LOCUS       MCQH01000246           22324 bp    DNA     linear   PLN 27-JUL-2021
DEFINITION  Aspergillus niger.
ACCESSION   MCQH01000246
VERSION     MCQH01000246
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Circumdati.
COMMENT     'Annotated using 1.8.7'.
            ##antiSMASH-Data-START##
            Version      :: 5.1.1
            Run date     :: 2021-07-27 13:34:31
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 696597
            Orig. end    :: 718921
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22324
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[706597:707006](+),
                     [707075:707307](+), [707375:708921](+)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(10001..10409,10479..10710,10779..12324)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..22324
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22324
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            join(521..5498,5557..6045,6113..6228,6281..6715)
                     /locus_tag="ATCC10864_010972"
                     /product="hypothetical protein"
     gene            521..6715
                     /locus_tag="ATCC10864_010972"
     CDS             join(521..5498,5557..6045,6113..6228,6281..6715)
                     /NRPS_PKS="Domain: SAT (150-381). E-value: 2.2e-13. Score:
                     42.1. Matches aSDomain:
                     nrpspksdomains_ATCC10864_010972_SAT.1"
                     /NRPS_PKS="Domain: PKS_AT (1621-1816). E-value: 1.7e-21.
                     Score: 68.6. Matches aSDomain:
                     nrpspksdomains_ATCC10864_010972_PKS_AT.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /codon_start=1
                     /db_xref="PFAM:PF00698"
                     /db_xref="PFAM:PF01575"
                     /db_xref="PFAM:PF08354"
                     /db_xref="PFAM:PF16073"
                     /db_xref="PFAM:PF17951"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 30; E-value: 3.8e-09)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC10864_010972"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_010972-T1"
                     /sec_met_domain="PKS_AT (E-value: 8.9e-21, bitscore: 68.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTATTELHPNPSPSPAGDVPSVAFTLEHGEATAALSVSSAVATTL
                     QPYRASWLADDTISPLSLTLSFLGHLTRQKAPLSAVQTAVRAFETQYLGGIDIHTAVTI
                     LPDALGAKKTALRDYYAAAAYTGQPLSNSPSALFKSAQTGTSRITTIFGGQGTANPSCV
                     RELRSLYTTYRPILTQLMQECGPVLSSLSQRPDTQSYFRGRIIDLNSWLAGATTLNEDF
                     VSAAPVSLPILGLFDLAHYCVISSVLGQTPGQVATSMHAISGHSQGIVVAAAVARADSW
                     TSFYDNARLAVELLFWIGFESHQDAPQLFIAPDLVEQTKEQGHGVPSPMLSVRGLERPA
                     LEKLLAQCNQVLPESRQLHIALINARTNHIVAGPAASLCGLSHILAELQAAGEKDQTRI
                     PFSQRKPAVTHSFLPISTPFHTPYLQAASQRIKERLADRAFSADQLQVPVLHTATGEDL
                     RVNPQSNVIEALVDAITTEPVDFPRLLADATTTHFLVLGAGRLSELVKQIRQGYGQQII
                     AASELKPSSADIGSQADLFAPTLRPAPSSWADAYQPRLVQTANGRLILDTKLSRLLQVP
                     PIITAGMTPTTVPWDFVAAVINAGYFIELAGGGYHTEDEMRVAIEKIAAAIPPGRGITC
                     NLIYVNPKAIAWQTRLIRKLIRQGVPIDGLTIGAGVPSLEVAREYIDDLGIKHISFKPG
                     SVDAINAVLQIADDRPDFPIGLQWTGGRGGGHHSYEDFHAPILATYAEIRKRDNICLVA
                     GSGFGAGDDTYPYLTGQWSVARGYPAMPFDGILLGSRMMLCREAHTSPAVKQLLATTPG
                     VPDGEWEKSYKGSAGGIITVRSEMGQPIHKVATRGVRLWADFDQTLFRHPRPKMVEELA
                     KRKTEIIARLNKDYAKPWFGQDARGQPIDLADMTYAGVLARMVELMYVAHQQRWIHPSY
                     QRLVSDVAVRTLERVAPSVELSLDLLDAPATFLQVLSEKCPAAATQRLHPDDAAFFLRR
                     CQARGQKPVNFIPILDENFETWFKKDSLWQSEDLEAVVGQDPERVCILHGPVAVRYATD
                     KDESAQEILDGIATTHTHAALQDFYQGDLQRVPKVVDATAATSHTQPESSYDVSSLDLV
                     TDNSFSWVRDLLETPTIIREGIRKKNPFRSILAVKPGQKLVVNHAEQRIVLCERSTEQP
                     VISIQSDGTRTISVDLHQPSSFTAAPAVLSLQYKARSTGLSPALEEVVDGRNDRIKTFY
                     RNLWLGEATDPTKDSHSTFHGPEITLTRDLLEDMYRTLGLSPTGIRPQSLPMDIAIVIA
                     WEPLVEPLVCAGVEGDLLRLVHRSNDIDYVPSATPFQVGDVLRSSSQIQSITIEPTGKS
                     IVVKATIERAGGPIAFVTSTFFMRGTYTDYASCFERITEPETMLEVSTPVDEELLRSRP
                     WLQLDEPTTPLVGKTLCFRLETSIDWKDQTTFQTLQTSGTVSLRSWNGKQTPIGRVSFE
                     ARDGKANPVSDFLRRRGQPLVARKPLEVTQELNQASEGVQIPASNAGYSTFSKDFNPIH
                     ISSEFAQYVELPGTITHGMYTSAVVRAVAERCAAQGDLTRFRRWACSFVGMVLPSDQLE
                     VRVQHVAMIEGRLLLNVTAVKAGTDEAVIQAEAEVDQPSTVYVFTGQGSQSPGMGMSLY
                     KSSAAARAIWDAADKFFIETYGWSVLELVRQNPTALTVHFRGKRGRQIKANYMAMTIDA
                     YRADGTLVKEPILPELTPKSTSYTFADPRGLVFSTQFAQPLVLLLERAAVEDLRQRGVV
                     QGDAAFAGHSLGEYGALASFGEFMPFTDLLRVVFYRGLAMQVAIERDDQGRTNFSMAAV
                     NPARVGKFFTEKALRQIVTQIATTTHALLEIVNFNVDGEQYVCAGTLENLHALAAITDT
                     IARSPTGAALAREFTDATTIGNADLASTKLVEQCIAEARQLPAPVTLKRSLATIPLQGI
                     DVPFHSAHLRPGVASYRNFLEERIPKTEVDPQKLVGKWIPNVMGTPFSLSREYVEGVYG
                     LTQSPILKEVLAR"
     aSDomain        971..1663
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC10864_010972_SAT.1"
                     /evalue="2.20E-13"
                     /label="ATCC10864_010972_SAT.1"
                     /locus_tag="ATCC10864_010972"
                     /protein_end="381"
                     /protein_start="150"
                     /score="42.1"
                     /tool="antismash"
                     /translation="IFGGQGTANPSCVRELRSLYTTYRPILTQLMQECGPVLSSLSQRP
                     DTQSYFRGRIIDLNSWLAGATTLNEDFVSAAPVSLPILGLFDLAHYCVISSVLGQTPGQ
