LOCUS       KZ851915.1             37875 bp    DNA     linear   PLN 20-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   KZ851915
VERSION     KZ851915.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 07:38:58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: <126315
            Orig. end    :: >164190
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             join(<1..197,254..322,386..470,525..630,682..754,804..957,
                     1015..1028,1080..1503,1558..>1845)
                     /NRPS_PKS="Domain: Aminotran_1_2 (79-461). E-value:
                     4.5e-73. Score: 238.1. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_237633_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="InterPro:IPR004839"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="PFAM:PF00155"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 340.6; E-value:
                     1.9e-103)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_237633"
                     /note="BUSCO:EOG09262DKA; GO_function: GO:0030170 -
                     pyridoxal phosphate binding [Evidence IEA]; GO_function:
                     GO:0003824 - catalytic activity [Evidence IEA]; GO_process:
                     GO:0009058 - biosynthetic process [Evidence IEA]"
                     /product="PLP-dependent transferase"
                     /protein_id="ncbi_M747DRAFT_237633-T1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 6.9e-06,
                     bitscore: 19.3, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MFSGHRAAFFSTRAIKIQPSLAVTLRPLSTPTLPRQPFSRAMSAT
                     TARPDPFKPAARVAGQRQDVWSIVNEAAAASPVQPIVNMGQGFFGYNPPKFALDAAKEA
                     LDRVECNQYSPTKGRPRLKKAIADAYSPSFGRTLNPDTEVTITTGANEGMLSAFMGFIE
                     PGDEVIIFEPFFDQYISNIEMPGGKIRYVPLHPPKDGATRTSPASEWTIDFEELENTIN
                     DKTKMIVLNSPHNPVGKVFSRAELERIGEICVKHNLIILSDEVYDRLYYVPFTRIATLS
                     PELYERTLTVGSAGKAFYATGWRVGYLVGPEHLIKYVAGAHTRICYSSVSPLQEAAAVA
                     FEQADKVGFWDESRNEMKKKMERFCEVFDELKIPYSDPEGGYFVLANMSSVKLPEDYPF
                     PPHVASRPRDFKLCWFLIHEVGVAAIPPTEFYTDANAHIAEDYLRFAVCKNDDVLETAK
                     ERLRGLKKYIA"
     protocluster    <1..>37875
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[146146:146518](+),
                     [146589:149881](+), [149936:150261](+),
                     [150328:150632](+)}"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(19832..20203,20275..23566,23622..23946,24014..24317)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    <1..>37875
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          <1..>37875
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS-like"
                     /region_number="2"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     mRNA            join(<1..197,254..322,386..470,525..630,682..754,804..957,
                     1015..1028,1080..1503,1558..>1845)
                     /locus_tag="M747DRAFT_237633"
                     /product="PLP-dependent transferase"
     gene            <1..>1845
                     /locus_tag="M747DRAFT_237633"
     aSDomain        join(294..322,386..470,525..630,682..754,804..957,
                     1015..1028,1080..1503,1558..1818)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_237633_Aminotran_1_2.1
                     "
                     /evalue="4.50E-73"
                     /label="M747DRAFT_237633_Aminotran_1_2.1"
                     /locus_tag="M747DRAFT_237633"
                     /score="238.1"
                     /tool="antismash"
                     /translation="PIVNMGQGFFGYNPPKFALDAAKEALDRVECNQYSPTKGRPRLKK
                     AIADAYSPSFGRTLNPDTEVTITTGANEGMLSAFMGFIEPGDEVIIFEPFFDQYISNIE
                     MPGGKIRYVPLHPPKDGATRTSPASEWTIDFEELENTINDKTKMIVLNSPHNPVGKVFS
                     RAELERIGEICVKHNLIILSDEVYDRLYYVPFTRIATLSPELYERTLTVGSAGKAFYAT
                     GWRVGYLVGPEHLIKYVAGAHTRICYSSVSPLQEAAAVAFEQADKVGFWDESRNEMKKK
                     MERFCEVFDELKIPYSDPEGGYFVLANMSSVKLPEDYPFPPHVASRPRDFKLCWFLIHE
                     VGVAAIPPTEFYTDANAHIAEDYLRFAVCKNDDVLETAKERLR"
     mRNA            complement(join(<2338..2819,2883..4541,4627..4697,
                     4745..4783,4949..>5064))
                     /locus_tag="M747DRAFT_351202"
                     /product="hypothetical protein"
     gene            complement(<2338..>5064)
                     /locus_tag="M747DRAFT_351202"
