,
                     7850..8743,8798..9589,9639..10071,10127..10191,
                     10248..10277,10337..10471,10531..10707))
                     /locus_tag="ATCC10864_003825"
                     /product="hypothetical protein"
     gene            complement(6217..10707)
                     /locus_tag="ATCC10864_003825"
     CDS             complement(join(6217..7045,7097..7547,7597..7801,
                     7850..8743,8798..9589,9639..10071,10127..10191,
                     10248..10277,10337..10471,10531..10707))
                     /codon_start=1
                     /db_xref="PFAM:PF00069"
                     /db_xref="PFAM:PF07714"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 190.1;
                     E-value: 9e-58)"
                     /gene_kind="regulatory"
                     /locus_tag="ATCC10864_003825"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_003825-T1"
                     /sec_met_domain="Pkinase (E-value: 6.8e-72, bitscore:
                     235.3, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MVSRSSETSEGPPPPSKIPGTPAKTRLSRLNSSPAKQDKPKDDRV
                     VKSSAKDVAELKDYQLGDCLGKGAFGSVYRALNWNTGETVAVKQIKLVDLPKSELRVIM
                     LEIDLLKNLDHPNIVKYQGFVKSAETLNIILEYCENGSLHSIAKNFGRFPENLVGLYMS
                     QVLHGLLYLHEQGVIHRDIKGANILTTKEGLVKLADFGVASRTTGLSESSVVGTPYWMA
                     PEVIELSGATTASDIWSLGCTVIELLEGKPPYYNLQPMPALFRIVNDDHPPLPQGASPA
                     VKDFLMQCFQKDPNLRVSARKLLKHPWIVNARRSDSVVPKKSTEYEEAVKSVQEWNEAL
                     RSPDTGTLRKPYRYDAQGAALRPEMAPSRYTPTKDILPSPVSKHVTDRFRSPDSTEEDN
                     WDDDFATAISPSALQLPHLRPQDNFGGMLSSEKLKAFASLDGTVLKSEDGFDDFDDPFS
                     QQPGESDPLRTIRPYSAKPTGMENMSQQTKPTIAAMHHNVPVLKTPVPPLRPQRPTSYF
                     KENSVEDYSDLISANEDILDDKLSAFQDIDEEGSDISIPSPSKEVVRYQASPDHDEDHQ
                     PQLRKRISVKRHRSAIEIQKFAENERDEDFSDILGADEVALDKPESDEGSDRSTLMLNS
                     KLSNNSWLGDQDDEDDPFAQLEEGLDEVDLEANIARDKYARLRGQVEGLVSSLKTSQDE
                     DVLGEISEQLLTVFCDLPETKNIIISAHGMLPILEILDICRRRDIILCLLRIVNAIIFN
                     DYEIQENLCFVGGIPIINEFASKKYPREIRLEAAAFVQQMYQTSTLTLQMFVSAGGLNV
                     LVEFLEDDYEDERDLVLIGVNGIWSVFDLQGSTPKNDFCRILSRNSVLDPLSLVLSRVL
                     DEEGELAEIVEGRIANIFFIFSQAENHVKEMVAERTVLHRVLKELKRMTPAHQITMLKF
                     IKNLSMLSTTLDSLQNSNAIDVLTDLLRSTIKRPHFREVSNQILNTIYNMCRLNKSRQE
                     DAALNGIVPLLQKIVKTERPLKEFALPILCDMAHSGKVGRRELWRNKGLAFYISLLSDP
                     YWQVTALDAIFTWLQEETAKVEEHLLDNRYDKMSFTDSIVRCLTISKANAFENILEPLQ
                     KLLRLSPPIASTFARPDLFTRLGQKLHHNKAAVRLNLLRIISSICDSSEEQGGLLAKYG
                     LLEAIRELEHDPAILVRDMAGKLIQSNERSESFSLEKRKPGMRRKSTSTTPPGYLANQS
                     APATPQINRFNQPKAYFDGRESQRHPRPSLSSSALALRPGSRDGTGPSLSAGLSSSAGP
                     SRNRLSRGVANRLSQVELLAEEETRPSSSLSRRRSILPQRRRPTHADSDWAS"
     mRNA            complement(11579..12829)
                     /locus_tag="ATCC10864_003826"
                     /product="hypothetical protein"
     gene            complement(11579..12829)
                     /locus_tag="ATCC10864_003826"
     CDS             complement(11579..12829)
                     /codon_start=1
                     /locus_tag="ATCC10864_003826"
                     /note="BUSCO:EOG09260KM4"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_003826-T1"
                     /transl_table=1
                     /translation="MIELGLSRIVRLLQQTPLTWKAIHIAGTNGKGSISAYLSHLLSTG
                     GVRCGRFTSPHLIDRWDCITIGEKVVQESLFRQIEARVKLRDQTLGIGASEFELLTATA
                     FEIFNHERVDIGVVEVGMGGRLDATNILTDVLVSVIAKIGLDHQFLLGDTIEEIAREKA
                     GIMKSGVPCVVDGTNSVEVLRTLEGHIKELGIDAIFTRPDTPEYHSPSLGQLFATLDLL
                     PHQRANMSCAVSALKLALPRFRPDIDVDALVPQLSKVEWPARLQKILLKPLVDREEPVL
                     LDGAHNTQSAEVLGEYVDYKLRPQGTNVTWVIAASRGKDIESLFHSIIKAGDRVAITAF
                     GPVDGMPWVKANDPEEVASCVRSIAGIGQVQTFGEDISGAIHWACEQASGAPLVIAGSL
                     YLASDVLRLLREAQKQL"
     mRNA            join(13641..13651,13766..15059)
                     /locus_tag="ATCC10864_003827"
                     /product="hypothetical protein"
     gene            13641..15059
                     /locus_tag="ATCC10864_003827"
     CDS             join(13641..13651,13766..15059)
                     /codon_start=1
                     /locus_tag="ATCC10864_003827"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_003827-T1"
                     /transl_table=1
                     /translation="MGIPLFCESSADAPKNNAVKDPCAAARSAIRRQATIRRPSRYGGS
                     ALRSATLRSPFPRPLADEIEREANGLQRHVRSPLSNSSSADDPFDLARGLLDSDRREAG
                     QRLLSDALRHGRPGQRLRIPRSSALPDLYNRPSPGDDTTNRLDQTHPQLTPRFAPAIAY
                     HRTASPQARPEAARLSPYLRPDGLGGDLSISAGFPTLRRVGERSINEANRPNRESAIDG