                     VATSMHAISGHSQGIVVAAAVARADSWTSFYDNARLAVELLFWIGFESHQDAPQLFIAP
                     DLVEQTKEQGHGVPSPMLSVRGLERPALEKLLAQCNQVLPESRQLHIALINARTNHIVA
                     GPAASLCGLS"
     aSModule        971..6026
                     /domains="nrpspksdomains_ATCC10864_010972_SAT.1"
                     /domains="nrpspksdomains_ATCC10864_010972_PKS_AT.1"
                     /incomplete
                     /locus_tags="ATCC10864_010972"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     CDS_motif       974..1018
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC10864_010972_0001"
                     /evalue="6.20E+00"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ATCC10864_010972"
                     /protein_end="166"
                     /protein_start="151"
                     /score="0.8"
                     /tool="antismash"
                     /translation="FGGQGTANPSCVRELR"
     CDS_motif       1298..1354
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC10864_010972_0002"
                     /evalue="1.70E-03"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="ATCC10864_010972"
                     /protein_end="278"
                     /protein_start="259"
                     /score="11.3"
                     /tool="antismash"
                     /translation="HAISGHSQGIVVAAAVARAD"
     CDS_motif       5378..5434
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC10864_010972_0003"
                     /evalue="1.60E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ATCC10864_010972"
                     /protein_end="1638"
                     /protein_start="1619"
                     /score="17.3"
                     /tool="antismash"
                     /translation="VYVFTGQGSQSPGMGMSLYK"
     aSDomain        join(5384..5498,5557..6026)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC10864_010972_PKS_AT.1"
                     /evalue="1.70E-21"
                     /label="ATCC10864_010972_PKS_AT.1"
                     /locus_tag="ATCC10864_010972"
                     /protein_end="1816"
                     /protein_start="1621"
                     /score="68.6"
                     /specificity="consensus: pk"
                     /specificity="Minowa: trans-1,2-CPDA"
                     /specificity="PKS signature: (unknown)"
                     /tool="antismash"
                     /translation="VFTGQGSQSPGMGMSLYKSSAAARAIWDAADKFFIETYGWSVLEL
                     VRQNPTALTVHFRGKRGRQIKANYMAMTIDAYRADGTLVKEPILPELTPKSTSYTFADP
                     RGLVFSTQFAQPLVLLLERAAVEDLRQRGVVQGDAAFAGHSLGEYGALASFGEFMPFTD
                     LLRVVFYRGLAMQVAIERDDQGRTNFSMAAVNP"
     CDS_motif       5859..5969
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC10864_010972_0004"
                     /evalue="7.20E-06"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ATCC10864_010972"
                     /protein_end="1797"
                     /protein_start="1760"
                     /score="17.9"
                     /tool="antismash"
                     /translation="AFAGHSLGEYGALASFGEFMPFTDLLRVVFYRGLAMQV"
     tRNA            7377..7447
                     /locus_tag="ATCC10864_010973"
                     /product="tRNA-Gly"
     gene            7377..7447
                     /locus_tag="ATCC10864_010973"
     mRNA            join(10001..10409,10479..10710,10779..12324)
                     /locus_tag="ATCC10864_010974"
                     /product="hypothetical protein"
     gene            10001..12324
                     /locus_tag="ATCC10864_010974"
     CDS             join(10001..10409,10479..10710,10779..12324)
                     /codon_start=1
                     /db_xref="PFAM:PF00348"
                     /db_xref="PFAM:PF19086"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Terpene_synth_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 125.9; E-value:
                     2.7e-38)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ATCC10864_010974"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_010974-T1"
                     /sec_met_domain="Terpene_synth_C (E-value: 4.4e-07,
                     bitscore: 23.7, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MFKQYSHILSHKRRRSRGSTINQVLSGAQSEPASEAATVSEPVEV
                     WTHSQVLPEDDEHRKDCFTTLTPRIHKYDHVAQRGSDRFVQDLTASLNLDEPQTSYLSS
                     PVGNYASFLYPECLPERLETVAYLTELGNLHDGKQQGKKTDESAESPRVAARKQLLEKA
                     MSELSDKDKDGHEIIDCYRSNWLVTPEVPTAENCANLDDYVARRRLNAGIDVYWTLMGF
                     AHGTRLGKEDQAVVRDALDAAERTMFFTNDYYSWPKEKRVSKKKPVANVILFLMEHQNM
                     SEEDAVAKAKQLIIDNEHEFVRRREALYQANSDLAPQLRKWMEVLGASLAGIHYWCKNA
                     PRYAVPETTEESEEEEESEEDGSEEEESSSDEDTDDDEEEEEEEEEEKAAPVEVVPEPE
                     ESEEPVEVAVWTPLVTEEETPDVHLDTSALLAPSSYARSISRSTLHSDLLTSLNAWLQV
                     PARPLAFIRQVITELQDSTGMLADVQDQAALRDQRTPAHLVYGPAQCMNSAAYLFVRAA
                     RIVTSLNCPGMLDGLLQELEAHFVGQSWELNWRFSTHCPGETEYLAMVDQKAGASFRLL
                     TRLMQAASMGGATLDLEPFTKVLGRLSQIRHEYLGLLESAASDRSFGEDLDQAKVTYPI
                     VRACNLDPAGRAVIFGIFRQKPAGTVLPIESKRQIVSLVQQTGALQATYDLIRQLGREA
                     MNTLSELETAAEELNPSLRAVVKSLVEVPAPDHL"
     mRNA            complement(join(12602..13737,13799..14132))
                     /locus_tag="ATCC10864_010975"
                     /product="hypothetical protein"
     gene            complement(12602..14132)
                     /locus_tag="ATCC10864_010975"
     CDS             complement(join(12602..13737,13799..14132))
                     /codon_start=1