     CDS             complement(join(<2338..2819,2883..4541,4627..4697,
                     4745..4783,4949..>5064))
                     /codon_start=1
                     /locus_tag="M747DRAFT_351202"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_351202-T1"
                     /transl_table=1
                     /translation="MVTQSSLLDRVWLYTHKRSPILLALHPPSQSSLISSEGHLEEQTE
                     PTVQSRRYRYIPNTIMNTNMHPQSLDSVRSGEEAKSENEDSNTRSGAISLIRARTISRS
                     STPRDTQEGCSSEQADDSQQAVSIPRIVVMEPPGDSKAKRNKMKKNKYKKKKLLLGDSE
                     SETSGSQGSGLNGKPTAESNTSNDTSSHMKEIEDLSHSAWMPAKGLNSGGCANKEKPMS
                     GSNVSERCTVDSDKKRDLIESLSKLDIKGKQRVWQVNAVTGNDTLEEINTQRGPQPVDR
                     ARRTVLAPSYATVLSGKRASIEGPSSMPNNSDSLLPTTMEFPKLTDKTSAGQDSSPEAR
                     SGHAKLSPIPEISGEFAGDNSNDIPLSQTDLETAGSSSLDNPISTPVSTVSTGWSSTAL
                     QISPQTTEPSSEPSSSKAVSHRHATSLHHAHPLPPTPPSSTHSHSLSTANATITNAQGT
                     LSAQKPEGFFWQLDSHGFPCAKAHCEKRCNLWDGATVICPRCGPYSEVRYCSRAHLLED
                     IKPHWLYCGQMVFQHPCRETSIPRRVRAGPPLIPCLHHYDMPERHRQAVHFNMNAREGD
                     YFIFTDWLDFVTAGLPGDKTAIRCSNRIMYVVKFDDAAEKDRFRRVLAACLFMTIELPD
                     LTDYLYRLIRDKLRLANAPNHIEPSLRYQFLQEFNVTIQERITGSRHACETDWDGRNRR
                     NCQDPVCRAEYRRLLGSVGGRGYSRMIETLESTYWILRAARTTHPSVKDAMKRMMGEGY
                     AEVAEEDRRAFRRGDGWDGAGSGDMEIEGFNEGDE"
     mRNA            6416..9055
                     /gene="PRM1"
                     /locus_tag="M747DRAFT_295797"
                     /product="plasma membrane fusion protein prm1"
     gene            6416..9055
                     /gene="PRM1"
                     /locus_tag="M747DRAFT_295797"
     CDS             6702..8921
                     /codon_start=1
                     /gene="PRM1"
                     /locus_tag="M747DRAFT_295797"
                     /note="BUSCO:EOG09261VUC; EggNog:ENOG41"
                     /product="plasma membrane fusion protein prm1"
                     /protein_id="ncbi_M747DRAFT_295797-T1"
                     /transl_table=1
                     /translation="MLFSKSGRTIFPLLPPYGVQDPNGVQGRVIPVHPDGSTPYLGLRA
                     RLSQVWLNRWTVLLLLVLARVLMAASSIKTDMNRAKSEALSACTSVESMGDAMVSMPHY
                     LAEGVNELTADGVNAAIDGLKMLLMLTLTGVEELVIFFVKVMYQTYLCLFTLVVHGVVD
                     VGLSLIEDVTDVLNSTVKTVAKDIAKVTETFEDDYNTLISKINGVASLFGGSVPTLNIS
                     SEIDKLENVQLSSSIDKDLQKINDSIPNFNEVMNFTENVIRFPFDEVKKLVNESLGNYT
                     FNASALPVPAKKTLTFCDKNDGINSFFAGATDIILTARKIFIAILVVAAIIACVPMAWQ
                     EIRRWHTMKERSQLVRKEAHDPMDVVYIVSRPHTAAIGIKAASRFSNSRRQILVRWVIA
                     YATSPAALFVLLLALAGLLSCLCQFILLSAVKRTVPELSNEVGDFAEEVVDVLQNTSAQ
                     WANDANKVIQNVDDELNDHVFGWVNTSTGALNDTLNTFVNKTIGVLNDTFGGTLLYEPL
                     LDVFDCLVGLKVESVQKGLTWVSDHAHIDFPLLPNDTFSRGAEGSLNSSDASESFLADA
                     GDETSNKITEVVYKVISALEKALLIEVIIASCILLVWVINAMFGIIRALTLFWGRDKNR
                     GEGGPAPPNSRPNPGSGPDSHGFIDVPLTSLPSHRDADETAARSQPAPRYEVATSQGSS
                     AAVVSSELEYPDEKVGFAGQRNALRVDGVSDLRGSSYVEYGIEKY"
     mRNA            join(<9281..10020,10084..10947,10998..>11346)
                     /locus_tag="M747DRAFT_280227"
                     /product="hypothetical protein"
     gene            <9281..>11346
                     /locus_tag="M747DRAFT_280227"
     CDS             join(<9281..10020,10084..10947,10998..>11346)
                     /codon_start=1
                     /locus_tag="M747DRAFT_280227"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_280227-T1"
                     /transl_table=1
                     /translation="MSQEDAHNSCKIQGWSSNPEDSDHDQCGESDTEKTWFPGDGICPP
                     TSEFLACCRASYQLWAHAASSPRPDDGLLITRITRAFVRMLENVPRFLYHPPKNVEVLG
                     TSGTRLTVQPSLRMRTTEDMDCTQHYKWLDVVQCLGVPVPKSYEMTTMQQQEISLTSAP
                     LKRGHLTSIILAWSYILSCRWVEILQEAGWNASIQHEKGLQIADSFWKLVTQGRWQASV
                     KTAKGTHYSPWMLIESNRNLKLQKCWARSSASLSAFEMLLGSCISEGLEAELLTGLASV
                     LMLLSRNERPWLSPPTSIPKTPTTPASTCSARSHALYKLWGCLDKAMYLSSTRAAIESL
                     IRSAFFDSSVPCDLLGASFSGIREALSSADEFDPQRALHAITNRRPHLSPLWAAEICMD
                     PDTLSYEVLDCLPPICLPAALWTGTMQSFLQVAYRSDEPADLEAKLLRAREFQIAYFCQ
                     PSIPVPETPAPPFGETILNNVSREVETHMAHEHMTRSWQMYWTTKSGAKKPATAQYVLE
                     LVEARMEKDVADYNFDEEFPIKLREAVDEISCCATRRMFNWHREYDGGISLDDGTMSPE
