LOCUS       KZ851908.1             47548 bp    DNA     linear   PLN 20-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   KZ851908
VERSION     KZ851908.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 07:38:58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 718131
            Orig. end    :: 765679
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..47548
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[745627:>745679](-),
                     [744725:745572](-), [<738131:744660](-)}"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(join(<20001..26529,26595..27441,27497..>27548))
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..47548
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..47548
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T1PKS"
                     /region_number="3"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     mRNA            join(499..617,674..2475)
                     /locus_tag="M747DRAFT_294474"
                     /product="hypothetical protein"
     gene            499..2475
                     /locus_tag="M747DRAFT_294474"
     CDS             join(528..617,674..2365)
                     /codon_start=1
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR036864"
                     /db_xref="PFAM:PF00172"
                     /locus_tag="M747DRAFT_294474"
                     /note="EggNog:ENOG41; GO_component: GO:0005634 - nucleus
                     [Evidence IEA]; GO_function: GO:0000981 - DNA-binding
                     transcription factor activity, RNA polymerase II-specific
                     [Evidence IEA]; GO_function: GO:0008270 - zinc ion binding
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     transcription, DNA-templated [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_294474-T1"
                     /transl_table=1
                     /translation="MYLPVRPRPKKTDIIRSRNGCKSCRQRRTKCDEKQPTCGTCARLG
                     KTCERFSEDLQFRVVTSSDPRMPKRLRGKDRSHTRLGLSHVEPEGVSCGSMDLIRSLQH
                     TERDVFYLTYWEDQCLPTLHPILRFFTQSAAANVMLKNTMLALSACNLSRLNPEVRMRS
                     ESFHMGKFRPNLIHQTRSQLYYSAAISRLVNSDQLHDQRVAITVLAVIVILSYMESSMS
                     NFTAFYCHTDGLFRFLTNLNDYAQDETVRGLLTTWMQSRLSVWWMRSYFSSVKLQRLLP
                     SIPLPRILQGQPKSLHERRVEIMSIMCDSHYLSNSCILRHWDCEQSTETVIPEPSDAPG
                     TDALHFHVLLAHQVQRLDRWIQHLSPAEQPLMDSASTGDITTPLRFTSHDAALNYAYYL
                     TSCILQCQTIFCTLPPTCPTIATREGQTADPYVGLLLRIAKASPPAHHLKQNIYTIGFT
                     NLLLTALLRTTSVSLAIEIENFVQSLADTLPTEEGGFPIYQALAVIKLINVRKMAGKDV
                     VAVSQPVDDHGGEPKFQSYNSQAIRDLFFHGKERTGGALFKERVVIGRAGKLNGGEWRW
                     GRGRRRPVIYVSRFDGF"
     mRNA            complement(2573..3630)
                     /locus_tag="M747DRAFT_348632"
                     /product="pyridoxal phosphate-dependent enzyme, beta
                     subunit"
     gene            complement(2573..3630)
                     /locus_tag="M747DRAFT_348632"
     CDS             complement(2586..3542)
                     /codon_start=1
                     /db_xref="InterPro:IPR001926"
                     /db_xref="InterPro:IPR036052"
                     /db_xref="PFAM:PF00291"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081:cysteine synthase (Score: 262.9; E-value: 5e-80)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_348632"
                     /note="EggNog:ENOG41"
                     /product="pyridoxal phosphate-dependent enzyme, beta
                     subunit"
                     /protein_id="ncbi_M747DRAFT_348632-T1"
                     /transl_table=1
                     /translation="MSLIPSVDSALDAIGNTPCVQLTRVVPQDCARVFIKLESLNPTGS
                     YKDRMALSVIEEAERRNDLRPGMTVVEATGGSTGSSLAFVCAVKGYTFRVVSSDAFAKE
                     KLNTMTAFGAHLDIVPSENGKITPQLIPSMRERARRIATEDKDPSSYYYADQFSNPDVF
                     PGYETLGREILAQVGEPIDAFCGAVGGAGMVMGVGKTLKQSWPACHVAVLEPASAPALT
                     KGHGGEHSVEGIGIGFPPPLLNKDWYDEARAIDEREGRSMCRRLAREEGLLVGTSSGLN
                     VVAAIQLAKELGPGKTVVTVGCDTGLKYVRGNLYTDS"
     mRNA            complement(5877..7495)
                     /locus_tag="M747DRAFT_294476"
                     /product="MFS general substrate transporter"
     gene            complement(5877..7495)
                     /locus_tag="M747DRAFT_294476"
     CDS             complement(5888..7207)
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 97.3; E-value: 1.3e-29)"
                     /gene_kind="transport"
                     /locus_tag="M747DRAFT_294476"
                     /note="EggNog:ENOG41; GO_component: GO:0005887 - integral
                     component of plasma membrane [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="MFS general substrate transporter"
                     /protein_id="ncbi_M747DRAFT_294476-T1"
                     /transl_table=1
                     /translation="MFNVVQSAAAENYGAQDTNRKTASIHPRRNTIWRLASACLMNFGN
                     GMNDSAPGALIPYIEDDYGIGYAIISLIFIANAVGFVLAAPLTHTIQARIGHAKSYALS
                     MSLVTAGYVAIVCHPPFPVVVTAFLLLGFGMALSIALNNVFCANLNSYATALGFFSGAY
                     GIGGVISPLLATAMVSHGIRWTYFYFITLVISTLNMLLAAVVFRNYKDEGAASRAPTQQ
                     TSPSLASQTAQPNENDSHNSHTRLQTLKRAIRNLTTILGSLFIFAYQGAEVSISGWIVS
                     FLINYRGGDSRRVGYVSAGFWAGITLGRFLLVYPANRIGEELAVGLLVVGAIAFQLMTW
                     LIPNIVGEAVAVAVVGLLLGPMYPCSTAVFAKLLPRSIQLTSMSFITALGSSGGAVFPF
                     LTGILSQEVGTIVLHPICLALYAAMVVCWCFLPAISKRSE"
     tRNA            complement(9631..9704)
                     /locus_tag="M747DRAFT_t79"
                     /product="tRNA-Ile"
     gene            complement(9631..9704)
                     /locus_tag="M747DRAFT_t79"
     mRNA            join(<10398..10704,10760..10917,10971..11966,12020..12375,
                     13535..13620,13749..14030,14112..14229,14291..>14453)
                     /locus_tag="M747DRAFT_313904"
                     /product="arylsulfatase"
     gene            <10398..>14453
                     /locus_tag="M747DRAFT_313904"
     CDS             join(<10398..10704,10760..10917,10971..11966,12020..12375,
                     13535..13620,13749..14030,14112..14229,14291..>14453)
                     /codon_start=1
                     /db_xref="InterPro:IPR000917"
                     /db_xref="InterPro:IPR008901"
                     /db_xref="InterPro:IPR017850"
                     /db_xref="InterPro:IPR024607"
                     /db_xref="PFAM:PF00884"
                     /db_xref="PFAM:PF05875"
                     /locus_tag="M747DRAFT_313904"
                     /note="SECRETED:SignalP(1-19); EggNog:ENOG41; GO_component:
                     GO:0016021 - integral component of membrane [Evidence IEA];
                     GO_function: GO:0008484 - sulfuric ester hydrolase activity
                     [Evidence IEA]; GO_function: GO:0003824 - catalytic
                     activity [Evidence IEA]; GO_function: GO:0016811 -
                     hydrolase activity, acting on carbon-nitrogen (but not
                     peptide) bonds, in linear amides [Evidence IEA];
                     GO_process: GO:0006672 - ceramide metabolic process
                     [Evidence IEA]"
                     /product="arylsulfatase"
                     /protein_id="ncbi_M747DRAFT_313904-T1"
                     /transl_table=1
                     /translation="MRSLVYLLALAGLTTKSLGQQKQQQPLSATAKPNVVFILTDDQDA
                     HLASLDYMPYVQKHLLDKGTHYRSHYCTTSVCCPSRVTLWTGKLAHNTNVTDVNPPHGG
                     YPKFISQGLNDNYLPVWLQEAGYNTYYTGKLFNVHTVDNYNAPFPAGFTGNDFLLDPFT
                     YDYLNSTFQRDHEIPQSYEGEYSTDVLAQKAYRLLNEAVTAQKPFFLTVAPIAPHCNVF
                     MNGTGLDANPKFSFSAPIPAKRHEHLFPDVKVPRTPSFNPEIPSGANWIKTLKRQNDTN
                     VDYNDHFYRQRLRTLQAVDELVDGLFTRLKEYNILDNTYIVYSSDNGYHIGQHRLQPGK
                     SCGYEEDINVPLIIRGPDIAQNVSTDIVTTHTDLAPTFLELLGIPLREDFDGNPISLTR
                     SQIERAQEERQEHVTVEYWRYAAGEGIYDCAYSTPTPHSLTMAELILIMKVDLSAYNNT
                     YKALRIKGIGYNLYYSVWCNNEHELYDMTTDPHQLHNLLSAIEQPSATSHTILNVDLSK
                     VVQRLDSLLLVLKSCKAQVCVKPWDALHPRGEVMTLKDALDVHYDHFYEVEQTTRVQFN
                     ECARGYFLDAEGPQFDSGTDYEVLRDGLPCSIWHLRSLAAPQQTPNRATLNHILRIDWP
                     DELSMHLLTTPLLYRILSFQATPQYTKTVGIILSVLFTIVMVVHMVMDEFLLHAVTFGA
                     AVCLITTRTLKIIPREIPDVEARKRIQSVALFGCASFIFGYLVWLIDEFVCQSLIVARH
                     AVGLPVAFLLELHGWWHVFTAIGGYIAVAVIDLITSGEVQRDSVAQLAWPLPTVARLLG
                     PAAGETKRE"
     mRNA            join(<16226..16549,16620..16722,16792..16860,16920..17522,
                     17590..>18011)
                     /locus_tag="M747DRAFT_233486"
                     /product="cytochrome P450 monooxygenase"
     gene            <16226..>18011
                     /locus_tag="M747DRAFT_233486"
     CDS             join(<16226..16549,16620..16722,16792..16860,16920..17522,
                     17590..>18011)
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002403"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="InterPro:IPR036396"
                     /db_xref="PFAM:PF00067"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 116; E-value: 3.5e-35)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_233486"
                     /note="EggNog:ENOG41; GO_function: GO:0005506 - iron ion
                     binding [Evidence IEA]; GO_function: GO:0020037 - heme
                     binding [Evidence IEA]; GO_function: GO:0016705 -
                     oxidoreductase activity, acting on paired donors, with
                     incorporation or reduction of molecular oxygen [Evidence
                     IEA]; GO_function: GO:0004497 - monooxygenase activity
                     [Evidence IEA]; GO_process: GO:0055114 -
                     oxidation-reduction process [Evidence IEA]"
                     /product="cytochrome P450 monooxygenase"
                     /protein_id="ncbi_M747DRAFT_233486-T1"
                     /sec_met_domain="p450 (E-value: 7.7e-37, bitscore: 121.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MENMLGYTSMPVPVLVSLALGLAFLLLQSFRYKDPALNPKKPFEL
                     TSTRVKQEYFSNARRLLWDWFTTHSNTPVLLHTDTGKVTILPPSMANEIRNDDRLSFSR
                     WTFEAFHGNLPGFDGFREGSQDSGIVQAVIGNDLTKYLNKVTEPLANETSVAVRELLTD
                     NEEWHTIQLRTVMVALISRISSRVFLGEKLCRNEEWLRVTQDYTTDGFLAAEELRMWPA
                     AIRPIVHWFLPRCRKLRAQVKVARKVMGPILEERRQFKKHLHAEGKQSQGFDDAIEWFE
                     KAAKGRPYDPVSAQLILSVAAIHTTSDLTSQTMTHLVQNPEILEPLRKEIVDTLQQHGW
                     KKTALYNMKLLDSVIRESQRLKPINNASMRRVALKEVKLSDGTVIPKNGMLAVSAHKLW
                     DDDTYENAAAWDGYRFYKMREDPERQTKAQLVTTAPENLAFGHGKHACPGRFFAANEVK
                     IALIYLLLRYDWKLLEGTVPKIRYGGFSMAVDPSLKMEVKRRREEMGI"
     mRNA            join(18343..18503,18570..19985)
                     /locus_tag="M747DRAFT_322226"
                     /product="hypothetical protein"
     gene            18343..19985
                     /locus_tag="M747DRAFT_322226"
     CDS             join(18405..18503,18570..19871)
                     /codon_start=1
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR036864"
                     /db_xref="PFAM:PF00172"
                     /locus_tag="M747DRAFT_322226"
                     /note="EggNog:ENOG41; GO_component: GO:0005634 - nucleus
                     [Evidence IEA]; GO_function: GO:0000981 - DNA-binding
                     transcription factor activity, RNA polymerase II-specific
                     [Evidence IEA]; GO_function: GO:0008270 - zinc ion binding
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     transcription, DNA-templated [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_322226-T1"
                     /transl_table=1
                     /translation="MGASLTPYTQTLSRKSHRKSRLGCKNCKRRRIKCDEIKPHCTNCL
                     RHSIECDYSFKPQTNSSSSPQSQQSDSVSPPSQGPSTDSYTFYTSSSVNFQPPKRGHGT
                     PLTSGPDTTQPSPPSNNDLAKRPFQYTALDMLLFHHFSTSPELTGAQPKARQQLSQIAF
                     SHHYVMHILLAFSGFHLVRRSDDQQWSQSMGFTEAEIYTEAERHFNVAIRDVSATLPHL
                     DRDNSPAMYASAIFIFISSLARGPQPGEYLAFRSDGTPGHLSLFLGVRSVFELCSGDMP
                     TSVFSIHGEGDDSSSRTTPQTEHENSHIASQNKTKLEDYPHHLETYRALLTTTIPIDDP
                     RLSIYLQTLDRLGHSLDAIMGPDPQGTMGMALFPLVFAWLYQLPDAVVGDLQRREPVAL
                     ILFAFFLYPLDRLDHVWFICGWPRHILEGIQWHLDGRYRGYIQWAVDHVGGGRLSEGLG
                     VGMEVVSR"
     mRNA            complement(join(<20001..26529,26595..27441,27497..>27548))
                     /locus_tag="M747DRAFT_369040"
                     /product="polyketide synthase"
     gene            complement(<20001..>27548)
                     /locus_tag="M747DRAFT_369040"
     CDS             complement(join(<20001..26529,26595..27441,27497..>27548))
                     /NRPS_PKS="Domain: PKS_KS (11-437). E-value: 2.6e-148.
                     Score: 486.1. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_369040_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (587-904). E-value: 8.8e-83.
                     Score: 269.7. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_369040_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (984-1161). E-value: 5.8e-33.
                     Score: 106.2. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_369040_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1728-2037). E-value: 9.5e-82.
                     Score: 266.2. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_369040_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (2064-2244). E-value: 8.4e-44.