                     /db_xref="PFAM:PF00171"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 450.9; E-value:
                     6.8e-137)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC10864_010975"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_010975-T1"
                     /transl_table=1
                     /translation="MSQSIPQHPGQRENIETRLFINGEFVPSLSGSKFDLYNPATEELS
                     ASVYEAGPEDVDRAVAAAKAAFPAWSETGALQRAQLLEKWADRLEACADEMAYLDAICM
                     GKPAYSDNFGRIIPLFVRVYAAKALDITGESSLNTPGFVNVSLRQPFGVCGAIVPWNGP
                     VVIMIFKAAAALVTGNTIVIKSSEKAPLSCLVAARCAQEAGIPPGVFNMLSGFGRPCGE
                     AIARHMEIRKISFTGSTTTGRAIQKMAAESNLKSVTLELGGKSPLVIWDDADLSKAVPA
                     AAMSILTNSGQVCVASSRVYVHEAIAPQFLEQLKTTMTEMGKSGHPLIPGTTRGPQADA
                     AQFARVQGYLDLAKQEGVSVYLGGAREGDKGYFVQPTILKDVPEESRLMKEEIFGPVVA
                     VNTFTDEEDVMARANDSEYGLYASIYTRDISRALRAAKKFEAGTVGVNCTSPTMAFDMP
                     FGGWKGSGEGRELSRYATDYWTELKSVLIAL"
     mRNA            15402..17213
                     /locus_tag="ATCC10864_010976"
                     /product="hypothetical protein"
     gene            15402..17213
                     /locus_tag="ATCC10864_010976"
     CDS             15402..17213
                     /codon_start=1
                     /db_xref="PFAM:PF01661"
                     /locus_tag="ATCC10864_010976"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_010976-T1"
                     /transl_table=1
                     /translation="MTGSLPSVLQTLLADSHYFSLQRSVCHHNHHRQHDIASIESMDSW
                     AQFRLMKQLLCVRHPRQSLPSSLLREIDQVLLEERANRLLLDAASIPALPTPSSSSSKP
                     LPATLHLWQGDITTLDGVTAITNAANEQMLGCFQPAHRCLDNVIHARAGPRLREECFHH
                     MDQGQRTLPVGHACATKGYCLPAPYVIHTVGPQLDAGQPVPTAHQRQQLRQCYEAVLDV
                     AEALPASDPRGKSIALCGISTGLFAFPVEEAASIAIQSVLDWLRHHLHTSITNIIFNTF
                     TDTDTAVYQQTLKKMHYPVPSLVPPPRVHGSSLIQAKAWLAAADTILISCGAGISAATG
                     LDYTSTTLFDRHFPAFKQYQLRRLYDTFGRTNRDWPSESVRWGFYFSHLAMVRRWPRSS
                     LYTSLLKWLASRFQPDRVHVRTSNADGLFAAHGLPEAQLSTPQGQYAFLQCLENCRPDA
                     VFPSAPYLDAALPHLDPQTQVVTAQDKIPTCSFCGGAMSICVRAGDWFNERPFAPGETR
                     WHQFREAFLTDLTRNVVIIELGVGLSTPGVLRWENEELIEQGDGRVRLVRAGLGDAVQV
                     PGELAAAQLATSIEGDLQDVVRAIVAP"
     mRNA            join(17821..19600,19657..19934)
                     /locus_tag="ATCC10864_010977"
                     /product="hypothetical protein"
     gene            17821..19934
                     /locus_tag="ATCC10864_010977"
     CDS             join(17821..19600,19657..19934)
                     /codon_start=1
                     /db_xref="PFAM:PF01593"
                     /locus_tag="ATCC10864_010977"
                     /note="SECRETED:SignalP(1-26)"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_010977-T1"
                     /transl_table=1
                     /translation="MPRYNWWYSPLVLGVIYSALVGAVSQHPPREVHRHVLNFQVPSLV
                     TADSLHNVHLDFLDSSFEGHINLFYGDCHTGQGHHEIGHIVIERDAHPERFVWITPADA
                     PHLHCLHAISGSTLLARSDSIPIATRLARRESIADVADVMGPWFDGVAYMQGKEPGKAV
                     VSAAKNSSVAIIGGGISGMMTSLLLNSVGMTNWHIVESSHRLGGRIRTHYLNDSRPDQY
                     QYQELGAMRLPMNITYADTNETLQIQDMRLVLQLADVLNELNADADPALRVNFIPFIQD
                     NPNLPTDTGGVRLPDGRIPTAAQVAANSSLAYTAPPDNASAVADAKAQYMQYAQTDKMG
                     KIREVARNMYRAHKAALEDGFYHWSEAAYMRYALGENADVVDYAAGTANNPIWDGFYDS
                     VYFAATTWFTIDQGMESLVRAFLPHVADKATLGRKVDGLSYNESSGKIAYTWRESPVQI
                     TPERSEEYDYAVVAAPFTKVRMWELPRYSSILSRAISETNYEPACKLALLYKTRFWEHQ
                     EQPIFGGCGTVDIPGVQYVCYPSFNLNGTGPAAVLGAYSHGSPARSVQALKLEDWVALA
                     RRSMVEIHGAIAEEQFTGISHGHCWENDEHQNGAWTHPLVGQQEIFLPAYYQTEFQTIF
                     VGEHTTYTHGWIAAALDSAVRGTTQLLLDLGLVDEAKAIVHEWMGRWIEL"
     mRNA            complement(join(20375..20434,20495..21565,21613..21782,
                     21833..21967,22020..22188))
                     /locus_tag="ATCC10864_010978"
                     /product="hypothetical protein"
     gene            complement(20375..22188)
                     /locus_tag="ATCC10864_010978"
     CDS             complement(join(20375..20434,20495..21565,21613..21782,
                     21833..21967,22020..22188))
                     /codon_start=1
                     /db_xref="PFAM:PF07690"
                     /locus_tag="ATCC10864_010978"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC10864_010978-T1"
                     /transl_table=1
                     /translation="MADKKIDVDCIEHVDQVLVDEAGRIQRLPVPSDDPNDPLNFALWE
                     KTGIVVCCCWFSIMSLSVIGGLGSVLDVFFQMYGAEGHSTNQVVWLSTFPSLFVGIGNY
                     IILPLALVCGRRPVMLIANTVLLGSLIGCALSQNWAQHFGLRILLGFATGATESLLPLM
                     LAEVTFIHQRGTIYGIYWATQNIVTSLLTLASSYEVAALGWRWFYWVFVITVAVGLVLV
                     VFACFETRFQRRPIFVGDHAVITDQYGVTRVLTAPETQEYLASEEGRSYADLDGDTPPK
                     KTYRQMLSAWPRLCPHPLRDVLLTWWQMLETFSSPGIIYATLLSAVILGGSVGVSLTYD
                     TVLQYNYGWGAASIGLINLGGVFGGLGGMLYAGILGDRVIVWLARRAGGVHKPEHHLLL
                     LIFPGLLAVASLLLYGFTASGDATWGGPFMGWTLYQVAFVSTLIRTTSFATEAWEKNPG
                     PALVTVVGTKNIIGFGVSYGLNPMVAKYSYPAAMGILAGVVGGILLLGVPVYFFNPMWR
                     RYISQQRTRDRGQLGGP"
ORIGIN
        1 catcaaggcg accttggccc gcgcccaggc attatcggtg gcgatctggt agtcgtaaac
       61 atagtcgacg atggcctgga tcacagcatc gtagggcttg cgcgagttgt cgtcggcggc
      121 aggaatgaca gtcatgctgg acgggcaatg attggaagat aagagagcgc actagatctt
