LOCUS       KZ851913.1             21606 bp    DNA     linear   PLN 20-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   KZ851913
VERSION     KZ851913.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 07:38:58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 276279
            Orig. end    :: 297885
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21606
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[<286279:286347](+),
                     [286434:287494](+), [287546:287729](+),
                     [287777:287885](+)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(<10001..10068,10156..11215,11268..11450,11499..11606)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..21606
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21606
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     CDS             join(<1954..1963,2070..4174)
                     /codon_start=1
                     /locus_tag="M747DRAFT_322964"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_322964-T1"
                     /transl_table=1
                     /translation="MRKGNSYWDRNPSRDQVSCGERGHWRLAGLGGGMFCTQTLIILLS
                     SQVLLTTNSTHRIVIPPGFLLASFFPSLPASAVSSPHLDGQEPAVDWLVPSSCLQILEH
                     CRNAMSRSPFRPSTPATMNAADKQNNGHLAKPLTPALSAAFHRSQKSPLTPRLATPGGY
                     RTPKRLAASEHPSSAPSKRDPEPSSSSLLSANVTPRSGSRNSRRDGAVSSPNNNNTPTN
                     GQQSPQVTWTQPHVGQLSNTGRLRTERSPVRGAMLEPSRTTRARTVTMESNHLSRPNSA
                     SDNSAGAPMFFHASDARSTISEQEPRPKLQTKTSGTTFIYANGAQERQSPVSEVGGTYK
                     RRSIGLTRSVVSAKPSASPRLRPARVDSNPRLSDGPSVVGSQDDSFEAGSQAHSPPMSS
                     VSARPIPAVRHVKSSSLDSGHSGLSPPQKEGLRPSPLIISPSEPKIDASTIASEPLPGL
                     RPRVFSNGSIASVDTHNSGMQSPSKSESGQANGALNARTERKIMDLEISNSSLLAINRT
                     LEREMRKQNAELRRYRRLSRSGRLSMATSSRSVSGALSIPPEVEEASEHSSVRSPEELS
                     DFSDEDSLEDGVLSPDSQADQDSQHRARDEKRFLIDLAKHQELLADSQRLNQSLKRCLG
                     WTEELIREGQRALEYNVHVNDVQLGGRVLTPEELNELNELNELHEQQELEDISRPSSRS
                     DSEPPSEDGS"
     mRNA            join(<1954..1963,2070..4424)
                     /locus_tag="M747DRAFT_322964"
                     /product="hypothetical protein"
     gene            <1954..4424
                     /locus_tag="M747DRAFT_322964"
     mRNA            complement(join(4346..5338,5400..5526,5617..6211))
                     /locus_tag="M747DRAFT_295447"
                     /product="phytase"
     gene            complement(4346..6211)
                     /locus_tag="M747DRAFT_295447"
     CDS             complement(join(4474..5338,5400..5526,5617..6181))
                     /codon_start=1
                     /db_xref="InterPro:IPR000560"
                     /db_xref="InterPro:IPR016274"
                     /db_xref="InterPro:IPR029033"
                     /db_xref="PFAM:PF00328"
                     /locus_tag="M747DRAFT_295447"
                     /note="SECRETED:SignalP(1-20); EggNog:ENOG41; GO_function:
                     GO:0016791 - phosphatase activity [Evidence IEA]"
                     /product="phytase"
                     /protein_id="ncbi_M747DRAFT_295447-T1"
                     /transl_table=1
                     /translation="MILLSPLTTALLCLLTLTTATNTTTTPFNLHSTWGNLSPYTSSPG
                     FGIPPGTPKTCQLTQAHILHRHAQRYPTSYLLDADSMESFAQKLKNYTQAHPNSTLATG
                     PLSFLNNWRYLMGTEALLPTGAATEATSGAFHWSRYGRVLYDAPAGMADWSNELNVFPN
                     GTRRSKPMFRTTSQARILESARWWLSGFFSNIAANSSSDDYDLVIIPEGDGYNNTLSGS
                     CPNGDTSEGDDSAEQFLKIYTPPIITRFSQYLPSTLNLTYLDILSMQNLCAYETAVLGT
                     SSFCALFTPSEWESYAYILDLQFYGDYGFGSPSGRAQGIGYVLELASRLQGKVIEKQVA
                     NVNITYDSNPSTFPLHQPLYLDMSHDDVIVSVLAALGVEYFNIGKDGMKGNISANEVPL
                     NRTFRLNRIAPFGARFVTEIWRCDSSSAADIEVDAGGEVVYENPTVSEGVGKEYVRWVL
                     NEMPVPVDGVSGCESDGGNGFCSLEGFLGGVKEMQELAGFEEACIEGAGSGGGQVGDGR
                     P"
     mRNA            complement(join(7313..7575,7641..8677,8728..8821,
                     8890..8933,8980..9298))
                     /locus_tag="M747DRAFT_295448"
                     /product="DnaJ domain protein"
     gene            complement(7313..9298)
                     /locus_tag="M747DRAFT_295448"
     CDS             complement(join(7432..7575,7641..8677,8728..8821,
                     8890..8933,8980..9085))
                     /codon_start=1
                     /db_xref="InterPro:IPR001623"
                     /db_xref="InterPro:IPR018253"
                     /db_xref="InterPro:IPR026894"
                     /db_xref="InterPro:IPR036869"
                     /db_xref="PFAM:PF00226"
                     /db_xref="PFAM:PF14308"
                     /locus_tag="M747DRAFT_295448"
                     /note="EggNog:ENOG41"
                     /product="DnaJ domain protein"
                     /protein_id="ncbi_M747DRAFT_295448-T1"
                     /transl_table=1
                     /translation="MVADTSYYDALGVPPTATELEIKKAYRKLAIIHHPDKNPGDETAH