                     LGDRQRSLSPDDDHANDAWETLLTTITPDTNLPSADSSFTSASASGTNASTIGTSRSSA
                     TSLQSLPNPMDSSTGTVQMVLDPYPEFLNPCDYSSSSDSDSDSETGISGNALFRRYRRV
                     RQMESLRRAQHLQSTMSNHPPIPTISFAFSDSSSTSTDPDLQQMQAILDRLARREDIPE
                     EWWAAAGLSRTLGRRLGANDDTNDTDSVDGPLRSR"
     mRNA            join(15950..15989,16071..16741)
                     /locus_tag="ATCC10864_003828"
                     /product="hypothetical protein"
     gene            15950..16741
                     /locus_tag="ATCC10864_003828"
     CDS             join(15950..15989,16071..16741)
                     /codon_start=1
                     /locus_tag="ATCC10864_003828"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_003828-T1"
                     /transl_table=1
                     /translation="MDDQVSRLVDKIWNKFQSTPKDTRLLIAISGIPGSGKTELATMMA
                     NRINRRYLTQHPESPQVATNVPMDGYHLTRAQLSEMPDPAYAIARRGAAFTFDGEKFLQ
                     LVRALREQVTPETQSLYAPSFDHAVKDPVDDDILIPASCRVIFFEGNYLSLNKEPWNRA
                     AELMDELWFVEVDFEVAKKRLIKRHVKAGIASDEAEAEKRVLENDLVNGKEIVDYRLDL
                     QELVVSRYDPAWDA"
     mRNA            join(18435..18532,18592..18740,18805..19052)
                     /locus_tag="ATCC10864_003829"
                     /product="hypothetical protein"
     gene            18435..19052
                     /locus_tag="ATCC10864_003829"
     CDS             join(18435..18532,18592..18740,18805..19052)
                     /codon_start=1
                     /locus_tag="ATCC10864_003829"
                     /note="SECRETED:SignalP(1-21)"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_003829-T1"
                     /transl_table=1
                     /translation="MLFAHFAFLVTLLALGGLTVATQTRPCLVSAMRSQSDPDNLQDIC
                     ATNVGKVWAKIVEFCGDERQSALEQLKDTCTSAGYTIAYKPTASSDIASHSTALFSSTK
                     PSSVIASSTGISTSSSAPDASSSLCPSTHPNQTISLGSADRGASAAAFAAVVFVGFAAT
                     L"
     mRNA            join(19771..19789,19900..20057,20111..21051,21101..22580)
                     /gene="RNR1"
                     /locus_tag="ATCC10864_003830"
                     /product="ribonucleotide-diphosphate reductase subunit
                     rnr1"
     gene            19771..22580
                     /gene="RNR1"
                     /locus_tag="ATCC10864_003830"
     CDS             join(19771..19789,19900..20057,20111..21051,21101..22580)
                     /codon_start=1
                     /db_xref="PFAM:PF00317"
                     /db_xref="PFAM:PF02867"
                     /db_xref="PFAM:PF03477"
                     /gene="RNR1"
                     /locus_tag="ATCC10864_003830"
                     /product="ribonucleotide-diphosphate reductase subunit
                     rnr1"
                     /protein_id="ncbi_ATCC10864_003830-T1"
                     /transl_table=1
                     /translation="MFVYKRDGRKERVQFDKITARVSRLCYGLDPEHVDAAAITQKVIS
                     GVYQGVTTVELDNLAAETAAYMTVTHPDYAILAARIAVSNLHKQTKKQFSLVISDLYHY
                     VNPKNNQPAPMISKETYEIIMKHADELNSAIVYDRDFNYNFFGFKTLERSYLLRINGKV
                     AERPQHLLMRVAVGIHGSDIEKAIETYHLMSQKYFTHASPTLFNAGTPQPQLASCFLVD
                     MKEDSIDGIYDTLKTCAMISKTAGGIGLNVHRIRSTGSYIGGTNGTSNGLVPMLRVFNN
                     TARYVDQGGNKRPGAFAIYLEPWHSDVFEFLDLRKNHGKEEVRARDLFYALWTPDLFMK
                     RVEANGDWTLFCPNEAPGLADVYGDEFDALYEKYEKEGRGRRTIKAQKLWYAILEAQTE
                     TGNPFMLYKDACNKKSNQKNLGTIRSSNLCTEIIEYSAPDEVAVCNLASLALPTFVDAA
                     RGEYDFGKLHEVVQVLVRNLNKIIDINYYPVPEAKKSNFRHRPIALGVNGLADAFLALR
                     LPFDSAEARQLNIQIFETIYHAGLTASSDLAKEFGTYETYEGSPVSQGILQYDMWDRTP
                     TDLWDWAALKAKIAQTGVRNSLLVAPMPTASTSQILGFNECFEPYTSNIYSRRVLAGEF
                     QVVNPWLLKDLVDLGLWSDNMKNRIIAEGGSVQNIPNIPSDIKALYKTVWEISQRTILQ
                     MAADRGAFIDQSQSLNIHLKEPTMGKITSMHFAGWKMGLKTGMYYLRTMAASAPIQFTV
                     DQEQLKVEDTNVARTNAAYKKRAVGAASSTYSAVPRGQAPVNGHSENGVNGINGSNNGS
                     PRALAADASSTQENGPQEEDSQQESEERENDIYSQQVLQCSIENKEACIMCQG"
     mRNA            complement(join(22829..22941,23069..23147))
                     /locus_tag="ATCC10864_003831"
                     /product="hypothetical protein"
     gene            complement(22829..23147)
                     /locus_tag="ATCC10864_003831"
     CDS             complement(join(22829..22941,23069..23147))
                     /codon_start=1
                     /locus_tag="ATCC10864_003831"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_003831-T1"
                     /transl_table=1
                     /translation="MDSIKQNLENAKNKGKDYYNQMTGQQNSDASQYAEQAKTKANEGM
                     DKTKQTAKDYMPNQAGDH"
ORIGIN
        1 ctactccggc acactgtaga accccttccg attccagaac ccaataaacc gccgtagcat
       61 gctcgcgtcc agcgggcgac acaccaggtc gggccgctcc ttcagcgccg cgatggtatt
