Identified secondary metabolite regions

KZ851899.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 1.1 NRPS-like,T1PKS 558,350 605,490
Region 1.2 terpene,NRPS,T1PKS 1,214,507 1,286,462 HC-toxin NRPS 100%
KZ851900.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 2.1 NRPS-like 38,841 80,629
Region 2.2 T1PKS 82,110 130,596
Region 2.3 NRPS-like 170,623 211,417
Region 2.4 NRPS 1,202,898 1,248,676
KZ851902.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 4.1 indole 556,704 578,154
Region 4.2 T1PKS,NRPS-like 680,052 733,391 Notoamide NRPS 11%
Region 4.3 NRPS,T1PKS 778,587 849,213 Aureobasidin A1 NRPS 100%
KZ851905.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 7.1 NRPS-like 112,866 155,652
Region 7.2 terpene 326,807 348,116
KZ851906.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 8.1 NRPS 54,676 99,109
Region 8.2 terpene 404,361 425,976 HC-toxin NRPS 100%
Region 8.3 T1PKS 462,029 509,598
Region 8.4 T1PKS 531,374 577,269 Duclauxin t1pks 42%
Region 8.5 NRPS-like 588,471 627,711
Region 8.6 NRPS 658,438 706,188
Region 8.7 T1PKS 751,649 800,043
KZ851907.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 9.1 T1PKS 251,754 300,058
KZ851908.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 10.1 T1PKS,NRPS 42,276 92,287 Melleolides t1pks 100%
Region 10.2 NRPS 132,745 190,064
Region 10.3 T1PKS 718,132 765,679
KZ851909.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 11.1 T1PKS 1 41,060
Region 11.2 NRPS 41,694 93,755
Region 11.3 NRPS-like 672,915 709,092
Region 11.4 terpene 829,729 851,128
Region 11.5 NRPS-like 864,728 908,103
KZ851910.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 12.1 NRPS 183,857 245,161
KZ851911.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 13.1 terpene 13,293 34,788
Region 13.2 T1PKS 75,434 131,709
Region 13.3 T1PKS,NRPS-like 178,269 240,789
Region 13.4 T1PKS,NRPS-like 491,515 544,621 Communesin polyketide 12%
Region 13.5 T1PKS 575,993 624,800
KZ851912.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 14.1 NRPS-like 455,733 498,786
KZ851913.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 15.1 NRPS,T1PKS 17,638 125,130
Region 15.2 T1PKS 212,899 260,664
Region 15.3 terpene 276,280 297,885
KZ851914.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 16.1 terpene 537,361 558,320
KZ851915.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 17.1 siderophore 103,506 115,649
Region 17.2 NRPS-like 126,316 164,190
Region 17.3 NRPS-like,T1PKS 355,060 412,549 HC-toxin NRPS 100%
KZ851916.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 18.1 T1PKS,NRPS 239,058 291,157 Wortmanamide A t1pks 100%
KZ851917.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 19.1 T1PKS 263,450 310,701
Region 19.2 terpene 314,276 336,834
KZ851918.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 20.1 T1PKS 250,873 297,337
Region 20.2 terpene 451,835 473,508
Region 20.3 NRPS,terpene 477,513 524,578
KZ851919.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 21.1 T3PKS 59,844 101,070
Region 21.2 NRPS 264,390 323,409
KZ851920.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 22.1 terpene 70,069 89,171
Region 22.2 terpene 242,445 267,434
Region 22.3 NRPS-like 354,757 398,137
KZ851921.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 23.1 terpene 236,475 257,431
Region 23.2 T1PKS 328,031 369,580
Region 23.3 T1PKS,NRPS 369,980 476,091 Azanigerone t1pks 93%
Region 23.4 T1PKS 511,251 559,576
KZ851922.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 24.1 NRPS-like 20,094 63,887
Region 24.2 betalactone 450,679 479,789
KZ851923.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 25.1 NRPS 171,250 224,487
KZ851924.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 26.1 T1PKS,NRPS 7,093 59,236 Phyllostictine A / phyllostictine B nrps-t1pks 20%
Region 26.2 NRPS 384,320 443,640 Nidulanin A polyketide 75%
KZ851925.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 27.1 NRPS-like 424,793 458,956
KZ851930.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 32.1 T1PKS 61,190 108,681
KZ851932.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 34.1 bacteriocin 10,799 21,489
KZ851935.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 37.1 NRPS-like 80,441 125,571
KZ851936.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 38.1 T1PKS 280,432 322,929
KZ851937.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 39.1 indole 25,349 46,708
KZ851938.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 40.1 NRPS 149,212 205,704
Region 40.2 siderophore 270,855 282,954
KZ851939.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 41.1 T1PKS 268,886 302,354 TAN-1612 t1pks 100%
KZ851941.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 43.1 terpene 204,656 226,979
KZ851942.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 44.1 NRPS,T1PKS 91,357 174,926 Fumonisin t1pks 47%
KZ851944.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 46.1 T1PKS,NRPS 176,038 227,889 Pyranonigrin E polyketide 100%
Region 46.2 NRPS 240,656 288,965
KZ851945.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 47.1 terpene 50,987 72,286
Region 47.2 T1PKS 120,958 164,462 Naphthopyrone t1pks 100%
Region 47.3 T1PKS 215,615 263,797
KZ851949.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 51.1 T1PKS 80,958 127,753
Region 51.2 T1PKS 198,066 236,394 Aflavarin t1pks 60%
KZ851952.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 54.1 T1PKS 11,342 56,681 Yanuthone D t1pks 90%
KZ851953.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 55.1 terpene 19,470 41,486
Region 55.2 NRPS,T1PKS 146,050 193,119 Isoflavipucine nrps-t1pks 12%
KZ851954.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 56.1 terpene 28,348 50,664 Clavaric acid terpene 100%
KZ851955.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 57.1 T1PKS 115,055 163,229
KZ851956.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 58.1 NRPS 35,458 95,413 Aflatrem terpene 17%
KZ851957.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 59.1 NRPS,T1PKS 1 45,372 Wortmanamide A t1pks 100%
KZ851958.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 60.1 terpene 80,883 102,004 Aflatrem terpene 11%
KZ851964.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 66.1 terpene 55,726 78,286
KZ851965.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 67.1 NRPS 57,254 104,797
KZ851966.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 68.1 NRPS,T1PKS 25,961 77,700 Pyranonigrin E polyketide 100%
KZ851967.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 69.1 T1PKS 41,937 89,759 Pyripyropene A terpene-t1pks 25%
KZ851973.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 75.1 NRPS-like 3,760 46,861
No secondary metabolite regions were found in these records:
KZ851901.1 (Aspergillus niger)
KZ851903.1 (Aspergillus niger)
KZ851904.1 (Aspergillus niger)
KZ851926.1 (Aspergillus niger)
KZ851927.1 (Aspergillus niger)
KZ851928.1 (Aspergillus niger)
KZ851929.1 (Aspergillus niger)
KZ851931.1 (Aspergillus niger)
KZ851933.1 (Aspergillus niger)
KZ851934.1 (Aspergillus niger)
KZ851940.1 (Aspergillus niger)
KZ851943.1 (Aspergillus niger)
KZ851946.1 (Aspergillus niger)
KZ851947.1 (Aspergillus niger)
KZ851948.1 (Aspergillus niger)
KZ851950.1 (Aspergillus niger)
KZ851951.1 (Aspergillus niger)
KZ851959.1 (Aspergillus niger)
KZ851960.1 (Aspergillus niger)
KZ851961.1 (Aspergillus niger)
KZ851962.1 (Aspergillus niger)
KZ851963.1 (Aspergillus niger)
KZ851968.1 (Aspergillus niger)
KZ851969.1 (Aspergillus niger)
KZ851970.1 (Aspergillus niger)
KZ851971.1 (Aspergillus niger)
KZ851972.1 (Aspergillus niger)
KZ851974.1 (Aspergillus niger)
KZ851975.1 (Aspergillus niger)
KZ851976.1 (Aspergillus niger)
KZ851977.1 (Aspergillus niger)
KZ851978.1 (Aspergillus niger)
KZ851979.1 (Aspergillus niger)
KZ851980.1 (Aspergillus niger)
KZ851981.1 (Aspergillus niger)
KZ851982.1 (Aspergillus niger)
KZ851983.1 (Aspergillus niger)
KZ851984.1 (Aspergillus niger)
KZ851985.1 (Aspergillus niger)
KZ851986.1 (Aspergillus niger)
KZ851987.1 (Aspergillus niger)
KZ851988.1 (Aspergillus niger)
KZ851989.1 (Aspergillus niger)
KZ851990.1 (Aspergillus niger)
KZ851991.1 (Aspergillus niger)
KZ851992.1 (Aspergillus niger)
KZ851993.1 (Aspergillus niger)
KZ851994.1 (Aspergillus niger)
KZ851995.1 (Aspergillus niger)
KZ851996.1 (Aspergillus niger)
KZ851997.1 (Aspergillus niger)
KZ851998.1 (Aspergillus niger)
KZ851999.1 (Aspergillus niger)
KZ852000.1 (Aspergillus niger)
KZ852001.1 (Aspergillus niger)
KZ852002.1 (Aspergillus niger)
KZ852003.1 (Aspergillus niger)
KZ852004.1 (Aspergillus niger)
KZ852005.1 (Aspergillus niger)
KZ852006.1 (Aspergillus niger)
KZ852007.1 (Aspergillus niger)
KZ852008.1 (Aspergillus niger)
KZ852009.1 (Aspergillus niger)
KZ852010.1 (Aspergillus niger)
KZ852011.1 (Aspergillus niger)
KZ852012.1 (Aspergillus niger)
KZ852013.1 (Aspergillus niger)
KZ852014.1 (Aspergillus niger)
KZ852015.1 (Aspergillus niger)
KZ852016.1 (Aspergillus niger)
KZ852017.1 (Aspergillus niger)
KZ852018.1 (Aspergillus niger)
KZ852019.1 (Aspergillus niger)
KZ852020.1 (Aspergillus niger)
KZ852021.1 (Aspergillus niger)
KZ852022.1 (Aspergillus niger)
KZ852023.1 (Aspergillus niger)
KZ852024.1 (Aspergillus niger)
KZ852025.1 (Aspergillus niger)
KZ852026.1 (Aspergillus niger)
KZ852027.1 (Aspergillus niger)
KZ852028.1 (Aspergillus niger)
KZ852029.1 (Aspergillus niger)
KZ852030.1 (Aspergillus niger)
KZ852031.1 (Aspergillus niger)
Compact view
KZ851899.1 - Region 1 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 558,350 - 605,490 nt. (total: 47,141 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 558349 - 605490:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - mal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_336351: X - mal
Search NORINE for peptide: strict or relaxed