                     Score: 141.3. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_369040_PKS_KR.1"
                     /NRPS_PKS="type: Type I Iterative PKS"
                     /codon_start=1
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR018201"
                     /db_xref="InterPro:IPR020801"
                     /db_xref="InterPro:IPR020806"
                     /db_xref="InterPro:IPR020807"
                     /db_xref="InterPro:IPR020841"
                     /db_xref="InterPro:IPR020843"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="InterPro:IPR032821"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="InterPro:IPR036736"
                     /db_xref="InterPro:IPR042104"
                     /db_xref="PFAM:PF00107"
                     /db_xref="PFAM:PF00109"
                     /db_xref="PFAM:PF00550"
                     /db_xref="PFAM:PF00698"
                     /db_xref="PFAM:PF02801"
                     /db_xref="PFAM:PF08659"
                     /db_xref="PFAM:PF14765"
                     /db_xref="PFAM:PF16197"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 215.4; E-value:
                     2.4e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="M747DRAFT_369040"
                     /note="EggNog:ENOG41; GO_function: GO:0031177 -
                     phosphopantetheine binding [Evidence IEA]; GO_function:
                     GO:0016491 - oxidoreductase activity [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]; GO_function: GO:0016740 - transferase activity
                     [Evidence IEA]; GO_process: GO:0055114 -
                     oxidation-reduction process [Evidence IEA]"
                     /product="polyketide synthase"
                     /protein_id="ncbi_M747DRAFT_369040-T1"
                     /sec_met_domain="PP-binding (E-value: 2.6e-07, bitscore:
                     25.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5.7e-82, bitscore: 269.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 1.8e-150, bitscore:
                     495.7, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 4.9e-40, bitscore:
                     131.7, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTPPRSNECEPIAIVGMGCRLPGGVQDIPALWEFLRDQKDAHGEF
                     AAPRFSAEGFYHANSDRPGTAVASSGFLLKEDPRLFDPSFFGITDVEAETMDASQRKLL
                     EVTYEAFENAGETWDSVSGSRIGVFVGDISFDNYVSQTRDWDYSGKYSATGAFPNMLAN
                     RIHYVFNLKGPSLLINSACTSAMYALHLAITSMRNGDCDSAIVAGSNWVMDPNCHIAMG
                     KLGALSPSSRSHTFDASADGYARGEGFAALYLKTVSLATQDASPIRALIRGSAVNANGR
                     TSGITNPSGPAQETVIREAYKNAGDLDPSETTLLECHGTGTRVGDPIEVTAAGNVFGPS
                     RSTVHEDRLVVGSVKTNVGHLEGACALPGILKVVASLEAGEIPATLGFQTPNPRIDFDQ
                     AKARVVNKTEPWPKDRLKRASVTSAGFGGTNGHCIIDHVHNVIPEYVKPGVIYEQVEQS
                     NGTNGHAVNGTNGTNGTHGTKPEALSQLHRPILHSPTLVRRADATTRQMVVLPFSAHNQ
                     SSLIANMEALQRSIPHHSLADVAYTLAAKRSRFSQRAFSIVDKDQVTQVGSVTDNGPKV
                     FASPQRVNVGFVFTGQGAQWPAMGAELFEYAVFRDTIAYLDTVLAVLPQPAPWKLVDIL
                     CGNCDKDLIQKPAVSQTVCTALQMGLVDLLASWSVRPAGVVGHSSGEMAAAYAAGRITA
                     AEAITIAYYRGYMVSFNQKKGAMLAVGLGADQGAEYVRQAGMEGRVKVAAINSPASITM
                     SGDADAIEQLSVQLTQEAIFNRQLRTGGLAYHSHHMLSFGHDYAQAVDDGLQRLASLGI
                     NDTTSRYSNIPWASSVVPQKSSTMPREEVTASYWKANLESPVRFTDAVSKLLDMDDLRI
                     GATVEIGPHPALKGPLGQIVKGLGRTIPHVASVERGQDSRRSLLGLAGTLFALNADVDL
                     VAVNAVDESHGAGKRTLIHGCMAIDLPPYRYTYGPIKYHESRLSKEYRLRRWPRHDLLG
                     ARVPGTTRLRPQWRNILRLKDLPWLNDHRVPPHVLHPGAAHIVMAMLAAEQAYAEFPDA
                     LPVAGLTLRNVSIKKTLVVPQDDKGIEIVLSMELEDGATAASPGWASFSIASVVNDSEQ
                     WTEHCSGLVKVDVVAFNAPAAIDTTTMDGRAVDAQAWYTRFADMGLQFGPSFQGYSDIW
                     ADPFSNVALAKLSLNTTAGLFPGGESRYPIHPASLDLVIRLGLMACNGGQAETASVQLP
                     IHFDQMRFKLGCLQGRDWITGVSRGELRGLRGAYAQLQLLDDSGEAILDVDNMRFTSLN
                     NEQQSSAQDFSGQAYSSPFARLVWRPDSRTLSRDQWNKLLASVDGTTTFSRLSYLIDLV
                     GHANPDLRILQLSAGSDDRNAGQAVLKSLVGHNGIKRYREYVATDTSAERLDSFRETVS
                     AFRDVRYSVLDISQDPSEQEFQIGTYDMILWSNVEHGPATEQALANAKKLLHPGGHLVL
                     VDRMNSSELAWDQCLRRVGFDSGYKLVCRETDLHSTIILSTLPDPVPTTKSGNPVVHLL
                     HGSQGTSALLHHLARAMEQHGLSIRISPMDQAINVLAPNSRVVAFLDGENLLFAADQRR
                     LGLFQHLAANTASMVWVTSCGLVKGRNPDGAFVSGLLRTLGTENPAGQFLSVDVDAEDF
                     QVPGLEMDELVRCLVEQELLLQPTLDDKGPPEVNRDLVWQDGCMWTSRIVPDGQLQGYA
                     EVAPTRQEVDVSSRPLSSLGPVRAAFETPGILTSLYFRPYTELLQPLPRDYIDVKVDAV
                     GLNWKDLGLCSGRFDANNLSNEYCGVVTQVGADVTRLSIGDRVYGMGKGHFGTHTRVPA
                     GLAQKLAADVNAIEAATMPLVYMTAVYAFEHVTRLKPGHKVLIQSATGGLGLAAIQLAR
                     SKGATIYATAGTADKVRFLTDHMGVPASQIFSSRDLASLNRATQQHGGFDVILSTAQGD
                     MLYESVKALAPLGHLVDVGRLDVTSSQTMGLELFQKSAGFTSFDLGLVVERDSVLGAEL
                     MQSVDAHFRAGHIGPIKPYSVADIGYLDQTLLQFSQGTHIGKRVITYQDPSTLLRTLPT
                     SSATPARFDPAARYILVGGLTGLGRSIVRWMSSRGARDMEVWSRRGASNLAPEAQRMIT
                     ELAAQGIRVQPVACDVTNRDAVLHTMRSAHVDPTRPVRGVFHFAVSYQDISFDKMTEAQ
                     FNQGMAAKVFGVKHLHDATTSIPLDFFAMTSSLGTVYAFPTQSTYLAANNYLDYFARYR
                     RRLGLPATTVALGFINDLGPLTNDPVTVNLFVRAKGQTMTGAQVVRMLEPAFVNEQPNA
                     LWLGHTDDPLSASHIVTGIDPAVLAKMARSSAASLASSTIPRWYHDSRVSLMLRALEDA
                     SSATSSLSSSDIHASDASPTAQLRRQFDHSVATLRAGGKDSKEDAWTETIKFVTEAIQA
                     TVAGMLFVDVGSVNPNKTVAEHGIDSLLAAEFRNWFQGAFGRGVSMLELMDARMSLALL
                     ARSVVEGAVGV"
     aSDomain        complement(20697..21236)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_369040_PKS_KR.1"
                     /evalue="8.40E-44"
                     /label="M747DRAFT_369040_PKS_KR.1"
                     /locus_tag="M747DRAFT_369040"
                     /score="141.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="YILVGGLTGLGRSIVRWMSSRGARDMEVWSRRGASNLAPEAQRMI
                     TELAAQGIRVQPVACDVTNRDAVLHTMRSAHVDPTRPVRGVFHFAVSYQDISFDKMTEA
                     QFNQGMAAKVFGVKHLHDATTSIPLDFFAMTSSLGTVYAFPTQSTYLAANNYLDYFARY
                     RRRLGLPATTVALGFIND"
     CDS_motif       complement(20742..20852)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_369040_0010"
                     /evalue="5.60E-13"
                     /label="PKSI-KR_m4"
                     /locus_tag="M747DRAFT_369040"
                     /score="41.4"
                     /tool="antismash"
                     /translation="LDFFAMTSSLGTVYAFPTQSTYLAANNYLDYFARYRRR"
     CDS_motif       complement(21165..21236)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_369040_0009"
                     /evalue="7.30E-10"
                     /label="PKSI-KR_m1"
                     /locus_tag="M747DRAFT_369040"
                     /score="31.4"
                     /tool="antismash"
                     /translation="YILVGGLTGLGRSIVRWMSSRGARD"
     aSDomain        complement(21318..22244)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_369040_PKS_ER.1"
                     /evalue="9.50E-82"
                     /label="M747DRAFT_369040_PKS_ER.1"
                     /locus_tag="M747DRAFT_369040"
                     /score="266.2"
                     /tool="antismash"
                     /translation="LTSLYFRPYTELLQPLPRDYIDVKVDAVGLNWKDLGLCSGRFDAN
                     NLSNEYCGVVTQVGADVTRLSIGDRVYGMGKGHFGTHTRVPAGLAQKLAADVNAIEAAT
                     MPLVYMTAVYAFEHVTRLKPGHKVLIQSATGGLGLAAIQLARSKGATIYATAGTADKVR
                     FLTDHMGVPASQIFSSRDLASLNRATQQHGGFDVILSTAQGDMLYESVKALAPLGHLVD
                     VGRLDVTSSQTMGLELFQKSAGFTSFDLGLVVERDSVLGAELMQSVDAHFRAGHIGPIK
                     PYSVADIGYLDQTLLQFSQGTHIGKRVIT"
     CDS_motif       complement(21750..21800)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_369040_0008"
                     /evalue="7.10E-05"
                     /label="PKSI-ER_m6"
                     /locus_tag="M747DRAFT_369040"
                     /score="15.5"
                     /tool="antismash"
                     /translation="GATIYATAGTADKVRFLT"
     CDS_motif       complement(21810..21872)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_369040_0007"
                     /evalue="1.00E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="M747DRAFT_369040"
                     /score="27.5"
                     /tool="antismash"
                     /translation="GHKVLIQSATGGLGLAAIQLAR"
     CDS_motif       complement(21897..21941)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_369040_0006"
                     /evalue="1.80E-03"
                     /label="PKSI-ER_m4"
                     /locus_tag="M747DRAFT_369040"
                     /score="11.8"
                     /tool="antismash"
                     /translation="AATMPLVYMTAVYAFE"
     aSDomain        complement(23946..24476)
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_369040_PKS_DH.1"
                     /evalue="5.80E-33"
                     /label="M747DRAFT_369040_PKS_DH.1"
                     /locus_tag="M747DRAFT_369040"
                     /score="106.2"
                     /tool="antismash"
                     /translation="HDLLGARVPGTTRLRPQWRNILRLKDLPWLNDHRVPPHVLHPGAA
                     HIVMAMLAAEQAYAEFPDALPVAGLTLRNVSIKKTLVVPQDDKGIEIVLSMELEDGATA
                     ASPGWASFSIASVVNDSEQWTEHCSGLVKVDVVAFNAPAAIDTTTMDGRAVDAQAWYTR
                     FADMGLQFGPSFQGY"
     CDS_motif       complement(24315..24392)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_369040_0005"
                     /evalue="4.60E-06"
                     /label="PKSI-DH_m2"
                     /locus_tag="M747DRAFT_369040"
                     /score="19.2"
                     /tool="antismash"
                     /translation="WLNDHRVPPHVLHPGAAHIVMAMLAAE"
     aSDomain        complement(24717..25667)
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_369040_PKS_AT.1"
                     /evalue="8.80E-83"
                     /label="M747DRAFT_369040_PKS_AT.1"
                     /locus_tag="M747DRAFT_369040"
                     /score="269.7"
                     /specificity="consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mxmal"
                     /tool="antismash"
                     /translation="VFTGQGAQWPAMGAELFEYAVFRDTIAYLDTVLAVLPQPAPWKLV
                     DILCGNCDKDLIQKPAVSQTVCTALQMGLVDLLASWSVRPAGVVGHSSGEMAAAYAAGR
                     ITAAEAITIAYYRGYMVSFNQKKGAMLAVGLGADQGAEYVRQAGMEGRVKVAAINSPAS
                     ITMSGDADAIEQLSVQLTQEAIFNRQLRTGGLAYHSHHMLSFGHDYAQAVDDGLQRLAS
                     LGINDTTSRYSNIPWASSVVPQKSSTMPREEVTASYWKANLESPVRFTDAVSKLLDMDD
                     LRIGATVEIGPHPALKGPLGQIVKGLGRTIPHVASVE"
     CDS_motif       complement(25326..25421)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_369040_0004"
                     /evalue="4.20E-08"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="M747DRAFT_369040"
                     /score="25.8"
                     /tool="antismash"
                     /translation="VRPAGVVGHSSGEMAAAYAAGRITAAEAITIAY"
     CDS_motif       complement(25620..25670)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_369040_0003"
                     /evalue="1.60E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="M747DRAFT_369040"
                     /score="17.3"
                     /tool="antismash"
                     /translation="FVFTGQGAQWPAMGAELF"
     aSDomain        complement(join(26118..26529,26595..27441,27497..27515))
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_369040_PKS_KS.1"
                     /evalue="2.60E-148"
                     /label="M747DRAFT_369040_PKS_KS.1"
                     /locus_tag="M747DRAFT_369040"
                     /score="486.1"
                     /tool="antismash"
                     /translation="IAIVGMGCRLPGGVQDIPALWEFLRDQKDAHGEFAAPRFSAEGFY
                     HANSDRPGTAVASSGFLLKEDPRLFDPSFFGITDVEAETMDASQRKLLEVTYEAFENAG
                     ETWDSVSGSRIGVFVGDISFDNYVSQTRDWDYSGKYSATGAFPNMLANRIHYVFNLKGP
                     SLLINSACTSAMYALHLAITSMRNGDCDSAIVAGSNWVMDPNCHIAMGKLGALSPSSRS
                     HTFDASADGYARGEGFAALYLKTVSLATQDASPIRALIRGSAVNANGRTSGITNPSGPA
