LOCUS       KZ851905.1             21310 bp    DNA     linear   PLN 20-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   KZ851905
VERSION     KZ851905.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 07:38:58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 326806
            Orig. end    :: 348116
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21310
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[<336806:336877](+),
                     [336937:338012](+), [338062:338116](+)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(<10001..10071,10132..11206,11257..11310)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..21310
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21310
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            join(<2979..3074,3139..3604,3652..3744,3793..>4331)
                     /locus_tag="M747DRAFT_368108"
                     /product="hypothetical protein"
     gene            <2979..>4331
                     /locus_tag="M747DRAFT_368108"
     CDS             join(<2979..3074,3139..3604,3652..3744,3793..>4331)
                     /codon_start=1
                     /locus_tag="M747DRAFT_368108"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_368108-T1"
                     /transl_table=1
                     /translation="MDSAALNITSSQASQTPPAIGDIGRITQRQYGIAVGVFFALASLS
                     FFGRIFIRLFTRRRLYLDDAFLSFAFTTLLIGTVLGFLRAYTIYFQMAALEGNVGAVLF
                     LASHLNEHAKDYGFNIAFIVLLWTTVFAVKWCYLAFFQPLLVGMSRWFIIYYRFTVGLS
                     VISWILSAFVAPIVPCPYTGMKAISKCFPTLPVPNSTVLAMIWLPPILDAVTDLMIISI
                     PIRLLYKVQLRTLTKLGLGCFLCLSIFMCTCSIIRTAGTWYHGLLDYPWQVFWLHLEGC
                     IGVTMGSITVYRSTLIGSSEVSTAFKRYFTRIKDAVLGSSSGTAQAPPTEENKTRTRQF
                     GLPSIPQATITGLRTWFGFSRRDPAASNDASGITSFNSDIDYHTLLKAPKAAASHPQ"
     mRNA            join(4807..5720,5781..6058)
                     /locus_tag="M747DRAFT_275448"
                     /product="short-chain dehydrogenase/reductase family
                     protein"
     gene            4807..6058
                     /locus_tag="M747DRAFT_275448"
     CDS             join(4813..5720,5781..5895)
                     /codon_start=1
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF00106"
                     /db_xref="PFAM:PF08659"
                     /db_xref="PFAM:PF13561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     100.8; E-value: 1.5e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_275448"
                     /note="EggNog:ENOG41"
                     /product="short-chain dehydrogenase/reductase family
                     protein"
                     /protein_id="ncbi_M747DRAFT_275448-T1"
                     /transl_table=1
                     /translation="MASKDLPPSTAPFFPNVFFYNQFCAKPNWPPATTNLSGQVAIITG
                     GNTGLGFECAFQLLSLQLSHLILAVRSLEKGEAAAAKLRAVNPTSTIDVWPLDMSSYDS
                     IQSFAKRVENHLSRLDIAILNAGVRQAQFTTNPSTGHEETIQVNYLSTMLLAILLLPSL
                     RDKSPKGVPGRLTIVSAALSLLPSLPNVKDAPLLKLFDRPDTYDANGIYCMSKLLAHAF
                     LYKLVEYVGADDVIVNLADPAFVKGTDLSRDSPGLAKAGLAVFGVLTGRTVKVGASTFI
                     DAAVLKGKESHGCFLMSWKIEPFNASLYTPEGKQSIEQLWQETMDELDFAGVRRILETL
                     "
     mRNA            6332..7589
                     /locus_tag="M747DRAFT_293584"
                     /product="hypothetical protein"
     gene            6332..7589
                     /locus_tag="M747DRAFT_293584"
     CDS             6630..7478
                     /codon_start=1
                     /db_xref="InterPro:IPR004045"
                     /db_xref="InterPro:IPR010987"
                     /db_xref="InterPro:IPR036249"
                     /db_xref="InterPro:IPR036282"
                     /db_xref="PFAM:PF13409"
                     /db_xref="PFAM:PF13410"
                     /db_xref="PFAM:PF13417"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_N_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_293584"
                     /note="EggNog:ENOG41; GO_function: GO:0005515 - protein
                     binding [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_293584-T1"
                     /sec_met_domain="GST_N_3 (E-value: 5.4e-07, bitscore: 24.5,
                     seeds: 52, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MATTTTTSNPTPTMTYYDIAMRPPVTRNAAAVNPWKARLALNFKN
                     APYSTTWVKLPEVSKVRRSLNLPACRKFADGSDFYTLPILSDPTTNSLIGDSFDIAVYL
                     QKTYPASGGGDLFPPQNLDYELKEELKVLVPLSERNDIEYADYARFNNNVDAAFSVHTM
                     LMVQKMPFDPETAEESKAEFVRRAGLKSWDDFTLEGEKREQVLASFREMLKDLARMFER
                     DPSGPFLLGERPSHADFIVGGWLRMSRVTLPSTEWEQLREWHGGVFGRLHDALDVYAEV
                     K"
     mRNA            complement(join(<7595..8073,8306..8609,8977..>9558))
                     /locus_tag="M747DRAFT_275453"
                     /product="hypothetical protein"
     gene            complement(<7595..>9558)
                     /locus_tag="M747DRAFT_275453"
     CDS             complement(join(<7595..8073,8306..8609,8977..>9558))
                     /codon_start=1
                     /locus_tag="M747DRAFT_275453"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_275453-T1"
                     /transl_table=1
                     /translation="MVRCFRLKVECRPSPTVRRRGSKPNGSQAARLEQKLDGLVSLLKA