      181 ctctctcctc ttcctttcaa tgaggaatca tttcttgcct ttcaagtact ttatgaaatg
      241 ttgcattcag ggctgtggcg ggccggatct tgcatcctgg cgtggttcgg gtttcggccg
      301 ccggatgaga ctctgcagca acaccgaatc aattgcggag atgctttggc tgccgaacag
      361 ctttcaatcg gcaggatttg gtctgtctga ctcagctatc gaagcaatgt gagacaacga
      421 agtgagtctt ataatcgacc tcaaaagcta tctatctctg gcctcttctt cttgcccagg
      481 tcgttgttat cccgaccaaa tgtcgcccta gtcacccacc atgactgcga caaccgagct
      541 tcatcccaac ccttcaccct cgcctgctgg ggatgtgcca tccgtggctt ttaccctcga
      601 gcatggcgag gccactgccg cactgtctgt gagtagtgct gtggccacca cactgcagcc
      661 ctaccgcgcc agctggctgg ccgacgacac catctctccc ctcagtctaa cgctgtcctt
      721 cctcggccat ttgacccgcc aaaaggcccc tttatcagca gtccagaccg ctgtgagggc
      781 ctttgaaact cagtatctcg gaggcattga catccacacg gctgtcacta tcctgccaga
      841 cgcccttggt gccaaaaaga ctgccctgcg agattactat gccgccgcag cctataccgg
      901 tcagccctta tccaactcac ccagtgcctt gttcaaatcc gcccagacag gcacctcacg
      961 catcacaaca atctttggcg gccaaggaac ggccaatcca tcgtgtgtgc gcgagttacg
     1021 gtctctctat accacctacc gccccatact cactcagctc atgcaagaat gtggccctgt
     1081 cctgtcctct ctgtcccagc gcccggacac acagtcctac tttcgcggtc gtattatcga
     1141 cttgaattcc tggctggccg gcgcaacaac cctcaatgag gactttgtca gcgctgcgcc
     1201 tgtcagcctg cccattctag gactcttcga cctggcccac tactgcgtca tctccagtgt
     1261 tttgggtcag acccccgggc aagtggctac ttcgatgcat gccatctctg gccattccca
     1321 gggcattgtt gttgccgctg ctgtggctcg tgccgactcg tggacatcgt tctacgacaa
     1381 cgcccggctg gctgtcgagc tgctgttctg gattggcttt gagagtcacc aagatgcgcc
     1441 tcagttgttc atcgcgcccg accttgttga gcaaaccaag gaacaagggc atggagttcc
     1501 ttcgccaatg ctctccgtgc gaggacttga gcggccagca ctggaaaagc ttctcgccca
     1561 gtgtaatcag gttctccctg agtcgcgcca gctgcatatc gccctcatta atgcccgcac
     1621 aaaccacatc gtcgctggtc ctgcagcgtc actgtgcggt ctcagtcata ttctcgccga
     1681 gctgcaagcc gctggggaga aggatcagac tcgcatcccc ttcagccaac gcaagcccgc
     1741 cgtcacgcac tccttcctcc ccatcagcac tcctttccat accccctacc tgcaggcagc
     1801 ctcccagcgc attaaggagc ggcttgccga tcgcgcattt tccgcagacc agctacaagt
     1861 tcctgtcttg cacaccgcga cgggtgagga tctacgagtt aaccctcagt ccaatgtcat
     1921 tgaagccctc gtggatgcga tcaccaccga gcccgttgac ttcccccgtc tgttggccga
     1981 cgcaaccacc acccactttc tcgttctcgg ggctggtcgc ctcagcgaat tagtcaagca
     2041 aatcagacaa gggtatggcc agcagatcat cgccgccagc gagctcaagc cttccagtgc
     2101 cgacatcggt agccaggctg acctctttgc accaaccctc cgcccggctc cttcatcctg
     2161 ggcggacgcc tatcaacctc gcctggtgca aacagccaac ggccggttga tcctcgatac
     2221 gaaactcagt cgcctgctgc aggtaccccc gatcatcacc gcgggtatga cgcccactac
     2281 cgtgccctgg gacttcgtgg cagctgtcat caacgctggt tattttatcg agctggccgg
     2341 cggaggctac cacaccgaag acgagatgcg ggtcgccatc gagaagatcg ctgccgccat
     2401 tcctcctggc cgcggcatta cctgcaatct catctacgtc aatcccaagg cgatcgcctg
     2461 gcagacacgg ctgatccgca agctcatccg ccaaggagta cccattgatg ggcttactat
     2521 cggtgccggt gtgccgtcgc tcgaggttgc tcgcgagtac atcgacgacc ttggcatcaa
     2581 gcacatctcc ttcaagcctg gatcggtcga tgccatcaac gctgtgctgc agatcgctga
     2641 tgaccgaccc gacttcccca tcgggctcca gtggaccggt ggccggggag gcggccatca
     2701 ctcgtatgag gacttccacg cgcccatcct ggccacctac gcggaaattc gcaagcgtga
     2761 caacatctgc ctcgttgccg gcagtggatt tggtgctgga gatgatacct acccttacct
     2821 gaccggccag tggtcagttg ctcggggcta ccccgccatg ccgtttgacg gtattttgtt
     2881 gggcagccgc atgatgctct gtcgcgaagc ccacaccagt ccagcagtaa agcagctgct
     2941 cgccaccaca cctggtgttc ctgatggcga gtgggagaag agctacaaag gcagcgctgg
     3001 cggcatcatt acagttcgat cggaaatggg ccagcccatc cacaaggtgg ccacgcgagg
     3061 agtccggctg tgggccgact ttgaccagac gctgttccgc caccctcgtc cgaagatggt
     3121 ggaggagctg gccaagcgca agactgaaat cattgcccgg ctgaacaagg attatgccaa
     3181 accctggttt ggtcaggatg cccgtggaca gccgattgac ctggcagaca tgacttatgc
     3241 cggagtgctg gcccgcatgg ttgagctgat gtatgtggcc catcagcagc gctggatcca
     3301 tccgtcatac cagcgcctgg tgtcagatgt ggcggtacgc accctcgaac gtgtcgctcc
     3361 gtccgtggaa ctgagcctcg atctgctgga tgcaccagct actttcctgc aggtgctgtc
     3421 cgagaagtgt ccagctgctg ccacgcaacg cctgcatccc gacgatgcgg ctttcttcct
     3481 gcggcgctgc caggcgcgtg gccagaagcc tgtcaatttc attccgattc tggacgagaa
     3541 cttcgaaaca tggttcaaga aggattcgtt gtggcagtca gaggacctgg aggccgtcgt
     3601 agggcaggat cctgagcgcg tgtgcatctt gcatggccct gtcgccgtcc gctatgccac
     3661 cgacaaggac gagtcagccc aggagatcct cgacggcatc gcgaccactc atacccacgc
     3721 ggcgctgcag gacttttacc agggtgatct ccaacgagtg cctaaagtcg ttgatgcaac
     3781 tgccgccacc tcccataccc agcccgaatc ttcgtatgat gtgagctccc tggatctggt
     3841 gacagacaac tcttttagct gggtacgtga ccttctcgag acgcctacta tcatccgcga
     3901 aggcatccgc aagaagaacc cattccgcag catcctggcc gtaaagccag gtcagaagct
     3961 ggtcgtcaat cacgcggagc agcgcatcgt actctgtgag aggagcacgg aacagccagt
     4021 gatcagcatt caaagcgatg gtacccggac catttctgtg gaccttcatc agcccagcag
     4081 ctttaccgct gcccctgcag tcctctcact ccagtacaag gctcgttcca ctggactctc
     4141 tccggcgctg gaggaggttg tagacggacg caatgaccgc atcaagacct tctaccgcaa
     4201 cctttggctg ggagaggcga cagaccctac caaggatagc cactccacct tccacggacc
     4261 tgagataacc ctcactcgcg acctgctcga ggacatgtac cggactttgg gtctttcgcc
     4321 gacgggcatc cgaccgcaat ctctgcccat ggacattgcc attgtgatcg cctgggaacc
     4381 gctggtcgag ccgcttgtct gcgcgggagt tgaaggggat ctgctgcgac tcgtgcaccg
     4441 ctccaacgac attgactatg tgccctccgc tacacctttc caggtcggcg atgtcctgcg
     4501 ctcgagtagc cagatccagt ccatcaccat tgagccgacg ggcaagtcga tcgttgtgaa
     4561 ggccaccatt gagcgggccg gaggacccat cgccttcgtc acctccacct tctttatgcg