                     QETVIREAYKNAGDLDPSETTLLECHGTGTRVGDPIEVTAAGNVFGPSRSTVHEDRLVV
                     GSVKTNVGHLEGACALPGILKVVASLEAGEIPATLGFQTPNPRIDFDQAKARVVNKTEP
                     WPKDRLKRASVTSAGFGGTNGHCIIDHV"
     CDS_motif       complement(26442..26486)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_369040_0002"
                     /evalue="6.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="M747DRAFT_369040"
                     /score="12.0"
                     /tool="antismash"
                     /translation="LECHGTGTRVGDPIEV"
     CDS_motif       complement(26750..26788)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_369040_0001"
                     /evalue="2.80E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="M747DRAFT_369040"
                     /score="13.9"
                     /tool="antismash"
                     /translation="FDASADGYARGEGF"
     mRNA            join(28885..29215,29290..29571,29637..29785,29845..30318,
                     30377..31602)
                     /locus_tag="M747DRAFT_277323"
                     /product="hypothetical protein"
     gene            28885..31602
                     /locus_tag="M747DRAFT_277323"
     CDS             join(29135..29215,29290..29571,29637..29785,29845..30318,
                     30377..31400)
                     /codon_start=1
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR007219"
                     /db_xref="InterPro:IPR036864"
                     /db_xref="PFAM:PF04082"
                     /locus_tag="M747DRAFT_277323"
                     /note="EggNog:ENOG41; GO_component: GO:0005634 - nucleus
                     [Evidence IEA]; GO_function: GO:0008270 - zinc ion binding
                     [Evidence IEA]; GO_function: GO:0000981 - DNA-binding
                     transcription factor activity, RNA polymerase II-specific
                     [Evidence IEA]; GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     transcription, DNA-templated [Evidence IEA]; GO_process:
                     GO:0006351 - transcription, DNA-templated [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_277323-T1"
                     /transl_table=1
                     /translation="MGGAAMHPTGRKRRVTTCVPCYTRKQRCNRQYPCNHCTRRRRPEE
                     CVYQSIITGDPSNTFLLEPARDPEPQEPPNVQLPNGSSKASPAEAQNSASNSHSALAKS
                     FGYFEHSDSNTMALLKKWDLDSEGDTDQSTQGLSTAVLETVKQVLEKIPPRPILDFLMQ
                     YFVDELNWMKQIIHPPSFLTQYQHWWTKEWPLSVDDIEFAALVLRIGAYSAQFLPSPTH
                     TLDRIRGQSLSDIRDTCSHLGGELARACLSLNWKGSLVRVQHILFAAFRSSCEGRTDKF
                     WEGIASACSAAQKAGIHTVAPVPGEDSSQVLEKEMRRRTLCGLYVLDSHLARQLDRVPF
                     LPDNLVLETLPRLRLAPFIGDLAASADAPEDFTERLMQVRLGRFWRSFGSRRNLPYDPT
                     HGEQRYERFCAEYIPTLPPAYALNPDRRWDGQLPKLPMQRQLLYIAIFDSVCWNFRPLL
                     LLKPGQVTSLPPYKQVLLQSQKQKLALAALEELDAVTALHIMFGGSHTRFSAIIFNTFE
                     AAVVLLILCTQKDFPFDQGEDHPDILGLRVATLTRPRAMRAVEKALGRLQMLAEVSEMA
                     ASGAQVVTQLFAKAARMEHSLEPYTPNESSRSSSSPAILSNFLNLEDGSGLWMSSEDPT
                     LMPDMLSTIAHGDSYSMLQFPSLDLTSWNGNFHS"
     mRNA            join(<32133..33161,33225..33898,34014..>34032)
                     /locus_tag="M747DRAFT_330183"
                     /product="cytochrome P450"
     gene            <32133..>34032
                     /locus_tag="M747DRAFT_330183"
     CDS             join(<32133..33161,33225..33898,34014..>34032)
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002403"
                     /db_xref="InterPro:IPR036396"
                     /db_xref="PFAM:PF00067"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 125; E-value: 6.4e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_330183"
                     /note="EggNog:ENOG41; GO_function: GO:0020037 - heme
                     binding [Evidence IEA]; GO_function: GO:0005506 - iron ion
                     binding [Evidence IEA]; GO_function: GO:0016705 -
                     oxidoreductase activity, acting on paired donors, with
                     incorporation or reduction of molecular oxygen [Evidence
                     IEA]; GO_function: GO:0004497 - monooxygenase activity
                     [Evidence IEA]; GO_process: GO:0055114 -
                     oxidation-reduction process [Evidence IEA]"
                     /product="cytochrome P450"
                     /protein_id="ncbi_M747DRAFT_330183-T1"
                     /sec_met_domain="p450 (E-value: 1.6e-32, bitscore: 107.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MAPSYIASFVELFHGYPAVFSITICLVGLYVLYRWLLPSPLPGIP
                     YNKQAATSILGDVPALRGDPAGLAKWCSKQLEEHGSPICQALMGPLSKPVVLVADVGQT
                     RELLMGRSDFDRSSYIIDRFPLFGEFHLNMKTGDSWRTSRSWLKDLLAPHYLHQTVGPI
                     IHSSVLNLIHLWESKARVANGRPFSMLADLKTLALDVIVRFHFGQDFQDSALRRQIEFV
                     EQLDNSQLGVGKHTDVIFPQASLHPFQQGLTDVGDRMAAIYTTKWPPSIVSWWARYMSP
                     YYRKFFVGKDRFIRKHINLALQRFGNDEEAKTGIDYMVYREQKSSRKADRQPMYGKQIM
                     IDEAYGNLIAGQHTTSAALVWILKLLAEHPAVQTRLRDELQTVCAAAVQEGRLPTAAEI
                     IQFRLPYLDAVLEETLRLRAAMLVPRDATRDTELLGRRIPKGTVVLLVCQGPDYSSSPS
                     SLYWSDVKTTRKYPGGGNPDLEAFDPERWLVQNERGELEFDGSSYPQLAFGLGIRACWG
                     RRLAQLEMRIMTVMMTWKFDFLDVPEALAGHEATYDISYRAKKGYLRLRSRNDERK"
     mRNA            <34732..>36396
                     /locus_tag="M747DRAFT_322230"
                     /product="MFS general substrate transporter"
     gene            <34732..>36396
                     /locus_tag="M747DRAFT_322230"
     CDS             <34732..>36396
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 270.3; E-value:
                     3.8e-82)"
                     /gene_kind="transport"
                     /locus_tag="M747DRAFT_322230"
                     /note="EggNog:ENOG41; GO_component: GO:0005887 - integral
                     component of plasma membrane [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="MFS general substrate transporter"
                     /protein_id="ncbi_M747DRAFT_322230-T1"
                     /transl_table=1
                     /translation="MEAAAHSLPSSQESDFAVNNHLPHREESDEKGHDADASATDDDVR
                     KITGFRWFLICAALYLSALMYGLDTTIAADVQGAVIERFGDVSQLAWIGAGFPLGSVAV
                     ILPYGFLYTVMNMKWLYIAGIVLFQGGSALCGGAPNMNALIVGRVIAGAGGTGIYLGGL
                     NHFSAMTTRNERGTYLTGTGFVWGVGAILGPVVGGGFSDSSATWRWGFYLNLVIGAITA
                     PVYLFYLPAIHPGAGQSLRKRLTRLDYLGFVLSAAMWVTFALGFISAGGIWAWDSGATI
                     ALIVLFGVLFILYALQQYLCIFTTPQTRSFPGHLLRSRTQILLYITTTCANTAMFFTTF
                     YIPIYFQFTRNDSSLMAAVRLLPYLLVTITINLAIGWLLPKAKYYMPLCLISGILLTLA
                     SALFVGYLSPSTPAGQIYGFTILMAVGTGMTMQLGYAVASLKVPPEDIFSAINLQNVAQ
                     IGATVICLVVASQVFQSTAVKNLKGVLDGRGYSEAEIRNAVAGVQSTLLKSLSGELRDR
                     AIKAITDAMARAFIIPLVAGAVGVVSSLGMRRERLFG"
     CDS             complement(join(<36690..36937,36970..37894,38059..38594,
                     38657..39653))
                     /codon_start=1
                     /db_xref="InterPro:IPR000845"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR035994"
                     /db_xref="PFAM:PF01048"
                     /locus_tag="M747DRAFT_322231"
                     /note="EggNog:ENOG41; GO_function: GO:0003824 - catalytic
                     activity [Evidence IEA]; GO_process: GO:0009116 -
                     nucleoside metabolic process [Evidence IEA]"
                     /product="purine and uridine phosphorylase"
                     /protein_id="ncbi_M747DRAFT_322231-T1"
                     /transl_table=1
                     /translation="MSGNDVPSYDEFAVGWICALPLEMTAAKAVLDEEYPSLHLPKQHH
                     NTYVLGRISGHKVVITCLPFGIYGTTSATAVVEQMLFTFRSIRFGLMVGIGGGVPSAVD
                     VRLGDVVVSKPTAGLPGVIQYDYGKTVASGRFEQTGTLNKPPIVLLSALSSLEADRLAG
                     GSDIGTYEKIIADSLRAAKDPSVFRYPGAEHDWLFDASYDHDPRFASCAECDPERRVRR
                     KPRRSCTPVVHYGNIASGNQVMKHGLTRDRIAQTTQGILCFEMEAAGIMDYLPCLVIRG
                     ICDYSDSHKKKEWQGFAALTAAAYAKLLLSKIPVHRSEASTLIQAPGSKNSSDSFDVRF
                     DTIEMPQAAISVGREAELAMITKSLLSDRFRGIVTLYGMGGIGKTELSIMYIMRHRQKY
                     SSVFWIDGSSLDKLYSSYTQAAMRIIHDHPGDQSLRKALKEGDQIQLVGSVNEWLSRPS
                     NNRWLLIYDGFDLPMVEGFDKAEIMKMRLPPSKQGHIIITMRSYDIGIGDQIQLDGLPL
                     AIVSAGAYLKQSVITCREYLKLYKESWLQLQQLSPQQSSLEQKSMHTTWKITLNQIMRQ
                     HRHAAVLLKQWIAFNSNDIWYGLFQSARPESASDPLVFDTAMAVLSRYGWVEPGPVAAG
                     NSQQGRGYSLQKCIHAWLQYEDCFVSDIDLLTQLAVLKISTYQLDLVTKFNFFSLELPD
                     RNRLLPHADRCLEIYLSSGKDKYNSLFDLKAQLRLADLYMIWSTRASPIYTCYLDFLCQ
                     PYEEKRNLAKSQDLYCLLMEKLDMQQDQSNREVQDMMSKVYHQRGLIMFRNQQFVMASK
                     MFRLSIHTDAVFERANFSYPTKWAYLLYFTSRGRLQEGRPAKYVAALRETNCVSSLIDI
                     SKDATVENLVAVGSWPRLFPGVLLVNSAYA"
     mRNA            complement(join(<36690..36937,36970..37894,38059..38594,
                     38657..39725))
                     /locus_tag="M747DRAFT_322231"
                     /product="purine and uridine phosphorylase"
     gene            complement(<36690..39725)
                     /locus_tag="M747DRAFT_322231"
     tRNA            40512..40585
                     /locus_tag="M747DRAFT_t75"
                     /product="tRNA-Val"
     gene            40512..40585
                     /locus_tag="M747DRAFT_t75"
     mRNA            complement(40808..42019)
                     /locus_tag="M747DRAFT_294480"
                     /product="beta-lactamase/transpeptidase-like protein"
     gene            complement(40808..42019)
                     /locus_tag="M747DRAFT_294480"
     CDS             complement(40849..41982)
                     /codon_start=1
                     /db_xref="InterPro:IPR001466"
                     /db_xref="InterPro:IPR012338"
                     /db_xref="PFAM:PF00144"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 114.2; E-value: 1.2e-34)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_294480"
                     /note="MEROPS:MER0011726; EggNog:ENOG41"
                     /product="beta-lactamase/transpeptidase-like protein"
                     /protein_id="ncbi_M747DRAFT_294480-T1"
                     /transl_table=1
                     /translation="MTTINGHCDPAFTGVRDLLQQLINNEEELGASICVNIDGQNVVDL
                     WGGHADPARTKPWEKDTLTVVWSVSKVITAIATNILIDRGLLDPNEKVSKYWPEFAANG
                     KENILVSQILSHTSGVSSWELPNTLDDIYDAKRGADKLARQAPWWTPGEHSGYHVTNQG
                     HLLGELVHRVTGKPLDEFIRDELASPLAADFQLGVPEKDWPRTADVSPPPPLSLDGVDP
                     QSVMFKSFASLPIPAEESMSPGFRKALIGATNGFSNARGIARIASVISLGGTVDGKQYL
                     SPETIDRMLEEQISGPDLVLMYHLRWGLGVGLPVPETFPWLPDGRIAFWTGWGGSVVVM
                     DLEKRMTIAYVMNKMGQGTLGSDRTAAYVRAVYDCLA"
     mRNA            complement(join(<43064..43802,43862..>44085))
                     /locus_tag="M747DRAFT_339903"
                     /product="hypothetical protein"
     gene            complement(<43064..>44085)
                     /locus_tag="M747DRAFT_339903"
     CDS             complement(join(<43064..43802,43862..>44085))
                     /codon_start=1
                     /locus_tag="M747DRAFT_339903"
                     /note="SECRETED:SignalP(1-19); EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_339903-T1"
                     /transl_table=1
                     /translation="MKLSTFLFSLLATSQVTLATPIPIVDVAELPSDTGLEIRSPNPAD
                     ELLAILEQRDTRVCEILNRTIRSIGTSKFTVVYIVMGSRLARQVCEYAGGSRCEEISYI
                     ISDGLLLAYVAAAHYSGAIPEGLPGKRDVDVSQDYFQLWETMLSSSGDISYDYLTPLSN
                     TSNTLPLVRRQDQPLPIHRIQITGFAHNNSPKHDIIANHYENGDTVLQLPLAGGVPGAN
                     DTEGLDLRKRFDNPGFKIAFTTRGRSQLTQAHQKSMALAGAATWAVYADNANHKMDDFI
                     GFAETDHAANFYYRIIPELRGFGTNYETVDICGGMASYL"
     mRNA            join(44433..44615,44671..44831)
                     /locus_tag="M747DRAFT_294481"
                     /product="hypothetical protein"
     gene            44433..44831
                     /locus_tag="M747DRAFT_294481"
     CDS             join(44509..44615,44671..44821)
                     /codon_start=1