      121 gtccgcgcgg taccagggcg tgtactggct ggcctcccag cgggtgaggc ggccgagcac
      181 gcgttcctgc accatgggca tcagcggggc gagggcggta tttgggccgc gctgctcgcg
      241 cactgcctgc gccgcccagt cctcatagtc gaccatacgc actttatgcc cagcctcatt
      301 gagcacgcga caagtcccct cgaccgtcac ggaggccttc gggtccggcg ggacaagatg
      361 atacgagcgg ccgaggaggg cattgtcacc ggcgatatgc agcatggcgt cgacgacgta
      421 gtcgacagtg acgtactcga ggcactgagt gaggcgtggg aaggtcccca tctggatgca
      481 gccgacgata aggcgggtga agaagtcgtt cgggttgctg gcgccggtga cggcgtcgac
      541 gacgtagtcg acagtgacgt actcgaggca ctgagtgagg cgtgggaagg tccccatctg
      601 gatgcagccg acgataaggc gggtgaagaa gtcgttcggg ttgctggcgc cggtgacggc
      661 gtcgacgacg tagtcgacag tgacgtactc gaggcactga gtgaggcgtg ggaaggtccc
      721 catctggatg cagccgacga taaggcgggt gaagaagtcg ttcgggttgc tggcgccggt
      781 gacggcgtcg ccgatgatga agcccgggcg atagatggcg acggggaggt ggtgcggggg
      841 ttcgtcgcgg agccggcgca ccatcgcctc ggcggtccac tgcgactgcg cgtagccaag
      901 atcatagcgg aggccctgga tgtgcggctg gaggggtgcg tcttcgggga gctcgcgcgt
      961 gcccaggatg gcgccggtgg gcccccaggc gtcgacgctg gagacgtagt ggagtggctt
     1021 gcggcggccg gtgacagcga ggctgagaat gttgcgcgtg ccgacaacat tggcggcgcg
     1081 gtgctcgcgg tacgactcgc agaagttgac cttcgcaccg aggtggaaga tcacggacgc
     1141 ccagtcagcg agccaggtga actgcttgcg gccaaggccg aggtgagggc cggccaggtc
     1201 gccggggagg acgaggagct tctgggcgag gtggtctgag gctggccaga ggtcgtaagt
     1261 ctcgagggtt tggcgcacgc gcgcggcggc ggagagggag ccttgaggcc gggcaagaca
     1321 ggcgacctgc tggacggtgg gtttgtgcaa gagccggtgg aggagatgcg cgccgacgaa
     1381 gccggtggcg ccagtgagga agacgcggcc ctcatcgggg ctttgccagt cggggatcca
     1441 ggcgatatcg ttgacgaggt cgacgtcttg catccagacg tgggtgtcgt cgggggcgtt
     1501 cccgtgggtg agaggttcgg ccggttggac ctggcgaaca aggtcgtcga atcgcgagtg
     1561 ccggtataat tcttccatgg agatgagaac tttcatgtgg atctgaacgc gggcgatgag
     1621 ctcggccgcc tgcatggatg tgccgccgag ggcaaagaag tcatcgccat catggatatg
     1681 gggtagatgg aggatgtcca tccagatatc gcggagaaga gtgtgcttat cctgtgcgtc
     1741 gccgttggac tgggccgggg gagcgtccac gttgggtttc tgtttctgta gagcatccat
     1801 ccggcgctgc acaagtgtgg cacgatcaaa tttgccgttt gaggtgagag gaagctcccc
     1861 catgacctcg atggcatcgg ggatcatgta cgacgggaga cgctctcgcg cgaactgggt
     1921 cacagcatgc ggatccacgc ttccatcgtc actcacgaca aatgcaacta gtgcatgcgt
     1981 accgtcggtc gtcaacggcg gctgtcgagc gaccaccgct gtgtgcactc ttgggtgcct
     2041 ctctagggca cgctcaatct cgcccagttc tacccggaag cctccatgtt tgacctggga
     2101 gtcagtgcgt ccgagaaagt ccaagacatt ggagtcggct ccccactcag ccctatctcc
     2161 cgtgcgatag actcgcacga cgccgtggtc ctcaccgtga cgacccagcc gagtaatctc
     2221 aacaaactgc tccgcggtct cggcaggccg ggcgaagtag ccggcagcct gctggggccc
     2281 agcgatgtag acctcgcccg gctggcccgg ctctgtgatg agccgttgct cttcatcaag
     2341 caggataatc tccatgtctc cgacagggcg gccaatgggg atcaaatccg tgtctgtgtc
     2401 tgcaggagtg acctcatgca tcgtcgtgag agtggtacac tctgtcggac cgtatgtgtt
     2461 ccataaatgc tggggaggac catgttcgaa cacgctgcgg atcgcttgca cgttggcgac
     2521 gtcgccaccc atgaggacat gacgcagggt gctaaacgcc gaggggcagg ccgagacgat
     2581 gatgcggaag agcgccgccg tgatgaagat cacagatacc tgatgttcct gcaagtacga
     2641 ggcgatggct cctgggtcgg ttgcaatgtg tcgtgggacg acaacaatcg tagccccaga
     2701 gagaagagta gcccatatct caaacagact cagatcgaag ccgggattgt tgaactcggc
     2761 cacgcgatca ctagtgagta gaggagtgac cggcgtgttc gtggccagat ggaggatatt
     2821 ctcagggcga atctgcacag gcttgggctt gccggttgac ccagacgtaa agaggacatg
     2881 gctgcgatct gtctctgggc gaaactccca gtttgatagt gccgcgtgcg ccttctgtcc
     2941 cacggggggc atgtgtacgg tgcgaaagcc ggagagactg ataggcccgt ccttttccgt
     3001 aattatgtag cgcacatgga cttgattgaa catgcccgcg atgcgaagct ccggaagagt
     3061 aggctcaatg ggcacacaag tggccccaac cagacggact gcaagttgcg cgacaatcag
     3121 tccaagccct gaaccgagaa ggatccctac gggctcttcc ggggctttga tgccctccgc
     3181 gtcgagaaat tccgcaagat ggatcgcctc agacaccagc tcacgatatg tgagcgtggt
     3241 attgtctgcc acaacagcgg gaacgtccgg ggcttgttga gcgtgagaat acacaatgcg
     3301 ttccatgatg gttgtaggga gtcgattaaa tgcgagaata gtaagatgat ggaggacgat
     3361 gaattaagag atgtgagagg ccaatatata tgattgaaga agtgcctttg gactgtggtg
     3421 ccgtagtaca tcttccagga ttaatatcca agattaggtt ttattctgca ggaaataacg
     3481 ctagaggttt cttacatgtc tactaaatat tgattatttc tataatctac aatactggcc
     3541 cagctgaagt taaaagaaac agttatagaa actgattagt tataagactt gtatagaaaa
     3601 aaaataaact atccttcttg cacagatcaa gtctatacac gcagcgacgt tatagaagag
     3661 ctgttcgagt actggatcca tggaatacgg ctgaatgaag aactgcaaga gaagtcaaaa
     3721 gtcaatgaca agaaatgcca ccattttcgg gtctgttcag ttcatcatga catcaacttt
     3781 cggccctgat gtcactcgca ccttcccttc tcagcttcct ctctcgtgct cgttccttct
     3841 caaacaaggc aactgcatag gtattctgac tattccggaa gtaacatcag agtttcctac
     3901 atggctgacg atgattcttt ttgtgatcta tatcgctgac tcggttacaa ttatactgat