                     RQGSPEIGDTASSSASLTSALSHASVPADRGSHAQPLVGDLDRVATDHGKSRHCSSPRS
                     PPSSDSSCLFPYSLPAGVEPTSRNAKQRLRTFCNHYTKFLPLIYLENGLTSEKLYRESP
                     FLWLCIMAVTSTNAREQSNLGKAVREVAARENAANSTISIAAFQTVGENLAWSPYMEEC
                     LKMIQGLRNLPGDDLLVQMIKLQRITSKVTDLRIQLRDADCEQSTRLISPYMSALSTQL
                     AETRKSFPPHLATDNYIYFPFFLWRQFRTVILTLIRLASLEDPAWDVNMVRRTVDITSI
                     LDRTAENLSNVQPTSDEGDDHENVVAKSLAWVNRMRTCLLAVYGQSTDAQTPTSGGNGS
                     MGIPGVKTLLSGQAAWDVSLLNGGLGMDIFSSFEEDIFGEDISGWWPQLYSENGL"
     CDS             join(<10001..10071,10132..11206,11257..11310)
                     /codon_start=1
                     /db_xref="InterPro:IPR002060"
                     /db_xref="InterPro:IPR006449"
                     /db_xref="InterPro:IPR008949"
                     /db_xref="InterPro:IPR019845"
                     /db_xref="InterPro:IPR033904"
                     /db_xref="PFAM:PF00494"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="M747DRAFT_363127"
                     /note="GO_component: GO:0016021 - integral component of
                     membrane [Evidence IEA]; GO_function: GO:0016740 -
                     transferase activity [Evidence IEA]; GO_function:
                     GO:0016765 - transferase activity, transferring alkyl or
                     aryl (other than methyl) groups [Evidence IEA];
                     GO_function: GO:0004310 - farnesyl-diphosphate
                     farnesyltransferase activity [Evidence IEA]; GO_function:
                     GO:0051996 - squalene synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]; GO_process: GO:0009058 - biosynthetic
                     process [Evidence IEA]; GO_process: GO:0006696 - ergosterol
                     biosynthetic process [Evidence IEA]"
                     /product="squalene synthase"
                     /protein_id="ncbi_M747DRAFT_363127-T1"
                     /sec_met_domain="phytoene_synt (E-value: 1.1e-06, bitscore:
                     22.6, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MEYISSALYYVFHPYQLRDILKWWKIQHNQIYRLNLGNESESRKV
                     CFKFLDQTGRSFSAVIKELHPELLVPICIFYLVLRGLDTIEDDPSISVKAKAALLRGFE
                     DVLVKDGWTYDGNRPEEKDRELLVHFHHVINEYKALKPACRLIIKDITRVMGNGMADFC
                     HKVTLNNPDKAGVMTIVEYDLYCYYVAGCVGEGLTRSFIEAQLCNSSLLDYPKLSRSMG
                     AFLQKTNIIRDVSEDHGDHRCFWPKQIWSKYVSDFADLFKPENCEAALDCSSEMVLNAL
                     EHAKDCLVYLAGLNEQSIFNFCAVPQSMAIATLELCFRNPALFERDVNIKISRGDACQL
                     MFECTQGLPGLCRIVSRYARRIKTKNSLSATNLSEINTVCDTIEKAVEELFHPEEGQTH
                     "
     mRNA            join(<10001..10071,10132..11206,11257..11533)
                     /locus_tag="M747DRAFT_363127"
                     /product="squalene synthase"
     gene            <10001..11533
                     /locus_tag="M747DRAFT_363127"
     CDS             join(<11864..11968,12038..13252)
                     /codon_start=1
                     /locus_tag="M747DRAFT_363130"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_363130-T1"
                     /transl_table=1
                     /translation="MRGIIPHSRCDTENSSTLLLSHTTVTPTCRLQQIPSITSKTLSSY
                     TMASGFAYRIDNPISEVFHFPNYEQPHLPDRREITLLSKGNREPNADPSRFLGHFLPFE
                     IIQHILLYLNLASIGKMLLVDTVSKFQVESVRPYLLLRDKAYETLHLMHRMRLSHYFTI
                     EQLYTEFTHPRCRTCNDFGPYLHLATLTRCCYNCNYHNLMYRMASVKDLCFYFGLKETD
                     LEDIPIVHNTWKSGARLVSVPQGNAIAIILHGPKGSLKITREVHRTIEGLGAAFGEWDL
                     SGPLYRGFGHQRSASVWYENGCEQLQFMATAPFPFWNKDTKTLERGTYCWACYHDWSRA
                     MSSDEHADYPPSRRAYHRSYREADLPEHFLTCAAYKACYQPMRAYPRVLRGDEYEWGDV
                     KNQFWVEYKDPNDDPGWVDFNEDVMPPPWNSNTGTVIWKS"
     mRNA            join(<11864..11968,12038..13324)
                     /locus_tag="M747DRAFT_363130"
                     /product="hypothetical protein"
     gene            <11864..13324
                     /locus_tag="M747DRAFT_363130"
     mRNA            <14850..>16151
                     /locus_tag="M747DRAFT_363132"
                     /product="PLP-dependent transferase"
     gene            <14850..>16151
                     /locus_tag="M747DRAFT_363132"
     CDS             <14850..>16151
                     /NRPS_PKS="Domain: Aminotran_1_2 (75-426). E-value: 1e-48.
                     Score: 158.0. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_363132_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="InterPro:IPR004838"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="PFAM:PF00155"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 162.4; E-value:
                     2.6e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_363132"
                     /note="EggNog:ENOG41; GO_function: GO:0030170 - pyridoxal
                     phosphate binding [Evidence IEA]; GO_function: GO:0003824 -
                     catalytic activity [Evidence IEA]; GO_process: GO:0009058 -
                     biosynthetic process [Evidence IEA]"
                     /product="PLP-dependent transferase"
                     /protein_id="ncbi_M747DRAFT_363132-T1"
                     /transl_table=1
                     /translation="METSALSQRARTVVSSRNNLMWDILKNPWCPTTKPDGYVNVGVAE
                     NALMHDYLLEYINTKLTLPAKYLTYNDGAIGAERLRRAMASFLNKHLQPFKPLTINDLL