AMP-binding (24..423): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmfvvglask
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

PKS_AT (1161..1455): mal
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 162.6
inactive: 74.8
Methoxymalonyl-CoA: 73.9
Methylmalonyl-CoA: 66.3
Isobutyryl-CoA: 42.7
Propionyl-CoA: 37.3
Acetyl-CoA: 31.3
Ethylmalonyl-CoA: 30.8
Benzoyl-CoA: 29.8
trans-1,2-CPDA: 28.8
CHC-CoA: 27.6
fatty_acid: 18.8
2-Methylbutyryl-CoA: 17.4
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
inactive: 66.7%
Methylmalonyl-CoA: 58.3%


KZ851899.1 - Region 2 - NRPS,T1PKS,terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,214,507 - 1,286,462 nt. (total: 71,956 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 1214506 - 1286462:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk - hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 1235068 - 1286462:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk - hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_347997: pk - hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

PKS_AT (545..864): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 90.8
Methoxymalonyl-CoA: 77.4
Ethylmalonyl-CoA: 60.9
Isobutyryl-CoA: 50.0
Benzoyl-CoA: 49.0
trans-1,2-CPDA: 44.9
Malonyl-CoA: 40.7
inactive: 32.2
Propionyl-CoA: 32.1
2-Methylbutyryl-CoA: 21.9
CHC-CoA: 14.8
fatty_acid: 14.6
Acetyl-CoA: 8.9
3-Methylbutyryl-CoA: 1.8

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 70.8%
Ethylmalonyl-CoA: 58.3%

AMP-binding (2944..3353): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
gltllalfgk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851900.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 38,841 - 80,629 nt. (total: 41,789 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 38840 - >80629:
Polymer prediction:
(ala)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_291813: ala
Search NORINE for peptide: strict or relaxed

AMP-binding (13..412): ala
NRPSPredictor2: ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
ala
Stachelhaus prediction details:
Stachelhaus sequence:
nvwlwnceik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851900.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 82,110 - 130,596 nt. (total: 48,487 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 82109 - 130596:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_227923: pk
PKS_AT (553..868): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 75.9
Methoxymalonyl-CoA: 64.9
Malonyl-CoA: 56.3
Isobutyryl-CoA: 44.4
Ethylmalonyl-CoA: 33.1
Propionyl-CoA: 27.4
2-Methylbutyryl-CoA: 14.7
Benzoyl-CoA: 12.4
trans-1,2-CPDA: 12.1
fatty_acid: 11.8
inactive: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
Methylmalonyl-CoA: 70.8%
Ethylmalonyl-CoA: 66.7%


KZ851900.1 - Region 3 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 170,623 - 211,417 nt. (total: 40,795 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location <170622 - 211417:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_251638: X
Search NORINE for peptide: strict or relaxed

AMP-binding (69..353): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hlsq--t--k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851900.1 - Region 4 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1,202,898 - 1,248,676 nt. (total: 45,779 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 1202897 - 1248676:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_352705: X
Search NORINE for peptide: strict or relaxed

AMP-binding (189..581): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvlevgavvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851902.1 - Region 1 - indole
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 556,704 - 578,154 nt. (total: 21,451 nt) Show pHMM detection rules used
indole: (indsynth or dmat or indole_PTase)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851902.1 - Region 2 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 680,052 - 733,391 nt. (total: 53,340 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location <680051 - 733391:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location <680051 - 726249:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location <693552 - 733391:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_367294: pk
PKS_AT (540..849): pk
minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 73.2
Methylmalonyl-CoA: 72.4
Malonyl-CoA: 64.7
Ethylmalonyl-CoA: 50.6
Isobutyryl-CoA: 43.7
Propionyl-CoA: 43.3
inactive: 25.0
2-Methylbutyryl-CoA: 24.2
trans-1,2-CPDA: 20.0
Benzoyl-CoA: 14.9
CHC-CoA: 12.4
fatty_acid: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 87.5%
Methylmalonyl-CoA: 70.8%
Ethylmalonyl-CoA: 62.5%


M747DRAFT_273675: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (29..418): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hllmyavlik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851902.1 - Region 3 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 778,587 - 849,213 nt. (total: 70,627 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 778586 - 849213:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(phe) + (pk - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_367317: pk - X
Search NORINE for peptide: strict or relaxed