                     TVRCLQAHPWISGPLIDSNKSIQVGGENDHWDDNTQRITIQKEVKGGVSTSDYILEWHK
                     EVERCLGSEDARVSS"
     mRNA            complement(join(12014..13821,13870..15824,15877..16080,
                     16134..16577))
                     /locus_tag="M747DRAFT_280230"
                     /product="xanthine dehydrogenase"
     gene            complement(12014..16577)
                     /locus_tag="M747DRAFT_280230"
     CDS             complement(join(12138..13821,13870..15824,15877..16080,
                     16134..16367))
                     /codon_start=1
                     /db_xref="InterPro:IPR000674"
                     /db_xref="InterPro:IPR001041"
                     /db_xref="InterPro:IPR002346"
                     /db_xref="InterPro:IPR002888"
                     /db_xref="InterPro:IPR005107"
                     /db_xref="InterPro:IPR006058"
                     /db_xref="InterPro:IPR008274"
                     /db_xref="InterPro:IPR016166"
                     /db_xref="InterPro:IPR016208"
                     /db_xref="InterPro:IPR036010"
                     /db_xref="InterPro:IPR036318"
                     /db_xref="InterPro:IPR036683"
                     /db_xref="InterPro:IPR036856"
                     /db_xref="InterPro:IPR036884"
                     /db_xref="InterPro:IPR037165"
                     /db_xref="PFAM:PF00111"
                     /db_xref="PFAM:PF00941"
                     /db_xref="PFAM:PF01315"
                     /db_xref="PFAM:PF01799"
                     /db_xref="PFAM:PF02738"
                     /db_xref="PFAM:PF03450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1293:aldehyde oxidase and xanthine dehydrogenase
                     (Score: 720.5; E-value: 4.1e-218)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_280230"
                     /note="GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]; GO_function: GO:0046872 - metal ion binding
                     [Evidence IEA]; GO_function: GO:0005506 - iron ion binding
                     [Evidence IEA]; GO_function: GO:0009055 - electron transfer
                     activity [Evidence IEA]; GO_function: GO:0051536 -
                     iron-sulfur cluster binding [Evidence IEA]; GO_function:
                     GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence
                     IEA]; GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]; GO_process: GO:0055114 -
                     oxidation-reduction process [Evidence IEA]"
                     /product="xanthine dehydrogenase"
                     /protein_id="ncbi_M747DRAFT_280230-T1"
                     /transl_table=1
                     /translation="MAPGILESPKPTVAASKAVTLAQLTEDWDDTIRFYLNGTKVVLDS
                     INPEVTLLEYLRGIGLTGTKLGCAEGGCGACTVVVSHFNTTTKKLYHASVNACLAPLIS
                     VDGKHVITVEGIGDVKNPHAVQQRLAVGNGSQCGFCTPGIVMSLYALLRNNSAPTEHDV
                     EEAFDGNLCRCTGYRPILDAAQSFTAPKGCGKSLANGGTGCCMDKQNGAGGCCKRSSAD
                     TTDGDGPKFTPPEFIEYTPGTELIFPPQLHKHEFRPLVLGNKKKKWYRPVTLEQLLEIK
                     AVHPDAKIIGGSTETQIEVKFKAMRYSTSVYVGDIPELRQYSLKDDHLEIGANVSLTDL
                     ESICDEALERYGPLRGQPFNAIKKQLRYFAGRQIRNVASPAGNLATASPISDLNPVFVA
                     TNTVLVAMSLGEVIEIPMSQFFKGYRSTALPPDAIIACLRIPVASEKGEYLRAYKQSKR
                     KDDDIAIVNAALRVSLSPSHDVQSVNLVFGGLAPMTVSARNAEAYLAGKKFTNPATLEG
                     TMGALEQDFDLKFGVPGGMATYRKSLALGFFYRFYHDVLSSIQVTDADVDEDVIAEIER
                     AISSGEKDHEASAAYQQKILGKASPHVSALKQATGEAQYTDDMPMMKNELYGCMVLSTK
                     AHARILSVDTSAALDIPGVAHYVDHTDLPNPKANWWGAPNCDEVFFAVDEVTTAGQPIG
                     MILATSAKIAEEGARAVKVEYEELPAILSMEEAIEAESFFEHSRFIKCGDPERAFKEAD
                     YVFTGQSRMGGQEHFYLETQACVAIPKLEDGEMEIWSGTQNPTETQTYVAQVTGVAANK
                     IVSRVKRLGGGFGGKETRSVQLAGICATAAAKAKLPVRCMLNRDEDIATSGQRHPFFCR
                     WKVGVTKEGKLLAFDADVYANGGHTQDLSGAVVERALSHIDGVYNIPNMHVRGRICKTN
                     TVSNTAFRGFGGPQGMFFAECMVSEVADHLQIPVEQLRWQNMYKPGDKTHYNQELKDWH
                     VPLMYKQVMDESSYEERRKAVEEYNKKHKWSKRGMALIPTKFGISFTALFLNQAGALVH
                     IYHDGSVLVAHGGVEMGQGLHTKMTMIAAEALGVPQSNVFISETATNTVANTSSTAASA
                     SSDLNGYAIYNACEQLNERLKPYREKMPGATMKDLAHAAYFDRVNLSAQGYYRTPDIGY
                     VWGENKGQMFFYFTQGVTAAEVQIDTLTGDWTPLRADIKMDVGRTINPSIDYGQIEGAF
                     IQGQGLFTTEESLWHRASGQIFTKGPGNYKIPGFRDIPQIFNVSLLKDVEWENLRTIQR