     4621 cggcacctac accgactatg cctcctgctt tgaacgcatc accgaaccgg agaccatgct
     4681 cgaggtctct actcccgtag atgaggagct gctgcgatcc cgaccgtggc ttcagttgga
     4741 tgaacccacg accccgctcg tcggcaagac gctctgcttc cgactggaga catccatcga
     4801 ctggaaggat caaacgacct tccagacact tcaaacgagc ggtactgtct ccctccgctc
     4861 ctggaacggc aagcaaacgc ccatcggtcg ggtctccttc gaagctcgcg acggcaaggc
     4921 caatccggtg tcggacttcc tacgtcgacg tggtcagcca ctggtcgctc gcaagccgct
     4981 tgaggtcact caagagctaa accaggcctc ggagggcgtg cagattcccg catccaacgc
     5041 gggctacagt accttctcca aggacttcaa tcccattcac atctcgtctg agtttgcaca
     5101 gtatgttgag ttgcctggca ctatcactca tggcatgtac acgtcagctg tggtacgcgc
     5161 agtcgctgag cgctgtgcgg cgcagggtga tcttacacgt ttccgccgtt gggcctgctc
     5221 gtttgtcggc atggtgctgc cgagcgatca gctggaagtg cgcgtacagc acgtcgctat
     5281 gattgaggga cgattgctgc tgaacgtgac ggccgtcaag gctgggacag atgaagcggt
     5341 catccaggcg gaggccgagg tggatcagcc ctcgacggtg tatgtcttta ccggacaggg
     5401 cagccagtcg ccaggcatgg ggatgagcct gtacaaatcc agtgcggctg cccgggccat
     5461 ctgggacgca gcggacaagt tcttcattga gacctacggt atgtaatacc ccttgttttt
     5521 ctgtatcccc tctagcaagc taataatggc actcaggatg gtcggttctt gagctcgtcc
     5581 gccagaatcc aacagctttg acggtgcact tccggggcaa acgcggacgt cagatcaagg
     5641 ccaactatat ggccatgact atcgatgcat acagggccga tggaacgttg gtgaaggagc
     5701 ccatccttcc ggaactcacg cccaagtcca cttcatacac atttgcggat ccgcgcggtt
     5761 tggtgttctc gacgcagttt gcacagcctc tggtcttgtt gttggagcgc gcggcagtcg
     5821 aggatctccg ccagcgggga gtagttcagg gggatgctgc gtttgcagga cactccctgg
     5881 gcgaatatgg agcattggca tcgtttggcg agtttatgcc cttcacggat ctcctgcgcg
     5941 tggtgttcta tcggggtttg gccatgcagg tggccattga gcgcgatgat cagggacgga
     6001 cgaacttttc catggcggcg gtgaatccgg ctcgtgtggg caagtgtgag taaccattga
     6061 tactctcctg cgtggatgtg gggtttaccg tgaatgctga catgcggttt agtcttcacg
     6121 gagaaggcat tgcggcagat tgtgacacag atcgctacga caacgcacgc cctgctcgag
     6181 attgtcaact tcaatgtcga tggcgagcaa tatgtgtgtg ctgggacggt gagttctctt
     6241 tcccccataa cgaggttggt tctttcgctc atgatatcag ctcgagaacc tccatgccct
     6301 ggccgccatc accgacacta ttgcgcggtc tcctactggg gctgctctcg cacgcgaatt
     6361 taccgacgct accacgatcg gtaatgcaga ccttgcatca acgaagctgg tagagcaatg
     6421 cattgcggaa gcacgccaac tccccgcgcc agtgaccttg aagcgcagcc tcgcgacaat
     6481 tcccctgcag ggcatcgacg tgcccttcca ctcggcacac ctgcgaccgg gagtggcatc
     6541 gtatcgcaac ttcttggagg aacgtattcc caagactgag gtggatccgc agaagctggt
     6601 gggcaagtgg attcccaatg taatggggac gccgttctcg cttagtcggg agtatgtcga
     6661 gggggtgtat gggctgacgc agagtccgat cttgaaggag gtgctagcaa gatagagaag
     6721 agcgggaatg tggtgtgggc ctttatgtgt atatgataga ctgtctgacg gttcgtctgt
     6781 gtttcttgtt accttgtagt agttggttgc tgtctacttc tatccttttg gaatacatta
     6841 acaaatcact tcaattatca cagtacagtc gaataacatt cccgcgctag atgctctcgg
     6901 tataaagata ctactcgagt atgcttgact gggtctttgg gttttgtaga catgttcgtg
     6961 tcttcatgac cctcgtcccc ggtggtcgtg ttgtgcatca atcttggatc aggaagtaga
     7021 aatataagaa acaataatcc agttaagttc gaactactta gttcacttcc aaacaaccat
     7081 agcagaagta ctaggtgttc cctccattat atattttggg gcaactcagg tatactcgta
     7141 ttacgtgtta tgttttttaa agcaggccaa acagcgtgtg catggaggaa ctcggtggct
     7201 ccttgcatcc taatcggacg ggcttgaaag agataggact tcaataccat atgttcagtt
     7261 gttggacttg tggaggtact acacactggg ctcttcatta agagggtcta ctcggagatt
     7321 gactgttagt gtgccaacta cttatagcat aagtattcac tccattatat ataccagcat
     7381 cattggtcta gtggtagaat tcatcgttgc catcgatgag gcccgtgttc gattcacgga
     7441 tgatgcattc ttcttttttc ctctttcctc ttttttttcc ccccccgctc ttccttccca
     7501 gccatgtcca ttcgttcatt ctactatcta tttttgctat ctcgtatctc ctctcctctg
     7561 tctgctgtca atccacctcc aatcatcgcc agccctcaga ctgccgccct gcagctctcg
     7621 ggcctgccga tcgcaaccca ccgctgcagt tcccccactc cacggctcat ctttagtaga
     7681 agtttagacc tgcctatctg tctactttgt gtctttttgg atggctgtct ggttcaacgg
     7741 ttatccacag ttgatcaagt gactctcttg cagtggaaca gctaccctgc acctaactct
     7801 tttctctctc ttcagccact tgccagccaa cggggtccct tctgcctctg atattggagg
     7861 acgacgctat ccatctcgca cttctctcgc tgggtttcgc tggcagcttc acattggccc
     7921 gttgaggttg acatgactaa atacggttca aagtagtgca acgactatct ccttagctta
     7981 ggatggatgc tcagcacgaa tcatcgggcc gggattcgct ggtgatcggg agtcagccga
     8041 ggggaggaat gacgagcttc cctggaagtg ccatcatcaa ccttggtggg aggggcaaac
     8101 cagaggagga aacgacaaac gagtaaggca aagcaaaggc aatgcaatgc aatgcgagaa
     8161 ccaaagcaca gtcagtggat tccaccctca cagagggaga aagagaacaa aactcaccag
     8221 agtaaggcaa tgatccgcaa accaaaggtc caatgggaaa cccgacggag aattaacaac
     8281 gcccggttcc accgtaaaga tgtcaggttg attgccttgg agggggaccc tctcttgtcc
     8341 tcttgctgta tctcccagaa cttcttggat ttacccactg tggaaaaagt gatgctatct
     8401 cgggacaatg aggaccctct tggcccgagc gtttgcagcc tgcagagatt gtcgctggga
     8461 tcgctggcag aaactctact tctctcctac aataactttt ttcttctttt atcttttcaa
     8521 tcatcttgga gggaaactaa acttaaacat gggaatagac tttagattga tgcccagcca
     8581 caatactact caagtttatg tagctgagaa aatcataatg tgactgggga tgggaggcta
     8641 aacagagaga tcgcaccatc tgcactcatg gtatgactgt accctctcca agcgatggta
     8701 acgagggcaa ccacaaccgc ccatttgaac agtgactgtg ccagtgtcag tgccctcaag
     8761 agtctttgcc gcgatcgcga tggcgtcgat tccaaccaaa ttgttatgct ttctccctct
     8821 cgggcaggtg gggccgttgc gtaactcgga attctgattg catcgcgaaa ccgaaaatat
     8881 tccccaaagc aaaaggtgtg agtgagtgat ggatcgatgg cagtggaagt gtaaaaagta
     8941 gtgactatca agaagttgtc gatcctgcgg agtctatctc ctctcccaga ctactttgtg
     9001 tactactttt ttttactacg tatacttcct agtgctgcct gccatgtcaa cccctccctc