                     VTNGVSSAIEHISWAFTDPGEGILLGRPYYGTFIPDMSLRPGATVVPVEFNDSDPFSLE
                     AVDCYERALLTFQQDTGRKVRALMLCHPHNPLGRCYPRETIIRLMQLCQKYQIHLISDE
                     IYALSVWENTVDEHTPVPFESALSIDTTGIIDPSLLHALWGMSKDFGANGIRLGVIISQ
                     NNPTLHKALQGVSLYSYSSSVSEHVAATVLEDTDFTTRYIQLNRQKMSESYAFAVQRLR
                     ENGIEYAPGVNSAFFLWVNLGKRYRELHPEQTADLGDEISDKVMQLLLQRKVFLASGVL
                     FGSEHSGWFRIVFTHPREYLEEALRRIVVALNDL"
     aSDomain        15075..16127
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_363132_Aminotran_1_2.1
                     "
                     /evalue="1.00E-48"
                     /label="M747DRAFT_363132_Aminotran_1_2.1"
                     /locus_tag="M747DRAFT_363132"
                     /score="158.0"
                     /tool="antismash"
                     /translation="GAERLRRAMASFLNKHLQPFKPLTINDLLVTNGVSSAIEHISWAF
                     TDPGEGILLGRPYYGTFIPDMSLRPGATVVPVEFNDSDPFSLEAVDCYERALLTFQQDT
                     GRKVRALMLCHPHNPLGRCYPRETIIRLMQLCQKYQIHLISDEIYALSVWENTVDEHTP
                     VPFESALSIDTTGIIDPSLLHALWGMSKDFGANGIRLGVIISQNNPTLHKALQGVSLYS
                     YSSSVSEHVAATVLEDTDFTTRYIQLNRQKMSESYAFAVQRLRENGIEYAPGVNSAFFL
                     WVNLGKRYRELHPEQTADLGDEISDKVMQLLLQRKVFLASGVLFGSEHSGWFRIVFTHP
                     REYLEEALRRIV"
     mRNA            complement(join(<16246..17196,17249..17460,17512..18461,
                     18758..18779,18951..19587,19648..>20514))
                     /locus_tag="M747DRAFT_313165"
                     /product="aconitase"
     gene            complement(<16246..>20514)
                     /locus_tag="M747DRAFT_313165"
     CDS             complement(join(<16246..17196,17249..17460,17512..18461,
                     18758..18779,18951..19587,19648..>20514))
                     /codon_start=1
                     /db_xref="InterPro:IPR000573"
                     /db_xref="InterPro:IPR001030"
                     /db_xref="InterPro:IPR003663"
                     /db_xref="InterPro:IPR005828"
                     /db_xref="InterPro:IPR005829"
                     /db_xref="InterPro:IPR006248"
                     /db_xref="InterPro:IPR015928"
                     /db_xref="InterPro:IPR015931"
                     /db_xref="InterPro:IPR015932"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036008"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF00083"
                     /db_xref="PFAM:PF00330"
                     /db_xref="PFAM:PF00694"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1169:sugar
                     transport protein (Score: 263; E-value: 8.2e-80)"
                     /gene_kind="transport"
                     /locus_tag="M747DRAFT_313165"
                     /note="GO_component: GO:0016021 - integral component of
                     membrane [Evidence IEA]; GO_component: GO:0016020 -
                     membrane [Evidence IEA]; GO_function: GO:0051539 - 4 iron,
                     4 sulfur cluster binding [Evidence IEA]; GO_function:
                     GO:0003994 - aconitate hydratase activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]; GO_process: GO:0006099 -
                     tricarboxylic acid cycle [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="aconitase"
                     /protein_id="ncbi_M747DRAFT_313165-T1"
                     /transl_table=1
                     /translation="MAGLTLPVVGTRLQIALVLLIVAPSFILFGYNQAVLGSLLSLQSW
                     VSVFPAIDTINTSGAQKSHNSTSQGACNASFQMGCLIGALSLSLYSDKLGRRKTVFIGA
                     AITVLGQALQVSATTLVQLVVGRVILGFAIGQISGTVPVWLSECASPKYRGQLGICTGI
                     FISTGYTLCNWIDLGFSYLPSSTGQWRAPLSIPFLFSAMLLVSAFTFPESPRWLISRGR
                     VEEATASLCRYRGKDAHDEMIMGEIAHIQLALEGSGTMSVLDIFDRKDKTRLLLRFWLC
                     MGLNFFQQACGGNLISVYSSTIFQNYLHMTPTMSKVLASCVLSWKTLCCLLTFWTIDNW
                     GRRLSFMVSGAGMSICMAVLAVTTGLGKITHAMAIAYVAFMFVFNFFYPIGFMGGNFLY
                     TAEIAPVRLRAAMSSLATANHWLWNLVVVLVTPVAIDTIGCWYYVIYALISATIPVCVY
                     FFYPETRHRSLEMLDRVFVDAPSIWRIVPMARGLPLGEVGTAETDTRKTEEYDRPLTYA
                     EKVLYSHLDITFDERIERGKTQLKLRPQRIACQDATAQMAFIQFMSAGLDTAAVPTTVH
                     CDHLIVSRDGETQDLARALDNHKEVYDFLESACQKYNMGFWKPGAGIIHQIVLENYAFP
                     SGMMIGTDSHTPNAGGLGMIAIGVGGADAVDVMAGLPLELQAPQVLGVRLTGQLSGWAS
                     PKDIINAVAGTLSVNGGTGSIIEYFGPGAQTLSATGMATVCNMGAETGATTSIFPYAPQ
                     MADYLRANHRHEMADAVKSIAPELQADEGAEYDNVIELDLSTLEPRINGPFTPDFSTPV
                     SRFGEAAAENQWPDMGRAASLAQQALDAGLEPKMPLLVSPGSVQTRETLKDAGILPVFE
                     RLGATMLPNACGPCCGSWDRVDMPKGAPNSIITSYNRNFSGRLDSNPATNVFLASPELV
                     IAKAFSRDLSFNPTTDSLPTPSGEQFHFLPPTSDSLPSKGYLSSDSAYAPPPANRDNIS
                     VKIDPSSLRLQKLSPFPPWPGHDFKDCAILIKTAGKCTTDHITPAGPWFRYRGHLENIS
                     NNTLIGATNAENGKVNSIRNQLTKQDGQEVPATARHYKENSVPWVVIADHNYGEGSSRE
                     HAALQPRYLGGVAIIAKSFARIHEANLKKQGLLALTFDNEKDYERIRAEDRVSILGLRE
                     GEFVPGSTLRLVVNGGEWEAVLRHSFTEEQIGYFRSGSALNVMAGK"
ORIGIN
        1 cttaggcttc ttgttctgga accctacaga ttcagcaatc tgatcaaacc agcccctttg
       61 tttcgccttc attgcgtccc attcatcgta tgctggcttg atctcaaatg tccgggcggt
      121 catcactagg actgtccgca tctcgttgta tacaagagtc tgaccaatgc agttgcgagg