PKS_AT (547..865): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 76.5
Methoxymalonyl-CoA: 69.0
Ethylmalonyl-CoA: 43.4
Malonyl-CoA: 38.3
Propionyl-CoA: 33.8
Benzoyl-CoA: 27.6
trans-1,2-CPDA: 26.0
Isobutyryl-CoA: 24.4
fatty_acid: 19.2
CHC-CoA: 11.8
2-Methylbutyryl-CoA: 2.6
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 62.5%

AMP-binding (2970..3380): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
didmngcvwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


M747DRAFT_292800: phe
Search NORINE for peptide: strict or relaxed

AMP-binding (264..666): phe
NRPSPredictor2: phe
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
phe
Stachelhaus prediction details:
Stachelhaus sequence:
dawmfaatfk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851905.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 112,866 - 155,652 nt. (total: 42,787 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 112865 - 155652:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_313104: X
Search NORINE for peptide: strict or relaxed

AMP-binding (25..443): X
NRPSPredictor2: asp, asn, glu, gln, aad
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
vgefvggagk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851905.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 326,807 - 348,116 nt. (total: 21,310 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851906.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 54,676 - 99,109 nt. (total: 44,434 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 54675 - 99109:
Polymer prediction:
(hydrophilic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_255610: hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (216..620): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvdggggigk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851906.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 404,361 - 425,976 nt. (total: 21,616 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
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zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851906.1 - Region 3 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 462,029 - 509,598 nt. (total: 47,570 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 462028 - >509598:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_329631: pk
PKS_AT (604..882): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 66.3
Malonyl-CoA: 58.3
Methoxymalonyl-CoA: 54.1
Isobutyryl-CoA: 40.1
Ethylmalonyl-CoA: 36.8
Benzoyl-CoA: 29.0
fatty_acid: 28.5
inactive: 16.1
CHC-CoA: 12.6
trans-1,2-CPDA: 11.5
2-Methylbutyryl-CoA: 11.0
Propionyl-CoA: 10.4
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Methylmalonyl-CoA: 58.3%


KZ851906.1 - Region 4 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 531,374 - 577,269 nt. (total: 45,896 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 531373 - 577269:
Polymer prediction:
(mal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_364003: mal
PKS_AT (928..1227): mal
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 88.8
inactive: 41.4
Methoxymalonyl-CoA: 39.2
Methylmalonyl-CoA: 32.7
Isobutyryl-CoA: 25.2
CHC-CoA: 23.3
2-Methylbutyryl-CoA: 22.5
Ethylmalonyl-CoA: 19.5
Propionyl-CoA: 19.4
Acetyl-CoA: 15.9
Benzoyl-CoA: 15.4
fatty_acid: 10.8
3-Methylbutyryl-CoA: 10.8
trans-1,2-CPDA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%


KZ851906.1 - Region 5 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 588,471 - 627,711 nt. (total: 39,241 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 588470 - >627711:
Polymer prediction:
(pro)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_364024: pro
Search NORINE for peptide: strict or relaxed

AMP-binding (4..407): pro
NRPSPredictor2: pro
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
pro, pip
Small clusters prediction:
pro
Single AA prediction:
pro
Stachelhaus prediction details:
Stachelhaus sequence:
dmfflativk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851906.1 - Region 6 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 658,438 - 706,188 nt. (total: 47,751 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 658437 - 706188:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(ala - hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_368496: ala - hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (48..447): ala
NRPSPredictor2: ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
gly, ala
Single AA prediction:
ala
Stachelhaus prediction details:
Stachelhaus sequence:
dasgllipyk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1142..1363): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dahnilapik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851906.1 - Region 7 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 751,649 - 800,043 nt. (total: 48,395 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 7, location 751648 - 800043:
Polymer prediction:
(redmmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_329685: redmmal
PKS_AT (511..815): redmmal
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 67.6
Methoxymalonyl-CoA: 61.2
Malonyl-CoA: 46.7
Isobutyryl-CoA: 35.4
Propionyl-CoA: 25.2
Ethylmalonyl-CoA: 21.9
2-Methylbutyryl-CoA: 12.9
3-Methylbutyryl-CoA: 10.2
CHC-CoA: 7.7
trans-1,2-CPDA: 6.3
Acetyl-CoA: 1.7
inactive: 0.0
fatty_acid: 0.0
Benzoyl-CoA: 0.0

ATSignature: Malonyl-CoA, Methylmalonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 75.0%
Ethylmalonyl-CoA: 66.7%


KZ851907.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 251,754 - 300,058 nt. (total: 48,305 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 251753 - 300058:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_364653: pk
PKS_AT (592..917): pk
minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 75.8
Methylmalonyl-CoA: 68.4
Malonyl-CoA: 59.6
Isobutyryl-CoA: 43.3
Propionyl-CoA: 36.5
Ethylmalonyl-CoA: 31.9
inactive: 21.9
fatty_acid: 21.5
Benzoyl-CoA: 19.7
3-Methylbutyryl-CoA: 18.4
CHC-CoA: 17.5
trans-1,2-CPDA: 15.4
2-Methylbutyryl-CoA: 14.4
Acetyl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
Methylmalonyl-CoA: 66.7%
2-Methylbutyryl-CoA: 58.3%


KZ851908.1 - Region 1 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 42,276 - 92,287 nt. (total: 50,012 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location <42275 - 92287:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(val - ala) + (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location <42275 - 88105:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(val - ala) + (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 51802 - 92287:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(val - ala) + (pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_294293: pk
PKS_AT (572..880): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 65.6
Methoxymalonyl-CoA: 61.7
Malonyl-CoA: 49.9
Propionyl-CoA: 33.6
Ethylmalonyl-CoA: 24.5
fatty_acid: 14.8
Isobutyryl-CoA: 12.5
CHC-CoA: 11.4
Benzoyl-CoA: 9.4
trans-1,2-CPDA: 8.3
2-Methylbutyryl-CoA: 6.4
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: -3.3

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 58.3%


M747DRAFT_368842: val - ala
Search NORINE for peptide: strict or relaxed

AMP-binding (204..598): val
NRPSPredictor2: val
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
val
Stachelhaus prediction details:
Stachelhaus sequence:
avcwtgsgwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1268..1665): ala
NRPSPredictor2: ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
ala
Stachelhaus prediction details:
Stachelhaus sequence:
daiwcmavlk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851908.1 - Region 2 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 132,745 - 190,064 nt. (total: 57,320 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 132744 - 190064:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - X - X - hydrophobic-aliphatic - leu)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_10612: X - X - X - hydrophobic-aliphatic - leu
Search NORINE for peptide: strict or relaxed

AMP-binding (273..673): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
tmyvaggalk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1382..1781): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dfiivgapik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2472..2869): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dlyiiglqck
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3562..3960): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
davviaamvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (4679..5074): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dailvgaqik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851908.1 - Region 3 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 718,132 - 765,679 nt. (total: 47,548 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 718131 - 765679:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_369040: pk
PKS_AT (587..904): pk
minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 71.8
Methylmalonyl-CoA: 67.7
Malonyl-CoA: 38.7
Propionyl-CoA: 37.9
Isobutyryl-CoA: 37.9
Ethylmalonyl-CoA: 37.6
inactive: 25.6
2-Methylbutyryl-CoA: 20.8
fatty_acid: 10.1
trans-1,2-CPDA: 8.8
Benzoyl-CoA: 5.3
Acetyl-CoA: 1.7
CHC-CoA: 0.0
3-Methylbutyryl-CoA: -2.9

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 58.3%
Isobutyryl-CoA: 58.3%