                     /locus_tag="M747DRAFT_294481"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_294481-T1"
                     /transl_table=1
                     /translation="MGTNEKATTSISHSSSSATPSRTVTVLRNIVQSPWTLPYIAMVTP
                     LVRSIWNYMGWSNGGEVALSLSHGLLILYFIISQYVRRYE"
     CDS             complement(join(<46182..46577,46644..46952))
                     /codon_start=1
                     /locus_tag="M747DRAFT_369046"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_369046-T1"
                     /transl_table=1
                     /translation="MYNDNESLMVCDGVPLPSTVQLNPVKVGDISPCFSDQVDITLQRA
                     AETVHVMDTFPMPRREANSTDAVSMRNLEQRQTGACRMWSPAKESWRRRSPSELLAETE
                     NLDCGSAHYCTVGASQSKSYTVGWTATADASQWISGGFAVQASWTTGLDYQCTASSHQT
                     VCIWYNTAHTAYTAQNGLYNVCTGFNPNNDAGFVMFSPNQNNKGGGFYCVIGTCRSQGQ
                     NYWDKSGPAGGP"
     mRNA            complement(join(<46182..46577,46644..47151))
                     /locus_tag="M747DRAFT_369046"
                     /product="hypothetical protein"
     gene            complement(<46182..47151)
                     /locus_tag="M747DRAFT_369046"
ORIGIN
        1 ggttaccttc gacctgaatc atgtctggct tggttcatac gcgtcatact aaacatggcc
       61 acaccaagga agctacacga ttttccttcc cgtcacccag tcaaaagcca tggacaagct
      121 gcttgtttga tgtaacaaca acttctaata ggctcaattg ttctgtaaca ccttataggg
      181 tataataatt acatcggtag cgagcgatca agcctgtaag tagtataggt gatagtgatg
      241 ctcgaattat acatttttaa ggcgagtatc tagttaaatc atagctttat aatcggagtc
      301 tcccataaaa aaaagccatt ctaggcttaa tctccccaat tattgccatt gtgttgaggt
      361 tgtgaatttg cagccccaag gcctagatcc atggaggtgc ttgataacca tcacgtgact
      421 tgccacccct cccccctcat ggacaaattt tatagagtca gacgacacat tccattatct
      481 taccgtattc gatcctttcg aatggagatt ccctggtagt atatacaatg tatctccctg
      541 tcagacctag acccaagaaa accgatatta tccggtcacg caatgggtgc aagagttgta
      601 ggcagaggcg aaccaaagta cttccccctg ggtatgtttg acttggctgt tctgaagact
      661 gacataaggc tagtgtgatg aaaaacagcc cacgtgtggg acttgcgcca ggttaggcaa
      721 aacatgcgag cgcttttctg aggatttgca attccgtgtt gtgacttcct cagatcctcg
      781 aatgccaaag aggctgagag ggaaagaccg ctctcataca cgcctagggc taagtcacgt
      841 agaacctgag ggcgtttctt gcggcagtat ggatctgata aggtcgctac aacatacaga
      901 acgggacgtt ttctacctta cgtattggga agatcagtgc ctgccaactc tgcatcccat
      961 cctccgcttc tttacccagt cagcagcagc aaacgtgatg ttgaagaaca caatgctagc
     1021 cctgtcagct tgtaatctca gccgcctcaa cccagaagtc agaatgcgct cagagagctt
     1081 ccacatgggg aagttcagac ccaacttaat ccatcagacc agaagtcagc tttactattc
     1141 agctgcaata agcagacttg tcaactcgga tcaacttcat gaccagcggg tagcgataac
     1201 tgtgttagcc gttattgtta tcctttcgta tatggagtct tcaatgtcta attttacggc
     1261 cttttactgt catacggatg ggctctttcg ctttctcaca aatctgaatg actatgctca
     1321 agatgagaca gttcggggtc ttctaaccac atggatgcaa agccggcttt cggtttggtg
     1381 gatgcgctcc tactttagct cggtaaagct gcagcggctt ctgccatcga tccctctgcc
     1441 acgcatcctc caagggcagc caaagtcctt gcatgagcgc cgtgtcgaga ttatgagtat
     1501 aatgtgtgac tcgcattatc tgagtaactc ttgcatactc cgacactggg attgtgaaca
     1561 aagcacagag accgtaattc ctgaaccatc agacgcaccc ggcactgatg cattgcattt
     1621 ccacgtgctc ctcgcccacc aagtccagcg tctagatcgc tggatccagc acctctcacc
     1681 cgccgaacag ccattgatgg attcagcctc aacaggagat attaccactc cactgcgctt
     1741 cacctcccac gacgccgcgc taaactacgc ttattacctc accagttgta tcctacaatg
     1801 ccagactatt ttctgcaccc ttcctccaac atgccctact attgcaacaa gggaaggcca
     1861 aacagcagac ccctacgttg ggctactcct ccgcattgct aaagcctcgc cgccagccca
     1921 tcacctcaag caaaacatat acacaatcgg attcacaaac cttcttctca ccgccctcct
     1981 ccgcaccacg tctgtttccc ttgccatcga gatcgagaat tttgtacaga gcttggccga
     2041 caccctacca acagaagaag gcgggttccc aatttaccaa gccctagcgg taatcaagtt
     2101 gatcaatgtg cggaaaatgg cagggaagga tgtggttgcc gtttcgcagc cggtagatga
     2161 tcatggcggg gaaccaaaat tccaatctta taacagccag gctatacggg atctattctt
     2221 ccatgggaag gaacgcacgg gaggcgcttt attcaaagag cgagtagtta ttggccgtgc
     2281 gggcaagttg aatggaggag agtggagatg ggggagagga agaagacggc ctgttatcta
     2341 tgtgtcgagg ttcgatgggt tctgatctta actagtatac tttgtaattc tactcccagc
     2401 tcttttgttg tcgacagcat gatggtaaca tgaacttgta gaaccacgag ttaaggtttt
     2461 gtttcaaaat ttgcaacaac tttcatgttt ggtttatgaa gccctgacca gttggataag
     2521 tgtaatggaa acgtcagtag aaggaaattg cattcttgac acaagtctcg gcccggtgat
     2581 cactttcagc tatctgtgta caggtttcct cgaacatact tcagaccagt atcacacccc
     2641 acagtcacca ctgttttccc aggacccagt tccttagcca actgtatcgc ggcgaccaca
     2701 ttaagacccg aagaagtgcc aaccaaaaga ccctcctccc tcgctagtcg tcgacacatg
     2761 gaacgccctt ccctctcatc aatcgcccgt gcctcgtcat accagtcttt gttcagtaga
     2821 ggaggaggga atccaatacc gattccttcc accgagtgct cgccgccatg gcccttagtc
     2881 aaggcaggcg ccgaagcagg ctcaagcaca gctacatggc acgccggcca gctctgcttc
     2941 agagttttcc cgacacccat caccatccct gcgcccccaa ccgcgccaca aaaggcgtca
     3001 ataggttctc caacctgtgc tagtatctca cgaccaaggg tttcataacc tggaaagaca
     3061 tctggattgc taaattggtc ggcgtagtaa taagaagaag gatctttatc ctctgtggca
     3121 atacggcgtg ctcgctctcg catagaggga atcagttgcg gtgtgatttt cccattctca
     3181 ctcggcacga tgtccaggtg cgccccaaac gcagtcatgg tgttaagctt ctccttcgca
     3241 aaggcatcgg aggagactac acggaaggtg tagcccttga cggcgcagac gaaggcgagg
     3301 gacgacccgg tgctgccgcc ggtggcttcc acgactgtca ttcccggacg aaggtcatta
     3361 cgacgctccg cttcctcgat gacagagaga gccatgcggt ccttgtacga gccggtagga
     3421 ttcaagcttt ctagctttat gaacactcga gcgcagtcct gaggtactac gcgggtcaat
     3481 tgaacacatg gtgtgtttcc aattgcgtcg agagcactgt caacgcttgg tatgagtgac
     3541 attttgtggt atgttggagc tggtgaggac agagagaaag gaagatgctg gaatgaattg
     3601 ggatgcttag aggaactggg aagtgagaag atgatgtcga gtgactcaaa tcttagtgtg
     3661 gacggctctg cttgactgtc tctagcccta ggggttaaac ggattaccaa gagggtgact
     3721 attgcgactt gaggttacaa tgcgatccag ggtatggaat gttacggaac tctaccggaa
     3781 aagttcttcc cacttgccac atgaccccat attttaccga ctggatatgg aaggtccaac
     3841 caggtatcat atcaggtaca tgactctaga gtatctaaga ccagcaattc tgtccgagct
     3901 ccgagtggtt gcagaccggg ttgcaccttt actctcatta gactagctat agatagttag
     3961 cggagaagaa atggtaacaa tcccaaactg ccaagtcggc gattcactac cgagcctagc
     4021 cctttcggga gtacctgaac gaggctaacc agatatggta tagcgttgcg aatccaaaag
     4081 cgccacctgc aaaaactgtc gagtgtgtaa ttttcaggga ccgcatccct tctccacttc
     4141 cccgcctgga acaatgaggc aaaatcagat ggccgacggc aaccgtggca cataggccca
     4201 gaaaatgaca gtaatatact gtattgcagt tggatctctc agtcttttcg tgaaaggccg
     4261 aggtttcagt cattcaaata gttttcgggc aacaaaaaag acagaactgt gggtgcggtg
     4321 gcactctgga tccccagtac cttgcttggg tccacgttgc atgacctggt ggcggccaag
     4381 ggctgcttca ttgttttcac cattttctac ggtctcttcg ctagtgccta tattgggctg
     4441 ttctcgccgg ctctcgtgga actctttggt ttgcaggaga tgccccgtat cacgggtatc
     4501 atgtacatgg tgcagggagc ggctgggttg gtgggcaccc cggtggctgg agtcatggta
     4561 cgcacgtaca atggcgagac tacctcgcgt agctatttgg atatggctat ctttgtcagt
     4621 gcgttgatgg tggcatctac catgacggtt gcctgggcac gaatggaaca gggattcgac
     4681 cgtgttagtg gccatcttac ctggaagtgg aagctctagg cttccgtgat aatgtgcata
     4741 ataccaatat ttgtaactta aatgagtata ccttctagtt tgggtaattt ttatcccagc
     4801 acagggcgta gccagcagat gatgctggtg cgctcatggg gccttttatg ccccacgaaa
     4861 actctaagat agaagcacca tcgcttcggt ttctaagctc ataaggcaag attaacagtc
     4921 tatgctgtga actacgcggc ttcatatgac ctagacagat acacgcgccg acaaagtcac
     4981 cagtggaacc ttatgacatt aaatatgtta tctgggagag aagtgctgca actattcgaa
     5041 gccctaaagg ttggaaccat ccaccactgt cggtaggact cggctcggct gtggaaatgg
     5101 cggcccgcat acacagtgtg tgttgcaaaa ctccgagtga gaaatccgac tagaaactaa
     5161 gaggcagaca aaagcgtaag gctgatcatt actgagtggc tatcagaaat acgcaagcgg
     5221 cttgccacgg ctcacggtgg gaaggaaacg cggctaacta ctagtaagtt atggctgtta
     5281 ctggcaagac aaggttccct cggtccacat ccaggtccta tcggccgaaa aggtctgtct
     5341 agtggtttcc aagtgccgca gtgtattttc cgagattggt tgatgaatgg ggccaaggga
     5401 aagccaagaa tttccaaacg tgcatgctca ctctgaggaa ctctctgcga tttgatgaac
     5461 cactccacgt ccacttttac ggtaagcacg gcgccgattg tcacaggctg tggaggttca
     5521 tgtgacaatg attcatcatt ttccagagcc ctgggcatgc ctatcgcgag cgaccaaaat
     5581 tgctcagcac cacaatgtcc agaacatgct ggtcattgaa ctgtttagaa cagtagttgc
     5641 taattctgac taaacagttt tagctaccca gtgcattatc ttctactctg taacattact
     5701 ggtaacagca ggatcatccg cacaactcct atatagtttt agttttgtat aatgtgctga
     5761 ggtattctga cacagccttc tttacactac agaggtctgc tatcatccga cctatcaatg
     5821 tgaaacacca ttatttctag ttatatgaaa ttgatcacat tcagtacgaa acttatagcg
     5881 aacgacccta ctccgatctc ttcgaaatcg caggcaaaaa gcaccaacaa acaaccatcg
     5941 ctgcatagag cgccaaacaa attggatgca ggactatcgt tcccacctct tgtgacagaa
     6001 tacccgtcag aaagggaaat actgcacccc cgctacttcc cagcgcagtg atgaagctca
     6061 tgctagtcag ctgaatgctc cggggtagta gtttcgcaaa cacggccgtc gagcatggat
     6121 acatgggccc tagcagcaag cccacgaccg ccaccgccac cgcttcgccg acaatgttgg
     6181 ggatcagcca agtcatgagc tggaacgcta tcgctccgac aaccagcagt cctacggcaa
     6241 gctcctcacc aattcggttt gccgggtata caaggaggaa gcgcccgagg gtaattccgg
     6301 cccagaagcc agcgctcacg tagccgacac gtcgcgaatc acctcctcgg tagttgatga
     6361 ggaatgagac gatccagccg gaaatagaga cttcggctcc ttggtatgcg aagataaaga
     6421 gtgatcctag gatcgttgtg agattccgga tggctcgttt cagggtttgg aggcgagtgt
     6481 gggagttatg ggaatcattc tcgtttggct gggccgtctg agaagcaagg gagggggatg
     6541 tttgctgagt gggcgccctc gaagcggcac cttcgtcctt ataattgcga aagacgacag
     6601 ccgcaagcaa catattcaac gtcgaaatca ccagtgtgat gaagtagaag tatgtccagc
     6661 ggatgccgtg tgacaccatg gccgtggcca atagtgggga gatcacccca ccgatgccat
     6721 acgcaccgga gaaaaagccc agtgctgtgg catagctgtt taggtttgcg cagaagacat
     6781 tgttaagcgc gatgcttaac gccatcccga agccgaggag gagaaacgcc gtgacaacga
     6841 ccggaaaggg cgggtggcat acgatggcaa cgtagcccgc tgtgacgaga ctcatcgaga
     6901 gagcatagct tttggcgtgg ccgattcggg cttggattgt gtgagtaagg ggcgcggcaa
     6961 gaacgaatcc gacggcgttg gcgatgaaga tcagtgagat gatggcgtag ccaatcccgt
     7021 aatcatcctc aatataaggg attagggcac cgggtgcact gtcgttcatt ccgttgccaa
     7081 agttcatcag gcacgcgcta gctagtcgcc agatcgtgtt cctgcgcggg tgtatcgagg
     7141 ctgttttcct atttgtgtct tgagctccat agttctctgc tgctgctgac tgcacgacgt
     7201 tgaacatctc gtcgacttcg gagggttttg ttgacccggc atgccttgtg cgcctactat
     7261 gcggcgtatt ggcccctatc ggttcaatgg aatgcaactc cagacttgac aatggggacg
     7321 aggcatcgtc ttgcgggact agggcgacac gtggaatttg tggaaatatc ggttcggctg
     7381 cggagagccc ggcagacttg ctggtcatgg tcagttgagc aagcacggat atgcccttct
     7441 ggaagaatat ataaggtgta tgtcctctga atcacattaa tggaaagaga acagcccgac
     7501 gcgacataga ggaagaccag gcttatgctc taggaggata tcgccaggga agttcctcat
     7561 gcggtggatt acaaatcaac cggctcgtcc agcagatcca ctgggtatta tccgggaaat
     7621 gggaaggtct gaacctacga gtgctgctgt gtggcgctag gaagaaggct gttggtacaa
     7681 tacagaagga ttttacggtg atgtccaatg aaagatgaat tcgcaggatg aggaaaacgt
     7741 aaggggaaac cagagaagcc agagagaata gctgggtata gatacatctt acggcccatt
     7801 acccaagaga tcagcacctg gctaatactt cagatctaac tgcttggttc agatcagacc
     7861 ctagggaaaa attggttagc gtcgctcttg ttcactgcat tcggtcgtcc ccgcttctcc
     7921 gcaacaaaag agattacccc ctggctcatt gtagacggag tcattagtat tgtattcctt
     7981 tttttttttt tttttttttt tttgaggact accctcccga acaaagtgtt gcgcctttct
     8041 tctaaaactt cagctgggtt cctctggcgc tttaggcacg atgaaatttt caaccttgta
     8101 agggcagtaa gcgctcccta gttagttaag tgactgttgc tagcttacta tataacaggc
     8161 tttatgcaac catcccctca tctatatgtc caatagtgta tataaaccag acatgatatt
     8221 ctctcccact gtttgcctgc tcttcgttgt tcaatgttct cctgcccaga tcatcctgcg
     8281 aagactgatg gacacttgag agtctacggt cgcaacttta ccgaaactct tccacgaatg
     8341 cccaaagcgc agaattatac gagaaagcca gctcagccgc gagtttgagc gggcaaggca
     8401 tgtaggtgat gtaactagaa gcgcatcaga tgtgatgctc agcatcgaat tccctttata
     8461 aattgcgctt agagtgataa atttattgca gtccccgcaa gatcaggcgg ggcacatata
     8521 cccgaaagct acgtcctcgc aatgtcgacc accacggtca cttcatgcaa cacgccgcta
     8581 ctgtcgcccc cgtccagact cccatatccc accagacaac tactgcagca gcgtcaaatc
     8641 ctcagttttg gaaatgcact atacttactg tgttaaccaa tgtcaatcag ggattattct
     8701 cttccgctga atagtgctgg acttgccgat tcaccgttct aacagccctc tggaggcttg