      181 cccttgctca aacgggcgat atgcggctgg atcgggatat agttcgtggt ctgcatccac
      241 cagccaccgt tcggggagga actctcttgc tcgtggccat acccttgggt tgagatgtac
      301 cgcctggtgt aagacggaaa cgctgagatc atccgccaag ggatagcgat tgccgtgcct
      361 atcggtcagt gacaaaccat cgatgccttg acgcatagta cttgcggggg tatagagccg
      421 aagagtttct ttgatgactg ccatggtata tggacatttg ttcagcagtg aaggctgttc
      481 gcagagtagc tgcaccgcag cggaaggatc tggtccgaat atgcggtcat gttcttcccg
      541 gacttgggtc aaagcttcag ggtgcttgga caagaggtga tacacatagg cgatactgct
      601 tgacgtggta tcagttccag cgaagaggaa cagtcgaatc tgatatgtta cattttttgt
      661 aaagtcgtca tctaactcgg ttgcctcaga gatctcttca ttcttattct ctaggtatgc
      721 ctccaaggct agagtgagga tcgatttggc acgcttggaa cgggttgata catcccgttt
      781 tacgtgcttg atctcggaaa atcggtcatt cagtgcttta cgaatccatt tgtccgcgac
      841 gcggccatag tatccctgaa ttaaagggcg tagtgggttt gcccgtacgc ggggatccca
      901 gaacgaatgc catttggtga tttgaccaag agcggttgca atgacgttgt cagaattttg
      961 atggtcaacg tcggcatcac tgctcaggtt agcaggtggc ccagaaattg caggaggata
     1021 aactaacagg gtcactttga ggattacatc catagttaat ctggtggtca gatcatccaa
     1081 ggcaaacatc tctccagaat cggctttttc gcgtagttta tcgcaaaaga cactaactga
     1141 tttgataact tcaggcagaa gatcctgcat gctacctgca ctgaaccccg ggttgaagat
     1201 tgatctccaa ggcttccact cagcgttccc tacagaaatc atactaggcc cgcctgtgat
     1261 cggtcgcatg aaccggtcgt gtataactgt tttggggagg ttaaatttag tggtaacctg
     1321 tgacgctgct tccggataga acactatgta ctgtgcgggg gacatgggcc agacatccaa
     1381 taggaagatc tctgtgtcgg tgtattccca agccaactct tgcgtcgcaa gtataacgtt
     1441 ggcatcgggg ggcaaacggt tgagataccc cgacaggaca aacatgtgac cagttagcca
     1501 gttccatcct ggtggcattg cctaaacaaa atgtcaatca cacaagcatc tcagtgaagg
     1561 tgaagtttct agttactatg ccttgtttgc ggagctggtt gattttggac cggtgttggt
     1621 aaagcgcatg gagtccatat gcgacagcgc ttacaacaac cggtaagcaa atggtcagca
     1681 acaggttgat gaaagccatt ggtgcagact tgatgtccct cgcttccacc aaggcagaaa
     1741 cggaggaagc agtttgttta ctttagtgat ggagtgttgg aggggatctc gggcaggagg
     1801 cggtgagatt aggcgggcag ttgcctaaaa gggtaaccgg gtaacactcc aacatcttcc
     1861 cagcctcagt cgctggtatg gtgtgcagac aacaacaatg cttataatag catcgtgcgg
     1921 agcctcaagt gtcctgagag cccttgcgga ggatatcaca gcataagcca gaggctgtgt
     1981 ctggaatgat gtccagataa gcccgattca aaaccaccgc tggtctgctc gaatgcgcag
     2041 ttccccacta caaatagtga ctgatgatgt aaagaatcat cttgtcagtt gtctcgctgc
     2101 attatccctt gcttgtatca taccagagca cggccgcagt tcctcgacct tactcagcac
     2161 ctccggcttg atgccccgtg tggatctcct ccagtggtgg atgcatatgg cgaagcagca
     2221 aaattgatgg cattggtcga gacgagtatg tagatctgaa cggagccccc aatctactgt
     2281 taaggctgta cgttaagaca tggcggttac tattcaaagc tccgagcgac gctgcttgtg
     2341 aagagggata tgccgataaa cactgtatag atagtgaggt gaagagggtc tttgaacata
     2401 agcaggaatc tatttcctgc tatccttcaa gtgaacttat atatcaaatc gtctggttaa
     2461 ctacggaggt ctttggtggt catgatactt ggacagggat gacgctagtc aggcgcggaa
     2521 gggatatctc ttcccaccca ctgatggcag gcacgcgcaa gaggctgagc tacatggctg
     2581 ttgactagca cgcgtccaaa ctgttgagaa ctggaacaaa atttatcaac cccattatca
     2641 acttcaatat cgctcattca aagtcctcag cgctggctgg gaatcgaggc cgagtttccc
     2701 aagggagact aagaatctga aggcaacttg agccccttgc ttcttctggg aggcattgtc
     2761 aacttcctga ggtcgatcaa atgcagtcag cataaattat gtaggaggag atccagtgcg
     2821 ccgcccaagt ccccgcacat ccaacccaga caattcgtgc aaccacagag tctgacagcc
     2881 cgtctctaca taaagcggtg gtcccgtctg tgaggtgcgt caagaattgc acctgcacct
     2941 ctaaaggcta tgcctcactc atcccggaaa cctgcaagat ggacagcgca gcgctgaata
     3001 tcacttccag tcaagcttct cagaccccgc cggccatagg tgatatcggt cggattaccc
     3061 agcggcaata tggcgtaagg ctagtccaag cataattatc cgaaagtata actctaacga
     3121 aagatctatg attaccagat agcagttggc gttttctttg cgttagcatc actgtcgttc
     3181 tttggtcgca tcttcatccg actcttcact cgacgacgcc tctatttgga cgatgctttc
     3241 cttagctttg cttttaccac actgttgata ggaacagtac tgggctttct ccgcgcatac
     3301 accatctact ttcagatggc agcattggaa ggaaatgttg gcgcagtcct ctttctcgcc
     3361 tcgcatttaa atgaacatgc caaagactat ggcttcaaca tcgcctttat agttcttctc
     3421 tggaccacag tttttgctgt caaatggtgc tacctggcat tcttccagcc cctcctggtg
     3481 ggaatgtcac gctggtttat tatttattac cgtttcactg tcgggctgtc tgttatctcg
     3541 tggatcttga gcgccttcgt cgctccgatc gttccttgcc cgtacacagg aatgaaggca
     3601 atttgtaagc acctctggtc agcgataggc tcctccacta actatgtaaa gccaaatgct
     3661 ttcccacttt accagtccca aacagcacgg ttcttgcaat gatttggctt ccaccaattc
     3721 tggatgcggt cactgatctg atgagtatgt cacctaacca aacaaagact agctataact
     3781 gaccttgccc agtaattagt attccaatcc ggttgctcta taaggtccaa ttgcgaacct
     3841 tgacaaaact gggacttgga tgcttcctgt gtctctcgat cttcatgtgc acgtgctcca
     3901 tcattcgcac tgcaggcaca tggtatcacg ggcttctcga ctacccatgg caggtattct
     3961 ggctgcattt ggagggatgt atcggagtca ccatgggatc tatcaccgtc taccggtcca
     4021 ctttgatcgg atcaagtgag gtttcaaccg cattcaagag atactttacc cggatcaagg
     4081 acgcggtttt ggggtcgtca agtggcacag cacaagcgcc accaacagag gaaaacaaga
     4141 ctcggacacg tcaatttgga ctgccgtcca ttccacaagc aactattacg gggttgcgca
     4201 cgtggttcgg tttctccagg agggatcctg ccgcttccaa cgatgcctcc gggatcacta
     4261 gctttaacag cgatatcgat taccatactt tgttgaaagc ccccaaggca gcggcgagtc
     4321 accctcaatg agtcttaagc ttgattgttg caatttcttc tccagacaga gggcaggacg