                     SRGVGEPPLFMGSAVFFAIRDALKAARQQWNVKEVLRLESPATPERIRVSCADPIIERA
                     RVVPKEGEKSFFVAI"
     mRNA            complement(join(16851..17134,17257..19346))
                     /locus_tag="M747DRAFT_280232"
                     /product="hypothetical protein"
     gene            complement(16851..19346)
                     /locus_tag="M747DRAFT_280232"
     CDS             complement(join(17059..17134,17257..18956))
                     /codon_start=1
                     /locus_tag="M747DRAFT_280232"
                     /note="SECRETED:SignalP(1-24); EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_280232-T1"
                     /transl_table=1
                     /translation="MIPHRSTALITIIVFVALVLVIFSSSPTTDPSTGEEVSGPAKYVP
                     HPKLPSLNNLHLPSFHPTVHTPPEPQPNSTSGESKWFSDWSWINPFSSSITLDENRSVL
                     PPLRNRPFIYTYYEPNKGNDREEDNADAQLLLAWRRAWFAQGFRPVILGPGEAMNNQLY
                     ELVQPLNLKPELESELFRWLAWGHMGDGMLADWHCFPMARYDNALLTYLRRGTDPALIT
                     RFDGFGNALFAGEKSRINDAIKEAMNKVDDKSTSLIDLLPAEFFKVEEPNALALYDSTA
                     ITSHYPTVAEKIVSSPTAGRLALAELINAHLHNTFQNSFPAGIAVLKPFPEHTTALVEP
                     ALRLAKALVQCPGSPVPRSCPPNLPKCHPCDAEKPMQVSQPATYRNTTQVFTIGTLPHP
                     FTLISLQQDSTEVTTRHIRRETDRDVWLAEVTKEHLGTDIGGSARAVVFKRAVADDAVV
                     GTSLWMTVESLPPQAGQSLPSELLDEFEWQFGFKIPRDGKVDAKNEEEKKESIQQANPS
                     EQGVEKEYGILKQAREFLKGKGTNRICITDVAEAWNLADTEVWRFVRAYRARSVVERKK
                     WEEEEKDFIGAKPKV"
     mRNA            join(19738..20203,20275..23566,23622..23946,24014..24617)
                     /gene="LYS2"
                     /locus_tag="M747DRAFT_259919"
                     /product="large subunit of alpha-aminoadipate reductase"
     gene            19738..24617
                     /gene="LYS2"
                     /locus_tag="M747DRAFT_259919"
     CDS             join(19832..20203,20275..23566,23622..23946,24014..24317)
                     /NRPS_PKS="Domain: AMP-binding (268-736). E-value: 2.6e-73.
                     Score: 238.6. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_259919_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (877-949). E-value: 1.3e-15. Score:
                     49.1. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_259919_PCP.1"
                     /NRPS_PKS="Domain: NAD_binding_4 (1011-1260). E-value:
                     9.3e-74. Score: 239.3. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_259919_NAD_binding_4.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /codon_start=1
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="InterPro:IPR010080"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="InterPro:IPR014397"
                     /db_xref="InterPro:IPR020806"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="InterPro:IPR036736"
                     /db_xref="InterPro:IPR042099"
                     /db_xref="PFAM:PF00501"
                     /db_xref="PFAM:PF00550"
                     /db_xref="PFAM:PF00668"
                     /db_xref="PFAM:PF01073"
                     /db_xref="PFAM:PF01370"
                     /db_xref="PFAM:PF07993"
                     /gene="LYS2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     252.9; E-value: 8.2e-77)"
                     /gene_kind="biosynthetic"
                     /locus_tag="M747DRAFT_259919"
                     /note="BUSCO:EOG092603D0; GO_function: GO:0031177 -
                     phosphopantetheine binding [Evidence IEA]; GO_function:
                     GO:0004043 - L-aminoadipate-semialdehyde dehydrogenase
                     activity [Evidence IEA]; GO_function: GO:0003824 -
                     catalytic activity [Evidence IEA]; GO_process: GO:0009085 -
                     lysine biosynthetic process [Evidence IEA]"
                     /product="large subunit of alpha-aminoadipate reductase"
                     /protein_id="ncbi_M747DRAFT_259919-T1"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-98, bitscore:
                     323.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-12, bitscore:
                     42.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 4.2e-73, bitscore:
                     239.3, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MAVESVSLQERLERWAQRLQNLTVSPLTRDYPDNQKQELPKRAIE