                     ARFQEIGEAYQVLSDEELRKRYDKFGKEDAVPGGGFEDPSEFFGMIFGGNAFVDLIGEI
                     SLMKDLTTTMDITMQQMEEEELAASAEEKLNIHDETQAHAAEGTTEGAAQATPAESTTA
                     ASEKPAAAASPSSGTSTPRRYMGQQAIMDKSEEEARMEAAGLSQEEKELRKKEKKKGGL
                     SREQQERLAAYELERKKAREERVNTLATKLVDKISVWTETDKSPDMTRAFEEKIRLEVE
                     NLKMESFGLEILHAIGATYVQKATSFLKSQKFLGISGFFSRLKDKGTLAKETWTTISTA
                     IDAQMTMEEMAKLEERGGEDWTDEKKAEYEKKVTGKILAAAWRGSKFEIQSVLRDVCDQ
                     VLGDKRIKLDKRVERAHALVIAGNIYSKAERDPDEEGDFMAFEQLMAESMTKKGKEDKK
                     KKKKHEHHHEEPTATA"
     CDS             join(<10001..10068,10156..11215,11268..11450,11499..11606)
                     /codon_start=1
                     /db_xref="InterPro:IPR002060"
                     /db_xref="InterPro:IPR006449"
                     /db_xref="InterPro:IPR008949"
                     /db_xref="InterPro:IPR019845"
                     /db_xref="InterPro:IPR033904"
                     /db_xref="PFAM:PF00494"
                     /gene="ERG6_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="M747DRAFT_370089"
                     /note="BUSCO:EOG09262HA6; GO_component: GO:0016021 -
                     integral component of membrane [Evidence IEA]; GO_function:
                     GO:0016740 - transferase activity [Evidence IEA];
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]; GO_function: GO:0051996 - squalene synthase
                     activity [Evidence IEA]; GO_function: GO:0004310 -
                     farnesyl-diphosphate farnesyltransferase activity [Evidence
                     IEA]; GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]; GO_process: GO:0009058 - biosynthetic
                     process [Evidence IEA]; GO_process: GO:0006696 - ergosterol
                     biosynthetic process [Evidence IEA]"
                     /product="Delta(24)-sterol C-methyltransferase"
                     /protein_id="ncbi_M747DRAFT_370089-T1"
                     /sec_met_domain="phytoene_synt (E-value: 9.6e-10, bitscore:
                     32.1, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MGLASNAIYYTFHPSELRSILQWKIWHSPVHERNEKNETETEKAC
                     FKFLDLTSRSFSAVIKELHPELLMPVCVFYLTLRGLDTIEDDTSIPLETKEPLLRGFKD
                     FLEQDGWTFNGNRPEEKDRELLVQFHNVITEFKKMKPAYQAIIKDITDKMGNGMADYCR
                     KAAFDDASVITVEEYDLYCYYVAGLVGEGLTRLFVEAEFGNPALLERARLHKSMGLFLQ
                     KTNIIRDIREDDDDGRRFWPKEIWSKHVKQFDDLFKPEHREAALNCSSEMVLNALEHVE
                     DCLFYLAGLREQSVFNFCAIPQSMAIATLELCFRNPAIFERNIKITKGEACQLMFESTQ
                     NLRILCAAFRKYARKIHKKNTPKDPNFLKVSLVCGRIEKWIETIFPSQNAEAAKRRVTG
                     ELTEQEKKQAEEHAETRKDMYFMMGLMVVIVFITSVVMIFTAWLLGARFDLAWQELRSG
                     NFRPPREIRQKQEL"
     mRNA            join(<10001..10068,10156..11215,11268..11450,11499..11954)
                     /gene="ERG6_2"
                     /locus_tag="M747DRAFT_370089"
                     /product="Delta(24)-sterol C-methyltransferase"
     gene            <10001..11954
                     /gene="ERG6_2"
                     /locus_tag="M747DRAFT_370089"
     mRNA            complement(join(12014..12312,12390..12497,12569..13758))
                     /gene="GPI14"
                     /locus_tag="M747DRAFT_295450"
                     /product="GPI mannosyltransferase 1"
     gene            complement(12014..13758)
                     /gene="GPI14"
                     /locus_tag="M747DRAFT_295450"
     CDS             complement(join(12169..12312,12390..12497,12569..13561))
                     /codon_start=1
                     /db_xref="InterPro:IPR007704"
                     /db_xref="PFAM:PF05007"
                     /db_xref="PFAM:PF06728"
                     /db_xref="PFAM:PF09594"
                     /gene="GPI14"
                     /locus_tag="M747DRAFT_295450"
                     /note="CAZy:GT50; BUSCO:EOG09261XAF; GO_component:
                     GO:0016021 - integral component of membrane [Evidence IEA];
                     GO_function: GO:0016758 - transferase activity,
                     transferring hexosyl groups [Evidence IEA]; GO_process:
                     GO:0006506 - GPI anchor biosynthetic process [Evidence
                     IEA]"
                     /product="GPI mannosyltransferase 1"
                     /protein_id="ncbi_M747DRAFT_295450-T1"
                     /transl_table=1
                     /translation="MASFFQTPSLVYTSAIALRAILLIYGAWQDANSAVKYTDIDYLVF
                     TDAARYVSHGASPYERDTYRYTPLLAWLLLPTSWSGPSFLFSFGKALFALSDVLAGWLI
                     ARSLVSAYGMDAPRALKYASFWLLNPMVANISTRGSSEGLLGVLVIALLWAVLRRRVVL
                     AGVLLGLSVHFKIYPFIYGVSILWWLDRERDGSSSSTSKNNAGDASIITKMINFITPSR
                     IILTLSSLITFSLLNLLMYHLYDTPFLQHTFLHHLTRIDHRHNFSPYSTLLYLSAAGEV
                     QGNFESLAFIPQLLLSVVVIPLVLAKKSLPGAMLAQTFAFVTFNKVCTSQYFLWYLIFL
                     PFYLPRSSMLKAPRFGGAVAAAWVVGQALWLQQGYNLEFLGLSSFVPGLFLASLGFFAV
                     NVWILGIIVGDVGAC"
     mRNA            complement(join(<14299..15297,15345..16455,16532..>16755))