     3961 tagctatagg ctatagacta accatttcag tggctggcgt agaaaagttg atgcccagca
     4021 ccttgtctgc ttcattaggc gtagcacgcc gccgggcagt acttacaagc tgcagtagat
     4081 atgttccgaa gagtcatcag aaacaatagg agaaatgttc tatgtagccg aatgacaatc
     4141 tcttcataat ctagagatac tgacttgatc aggaatcaac agtcagctat agaatatcct
     4201 ccattttact tctgtaacct ttgcgatgca gtgagcatag tacattggac agcccctatt
     4261 ctgtcagaag ccgcaaacat gagggtattg cgtcacgcat aaatccttga acctgtagcg
     4321 cgggggttca actgccacat accggaatgt atataagtgg gcgttgtccg ggactaggag
     4381 agcaagatga tactggaagc ataggcgtca gatgcagaac atctcagccg acgaagacag
     4441 aaaagagaac cagcctattt gcatcataca attcctcacc atcgttgtaa gaatcaaaat
     4501 gaatcctgga ctcgatactc ttcgtcacaa gctcgaacag acattggctc tccggcgcaa
     4561 gaaagggcgt ctgatcgagc cgccttcgcc ggcaaagctg gacggcttga ttgatttcag
     4621 ctctaatgac tcgctgtctc tcactactcc cgggattctg accgaggctt tcctgaaaca
     4681 gctcgagatg cattctgcgt tcaccatcgg aagtacctcg tcgcggattt tggacggtac
     4741 caagcagtac ctgattgacc tcgaacggga catagccaag ttccaccgtg ccaaaacagc
     4801 catgtttttc aattcgggct atgatgccaa cgtggcgctc tggtccacga ttcctcagcc
     4861 cggtgacttc attctgtatg atgagtatgc gcatgcgagc atccacgatg ggatgcgccg
     4921 tggtcgggcg accactctgt ctttcaaaca caacgattgc caggccttca aattgtgttt
     4981 ggagaagatt cgaaccgaga actcgggaat agcagaggga cgtcaggtgg tattcgtcgc
     5041 tctcgaatcc ttctacagca tggatgggga ctccgctccc gttgtcgagc tgctcgaggt
     5101 ggcgcacaag gcactccccc ggaagaactt tatattttcg atggacgagg cgcattccaa
     5161 tgggatcatg ggaccgaatg gctctgggtt tgtgtgtcac tacggattgg aggagcattc
     5221 ccccatccgg cttcaaacat gtggcaaggc gctggggtcc acgggtggtg agtgcctagc
     5281 atctcctgta atcagttatc tttctgacag ggatagctgc tcttttgtgc aacgagacca
     5341 tcaaatctgt tctcatcaac tatgcccgag ggattatctt cagtacggca ccgagtttcc
     5401 tcagtgtggc tgcggtgcga gcaggatacg acatcatagg cagtaaagaa ggcgaagatg
     5461 tgggtataag ttccctcggg gatcaccatc tactaacagt aagcagcgtc gaaaacgcct
     5521 tcaaagcaat gtgtaccgct tctacacaca attgacatcg catccagatt ggccgcagat
     5581 caaacgcaag ggcactttct acctcccaac cgaacatact tggtatttgg ggccattcca
     5641 gtctccaatc gtacctctgg ttcctcagca tgacctcgca gttaacctgg aaaagtactt
     5701 ggagcaggcc aaatacaggg tgattaccgt gcattaccct attgttccag acaggacggg
     5761 tcgcgttcga attgttttgc atgcagatca tactccgcag cagattgatc atgttgtgga
     5821 acttatcatg cagtgggcaa ataagcaggg ggcaagaggg gctcatttgt gaaatcgtca
     5881 aaagtataga acatcaaata cagatgtacc ctagtctaca caaagttcga tatggaagaa
     5941 ataagattgc acttgtatgt tatccacaat tatctacatg ggccatttcc ctccctgaca
     6001 gttccgtctt cctgtacccc gaataccagc ctgagagaga tcccatcccc gccggaaagc
     6061 acatcgacaa aagaatgtgt atacacagtc aaagcaaatc acaagtaaac ctagtactcc
     6121 aatcctatgc aatgcaaata caatgtaccc atctacttcc cagtctcctg tctacaaatg
     6181 agccaattgg cgcaccccgg gtcggcatga ggtccgctag gacgcccagt ccgaatcagc
     6241 atgcgttggt cgtcggcgct gaggaaggat ggaacgtcga cgggagagtg agctcgacgg
     6301 tcgagtctcc tcttcggcca ggagctctac ttgtgatagc ctgttagcca ctcctcgaga
     6361 cagcctgttc ctcgatgggc cagcactgct gctgagtccg gctgacagag agggaccagt
     6421 gccatccctg ctgcctggtc gtaatgccag agcagagctg ctaagggagg gccgcgggtg
     6481 tcgctggctt tcccgtccat caaaataagc cttgggttga ttgaaccgat tgatctgtgg
     6541 ggtggctggt gcggactgat tcgcaaggta gcctgggggc gtggtagacg tgctctttcg
     6601 tctcatacca ggcttgcgtt tctcgaggct gaacgattca cttctctcat tggattggat
     6661 cagcttgcca gccatgtctc taaccagaat ggccgggtca tgctccaact cccggattgc
     6721 ttccaaaagt ccatatttcg caagaaggcc accttgttct tcgctagaat cgcagatgct
     6781 cgagataata cgcaggaggt ttagccggac agcggccttg ttatggtgta atttctgtcc
     6841 tagccttgtg aaaagatcag ggcgcgcaaa tgtcgaggca ataggcggac tcagtctcag
     6901 aagcttttgc aatggctcga gaatgttctc aaaggcgttc gccttcgaaa tcgtcaggca
     6961 cctgacaatg gaatccgtaa atgacatctt gtcgtagcgg ttatccaaga ggtgttcctc
     7021 aaccttggcc gtttcttcct ggagcctgcc aaagagttag accggtattc tcaatacata
     7081 cggagccgaa acataccaag taaatatagc gtccaatgcg gttacctgcc agtacggatc
     7141 cgacaacaag gagatgtaga aagccagacc cttgttgcgc cacagttcgc ggcgtccgac
     7201 ctttcctgaa tgcgccatgt cgcagagaat cggcaacgcg aactctttga gcggccgctc
     7261 ggtctttacg atcttctgaa gaagcggtac tatgccgttc agagcagcat cctcttggcg
     7321 ggacttgttc agacgacaca tattgtagat agtgttgaga atctggttgg aaacttcccg
     7381 gaagtgtggc cgtttgatgg tcgacctcaa caagtccgta agcacgtcga tggcgttgga
     7441 gttctggagc gagtcgagag ttgttgaaag catggacaaa ttcttgatga acttcaacat
     7501 agtgatctgg tgtgcgggcg tcatccgctt tagctctttc aggacccctg agaccggtta
     7561 gcaaagtgtt tgaaattgct ggactcgatg ccttactgtg cagaactgtc cgctcagcaa
     7621 ccatttcctt aacgtgattc tcggcctgcg agaaaatgaa gaagatgttg gctatccggc
     7681 cttccacaat ctcggccaat tctccttcct cgtccaagac acggctcaaa acaagtgaca
     7741 agggatccag aacagaattg cgtgataaaa tcctgcagaa atcatttttt ggagtcgaac