                     AFESIQLSKETQSDLQKISGSSSGFTVFLTAFIVLVARLTGDEDIAVGTSSSDDGRPFV
                     LRVPIEASETFLQLYAKVQKAFEQGSAEIVPLGSLRSYIQEKSQSERSPVLFRFAAYDA
                     PAASQDYPANTFETTDLVVNIAPISASDGSTTQAELGAYYNQRLFSSSRISTILKQLAR
                     LVENATSNPEQAIGRIDFMTEDQLALLPDPTSDLNWSNFRGAIHDIFAANAEKHPERLC
                     VVETKSERSPHREFTYKQINEASNILGHHLVQSGVERGEVVMVYAYRGVDLVVAVMGIL
                     KAGATFSVIDPAYPPERQCIYLDVARPRALINIEKATKDAGELSDVVRSFINENLELRT
                     EVPALALRDDGSLVGGSINGQDVLANQVPLKAKSVGVVVGPDSTPTLSFTSGSEGRPKG
                     VKGRHFSLAYYFPWMSETFKLTPNDRFTMLSGIAHDPIQRDIFTPLFLGAQLLVPARED
                     IQNEKLAEWMREYGATVTHLTPAMGQILVGGASAQFPSLHHAFFVGDILIKRDCRSLQG
                     LAPNVNIVNMYGTTETQRAVSYFEIPSYSSDEGYLDTMKDVIPAGRGMLDVQMLVVNRF
                     EPSRICAIGEVGEIYVRAGGLAEGYLGSPELNQKKFLNNWFVDNQTWVQKDQAKADSAN
                     EPWRQFYQGPRDRLYRSGDLGRYTPSGDVECSGRADDQVKIRGFRIELGEIDTHLSRHP
                     LVRENVTLVRRDKFEERTLVSYFVPDMSKWAAWLQEKGLEDDDSAEGMVGMLRRFRPLR
                     DDIRDLLRTKLASYAVPTVFIPLKRMPLNPNGKIDKPALPFPDTAELSAAAPRRKSSVV
                     QALSETEQALASIWASRIPNLTARMIGPDDSFFDLGGHSILAQQMFFDIRRKWRGIDVS
                     MNAIFRSPTLRGFAAEIDRLQNFESFASNDDKTAAKADASATPDELDDEYSKDARKLAE
                     TSLPASFPTRTEPLLSSEPTIFLTGATGFLGAHILRDLLTRKSPMAKVVTLVRGKTDEQ
                     ALERIRSTCRAYGFWDEAWTSRLQCVCGNLGEPRFGFSDALWDDLTKRVDAVIHNGALV
                     HWVYPYSTLKPANVQGTIDALKLCASGKPKQFSFVSSTSVLDSDHYVSESERIVAAGGA
                     GISEEDDLEGSAVGLGTGYGQSKWAGEYLVREAGRRGLKGTVVRPGYVLGDSKTGTTNT
                     DDFLIRMIKGCIQLSSRPNINNTVNMVPVDHVARVVIAAAFQPPCTPIGVAQVTGHPRL
                     RFNQFLGALQLYGYDVPQVDYVPWSKSLEQYVNDGQHDDPESQHALMPLYHFVTSDLPS
                     NTKAPELDDVNAAASLRADAAWSGIDASAGAGVTEELVGLYASYLVQTGFLPPPSAASA
                     AARPLPTTQLSEDQKKALSNVGGRGGSS"
     aSDomain        20707..22110
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_259919_AMP-binding.1"
                     /evalue="2.60E-73"
                     /label="M747DRAFT_259919_AMP-binding.1"
                     /locus_tag="M747DRAFT_259919"
                     /score="238.6"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FAANAEKHPERLCVVETKSERSPHREFTYKQINEASNILGHHLVQ
                     SGVERGEVVMVYAYRGVDLVVAVMGILKAGATFSVIDPAYPPERQCIYLDVARPRALIN
                     IEKATKDAGELSDVVRSFINENLELRTEVPALALRDDGSLVGGSINGQDVLANQVPLKA
                     KSVGVVVGPDSTPTLSFTSGSEGRPKGVKGRHFSLAYYFPWMSETFKLTPNDRFTMLSG
                     IAHDPIQRDIFTPLFLGAQLLVPAREDIQNEKLAEWMREYGATVTHLTPAMGQILVGGA
                     SAQFPSLHHAFFVGDILIKRDCRSLQGLAPNVNIVNMYGTTETQRAVSYFEIPSYSSDE
                     GYLDTMKDVIPAGRGMLDVQMLVVNRFEPSRICAIGEVGEIYVRAGGLAEGYLGSPELN
                     QKKFLNNWFVDNQTWVQKDQAKADSANEPWRQFYQGPRDRLYRSGDLGRYTPSGDVECS
                     GRADDQVKIRG"
     CDS_motif       21244..21288
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_259919_0001"
                     /evalue="4.50E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="M747DRAFT_259919"
                     /score="13.2"
                     /tool="antismash"
                     /translation="FTSGSEGRPKGVKGRH"
     CDS_motif       21829..21915
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_259919_0002"
                     /evalue="2.50E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="M747DRAFT_259919"
                     /score="26.3"
                     /tool="antismash"
                     /translation="IGEVGEIYVRAGGLAEGYLGSPELNQKKFL"
     CDS_motif       22081..22137
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_259919_0003"
                     /evalue="2.10E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="M747DRAFT_259919"
                     /score="35.7"
                     /tool="antismash"
                     /translation="GRADDQVKIRGFRIELGEID"
     aSDomain        22534..22749
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_259919_PCP.1"
                     /evalue="1.30E-15"
                     /label="M747DRAFT_259919_PCP.1"
                     /locus_tag="M747DRAFT_259919"
                     /score="49.1"
                     /tool="antismash"
                     /translation="EQALASIWASRIPNLTARMIGPDDSFFDLGGHSILAQQMFFDIRR
                     KWRGIDVSMNAIFRSPTLRGFAAEIDRL"
     aSDomain        join(22936..23566,23622..23737)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_259919_NAD_binding_4.1