                     /locus_tag="M747DRAFT_314829"
                     /product="C6 transcription factor"
     gene            complement(<14299..>16755)
                     /locus_tag="M747DRAFT_314829"
     CDS             complement(join(<14299..15297,15345..16455,16532..>16755))
                     /codon_start=1
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR007219"
                     /db_xref="InterPro:IPR036864"
                     /db_xref="PFAM:PF00172"
                     /db_xref="PFAM:PF04082"
                     /locus_tag="M747DRAFT_314829"
                     /note="EggNog:ENOG41; GO_component: GO:0005634 - nucleus
                     [Evidence IEA]; GO_function: GO:0008270 - zinc ion binding
                     [Evidence IEA]; GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_function: GO:0000981 - DNA-binding
                     transcription factor activity, RNA polymerase II-specific
                     [Evidence IEA]; GO_process: GO:0006351 - transcription,
                     DNA-templated [Evidence IEA]; GO_process: GO:0006355 -
                     regulation of transcription, DNA-templated [Evidence IEA]"
                     /product="C6 transcription factor"
                     /protein_id="ncbi_M747DRAFT_314829-T1"
                     /transl_table=1
                     /translation="MFHTFEGFENPTLPAAVRGRNQRQQSVGRRVTTLRACTSCRHRKI
                     KCDGEKPCEACRWYKKADLCQYSDPRPSRRHVEKLSTTLDEFRGVLDKLFPGIPAETLV
                     NLPRDKLLELTGKGPSQMQTQAPHPASPATSASVEAHASPASSEDGNLESLQTIPDHTT
                     DDRELKGSELTSTVSDDVNALSLSAKQPSSYLGVSSIHAVLKVIVWLEPSSLSHLSRAP
                     ATGVRRESVMDIASPEAQAWQVFGSQPHHGTSTHSPLQVPETQLLDAYFTYFQPFVPML
                     DEQYFRQTYLSARRKDKQWLALLNIVFALGSIAATPADDMSHQAYYMRSMSHLNLESLG
                     SPHVETIQALGLMGGYYLHYSSQPNLAYSMMGAALRMAAALGLHKEVSDGQYGNGRNRL
                     SSVDHKRRVWWSLFCLDTWGGMTLGRPSMGRLGPAITVKLPHYRETGNVLDLLPLLENV
                     RFCKIATQIQEVLAVAPLTKPHEMAHLDSQLLEWYDNLPYILKDHEPCSESIAITRTVM
                     KWRYYNQRMLLYRPTLLSYAMRRVPYIVLRSEERTAIERCREIAEATIQDVAAKAQFHQ
                     MSGWNAVWLIFQAAMVPLLGLFLNDGTVDDPRATAEACQAQVETTMLVLERLEPWSPAA
                     KSTLEAVSRIFEAGKRGPSVIGEAHSINSGSCVTSTEETLGAVPGVSPMQVDFGRAIPH
                     DSGFVDPFEPQFINDSAGQYLWDFLSWSDSNLLQGLADIDNVNNGPLFPQEERNAKYGS
                     SDTAFFGGQLGDSTFFINSGPSFY"
     mRNA            complement(join(18372..19184,19260..19404))
                     /locus_tag="M747DRAFT_295452"
                     /product="hypothetical protein"
     gene            complement(18372..19404)
                     /locus_tag="M747DRAFT_295452"
     CDS             complement(18761..19108)
                     /codon_start=1
                     /locus_tag="M747DRAFT_295452"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_295452-T1"
                     /transl_table=1
                     /translation="MARLALRTLFWESSSGGSPPLSPTIVPDSSQDLQIKRSPVTNFPV
                     STSPFFVGLVATTKTVRAPSFLSDPVKRQGRREVPSFGPLPLAYPSSLGITTPHYSSSC
                     KTPGASRLPES"
ORIGIN
        1 gtggtcgata gccgaggagc ttgagaaaga tctggcgcga actgagttca aggggcggac
       61 actggttctc aaagtaaagc tcgctacatt tgaggtgttg tcacgacaat gccagcctcc
      121 acgggcggtc tcgactgcca aagatctgta tgcgttctca cttccgatgc tggagaagct
      181 tgaaaaggaa atgcctgatc tgaaaatgcg cctgcttggt ctccggtgca ccaaccttgt
      241 gagcacaaag aaagttggga tcgagctctt cggcttcact tcgcggccga agcctgcttc
      301 agacatgtcg accgatcctc cggttgagca ggagatcgag acagaggagg cctttgagaa
      361 agcggcacgg gaggaactac aagaggagct cgatgatttg gagaagctga gccaggaggt
      421 atccgaggcc gcagaattga agcaggatgg gaaaggagta gatgcatcgc agcctgtata
      481 ttgggattgc ccgatttgtt ctcgacctca ggtggcggaa gatcgtgcat tcaatgacca
      541 tgtggactac tgcctatcac gacagacgat caaggaggct gtccaaggtg cctcgagtga
      601 tgttccgcct gagcctctgg ctgcatcgaa gacacgaaag cgaagagcga cggaatcacc
      661 ggatccgcga caaaaacggt tgttcttttc gtgatgactt ctctatagtc cacactatac
      721 taagtcccgc agagccgggc tcgtcttgca gcccaggtca acttgcagga gtaggaaccg
      781 tcagtctact tcgaatattc tcagagcgat taacggcatg gcagccgctc tgcaactcac
      841 atcccgcact cgatgccggc cacggtggca ttgcgtctga caccgacatg acagacgctc
      901 ccagtctttc gggaaagaag tgatcaatca gatctacatg atctggtcac gagaaacaac
      961 catccattcc caacggtcaa tacctacccg ttttcgcgac ctccttcata aggagcttct
     1021 cggttataaa attcattatg tgcagcttgt ttataatgtt ggaattcacg agagctttac
     1081 catcgcaggc ttgtatatag gagagaacga tagaacctta tcatcactgc tatctactaa
     1141 ttgacagatc aaccatcggg tacctggcgt tgatgaagaa atatatcatt gccaataata
     1201 tcgctgtaag gcagtattgc atgcatgaag gggttgttgt ttatgctgca tcgattaatt
     1261 gttggctggc acccagccag acggttctat taataggtta attaagggtt agttaagtac
     1321 tgacggatgt atctacatta aacgaggacc catccacgac actccttgac gattctatac
     1381 ttagctactc aacaaataat actacgaaag ggatcataca ttggaaagca caacctcgca
     1441 tctagtattc accaagtatc tttcgtcaaa ctcaaaccac caagcaacag cactcccgat
     1501 agaaatacca tcacccccga taaacttcac cacatatcac aaacccgcat tgacaaccag