     4381 acactcgaat gtatttgatc aatctagatc tcaagatgat ggttgggtgg taggtaggag
     4441 gcggtggtgg tcagagacca cgtagacaga ggtggcgaag gatcaagcga tccctggcta
     4501 cagcgcaagt ctcaacacag tattactggg atcggagtta agatgtgcct ttccatatat
     4561 gatatacgcg gggataggat atctccagca caacaataag acgaagtgaa ggatggatcg
     4621 accgcggcaa acacccggct taagtccgcg gacattgggt gccgctttgg gcttagtggc
     4681 tgacagccgt aatatatagg atcatcagga acttgtatta agagaactag acagcctgct
     4741 tctgctttac aaataacacc tttcgattca gagaatctga agtctttctc tgacattact
     4801 atcttaccca caatggcgtc aaaagacctc cctccttcga ccgctccctt ctttcccaac
     4861 gtcttctttt ataaccaatt ctgtgccaaa cccaattggc cacccgcaac cacaaatctc
     4921 tctggtcaag tggccataat caccggaggg aatactggcc tgggatttga gtgtgcattt
     4981 cagcttctat ctcttcagct tagccacttg atcctcgccg ttcgctctct cgagaagggc
     5041 gaagccgcag cggccaagct tcgggccgtt aatcccacgt caacaataga tgtctggcca
     5101 cttgacatga gctcatatga ctccatacaa agctttgcaa agcgggtcga aaaccacctt
     5161 tcccgcctag atatcgctat cctcaatgct ggggtgagac aagcccagtt caccaccaat
     5221 ccaagcaccg gccacgagga aaccattcaa gtcaactatc tctccaccat gcttctcgct
     5281 atcctcctcc ttccaagctt gagggacaaa tctccgaaag gagtgccagg gcgattaact
     5341 atcgtcagcg cggcactatc gctcctgcca agcttaccaa atgtgaagga tgcgccactt
     5401 ctgaagttgt tcgatcgtcc agatacatat gatgccaatg gcatttactg catgtcgaag
     5461 cttctcgctc atgcgtttct ctacaagttg gttgaatatg tcggtgcaga tgatgtgatt
     5521 gtgaacctgg cagatccggc cttcgtcaag ggcactgacc tgagccggga ttcgcctggc
     5581 cttgcgaagg ctgggctagc ggtgtttggg gttttgacgg ggaggacagt caaggttggt
     5641 gcatcgacgt ttattgatgc tgccgtgttg aaggggaagg agtcgcatgg gtgcttcctt
     5701 atgagttgga agattgaacc gtaagtattc ccaactttcc tttgaatttt tcacgtcatg
     5761 gctgacacac gtatgttcag gtttaatgcg tcattgtata ctccagaggg gaaacaatct
     5821 attgaacagc tgtggcagga gacgatggat gaacttgatt ttgctggtgt tcgaaggata
     5881 cttgagactc tgtaaatttt tagaagggag caaacaaata aacgctcagt cacctctttt
     5941 aatgcttgtt taccaagctc gattcggact tgctatgtct gcaaaattat aatgttggca
     6001 gcaacagact gaaattggcc ctagggattg atgaaaaatt ggatcggcaa agtgcagaag
     6061 aaatccccat ctgcagcctg tgctttatga ggatccattc aaactttgaa tatgttctgc
     6121 ataagcatac ctaatatagt acaataaaag gaggtttcat aactctatga cgttgaagaa
     6181 gaccgcatgc ctcttatgat ctccagatca atcgggtagt ggggatagga ccccacatgg
     6241 gcccacttgg gcagcatgag tgggcatgag tcattctgag tcgacatgag aacatcaaat
     6301 catgatcatt gcacagccca ctctccagcc caaacagctt gcagtttcca gaattagcca
     6361 tggaaagact agaaccgtac actttagcag acatctctcg cctaaagaac cccaggtttg
     6421 ggaagcctgc cccacccgag attaatgtta cacgtgacgt tacctcccag gcccagctat
     6481 ataactcaac ctcaatcgcc atgaatatca cttaaactcg ccatccaaag agctcaattg
     6541 cacacacttg tcgattatta ccttcattcc actcacaatt aataccaatt caactctcta
     6601 atcattatat gaacccccca ccatccacaa tggcaaccac aaccaccacc tcaaacccca
     6661 ctccaacaat gacctactac gacatcgcca tgcgacctcc agtaacccgc aacgccgcag
     6721 ccgtaaatcc ctggaaagcg cgactcgcac tgaatttcaa aaacgccccc tactccacaa
     6781 cgtgggtcaa gctccctgaa gtatccaaag tgcgccgcag cctgaacctc cccgcatgtc
     6841 gcaaattcgc cgacggcagc gacttctaca ccctccctat cctctccgat cccaccacga
     6901 actccctcat cggcgactct ttcgatatcg ctgtctacct acaaaagacc tatcccgcct
     6961 ccggtggcgg ggatctcttc cctccgcaga acctggatta tgaattgaaa gaggagctga
     7021 aggtgctggt accgctatcg gagaggaacg atatcgaata tgcggactat gcccggttta
     7081 ataataatgt cgatgcggcg tttagtgtgc ataccatgtt gatggtgcag aagatgccgt
     7141 ttgatccgga gacggcggag gagagtaagg cggagtttgt ccggcgggcc gggcttaagt
     7201 cttgggatga ttttacactt gagggggaga agagggagca ggtgttggct tcgttccggg
     7261 agatgttgaa ggatctggcg agaatgtttg agagagatcc cagtgggccg tttttgttgg
     7321 gggagaggcc gagtcatgcg gattttattg tcggagggtg gttgaggatg tcgagggtta
     7381 cgctgccgtc gacggagtgg gagcagttga gggagtggca tgggggtgtt tttgggaggt
     7441 tgcatgatgc gttggatgtt tatgctgagg ttaaatagac tggtgaaaga tatgaataca
     7501 agatggatag aaggaaaagt cctgtacaac aattgaatat atttcttatt cactcgtgga
     7561 gtcatacaaa gcctcatgga acagcaagga atctttataa tccgttttca gaatatagct
     7621 gtggccacca cccagaaata tcttccccga agatatcttc ttcaaaagat gagaagatat
     7681 ccatccccaa gcctccgttt aacagagaca cgtcccaggc cgcctgccct gacagcaacg
     7741 ttttcacacc tggaatcccc attgagccgt tccctccaga ggtaggggtc tgggcgtctg
     7801 ttgactggcc atagacagct agtaagcaag tcctcatcct attcacccag gctaatgatt
     7861 tcgcaaccac gttttcgtga tcatcaccct cgtcgctggt gggttgtacg ttgctcaggt
     7921 tctcggcggt cctgtcgaga atagacgtaa tatctacggt tcgtcgaacc atattcacat
     7981 cccacgccgg atcttcgagg gatgcgagtc gaatgagcgt gagaataact gttcggaatt
     8041 gcctccagag aaagaagggg aagtatatgt agtctgttgg tttaaagtta aacataatgt
     8101 ccactgcgcg tttcgctgca ttgagacaag tgagaagagc ctccatgctg ctggtatcag
     8161 caagaagagg tgtctgtcgg aggcgtataa agataaggtc attgatgcat atttctgtgt
     8221 gcagggccat tgcttcaaga acctctattg aattcgaatt agagttagcg tgcatttctg
     8281 tcagctattt gtgggttgaa cgtactatcc gtggccaggt gtggtggaaa tgatttcctt
     8341 gtctccgcta actgggtgct gagggcagac atgtatggag agataagacg cgtactttgt
     8401 tcgcagtcgg catctcttaa ttgtatccgg agatcagtga ccttgctcgt tatgcgttga
     8461 agcttgatca tttgcacgag aagatcgtct ccaggaagat tccttaaacc ctgtatcatt
     8521 ttcaagcatt cttccatgta tggtgaccag gccaagttct ccccgactgt ctggaatgct
     8581 gcaatactga tcgtgctatt agcggcattc taaatatttc aaagaagtgc taaccatgaa