     7801 cctgaattaa gtcagtctct gaaaaagaaa atactgaagg cggacatact tgtaaatcaa
     7861 aaacgctcca gataccgttc accccaatga gaacgagatc gcgttcatct tcgtagtcgt
     7921 cttccaagaa ctcaaccaat acattgagac ctccagcact gacgaacatc tggagggtaa
     7981 gagtagatgt ttgatacatc tgctgcacaa aggctgccgc ttctagtcga atctctctcg
     8041 ggtatttttt ggaggcaaac tcatttatga ttgggatacc tccgacgaaa cagaggtttt
     8101 cctggatttc atagtcattg aagatgatgg cgttgacaat ccgcaacaag caaagaatga
     8161 tgtcgcgccg acggcaaatg tcaagaatct ctaatatcgg gagcatcccg tgagcactaa
     8221 tgatgatgtt cttcgtctct ggaaggtcac agaatacggt aagcagttgc tccgagattt
     8281 ctccaagcac gtcttcatct tgagatgtct ttaaagagct gacaagaccc tcgacttgac
     8341 cccgtagacg tgcgtatttg tcacgtgcga tgttagcttc cagatccacc tcatcgagcc
     8401 cttcttcaag ctgggcgaac ggatcgtcct catcatcttg atccccaagc catgagttgt
     8461 tcgatagctt tgagtttaac atcagcgtac tccgatctga gccctcatcg ctttcgggct
     8521 tatccagggc aacctcatca gcccctagaa tgtcagagaa gtcttcatcg cgttcatttt
     8581 ctgcgaactt ttgtatttct attgccgatc ggtgacgctt gacagatatc cgttttctaa
     8641 gctgtggctg atgatcttca tcatggtccg gtgacgcctg ataccggact acctccttcg
     8701 agggcgaggg gatcgatata tcactgccct cttcgtcgat atcctgagat gcgtaagaag
     8761 acgcatacta atgaatcagc ttaggggaca tgcttacctg gaaagcactg agcttatcat
     8821 ccaaaatatc ttcatttgca gagatgaggt cagagtagtc ttcgaccgag ttctctttga
     8881 agtacgatgt cgggcgctgc ggtcttaatg gtggcacagg ggtcttgaga acaggcacat
     8941 tgtggtgcat cgcagctatt gtgggttttg tctgctgaga catgttctcc atcccggtcg
     9001 gtttggccga gtaagggcga atggtccgaa gaggatccga ttcaccaggt tgctgagaga
     9061 aaggatcatc gaagtcatca aagccgtctt cggacttcaa cactgtacca tctagggatg
     9121 caaacgcctt cagcttttcg gaggaaagca ttccgccaaa attatcctgc ggtcgaaggt
     9181 gaggaagctg cagcgcactg ggagagatgg cagtagcaaa gtcatcgtcc cagttatctt
     9241 cttccgtgga gtctggcgag cggaatcgat ctgtcacatg cttggacacc gggctgggaa
     9301 ggatatcttt tgttggtgta taccgagatg gtgccatttc ggggcgcaga gcagcaccct
     9361 gagcatcgta tcggtacggt ttccgcaggg ttccagtgtc cggagaacgg agagcttcat
     9421 tccactcctg aacgctcttg actgcttcct catactcggt ggatttcttg gggaccacgg
     9481 aatcagaccg gcgagcgttg acaatccatg ggtgtttaag gagcttcctg gcggagacac
     9541 gaaggttggg atccttttgg aagcattgca tcaagaagtc tttgacagcc tggatactaa
     9601 tcagataccg agaaccaaga acggagctgg agactaaccg gagaagcacc ctgaggaagg
     9661 ggagggtggt catcattgac gatgcggaat agagccggca taggttggag attatagtaa
     9721 ggaggcttac cctccagaag ctcgatcaca gtacaaccaa gactccaaat atcggacgct
     9781 gttgtcgcac cagaaagttc aatcacctcc ggagccatcc aatacggcgt cccaacaacg
     9841 ctggactcac ttagcccagt ggttctgctg gccacaccaa aatctgcaag cttgacaagg
     9901 ccttctttcg tggtgaggat attggcccct ttgatatctc gatgaatgac accttgctcg
     9961 tgcagatata aaagaccatg gagcacctgc gacatgtaga gaccaaccag gttttccggg
    10021 aaacgcccaa agttctttgc gatcgagtgt aaagagccat tttcacagta tctgtctcgt
    10081 cagctacact gatcatggct ttagcaatca atgcgaaggt acctactcaa gaatgatgtt
    10141 tagagtttct gcagacttca cgaacccctg gtacttcaca atgttgggat gctacaacca
    10201 caggtcagct cgggtgacaa gggacatgat cggatgtcgc atcttacgtc taggttcttc
    10261 aaaagatcga tttccaactg caacactcgg cgttagcgga cagcgcctcg accagcggcg
    10321 accggagagg gattaccatg atcactcgta gttcactttt cggcagatcc accaatttga
    10381 tctgcttcac agcgacggtt tccccggtat tccaattcag ggccctgtag actgacccaa
    10441 atgcgccttt acccaggcag tcgcccaatt gctacattaa ggcaccatta gccacgcccg
    10501 tcacgggaac cagggaagcc gtattcatac ataatccttg agctccgcga catctttagc
    10561 agaagatttg acaaccctat cgtccttcgg tttgtcttgt ttggccgggc tggagttgag
    10621 tctcgacagt cgcgttttgg ctggagttcc ggggatcttg gaaggtggcg gcggcccctc
    10681 actggtttcg ctggaccggg aaaccatggt cgcgcagcgg gtggatcgag atcccctttt
    10741 cgctgttatc aaatggcact cagctgaaag cactcggatt ccgacaactg taggcttaga
    10801 cgacgaggga aggtgtggta agggcaggcg ccagagaacc gatcggatcg ctcatgtcag
    10861 cccgagctag ttattcagaa agaagagacc ttgttagtag gtttcagaca cattatgaga
    10921 tgcagcaggg agatgaatcc gcgctgaata ccgcagagaa tatggcatga tcgcatggtg
    10981 gataaaggca aaagaaaaac atacaggaac gatccttgtc ctccagtcaa gagagagccg
    11041 cgtccggttg aaacgcgtct ctacacatcg aatgcccctc cagaaaagcg aatccaatct
    11101 tccgctcgtc agaaagactc acggaaatcc aaccagaaga ttgcgaaagg accgacgaaa
    11161 agtcacggac tgctgtgcct gccggagcaa atgcaggaca ggcgggtgtt ttgaactttc
    11221 cttttctctt ttccccacag accaccacca gctggcttag gccatgacgc agcgcccggc
    11281 cgctgctgga tctccgatca gccttatcac ggtatcagac ccgcggtgcg agctgtacaa
    11341 taaccctcta caactcgtag cttgatgtac atgatatcta cctgcaatgt aatgctgcac
    11401 tttacatgtg caggtcataa gtcttgtttt gcctttgctg atttacgata ttagatcctc
    11461 ggaacaggaa atgcacttcc gttaaactaa tgtatgctta tatacagata cgccataacg
    11521 ctgcggatgt aaaaagggta tctctgtcag tagaggtcat tggacttggt gccatggctt
    11581 ataattgctt ttgtgcttcc cggagaagac gtagaacatc cgacgccagg tagaggctgc