KZ851909.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1 - 41,060 nt. (total: 41,060 nt) Show pHMM detection rules used
Region on contig edge.
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 0 - 41060:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_322265: pk
PKS_AT (555..863): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 92.0
Methoxymalonyl-CoA: 89.2
Malonyl-CoA: 87.1
Isobutyryl-CoA: 75.0
Ethylmalonyl-CoA: 66.3
Benzoyl-CoA: 40.2
Propionyl-CoA: 35.2
2-Methylbutyryl-CoA: 30.9
trans-1,2-CPDA: 29.2
inactive: 28.8
Acetyl-CoA: 25.0
fatty_acid: 15.6
CHC-CoA: 13.5
3-Methylbutyryl-CoA: 10.6

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 87.5%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 62.5%


KZ851909.1 - Region 2 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 41,694 - 93,755 nt. (total: 52,062 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 41693 - 93755:
Polymer prediction:
(hydrophobic-aliphatic - hydrophobic-aliphatic - hydrophilic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_277425: hydrophobic-aliphatic - hydrophobic-aliphatic - hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (493..899): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dianmgnfvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1575..1976): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dawlvgavik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3116..3527): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dagsvggiek
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851909.1 - Region 3 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 672,915 - 709,092 nt. (total: 36,178 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 672914 - >709092:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_349043: X
Search NORINE for peptide: strict or relaxed

AMP-binding (20..423): X
NRPSPredictor2: phe, trp, phg, tyr, bht
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aromatic
Large clusters prediction:
phe, trp, phg, tyr, bht
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hmllygaiik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851909.1 - Region 4 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 829,729 - 851,128 nt. (total: 21,400 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851909.1 - Region 5 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 864,728 - 908,103 nt. (total: 43,376 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 864727 - 908103:
Polymer prediction:
(hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_322405: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (38..434): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hlvicgavik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851910.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 183,857 - 245,161 nt. (total: 61,305 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 183856 - 245161:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(leu - X - ala - hydrophobic-aliphatic - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_349340: leu - X - ala - hydrophobic-aliphatic - X
Search NORINE for peptide: strict or relaxed

AMP-binding (40..446): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dvsdvgpptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1698..2093): X
NRPSPredictor2: orn, lys, arg
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
orn, lys, arg
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvsdvgpptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3216..3620): ala
NRPSPredictor2: ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
gly, ala
Single AA prediction:
ala
Stachelhaus prediction details:
Stachelhaus sequence:
dvcihiltfk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (4305..4707): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvadtgsptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (5855..6252): X
NRPSPredictor2: orn, lys, arg
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
orn, lys, arg
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvsdvgpptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851911.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 13,293 - 34,788 nt. (total: 21,496 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851911.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 75,434 - 131,709 nt. (total: 56,276 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 75433 - 131709:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_349697: pk
PKS_AT (573..895): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 60.2
Methoxymalonyl-CoA: 55.1
Malonyl-CoA: 41.1
Isobutyryl-CoA: 21.5
Benzoyl-CoA: 13.9
fatty_acid: 12.4
inactive: 10.4
2-Methylbutyryl-CoA: 5.9
trans-1,2-CPDA: 0.0
Propionyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
Ethylmalonyl-CoA: -2.6

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 62.5%
Methylmalonyl-CoA: 58.3%
Ethylmalonyl-CoA: 54.2%


M747DRAFT_369591: pk
PKS_AT (575..896): pk
minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 72.3
Methylmalonyl-CoA: 68.9
Malonyl-CoA: 52.1
Isobutyryl-CoA: 48.5
Ethylmalonyl-CoA: 31.1
Propionyl-CoA: 22.2
3-Methylbutyryl-CoA: 15.1
2-Methylbutyryl-CoA: 12.1
fatty_acid: 11.7
trans-1,2-CPDA: 10.7
inactive: 10.7
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 66.7%
Methylmalonyl-CoA: 58.3%


KZ851911.1 - Region 3 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 178,269 - 240,789 nt. (total: 62,521 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 178268 - >240789:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 178268 - >221219:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 5, location <203103 - >240789:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_278434: pk
PKS_AT (540..844): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 66.2
Methoxymalonyl-CoA: 55.6
Propionyl-CoA: 51.2
2-Methylbutyryl-CoA: 26.7
CHC-CoA: 26.2
Benzoyl-CoA: 22.9
fatty_acid: 19.9
trans-1,2-CPDA: 17.2
Ethylmalonyl-CoA: 16.7
Malonyl-CoA: 10.1
Isobutyryl-CoA: 8.7
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Methylmalonyl-CoA: 58.3%
Propionyl-CoA: 58.3%


M747DRAFT_278447: X
Search NORINE for peptide: strict or relaxed

AMP-binding (87..350): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
nhsymgh--k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851911.1 - Region 4 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 491,515 - 544,621 nt. (total: 53,107 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 491514 - 544621:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 7, location 491514 - >534279:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 8, location 501295 - 544621:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_349913: pk
PKS_AT (546..860): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 91.3
Methoxymalonyl-CoA: 89.3
Ethylmalonyl-CoA: 65.8
Malonyl-CoA: 61.5
Isobutyryl-CoA: 60.9
Propionyl-CoA: 35.4
Benzoyl-CoA: 32.1
fatty_acid: 28.2
trans-1,2-CPDA: 26.0
Acetyl-CoA: 24.3
inactive: 21.5
CHC-CoA: 20.4
3-Methylbutyryl-CoA: 17.0
2-Methylbutyryl-CoA: 15.5

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 66.7%


KZ851911.1 - Region 5 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 575,993 - 624,800 nt. (total: 48,808 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 9, location 575992 - 624800:
Polymer prediction:
(redmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_349960: redmal
PKS_AT (595..931): redmal
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 90.6
Methylmalonyl-CoA: 79.7
Methoxymalonyl-CoA: 75.8
Isobutyryl-CoA: 55.5
Ethylmalonyl-CoA: 46.8
Propionyl-CoA: 40.5
inactive: 27.2
3-Methylbutyryl-CoA: 24.3
Benzoyl-CoA: 23.8
fatty_acid: 19.3
2-Methylbutyryl-CoA: 11.4
CHC-CoA: 11.2
trans-1,2-CPDA: 7.3
Acetyl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 70.8%
Ethylmalonyl-CoA: 62.5%


KZ851912.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 455,733 - 498,786 nt. (total: 43,054 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 455732 - 498786:
Polymer prediction:
(leu)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_369934: leu
Search NORINE for peptide: strict or relaxed

AMP-binding (6..406): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dlfflgttlk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851913.1 - Region 1 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 17,638 - 125,130 nt. (total: 107,493 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 17637 - >125130:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(hydrophobic-aliphatic - hydrophobic-aliphatic - X - X) + (phe) + (pk) + (redmmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 17637 - 94456:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(hydrophobic-aliphatic - hydrophobic-aliphatic - X - X) + (phe) + (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 57065 - >125130:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(phe) + (pk) + (redmmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_350427: hydrophobic-aliphatic - hydrophobic-aliphatic - X - X
Search NORINE for peptide: strict or relaxed

AMP-binding (224..616): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmlicgfink
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1326..1716): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
daamaigimk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2500..2894): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
damfgglivk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (4046..4443): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dawfvgailk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


M747DRAFT_258993: phe
Search NORINE for peptide: strict or relaxed

AMP-binding (20..432): phe
NRPSPredictor2: phe
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aromatic
Large clusters prediction:
N/A
Small clusters prediction:
phe, trp
Single AA prediction:
phe
Stachelhaus prediction details:
Stachelhaus sequence:
--lvislfck
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


M747DRAFT_370035: pk
PKS_AT (539..859): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 87.5
Methoxymalonyl-CoA: 77.3
Isobutyryl-CoA: 59.5
Ethylmalonyl-CoA: 52.9
Malonyl-CoA: 48.1
fatty_acid: 27.7
Propionyl-CoA: 27.2
Benzoyl-CoA: 23.3
inactive: 14.5
trans-1,2-CPDA: 14.4
2-Methylbutyryl-CoA: 11.6
3-Methylbutyryl-CoA: 8.7
CHC-CoA: 8.3
Acetyl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 66.7%