     1561 gaatgtggat ctagccccct ccctctcctc ttattcaaga tcaacgtggc agacggcccc
     1621 ttgcatcccc gaatagttgt ttgtcacaca tcacgtggtc aacagcagct ccccatggag
     1681 acgaatgttt tgatcgacga gatctgaacc gataaggctt gcagggaatg aatcaatcaa
     1741 atcacatctg tcatgtggga aagggcagat gatcagaaag atatactccg gttccgtgga
     1801 ttacaatagt gtagggtcgt gtagtgtagg gggaaaaggg aagcgatggg gtgatcggcg
     1861 tggtggttgt ccggttactc ctccggaggg agccgcagct ccgacttcac ccatggtcgg
     1921 ggggatgcat cagcccatgt gaaggggact gcaatgcgca agggtgggtg caattgtagt
     1981 tactcttact actatttttg aagatatgaa tggtttcaag tgttgataat tagaagatga
     2041 aagtgagaac gtgtatagac cgaggatagg aaatagttat tgggatagaa acccatcaag
     2101 ggatcaagtg agttgcggtg aaaggggcca ctggagacta gccggattag gcggggggat
     2161 gttttgcacc caaacattaa ttatccttct ttcttctcag gtgttgttga caacaaattc
     2221 aacgcaccgc atcgtcatcc cacccggttt tcttctcgcc tcattttttc cctcccttcc
     2281 agcctcggcc gtttcctctc ctcatctgga cggtcaagaa cccgctgtcg actggctggt
     2341 gccatcatca tgcttgcaga ttctcgagca ctgtcgcaat gccatgagcc gctctccttt
     2401 ccgcccctcg actcccgcaa ctatgaacgc cgccgataaa caaaacaatg gccatctcgc
     2461 caaaccactc acccccgccc tcagcgccgc ctttcatcgc tcccagaaat cccctctgac
     2521 tcctcgactc gctactcccg ggggttatcg aactcccaag cgactggccg cctccgaaca
     2581 tccctcgtcc gccccctcca agcgggatcc cgagccatca tcatcatccc tgctcagtgc
     2641 caacgttacc cctcgatccg gctcccgcaa cagcagacgc gatggtgctg tttcctcccc
     2701 caacaacaac aacaccccga ccaacgggca acagtcgccc caggtgacct ggacacaacc
     2761 gcatgtgggc cagctgtcaa atacggggcg actccggacg gagcggagtc ccgttcgggg
     2821 ggcaatgctg gaaccatcgc ggacaacccg ggccaggacc gtgacgatgg agtccaacca
     2881 tctttcccgg cctaattctg cgtcggataa ttcagccggg gcccccatgt tttttcacgc
     2941 ctccgatgca cgatcgacca tttccgagca ggagccccgc ccgaagctgc agacaaaaac
     3001 gtccggtacc acttttatct acgcaaacgg ggcgcaagag aggcagtccc cggtaagtga
     3061 ggtggggggt acgtataaac gccggtcgat tggcttgacg cgatcggtgg tgtccgcgaa
     3121 accgtctgcc tcgccacggc tgcgaccagc ccgggtggac tcgaatccgc ggctgtctga
     3181 tgggccgtct gtagtcgggt cgcaggatga ctcgtttgaa gcagggtcac aggctcatag
     3241 tccacccatg agcagcgtat cagcgcgacc gattccagcc gtgcgacacg ttaaatcgtc
     3301 gagtctcgac tctggccaca gtggactctc gcctcctcag aaggaaggtc tgcggccaag
     3361 tccgctgatc atatcgccat cagaaccaaa gatcgatgct agcacgattg catccgaacc
     3421 gctgccaggt ctccggccgc gagtgttcag caatgggtcc atcgcttcag tggatacgca
     3481 taactcgggg atgcagagcc cgtccaagtc agaaagcgga caggctaacg gcgcccttaa
     3541 tgcgcgtacg gagcggaaga tcatggatct tgaaatcagc aactcatcgc ttctcgccat
     3601 caaccgcacg ctagaacggg agatgcggaa gcagaacgcc gagctgcgga gataccgacg
     3661 cctcagtcgc tcagggcgtc tatccatggc gacgtccagc cggtccgtgt ccggcgctct
     3721 ctcgattcct ccggaagttg aggaagcaag cgagcactca tcggtgcggt cgccagaaga
     3781 actttccgac tttagcgacg aagactcctt ggaagacggg gtgctgagcc cggactcgca
     3841 ggcagatcag gactcccagc atcgtgcgcg ggatgagaaa cggttcctca tcgacctggc
     3901 gaagcatcag gagcttcttg ccgacagcca gcggctgaac cagagcctca agcggtgtct
     3961 aggatggact gaggaattga ttagggaggg acagcgcgca ctcgaataca atgtccatgt
     4021 aaacgacgtg caactgggtg gacgcgtgct caccccggag gagctgaatg agctgaacga
     4081 gctcaacgag ctgcacgagc agcaagaact cgaggatatt tctcgtccat caagtcggag
     4141 cgactccgaa ccgccttccg aggacggcag ctagctgcat tgcatactac tatctcatct
     4201 agactaatac ggcgtcgctg gtgtactgtg ctatttgttc tgaccgacta aagctggcat
     4261 ttagtcttag cttttcctta tgcgttttga attgtttgat tgtttgatcg tgttgatggc
     4321 gatagatggc cggccggcag ctgttctgag ctagataccc atacgcgtga attttttcta
     4381 gcatatacca tactatatac catataccac ttttgcatgc atccacaccc tcacttctct
     4441 ccagacaaca taaaaaccac gaaagtagta atcctaaggc cttccatccc caacctggcc
     4501 cccaccactg cccgccccct caatacacgc ctcctcgaat cccgccaact cctgcatctc
     4561 cttcacaccc cccaggaacc cctccaaaga gcaaaaccca ttccctccat ccgactcaca
     4621 cccagacacc ccatccaccg gcacgggcat ctcattcaac acccaccgca catactcctt
     4681 cccgaccccc tcactaaccg tcggattctc ataaaccacc tccccacccg catccacctc
     4741 aatatccgca gcagaggaag aatcacacct ccaaatctcc gtcacaaacc gcgccccgaa
     4801 cggcgcaatc ctattcaacc ggaacgtgcg attcagaggg acctcgttcg cactgatatt
     4861 ccctttcatt ccatccttcc cgatattgaa gtactccaca cccagcgcag ccaacacaga
     4921 cacgatcacg tcgtcgtgag acatatccag gtagagtggt tgatgcagcg ggaatgtgct
     4981 cgggttcgag tcgtacgtaa tgttgacgtt cgcaacctgc ttctcgatca ccttgccctg
     5041 aagacgagat gctagttcga ggacgtagcc gatcccctgg gcccttccgg agggagagcc
     5101 gaagccgtag tccccgtaga actgcagatc gaggatataa gcgtaggatt cccattcgga
     5161 gggggtgaag agcgcgcaga aggaggaggt gccgagcacg gcggtctcgt atgcgcagag
     5221 gttttgcatg gagaggatgt ccagataggt taggtttagg gttgagggga ggtactggga
     5281 gaagcgggtg atgatggggg gtgtgtagat cttgaggaat tgctcggcgg agtcgtctct
     5341 atttttatca ttagtaggtg ggcaatttgg gtataagagg gatgggggat atgcgttacc
     5401 cctctgaagt atccccgtta ggacagcttc ctgacaaggt attgttgtag ccgtcgccct
     5461 ctggaatgat caccaggtcg tagtcatcgg aggagctgtt ggctgcgatg ttgctgaaga