     8641 gtgagaaagt agcaagctaa tgccgtccgt gcattttcaa gacccctcgg ttgatatgtc
     8701 ccagtagctc cctggatttg ggctgctatg ggtcgcggaa atatatgact caaattgccc
     8761 tctccacaat gccgacttcg aagttccaga tctaccgtca aagcagtgca cagatgagac
     8821 aaaatagtaa gaagtgatcc catagagaac cgaaagtgtc ccctatatat tactatcagt
     8881 catgcggata gcaaagtgtg ggaagaaaac ggaccaaccg atgaagcaga ggagaccata
     8941 taatagatcc gtcgtacact tgccttctac aattacctca cgagcggcaa cctctcgaac
     9001 cgcctttccc aggttgctct gttccctggc atttgtagat gtcacagcca ttatacatag
     9061 ccagaggaat ggtgactctc gatacaactt ttccgaagtc aaaccgttct cgagatatat
     9121 aagagggagg aatttggtgt agtggttgca aaatgtcctc aaacgttgtt ttgcgttgcg
     9181 agaagttggc tccacgccag ccggaagact atatgggaat agacacgagc tgtctgatga
     9241 aggaggtgat cttggtgatg aacaatggcg agacttgcca tgatctgtag ctactctatc
     9301 aagatcacca acaagcggtt gtgcatggga cccacgatct gcaggcactg aagcgtgaga
     9361 cagagctgat gtgagggacg cggatgatga tgctgtatct ccgatctcag ggctaccctg
     9421 gcgagctttt aataatgaaa cgagcccatc taatttctgc tctagacgag cggcttgaga
     9481 gccgttgggc ttggagccac gcctgcggac ggtaggagaa ggtctgcatt ctacttttag
     9541 acgaaagcat ctgaccatga atatgagcca atcatcacca atagtatttt cgaaaattac
     9601 ctttcacatc catctccatt ggctcgcagt atgcacttgc gttttacgcg ggcacagctg
     9661 acgcacgctc ggccatatgg ggccgccttt ccacgattat gtgctatatc ttccattcaa
     9721 tggggcgctg tgaagatgga tataattgtg aagctgtata gtccaatatg aggtctggcg
     9781 tggctgcaac gcgaatatgg tgtctctgga attggctgaa ccccccagcg gacggatttc
     9841 gggaggttga aaattcgaaa tccgcttcgg caactaaaat agcgggttgc gaatcccgct
     9901 ccgctccgct tccactttct atacccttaa aaggcccgga gcccaaacca tgagtatcat
     9961 cgttaccaga ggtgtttctc ttatttatcc acatatgaga atggagtata tcagcagcgc
    10021 tctctactac gtctttcatc catatcaatt gagagatatt ctgaaatggt ggttatcact
    10081 cacccattaa cctactattg atagctgacg ggaggcatgc tacggtcata ggaaaatcca
    10141 gcacaatcaa atctatcgat tgaatctggg gaatgagagt gaatcccgga aggtctgttt
    10201 caagttcctc gatcagaccg gccggagctt cagtgccgtt atcaaggagc tccaccccga
    10261 actgctcgtc cctatttgta tcttctacct ggtcctccgt ggtctcgaca ccatagaaga
    10321 cgacccttct atttctgtga aggctaaggc tgccttgctt cgcggcttcg aggatgtatt
    10381 ggtgaaggac gggtggacat acgatggcaa ccgtcccgaa gagaaggacc gcgaactgct
    10441 tgttcacttc caccacgtta tcaacgagta caaagctttg aagccagcct gcagacttat
    10501 tatcaaggac atcaccaggg taatgggtaa tggaatggcc gacttctgtc acaaggttac
    10561 cctgaacaat cctgataaag ccggtgtcat gactatagtc gagtatgatc tgtactgcta
    10621 ttatgttgcc ggctgtgtcg gcgagggcct tacccgctcc ttcatcgaag cgcaactttg
    10681 caactcgtcg ttgctcgact acccgaagtt atcccggtca atgggtgcct tcctccagaa
    10741 gaccaacatc atccgcgacg tcagtgaaga tcacggagac caccgttgct tttggcccaa
    10801 acagatatgg tctaagtacg tcagcgactt tgcagatcta tttaagccag aaaattgtga
    10861 ggcggcctta gactgcagtt ctgagatggt tcttaacgca ctagaacatg ccaaggactg
    10921 tcttgtctat ctggctgggt tgaatgagca gagcatcttt aatttctgcg ctgtacccca
    10981 gagcatggct atcgcgacgc tagagctgtg cttccgcaat cccgctctgt ttgagcggga
    11041 tgtcaatatt aagatcagca gaggtgatgc atgtcagctg atgttcgagt gcacacaggg
    11101 cctgccgggg ctgtgtcgta ttgtcagtcg atatgcacga cgcatcaaaa ccaagaattc
    11161 attaagtgcc accaatcttt ccgagataaa tacggtgtgc gatacggtat gttatctcat
    11221 ttatacttca gagtgagcga gtcctaacaa ccatagattg agaaagcggt cgaagaatta
    11281 tttcatccgg aagaaggaca aactcattag tgcaatgagg atgaacagtg atagtggatg
    11341 atatgagatg cactactgct agatatcagg atgggcaacg gtaaagagtg tactcgagga
    11401 atccacatta tggaatcact ggaagaatat cctacatctg aataataatg taagggcgtc
    11461 aacctagcat acctggttga gctctaatgc gccttcgcga gcatcttgtt gaacagaagc
    11521 ctacgaatct tggtcaatac ccgtattgtc cattttaaca acaatctgag cctcccctat
    11581 cagcttacac aaggaaatcg ggccaacggc ggctgtatca atgcagctag cagcaatctt
    11641 caaatagcga tatattggac taactgtaga cgttggcagg aaatgtcgaa gatctttata
    11701 aacaaccttc gtagtatatg ataccatctg cagtccacag tagctcattg ggagttgaag
    11761 tatttacggc attgtgctga gtcgtcaatc cacagattgg atttcggccc aagttgttgt
    11821 ttgcagttgc acgtactggt gctatcatag tgttgccgcg acgatgcggg gtataatacc
    11881 tcattcacgt tgtgatacag agaattcctc aactctccta ctatcacata caactgtgac
    11941 tcctacgtgt cgacttcaac aaatacctgt atgaacctgt tctctatcac accagattag
    12001 ccatttggaa ataatctaac tcactttctc aatctagtca ataacttcta aaaccctctc
    12061 gtcttacacg atggcatccg gctttgccta tcggatcgac aacccgatca gcgaggtctt
    12121 ccattttccc aactatgaac agccacatct cccggaccgg agagagatta cactcttgtc
    12181 taagggcaac agggaaccta atgctgatcc tagtcgattc ctcggtcatt tcctgccgtt
    12241 tgagataatt cagcatatac ttctctacct caacttggcc agcataggga agatgcttct
    12301 agtggatacg gtatcaaaat tccaagttga atcagtccgc ccgtatctct tgcttagaga
    12361 caaagcctat gaaacattgc atctaatgca ccggatgcgt ctctcccact atttcaccat
    12421 tgaacagcta tataccgagt tcacccaccc tcggtgtcga acctgtaatg acttcggacc
    12481 ataccttcac cttgcaacgc tcacccgttg ctgttacaat tgtaattatc acaatctaat
    12541 gtacagaatg gccagcgtga aggatctctg tttttacttc ggtttgaaag aaacagatct
    12601 cgaggatatt ccgattgtcc acaatacgtg gaaatccggg gcccgtcttg taagcgtccc
    12661 tcaggggaac gctatagcta tcatacttca cgggcccaaa ggatcattga agataacacg
    12721 tgaagtacat cgtaccattg aaggtttagg agcggctttc ggagaatggg atctgtcagg
    12781 gcctctatat cggggttttg gacatcagcg gagcgcgagt gtttggtatg aaaacggctg