M747DRAFT_314772: redmmal
PKS_AT (548..850): redmmal
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 84.3
Methoxymalonyl-CoA: 69.6
Malonyl-CoA: 68.9
Isobutyryl-CoA: 60.6
Ethylmalonyl-CoA: 52.8
Benzoyl-CoA: 43.7
Propionyl-CoA: 38.4
fatty_acid: 21.1
trans-1,2-CPDA: 20.6
2-Methylbutyryl-CoA: 18.9
Acetyl-CoA: 15.2
CHC-CoA: 11.8
inactive: 10.6
3-Methylbutyryl-CoA: 0.0

ATSignature: Methylmalonyl-CoA, Malonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 75.0%
Malonyl-CoA: 75.0%
Isobutyryl-CoA: 62.5%


KZ851913.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 212,899 - 260,664 nt. (total: 47,766 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 212898 - 260664:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (mal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_279397: mal
PKS_AT (990..1174): mal
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 21.1
Methoxymalonyl-CoA: 21.0
inactive: 10.8
Methylmalonyl-CoA: 10.1
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: (unknown)
No matches above 50%


M747DRAFT_279403: pk
PKS_AT (1683..1876): pk
minowa: trans-1,2-CPDA
Prediction, score:
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: (unknown)
No matches above 50%


KZ851913.1 - Region 3 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 276,280 - 297,885 nt. (total: 21,606 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851914.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 537,361 - 558,320 nt. (total: 20,960 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851915.1 - Region 1 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 103,506 - 115,649 nt. (total: 12,144 nt) Show pHMM detection rules used
siderophore: IucA_IucC

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851915.1 - Region 2 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 126,316 - 164,190 nt. (total: 37,875 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location <126315 - >164190:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_259919: X
Search NORINE for peptide: strict or relaxed

AMP-binding (268..736): X
NRPSPredictor2: asp, asn, glu, gln, aad
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dprhfvmrak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851915.1 - Region 3 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 355,060 - 412,549 nt. (total: 57,490 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 355059 - 412549:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 355059 - 398719:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 5, location 365105 - 412549:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk) + (X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_331574: X
Search NORINE for peptide: strict or relaxed

AMP-binding (82..487): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmcivggifk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


M747DRAFT_295861: pk
PKS_AT (547..861): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 64.3
Methoxymalonyl-CoA: 58.3
Ethylmalonyl-CoA: 47.4
Isobutyryl-CoA: 37.7
Malonyl-CoA: 35.0
trans-1,2-CPDA: 25.0
Benzoyl-CoA: 24.6
fatty_acid: 16.8
CHC-CoA: 14.2
2-Methylbutyryl-CoA: 13.1
Propionyl-CoA: 8.7
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Methylmalonyl-CoA: 62.5%
Ethylmalonyl-CoA: 58.3%


M747DRAFT_237486: X
Search NORINE for peptide: strict or relaxed

AMP-binding (83..492): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
fswygavvfk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851916.1 - Region 1 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 239,058 - 291,157 nt. (total: 52,100 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 239057 - 291157:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_260454: pk - X
Search NORINE for peptide: strict or relaxed

PKS_AT (486..801): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 76.0
Methoxymalonyl-CoA: 65.6
Malonyl-CoA: 48.1
Isobutyryl-CoA: 41.7
Benzoyl-CoA: 34.9
Ethylmalonyl-CoA: 34.5
Propionyl-CoA: 27.1
3-Methylbutyryl-CoA: 19.7
fatty_acid: 15.8
Acetyl-CoA: 15.4
inactive: 15.0
trans-1,2-CPDA: 11.8
CHC-CoA: 9.0
2-Methylbutyryl-CoA: 7.2

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 66.7%
2-Methylbutyryl-CoA: 58.3%

AMP-binding (2849..3234): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
daftfvamak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851917.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 263,450 - 310,701 nt. (total: 47,252 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 263449 - 310701:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_260901: pk
PKS_AT (537..848): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 54.1
Methoxymalonyl-CoA: 53.7
Isobutyryl-CoA: 45.4
Malonyl-CoA: 39.4
inactive: 29.9
Propionyl-CoA: 25.3
Ethylmalonyl-CoA: 19.9
trans-1,2-CPDA: 16.2
Acetyl-CoA: 13.9
fatty_acid: 12.2
CHC-CoA: 12.2
Benzoyl-CoA: 10.5
2-Methylbutyryl-CoA: 7.2
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 66.7%
Isobutyryl-CoA: 62.5%
Methylmalonyl-CoA: 62.5%


KZ851917.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 314,276 - 336,834 nt. (total: 22,559 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851918.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 250,873 - 297,337 nt. (total: 46,465 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 250872 - 297337:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_353001: pk
PKS_AT (884..1173): pk
minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 54.9
Malonyl-CoA: 51.1
Methylmalonyl-CoA: 48.9
inactive: 43.0
Ethylmalonyl-CoA: 36.3
Propionyl-CoA: 27.4
CHC-CoA: 27.2
Acetyl-CoA: 25.9
fatty_acid: 23.0
2-Methylbutyryl-CoA: 20.6
trans-1,2-CPDA: 20.3
Benzoyl-CoA: 16.3
Isobutyryl-CoA: 16.2
3-Methylbutyryl-CoA: 11.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 62.5%
Ethylmalonyl-CoA: 54.2%
inactive: 54.2%


KZ851918.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 451,835 - 473,508 nt. (total: 21,674 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851918.1 - Region 3 - NRPS,terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 477,513 - 524,578 nt. (total: 47,066 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 477512 - 524578:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(leu - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 477512 - 524319:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(leu - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_281712: leu - X
Search NORINE for peptide: strict or relaxed

AMP-binding (34..370): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dalfig---k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1070..1472): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
digsvamiyk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851919.1 - Region 1 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 59,844 - 101,070 nt. (total: 41,227 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851919.1 - Region 2 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 264,390 - 323,409 nt. (total: 59,020 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 264389 - 323409:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - pro - X) + (X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_261582: X - pro - X
Search NORINE for peptide: strict or relaxed

AMP-binding (270..715): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dpamwitiak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1428..1837): pro
NRPSPredictor2: pro
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
pro
Stachelhaus prediction details:
Stachelhaus sequence:
dvqhtitvvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2553..2958): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dplstgaigk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


M747DRAFT_281896: X
Search NORINE for peptide: strict or relaxed

AMP-binding (48..471): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
gllhiasptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851920.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 70,069 - 89,171 nt. (total: 19,103 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851920.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 242,445 - 267,434 nt. (total: 24,990 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851920.1 - Region 3 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 354,757 - 398,137 nt. (total: 43,381 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 354756 - 398137:
Polymer prediction:
(hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_371431: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (23..349): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
aayldcc--k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851921.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 236,475 - 257,431 nt. (total: 20,957 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851921.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 328,031 - 369,580 nt. (total: 41,550 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 328030 - >369580:
Polymer prediction:
(mmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_353924: mmal
PKS_AT (979..1302): mmal
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 36.0
Methoxymalonyl-CoA: 35.0
Propionyl-CoA: 18.8
Ethylmalonyl-CoA: 15.1
inactive: 14.5
trans-1,2-CPDA: 13.0
2-Methylbutyryl-CoA: 12.4
3-Methylbutyryl-CoA: 11.9
fatty_acid: 11.2
CHC-CoA: 10.9
Malonyl-CoA: 7.5
Isobutyryl-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0