     5521 agccgcctat acgtcttatt agcattcttc tttcatctac taggggaatt gaattgaatt
     5581 gaaagaatta gagaaagagc cgggggggag acatactcaa ccaccacctc gcactctcca
     5641 agatcctcgc ctgcgatgtc gtcctaaaca tgggcttgct cctcctcgtt ccattcggaa
     5701 acacattcaa ctcgttactc cagtcggcca tgcccgccgg ggcatcatac aatacacgtc
     5761 cgtaccggga ccagtggaat gcacccgagg tagcttccgt cgctgcgccg gtggggagaa
     5821 gggcctctgt gcccatgagg tatctccagt tattgaggaa agaaagaggg ccagtggcga
     5881 gggtgctgtt tgggtgtgct tgagtgtagt tctttagctt ctgggcgaag gattccatgc
     5941 tgtcggcgtc gaggaggtag gaggtgggat agcgttgcgc gtgccggtgg aggatgtgcg
     6001 cttgggttag ttggcaggtc ttgggcgtgc ccggggggat gccgaagcct gggctcgagg
     6061 tgtaggggga taggttgccc catgttgagt ggaggttgaa gggggtggtg gtggtgtttg
     6121 ttgcggtggt gagggttagg aggcacagga gtgccgttgt gaggggggag aggaggatca
     6181 tgatggttac ggtgtggggg gtggctacat ggggagaggg atggtagaag ggggggggaa
     6241 gaggtgaggt ggttatatat gggagagttc agtgcggaat aattatttgg attgtatcta
     6301 tgctagaact gagtgggaat tgagcggagt ccgtcgtatc aatgctggcc agcctgctat
     6361 gtgtggtgcg ggggggctgg tttgctaaat tgttaggttg gtaggaaaga agtagtagat
     6421 aggcaagtat tgcggagtcg aagctttaga ccggctcaag tctaggagaa atctgctaac
     6481 ggatccaggt tacgcagtgg tgctactgac cagatagtga tagtgtggtg gtgaagtcca
     6541 tggagcggga aagccttccg ttgctgattg tggtaattgg tcgcgtgagg ttggagagag
     6601 agacggagag agaccgccaa tcctgccaaa gcggggttgg agagcagcag agagccggta
     6661 agatggaatc cctcctggca gtaggaaagc ttatcagaag gtgagacacg gcgggacggg
     6721 ttcggtagtt tctatctcca gtttttttga gaggggcgcc ggtgaatgtt aggggtagga
     6781 cctgcttccc aggttatata ctgattacta gtacaacaat gtaggtaggc aatcattgtt
     6841 gtgagttgag ataaggaaca gtagagctgc ttatgagtgg cacgtaagat atcccattga
     6901 ctgatgaaat agtactactt ttcttcctgc atgcagtttt ctgtctgtct caccccgcag
     6961 ccactaccgc tacacctgca gggttagttg gcggttgtac cttctatcgt acgacgtcac
     7021 ttactccgca tgtaaccaaa attccttgga agtcggcgat atccggttca gtaacggatc
     7081 atgagttggt attagtcgca gtagtagtta gtggttggtg ctgattaacc ggagcacagg
     7141 agaccgttac ggccgagata tattctgtcg gaaggtgaac ttagtaccac cactaatagt
     7201 agtaatcgtc tcagccctac ggggcaccac cgccagcagc agcagcagta gtgagtggta
     7261 aatgctgcga cagtaatcac tataatgacc taccagtagt aacatgaatc taattgatat
     7321 tcattctgct tacatctatt acgcatctgg cagggtatgc cgggtcgcta ctcaacatat
     7381 atccaatgtc cagtctgaac cacaaaaaca aaaatagact atgcaaggta tctaggcagt
     7441 ggctgtgggc tcttcgtggt ggtgctcgtg cttcttcttc ttcttcttgt cctccttacc
     7501 cttcttcgtc atcgactccg ccatcagctg ctcgaacgcc atgaagtcac cctcctcatc
     7561 aggatcgcgc tcagcctgac acagttagca tacatccaga cccctgtagt gaatcccatt
     7621 gtagtgaacg gtgaacatac cttggagtaa atgttacccg caatcaccag agcatgagca
     7681 cgctcaacgc gcttgtccag cttgatgcgc ttgtctccga gcacctggtc gcacacatca
     7741 cgcagcacgc tctggatctc aaacttgctg ccccgccatg ctgccgccaa gatcttgccc
     7801 gtcaccttct tctcgtactc ggccttcttc tcatccgtcc agtcctcgcc accgcgctcc
     7861 tccagcttag ccatctcctc catggtcatc tgcgcatcaa tggcagtgga aatggtggtc
     7921 caggtctcct tggccagcgt gcccttgtcc ttcagccgcg agaagaatcc ggaaataccc
     7981 aggaacttct gcgacttcag gaaagaggtg gccttctgca cataggtggc gccgatggcg
     8041 tgcaagatct ccaaaccgaa cgactccatc ttcaggttct ccacctccag ccggatcttc
     8101 tcctcgaacg cgcgggtcat atcagggctc ttgtcggttt ccgtccacac gctgatcttg
     8161 tccaccaact tcgtggccag agtgttgacc cgctcctcgc gcgccttctt gcgctccaac
     8221 tcgtacgccg ccagacgctc ctgttgctct cgggacaaac cacccttctt cttctccttc
     8281 ttgcgcagct ccttctcctc ctgggacaga ccagctgcct ccatgcgcgc ctcttcctcc
     8341 gacttgtcca tgatggcctg ttggcccatg tagcggcggg gggtgctcgt gccggagctc
     8401 ggggatgcgg cggcagcggg cttctcggaa gcggcggtcg tcgactcggc gggggtagct
     8461 tgggcagcac cttcggtagt gccttcagca gcgtgcgcct gggtctcgtc gtggatgttg
     8521 agcttctcct cagcggatgc ggccagttct tcctcctcca tctgctgcat ggtgatgtcc
     8581 atcgtagtgg tgaggtcctt catgagcgag atttcaccga tgaggtcgac aaaggcgttg
     8641 ccaccgaaga tcatgccaaa gaactccgag gggtcctctg tagggcatta gtatccgact
     8701 gattgcctgc gagatgcaat gtcttaccaa aacctccacc gggaacagca tcctcctttc
     8761 caaacttatc gtagcgcttg cgaagttctt catcgctcag aacctgatag gcttcaccga
     8821 tctgtcatag tagagagtgt gtgtgagcgc atgattttga gagcagacaa acaaacagta
     8881 tctacccacc tcctggaatc gcgcatgcgc agtctcatca ccggggttct tatctacgac
     8941 gatcagtagt ggtcaaccag aggacagcgt gccacgcacc cggatggtgg ataatggcca
     9001 gtttgcggta agccttcttg atctcgagtt cggtcgcggt gggcggcacc ccgagggcgt
     9061 cgtagtagga agtgtcggca accatggcgg gcgatgtgag caggacccaa ccacgcaatc
     9121 aatctagcgg tcaccgatgc agaaaaatca aggccagccg gcaggcgtgt gacagaaata
     9181 gaaggtgatc gggaatagga tgtgctggta gcgacaacag gatcagatgt gtctcctgtg
     9241 attttttctg cctaaacgat gttattttgg cttttagttt tccgctggat ttcttccgtc
     9301 atggcgggga gagagacaga cagtcacttg caatggggga atggcctgag gcgggcaggc
     9361 agccagtgcg gttgtcacgt atggttagca agtggtcaca ttccacacag atagcacgga
     9421 atacatgcat cgatccatgt aatctgccgt aataccgagt tatgcgcccg cacgcgctca
     9481 gccgccagcc cagagccgct agccgcgccg ccttccaagc gggcctttaa aattttcctt