    12841 cgaacagtta caattcatgg ctaccgctcc attccctttt tggaataagg acacaaaaac
    12901 cttggagcga gggacttatt gctgggcttg ctatcacgac tggtcaaggg ccatgagctc
    12961 tgatgaacac gcggattacc caccaagtag gcgggcctat catcggtcgt atcgagaggc
    13021 cgatctaccg gagcattttc taacgtgtgc tgcctacaaa gcctgttacc aaccaatgcg
    13081 ggcttacccc cgggttctcc gtggcgacga atacgaatgg ggagacgtga agaatcaatt
    13141 ttgggttgaa tacaaagatc ccaacgatga ccctggatgg gtggatttta atgaggatgt
    13201 aatgccacca ccatggaatt caaacacggg gaccgtaata tggaagtcct gaagttatcc
    13261 aataaatagc tcacgcggcc cctatggttt actacattca tagtgatagc tgcagtggcg
    13321 tgcaatcagt actacaaatt aatgcccgtt gtcttctcag actagttact aatctgctat
    13381 agcagtttaa attgaggccc tagcttgtta tcattcttct cgcatcaaaa atattgtaag
    13441 ccgtcaaacc agatgtaagg ggtatctctg tatgttgaca ttctatgccc aagctagcga
    13501 gagctcctgg atggttaagt aaaacacaca cacttcaact acgtggttca gtgatagtat
    13561 tcgttggcca tatattctat ctgttggtag ctgactatat tctggacaaa tgacttgtta
    13621 tcccggccta ttgagtctct tctggcaaga ttcgaacgtg gctgatgacc accgccccca
    13681 acccctcacc ccccaggtac ctccatgacg acgactagtg catgctagat gggacacacg
    13741 ttaactgatg gttgctgggg attaagaacc ctcatgtgga acttattggg ctccggatga
    13801 tagggggatg ggctatcgct tctttcgatc ctggtgctgg ctattccaga taaatgagga
    13861 gcatcaggca gatgtgacgg ttatgacacc ggcattgagc tattctcgaa ttgcctcaag
    13921 aatagctccc ttctgcccag tcaatgaatt tacgtcgtcg gtgtataccc ccaagatcca
    13981 catctcctat agaagtttgg ccctattgat catcctccat gttacgctcg ttatcccagt
    14041 caaatactga aatgctttcc cactagccct gaattccggg gaaagagaca ggactgagcc
    14101 cataccaaaa gaaagtatcg ccacatgctt tgagacgcat tcaccatact ggccatctta
    14161 gacgcgatgt gtcacagagc ttatcaggca tactatttgt ccttctacct tacctgtctc
    14221 ccgcaaggga ttgccggtga tcgcccctct ttaggctggc attcctgtcc tcaatgcgga
    14281 gtaaaggagg tgattatcac ccacatcatg aagcatccac aaattgacaa acagaaaccc
    14341 gtgatgaccc acttcaccga gctcggcctg ccgaaccacg ccctccggta taccacacaa
    14401 gttcttcatc tcccgtaaac tttctccacc agcgcatcca tggtgggaat attaggttcc
    14461 cgaccaacct tgagtcaaca ctaagcgaac caccaaacac aaagcagaat ttggttcaca
    14521 ggcttcactg tgatgtaatt cactgagctc ctgggcgcac agaagcagtc tacatctatg
    14581 gaaagtaagg tgtccacact gcgtccagcc cacttccgta tcaacagtat cggtaccatt
    14641 accatccctt gaataaccta acatctcaac tacttatcca gaacacctca gtgttttctg
    14701 gaactgccaa gaacccgcgg atatccgtaa catccagtgg agtcaacctc ctcacgtgtg
    14761 tcaaatcctc acttctcttc tggctcccca agcccatatt ttaccacaaa cacaccccaa
    14821 tcgtagcata cagccctgca tccaacaaga tggagacctc cgccctctcc cagcgagccc
    14881 gcacagtcgt ctcctcccgc aataacctca tgtgggacat cctaaagaac ccatggtgtc
    14941 ccacaaccaa acccgacggc tacgtgaacg ttggggttgc cgaaaacgca ctgatgcatg
    15001 actacctcct cgaatacatc aacaccaagc tcaccctccc agccaaatac ctcacctaca
    15061 atgacggcgc aattggtgca gagcgcctcc gacgcgccat ggcatctttt ctgaacaaac
    15121 accttcaacc attcaaacca ctgaccatca acgacctact cgtcacaaat ggcgtctcct
    15181 ccgccatcga gcacatctca tgggccttca ccgaccctgg cgaaggcatc ctcttgggca
    15241 gaccctacta cggcaccttc atcccagata tgtccctccg ccccggggcg acagttgtcc
    15301 ctgtagaatt caacgacagc gatccattca gtctcgaggc cgtggactgc tacgagcgcg
    15361 cactgctcac gtttcagcaa gacactggcc ggaaagtccg cgccctcatg ctctgtcacc
    15421 cacataaccc gttgggccgg tgctaccccc gggaaactat catccgtctg atgcagctgt
    15481 gtcagaaata tcagatccat ctgataagcg acgagatata cgctttgtct gtgtgggaga
    15541 ataccgttga cgagcacact cccgtgccat tcgaatctgc cttatcgatc gacacgaccg
    15601 gcatcattga ccctagttta ctccatgcgc tgtggggaat gagcaaggac tttggcgcca
    15661 atggtatccg tctcggagtg attatctctc agaacaaccc cacgcttcat aaggcgttgc
    15721 agggcgtctc gttatatagt tattcctcct ctgtctcgga gcatgtcgct gctacggttc
    15781 ttgaagatac agatttcact acgaggtata tccagcttaa ccggcagaag atgtccgagt
    15841 cgtatgcgtt cgctgttcaa cggctaaggg agaatgggat tgaatatgct ccgggtgtca
    15901 attctgcgtt cttcctttgg gttaacttgg gcaagcggta tcgcgaacta catcccgagc
    15961 agactgcgga tttgggtgat gagatcagcg acaaggtgat gcagcttctc ttgcagagga
    16021 aggtgtttct ggctagtggg gtgttgtttg ggtctgagca tagtgggtgg ttccggattg
    16081 tgttcacgca tccgagagag tatctggagg aggcgttgcg gaggatagtg gtggcgttga
    16141 atgatttatg atatggttag agtatcacat agcatacaaa tacacattgg ctatagacaa
    16201 attcatcaac aaaccaccac acagcccatc atctagacac ttcaactact tccccgccat
    16261 aacattcaac gcactcccac ttctaaaata cccaatctgc tcctccgtaa aactatgcct
    16321 gagcacagcc tcccactcgc ccccattaac taccaacctc aaagtgctcc ccggaacaaa
    16381 ctccccctcc ctaagcccca aaatactaac ccgatcctca gccctaatcc tttcataatc
    16441 cttctcattg tcgaaagtca gtgccaacaa cccctgcttc ttcaaattcg cctcatggat
    16501 tcttgcaaat gacttcgcga taatcgccac accacctaga tacctcggct gcagcgccgc
    16561 atgttcccgc gaactgccct ccccgtagtt atggtcagcg ataaccaccc acggcacgct
    16621 gttctctttg tagtggcgtg ctgtagcagg cacttcctgt ccatcttgct tcgtgagctg
    16681 gttccggata ctgttcacct tgccgttctc ggcgttggtt gcgccgatga gggtattgtt
    16741 ggagatgttt tctaggtggc ctctatagcg gaaccacggg ccagcggggg tgatgtggtc
    16801 cgttgtgcat ttcccggctg ttttgattag gatggcgcag tctttgaagt cgtggccggg
    16861 ccagggtggg aatggggaca atttctggag gcggagggat gacgggtcga ttttgacgga
    16921 gatgttatcc cggtttgccg gtgggggtgc gtaggcggag tcggaggaga ggtagccctt
    16981 tgaggggagg gaatcgctgg ttggagggag gaagtggaat tgctcgccgg atggggttgg
    17041 gagcgagtca gttgttgggt tgaaggagag gtcgcgggag aaggcctttg caatgacgag