     8761 gataaatatt actatatttt atagaggtat ctcctgttct gccatgttcg accacttcct
     8821 gaatagccac aaagatagta cggaatgtaa ttgatgaata ctggattttt tttaccttgg
     8881 agaatccttt cctttggcta tggtactggg cgatttgagt aaggcccgac taaatctgta
     8941 ttatccggga cctccttctc ggcaaaggag caccagcccg atttctttta attttctgca
     9001 gctaagacat attctgcctg aagatctgga gcatttgcgt atccaagggg tgtttaaatg
     9061 ccctgataaa gtccatctgg acaccttcct gactgtttcc ttagaatatg ttgtatcctg
     9121 cctatcatcc cacgaaccgt caagagcttc tccggcagca tgcaaatgga accattcact
     9181 aaccttactc cattccatct gctttgttga ggacgtgtcc agacttcctt gaaagcttgc
     9241 gccaacaaac atacgcgcag taccagatta agattgccag gctctcgcta gttttgcgtc
     9301 atgaacaaaa cctgtactcg ggcttgctaa aaccaaagga aacatcacaa tgaagacggc
     9361 tccttaagtg gccctttcca gcttgctcct ccaggctagc cgcacatatt tttaacgtta
     9421 ctttaagtgg aggatgccct atatcagtgg ttgcttgtat aggtgtttta ctgtgatagt
     9481 aaacaaaaaa aaatgacact gacaaaggga gtatttggct tttagtcagc accaaccaat
     9541 gccaaccaac gagcatgtca tttgatttgc cagcggcaaa agcttgctgg agcaaaaaga
     9601 tgtgaagaat agtcaaaagc aaaaaagaga tggtcccaga ggggctcgaa ccctcgactt
     9661 tgacgttatt agcgtcacgc tctaaccaac tgagctatgg gaccgagttg ttgaaactgg
     9721 ccgcttgaat gaatctgaag acgccccgca gtggcccatc gtccgcaaat ggagccgtgg
     9781 cagacaaagc taatcctgtc cgcccttcag agcgcggcag aaaatggtcg ctgcggtgac
     9841 gcccacatag tagtacttgt aagtactcat tccgcagtaa tgtactcgct acttttgtat
     9901 tctaatcatt atctctttca atcgagccat aacaatgatt ccattcctgt tgttccattt
     9961 ttctgacacg ttaggaattg tgcagttgtc gcgggcaata gtccgcagtg cagggctgcc
    10021 atttattttg ccagatcatc catgatatat ttttctcaac ctcgatacat ccgccacgac
    10081 ttgctagtac taagtaagta ctaagtcaag cactatccga aatgcttaaa tgaagtgttg
    10141 acgaaagttt tcattggcat gaggtatgac gatcgtgctt cagcacgcgg tcagataata
    10201 acaatgtctt gaaagaatat tctctatatc acactttcat gctctgggca tcctgcaagg
    10261 taactagttg tgtttggccc gctttgaccc agattgcgtt atgcgcgggg ttattaagca
    10321 attaccttga acctcactgc gtcagccgtt catctgcttt gaaattgaag cccgcaaact
    10381 catactatac tagcaatatg cgaagtctgg tgtatctgtt agccctggct gggcttacta
    10441 cgaaatcgct agggcagcag aagcagcaac agccgctttc tgcgaccgcc aagcccaacg
    10501 tcgtcttcat attaaccgat gatcaagacg cccatctcgc ctctttggat tacatgcctt
    10561 atgtacaaaa gcacctccta gacaaaggaa cacactatcg cagtcattac tgtacaacca
    10621 gtgtctgttg tccatcgcgt gtgacccttt ggacgggaaa gctggcccac aatacgaacg
    10681 tcacggatgt caatcctccg catggtgagt gtactacaca tcgtcactta tatcggggga
    10741 tattctcata cgctttcagg cggctatcca aaattcatct ctcaaggtct aaatgacaat
    10801 tatctccctg tttggctgca ggaagcgggg tacaacacct actacactgg taaactgttc
    10861 aacgtccaca cggtcgacaa ctacaacgcc cccttcccag ctgggttcac cggcaacgtg
    10921 agtcatccag cagactttct attcagtcgg cactctaatc tgtcatgtag gacttcctcc
    10981 tcgatccatt cacatacgac taccttaaca gtaccttcca acgagaccac gaaatacccc
    11041 aaagctacga aggcgaatac agcactgatg tcctcgcaca aaaggcatat cgcctcctca
    11101 acgaagcagt cacggcccaa aagcccttct ttctcacggt tgctccaatt gcaccgcatt
    11161 gcaacgtttt catgaatgga actggcttag acgccaaccc taaattcagc ttcagcgcac
    11221 ctatccccgc gaagcgacac gagcacctat tcccagatgt caaagttccc cgcaccccct
    11281 ccttcaatcc ggaaatccct tcaggcgcca actggattaa gactctcaag cgacaaaacg
    11341 atactaatgt tgactacaac gatcattttt accgccagcg tctacgcacc ctccaggccg
    11401 ttgacgagct ggttgatggc ttatttacac gtttgaagga atacaatatc cttgacaata
    11461 catatatagt ctatagtagt gacaatggat accacattgg tcaacaccga cttcagccag
    11521 gcaagtcgtg tggatacgag gaagacatca atgttccttt gattattcgt ggtcccgata
    11581 tcgcgcagaa tgtatctacg gatattgtca ccacgcatac ggatcttgct cccacttttc
    11641 tcgagctgct gggtattccc cttcgagagg acttcgatgg caaccctatt tcgttgacga
    11701 ggagccagat cgagagggcc caagaagaga gacaggaaca tgtcacggtt gaatattgga
    11761 gatatgcggc gggcgagggt atatacgact gtgcgtactc tactcctaca ccccactctt
    11821 tgaccatggc tgagctaatc ttgataatga aagttgacct atcggcatac aacaacacat
    11881 acaaagccct ccgcatcaag ggaattggat ataatcttta ctattccgtt tggtgtaaca
    11941 atgagcatga actctatgat atgactgtat tggcccctcc caaacccatt tctcttggga
    12001 aatctgacca aagagacaga ctgaccctca tcaacttcat aatctccttt ccgcaattga
    12061 acaacccagt gcgacctctc acaccatctt aaacgttgat ctttccaaag tcgttcagcg
    12121 actcgactcc cttcttctcg tgctcaagtc ctgcaaggcc caagtatgcg tcaagccatg
    12181 ggacgccttg catccgcgtg gggaggttat gacgttgaaa gacgcgttgg atgtgcacta
    12241 cgatcatttc tatgaggtgg agcagacgac gcgggtccag tttaacgagt gtgcgcgtgg
    12301 atatttccta gatgcggagg gcccgcaatt tgactcaggg acagattatg aggttcttcg
    12361 agatggtttg ccgtggtatg agtgggttta aatctgtgga gtgtggaaat attgagggaa
    12421 atagttgtta cacatgtgac gacattcagc tgcatgggtg agtgttatgt gaccatcata
    12481 tcctacatct aagttttgtg gctacttata aatatgcgaa atgatgggga atcggggtct
    12541 tttcttgaga gacgcaatat tataaacgta ggaacctttc aaacgcggac tagccgttga
    12601 ggagcctcga attctgttga accattcgca agaaggaggt gttgacgcgt tgtttgtgta
    12661 gattgcgagg cctcaggcag caaactatta tatccacagg gcaagtcgga tatgctaggg
    12721 gctaatacct gcatcgcaga attgaacttt gaagagagcg agtatcgcct ttgagactaa
    12781 attggcttag tttatacaag caaaacatcg tttttgagca actttgaaat tgtccaggag
    12841 attcatacct tgttcaacgc caatgccaag actggggata gaagccgagc cagccccgtc
    12901 cggaacggtc gggtaagccc atcaggcggt ccaaaatgta ttccaggtgc ctgtaatgac
    12961 ttcaccctct taggcacttg gttgacggga tcaagtgggg atataggttc aaaattggct
    13021 acatcatccc gtatgcaaaa ctgtaattgt cttcaacccc ggaaaccgtg caggaacaag
    13081 gcctgctaag cacgggagac acgagtgggt caccgtcgcg gtggagttcc cgaaggagcc
    13141 gatttattat tattccagcc cgtctgccaa tctccccatt ctttctcatt cccaactccc
    13201 ccatattgat cgccaggaac gctcgcgaca atggcttccg cgatttcgcc tttctggggt
    13261 gccccgacct cttatttgaa gtatgtcaat taattaatag ccaattgaag tatacgtcgg
    13321 agactaacca atgtcgacag cttctgtgaa gaggtccgtc tacagcaagc gcaatctggt
    13381 cttttcttgg cccacaacaa taatcgctga tttgtcctct aggactatgt aattacgcga
    13441 tatgttgcgg agtttattaa tactcttagc agctttgtct atagtgcgtt tattcccccc
    13501 ttacagtagt ccacaaatta acactcttct ctagttctat atggcatcta cggtctctgg
    13561 cagctccaca gcagacgcca aaccgggcca cgctcaatca catactgcgg attgattggc
    13621 gtcggtgttt gctctgccgg ttaccatatg actctgaaat atcacaccca gatgtgtact
    13681 gcctccctct attcttcagc ttactcggaa tgataattat cgtgatctga gctgatccgt
    13741 ctcaacagcg gatgaacttt ccatgcacct cttgactaca ccactcctct accgcattct
    13801 atctttccag gccacccctc agtacacaaa gacagtagga atcattctct ctgtactgtt
    13861 cacgatcgtc atggtcgtcc acatggtcat ggatgagttc ctgcttcacg ccgtgacatt
    13921 cggggccgca gtgtgtctga tcacgactcg cacgctcaag atcattcctc gcgagatccc
    13981 ggacgttgag gcccgtaaaa ggattcagtc cgtggcgctg tttggatgtg gtatgttatc
    14041 tacactctta ttattggctt acctactagg tgaatgagat gagaatgtag ttaattctaa
    14101 catgtatgca gcaagcttca tcttcggata tctcgtctgg ctgattgacg agtttgtgtg
    14161 tcaatccttg atcgtagcca gacacgcggt cgggctaccc gtggcgttct tgcttgagct
    14221 gcatggctgg tatgtagatc tttccccatg gtccgggata aacttgaact tggctaacaa
    14281 gtcatacaag gtggcatgtc ttcactgcca ttggtggata tatcgccgtg gcggtcattg
    14341 atttgattac ttccggggaa gtgcaacggg actcggttgc acagctcgcg tggccgctgc
    14401 cgactgttgc gaggttgctt gggcctgctg caggagagac gaagcgggag tagaattgtg
    14461 cagggattag tgttggggaa aggggggcgg gggtaagaat atagtacgaa tagaagaaca
    14521 gtggcatgga tggatagttg aggcggagtg gttgatagag agacgagtcc cattgatgtt
    14581 tatagaatga tatggattta ttgtgctctc cactcgggac atgatttgta gatgattgca
    14641 agtaaacgag gagggtgtgt ccagaaacaa ctaacacttg cacatagaaa accatgttct
    14701 attgtgtcgc tgagtgcacg gtctctaaac tgaaactagg atactctgtt tcaatccttc
    14761 gcagtaaata ccgcctgctc taatgtactg tatacttagt agatcttgta tgtactttgg
    14821 ggtccctatg gtatcccgat aggactgggg catcagaaac aatagaaaac ccacttaagg
    14881 tgcgctaaga caaaatagac accaagaact gggacaaatg tgttagctcg gcaatataga
    14941 acgacgtgaa tcattttgtc caaacttcgg tggatgacgg tggagacgag cttttcgacc
    15001 aaaacacccg tatgactctt tcatcgccaa gcatgatgtt acatatcatc tggctaacaa
    15061 agtcagatgg actgagatgg aatgggctgt tctttggcca atgaaactta cccaaatgtc
    15121 aagtttgctt ggatctgaaa ggtgtcaaat ccaaaaccgg gcactaggtt aaatgatcct
    15181 tgacgtcaac ctgatacctt caaatgaaag tcaaaggatt tataccaagc cagtcatgcg
    15241 gttaacagac aaggtggctt cccagcaatg agtgggctga tgcaccgact gcaggcgtct
    15301 cggaagcgct gaatcattgc ttatgtcctc gggataggaa gtttacgtgg ggacaattca
    15361 tgcatgaagc ctataccaga tttagactag ttcaaacgtc tacgcgtata tcttatgcag
    15421 aagggacgat ttgaaccgaa gcatactgat attctcttgt ggttgggctc agtcgttttc
    15481 gattggaagt ggatagtgat gacgactctg cgtgggctgg acaaggaacc aaaaacacgc
    15541 ggccaatcag ttagggctga tttgacattc cccgcaactc aggtagagta actcaatgca
    15601 gctatccaca ggagtaacag cttctgttca attatgtgtg gttgtggttc atattgcgag
    15661 tcttgttcct tgtgaacaac actatcttag ggatggaaat ttcacctaaa cttagcagtt
    15721 gctttcatcc tgtgcttacc acttcagagg catatcgatt attcgatgca tcgtctacta
    15781 cgagtattat gtctcggata aataatgtcc tgcattggag tcgagaccga cagatcaaac
    15841 atactggcgc atcaatgcgt tcaatgccag tgcacaaact ctcttattca tggtaaatga
    15901 tgaatgatcc taatggatga cgagacactt cctgctatgc ccgtatgcaa tgcataaccg
    15961 ctgaatcagt ggggttccac cctgacggcg cttcttgcag atcaagcggg aaatgcggca
    16021 tactaacgag gcattgtttc aactacatcc tggccatctc aacgcctaaa gcccctcaca
    16081 atttggaagt atttaagtaa gtatcgatag gcgtctatcc tcatccgttg ttggaattga
    16141 tgccgctacc ctatctcatc ttttttgtta gcactactac gttatgttct ttacagacac
    16201 cccttttagg cccttgcgtg caagcatgga gaacatgctg ggttatacct cgatgccagt
    16261 acccgtcctt gtatcgctgg ctttaggcct cgcgtttctc ctacttcaaa gcttcagata
    16321 caaggacccg gccctgaatc caaagaagcc cttcgagctc acgtctacta gagtaaagca
    16381 agaatacttc tccaatgcgc gaagactgct atgggattgg tttacaactc attcaaatac
    16441 gccagtgctc ttgcataccg acactgggaa agtgacaatt ctccctccga gtatggcgaa
    16501 tgagatcagg aatgacgacc gcctgagctt ctctcgctgg acattcgaag tgtgttccga
    16561 ctttcatgtg ttttatgttt gatccggagc tcgtgtgaaa gtagctgaca agatgccagg
    16621 catttcatgg caatctacct ggatttgacg gattccgcga aggtagtcaa gactcgggga
    16681 ttgtccaggc tgttatcgga aacgacttga caaaatacct gagttagtta tcggacttca
    16741 cggcactggt ggcatgactg tatactaact cacaattcgg catcttggca gacaaggtca
    16801 ccgagcccct tgccaacgag acatctgtcg ccgtccgtga actgttgaca gataatgaag
    16861 gtagacaatc tcatactttc caattcgacg ataggaatgc taatgtgtgt catgattaga
    16921 atggcacacg atccagttga gaactgtgat ggtggctctt atttcccgca tttcctcccg
    16981 tgtcttcctt ggggaaaagt tgtgccggaa tgaagaatgg ctgcgagtca ctcaagacta
    17041 tactactgat ggattcttag cggcggaaga gcttcgcatg tggcctgcag ctattcgacc
    17101 catcgtacac tggttcttgc cccgatgccg taagcttagg gcccaggtga aagtagctag
    17161 gaaagtcatg ggaccaatac tagaggagag gcgtcaattt aagaaacacc ttcatgcaga
    17221 gggtaaacaa tcacaagggt tcgatgatgc tatcgaatgg tttgagaagg ccgccaaagg
    17281 tcgtccctat gaccctgtca gcgcgcagct tatcctttcc gtggcggcca tccacacaac
    17341 ttccgacctg acatctcaga caatgaccca tctcgtgcaa aatccggaga ttttggagcc
    17401 tttacgcaag gaaattgttg acactctcca acagcatggt tggaaaaaga ccgctctgta
    17461 taacatgaaa ctgctggata gtgttatccg ggagagccaa aggctgaaac caatcaacaa
    17521 cggtgagcag agcataaacc catctgtttt gataccttcc actggtttgg ctaaataaat
    17581 tgtcaacagc ctcaatgcgc cgggtagctc tcaaggaagt gaagctctcc gacgggacgg
    17641 tcatccccaa gaatggcatg cttgcggtat cggcccacaa gctctgggat gatgacacct
    17701 acgaaaatgc agctgcctgg gacgggtacc ggttctacaa gatgcgcgaa gaccctgagc
    17761 gacagaccaa ggcgcagctg gtcacaacgg ctccggaaaa tttggctttt ggacatggca
    17821 aacatgcttg tccgggacgc ttcttcgccg ccaatgaggt taagattgcc ttgatctatc
    17881 tcctactgcg gtacgactgg aagctattgg aagggacggt accaaagatt cgctatggtg
    17941 ggtttagtat ggcagttgac ccgagtctga aaatggaggt taaaaggcgt cgagaggaga
    18001 tgggaatata aagcccgcag tcggtatcca tcacagagac ctttttattc gctatacaaa
    18061 tgtacagatc atgaagggag aaaacaatgg ctatgcagat accaggcatg gaatggagat
    18121 atgcatgtag caagaggaaa cagaacccac aattactgga cgagttgttg ccgagaatcc
    18181 accgacgtaa aaccggaatt tccccgggca ggctgcaaag gcagtggagt gggccaacgc
    18241 cccctgaagc ccttctggaa ccaacgttat tcgctctgtt taaaatttaa gcatgccgct
    18301 ggtgtctacg ccgcattcct caactagtta tctagccttc caggcgtgcc agtgaccaaa
    18361 ctccacctca tccaccttaa tcaaagcacc tgtactgtga gataatgggc gcttccctca
    18421 ctccatacac ccaaacgcta tcgcggaaaa gccatcgcaa atcccgtctg ggatgtaaga