     9541 ctttcgcttt cttttcttct ttttcttcct tttcctcttc gtcttctgtt tattcctctt
     9601 ctccctcctc ttctcctctc tccccccctg attttccctc tcctcccaat tgtttactta
     9661 tttcctcttc ctctacatct ctctctaacc ccctctccct cctctacctc ctcctccgcc
     9721 tccctcctac tcctacattc ctctgtctgc ttgactggat tccccgtctc ctccccgctc
     9781 atcctcccca gccagtgagg cattcgctcg ctgtgcttgt acattattgt accatcccat
     9841 ccctttcttt tcctctcgaa ttccgttgat tcggtcattc tcccgcattg cttccctctg
     9901 ctttccattc cctttcttat tacgtgtaat aattccccat tttaccctaa ttcttctatt
     9961 tcgtcatttt tgaccgttcg atcgtaatct accctccacc atgggtctcg catcgaatgc
    10021 catctactac acctttcatc cctcggaact gaggtcgatt ttgcaatggt tggttccggc
    10081 ccttgtcctc gaccggctat gatgggcttt agtgtgttgt gccaacgctt acgaaggctt
    10141 tgcccgtggt cataggaaga tctggcactc cccggttcat gagcgcaatg agaagaacga
    10201 aaccgagact gagaaggcct gcttcaaatt cctcgacctg accagtcgga gcttcagcgc
    10261 cgtcatcaag gagctccacc cggagctgtt gatgcccgtc tgcgtcttct acctcacact
    10321 tcgcgggctg gacaccatcg aagatgacac gtcgattcct ttggaaacaa aggaacccct
    10381 gctgcgtggc ttcaaggact tcctggaaca ggatggctgg acgtttaatg gcaaccgccc
    10441 cgaagagaag gaccgtgagc tgctggttca gtttcacaat gtcatcaccg agttcaagaa
    10501 gatgaagccc gcctaccagg ccatcatcaa ggacatcact gacaagatgg gcaacggtat
    10561 ggccgattac tgtcgcaagg cggccttcga tgacgccagc gtgatcaccg tcgaggaata
    10621 cgacctgtac tgctactacg tcgccggctt ggttggtgaa ggactgacgc gcctcttcgt
    10681 cgaggccgag tttggtaacc ctgccctgct ggaacgcgcg cgtctgcaca agtccatggg
    10741 actcttcctc caaaagacaa acatcatccg agacatccga gaggacgacg atgatggacg
    10801 tcgcttctgg cccaaagaga tttggtccaa gcacgtcaag cagttcgatg atctgttcaa
    10861 gcccgagcac cgcgaagctg cactgaactg cagctccgag atggtgttga acgctttgga
    10921 acatgttgaa gactgcctgt tttacctggc tggcctgcgt gagcagagtg tgtttaactt
    10981 ctgcgcgatc ccgcaatcga tggccattgc cacgctggag ctctgcttcc gcaaccccgc
    11041 gatcttcgag cgtaacatca agatcaccaa gggtgaggcg tgccagctga tgttcgagtc
    11101 gacgcagaac ctgcgtatcc tctgtgctgc cttccgcaag tacgcgcgca agattcacaa
    11161 gaagaacaca cccaaggacc ctaacttcct caaggtcagc cttgtttgtg gacgggtatg
    11221 tttttttatt cccctctgct ctggttgggc tgcgctaatg attatagatt gaaaaatgga
    11281 tcgagaccat cttcccatct cagaatgccg aggccgccaa gcgtcgtgtc actggcgagc
    11341 tgacggaaca ggagaagaag caggccgagg agcacgccga gactcggaag gacatgtact
    11401 ttatgatggg tctcatggtg gtgattgtgt tcatcacctc ggtcgttatg gtatgtgcct
    11461 tcacctgaca tctaattgaa tttggctaac ccgaatagat cttcactgcc tggctactgg
    11521 gtgcgcgatt cgacttggcg tggcaggagc tgcggtccgg taacttccgg ccaccaagag
    11581 aaatccgcca aaagcaagag ctgtaatgca ttctacggag ttatgactga ttgatctact
    11641 agctgcggag gcttatgtct tatacctttc tgcccaccgc ttatctacta atacattacc
    11701 cttctttctt cttcctttct taggtctata tttctggacg atgaactagc acggatgtca
    11761 aattgcgatc cagtctttcc atgactgtgg ttgtgccgaa gaagtgctga tattgagctg
    11821 aatattctga ccagcgacgt actagatgtg tgtcttacaa cttaagtgtt gaggtggcaa
    11881 acatccattg aggacctgga acaaatgtag tcatgtaaac acgaatttat atattaccac
    11941 ttgaacaata tgacttctgc ttgataaaca tatttttctc taaaacccat cttgtaacct
    12001 tgacatagtc ttaaggagta ttccactgta ctcaacccca atcccatact tgaacatatc
    12061 tacctattac cgcacacaat aatccctaaa taattacacc atatctcccc tccaacacaa
    12121 cacaaccctc aatacttaat acagaacata aagaaaaaaa aatctcaact aacaagcccc
    12181 aacatctccc acaataatcc ccaaaatcca aacattcacc gcaaagaacc ccagcgaagc
    12241 caaaaacaac ccaggcacaa agctactcag ccccaaaaac tcaagattat acccttgttg
    12301 caaccacagc gcctgccacc aaccaatcag tacacaacct acatggaaca tacaaaagtt
    12361 aagccaaaag gagagagaga aacacatacc tgcccaacaa cccacgccgc cgcaactgct
    12421 cccccaaacc gcggagcttt tagcatcgaa gaacggggta gatagaatgg taggaagata
    12481 aggtaccaca gaaaatacta ccatccctat cagcccatcc cattccaaat agcttatggg
    12541 caaggggata aagatagggg taactaacct gactcgtaca aaccttatta aacgtcacaa
    12601 acgcaaacgt ctgcgcaagc atcgccccgg gcaaactctt cttcgccagc acaagcggaa
    12661 tgaccacaac agagaggagt aactgcggga tgaacgccaa cgactcaaaa ttcccttgca
    12721 cctcgcccgc agcagagaga tagaggaggg tactgtaagg cgagaagtta tggcggtggt
    12781 cgatgcgagt aagatgatgg aggaaggtgt gttgcaggaa gggggtatcg tagaggtgat
    12841 acatgaggag gttcaggagg gagaaggtaa tgagggagga gagggtgagg atgatgcggg
    12901 agggagtgat gaagttgatc atcttggtga tgatactggc atcgccagca ttgttcttag
    12961 atgtgctgct gctgctgcca tcacgttccc gatccagcca ccaaagaatc gacaccccgt
    13021 agataaacgg ataaatcttg aaatgcacac tcaaacccag cagcacacct gcaagaacga
    13081 ccctcctgcg gagaacagcc cacagcaggg cgatcaccag cacgccgagc agtccttccg
    13141 aggaccctcg agtgctaatg ttcgcgacca tggggttgag tagccagaag ctagcgtact
    13201 tcagggcgcg gggggcatcc attccgtacg cggaaacgag ggatctggcg atgagccatc
    13261 cggcgaggac gtcggagagg gcgaagaggg cttttccaaa ggagaagagg aaagatgggc
    13321 ccgaccagga ggtcgggagg agcagccatg ctaggagagg cgtgtagcgg taagtgtctc
    13381 gttcgtaggg cgaggcgccg tgcgagacgt agcgggctgc gtcggtgaag acgaggtagt
    13441 cgatgtcggt gtacttgacg gcggagttgg cgtcttgcca ggcgccgtag atgaggagga
    13501 tggcgcggag agctatggcg gacgtgtaga ctagggaggg ggtttggaag aaggacgcca