ATSignature: Methylmalonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 58.3%
Methoxymalonyl-CoA: 54.2%
Isobutyryl-CoA: 54.2%


KZ851921.1 - Region 3 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 369,980 - 476,091 nt. (total: 106,112 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 369979 - 476091:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - hydrophobic-aliphatic) + (pk) + (hydrophobic-aliphatic) + (pk) + (redmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 4, location 369979 - >430975:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(hydrophobic-aliphatic) + (pk) + (redmal)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 5, location 426851 - 476091:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (X - hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_353971: redmal
PKS_AT (579..901): redmal
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 86.5
Methylmalonyl-CoA: 65.6
Methoxymalonyl-CoA: 64.8
Isobutyryl-CoA: 29.4
Benzoyl-CoA: 21.9
inactive: 21.7
CHC-CoA: 16.7
fatty_acid: 16.3
trans-1,2-CPDA: 16.2
Propionyl-CoA: 14.9
2-Methylbutyryl-CoA: 13.0
Ethylmalonyl-CoA: 5.9
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 66.7%
Methylmalonyl-CoA: 62.5%
Isobutyryl-CoA: 54.2%


M747DRAFT_353979: pk
PKS_AT (900..1196): pk
minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 67.6
Methylmalonyl-CoA: 56.5
Malonyl-CoA: 52.8
inactive: 44.7
Ethylmalonyl-CoA: 26.0
trans-1,2-CPDA: 24.6
Propionyl-CoA: 22.5
CHC-CoA: 21.7
Isobutyryl-CoA: 18.0
2-Methylbutyryl-CoA: 16.5
Benzoyl-CoA: 14.2
3-Methylbutyryl-CoA: 13.6
Acetyl-CoA: 11.0
fatty_acid: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Ethylmalonyl-CoA: 54.2%
inactive: 54.2%


M747DRAFT_332601: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (21..441): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
aasargvcik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


M747DRAFT_371602: pk
PKS_AT (1687..1938): pk
minowa: trans-1,2-CPDA
Prediction, score:
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: (unknown)
No matches above 50%


M747DRAFT_324080: X - hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (240..591): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
---fvggvak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1703..2098): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvlfvggvak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851921.1 - Region 4 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 511,251 - 559,576 nt. (total: 48,326 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 511250 - 559576:
Polymer prediction:
(redmmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_354091: redmmal
PKS_AT (491..796): redmmal
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 78.7
Methoxymalonyl-CoA: 68.2
Malonyl-CoA: 59.4
Isobutyryl-CoA: 47.6
Ethylmalonyl-CoA: 46.5
Propionyl-CoA: 39.5
Benzoyl-CoA: 28.2
trans-1,2-CPDA: 27.6
fatty_acid: 21.5
2-Methylbutyryl-CoA: 17.7
Acetyl-CoA: 14.8
CHC-CoA: 12.3
3-Methylbutyryl-CoA: 10.1
inactive: 0.0

ATSignature: Methylmalonyl-CoA, Malonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 70.8%
Malonyl-CoA: 70.8%
Ethylmalonyl-CoA: 62.5%


KZ851922.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 20,094 - 63,887 nt. (total: 43,794 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 20093 - 63887:
Polymer prediction:
(hydrophilic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_354131: hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (62..359): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hasymgh--k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851922.1 - Region 2 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 450,679 - 479,789 nt. (total: 29,111 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851923.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 171,250 - 224,487 nt. (total: 53,238 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 171249 - 224487:
Polymer prediction:
(hydrophobic-aromatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_283013: hydrophobic-aromatic
Search NORINE for peptide: strict or relaxed

AMP-binding (113..555): hydrophobic-aromatic
NRPSPredictor2: hydrophobic-aromatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aromatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
imvgttigck
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851924.1 - Region 1 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 7,093 - 59,236 nt. (total: 52,144 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 7092 - 59236:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk - gln)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_354631: pk - gln
Search NORINE for peptide: strict or relaxed

PKS_AT (550..868): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 76.3
Methoxymalonyl-CoA: 61.9
Ethylmalonyl-CoA: 55.9
Malonyl-CoA: 37.3
Isobutyryl-CoA: 34.7
Benzoyl-CoA: 28.7
Propionyl-CoA: 23.5
fatty_acid: 22.5
trans-1,2-CPDA: 20.4
Acetyl-CoA: 14.5
CHC-CoA: 12.1
3-Methylbutyryl-CoA: 10.1
inactive: 0.0
2-Methylbutyryl-CoA: -1.3

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 58.3%

AMP-binding (2993..3402): gln
NRPSPredictor2: gln
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
glu, gln
Single AA prediction:
gln
Stachelhaus prediction details:
Stachelhaus sequence:
nhdkfgsisk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851924.1 - Region 2 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 384,320 - 443,640 nt. (total: 59,321 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 384319 - 443640:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - X - hydrophilic - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_372031: X - X - hydrophilic - X
Search NORINE for peptide: strict or relaxed

AMP-binding (254..652): X
NRPSPredictor2: phe, trp, phg, tyr, bht
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aromatic
Large clusters prediction:
phe, trp, phg, tyr, bht
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
daviiaavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1797..2197): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmqsvafssk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2839..3243): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvlstgavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3930..4331): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
damfvggifk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851925.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 424,793 - 458,956 nt. (total: 34,164 nt) Show pHMM detection rules used
Region on contig edge.
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 424792 - 458956:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_297411: X
Search NORINE for peptide: strict or relaxed

AMP-binding (25..424): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dtvqiggvyk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851930.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 61,190 - 108,681 nt. (total: 47,492 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 61189 - 108681:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_372701: pk
PKS_AT (552..862): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 88.2
Ethylmalonyl-CoA: 81.9
Methoxymalonyl-CoA: 78.9
Malonyl-CoA: 59.1
Isobutyryl-CoA: 56.0
Propionyl-CoA: 30.5
Benzoyl-CoA: 28.2
2-Methylbutyryl-CoA: 20.4
fatty_acid: 17.3
CHC-CoA: 17.2
trans-1,2-CPDA: 16.4
inactive: 12.3
3-Methylbutyryl-CoA: 9.6
Acetyl-CoA: 2.3

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Methylmalonyl-CoA: 58.3%
Ethylmalonyl-CoA: 54.2%


M747DRAFT_99023: X
Search NORINE for peptide: strict or relaxed

AMP-binding (30..432): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
gawfgsspvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851932.1 - Region 1 - bacteriocin
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 10,799 - 21,489 nt. (total: 10,691 nt) Show pHMM detection rules used
bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851935.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 80,441 - 125,571 nt. (total: 45,131 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location <80440 - 125571:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(val) + (hydrophilic)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location <80440 - 119319:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(val) + (hydrophilic)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 82567 - 125571:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(val) + (hydrophilic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_357382: val
Search NORINE for peptide: strict or relaxed

AMP-binding (239..634): val
NRPSPredictor2: val
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
val
Stachelhaus prediction details:
Stachelhaus sequence:
dlvftgsmfk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


M747DRAFT_244289: hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (59..465): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
vaefnggagk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851936.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 280,432 - 322,929 nt. (total: 42,498 nt) Show pHMM detection rules used
Region on contig edge.
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 280431 - 322929:
Polymer prediction:
(mmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_244500: mmal
PKS_AT (548..848): mmal
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 78.3
Methoxymalonyl-CoA: 71.8
Isobutyryl-CoA: 67.3
Malonyl-CoA: 47.0
Ethylmalonyl-CoA: 43.1
Propionyl-CoA: 36.4
2-Methylbutyryl-CoA: 31.0
Benzoyl-CoA: 27.2
trans-1,2-CPDA: 22.6
3-Methylbutyryl-CoA: 20.7
CHC-CoA: 18.0
fatty_acid: 15.6
inactive: 10.4
Acetyl-CoA: 0.0