    18481 actgtaagag gcgtagaatt aaagtcagtt cccgacgcct tctccactct gggcgcttca
    18541 atgagtgaga gatactaacc gatccccagt gcgatgagat caagccacac tgcaccaact
    18601 gcctccgcca ttcaatagag tgcgactaca gtttcaaacc ccaaactaac tccagctcct
    18661 ctccacaatc acagcaatca gactcggtat caccaccctc acagggcccc agcacagata
    18721 gctacacctt ctacacatcc tcatccgtca actttcaacc cccaaaacga ggccatggca
    18781 cacctctcac atcaggacca gacacaaccc aaccatcacc cccatcaaac aacgacctag
    18841 ccaagcgccc cttccaatac acagccctgg acatgctcct ctttcaccac ttctccactt
    18901 cccctgaact aaccggcgcc caaccaaaag cccgtcagca attatctcaa atcgcttttt
    18961 cccaccacta cgtcatgcac atcctcctcg ccttctccgg cttccacctc gtgcgacgat
    19021 cagacgatca gcaatggtcc caatccatgg gtttcacaga agcagaaata tacactgaag
    19081 ccgaacgcca ctttaacgtt gctattcgag atgtctcagc caccttaccg caccttgacc
    19141 gcgacaacag tcccgcgatg tatgcctccg caatattcat cttcatctca agtctcgccc
    19201 gtggccctca accgggggag tacctcgcgt tccggagcga tggcacccca ggccacttgt
    19261 ctttgttcct cggtgtgcgg tctgtattcg agctatgtag cggagatatg ccaacgagcg
    19321 ttttctccat ccatggagag ggcgatgatt cttcttctcg caccacacct caaaccgaac
    19381 atgaaaactc ccatatcgca tcacaaaaca aaaccaagtt agaagattac ccgcaccacc
    19441 tagaaactta ccgcgccctc cttaccacaa ccatccccat cgacgaccca cggctctcaa
    19501 tctatctgca aacactagac cgactaggcc acagcctcga cgccatcatg ggtcccgatc
    19561 cgcagggtac aatgggaatg gctctcttcc cgcttgtctt tgcgtggttg tatcagttgc
    19621 cggacgcagt ggtgggtgat ttgcagcgga gggagccggt ggcgttgatt ctgtttgcgt
    19681 tctttttgta tccgcttgat cggctggatc atgtttggtt tatttgtggg tggccgcggc
    19741 atattctcga ggggattcag tggcatttgg atggcaggta tcgggggtat attcagtggg
    19801 cagtggatca tgttgggggt ggtagattat cagagggttt gggggtaggt atggaggttg
    19861 ttagtagatg aatgtcgtct gtatacttgt tgggataata tgtaatggac attagcaaga
    19921 tgagggtgta aataaactac ttcctttatg atatcagtct atagagtact aagaagagta
    19981 gtactcaatg tgggtaaata tcacacaccc accgccccct caactaccga cctcgccaac
    20041 aacgctagac tcatcctcgc atccatcaac tccaacatac tcacccccct cccaaacgcc
    20101 ccctggaacc aattgcgaaa ctccgccgcc agcaaactat caatgccatg ctccgccacc
    20161 gtcttgttgg gattcacgct tcccacatcc acaaacaaca tgcctgccac ggtggcctgg
    20221 atggcctcag tcacgaattt gatggtctcc gtccatgcat cctccttgga atctttacct
    20281 cccgcacgga gcgtcgcaac ggagtggtcg aattgtcgtc tcagttgggc agtaggtgat
    20341 gcgtctgagg catggatgtc cgagctactg agagaagagg tagcggacga ggcgtcttct
    20401 agggcacgca acattaagga gacacgagag tcgtggtacc atctgggaat ggtagaagag
    20461 gcgagggagg cagctgatga ccgggccatc ttggcgagga cggctgggtc gatgccagtg
    20521 actatgtggg atgcggagag ggggtcatcg gtatggccga gccagagggc attgggttgc
    20581 tcattcacaa aggctggctc gagcatgcgc acgacctgag ctcccgtcat ggtttggcct
    20641 ttggcgcgga cgaagaggtt gacggtgacg gggtcattgg ttagcgggcc caggtcgttg
    20701 atgaagccta gggcgacggt cgtggcaggg agaccgagcc ggcggcggta gcgggcaaag
    20761 tagtcaaggt agttgttggc agcgagatag gtgctctggg tagggaaggc atagacagtt
    20821 cccaaggagg aggtcatagc gaagaagtcg agagggatgg aggtcgtggc atcgtggagg
    20881 tgcttgacgc cgaagacctt ggccgccatg ccttggttga attgggcttc ggtcatcttg
    20941 tcaaaggaga tatcctggta ggatacggca aagtggaaga caccacgaac aggtcgtgtg
    21001 ggatcaacat gcgcagatcg catggtgtgg agcacggcgt cacggttggt tacgtcgcag
    21061 gcaacgggct ggactcggat gccttgggct gccagctcag tgatcatacg ctgtgcttcg
    21121 ggggcaaggt tgcttgcccc ccggcgggac caaacctcca tgtcgcgagc accacggctg
    21181 ctcatccacc gcacgatgga gcggccgagg ccggtcagcc cgccgacgag gatgtagcgg
    21241 gcggctgggt cgaagcgcgc cggggttgcg gatgaggtgg ggagagtgcg cagcaaggtg
    21301 gacgggtctt ggtaggtaat gacacgcttt ccaatatggg tgccttgcga gaactgcaag
    21361 agagtttggt ccaggtagcc aatgtccgca acggaatagg gcttaatggg tccgatgtgg
    21421 ccagcgcgga agtgcgcgtc gacggactgc atcagctccg ccccgaggac agagtcgcgt
    21481 tccacaacga ggccaaggtc aaaggaggta aacccagcac tcttttggaa aagttccagg
    21541 cccatggttt gggaactagt gacatccagg cgacccacgt cgactaaatg acccaagggg
    21601 gcgagggctt tgacggactc gtacaacata tcgccctggg cggtgctaag gatgacatca
    21661 aaccctccat gttgctgagt ggcgcggttc agactggcca agtcgcggga cgagaagatc
    21721 tgcgatgctg gaacacccat gtggtctgtc aggaaacgga ctttgtctgc agtgcctgcc
    21781 gtcgcgtaga tggtggcccc cttggaccgc gccagctgga tggctgccag accaaggccg
    21841 cctgtagccg attggatcag taccttgtgg ccaggcttga ggcgagtaac atgctcgaag
    21901 gcataaactg cagtcatata caccagcggc atagtagccg cctcgatggc gttgacgtcc
    21961 gcggccagct tctgtgccag acctgcgggc acacgagtgt gcgtgccaaa gtgtcccttg
    22021 cccattccat aaacccggtc gccaatagat aatctagtaa catcagctcc tacctgggta
    22081 acaacaccgc agtattcgtt ggagaggttg ttcgcatcaa atcgaccgga acacagcccc
    22141 aggtctttcc agttgagccc gacagcatcc accttgacgt cgatataatc ccgaggcagg
    22201 ggttgcaaca gctctgtata cggacggaaa tagagggagg tgagaatacc aggtgtctca
    22261 aaggccgctc gtacgggtcc aaggctgctc agtggccgtg aggacacgtc aacttcctgc
    22321 ctggtgggag ccacctccgc gtatccctgc agctgcccat caggcacgat ccggctcgtc
    22381 cacatgcagc cgtcttgcca aaccaggtcc cgattcacct cgggaggtcc tttatcatcg
    22441 agggtgggct gcaggaggag ctcctgttcg accaagcagc ggaccagctc gtccatctcc
    22501 aggccaggaa cctgaaagtc ttccgcatca acgtcgactg acaagaactg ccctgcggga
    22561 ttctcagttc ccaaggtacg tagaagcccg ctaacaaatg cgccgtcggg atttcggccc
    22621 ttcactaggc cgcacgaggt aacccaaacc atgctcgccg tgtttgcagc tagatgttgg
    22681 aatagtccca gtcggcgttg atcggcggca aacagaaggt tttctccgtc aaggaaagcc
    22741 accacgcgag aattgggagc gagtacgttt attgcttggt ccataggact gatccggata
    22801 gataggccgt gctgttccat agcccgggcg agatgatgga gaagcgctga agtgccttga
    22861 gacccgtgta gaaggtggac cacagggttg ccgctcttgg tagttggtac cggatcgggc
    22921 agggtggata ggatgatggt ggagtgcaga tcagtttcgc gacagactag cttatatcct
    22981 gagtcgaatc caactcgccg aaggcattgg tcccatgcca gttcgctgct attcatgcgg
    23041 tccactagta caaggtggcc cccgggatgg aggagcttct tggcgtttgc cagggcctgc
    23101 tcagtagccg ggccatgttc cacattgctc cagaggatca tgtcgtaggt ccctatttgg
    23161 aattcctgtt ccgagggatc ttggctgata tccagcacgg agtatctgac gtcgcggaaa
    23221 gctgagacag tctcacggaa ggagtccagt cgctcggcag aggtgtccgt tgcgacgtat
    23281 tcccggtagc gcttgatgcc attgtggccg acaagggact ttagcactgc ttgaccagca
    23341 ttccggtcat cgctgccagc gctaagctgc aggattcgaa gatctgggtt ggcatggcct
    23401 acgaggtcga tgaggtagga gagccgagag aaagtcgtgg tcccgtccac agacgcaaga
    23461 agtttgttcc actgatcccg actcaatgtg cgactatcag gcctccagac aagacgcgcg
    23521 aaaggactgg aataagcttg gccagaaaaa tcctgtgcag aggactgctg ctcattgttc
    23581 aggctggtga aacgcatgtt gtccacgtcc aagatagcct cgccggagtc atccaacagt
    23641 tgcagttggg cgtacgctcc acgcaaccca cgtagctcgc cgcgcgatac ccctgtgatc
    23701 cagtcacggc cttggaggca gccaagtttg aaccgcatct gatcgaaatg gataggcagc
    23761 tggacactgg ccgtttctgc ctggccgcca ttacatgcca tgagtcccag gcggataaca
    23821 agatccaagg aggcggggtg gatgggatac ctggactcgc ctccagggaa caatcctgca
    23881 gtggtgttta gcgatagctt ggccaatgcc acgttgctga acgggtcagc ccagatatcg
    23941 gaataccctt ggaacgaggg cccaaactgg agtcccatgt cagcaaagcg agtgtaccag
    24001 gcctgcgcat ctacagcgcg tccatccatg gtagttgtat caatggccgc aggcgcgtta
    24061 aaggcaacga catcaacctt gactagacct gagcagtgtt ccgtccactg ctcggagtcg
    24121 ttaacgaccg aagcgatgga aaagcttgcc catccaggag atgcggcggt ggcaccatcc
    24181 tcgagctcca tgctgagcac gatctcaatc cccttgtcat cttgcgggac aaccagggtc
    24241 ttcttgatcg agacgttccg gagagtcaag ccagcaacag gtaacgcatc ggggaattcc
    24301 gcataggctt gctctgctgc gagcatggcc atcacaatat gcgccgctcc gggatgcaga
    24361 acgtgaggag gcacgcgatg gtcattaagc catggcagat ccttcaagcg gagtatgttt
    24421 cgccattgcg gacgcagtcg agttgtccct ggcacacggg ctccaagcag atcatgccgg
    24481 ggccagcgcc ggagtcggta ctccttgctt agacggctct cgtggtactt gataggccca
    24541 taggtgtacc ggtagggcgg caggtcaata gccatgcatc catgtatgag cgttcttttt
    24601 cccgcaccat gcgactcatc gacggcgttg actgccacca aatcgacgtc ggcattcagg
    24661 gcaaatagcg ttccggcgag tccaagtagc gagcggcgag aatcctggcc tctctctacc
    24721 gaggcaacgt ggggaatcgt acgtcccaga cctttgacta tctgccccaa tgggcctttc
    24781 agcgctgggt gtgggccgat ctccaccgtt gcgccgattc tcaggtcatc catgtcgagg
    24841 agcttggata cggcatcggt aaaccgtacg ggtgactcca gatttgcttt ccagtatgaa
    24901 gcagtcactt cctcgcgagg catggttgag cttttttgtg gcaccactga agaagcccaa
    24961 ggaatgttgg agtacctgga agtggtgtca ttgattccta ggctggcaag acgctgtaac
    25021 ccatcatcaa ctgcctgagc gtaatcgtga ccaaatgaca gcatgtggtg tgaatggtag
    25081 gcaagtcctc cggtgcgaag ctgtcggtta aagatagctt cttgggtgag ctggacgctc
    25141 agctgctcaa tggcatcagc gtcaccagac atggtgatgc tcgccggaga gttgatcgcc
    25201 gcgaccttga ctcttccctc cataccggcc tgccggacat actcggcacc ctggtctgct
    25261 ccaagcccga cagccaacat agcacccttt ttctggttga atgagaccat gtatccacgg
    25321 tagtaagcaa tggtgatggc ctctgcggct gtgatccgac cggcggcata cgctgcggcc
    25381 atttcgcccg atgaatgacc cacgacgcca gccgggcgga cagaccatga tgctagcagg
    25441 tcaacaagac ccatctgtag cgcggtgcat acagtttgag acacggcagg cttctggatg
    25501 agatccttgt cacagttccc acacagaatg tctacaagct tccatggagc gggctggggc
    25561 aacacagcca gcacggtgtc gaggtatgcg attgtatctc ggaacacagc gtactcaaac
    25621 agctccgccc ccatggctgg ccattgagca ccctgacccg tgaagacaaa accgacgttt
    25681 acccgttgag gcgaggcgaa cacctttggt ccgttgtcgg tgaccgatcc gacctgggtg
    25741 acctggtcct tgtcaacaat cgagaaggct cgttgcgaga atcgagagcg tttagctgcg
    25801 agagtgtagg ccacgtcggc taatgagtga tgaggaatgg atcgttgcag cgcctccatg
    25861 ttcgcaatca gagaagactg gttgtgcgcg gagaagggga gaaccaccat ctggcgagtg
    25921 gtggcatcgg cccgtctaac gagggtcgga gaatggagta taggacggtg cagctgggag
    25981 agtgcttctg gcttggtgcc gtgggtgcca ttagtgccat tggtaccatt aacagcatgc
    26041 ccgtttgtac cattggactg ctcaacttgc tcgtaaatga cgccaggctt cacatactcc
    26101 gggatgacat tgtggacgtg gtcgatgatg caatgtccgt tggtccctcc aaagcctgcc
    26161 gaagtaacac tggcacgctt aagtcggtct ttaggccagg gctctgtctt attgacgacg
    26221 cgagccttgg cctggtcaaa gtcgatgcgt ggattggggg tctggaaacc gagcgtcgcg
    26281 gggatctctc cggcctcgag agaagcgacc accttaagga tacctggcaa ggcgcacgca
    26341 ccttccagat ggcccacgtt agttttaaca gatccgacaa ccaggcgatc ttcatggaca
    26401 gtagaccgtg atggcccaaa cacattccca gctgccgtca cctcaattgg gtccccaacg
    26461 cgggtgcctg ttccgtggca ctcgagaagg gttgtttcgg agggatcgag atcccctgcg
    26521 ttcttgtagc tgttcaagtc agtattagaa ggtcatgcgt gaggtgcaaa gtgtgtaaca
    26581 tggatagagc tcacgcttct cgaatgacag tctcttgtgc ggggccactc gggttggtga
    26641 taccactcgt acgcccgttg gcgttgaccg cactgcctct gattagggcg cgaatcggag
    26701 acgcatcttg ggttgcaagc gagactgtct ttaggtagag tgctgcgaaa ccttcgccgc
    26761 gggcgtaccc gtctgcggag gcatcgaaag tgtggcttct ggaagaaggt gacagggctc
    26821 ccagcttgcc catagcaatg tggcagttgg ggtccataac ccagttggat ccggctacga
    26881 tggccgaatc gcaatcccca ttgcgcatag aggtaatagc caggtggagc gcatacatgg
    26941 ccgaggtgca tgcactgttg attagcagac tcggaccttt gaggttgaaa acgtagtgga
    27001 tgcggttggc cagcatgttg ggaaaggctc cagtagccga gtatttgccg ctatagtccc
    27061 aatcacgcgt ctgggacaca taattgtcga acgagatatc gccgacgaaa acgccgattc
    27121 ggctaccgga cacactgtcc catgtctccc ctgcattctc aaatgcttca tacgtcactt
    27181 cgagtagctt gcgttgcgag gcgtccatgg tttccgcttc gacatcggta attccgaaga
    27241 aagacgggtc aaaaagccgc gggtcctctt tcaagaggaa gccactgctg gctacagcag
    27301 tcccaggccg gtctgaattg gcatgataga agccttcggc tgaaaaacgc ggcgcggcaa
    27361 actccccgtg agcatccttc tggtcccgga ggaactccca caacgcagga atgtcctgaa
    27421 cacctcccgg taggcgacag cctattcatg ttaacaatgc ttgatttctc tccaaagccc
    27481 gatataatca actcacccat gccaacaatg gcaattggct cgcactcatt tgatcttggg
    27541 ggtgtcatga tggctcagta aggaatatgg gtatgagagt ggtaaagatg aagtatagag
    27601 atcgttcgtg ctttttgtcg aattcaatag agaagttgct gtatttgcca aatgaactgt
    27661 ctcgtccatg gcaacacagg ccctatatag caattcatcc tgttcttgaa tcctgactcc
    27721 tgcactatct acggtgaata gctgtagttg tcttctttct gatggtgtat ctgctgccat
    27781 gttcaccata cgtgcatgaa gctactgcac tcattaagcc ccgcgtcggc cgtttcgtgg
    27841 cagccttcac attcgggtat tccagttgat gaagacgccg tgtgctgtct acggacctcg
    27901 gccgaagacg ttggaggaac agacaagtcc tcagattcct tttcttggcg gctcgtgttg
    27961 atgctgatcg tgataagctg gacggaggag ggacgggcga aatcgcccga tgcgaccgat
    28021 ggatgtcggg gccgtgactt tcgtcagcac tactcagaag cgagacactt cgcatggatt
    28081 cgattccttc tctgttgcga gccgaagttt gctggcttct gtcattggca ataaatggaa