    13561 ttttggatgg cattttgatg tagagagagg tcgtgttgtg gttacttcat cggtgatagc
    13621 ttactcctga tagtagatcc acaatgaagc cttcgacgac cggatggatc gtcttaggat
    13681 gccagggcaa tttagtagtg gctagtatgt acagatccgg ctgatctcac catcctatgt
    13741 ctatttggtg ggcatcgtgg gttctggttg gttagatgaa gctatcccgg ccgcgaggaa
    13801 acgtgaccgg atcgatggct gagtcagcag cgagatgatc ttgcccgatt aggatgaaac
    13861 tgtgtactcg aagatgagag aagaaattcg gaatattttc tttctttctg ttatgcctta
    13921 gctttcttgt ctaagatatt gaactaggtg gttttatcgg agacgtaagt atcttttata
    13981 ttctcaatcc atagtgagga ggcgcccacc catatcataa cctactatgt aaccatagct
    14041 agtttgaata cactttgtag atcaaaaata tattgctgaa gcagttcttt ttgctatcgt
    14101 gataccgtgt tctcgacata aatcctccga atcctccgaa tcgcccgtaa atgcatcaat
    14161 cataaataat tctgtaatgt ggagatcgct aacatatggc ggggaacaac aaaacaaaca
    14221 tagagcgagt gaataataga acaccatgtg acaaaagtga acaccggcag cgataaggct
    14281 gcaccctgta agtacagcct agtagaagga cggccctgaa ttgataaaaa atgttgaatc
    14341 tcccaattgg cctccaaaaa acgcagtgtc gctggatcca tactttgcat ttctctcctc
    14401 ctggggaaac agtggtccat tgttgacatt gtcaatatca gccaaaccct gcaacaagtt
    14461 gctatcgctc caactaagaa agtcccatag atactgtcca gcagaatcat tgataaactg
    14521 gggttcaaat gggtcgacaa atccactgtc gtgtggaata gcgcgaccaa agtcgacttg
    14581 catcggagat accccaggaa ctgcgccaag agtctcttca gtagacgtta cacagctacc
    14641 gctgttaatg ctgtgggctt ccccgatgac gctggggcca cgtttaccag cctcaaatat
    14701 tcgggaaaca gcctcgagcg ttgatttggc ggctggactc caaggttcca agcgctccag
    14761 gacaagcatt gttgtttcca cttgagcctg gcacgcttca gctgtcgctc ttggatcatc
    14821 aaccgtacca tcattgagaa acaagcctag aagagggacc atagcagcct ggaagataag
    14881 ccatactgcg ttccagcctg acatctgatg gaattgtgcc ttggcggcta catcttgtat
    14941 ggtagcctcg gcaatctccc tacatctttc aattgccgtc ctttcttcag acctgagcac
    15001 aatgtatggt acgcggcgca tggcatagct gagcagggtg gggcgataca agagcatgcg
    15061 ttggttgtaa tagcgccact tcatgacggt tctcgtgatc gcaatcgact cagagcatgg
    15121 ctcatggtct ttaagaatat aaggaaggtt atcataccat tccaaaagct ggctatcaag
    15181 atgtgccatt tcgtgaggtt ttgtcagcgg tgccacggcc aggacctcct gtatctgtgt
    15241 cgcgatcttg caaaagcgaa cattttccaa aagtggtaga aggtcgagca cattgcccta
    15301 agtatgtcag ttagacccat tacaacacac aacgtatcac atactgtttc tctgtaatgt
    15361 ggtagcttaa cggtgattgc tggacccagc cgacccatgc ttggccgtcc caaggtcatg
    15421 ccaccccacg tgtccagaca gaaaagagac caccataccc gacgtttatg gtcaactgaa
    15481 gatagcctat tcctgccatt gccatactgg ccatctgaca cttccttatg tagccccaga
    15541 gcagccgcca tgcgcaacgc ggctcccatc atggagtacg cgaggttggg ttggctgcta
    15601 tagtgaaggt aatagccacc catgaggccc agagcttgga tagtctccac gtgtggtgat
    15661 ccaaggcttt ccaaattcaa atggctcata gaccgcatat aatatgcttg atgggacatg
    15721 tcgtcggccg gggtggctgc tatgctgccc aaagcaaaga caatgttaag taacgcgagc
    15781 cattgcttgt ctttcctgcg cgcagaaaga tacgtttggc gaaaatattg ttcgtccagc
    15841 attggaacaa aaggttggaa gtaggtgaag taagcatcga gcagttgagt ctcgggaacc
    15901 tggagtgggc tatgggtgga cgtgccatga tggggctgtg acccaaaaac ctgccaggcc
    15961 tgggcctctg gagatgcaat gtccatgaca gattctcgac ggactcctgt ggcgggtgcg
    16021 cgagacaaat gagagagaga gctcggctcc agccatacta ttacctttag cacagcatgg
    16081 atggaagaga cacccaaata ggaagatggc tgtttggccg agagagataa agcgttaacg
    16141 tcgtcggata cggtactcgt tagctcagaa cctttcaatt cacgatcatc agttgtgtga
    16201 tcaggtattg tctgtagaga ctcgagattg ccgtcttcgc tggatgctgg cgatgcgtga
    16261 gcctctaccg atgccgaggt tgctggggat gccgggtgtg gcgcttgcgt ctgcatctgg
    16321 gaaggcccct tgcctgtcag ctccagaagc ttgtcccgag gcaagttgac cagggtctcc
    16381 gctggaatgc cagggaagag cttgtcaagc actcccctga attcatcgag tgtggtcgac
    16441 agtttctcca catgcctgct tgatcgatac atttgtcagt tttgggtcgt ccctcaatgc
    16501 cggctgctat ggaagaaggg gacagtcaca cctgcgagat ggccgaggat cagagtactg
    16561 acacaagtct gcttttttat accatctgca tgcttcacat ggcttttcac catcacactt
    16621 tatttttcgg tgccgacaag atgtgcaggc gcggagcgtc gtgactcggc gaccgacaga
    16681 ttgttgacgt tgattgcgtc cgcgcacagc agccggaaga gttgggttct cgaacccttc
    16741 aaacgtgtga aacattgcgt tgcgatcggg ggatagtttg ctggagtttt tgtttgacgg
    16801 atagtcggga agtgtacccg ttgagacact ttaggggtgg cgagattaac tcgaaggggc
    16861 cattgacacc gagtcgcagg gaaaccagta ggttagatgc accagagagc agggatcttt
    16921 gtttgtcagg agggggaaaa tagcaagtgg atcgaataga ccgggcaaag tagtccaagt
    16981 cagttagtta tgcaggtaat cagttagtcg ctgcagtggt cattgtccgg ggaaacaatg
    17041 aggtatgaag tagacgaaaa gcaaagaaag gcccatcaaa cgaagattgt aaagaggaag
    17101 aaaaacacaa tatatccacg cgggaactca gctcctgttt tggggaagtg agcaggcaag
    17161 cctcggggtt tgatgatcat cggcagcgtt gacgctggga atatcacggt ttgcaccgag
    17221 agaaagtagg cggtgcccaa cagcggaagt tcctggacga ggaacctcgc aggccaccag
    17281 tggtcagcat ggcctccacc cccgcatttc gtccttttaa tttattttat gcaggttgcg
    17341 accgtttctg tctggtttct gcatgctggc agacgaaccg acctgcagac cctgttggct
    17401 gcctactata ttcaaccctg cgcctaatta tacgcagggt acgagaaggg ttgtgtgatg
    17461 cgctcacaga ctcggcaaac agcacgcggt ggtctgttct cctggcgcct gaattcgtca
    17521 gtccagtaaa cctctccagc atggaattat acacgcttgg gtgtgagggt ggtgcatcct