ATSignature: Malonyl-CoA, Isobutyryl-CoA, Methylmalonyl-CoA
Top 3 matches:
Malonyl-CoA: 62.5%
Isobutyryl-CoA: 62.5%
Methylmalonyl-CoA: 62.5%


KZ851937.1 - Region 1 - indole
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 25,349 - 46,708 nt. (total: 21,360 nt) Show pHMM detection rules used
indole: (indsynth or dmat or indole_PTase)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851938.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 149,212 - 205,704 nt. (total: 56,493 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 149211 - 205704:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - pro - X - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_358539: X - pro - X - X
Search NORINE for peptide: strict or relaxed

AMP-binding (225..634): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvlfaggvak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1730..2128): pro
NRPSPredictor2: pro
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
pro, pip
Small clusters prediction:
pro
Single AA prediction:
pro
Stachelhaus prediction details:
Stachelhaus sequence:
dtqhfasvak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2823..3220): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvsfagsiwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3903..4299): X
NRPSPredictor2: gly, ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
gly, ala
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
digsvgiiyk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851938.1 - Region 2 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 270,855 - 282,954 nt. (total: 12,100 nt) Show pHMM detection rules used
siderophore: IucA_IucC

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851939.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 268,886 - 302,354 nt. (total: 33,469 nt) Show pHMM detection rules used
Region on contig edge.
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 268885 - 302354:
Polymer prediction:
(mal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_286938: mal
PKS_AT (925..1226): mal
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 97.5
Methylmalonyl-CoA: 68.4
inactive: 64.8
Methoxymalonyl-CoA: 53.8
Isobutyryl-CoA: 37.4
Ethylmalonyl-CoA: 32.6
Acetyl-CoA: 31.1
Propionyl-CoA: 29.5
Benzoyl-CoA: 24.6
2-Methylbutyryl-CoA: 21.1
fatty_acid: 20.9
3-Methylbutyryl-CoA: 19.5
CHC-CoA: 14.1
trans-1,2-CPDA: 13.1

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
inactive: 70.8%


KZ851941.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 204,656 - 226,979 nt. (total: 22,324 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851942.1 - Region 1 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 91,357 - 174,926 nt. (total: 83,570 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 91356 - 174926:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 91356 - 143277:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 115861 - 174926:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_287371: X
Search NORINE for peptide: strict or relaxed

AMP-binding (24..432): X
NRPSPredictor2: asp, asn, glu, gln, aad
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
iighrgvpak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


M747DRAFT_373775: pk
PKS_AT (582..886): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 86.6
Methoxymalonyl-CoA: 72.2
Ethylmalonyl-CoA: 46.8
Isobutyryl-CoA: 42.7
Propionyl-CoA: 42.3
Malonyl-CoA: 30.6
Benzoyl-CoA: 30.2
fatty_acid: 27.3
trans-1,2-CPDA: 26.4
2-Methylbutyryl-CoA: 15.9
CHC-CoA: 15.7
Acetyl-CoA: 0.9
inactive: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Propionyl-CoA: 62.5%
2-Methylbutyryl-CoA: 62.5%


M747DRAFT_359358: pk
PKS_AT (544..856): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 69.0
Methoxymalonyl-CoA: 54.0
Malonyl-CoA: 47.7
3-Methylbutyryl-CoA: 31.6
Ethylmalonyl-CoA: 31.3
Propionyl-CoA: 26.1
Benzoyl-CoA: 21.4
Acetyl-CoA: 21.4
CHC-CoA: 21.3
fatty_acid: 18.6
2-Methylbutyryl-CoA: 18.3
Isobutyryl-CoA: 17.4
trans-1,2-CPDA: 15.2
inactive: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
CE-Malonyl-CoA: 62.5%
Methylmalonyl-CoA: 62.5%


KZ851944.1 - Region 1 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 176,038 - 227,889 nt. (total: 51,852 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 176037 - 227889:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk - hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_334844: pk - hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

PKS_AT (541..854): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 88.5
Methoxymalonyl-CoA: 85.2
Isobutyryl-CoA: 79.1
Malonyl-CoA: 68.2
Ethylmalonyl-CoA: 47.5
Propionyl-CoA: 45.7
Benzoyl-CoA: 39.1
inactive: 38.5
3-Methylbutyryl-CoA: 30.4
trans-1,2-CPDA: 26.0
2-Methylbutyryl-CoA: 24.2
Acetyl-CoA: 23.4
CHC-CoA: 11.7
fatty_acid: 10.7

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 62.5%
Isobutyryl-CoA: 54.2%

AMP-binding (2831..3244): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dlvylatvqk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851944.1 - Region 2 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 240,656 - 288,965 nt. (total: 48,310 nt) Show pHMM detection rules used
Region on contig edge.
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 240655 - 288965:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(hydrophobic-aliphatic - X - pro)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_359698: hydrophobic-aliphatic - X - pro
Search NORINE for peptide: strict or relaxed

AMP-binding (238..633): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
vmaivavgak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1395..1801): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmwmfaavlk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2480..2831): pro
NRPSPredictor2: pro
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
pro, pip
Small clusters prediction:
pro
Single AA prediction:
pro
Stachelhaus prediction details:
Stachelhaus sequence:
dawf---vlk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851945.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 50,987 - 72,286 nt. (total: 21,300 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851945.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 120,958 - 164,462 nt. (total: 43,505 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 120957 - 164462:
Polymer prediction:
(mal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_374043: mal
PKS_AT (912..1211): mal
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 110.5
inactive: 48.6
Methoxymalonyl-CoA: 48.3
Methylmalonyl-CoA: 44.4
Propionyl-CoA: 19.9
Benzoyl-CoA: 17.2
2-Methylbutyryl-CoA: 15.8
Ethylmalonyl-CoA: 13.2
Isobutyryl-CoA: 12.5
CHC-CoA: 11.2
fatty_acid: 10.4
trans-1,2-CPDA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 100.0%
Methylmalonyl-CoA: 62.5%
Isobutyryl-CoA: 58.3%


KZ851945.1 - Region 3 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 215,615 - 263,797 nt. (total: 48,183 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 215614 - 263797:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_359789: pk
PKS_AT (545..848): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 64.8
Methoxymalonyl-CoA: 61.8
Malonyl-CoA: 55.6
Isobutyryl-CoA: 33.4
Propionyl-CoA: 31.0
CHC-CoA: 25.5
fatty_acid: 22.6
2-Methylbutyryl-CoA: 22.1
Benzoyl-CoA: 17.8
inactive: 13.4
trans-1,2-CPDA: 9.9
3-Methylbutyryl-CoA: 7.2
Acetyl-CoA: 0.0
Ethylmalonyl-CoA: -2.4

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 62.5%


KZ851949.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 80,958 - 127,753 nt. (total: 46,796 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location <80957 - 127753:
Polymer prediction:
(redmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_335162: redmal
PKS_AT (577..922): redmal
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 92.1
Methoxymalonyl-CoA: 78.8
Methylmalonyl-CoA: 78.2
Isobutyryl-CoA: 56.8
Ethylmalonyl-CoA: 49.9
inactive: 41.9
Propionyl-CoA: 39.1
Benzoyl-CoA: 29.8
2-Methylbutyryl-CoA: 20.4
Acetyl-CoA: 16.4
fatty_acid: 16.3
trans-1,2-CPDA: 15.9
3-Methylbutyryl-CoA: 10.3
CHC-CoA: 7.7