    28141 ggattgccta ccttcagcca cagtcccggg cgcctaagac tagacctctt cctcagaggt
    28201 cctttttggc ccccttcatc cttccccacc ttcctttccc cccagattga ggggatccca
    28261 agcaagccgg actgagaagc atgccatatt gggaaggtaa aaggtgccga gatgggatga
    28321 aaccagactg ttgataatta tggggttaac ggccctctga cgaagatcaa atcctcccca
    28381 tgctccaacc cactcgcacg gaccactgac ggtacgtagt acaaaaatgt gatatgcagt
    28441 acaatgagcg gctccaagtg ggtgttgttg agataagcgt ggcgatcctg ctggtcaacg
    28501 aattcattga aggttgcaga tgcagcttgt ctgatcttac aggttctgct ggagtctagt
    28561 ctacgttgaa cgtacttcac aggacgtgat agatcaagca tattaggcac agctccggga
    28621 tggcccgggt gccatgggaa caaatcagga gggttagttt cagtgtaatt gggatgcacg
    28681 ggatttaggc caccaataac accatcagaa acagccagag agccgcacgt ttcctgttga
    28741 tgagagtttg aagccgagta aaccgagtaa gcataaccaa gtagatccgg cgggttcttc
    28801 cgttccgcgt ggccgatctt atccggactg aagttaaatc catgcaggct cacggaccgt
    28861 ctggccgtct gaccccaaat gtctgacggt ctgacagtct gcctatctgg tcttctgtgt
    28921 ctgtctggct tgtccctccc aaatgctggt ggagacacgc ccccccacta ccccgaagcg
    28981 acctccaggc acagaaacag tcccacattg agatattccc cctcatccct ccactaaggt
    29041 ataattatct ggaagaagaa tagcttaatc ttgtgcgaca gctagacata acaagggcat
    29101 cgggcccgct ggtgttgtgt gagttgtcga ccagatggga ggagccgcaa tgcatcccac
    29161 cggccgaaag cgtcgggtca ccacctgtgt gccctgctac actaggaaac agagagtgcg
    29221 taaacatcgc taatcctaca ctgggcagct gaaagcttga gtcctaatgc gaactaaaaa
    29281 aaaaattagt gcaaccgcca gtacccgtgc aaccattgca cccgacgtcg acggccggag
    29341 gaatgtgtct accagtccat cattactgga gacccctcca acactttcct cttggagcca
    29401 gcgagagacc ctgagcccca ggaaccaccc aatgtccagt taccaaatgg atcttccaag
    29461 gcctcgcctg ccgaggcaca gaatagcgcg tctaattcac actcagctct ggctaaatcc
    29521 tttggctact tcgagcacag tgactccaat accatggctc tgctcaaaaa agtgagaagc
    29581 acacatgcaa ctgtggatcc atcctcttga catatggcta atctcaaacg gcatagtggg
    29641 atctggacag tgaaggggac acagatcaaa gcacccaggg cctgtcaact gcggtgctag
    29701 agacagtcaa acaagtcctg gaaaaaattc ctccccgtcc catcctagat ttcctgatgc
    29761 agtatttcgt cgatgaattg aactggtagg tcccttgtta gtgatcatat tagattcatg
    29821 gtcaactgat gccccatgga acaggatgaa acagatcatc cacccaccca gctttctgac
    29881 acagtatcag cattggtgga ctaaggagtg gcccctgtct gtggatgaca ttgagtttgc
    29941 cgctctggta cttcggattg gtgcctactc ggcgcaattc ctgccttctc cgacgcacac
    30001 ccttgatcgg atccgggggc agtcactctc agacatacgt gacacctgca gtcatctcgg
    30061 tggtgagctt gccagagcct gtctgtctct aaactggaaa gggtctctgg tccgggtcca
    30121 gcacatttta tttgccgctt tcagatcctc ttgtgaaggg aggactgata aattttggga
    30181 aggcatcgcc tctgcttgta gtgcggcgca gaaggcgggg attcacacag tggctccagt
    30241 gccgggggaa gatagttctc aagtattaga aaaggagatg cgccggagga cattatgtgg
    30301 gctgtatgtt ctggacaggt gcgtatgcca tgctcttggc actgcaacct tgcgctgacg
    30361 tggccggatc aataagccat ctcgcccgac agcttgaccg ggtccctttt ctccctgata
    30421 accttgtcct tgagacttta ccccgattac gtcttgcccc gtttattggc gacttggctg
    30481 cgtctgcaga tgcacctgaa gacttcaccg agcgtctcat gcaagtccgg ctgggcagat
    30541 tctggagaag cttcggttcc agacggaacc taccgtacga ccctactcac ggcgaacagc
    30601 ggtatgagcg attctgcgca gagtatatcc ctaccctacc accagcctat gcactgaatc
    30661 cagatcggag gtgggacggc caacttccta aattacccat gcagagacag ctgctctaca
    30721 ttgccatatt cgattcagtc tgttggaatt ttcgtccttt actgttgctg aaaccaggcc
    30781 aagtcaccag tctaccccct tataagcaag ttcttctcca atcgcagaag cagaagctgg
    30841 ctctggccgc tctggaagag ctggatgccg tcacagctct gcatatcatg tttggaggct
    30901 cccacacgcg tttcagcgcc atcatattca acacgtttga agccgccgtt gttcttctga
    30961 tactttgtac gcagaaagac tttccatttg atcaaggcga ggatcatccc gatattctcg
    31021 gcttaagagt ggccactctg actcggcccc gggcaatgcg ggcggttgag aaagccctgg
    31081 gacgtcttca aatgttagct gaggtcagcg aaatggctgc ctctggggca caggttgtga
    31141 cgcagctttt tgcgaaggct gccaggatgg agcattccct cgagccatat acacctaatg
    31201 agtcaagccg gagctcttca tctccagcca tcctttcgaa cttcctcaac ctagaagacg
    31261 gctctggact ctggatgtct tcagaggatc cgaccttgat gccagacatg ttatccacaa
    31321 tagcgcacgg tgactcatac tcaatgctgc aatttccctc tctagacctc acgtcttgga
    31381 atggcaattt ccactcgtaa agtggaatta ttttcctcca agcagagtca ggcttgtaat
    31441 cactgccggc gaggatatgg acacccgttc aaggctggcg ttcgtgattc gtagcaggtc
    31501 ttccttcact tggattttcc ggtgaagcat caacccgata agcagtaaat agttgttagc
    31561 ggaatataca gttcgatgga ctgctagtgc ttacattaac ggattcggaa ctcctgcacc
    31621 tgccatttgt agatgtggag ggtggccact gtgtctacgc aaccatggag aaggagatat
    31681 tcacgtagtc tgactacatt ccaggtcgaa cctgctcgct tccgtggggt gaattaacgg
    31741 gtagaggtgc gtccgacata atccccgata ttcgtcggcc gacatatttc ggacgagctt
    31801 tcaacacagc ccgccacccg aaacatcact cccttcttac attggcactc gactgcaagc
    31861 gtggctgaga aggaagcggg gctttccaaa tcagtatcta accttcgatg atggccgaaa
    31921 ggaatatacg gttatgatcc atgaaccaaa gaacatcggc ctcgttgttg gttattccga
    31981 agacatgatt agtattagca ttaagggcct atacttggcc tcaaagatcc atgaatattt
    32041 agctcagaac agccgtccgg aaggtaaatt ggatattgcc taccttgtcc aaatcctatt
    32101 ggaaatacaa aattcatcgg tcgcatgaca taatggcgcc ttcttacatt gccagctttg
    32161 ttgagctttt tcatggatac cctgctgtct tctcgattac gatttgcctg gtggggttat
    32221 acgtccttta tcgatggctt ctcccgagcc cattaccagg aattccttac aacaagcagg
    32281 ccgctacatc aattttgggc gacgtgcctg ctctgagggg cgatcctgcc ggactggcta
    32341 agtggtgcag caagcagctt gaggagcatg ggtctccgat atgccaggcg ctgatgggcc
    32401 cgctctccaa gccggtggtc cttgtggctg acgtcggcca gacccgcgag ctgctgatgg
    32461 gacgaagtga cttcgaccga tcgtcttaca ttatcgatcg gttcccgtta tttggagagt
    32521 tccaccttaa catgaagact ggggactcct ggagaacctc ccgcagctgg ttgaaagacc
    32581 ttctagctcc gcactatctg caccagaccg tgggtcccat catccactct tcggtgctca
    32641 accttatcca tctttgggaa tccaaagccc gggtagcaaa tggaaggcca ttcagtatgc
    32701 tggccgacct gaaaacccta gctcttgatg ttatcgtgcg cttccacttc ggacaagact
    32761 tccaggactc ggctctgcgt aggcaaattg agtttgtcga gcagctggac aactctcagt
    32821 taggggttgg gaagcacacc gacgtcatct ttcctcaggc ctcgttgcac ccattccaac
    32881 agggtttaac cgatgtgggt gaccggatgg ctgccatcta cacgactaaa tggcctccct
    32941 ccatcgtgtc ctggtgggca cggtacatgt ccccatatta ccggaagttc ttcgtcggca
    33001 aagatcgctt tatccgcaag catattaacc tagcactgca gcgcttcggc aacgacgaag
    33061 aggctaagac tggtattgac tatatggtgt atagagagca gaagtcatct cgcaaggccg
    33121 accggcagcc tatgtatggc aaacagatca tgattgacga ggtgggtaaa cagcttcttt
    33181 cggcctctga aatctctact aagacaccgg gtcattgcat ctaggcatac ggaaatctca
    33241 ttgccggcca acacacaacc agtgcggcgc tagtatggat tctcaagcta ctggctgagc
    33301 atcctgccgt tcagacaagg cttcgcgacg agctgcagac agtatgcgcg gccgcagtcc
    33361 aagagggtcg cctacccact gcagctgaga tcatccaatt ccgactcccg tatttggacg
    33421 cagtattgga ggagaccttg cggcttcgcg ctgccatgct tgttcctcgc gacgctaccc
    33481 gtgacacaga gcttctgggc cgccggatcc cgaaaggcac ggtcgtcctt ctcgtctgtc
    33541 agggaccgga ctactcctct tcgccatcct ccctgtactg gagtgacgtg aagacgaccc
    33601 ggaagtaccc aggtggtggt aaccctgatc ttgaggcatt tgatccggag cgttggctag
    33661 tccagaatga gcgcggtgaa ctcgagtttg atggctcgtc gtacccgcag ttggcgttcg
    33721 ggctgggcat tcgggcttgc tgggggcggc gactggctca gctagagatg aggatcatga
    33781 ctgtcatgat gacttggaag tttgattttc tcgatgtacc tgaggcattg gctggtcatg
    33841 aggcaaccta cgacatctcc taccgcgcca agaagggata tttgcgtctg agatcccggt
    33901 aagcgcataa caagcaggcg ctgcaacccg aggccaatgt ttctgtaccc agcgcactta
    33961 gtttgctcag gatatttgaa atgcaattta aattggctac tcgtattgtc cagtaatgat
    34021 gagagaaaat agtacgacat tagtatacat gttccagacc ctgatcatcg aaacgtagcc
    34081 ctgtgtcgac ctagcaggta atttttcttc ttcttgctgt gtgtttagcc acaacaaaat
    34141 ccccttcttt tcctttctgt taggttcaga tcaaccccaa tgaaaggctt ctaagcttat
    34201 aagcaaatcg ctacctacgt ttcgtggatg ggcgccaccc gagagctgta tccagtgtga
    34261 atccttcggg ccggtcgacg atctgcattt tgccatcggg caggattttg gcaatagtcc
    34321 atgagttttg aatttgcatt ggagccagtg cgtgctccgg ttgttggttg gggtgatctc
    34381 ggatgcattg tgctctttgt cgggtgagtg cgtgggccat tctatcttcg gccgacgaat
    34441 ttcgggtgag cgacgtgttt gttatatgat gatcccccgg cctcccacgg ggatagacaa
    34501 tgctaaactc ctaatcccgc catcgtggaa gcactagagc ttcgttttta gagactattt
    34561 gtcctgcagt gtccctggcg tggttaatcc acgacgtggt ccgccggtca taacggacat
    34621 aaggagaagc aatgggtgat ctgccctgtc tcgacactat acatatgcgc gatcctcccc
    34681 agccgctcag tcctcccaac gagaaacaat agccctctcg ggttcgccaa aatggaagct
    34741 gcagcgcatt cactgccctc gagtcaggaa tcagacttcg ctgtgaataa tcatctccct
    34801 catcgcgaag agtccgatga gaaaggacat gacgccgacg ccagtgccac cgatgatgat
    34861 gtccgcaaga ttaccggttt ccgatggttt ctgatttgcg ctgctctgta tctctctgct
    34921 ctgatgtatg gacttgatac aaccatcgct gcggatgtgc agggcgccgt gattgagaga
    34981 ttcggggacg tgtcgcaact tgcatggatt ggagccggtt tcccactcgg ttcagttgcc
    35041 gtgattctcc cctacgggtt tctctatacc gtcatgaata tgaagtggct ctacattgct
    35101 ggaatcgtgt tattccaagg tggttctgct ctctgtggtg gtgctccaaa tatgaacgcc
    35161 cttattgtcg gccgtgtgat tgcaggcgct ggaggtacag gaatctatct cggtggactt
    35221 aaccatttct ctgccatgac cacccgcaac gagcgcggca cctatcttac aggaaccgga
    35281 tttgtctggg gcgtgggtgc catcctgggt cccgtcgtgg gaggcggatt ctccgactcc
    35341 tccgccacct ggcgctgggg tttttacctg aacctggtaa tcggcgccat cacagccccc
    35401 gtgtacctct tctacctccc cgccattcac cccggcgcgg gccaatctct tcgcaaacgc
    35461 ttaacgcgac tcgactatct gggattcgtc ctcagcgcgg caatgtgggt gaccttcgca
    35521 cttggcttca tctctgcagg aggcatctgg gcgtgggact ccggcgccac catcgcgcta
    35581 atcgtgctct tcggcgtcct attcatcctt tacgccctcc aacaatactt atgcatcttc
    35641 actacgcccc aaacgcgctc cttccccggc catctcctcc gctcccgcac ccaaatcctc
    35701 ctctacatca caacgacctg cgccaacacc gccatgttct tcacgacctt ctacatccca
    35761 atctacttcc agttcacgcg caacgactcc tccctaatgg ctgccgtgcg ccttctcccc
    35821 tacctcctcg taacgatcac catcaacctc gccatcggct ggctcctccc aaaagccaaa
    35881 tattacatgc cgctgtgcct catctcaggc atcctcctca ccctcgccag cgccctcttt
    35941 gtcggatacc tctcaccctc taccccggca ggacagatct acggtttcac gatcctcatg
    36001 gctgtcggca ccggcatgac catgcagctg gggtatgcgg tagctagtct caaggtgcct
    36061 cccgaggata tcttcagcgc gatcaatttg cagaatgtgg cgcagattgg agctacagtt
    36121 atctgtcttg tggtggcaag tcaggtgttt cagtctactg cagtaaagaa tctgaaaggg
    36181 gtgttggatg ggaggggata tagtgaggcg gagatacgga atgctgtagc gggtgtgcag
    36241 agtacgttgt tgaagagctt gagtggggag ttgagggatc gggctatcaa ggctattacg
    36301 gatgcgatgg ccagggcgtt tattattccg ttggtggccg gagcggtggg ggtggtgagt
    36361 tcgctgggga tgaggaggga gaggttgttt gggtagatat cttgtccggg gtggaggtat
    36421 agaggaaaat aaagtgatgc tagggtataa attgagtgaa tatggtatgg ctcaaatatg
    36481 aaaggtatga gcgggaaaga agatatatca cgctaattta cacgcaaatg cttcatatta
    36541 gccacaatgt acgtcgtatt tttcgctttt tcgtctctgc ggggcggatc aaagagaagg
    36601 attaataaat cccctcacgg aagagcattg gcattagcag caatacaatt gctacctctc
    36661 catatgttcc gcagatgaaa gccccccaat taagcgtagg ctgaattgac gagtaataca
    36721 cctggaaaca ggcgtggcca actgcccaca gcaacaaggt tttccaccgt tgcatccttt
    36781 gagatatcaa taagtgaaga aacacaattg gtttcacgaa gagcagcaac atatttagcg
    36841 ggacgtcctt cctgaagtct tcctctcgaa gtaaaatata gaagataagc ccatttagtg
    36901 ggataagaaa aattggcccg ctcaaaaact gcgtcagctt tatatgtgag acataagccg
    36961 gagcgttact atggatagac aatcgaaaca tcttgctggc catgacaaac tgctggttgc
    37021 gaaacatgat aagcccgcgc tggtgataca ccttggacat catatcttgc acttccctgt
    37081 tcgactgatc ctgttgcata tcaagctttt ccattaggag acagtagagg tcctgggatt
    37141 tggccagatt tcgcttttcc tcatatggct ggcacaggaa atcaagatag caagtataga
    37201 tgggtgaggc ccgggtactc caaatcatat ataaatcggc aagtcgtaac tgcgctttca
    37261 gatcaaagag gctgttgtat ttatccttgc cgctagaaag atagatttcc aggcatcggt
    37321 ctgcatgagg aagaagacgg tttctatcag ggagttccag tgagaaaaaa ttgaatttgg
    37381 tgaccagatc caactggtaa gtactgatct tcaaaactgc aagctgcgtt agcaggtcaa
    37441 tatctgacac gaagcagtcc tcgtattgaa gccaggcatg aatgcatttt tgaaggctat
    37501 agccccgacc ctgctgagaa tttcctgctg cgacaggccc tggttcgacc catccatacc
    37561 tacttagcac agccattgct gtatcgaaca ctaaggggtc ggacgctgat tctggtcgag
    37621 cactctggaa gaggccatac cagatatcgt tactattaaa agctatccac tgcttaagca
    37681 gtacggcggc atgtctatgc tggcgcataa tctggtttag tgtgattttc cacgttgtat
    37741 gcattgactt ttgttcaagc gaagattgct gcggcgatag ttgttgtaac tgcagccaag
    37801 attctttata taatttgaga tactcgcggc aagttatcac actctgtttg agataggccc