    17581 tccacctatc actggcactc atcgagcccc gagtctccga gtgctctctc tatttctggt
    17641 aaacgctagg ccttgttccg gcttgagggt attgtccaat atatggccga tgcacataga
    17701 tctgaggcct tggcccacat cagaaacctt tgctcttaca ccccgtaccg tctctataat
    17761 acgaatttac gacaatccac accgagcttt tgagatatgg agcttgggag atggacctgt
    17821 aactcagggg tccagaggaa agagtagtgg agtgggcttc cgctagggcc cggctactcc
    17881 tgagtccaag agctccagat ggtagtgcgg gagattgagt atagcaacgc cggcccacca
    17941 cgctcagaca ttgtggtgcc acctgattgc tttatggcca ggaaaagaag taagaacatc
    18001 cgagtgtctg acaaggttcg ccggatgtaa tcggcgtgct tcatggagaa ctatcctttc
    18061 atccgcgacc tgaaagctta ctgttcctgg gtcgccctac accaagtcgt ccaaaggggg
    18121 gaaaggctat cagggtttat tcattattgt gtcctttcca gggtcttcat ccagttcggt
    18181 tgctgggtag aatttgcctc cgccaattga aagcgcgacc ccgcatgagg tggccaggtt
    18241 ctcatttaca aaattaatta aatcccgtgc aggtgtcaga tgccggagca attttgtcgg
    18301 gggacttgct aggcttactt gtggaaggcc cgctggagtt catggacact tgccattctg
    18361 cgatacaacg agacgtagta gtcttccaga atcgcttggt gtagatcggg ggtgactgac
    18421 agtgcacatc acgtctgtga ggcagtcttg tcgatttttc agcagctggg actcggggtg
    18481 aaccgaaccg tctcagggga caagggatcc ggtgcacgac aatcatttcg acttgtcggg
    18541 aagatgacag ccaatcgccg agatactctc caatagcagt ggcgatgaac aggctaattt
    18601 caccaaaagc caagagtgag acattttatc cttttcacat gcacgccaag cgagcgcggc
    18661 acctgatcgg atggccaggg ccattttacc cagaggtcct gtatcatgga tagcaggcac
    18721 gaaaatgccg agaaaggagg ggtgagtcgg ttactagcgt tcaggattca ggcagtcgac
    18781 tcgctcctgg tgttttgcaa gaggatgagt agtgaggagt cgtaattcca agcgacgagg
    18841 ggtaggctag tggcaaaggg ccaaaggatg gcacctcgcg acggccttgc cgttttacgg
    18901 ggtcgcttag gaacgagggc gcccggaccg tcttggtggt cgcaaccaag ccgacaaaaa
    18961 aaggtgaagt gctcactggg aagttggtga cgggcgatcg ttttatctgg agatcttgag
    19021 agctgtcagg tactatcgtg ggcgataaag gaggactccc accggaggat gattcccaga
    19081 atagcgtgcg gagcgccagc cgtgccataa ccggtatagt cggagaggaa ccgctcaggt
    19141 gtctcacaat agacaccgcg cggtttcgaa tagaaagtga atttgtgagt ataatcgcgc
    19201 cagtctgaga gggcctatca gtacagaatc tctctgagaa cagagactaa cgatagcagg
    19261 cttttgtgtg tagtctgtac atggcgatga gggaatatag actgtgaaag tggatggaga
    19321 ggaagcgagg cccagttggg aaaggccccg tgctccgtca ggggatcgcc caaagaggaa
    19381 atgccagcac gtggaggcgg ggacatctcc gcatagcttc cccaggcacc cacttcgcaa
    19441 agcctcaccc tgggaccctg aatgcatcta tatccctatc tagggttgta tcggatgttt
    19501 cagagggtat ggggattctt atttattgag ctctgattgt ccggctcaaa aattggggct
    19561 tgacgaacta tcaatcgcca gttcctgtat caattacccc tccaagagcg catcatggca
    19621 gcattcgcgc agtacaccct gtcaacaggg tggtacttta aagatagaga tgagcttgcc
    19681 tcagaagcat ggatgccagt tcctgtggtt ccgtctgtcg ttcaccagga cctacaggcg
    19741 aatggaaagt gcgtaccgtt acggaatctt tcgcggcaca tgtcgctaac gtgcagaccg
    19801 aatgttgttc aggctgaaaa acccatacgt gggatttaat gaactagacg cccgatgggt
    19861 caacgaaaag tcatggacat accgcaagat actgcaaaag ccaactgtcc ttgccggatc
    19921 aagaatcgtt ttggcgttcg atggtcttga tacatttgcc aaagtcaaac ttgacaacaa
    19981 tatcatcctg gagagtagta acatgttcca ggcctatcga gtagatgtca ccaaggccct
    20041 ggactgcggg gatgagcacg ttctggagat tgaatttgat tgtgcgatgt tgcgtgccca
    20101 ggaacttcga aaacaggacc cgaaccacaa ctgggcctct tttaacggag atcctgcgag
    20161 gatgagtgtt aggaaggctc agtatcattg gggctgggat tggggaccgg tcctcatgac
    20221 tgcaggtatc tggcgagcag tgaggttaga agtttactcc acaaggttgg cagatctctg
    20281 gacggagatc aacctagacc ccactcacaa aactgcctcc atttcagcat ttacagagct
    20341 tgaatctgtt gatcttgacc cctcatacaa agtcaaattc acgatcactc tacatgggaa
    20401 gcaaattgct caagcagagg ccacacctca agaggggagg gcaaaggtgg aattcaacat
    20461 agatcagcct tgcctttggt ggccccatgg atatggtgat tccactctct acgaagtctc
    20521 ggcatccttg aacgccgatc aacttgaact ccatagagtt accaagaaga ttggaatcag
    20581 gactgcggag gtcgtgcagc ggccagacaa gcacgggaaa tcattcttct tccgaatcaa
    20641 cggcgtggat atattttgtg gcggttcatg ctggattcct gcagacaacc ttcttcccaa
    20701 catttctccg cagcgatacc gaaaatggat ccagttaatg gttgcgggcc gccaagctat
    20761 gatcaggttt gttcactcgc tcaactgtag atttattact aacaacttgc agagtctggg
    20821 gcggtggttg ctacgaagat gacagtttct acgaagcttg tgatgagctt ggtgttttgg
    20881 tatggcagga cttcatgttc ggatgtggaa attacccaac ctggcccgaa ctgttgaaat
    20941 ctatcgaaca agaggcgatc tacaacgtcc gccgcctgcg ccatcatcca tctattgtag
    21001 tctatgtcgg taacaacgaa gactaccaag tccaggaaca agccggtctc gaatataact
    21061 acgaagataa aaacccagag aactggctaa agaccaactt tccagcccgg tatatctacg
    21121 aagagctgct gccatcggtg gttgagcgtt gttcaccaaa gacgttctac catccaggta
    21181 gtccttgggg tgatggcaaa ataacttctg atcccacagt cggcgatatg caccaatgga
    21241 atggtaatgc tacttccatt taccctcagg agtataccta aaactgacat ttatagtctg
    21301 gcatggcacg caggagaaat accagatatt cgatacgcta ggtggacgat tcaatagcga
    21361 attcggcatg gaggcgtttc cccacctgtc aacaattgaa tacttcgttg agaacgaaaa
    21421 agacaaatac ccccaatcgc atgttctgga tttccataat aaggccgacg ggcacgaacg
    21481 tcgcatcgct acttaccttg tggagaacct gcgaactgct accgacctcg aggtatgtga
    21541 ctacgcaacc aaaccaacca tatacgtgct aattttccaa atagacctac atctacctca
    21601 cccagg
//