    11641 cagcgatgac caatggcgcg ccgctagctt gttcacaagc ccaatggata gcgccggaaa
    11701 tgtcttcccc aaaggtttgc acttgtccaa tacccgcgat tgatcggaca catgaagcca
    11761 cctcttctgg atcattggcc ttgacccagg gcatgccatc aacgggaccg aacgcggtga
    11821 tggcaactcg gtcgcccgcc ttgatgatag aatgaaacaa ggattctata tccttaccgc
    11881 gcgatgccgc gatgacccag gtaacgttcg taccttgcgg acgaagtttg taatccacat
    11941 actctccgag aacctccgcc gactgagtat tgtgtgcacc atccagcaga acaggctcct
    12001 cgcgatctac caagggtttc aaaagaatct tctgtaggcg tgccggccac tcgactttcg
    12061 acagttgtgg aaccagcgca tcgacgtcga tgtcgggacg gaatcggggt aaagcaagtt
    12121 tcagagccga gactgcacag gacatgttcg ctcgctggtg aggtaggaga tccagtgtag
    12181 caaaaagctg accaagcgat ggggagtggt attcaggtgt atcagggcgt gtgaagatcg
    12241 cgtcgatgcc gagttccttg atgtgacctt cgagggttcg gagcacttca accgaattgg
    12301 tgccatcgac aacacatgga acacctgact tcataatccc agccttttcc cttgcaattt
    12361 cttcaatggt atcgccgagg aggaactgat ggtccaggcc tatcttcgcg atgaccgaga
    12421 ccaggacgtc ggtcaagatg ttcgttgcgt ccagccgacc gcccatgcca acctcaacca
    12481 ccccgatatc aacgcgctca tgattgaata tttcgaatgc agttgcggtc agtagctcaa
    12541 actcgctcgc accgattccc agcgtttgat ctcgaagctt tactctagct tcgatctgcc
    12601 ggaagagcga ctcttggacg actttctcgc cgatggtgat gcagtcccaa cgatcaatca
    12661 gatgcgggga ggtgaaacgg ccacagcgaa caccacctgt cgacaacagg tgggacagat
    12721 aagcgctgat ggaccctttg ccattggtgc cagcgatatg gattgccttc caagtcagcg
    12781 gagtctgctg gagaaggcgg acaatgcgac taagaccgag ctcaatcatc cctccaagta
    12841 tgtgatgatt gatagttgaa gagggccaat cctcatgatc agaggaagat gagggacaag
    12901 gttgtcatgg agggaaaaag gtgttatcta ttagacctcc agaaaacttg cgccgatctg
    12961 ggaaaagagt tgcccgcggg attcgggcaa gataattatc ggagagctgt caggtgccga
    13021 ccgataagaa attaatgcct aaggcagaca gggtagagag agccgaggcc ggaaccggtc
    13081 gttaccgtac gtaatacccc cagtcggagg gacaatcgag gtaactggta tcgatctcca
    13141 tggcagcaac gctgagggta gtatacacgg agttgatcca tggaaatggg caatcgtgtg
    13201 caatgtgatc aatgccattg tcagtgaaac atttagtggc cgattcaatt tcaattgaca
    13261 acccattcat ccactcttcc ctcacttcac cctttaggcg ctgtaccaga attgtacgcg
    13321 gacgatcatt ggggcgccac cactggctct gccagccacc cagaatcccc caatgtttcc
    13381 ctcaggccaa cccgcggcgc tacgaccgca agcctcaggc gcgaaatctc ttcgcctccg
    13441 ctttttaccc ttacgaggaa aaccaaatct cgccgtttct ccatcaacac atcgccctgg
    13501 ccgctgtccc cgcaatctgg ccctctccat ttaaggtctc gcgtcacttc acgctacttc
    13561 tggatgcggc ttctctcctt gatttccatt cctgcctgga ccgtcgctct ctatcctctc
    13621 tcttcccatt ctctgtagcc atgggtattc cgtgagtcca caatttctta ccctacacaa
    13681 ctttcgccgc tgtcgggatt ctacacgcga ctccatcggc caagagcgca cggaacggct
    13741 gtcatatctg actgacatga cgcagactgt tttgcgagtc ctccgcagat gctccgaaga
    13801 acaatgctgt caaagaccca tgtgccgctg cgcgctccgc aattcgtcgc caggctacta
    13861 ttcgtcgtcc ctcgcgctat ggcggctccg cgttgcgcag cgcaactctc cggtcgcctt
    13921 tccctcgtcc gctagcagat gagattgagc gtgaggcgaa tggtcttcag cgtcatgtgc
    13981 gatctccgct ttcgaattct agcagcgccg acgacccgtt cgacctggcc cgcggcctcc
    14041 tggattccga tagacgcgaa gccggccagc gactgctgag cgatgcgctc cgtcatgggc
    14101 ggcctggtca gcgattgagg ataccgcgca gctcggccct gcccgatcta tacaaccgtc
    14161 catcgccggg tgatgacacg acaaacaggc ttgaccagac tcatccccag ttaacaccgc
    14221 gttttgctcc tgcgattgca taccatagga ctgcgtctcc acaagcgcgc ccagaagctg
    14281 ctcggctatc tccatacctt cgaccagatg gccttggagg tgatctttcg atctcagcgg
    14341 gcttccctac actgcgacgt gtcggtgaac gatcgatcaa tgaggcgaat cgtcccaacc
    14401 gcgagtcggc tattgatgga cttggcgacc gacagagaag cctgagtcca gatgacgacc
    14461 atgctaacga tgcatgggag actctcctta ctacgatcac gccggatacc aatcttccga
    14521 gtgccgattc gtccttcact tccgcatctg catctggaac gaatgcgtcg acaatcggga
    14581 cttccagaag ttcggcaacc tcgctgcaga gtctgccgaa ccctatggac tcgagcacgg
    14641 gcactgtaca gatggtccta gatccatacc ctgagtttct aaacccctgt gactattcaa
    14701 gctccagtga ttccgacagc gactccgaaa ccgggatctc tggaaacgca ttgttccgtc
    14761 gctaccgtcg tgttcgccag atggagtcgc tgagacgggc tcagcatctc cagtcaacca
    14821 tgagcaacca ccctcctatc cctaccatct cctttgcatt ttccgattct tcttctacct
    14881 ctaccgatcc agacctgcag cagatgcaag ccatcttaga tcgacttgcg cgtcgcgagg
    14941 atatcccaga agaatggtgg gcggcagctg gactgtcccg cacccttggc cgccggctcg
    15001 gcgcgaacga tgacactaac gacactgata gcgtggatgg accgctcagg tcgaggtgat
    15061 catatacctt tctgtcactg tgttagatat cgagtgttta gttattaggt catctgggga
    15121 tgcttgtggt ttcgagttgt tcttagcggg ggtttcttgt ttggcgttat ggtgtcgcag
    15181 ccagggtcag tcggctgaat aagttatgga caggaatttc ccattatgag gtggaattga
    15241 tctgaagtgc atattcgggc acctattgta ctcatatatc ctggcttgtc taatgtcatt
    15301 tggtgtgaat caaacctgtg tgtcggaatt gtaagagtcg taaccgctta gcctgggatg
    15361 ggatacttca agttgctgct agccgtgggc atgtgacctc atgcattgac cagttgctcc
    15421 ttcaatggca gtgagaacgg catttgacta tcccacataa gcattaccgt ctatgttcca