     9061 cgatcatcat cctttctcct gactagatac tgtagacttg ttgactgcct aatcaactga
     9121 aaacgaacta actacttggt agtctgtctt gatagtcttt cgtagtcttc tgcaccactc
     9181 cgatctctgc tcgccagcca ccgggacagg cgatatttgc aaggcaattt ggcccctcta
     9241 cgaacctact ttcgcccgac aagttgaaca tgaaaaatca aacagaaaaa tattcgcccc
     9301 cgcggcggac agatgaattc tttcgcacct tcggagacaa aacatcgtca tatctgctgg
     9361 tggacatgcg ttggcccaat aagaaggaca gccagcagcg cgtcgaggat gaagcggtga
     9421 agggcaaagc gatggagatc cacatcgggc aagccgtgga ggtgaagcta aaaaccctaa
     9481 cggcactaag aagacgcaga atgatcagaa tcctccatcc cagcagctaa tggacccacg
     9541 aactgctgta gccgcaagac agctgccgtt gtgtcgccaa tcagcgagct ttcggccgcg
     9601 tagcttgcat cccgtccact cggcagcttc tcaactcctc cctcttcgtt tgcttttttt
     9661 cgctgctact cactgcttct cggggaccaa ctggaggtcc atgctgtttt ccctttcgat
     9721 aaggatgtga aaatttttct tgttggtcag accatgacgc cgacaccaat ctggaggggt
     9781 ggacatcttg cgcatgagcc agcgatctca aattgctatt aaagactcca tctggttcct
     9841 cttctgctcc ctctttctct cttccctttc ttccttttca acttatctcg cgtcgatcgc
     9901 gttgtgaaat atctttatat tgtgaccgca ttgctggtcc tgtatcacta ctcttattac
     9961 ctaccttttt ctttcaattg ttctgttgtg aatcatccca atgttcaagc agtactccca
    10021 catcctgtcc cacaagaggc gtcgcagcag gggaagcacc atcaaccaag tcctgtcggg
    10081 cgctcagtcg gagcctgcat ccgaagcagc cactgtcagc gagcccgtcg aagtatggac
    10141 gcactcgcag gtgctgcccg aggatgatga gcatcgcaag gactgcttca ccaccctgac
    10201 cccgcgcatt cacaagtacg accatgtcgc ccagcgcggc agcgatcgct tcgtccagga
    10261 cctgacggca tcgctgaacc tggatgagcc ccagaccagc tacctttcct cccccgtcgg
    10321 caactatgcc agcttcctct acccggagtg tctgcccgag cgtcttgaga ctgtcgctta
    10381 tttgacggaa ctgggcaatc tgcatgatgg tatgtgaaac cccattaatt atcattacca
    10441 tctcctggca tggctcggac ccaccactga cgtcttaggc aaacaacaag gcaagaaaac
    10501 cgatgaatcc gccgaatccc cccgtgtcgc cgctcggaag caactgctgg aaaaggccat
    10561 gtcggagctg tcggacaagg acaaggacgg ccacgagatc atcgactgct accgcagtaa
    10621 ctggctggtc accccggagg tccctacggc cgagaactgc gccaacctcg acgactatgt
    10681 cgcccggaga cgcctcaatg cgggcattga gtaagtcatc ttcacatcct ccctgcatag
    10741 ctatccatat agaatggatt gctaacaccg gataccagcg tctactggac cctcatgggc
    10801 ttcgcgcacg gcactcgtct cggaaaagag gaccaggcgg tggtgcgcga cgcactggat
    10861 gccgccgagc gcaccatgtt cttcaccaac gactactaca gctggcccaa ggagaagcgc
    10921 gtctccaaga agaagcccgt cgccaacgtg attctcttcc tcatggaaca ccagaacatg
    10981 tccgaggagg atgccgtcgc caaggcaaag cagctgatca tcgacaacga gcacgagttt
    11041 gtgcgccgtc gcgaggcgct ctaccaggcc aactcggacc tggcaccaca gctccgcaaa
    11101 tggatggagg tgctgggcgc ctccctggct ggtattcact actggtgcaa gaatgctccg
    11161 cgctatgcgg tccctgaaac cacagaggag agtgaagagg aggaggagtc cgaggaagat
    11221 ggctctgagg aggaagaatc ttcctctgac gaagacaccg acgacgacga ggaggaagag
    11281 gaagaggaag aggaagaaaa ggctgcaccc gttgaggtgg tgccggaacc cgaggagagc
    11341 gaggaacccg tggaggtggc tgtctggact cccctggtta ccgaggagga aacccccgac
    11401 gtgcatctgg atacctctgc cctgctggcc cccagcagct acgctcgctc gatttcccgc
    11461 agcaccctgc atagtgatct gctcacatct ctgaatgcct ggctgcaggt ccccgcccgc
    11521 ccgctggcct tcattcgcca ggttatcacc gagctgcagg actcgaccgg catgctggcc
    11581 gacgtgcagg accaagccgc gctgcgcgac cagcgcaccc cggcccacct ggtgtacgga
    11641 cccgcacagt gcatgaacag tgcggcgtac ctgtttgtgc gcgccgctcg catcgtcacc
    11701 agcctcaact gccccggcat gctggacggg ctgctgcagg aactggaggc gcactttgtc
    11761 ggccagtcgt gggagctgaa ctggcgcttc tcgacccact gccccggcga gaccgagtat
    11821 ctggccatgg tggaccagaa ggccggcgcc agcttccgtc tgctgacgcg cctcatgcag
    11881 gcggccagca tgggcggcgc gaccctggac ttggagcctt tcaccaaggt gctgggtcgg
    11941 ttgtcgcaga ttcgccacga gtacctgggt ctgctggagt ccgcggctag cgaccgctcg
    12001 ttcggcgagg acctcgatca ggccaaggtg acgtacccca tcgtgcgggc ctgcaacctg
    12061 gaccctgcgg gccgggcggt catctttggc atcttccgcc agaagccggc gggcacggtc
    12121 ctccccatcg agagtaagcg ccagatcgtg tcgctggtgc aacagaccgg ggcgctgcag
    12181 gccacctacg acctgatccg gcagctgggc cgcgaggcca tgaacacgct gagcgagctg
    12241 gagacggcgg cggaggagct gaacccgtcg ttgcgcgcgg tggtgaagtc tctggttgag
    12301 gtgccggccc cggatcacct ataaaagaaa tttgatacct ttgacggaga cgatgcatgg
    12361 tggttgatac gatgatgatg acgatgatga cgatgacact ccttgtttct ctaatgtcta
    12421 catgtctact ttcctttggc gttttctgtg atgatgattt acgagacttt ccttgatgta
    12481 cggctatgag atgatatgat taatgacgat tatattcaag cattcgaacg cctgccttgt
    12541 aaacatgtag aaagaagagt cttattctca gcagacagtt ttatcgctac aacattatga
    12601 actacaaggc aatcaacacc gactttagct cggtccagta gtctgtcgca tatcgactca
    12661 gctctcgtcc ctctccactg cccttccagc ccccaaatgg catgtcaaac gccatggttg
    12721 gactggtgca attgactccc acggtgccgg cctcgaactt cttggctgcc cgcagcgccc
    12781 gcgagatatc ccgcgtgtat atactggcat acagcccgta ctcgctgtcg ttggcgcgtg
    12841 ccatcacgtc ttcctcgtcg gtgaaggtgt tgacggccac cacgggaccg aaaatctcct
    12901 ccttcatcaa gcgcgactcc tccggcacat ctttcaggat ggtcggctgc acaaagtacc
    12961 ctttgtcgcc ctcgcgcgca ccgcccaagt acaccgagac accttcctgc ttcgccaggt
    13021 ccaggtagcc ctgcacgcgc gcaaactggg cggcatcggc ctgcgggccg cgcgtggtac
    13081 ccgggatgag agggtggcca ctcttgccca tctccgtcat ggtggtcttg agctgctcga
    13141 ggaactgagg ggcaatagcc tcgtgcacgt agacccgcga gctggcaacg cagacctggc
    13201 cggaattggt gaggatggac atggcggcgg ccggcacggc cttgctcagg tcggcatcat
    13261 cccagatcac cagcggggac ttgccgccca actcgagggt gacgctcttg aggttcgatt
    13321 cggcagccat cttctggatg gcgcgacccg tggtggtcga gccggtgaag gaaatcttgc
    13381 ggatctccat gtgacgggca atggcctcgc cgcaagggcg accaaagccg ctaagcatgt
    13441 tgaagacacc cggggggatg cctgcttcct gagcacagcg agcagccacc aggcaactca