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 62.5%
inactive: 54.2%


KZ851949.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 198,066 - 236,394 nt. (total: 38,329 nt) Show pHMM detection rules used
Region on contig edge.
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 198065 - 236394:
Polymer prediction:
(mal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_360775: mal
PKS_AT (830..1129): mal
minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 71.5
inactive: 51.9
Methoxymalonyl-CoA: 45.1
Methylmalonyl-CoA: 40.2
2-Methylbutyryl-CoA: 19.3
Propionyl-CoA: 18.2
Isobutyryl-CoA: 14.2
Ethylmalonyl-CoA: 13.9
fatty_acid: 12.7
CHC-CoA: 12.4
trans-1,2-CPDA: 11.9
3-Methylbutyryl-CoA: 10.6
Benzoyl-CoA: 9.8
Acetyl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%


KZ851952.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 11,342 - 56,681 nt. (total: 45,340 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 11341 - 56681:
Polymer prediction:
(ccmmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_299640: ccmmal
PKS_AT (586..877): ccmmal
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 111.9
Ethylmalonyl-CoA: 94.8
Methoxymalonyl-CoA: 91.0
Isobutyryl-CoA: 67.1
Malonyl-CoA: 58.2
trans-1,2-CPDA: 46.4
Benzoyl-CoA: 44.0
Propionyl-CoA: 40.9
2-Methylbutyryl-CoA: 40.5
Acetyl-CoA: 31.8
fatty_acid: 30.0
CHC-CoA: 16.5
3-Methylbutyryl-CoA: 16.1
inactive: 10.4

ATSignature: Methylmalonyl-CoA, Malonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 75.0%
Malonyl-CoA: 75.0%
Ethylmalonyl-CoA: 70.8%


KZ851953.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 19,470 - 41,486 nt. (total: 22,017 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851953.1 - Region 2 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 146,050 - 193,119 nt. (total: 47,070 nt) Show pHMM detection rules used
Region on contig edge.
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 146049 - 193119:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk - leu)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_326354: X
Search NORINE for peptide: strict or relaxed

AMP-binding (29..483): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
gllyigcpik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


M747DRAFT_361212: pk - leu
Search NORINE for peptide: strict or relaxed

PKS_AT (568..884): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 66.7
Methoxymalonyl-CoA: 59.4
Ethylmalonyl-CoA: 38.6
Propionyl-CoA: 31.7
Isobutyryl-CoA: 23.0
Benzoyl-CoA: 20.1
3-Methylbutyryl-CoA: 14.0
2-Methylbutyryl-CoA: 13.6
fatty_acid: 13.3
inactive: 11.2
Malonyl-CoA: 10.7
trans-1,2-CPDA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
Methylmalonyl-CoA: 66.7%
2-Methylbutyryl-CoA: 58.3%

AMP-binding (2822..3231): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
daalmgavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851954.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 28,348 - 50,664 nt. (total: 22,317 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851955.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 115,055 - 163,229 nt. (total: 48,175 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 115054 - 163229:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_374673: pk
PKS_AT (631..951): pk
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 66.3
Malonyl-CoA: 63.1
Methoxymalonyl-CoA: 54.1
Ethylmalonyl-CoA: 38.7
Isobutyryl-CoA: 28.5
2-Methylbutyryl-CoA: 18.7
Propionyl-CoA: 18.2
trans-1,2-CPDA: 17.4
inactive: 17.3
Benzoyl-CoA: 15.2
CHC-CoA: 15.1
fatty_acid: 7.5
Acetyl-CoA: 1.4
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 62.5%
Ethylmalonyl-CoA: 58.3%


KZ851956.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 35,458 - 95,413 nt. (total: 59,956 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 35457 - 95413:
Polymer prediction:
(hydrophobic-aromatic) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_326459: hydrophobic-aromatic
Search NORINE for peptide: strict or relaxed

AMP-binding (532..913): hydrophobic-aromatic
NRPSPredictor2: hydrophobic-aromatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aromatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dghiyvmcgk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


M747DRAFT_289585: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (22..343): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
----liaglk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851957.1 - Region 1 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 1 - 45,372 nt. (total: 45,372 nt) Show pHMM detection rules used
Region on contig edge.
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 0 - 45372:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(ccmmal - leu)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_361485: ccmmal - leu
Search NORINE for peptide: strict or relaxed

PKS_AT (551..848): ccmmal
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 48.0
Methoxymalonyl-CoA: 38.2
Ethylmalonyl-CoA: 23.4
Benzoyl-CoA: 22.4
Propionyl-CoA: 22.3
Isobutyryl-CoA: 16.5
fatty_acid: 11.0
inactive: 8.4
trans-1,2-CPDA: 7.8
Malonyl-CoA: 3.1
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA, Methylmalonyl-CoA
Top 3 matches:
Malonyl-CoA: 62.5%
Methylmalonyl-CoA: 62.5%
Ethylmalonyl-CoA: 54.2%

AMP-binding (2901..3303): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dafllgavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851958.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 80,883 - 102,004 nt. (total: 21,122 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851964.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 55,726 - 78,286 nt. (total: 22,561 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

KZ851965.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 57,254 - 104,797 nt. (total: 47,544 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 57253 - 104797:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_362721: X - X
Search NORINE for peptide: strict or relaxed

AMP-binding (257..636): X
NRPSPredictor2: asp, asn, glu, gln, aad
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
sardvgsqlk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1280..1664): X
NRPSPredictor2: phe, trp
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
phe, trp
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dgfcagaick
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851966.1 - Region 1 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 25,961 - 77,700 nt. (total: 51,740 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 25960 - 77700:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(redmal - X)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_270180: redmal - X
Search NORINE for peptide: strict or relaxed

PKS_AT (499..815): redmal
minowa: Isobutyryl-CoA
Prediction, score:
Isobutyryl-CoA: 77.4
Methylmalonyl-CoA: 76.9
Methoxymalonyl-CoA: 69.4
Malonyl-CoA: 62.0
Ethylmalonyl-CoA: 41.3
Propionyl-CoA: 33.7
inactive: 30.4
3-Methylbutyryl-CoA: 29.7
2-Methylbutyryl-CoA: 27.8
Benzoyl-CoA: 24.2
trans-1,2-CPDA: 21.6
Acetyl-CoA: 13.8
CHC-CoA: 12.1
fatty_acid: 11.4

ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 62.5%
inactive: 58.3%

AMP-binding (2791..3200): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dlgylccvqk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


KZ851967.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 41,937 - 89,759 nt. (total: 47,823 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 41936 - 89759:
Polymer prediction:
(redmmal)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_362857: redmmal
PKS_AT (554..856): redmmal
minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 71.0
Methoxymalonyl-CoA: 67.0
Malonyl-CoA: 36.4
Propionyl-CoA: 34.7
Ethylmalonyl-CoA: 31.5
trans-1,2-CPDA: 31.1
fatty_acid: 25.3
2-Methylbutyryl-CoA: 21.4
CHC-CoA: 16.9
Isobutyryl-CoA: 15.8
Benzoyl-CoA: 15.6
Acetyl-CoA: 8.4
inactive: 0.0
3-Methylbutyryl-CoA: 0.0

ATSignature: Malonyl-CoA, Methylmalonyl-CoA
Top 3 matches:
Malonyl-CoA: 66.7%
Methylmalonyl-CoA: 66.7%
CE-Malonyl-CoA: 62.5%


KZ851973.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Location: 3,760 - 46,861 nt. (total: 43,102 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 3759 - 46861:
Polymer prediction:
(hydrophilic)

Direct lookup in NORINE database: strict or relaxed
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
M747DRAFT_311054: hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (49..422): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
vamflgsagk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)