                     "
                     /evalue="9.30E-74"
                     /label="M747DRAFT_259919_NAD_binding_4.1"
                     /locus_tag="M747DRAFT_259919"
                     /score="239.3"
                     /tool="antismash"
                     /translation="LTGATGFLGAHILRDLLTRKSPMAKVVTLVRGKTDEQALERIRST
                     CRAYGFWDEAWTSRLQCVCGNLGEPRFGFSDALWDDLTKRVDAVIHNGALVHWVYPYST
                     LKPANVQGTIDALKLCASGKPKQFSFVSSTSVLDSDHYVSESERIVAAGGAGISEEDDL
                     EGSAVGLGTGYGQSKWAGEYLVREAGRRGLKGTVVRPGYVLGDSKTGTTNTDDFLIRMI
                     KGCIQLSSRPNINNTVNMVPVDHVARVV"
     mRNA            complement(join(24812..25160,25224..25296,25348..25873))
                     /locus_tag="M747DRAFT_331514"
                     /product="hypothetical protein"
     gene            complement(24812..25873)
                     /locus_tag="M747DRAFT_331514"
     CDS             complement(join(25035..25160,25224..25296,25348..25733))
                     /codon_start=1
                     /locus_tag="M747DRAFT_331514"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_331514-T1"
                     /transl_table=1
                     /translation="MSTVVTTAPPVQTMSLQAVSHSGSSDEELLQLFRRVTITSSDGHD
                     VSEIQIKKAFQQEISRPLGRQMLEASLAHANGCSCYHWNYHDRISGKVNISRVDLTFDL
                     TSKSMGQAVKGEAAGFYRPNSAFINATVYYDDQQYLQGNQSVQIYMDGSKFIIDFFTTD
                     QSDKPVARIVQNASSFTFQGTDTGDATWGTS"
     mRNA            25888..26331
                     /locus_tag="M747DRAFT_40707"
                     /product="hypothetical protein"
     gene            25888..26331
                     /locus_tag="M747DRAFT_40707"
     CDS             26042..26290
                     /codon_start=1
                     /locus_tag="M747DRAFT_40707"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_40707-T1"
                     /transl_table=1
                     /translation="MDHISAVLEHSDLTIASLMSSLGMNSAMRCEAACDGCLHLRKHDF
                     GVYSPASHILISKVRSCRHGHEAIGSQPIQEQALLFP"
     mRNA            complement(26332..26723)
                     /locus_tag="M747DRAFT_40708"
                     /product="hypothetical protein"
     gene            complement(26332..26723)
                     /locus_tag="M747DRAFT_40708"
     CDS             complement(26372..26638)
                     /codon_start=1
                     /locus_tag="M747DRAFT_40708"
                     /note="SECRETED:SignalP(1-26)"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_40708-T1"
                     /transl_table=1
                     /translation="MWLLRCANCHGYVYLIMSSIILIGDALFSCPSTDTVERISLDSLY
                     PSQVQTRPSVHQIPARRCDPSSKQTGASIWLAALLHVRNYRSL"
     mRNA            join(28089..28254,28331..28381,28448..28598,28655..29011,
                     29067..29647)
                     /locus_tag="M747DRAFT_295804"
                     /product="Aldo/keto reductase"
     gene            28089..29647
                     /locus_tag="M747DRAFT_295804"
     CDS             join(28350..28381,28448..28598,28655..29011,29067..29573)
                     /codon_start=1
                     /db_xref="InterPro:IPR023210"
                     /db_xref="InterPro:IPR036812"
                     /db_xref="PFAM:PF00248"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     330.3; E-value: 1.7e-100)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_295804"
                     /product="Aldo/keto reductase"
                     /protein_id="ncbi_M747DRAFT_295804-T1"
                     /transl_table=1
                     /translation="MATNNDMEYVRLGNSGLKISKIILGAMSYGAKQWQDWVLDEEEAL
                     PLIEHAYKRGINTWDTADVYSHGRSEEVIGKALKKFSIPRNRVVILTKCYFGVDDQGNF
                     PPISASGANDGGFVNRVGLSRKHIFDAVDASVERLGTYIDVLQIHRLDRDTPREEIMRA
                     LNDVVESGKVRYIGASTMAAWEFQTLQNIAARNGWHQFISMQNYHNLIAREEEREMIPY
                     CRDTGVGLIPWSPMARGVLTRPWGSRSTVREATDGALKFLIRSRETESDKAIVDRVEEI
                     AKKRGISMAQVAIAWSLSHPNENPILGLNSKERIDEAVAATKVKLTDEEIKYLEEPYIP
                     KAITALER"
     mRNA            complement(30383..32472)
                     /locus_tag="M747DRAFT_40750"
                     /product="hypothetical protein"
     gene            complement(30383..32472)
                     /locus_tag="M747DRAFT_40750"
     CDS             complement(30472..32235)
                     /codon_start=1