    15481 ccatcttgaa ccccaagaaa tacaaaagca ccataaacat gccaagttta cttcatccac
    15541 agtctacaaa gtataaccgg cggtgcctga taagttagcc ggtcccctgt gacgtatctc
    15601 actatcgctg gcccggccgg agtcaatgcg atcgcgagac cccactctga cgacaagccc
    15661 cgccgactta tttatcccat cgagccgccg tcggagcttc tcgctgccat ccagaactgc
    15721 cattctcctg tttgtggccc atcactcggt acaggtaccg acagagcgtg tctcgaatcg
    15781 gactttctca tagcaaatct cttaacccta tccaacatct tccgcccttc aaagcgtccc
    15841 aacctttgca tgcacgggac cacgatctct gtccttgaat ccatataaaa cctactcccc
    15901 aatctacttt ctccatatat atccccttat aataatacac acaccaatca tggacgacca
    15961 agtgagtcga ctggtcgata aaatctggag taagtcttct tttccccggg gggcggggag
    16021 caacatgctc cgcaatcaac cccagcaaga aactaaccaa atctccccag acaaattcca
    16081 atccacaccc aaagacaccc gcctattaat tgccatcagc gggatacccg ggtcaggcaa
    16141 aacagagctc gcaactatga tggccaaccg catcaaccgg cgctacctta cacaacaccc
    16201 tgagtcacca caagtcgcaa ccaacgtgcc catggacggc taccatctaa cccgggctca
    16261 actatctgag atgccagacc cggcgtatgc catcgcgcgt cgcggcgcag cgttcacctt
    16321 cgacggggaa aagtttctgc agctggtccg ggcgttgcgg gaacaggtga cgcctgagac
    16381 gcagagtctg tatgcaccga gctttgatca tgcggtgaaa gacccggttg acgacgatat
    16441 actaatcccg gcgtcgtgtc gggtgatatt ctttgaggga aattacttga gcttgaataa
    16501 ggagccgtgg aatcgggcgg ctgagttgat ggatgagttg tggtttgtgg aggtggattt
    16561 tgaggtcgcg aagaagaggt taattaaaag gcatgttaag gccgggattg cgagtgatga
    16621 ggcggaggcg gagaagaggg tcttggagaa tgacctggta aatgggaagg agattgttga
    16681 ttataggtta gatctgcaag agttggtcgt tagtcggtat gatcctgcgt gggatgcatg
    16741 agtgggaaat gtgggtggat ggacacttta gagttataga cgttggtcaa gactcggtgc
    16801 ttactagact tatacttatg attacccaga tacctggata cacgacatgc atggagagat
    16861 catattagca attgaagact tgcattcaat gaactttagc ggatggacag ctctctttgg
    16921 tgttgtagat cttgctaaaa ttaggtccag atcgaaatct ttatgaagtt gactctcaaa
    16981 acgaatgact atctgcttcg tacgcctctg gactctgaca gagactagct caagctgcgt
    17041 ccacacgcca catattgaat ttgctgaaca gacgaggcac acgcagacag tccggtagta
    17101 tccagaacag caagcaacga aatttctaaa gcaaacatcc ccaattccac acaccttaga
    17161 taccgaaatt agcattctga gtacttcttc actactatac atgcatcata cctctacgat
    17221 ggacatatct acccacccat acaaaggcat cctcaggacg cttcacgctg tgctaaagct
    17281 gaggacttat tcaatatact accagggtaa actctgatct ttgaaccagt gctttgtatg
    17341 cttgtgtgtg gctagaaaag gagaatacaa taacatggtc aaattaacgt cgtacgaatg
    17401 cagatttcca actatgtcta tggtagctac tagctaaaag ctcaggtagt acagacaaca
    17461 tcacttttcc tgaagcttag catatcctgc ttaattgccg tgatctaatg gtcgaaacca
    17521 aggctgcaaa gcagtgtaca gtttgtattg catctgccgc aagggcagac gcaacggacc
    17581 ctctccctac ctaagcatct actgaaagta ggttgctgga gactcgctaa ttgtgattat
    17641 tacaagctcc tgagcgctta gggtaagata ttcatcacag agggtagtgc aaactgttct
    17701 tatatgataa cccttgagga ttgtgctgaa tctccctccg agctctgcag cttgttagga
    17761 agtcggttga ctccttacct aggactcatt atggaggtga ggatattgtt atcctgggtt
    17821 tgcatgtttc cctaagcgat agaagccatt gctgacttgg tattccggat gttccgacta
    17881 ttgctttagg gggtgtggta ggcagtaggc ggctgtagat gatagttccg atgatgcatc
    17941 aacttggaaa tggggttatt gagaggcatc caaaagagca tgtatatcag gtacactcct
    18001 agtacctatc catgactaca ggtatctcta tccagtattc cttatgtcca ctaggatcag
    18061 gataggagtg aggcccgggc gctagccgag ctggtccctg gcggactcca cccgagtctt
    18121 cgggccattg gccaagactt caacccccgg cagcgaaatg aaggatggat cggcagggtc
    18181 ggtgcctcat ggggcggagt ggtctggcct cactctcctt ttatatttat acgccggtca
    18241 ctcttattcc ccccagtcac tttcccatag atcattctag cttctcagca gtctctcttt
    18301 tattgtagtt gcattacatc cagccaatgc tcggatagtc gttcgttatt acgttctttt
    18361 gttgctttgt tgccttcata tcccattgaa cttcatatgc ttgttgcttt gagctctggg
    18421 agctcgatag catcatgttg ttcgctcatt ttgctttcct tgttacactc ctggccttag
    18481 gaggcctcac cgtagctaca cagacccggc catgtttggt gtctgccatg aggtataccg
    18541 tgacagcaga tagctgcact tagttgatgt ctcctgctaa ccccggtata ggtctcaatc
    18601 ggatcctgat aacctccaag acatttgtgc gacgaacgta ggcaaggtgt gggccaagat
    18661 cgtggaattt tgcggggatg agagacaatc ggctctggag cagttaaaag acacctgcac
    18721 atctgcaggt tacacaattg gtatgtcttg aacttgggtg atgcttgtga caaagatgag
    18781 agacatttga ctctacttat gcagcataca aaccaacagc ctcgtccgac atcgcgtccc
    18841 attccaccgc tcttttcagc tcaaccaagc ctagctccgt catagctagt tcaaccggca
    18901 tctccacttc cagctctgct ccagacgcca gctctagtct ttgtcccagc actcatccta
    18961 accagaccat ttcgttgggc tcggctgacc gtggcgcgtc agctgctgcg tttgcggctg
    19021 tcgtttttgt cggatttgca gcgacgttat agatttttaa gttagtccgc ttcgtatgat
    19081 atctcagacg aaactctgga cccttgagca tcaatgatgt cgagtacata ttgtgcgcag
    19141 tccgcgtcac tttaaccgcg tcttctccac cggtgtaggc attcgtaggc agctctccga
    19201 aacctgctgg taggcggaaa gctcatacgt aatatatcct agtggggcca aggttgcatg
    19261 ggaatcttga tggtacgtag tcgcagctcg gcggaaacca tatcctgcaa acggatatac