    13501 gaggggcctt ttcggaggac ttgatgacga tggtgttgcc ggtgactaag gccgcggcag
    13561 ccttgaagat catgatcacg acggggccat tccaggggac aatggcacca caaacgccaa
    13621 agggttggcg caagctgaca ttgacgaagc cgggagtatt caaggaggat tcgccagtga
    13681 tatcaagggc cttggcagca tagacccgca cgaagagggg tatgatgcgg ccgaagtctg
    13741 ggtttggtca tgagttagac atgtctgtct gataggaatg tcgagggaat gagcttactg
    13801 tcactgtaag cgggtttgcc catgcaaatg gcatcaaggt aggccatctc atcggcgcat
    13861 gcctccagac gatcggccca tttctccagt aactgggccc gctgcagggc tcccgtttcc
    13921 gaccaggctg ggaaggcagc tttggcggct gcaacggcgc gatcaacatc ctcgggaccg
    13981 gcttcgtaga ccgaggcact gagctcctcg gtggccgggt tgtacagatc aaacttggac
    14041 ccggagaggg aggggacaaa ctcgccgttg atgaagaggc gagtctcaat gttctcccgc
    14101 tggccgggat gttgggggat ggattgagac atgatgataa caactcaatc aagtgaatga
    14161 agagggaata gacgtgagta ttgacaggca ggagagcaag agggccatga tgaccgggtt
    14221 aatatacgta aatcaaagga tattaggcca accgcagcat gaggggttac gatggctcgg
    14281 cctctgcact agtgcactgg tgtaaccgat tcctcctatg agagtcccaa agcaaattcg
    14341 tatccctgga agatcgtcat ccgtggctcc atgatcgagg agctctgacg ttccagatgt
    14401 ttttggatgc tgtcatggga tgagagttgt ttgccgttct ctgagacagc ttgacagggg
    14461 agagagcctg ctgctgactg ccgtgccacc cgcatgttag ccagtcacta gtcactagct
    14521 attccgcatg cgggatagag tttcaagcac acgaagatct cgcccccaag ctactcatag
    14581 ctactatggt acattatgct gacggtctgg atgtatggcc tggctcgtct caagtggggc
    14641 gatgagggct gaagtatgag aagtgagttg ttcgatggaa atgatatatt agtactaata
    14701 gccatccctt gatgtgggac tgagacgcag actgaattgc gatgtccttc attgttcaga
    14761 gggagcacag aagtcctgga tggttgcaca attcagccgg tataattgcc ttctggcatg
    14821 agtggttgaa tgactccttg cgacagcgtc atcactatga ttgttaagtg tcatcctgtc
    14881 atcccctcga gtggcggaga tagggacgga tatcggagtt atcgtatccg ggaataatgg
    14941 aggttgtctc gacctgttcc atcaggctat aatattggta ctaagatgaa agatgatgag
    15001 gtgtaaatgc tgcagtcaga aaaaaaggaa tgtgactagc catctttgtt tctttatgcc
    15061 agcattgccg atgattctgg ttataattat gttggccttg tccatcacgg cggaatttcc
    15121 ccatgagtgg ataccacctt cccattccgg aaatatgtcc cgtctagaca aacagtgcaa
    15181 atgtaacata cagtgtttcc acaaaaatac atggtatttt gcattatgga caaacagaac
    15241 aaaccagata aacccgctca atgccaataa tatggaaaga tcgaagggga atcgatgagg
    15301 gaaagagagc tacaaaagac ccccaatacc cccctgaatt aagatgggaa ctctactcga
    15361 gatgtatctc ttattaaaac tgtcaaatat ctctgtcagt catgactggc tcactaccgt
    15421 cagtcctgca gaccttactg gctgattccc actacttctc cctgcagaga tccgtctgcc
    15481 accataacca ccaccgccag catgacatcg cctccatcga atccatggat tcatgggccc
    15541 agttccgtct catgaagcag ctgctctgtg tcaggcatcc tcgccagtct cttccatcct
    15601 ccttactccg ggagattgat caggtgttgc ttgaggaacg tgccaatcgc cttcttcttg
    15661 acgctgcttc cattccagct cttccaactc catcatcatc atcatcaaag cctctccccg
    15721 ccacgctcca tctgtggcaa ggagacatta ccacgttgga tggcgttact gccatcacca
    15781 atgcggccaa cgagcagatg ctgggatgtt tccagccggc ccatcgatgc ctggacaatg
    15841 tcatccatgc ccgggcaggt ccccgcttgc gcgaagaatg tttccaccac atggatcagg
    15901 gacagcgcac cttgcccgtc ggccacgcat gtgccaccaa aggatactgt cttcctgccc
    15961 cctatgtgat tcacaccgta ggccctcagc tggacgcggg acagcctgtg cccaccgcgc
    16021 accaacgtca acagctgcgg caatgctatg aggccgtcct ggatgtcgca gaagctctgc
    16081 ctgcatcgga tcctcggggc aagtccattg ctctttgtgg catctcgacc ggactgtttg
    16141 cctttcccgt ggaggaggct gcatccattg ccattcaatc cgttctcgac tggctgcggc
    16201 accatctgca cacctccatc accaacatca tcttcaacac cttcaccgac accgacacgg
    16261 ccgtctacca acagacactc aaaaaaatgc actatccagt tccttcccta gtgccacctc
    16321 cccgggtcca tggatcctcc cttatccaag ccaaagcttg gctggctgct gccgatacca
    16381 ttttgatcag ctgcggagcc gggatctcgg cggccactgg actcgactat acctcgacca
    16441 ctctgttcga tcgccacttc ccggcattca agcaatacca gctgcgacgg ctgtatgaca
    16501 cctttggccg caccaaccgt gactggccat ctgagagcgt ccgctgggga ttttacttct
    16561 cccatctggc catggtgcgt cgctggcccc gctcgtccct ctatacctcg ctgctaaaat
    16621 ggctggcatc acgttttcaa ccggatcggg ttcacgtgcg gacctccaat gcagacggac
    16681 tctttgcagc tcatggactg cccgaagcgc agctctccac accccagggc cagtatgcct
    16741 tccttcaatg tctggaaaac tgccgtccgg atgctgtctt cccatcggca ccgtatcttg
    16801 acgctgccct gccgcatctg gatccacaga cacaggtcgt aacggcgcag gacaaaatcc
    16861 caacatgttc attctgtggt ggcgccatgt cgatctgtgt tcgggcggga gactggttca
    16921 acgaacgacc cttcgctccc ggcgaaacgc gatggcacca attccgcgag gcctttctca
    16981 cggatctgac acgaaacgta gttattattg agctgggtgt cggcctttcc acgccagggg
    17041 tgctgcggtg ggagaatgag gagctgatcg agcagggcga tggacgcgta cggctggtgc
    17101 gcgcgggttt gggcgatgcc gtgcaggtcc ctggggagct ggctgctgcg cagctggcca
    17161 ccagcatcga aggggacttg caggatgtgg ttcgggcgat agtggctccg tagactggcc
    17221 aagtgacatg tagatgtgat acatctaatt tgctaaagcg attctttgct ggactttgct
    17281 gtttcttcct gacatggtct atatatttct ccgggtacgg tagtccatca gctacacatg
    17341 cgtataacta ccaaagcagt tttctgtcct gcgcgatggc cttccatcga atggaattgt
    17401 gaccattccg tgaaatagcc aggaggatgt gatccaagtc gggttagtcc cgtcgttctc
    17461 tccgcaccag gcaatgtggc tgtcgaagat cggcttttgg cgcaaatttc cgagcggcaa
    17521 ttattgaaac tagttcggcg ggtcaccacc aagtttggcc ttcagaaata gacacgcaaa
    17581 tggcagcgtg tcagactgca ataaatcaac ggcacccata aacccctgta tctgcaggat
    17641 cctcaattat tgatatcttc ttatgtagac acacatcatg tagggtaatt gaaagactga
    17701 gttagtgatg agaactcggt ggtaatctgg aatggcgccg gtataaaatc atgcatggca
    17761 tccgtataat cacccctgtc atccgggcag agtgtgctga cctcaatacc tcggcgcgcc
    17821 atgcctcgct acaactggtg gtattctccg cttgtcctgg gcgtgatata tagcgccttg