                     /locus_tag="M747DRAFT_40750"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_40750-T1"
                     /transl_table=1
                     /translation="MLFNLGLTADAAAAHENEYPGLPSETQIPSPTRHSSPAISFASLP
                     SWGLGSIYNRRKPTEPETTQRTMPRKAAIDTLSSSDDERSTVTPVLAPSRIARSQSVRK
                     QSSRPKTSYQLAHPAAHARHRRLKLRPKLLLQLQRVSQTPRPLPLLDVLPSTVFLPPLA
                     RKFPMIFRGKKGLGPNDLIVVTSDLYERAPGDNGDRSLSSDDEGGEQREVVATICQLFR
                     DDALSKGKAEICLNHGPVWEATPLANGSYEFVANTDDGIQVLRWVLRGGRNRRVSAPPG
                     FSQEDSKRFTFSVINPSTRRHPVVGTMTRNHLEVYDEYSIPTTPGIAGSPTSAMSVLSD
                     FSEMDDPLDRKVLKTDNDLRMLIIITSIWVAFREGWSHNFTYDDSALAINTKTMCPSRH
                     SSPTAIRSETDRFTERDDGHDDVPPLNGRRHRLSTSSYVPSQSTVSDRSTTFGSLSRRS
                     NSTGAAFIERTNRRASGSNGRLTRHSTLSSPREQRQDETVEAKPARQDSKSRRLFSHRK
                     SDVQDFKMTASPDQAIDGSRGYENNQSRQADSFRDKGIDSPADSAPSKGKRRHRISSLF
                     EYIIRKTGHHH"
     mRNA            join(<36343..36694,36763..37381,37437..>37875)
                     /locus_tag="M747DRAFT_305584"
                     /product="GPI mannosyltransferase 2"
     gene            <36343..>37875
                     /locus_tag="M747DRAFT_305584"
     CDS             join(<36343..36694,36763..37381,37437..>37875)
                     /codon_start=1
                     /db_xref="InterPro:IPR007315"
                     /db_xref="PFAM:PF04188"
                     /locus_tag="M747DRAFT_305584"
                     /note="CAZy:GT76; BUSCO:EOG09262GLP; GO_function:
                     GO:0004584 - dolichyl-phosphate-mannose-glycolipid
                     alpha-mannosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006506 - GPI anchor biosynthetic process
                     [Evidence IEA]"
                     /product="GPI mannosyltransferase 2"
                     /protein_id="ncbi_M747DRAFT_305584-T1"
                     /transl_table=1
                     /translation="MSSSLSSPATSRPSLLNPRQPIKALTVAFCLWKALVYLVIISCPG
                     LGYDTSTSHLYHSHSRPDVTSEDITYAHLPIPLKFVRWDSVYFLHIAENGYIFEQEWAF
                     GYGYTRVLAYIATALQRLIGPSGAARTAVVATALSHITHYLAVLALYRLSVNVFGRDTA
                     TQRLICFLSAVLHVICPAGAFLSAPYGESLFSFLNITGFYVYSSSFLDSKAGKRLSGDV
                     KLLVAAILFSAATAVRSNGILSGILYAYDALLQLRRVWCQRLSIDACAHLSVIIISGCV
                     IALGLVVPQVVAYSTYCVEDDISRPWCQWLVPSIYRYVQGHYWSVGFLRYWTVSNIPLF
                     ILAMPMLAILCRSSLWALDVAVPFIFPRALSGVDQASSSATTASLLLRLAVPQGLLALM
                     ALTSYHVQIINRISSGYPLWYWYLAYLVSGNWGQMRPSLQDSRTFTVAVRGMVAYALIQ
                     AILFGSFLPPA"
ORIGIN
        1 atgttctctg gccaccgcgc tgcttttttc tctaccagag ccatcaagat tcagccctcg
       61 ctggccgtta ccctgcgccc cttgtcaact cctacactac cccgccagcc attctcccga
      121 gcgatgtcgg ccaccacggc tcgtcccgac cctttcaaac cggcggccag agtcgctggc
      181 cagagacaag atgtctggtg cgatgcgcat gaatgttcac attgctgctt ctcagtgtct
      241 gaccggatcg caggtccatt gtcaatgaag ccgccgctgc ctcccccgtc cagcccatcg
      301 tgaacatggg acagggtttc ttgtgagtga taaatcgccg aagatggatg actcggagtt
      361 cctgaccttt tttctacttg cgcagtggct ataaccctcc caagttcgcc ctggatgccg
      421 ccaaggaggc ccttgaccgt gtggagtgca accaatactc ccccaccaag gtacagccgg
      481 attgcgacat attcataccg gaacacttgc tcaccttcga ttagggacgc ccgcgtctca
      541 agaaagccat cgccgatgcc tactcgcctt cctttggccg gactctcaac ccggacaccg
      601 aagttaccat caccacaggt gcaaatgaag gtgggacata ctctgttgcg tgcgtgactg
      661 gtagctgacg agttgtccaa ggtatgctga gtgcgttcat gggcttcatc gagcccggcg
      721 acgaggtgat catctttgaa cctttcttcg accagtgagt cacttctatt cttgccatgc
      781 gaacccttct aatggcccca aaggtacatt agcaacatcg agatgcccgg aggaaagatc
      841 cgctatgtcc ctcttcaccc tcccaaggat ggcgcgacga ggacttcccc cgcctccgag
      901 tggacgatag actttgagga gttggagaat accatcaacg acaagaccaa gatgattgta
      961 agcctgacct tacttcctag ttcatactgc tatagtacta accatcctca ttaggtcctg
     1021 aactccccgt aagtaaccta acaagtgacc atctcaagcc gcaaactgac caagcacagt
     1081 cacaaccccg ttggcaaggt cttctcgcgc gctgagctgg agcgcattgg agagatctgc
     1141 gtgaagcaca acctgatcat cctctccgac gaagtctacg accgcctcta ctacgtccct
     1201 ttcaccagaa tcgctaccct gtctcctgag ctctacgagc gcactctcac cgtcggctct
     1261 gccggcaagg ccttctacgc cactggctgg cgagtaggat acctcgtcgg tcccgagcat
     1321 ttgatcaagt acgtggccgg cgcgcacacc cgcatctgct acagcagtgt gtctcctctt