    17101 ctcgggcgat gctaggaaga cgttggttgc tgggttggaa tctagacggc cggagaagtt
    17161 ccggttgtag gaggttatta tggagttggg ggcgccctaa tatatgtcaa aagacagtct
    17221 ttcggtaggt gggatggcga tactatacct ttggcatatc aactcgatcc cacgacccac
    17281 agcatggacc gcaggcgttg ggaagcatcg tcgccccgag tctctcgaag accggcagaa
    17341 taccggcatc tttcagtgtc tcgcgcgtct gaacactacc cggagacacc aacagcggca
    17401 tctttggttc cagtcctgca tccaatgctt gctgggcaag actagctgca cgtcccatat
    17461 cttcaaacga agagttagta caagatccaa tcaaagccgc cgtcaattca cccggccact
    17521 ggttctccgc cgcggcttca ccgaaccgcg acaccggagt cgaaaagtcc ggcgtgaaag
    17581 gtccattgat ccgtggctcg agagtggaca aatcgagctc aataacatta tcatactcag
    17641 ccccctcatc ggcctgcaat tccggtgcaa tgctcttaac agcatcagcc atctcatggc
    17701 gatgattcgc acgaagataa tccgccatct gtggcgcata agggaagatg gacgttgtgg
    17761 cacccgtctc cgcacccata ttgcaaacag ttgccatgcc tgtggctgac agagtctgcg
    17821 ccccaggtcc aaagtactca ataatggatc cagtacctcc gttaacggaa agcgtcccgg
    17881 ctacagcatt gataatatcc ttcggcgaag cccatccgga caactgcccc gtcaaacgga
    17941 cacccaatac ctgcggcgct tggagttcca gcggcaatcc agccatcacg tctactgcat
    18001 cggcaccacc aactccgatg gctatcatgc caaggcctcc tgcgttggga gtatgagagt
    18061 ccgtcccgat catcattcca ctagggaagg cgtagttctc cagcacaatc tggtgaatga
    18121 ttcccgcgcc gggcttccag aaccccatgt tgtatttctg gcaggcagac tcgaggaaat
    18181 cgtacacttc tttatggttg tccagcgctc gagcgaggtc ctgtgtttcg ccgtcacgac
    18241 tgacgatcaa atgatcgcag tggactgtgg ttggtacggc cgctgtgtct agtcccgcgg
    18301 acatgaactg gataaatgcc atttgggctg tcgcatcttg gcatgctatg cgttgcgggc
    18361 gtagtttgag ttgggttttg ccgcgctcga tgcgctcgtc aaaagtgatg tcaagatggc
    18421 tgtaaaggac tttttcggcg tatgtgaggg ggcggtcgta tctatgatgt ggatattagt
    18481 aggggtctaa taatgcagcg taggtgcgaa gtgagtagct accgctttct tagtgattgg
    18541 atggcagaag gaaactggga gatgtttatt ttatgttgtt caagtcgact tattggcact
    18601 tgggtgtggg aggcatagcc tctggctaac ttgggacagc tcactcgtgt tctgaccatc
    18661 ttgatgatgc attggtaaac aagagtgatc tattggataa gacagtagat ataaatcaca
    18721 agggtctatg taacatctcc agctgtggct gatttactcc tcggtcttcc tagtgtcagc
    18781 ttcggatggt tccgtcggct gggccgatgg gcatatcgca tctcttctac ccgaggaaca
    18841 actaattaca atagcaacgc tgtccagcta atccatctag acatactccc gcatctcaac
    18901 attaccatct atatcctctg ccttcttttc ctcgcgcagt gtatctccac tctctgctgt
    18961 gccgacttct ccgagcggca accccctggc catcggcaca atccgccaga tagaaggggc
    19021 atccacaaac acccgatcaa gcatctccaa actacggtgc ctcgtctccg gatagaagaa
    19081 gtacacgcag accgggatag tcgcagatat aagcgcatag atcacatagt accagcatcc
    19141 aatcgtatct atagcaactg gcgtaaccag aacaaccacc aaattccata gccagtgatt
    19201 agcagtcgcg agggaggaca tggccgctcg cagacgcaca ggcgcaatct cagccgtgta
    19261 caggaagttg ccacccatga agccgattgg gtagaagaag ttgaagacga acatgaaggc
    19321 aacgtatgct attgccatcg catgcgtgat tttgcccaag ccggtggtga ccgctagcac
    19381 ggccatgcag atggacatcc ctgctccgct taccatgaag gatagacggc ggccccagtt
    19441 gtcgatagtc caaaacgtta atagacagca gagcgttttc catgatagta cacaggacgc
    19501 caggacttta gacatggtgg gtgtcatgtg taggtaattt tggaaaatgg tggaactata
    19561 gacggatatg aggttgcctc cgcaggccta atggattagc ggtggtacat ttggagagcc
    19621 aagtgctata ggagccgcga tactcacctg ttggaaaaag tttaacccca tgcagagcca
    19681 aaatcgcaac aacagacgcg tcttgtcctt gcgatcgaaa atatccagga cggacatggt
    19741 cccactgccc tctagagcaa gctgaatatg ggctatctcg cccataatca tctcatcatg
    19801 cgcatccttt cctcgatacc gacagagact tgcagtagct tcttcgaccc ttcctctaga
    19861 gatcagccaa cgaggcgact ccggaaacgt gaaagcagaa accagtaaca ttgctgagaa
    19921 gagaaagggt atagagagcg gagctctcca ttgtccagta gaagagggta gatagctgaa
    19981 tcccaaatca atccagttgc acaatgtgta gcccgtgctg atgaaaatac ccgtacagat
    20041 accgagctgt ccgcggtact tgggagaggc acactccgag agccagacag gcacggtgcc
    20101 gctgatttgg ccgatagcga accctaggat aactcggcca acgaccaact gaaccaatgt
    20161 ggttgcagag acctgtagag cctgaccgag gacggtgatg gcagctccga taaagactgt
    20221 cttacggcgt ccgagtttgt cgctataaag agagagggac agggcaccta tcagacatcc
    20281 catctgaaac gaggcattgc aggcgccttg ggatgttgag ttatgggact tctgtgcccc
    20341 cgaggtgttt atggtgtcga tggctggaaa tacagagacc caactttgga ggctgagtaa
    20401 actgcccagg accgcttgat tgtatccgaa gagaatgaac gaaggggcaa cgataagaag
    20461 taccagagcg atctggagcc gggtaccgac aacagggaga gtaaggcctg ccattttcac
    20521 tttcattccc tgcttgacct ttggttcaga gacttactag gcggcttaag tactttccgt
    20581 ctgatccccc gtggggaaga ggatgtggag tcaaggaaga aaaagcgggg tgcacacgtc
    20641 tccatggtat gatcggttct agtcattata tctgctattg tctgattgga agatgtctat
    20701 gattgtctgg cgttgtcttt cttgtccctt gtctcgaccg tctgatcatc agttgtgggt
    20761 ttggcatccc aggtgggtat gagtgtcgct gcactcaatt tccatcggat gctccgatag
    20821 actttatcaa acgactcaca ggtggcgaat gaacctataa ggcagtgtgg ttcatatgga
    20881 gtactatgca gataccagcc tagtgcatag tcgtctcatg ataatgctta gtgaagtttc
    20941 gaaaagcagg caggtgcgtt atatcttgac cgagtaaagg tcttggtggg tttgtggcta
    21001 cggtgtatgt tccgacagat tatatatagt catgactaat ggttattatg ttaatggcaa
    21061 agtacaatca cgatcattac agggaattta ctcccgcttg agaaattgga atatcttaaa
    21121 cactgtaaat ctagctcttc caataaatct ggccctcaaa gagccgacgt gcagtacgga
    21181 agacagttgc cgcggtaagc tgatcgttct cgaattgagc cccaacaagc aaattcccac
    21241 ttgcatgacc gatcgtaaga ccagcatcac tgacgcgatc ttggttggtt gcatcttcaa
    21301 cagtactacc
//