    37861 cagcagacac gatggccagt ggcagcccat ctagctgagt taatagttct gcgatgtagg
    37921 ggtctaagta gtaccagtca gctgttaata gaaatgcata gcagggacga cgggttactt
    37981 gccatctcgt agattcggtc gtccgcacac atgagtcaga agatcgaggc cgtcatcaat
    38041 tgctgccagc tttcttactt gaatctgatc acctattcca atatcataac ttctcattgt
    38101 aataatgata tgaccctgct tgcttggagg cagtctcatt ttcatgattt cggctttgtc
    38161 aaaaccttcg accataggaa ggtcgaagcc atcgtatatg agtaaccacc gattgtttga
    38221 agggcgactc agccactcat tgactgatcc aaccaattga atctgatcac cttccttcaa
    38281 ggcctttctc aaagactggt cacctggatg atcatgtatg atccgcattg ccgcttgtgt
    38341 atagctggaa tataacttgt caagactgct accatcaatc cagaagacag atgaatactt
    38401 ttgccgatgg cgcatgatgt acataatcga gagttcggtt ttcccaattc cacccattcc
    38461 atatagggtg acaatgcctc gaaatctgtc tgatagaaga ctcttcgtta tcattgcaag
    38521 ctctgcctcc cggcccacag aaatggcagc ctgtggcatt tcgattgtgt cgaagcgaac
    38581 atcgaacgaa tcgccttcat taacatcagt aatagctctc tgggtataaa gtacaccatg
    38641 cttgggcccc acgtactact attcttcgaa ccaggtgcct gtatcagcgt agacgcctca
    38701 ctccgatgga caggaatctt cgacaatagc aatttcgcat aggccgcggc tgtcaaagcc
    38761 gcgaacccct gccactcttt cttcttgtgg gagtcagaat agtcacaaat ccctctgatc
    38821 acgaggcacg gaaggtaatc catgatcccc gccgcctcca tttcaaaaca caagatcccc
    38881 tgtgttgtct gcgcaatgcg atcgcgcgtg aggccatgct tcatgacttg attgcccgac
    38941 gcaatgttgc cataatgtac gaccggtgtg catgagcgtc gaggcttgcg tctcacccgt
    39001 cgttctgggt cacactcagc acaggatgcg aagcgaggat catggtcata ggaggcatcg
    39061 aagagccaat catgttcggc acccggatac cgaaacacgg atggatcttt ggcagccctt
    39121 agagaatccg cgataatctt ctcataggta ccaatgtcgc tgcctccagc cagacgatct
    39181 gcttccagcg acgacaacgc tgataggaga actatcggcg gcttgttgag tgtcccggtc
    39241 tgctcaaagc gacctgaagc aacggtcttg ccataatcgt actggatcac tccgggaagg
    39301 ccagcagtcg gcttacttac gaccacatct cccagtctga catcgacagc agacgggact
    39361 cctccgccaa tcccgaccat gaggccaaag cggatggacc gaaaggtgaa tagcatctgc
    39421 tcaactaccg cagtcgccga cgtagttccg taaatcccga atggaagaca tgtaatcacc
    39481 actttatgtc cggaaatcct tccaagcacg taggtgttgt gatgctgctt aggtaaatgt
    39541 agacttggat attcttcgtc gaggacggct ttagctgcgg tcatctccag tggtagggca
    39601 cagatccagc ccacggcaaa ctcatcgtaa gaaggtacgt catttcccga catcgtgagg
    39661 tgccttcacc gactagagag aatctgctct tgtttagtcg agtagcactt ccggggatct
    39721 ctaagttgat gagtagaagg caccaagtac acaaggctga cgtgctgcgc aggatgacta
    39781 ctaccagttg gttgagttcg gcgcgctaaa agctgacgac gcacaactct gccttaggct
    39841 acgaggccgc ccaaattata cccatgtacc aaaagcccat gtagaattta tatctttatg
    39901 tactcttaga gcctttgatt catctactga ttcataatac ctagcatcaa ttgtatagct
    39961 tagtgcaact atagctaaag tcttgccagg gcgaagcata gaacggatga gagccaagta
    40021 agaggtcacg aagaatctac ttatgactcg ggcgaagtag taaggtcaac ctgctagact
    40081 gaaacccgat attgtttatt cataattcag atcagtatct tggatacaat gctaaaggta
    40141 ttatttcaaa gcccgtcata tcgtgtctta tgctaacagc ggcggtctgg gtaatcgcct
    40201 gagcttaatc tcagttggag cgcttccaag tctggaatta tttagagacc ttgagaattc
    40261 gaaccatgtc aatgtttaca aacttacaga tgcattacgt cttagtttga aagagctctg
    40321 aatctttccc accgattaaa gctctgcctg gatccgactc aggagagcgg cgtgaagatc
    40381 ttatccaata ccgctatgtc gcagcctaaa tcagcacagc cgacccaacg attatgctaa
    40441 ccaacaagaa cttctcggaa tcgtttctat aggataatga gtctttaagt gacagtcact
    40501 ttcattgaat tggccggatg gtgtagttgg ttatcacgta tcgttaacac cgataaggtc
    40561 ctgggatcga gccccagtct ggtcattctt ttttgccctt ttgttttttc ggcagcgtac
    40621 aaccacccca tcagtcacaa cgaacgtaga cacctttagt tttttatttt tttatttttt
    40681 ttttttttca aatgaaactt ctcctgccaa accactatgt tctacacaag aactcaagac
    40741 agcctactac ttctaatcag tgttcgcaat ggaggggcgc agactttgaa ccgcttgact
    40801 attttcagtt tatatatcgt gttccattcg cgagccttaa catactatct atgcaagaca
    40861 atcataaaca gcccgcacat aagccgccgt cctatccgaa cccaacgtgc cttgtcccat
    40921 cttattcatc acataggcaa tcgtcatccg tttctccagg tccataacaa caactgaacc
    40981 tccccagccc gtccaaaaag caatgcgacc gtcgggcaac caaggaaaag tctccgggac
    41041 gggcaaccca acaccaagac cccaacgcaa atgatacatc aagaccaaat ctggcccact
    41101 tatttgctcc tccagcatgc ggtcaatagt ttcaggcgag agatactgct ttccatccac
    41161 cgtgcctcca agcgaaatga ccgacgcaat gcgcgcaatg cctcgggcat tagagaatcc
    41221 attcgtggca ccaatcaacg ccttcctaaa cccaggactc atactttctt ccgccggtat
    41281 aggcagactg gcaaagctct tgaacataac actctgcggg tcaacgccgt cgagactcag
    41341 tggcggcggc ggggaaacgt ctgctgttcg tggccagtcc ttctctggga ccccgagctg
    41401 gaagtccgca gccagaggac tggcaagctc gtcgcggatg aactcatcca acggttttcc
    41461 ggttacacga tgcaccagct cgccgagtaa gtggccctgg ttggttacgt ggtagccgga
    41521 gtgttcgccg ggcgtccacc agggggcctg tcgggctagt ttatcggctc ctcttttcgc
    41581 atcgtatatg tcgtctaagg tgttgggaag ctcccaggag gatactccag aggtgtgact
    41641 gaggatctgg gacacaagga tattctcctt gccgttcgca gcgaactcgg gccagtattt
    41701 ggagaccttc tcatttgggt ctaagaggcc acggtcgatg agaatgttgg ttgcgatggc
    41761 ggtaattact ttggaaacgg accataccac ggttagtgtg tccttttccc atggcttggt
    41821 tctcgctggg tctgcgtggc cgccccagag atcgacgacg ttttgaccgt cgatgttgac
    41881 acagatggat gctcctagct cttcttcatt gttgatcaat tgctgtagga gatcgcgcac
    41941 cccggtgaag gccggatcgc agtgaccgtt gattgtggtc attgcggagg ggcaggtgga
    42001 aggacagact gaatctagga atttgaaacc tggagaagag cagggatcat ggctcgggtg
    42061 atccggcata aatagagtga caactcactg gggtctggaa aggcccccac gctaagtaga
    42121 actggcgcag tgtcagctct acacttatgg attagttgat ctctactaag tactaacgtc
    42181 tactagttag tacggccggt ccccacagcg cctgtgtcat agggaatcat cagctgctgt
    42241 gatggtcagg gaaggtcagg gaagaccata cctgtaatct tatcaatatt gagttcgttt
    42301 ctgatacagc gagatgaaaa gactagactc cgaaggagat gtcacgggga cagactcgag
    42361 tgaagtgtct accagaagga gactcattta acctacctca acagactgac tcaactccgc
    42421 acttcatgcc cctcttggtc gcatatctgc ccatctcata cctacggaaa aaattaaaat
    42481 tatagccaat gcattagaca agttttatct agacacttcc tagctgttgt ctctggtttg
    42541 aatgggtggc cagtgcgcga gagggaccgg cgggaagcca caagcgatcg gcatcggcct
    42601 taatgcttag tgctgttgtt atactaggtt gtatgtgcga attatgtggt atatactggt
    42661 actctgggtg ttgctttgct tgtttagata tggagaatag aaaaaaggtt ttcatatagg
    42721 atttaaatta gttataatct tgttctggtc ttagtagtat aggagttttc ccttctcaca
    42781 cctcctaata tgaggattta tatcatacat gatgcatgtc aggtcaattg caaaccaaag
    42841 cgactgccct tcatgcatga aaactgagcc cgtacccaca ctgaccctag caactttttc
    42901 cttatcggta atatgacctt catttctttc tttccatatg cggtcataaa ttcgtgcacg
    42961 tatcacttcc tcactggtcg tcagtgcgat gatggatgca ttgacaagca atgcatgatc
    43021 ggttcatatc cacgacagcg acctcaccat ttgccgaatc tcttcacaag tacgatgcca
    43081 ttcccccaca aatatcaaca gtctcgtaat tagttccgaa tcctctcagc tccggaatga
    43141 ttcggtagta gaagttagcc gcatgatcag tctcagcaaa accgatgaag tcatccatct
    43201 tgtgattggc attgtctgca tagacagccc atgtagcagc tcctgccagt gccatagact
    43261 tttgatgggc ttgagtgagc tgtgatctac ccctggtagt gaacgcaatc ttaaaccccg
    43321 ggttgtcaaa ccgcttcctc aaatcaagtc cttcagtgtc attagcacca ggaacccctc
    43381 ctgcaagagg aagttgaaga acggtgtcac cattttcata gtgattggcg atgatatcgt
    43441 gcttcggaga gttattatgg gcgaaaccag taatctgaat tctgtggatc ggtaaaggct
    43501 gatcctggcg tctaaccaag ggaagagtat ttgaggtatt cgagagagga gtgagataat
    43561 cataggagat atctccacta cttgacagca tagtctccca cagctggaaa taatcctggg
    43621 agacatcgac gtcacgctta cccggtagac cttcgggaat ggctccagag taatgggcgg
    43681 cagcaacata ggccaagagg agaccgtctg aaataatata agatatttcc tcacatctac
    43741 tgccaccggc atattcacag acttgtcgag caagacgtga gcccatcacg atatagacga
    43801 ccctagaaat tattagtccc ttgaggatta ttgttgatcg agaggagagc atgcgccata
    43861 cgtaaatttg ctggtaccaa tagaacgaat cgttcgatta agtatctcac agactctagt
    43921 atcccgctgc tctagaatcg ccagcagctc gtcagccggg ttaggagatc ggatttcaag
    43981 accggtgtct gaaggaagtt cagcaacatc cactattgga attggtgtcg ctaaagtgac
    44041 ctggcttgta gccagaagag agaagaggaa ggttgagagt ttcatgctga tgctttaaga
    44101 tggttgtgcc acttaggaaa tcatttttgg ggggttcgct acgccatatt tatagccgta
    44161 tgttggtgtt gagcgattct ccttagaaca tacaagactt tgaattgtac ggtttgcaca
    44221 tgagacataa tataatggct acccacataa aaatgagcta ttgaaataat ggtgctttta
    44281 gtatgagagg aaccatgggt ctccgatgtg gagttgggga acagttgata gccggcctac
    44341 gaacccttgc aaagctagtg gggttagcgc tagccttcgt acataaatac ctcgaagtag
    44401 ccaccggact tctaatcatc taccattagg tacctgggtg caactgttcc acacaatata
    44461 tccttgcctc cagcggtgct aatattttct actgtcgaat aaaacaaaat gggtaccaat
    44521 gaaaaagcca cgacgtcaat ttctcactcc tcctcttcgg caacaccttc gcgaaccgtt
    44581 actgttcttc ggaatatcgt gcaaagtccg tggacgtaag tatgatttct tagattaatg
    44641 ctttccaaat ttttgaagct aatcttttag cctaccttat atcgcaatgg ttactccact
    44701 tgtgcgaagt atctggaatt acatgggatg gagtaacgga ggagaggtgg ccctgtcgct
    44761 gagtcacgga ctgttaattt tgtacttcat tatatcacag tatgtccgca ggtacgaatg
    44821 acagattact atactcaata aaaagtttca taaacctagc tatatcagct gtaccggaaa
    44881 agaacttcag catctgctgt gtgagatcct ttcccgactg agtgtgctga aaatcagcaa
    44941 tacagggttc gttgagacaa ataccccaag gtttacgtta attgttatcg ctacctgccc
    45001 aaggcaggta gaatggccta aatctaccca tcctccaccc agatggtcct gcctcggtgc
    45061 tttccaaggg gaaatgcgag aaagacacct ggcgggaaat tccgaaactg ctatgttcta
    45121 ttattttgcc ccacatcgcg tagggttggt gggtgaacgt gccatggtca tactcaaagt
    45181 tagcatgcgc caatgttcac atcaattatg aggctttccc tatactgcta atgctgtctg
    45241 agggtctgta atgtatcagc tccacttttg gaccgcccta cacgatatgg tctttcctta
    45301 caatagttat cgatgcttga taaccgaaca cgcgctaaac aaaacccgcg attaaatcca
    45361 ccttccgagt ttagcaaacg cgccacaagc cgttcggtta agcgccttta ggacataagg
    45421 ttacatgacc acagaacgat aagcaagatt caaaatcagt atgtacagcc acaaaacaat
    45481 actgcgccgt atcaaatcgg gcatatccta cggacatttc gtgagcccag tcgggataat
    45541 agaaagaact gccttaaaaa ggacaccttt aagacaagta gaatatctta tcggaagtag
    45601 agcattttag tcggtccata attgcgatgg gtctctattc tactgtttgg tgccacctga
    45661 ctctccgtat atccttgctt tatccggtcc tatactcgga tggctctgga atatagtggt
    45721 ttcctttgta gtggattcct accctccacg gagctcatga tcttgagttg gtccctcctc
    45781 tctagtgggt ccctactatt cggtcggttc ctagtggata ccccctctcg tctgataatg
    45841 gtccgaacaa gtgactgccc taccaagcag tccaacctca cttgtgatcg attattctca
    45901 cctattgtct ttatatatca gctccgtccg taaggacttg tgtcccgttg catctgtccg
    45961 agaggctgtg aaccaggaca tggaagcagg aaggtgcata cgctttcaca agcctgattc
    46021 tgacttgaga ctgtggtctt cagaccaact aagacatgag acttctttgc caagacttaa
    46081 tcagagaaaa acattttcta atacagctga tccactaata acacactccc ttcacaataa
    46141 taagtctcat gtccaccatc attggtacca gttgaaatca gtcaaggccc acctgcagga
    46201 ccactcttgt cccagtaatt ctgcccctgg ctgcggcatg tgccaataac gcaataaaat
    46261 ccaccgcctt tgttgttctg gtttggggag aacatgacga agccggcatc attattgggg
    46321 ttgaaccccg tgcacacgtt gtaaagtccg ttttgggcag tgtacgcagt atgagcggtg
    46381 ttgtaccaga tacagacggt ctgatgggag ctagcagtgc attgatagtc aagcccggtt
    46441 gtccagctcg cttgcaccgc aaagccgcca gagatccatt gtgatgcatc tgcagtagcc
    46501 gtccatccaa ctgtatacga ctttgactga gatgcgccaa cagtgcaata gtgtgcgctc
    46561 ccgcaatcca gattctcctg ttcgtcgcac atcagtcgct agcaccagac caaaggaaag
    46621 tgcattatcg gctcacgccc aactgtttcc gccaatagtt ctgatgggga tcgccgtctc
    46681 caactttcct tagcgggtga ccacattctg cacgcgccgg tttgtcgctg ctccaaattt
    46741 ctcatagaca cagcgtcagt ggaatttgct tcacgacgag gcattggaaa agtgtccata
    46801 acgtggacag tctccgctgc tcgctgtaaa gttatgtcga cttgatcgct gaaacaaggg
    46861 gatatgtcgc ccactttaac tgggttcaat tggacggtgc tgggcaaagg aacgccatcg
    46921 cacaccatga gtgactcatt atcattgtac attctgtaaa aagtgatacc accagaatac
    46981 tggggattct catgaacgct gaaggtggaa gtcccggcag tgatattgcc atcgccgtta
    47041 gacccaacat ctgcgacgat accgaagtcg gcaaacactc cggttgtcaa gacatttgag
    47101 caggcagagc cgatgatatt tcagtagagc tatctctcac cacaatctgc ttggatgtga
    47161 tcttatgttg ttgcactgtt actcgaacgt acctgaggtc ttcccggatg tgaagcgatg
    47221 gcgccgttaa ggcagttgca gcaagtgtca agaaagacat caatatcatc atcatggaat
    47281 cgtgggttat gtgtttcaag gtccctgaga ttcccaagtg catcttgccg ctgtagcgac
    47341 ccttatactg tcacttctcg cacaacgcgt tattctcctt tttaaaaagc tagcgaatag
    47401 gtgttccggt ctcagttgac aaaaggacga cattagtgac gttacatcgc ggcccatgta
    47461 gttgttaggt cattgtcgca tgagtctgat cccaatgcac tagcaaggat accagggaat
    47521 gcattaccaa ctcaaggggc cgtgcgac
//