    17881 gtaggcgcag tttcccaaca tccccccaga gaggttcaca gacatgtcct gaattttcag
    17941 gtgccgagcc tggtcaccgc agactccctg cacaacgttc atctggactt tctggacagt
    18001 agctttgaag gtcatatcaa tctgttctac ggggactgcc ataccggcca ggggcatcat
    18061 gagatcggcc acattgtcat cgagcgtgac gctcatccag agcgcttcgt ctggatcaca
    18121 cccgccgatg cgcctcatct gcactgcctc cacgccattt ctggatcgac tctgctcgct
    18181 cgttccgatt ccattccaat tgccacccgc ttggctcgtc gggaaagcat cgccgacgtg
    18241 gctgatgtga tgggcccctg gtttgacggc gtcgcgtaca tgcaaggcaa ggaacccgga
    18301 aaggctgtgg tgtcggcagc aaagaactct tccgtggcta ttatcggcgg tggcatctcc
    18361 ggaatgatga caagtctgct gctcaactct gtcggcatga ccaattggca cattgtggag
    18421 tcatcccatc gactaggtgg ccgcattcgc actcactatc tgaacgattc gcggcccgat
    18481 cagtaccaat accaggagtt gggggctatg cgccttccca tgaacatcac ctacgccgat
    18541 accaacgaga cactccagat ccaggacatg cgactagtcc ttcagttggc cgatgtcctc
    18601 aatgagctca acgccgacgc tgatccagcg ctgcgagtca acttcattcc tttcatccag
    18661 gataatccga atcttccgac tgacacggga ggtgttcgtc tgccagacgg ccgaatccct
    18721 actgcagccc aggttgccgc caactcgtcg ctggcataca cggcgcctcc cgacaacgcc
    18781 agtgccgttg cggacgccaa agctcagtac atgcagtacg cccagacaga caagatgggt
    18841 aagatccggg aggttgctcg caacatgtac cgcgcacaca aagcggctct ggaagacggg
    18901 ttctaccact ggtcggaagc cgcatatatg cggtacgcgc tgggggagaa cgcagatgtc
    18961 gtcgactacg ccgctggcac ggccaacaat cccatttggg atggattcta cgatagtgtc
    19021 tactttgcgg ccaccacctg gtttaccatc gaccagggga tggagtctct ggtgcgagca
    19081 ttcctaccgc acgtcgcaga caaagccacc ctcgggcgga aagtggacgg gctctcgtac
    19141 aacgagagct cgggcaagat tgcctacacc tggcgcgaat ctccggtcca gatcacccct
    19201 gagcgcagcg aagaatatga ctatgctgtc gtggccgcgc ctttcaccaa ggtgcgcatg
    19261 tgggaattgc cgcgatattc gtcgatcctg agccgggcca tttccgagac aaactatgaa
    19321 cccgcctgca agctcgccct gctgtataaa acccgcttct gggagcacca agaacagccc
    19381 atcttcgggg gctgcggcac tgtggacatt ccgggggtgc aatatgtatg ctatccatcg
    19441 ttcaatctga atggtaccgg cccggcggcg gttcttgggg catattccca tggaagcccg
    19501 gcgcggagtg tacaggcgtt gaaactcgag gattgggtcg cattggcacg gcgcagcatg
    19561 gtggagattc acggggcgat tgcagaggaa caattcacag gtaggccgga tcctttgaat
    19621 aagtagccct cagtctcatg cttactgtcc cgataggtat ctcccatggt cactgctggg
    19681 agaatgatga acaccaaaac ggcgcctgga cacaccccct tgttgggcag caagagattt
    19741 tcctgcccgc ctactaccaa accgagttcc agaccatttt cgttggcgag cataccacgt
    19801 atacccatgg ctggatcgcc gcggctctag actccgccgt gcgcgggact acccaactct
    19861 tgctggacct ggggctggtg gatgaggcca aggcgattgt gcatgagtgg atgggtcgat
    19921 ggattgaatt gtaagatata caggtgctca ggagtttaca atctcaagat acaatagttt
    19981 tcttcgttca caattccagg taattaagat tgtgtctggg ctcggatcat agcgaattgg
    20041 gggttctcgg gcagcaccga acagccgacg gtgccgccga agtgcacggt catgccccga
    20101 aggagcagtt gtagatcccc cactttccga ctgtcaacgt agtaatccac gcgtcggtca
    20161 tgtaggaagc cattagagaa gatcagtaga cttgtgttcg tagcgtctgt tttgtatgtt
    20221 tatgacagtt gtagtcagat ccgattatgg caagtctacg ggtatacaat tcagcgagta
    20281 gtgtatcccg atcattttgt attccgagaa cacaatgcag aacattcaaa tatcttgctg
    20341 tacaacatac aaatgagagt gtccatcctt cccattacgg tcctccaagt tgtccccggt
    20401 cgcgtgttcg ttgctggctg atataccgtc tccactgaac ctaagttagc atgactgcat
    20461 ctccgaaaat catcagcaaa agacgggtaa ttaccattgg attgaagaag tagacgggaa
    20521 cccccagcag cagaattcca cccaccaccc ccgccagaat tcccatggct gccggataac
    20581 tatacttggc caccatgggg ttcaaaccat agctgacccc aaaccctatg atgttcttcg
    20641 tccccacgac cgtcaccagc gccggaccag gattcttctc ccatgcttcc gtggcaaacg
    20701 atgtcgtgcg gatgagggtc gaaacgaagg ctacctgata gagcgtccag cccatgaaag
    20761 gccctcccca agtggcatcg ccgctggcgg tgaatccata taacagcagc gaggctactg
    20821 ccaacagccc tgggaaaatc aataagagga gatgatgttc gggtttatga acacccccgg
    20881 cgcgtcgggc caaccaaaca atgacacggt cgcccaaaat ccccgcgtag agcatgccgc
    20941 ccagcccgcc aaagacgccg cctaagttga taaggccaat gctggcggca ccccagccgt
    21001 agttgtactg caagaccgtg tcataggtga gagagacacc gacggacccg cctaagatga
    21061 cagcagagag gagtgtggca tagatgatgc cgggcgagct gaaggtctcg agcatctgcc
    21121 accaggtgag caggacgtcg cgtaggggat gagggcagag gcgtggccaa gcgctgagca
    21181 tctggcggta ggttttcttg ggaggcgtgt cgccgtcgag gtcggcgtaa gagcgaccct
    21241 cttcactagc gaggtattct tgggtttctg gggcagtcag gactcgggtc actccatatt
    21301 gatcggtgat gacggcgtgg tcgcccacga agattggtcg acgctggaac cgcgtctcga
    21361 agcaggcaaa caccaccagc accagtccga cggcgacggt tataacaaac acccagtaga
    21421 accagcgcca ccctagcgca gctacttcat atgagctggc cagcgtcaga aggctcgtca
    21481 cgatgttttg agtggcccag tagatgccat agatggtgcc gcgctggtga atgaaggtca
    21541 cctctgccaa catcagaggg agaagctatg gtaggttaga tcaaccacaa agaggaaata
    21601 cagctgtcgc accgattccg tcgctcctgt agcaaatccc aaaaggatgc gtagcccaaa
    21661 atgctgggcc cagttctgtg acaaggcaca gccgatcaac gaccccagca gaacggtgtt
    21721 ggcgatgagc atcaccggtc gacgtccgca gacaagggct aacggcagga tgatgtagtt
    21781 ccctgacact ggtgagttgc tgacggtagc agagctggaa gagacacctt accaattcca
    21841 acaaatagtg aggggaaagt cgagagccag acaacctggt tggtgctgtg accttctgcg
    21901 ccgtacatct gaaagaaaac atccagaaca gagcccagcc caccaatgac cgagagtgac
    21961 atgatagctg agagaatgag cttggaactt aatagtcaat tgggggaaag ggaacttaca
    22021 gaaccaacaa cagcacacca cgatgcctgt cttctcccac agtgcaaagt tcaaggggtc
    22081 attgggatcg tcgctgggca ccggcagacg ctggatgcga ccagcctcgt ccaccagcac
    22141 ctgatcaaca tgctcgatgc aatcgacatc aatcttcttg tcggccattc tgccggatac
    22201 tcatgcttga acaacaaacg ggtggcatcg cagcgcgcga cggagggttt taagctcgca
    22261 gcttgtgtcc actccccgaa gagactaagc atattttaga gaatgcgggg aagatatggg
    22321 gaat
//