    19321 ggtgtccgag gctcggagct gatttgtaag aaagcacggc agttgctgag ggacgtggcg
    19381 tgaactgaaa gaaaactaca cgtgactgcg ctcgtcgcgc gttcccgcca gccggacaaa
    19441 gattggcggc gcaccagtca gcgggctcgc atgcaaaggg cagcccatct agtccaaaca
    19501 cgaaaattcg cgtggatatc caccgtaacg cgtttgcccc ggcgacatca aatatctcct
    19561 cccatctttc tgcccctccg tcttctcttt cctctcatct ctcatcctcc ctcagctcct
    19621 gtcttcagga cattctttct gtgacgaatt tctcctctca atcctctctt atacatatcc
    19681 aagccttctt ttctctacta caataatatt atatccatat accctttgtt ctagtttatt
    19741 tcttcgttgt ctataacctc actgtccaaa atgtttgtct acaagagagg tgagtgcgag
    19801 ttgcatacat tcccctgttc tggatggaat gaacgcccgt cgattgagca gaatggacct
    19861 tgccacccct gcaactgtca gtgctgactt tgaatctaga cggacgcaaa gaacgcgtgc
    19921 agttcgacaa gatcactgcc cgtgtgtcaa ggctctgtta cggccttgac cccgagcatg
    19981 tcgatgctgc tgctatcacc cagaaggtca tctctggtgt ctaccagggt gtcaccaccg
    20041 ttgaactcga taacctggta ggtttgcagc acttacgata gacagagcaa gtgctgatgt
    20101 gtcgacctag gctgctgaaa ccgctgcgta catgactgtc acacatcccg actacgccat
    20161 cctcgctgcc cgtatcgccg tttccaacct ccacaagcag accaagaagc agttctcgtt
    20221 ggtcatttca gatctctacc actatgtcaa ccccaagaac aaccaacctg cgccaatgat
    20281 atcaaaggag acatacgaaa taatcatgaa acacgccgat gagcttaact cggctattgt
    20341 atacgaccgt gatttcaact acaacttctt cggcttcaag accctggagc ggtcatacct
    20401 gttgcggatc aacggaaagg tggctgagcg tccccagcac ctgctgatgc gtgttgccgt
    20461 tggtatccac ggtagtgaca tcgagaaggc catcgagacc taccacttga tgtcccagaa
    20521 gtacttcact cacgcctccc cgactctgtt caacgctggt actccccagc ctcagcttgc
    20581 ctcttgcttc ctcgtcgaca tgaaggagga cagcattgac ggtatctacg acactttgaa
    20641 gacttgcgct atgatctcca agaccgccgg tggtattggt ctgaacgtgc accgcatccg
    20701 ctctaccgga tcttacattg gtggcaccaa cggtacctcc aacggtcttg ttcccatgct
    20761 tcgggttttc aacaacactg ccagatacgt tgaccagggt ggcaacaagc gtcccggtgc
    20821 ttttgccatc taccttgagc cctggcactc ggatgtcttc gagttcctgg acctccgtaa
    20881 gaaccacggt aaggaggagg tcagagcccg cgatctgttc tatgccctgt ggactccgga
    20941 tctgttcatg aagcgtgttg aggcgaacgg cgactggact ctgttctgcc ccaacgaagc
    21001 ccctggcttg gctgatgtct acggtgacga gttcgacgcc ctctacgaga agtaagtttg
    21061 ttggttcgtg tattctcaac tcatgctaat agtattgtag gtacgagaag gaaggccgtg
    21121 gccgtcgtac catcaaggct cagaagctct ggtacgctat tctggaggct cagaccgaga
    21181 ctggtaaccc cttcatgctg tacaaggatg cttgcaacaa gaagagcaac cagaagaacc
    21241 tcggaaccat ccgtagctcc aacctctgca ctgagatcat tgagtacagt gctccggatg
    21301 aggttgctgt ctgcaacctt gcctctcttg cccttcctac tttcgtcgat gctgctcgcg
    21361 gcgagtatga ctttggcaag ctccacgagg tcgtccaggt cttggtccgt aacttgaaca
    21421 agatcatcga catcaactac taccccgtcc cggaggccaa gaagtccaac ttccgtcacc
    21481 gtcccattgc gctgggtgtc aacggtctgg ctgatgcttt cctcgctctc cgcctgccct
    21541 tcgactcggc cgaggccaga cagctgaaca tccagatctt cgagaccatc tatcacgctg
    21601 gtttgaccgc ctcgtccgat ctcgccaagg agttcggaac ttacgagacc tacgagggat
    21661 ctcctgtctc ccagggtatc cttcagtacg acatgtggga ccgcactccc actgacctct
    21721 gggactgggc tgctctcaag gccaagatcg cccagactgg tgtccgcaac agcttgctgg
    21781 tcgcccccat gcccactgcc agtaccagtc agatcttggg cttcaacgag tgcttcgagc
    21841 cttacacctc caacatctac tcccgccgtg tcttggctgg tgagttccag gtggtcaacc
    21901 cctggctgct gaaggacctg gtcgatctcg gcctgtggtc ggacaacatg aagaaccgca
    21961 tcattgccga gggtggttcc gtccagaaca tccccaacat ccccagtgac atcaaggcgc
    22021 tgtacaagac ggtgtgggag atctcccagc ggacgatcct gcagatggca gcggaccgtg
    22081 gtgcgttcat tgaccagtct cagtccctca acatccacct gaaggagccc accatgggca
    22141 agatcaccag catgcacttt gccggctgga agatgggtct gaagacgggt atgtactacc
    22201 tgcgcacgat ggccgcctct gcgcccatcc agttcaccgt cgaccaggag cagctcaagg
    22261 tcgaggatac caatgtggcc cgcaccaatg ccgcctacaa gaagcgggct gttggcgcgg
    22321 cctccagcac ctactctgct gttccccgcg gccaggctcc ggtcaacgga cacagcgaga
    22381 acggagtcaa cggaatcaac ggctccaaca acggcagccc tcgggctctt gctgcggatg
    22441 cctcctccac tcaggagaac ggcccccagg aggaggacag ccagcaggag agcgaagagc
    22501 gggagaacga catctactcg cagcaggtgc tccagtgcag cattgagaac aaggaggcgt
    22561 gcattatgtg ccagggttag gcatatacct cgtgttttct ctttgtctga tctggtcggg
    22621 tttgattgat ttgtcttggc gtcagggttg taattatatc acgagattga tggatacttt
    22681 ttgcttcttg cgcatggtta tgggaaatga ctgtatttac tgttatgttt ttcttcggta
    22741 taggaattat ttatcttatt atatcatatt atcatttctt aggagcctat tagcctatac
    22801 caatccatga tacgaacata tggatggttt aatgatcccc cgcctgattg ggcatataat
    22861 ccttggccgt ctgcttggtc ttgtccatgc cctcgttggc cttggtcttg gcctgttcgg
    22921 cgtactggga ggcatcggag tctataccaa agtatctccg tcagcattac tccgacatta
    22981 tactccaatc caacaactcc agatgccttc ctccggatca aattggaaag gaaaaagaaa
    23041 ggaaaggaaa ggaaagaaat tgacatactc tgctgccccg tcatctggtt atagtaatcc
    23101 ttgcccttgt tcttggcgtt ttcgaggttc tgcttgatgg aatccat
//