     1381 caggaggctg ccgccgttgc tttcgagcag gccgacaagg tcggattctg ggacgagagc
     1441 cggaacgaga tgaagaagaa gatggagcgt ttctgcgaag tctttgacga gctcaagatt
     1501 cccgtgagta ttccattgct agaatttctc cgggcctgaa ctaaccccag ctcgcagtat
     1561 tcggaccccg agggaggcta cttcgttctt gccaatatgt cttcggtgaa gcttcccgag
     1621 gactacccat tccctcctca cgttgccagc cgtcctcgtg acttcaagct gtgctggttc
     1681 ctgatccatg aagtcggtgt ggcagccatc cctcccactg aattctacac tgacgccaat
     1741 gcacacattg cggaggacta tctccgcttc gctgtctgca agaatgacga tgtgctggag
     1801 actgccaagg agagactgcg cggtctgaag aagtatattg catgagcgtt tcaacatgtc
     1861 tgattaatat gacgggctag catagagcgg gagtctgatc ttgccttcaa cggctgatta
     1921 aaaactatat aggaagaata gaggactaaa acagtctgtt tggcacacaa gtcaattcca
     1981 tttattcttt atcatgatat cgcacattcg ttcttcatgt atgtcacatt accaacaact
     2041 aaatgagcgt atctcaacca tattacacaa tgaaatccac ctcacagact atgcatcgta
     2101 tcaacccgag tcccctattc cccccgcctt tgcctcaaat tccctgctcc agagcaacaa
     2161 attcaaagcc gaaaacagaa agaaagaaaa gagaccacgg caggtagcca gatagacaca
     2221 actcaacgaa ccagcgtcat gtcagcatca catcctgccc accctaccat catcatcctc
     2281 gggccaaaca acggaaccca gtacctatct tccacactcc cctcccctac tcactcacta
     2341 ctcatccccc tcattaaacc cctctatctc catatcaccc gaacccgccc catcccaccc
     2401 atcccccctt ctaaaggccc gtctatcttc ctccgccacc tccgcatacc cctcccccat
     2461 catacgtttc atcgcatcct tcacactagg gtgggtcgtc ctggctgccc tcagaatcca
     2521 ataagttgac tcgagcgtct caatcatccg actgtatcct cttccaccaa cggatcctag
     2581 cagccgacga tactcagccc gacacaccgg atcctgacaa ttacggcggt ttcggccgtc
     2641 ccagtctgtt tcacaggcgt gacgagagcc agtgatgcgc tcttggatgg tcacattaaa
     2701 ttcttgcagg aattggtagc gcagggaggg ttcaatgtgg ttgggagcgt tggccaggcg
     2761 cagtttgtcg cggattagac ggtaaagata gtcggtcaga tcagggagtt cgatggtcac
     2821 tatgtatttc ggggttggtt agttgtctgt aaattagaag aggaagaagg tagggatctc
     2881 actaaagagg caagccgcca gaacacgacg gaatcgatct ttctctgccg catcatcaaa
     2941 tttaaccacg tacattattc tattcgaaca tcgtatagcc gttttatcac ctggtagtcc
     3001 ggcggtaaca aaatccagcc agtccgtgaa gatgaagtaa tcgccttctc tggcattcat
     3061 attgaagtgc acggcttggc gatgacgctc cggcatgtcg tagtgatgca ggcacgggat
     3121 gagaggaggt ccagcgcgga ctcgtcttgg gattgaggtt tcacgacatg ggtgttgaaa
     3181 taccatctgt ccgcagtaga gccagtgagg tttgatgtcc tcaagtaggt gggctctact
     3241 gcaataccgt acttcggagt agggcccgca tcgtggacag atcactgttg ctccgtccca
     3301 gaggttgcag cgtttctcgc agtgggcttt ggcacagggg aagccgtggc tgtcaagttg
     3361 ccaaaagaac ccctctggtt tctgggcgga gagggtgccc tgggcgttag ttatggtagc
     3421 gttggctgtc gacagggagt gggaatgggt gctacttggg ggtgtgggtg gtaggggatg
     3481 ggcgtggtga agactagtgg cgtggcgatg gctgactgcc ttggacgagg atggttcaga
     3541 agacggctca gtcgtttgtg ggctgatttg cagtgctgtg ctgctccagc cagtggatac
     3601 tgtggacaca ggggtcgaga ttgggttgtc aagtgaactg gaacctgcgg tttctaggtc
     3661 cgtttgactg agcggtatgt cgttggagtt atcacctgca aattcacctg atatttccgg
     3721 aataggcgag agctttgcat gaccggagcg tgcttcagga ctgctatcct gtccggcgga
     3781 agtcttgtct gtgagtttgg ggaattccat ggtcgtcggt aggagggaat cactgttgtt
     3841 tggcatagaa gatggaccct cgatactggc acgttttcca gaaaggaccg tggcatatga
     3901 aggagcgagc acagttcttc tcgccctgtc caccggttgg ggaccacgct gtgtatttat
     3961 ctcctccaat gtatcgttgc ctgtgactgc gttcacttgc cagacccgct gcttgccttt
     4021 gatgtccaac ttgcttagtg actctatcaa atctcgcttc ttgtcactgt ccactgtaca
     4081 tctctcagac acattgctgc ctgacatggg cttttcttta tttgcacagc cgccagagtt
     4141 caggcctttg gctggcatcc aagcagagtg agacaagtcc tctatttctt tcatatgaga
     4201 cgaagtatca ttcgaagtat tcgattccgc ggtaggctta ccgttcaatc cagagccctg
     4261 gctcccagaa gtctcgcttt cggaatcacc tagcaggagt ttcttcttct tgtacttatt
     4321 cttcttcatc ttattccttt tggcctttga atccccagga ggttccatca ccacaatccg
     4381 gggaatcgaa acagcctgtt ggctgtcgtc agcttgctcg ctagaacagc cttcttgggt
     4441 atcccttggt gttgatgatc gagaaatagt ccgcgcacgt atgaggctta tggcgccgga
     4501 ccgcgtgttg ctatcttcgt tctcactctt cgcttcttct cctgcatcat ggaaacttgt
     4561 cagtatgtct tcctgcattg tgtatgtgga tagaggaaag gatagatgcg ttcaggcttg
     4621 gctcacctga acggacacta tccaagcttt gtgggtgcat atttgtgttc atgatggtgt
     4681 tggggatgta tctgtacctg ttgttcccgt gaccagacaa gcgagatgaa gtgaatatgc
     4741 tcaccttctc gactgcactg ttggttctgt ttgctcttcc aagctatgga ggcggtctta
     4801 gttgtgcaaa ttcattcaac aagtgtttct tcaagtgatg gtgataatcc agaaagggac
     4861 gctacaacat cagttcactt ctttcactgg atcttctggc tagcagacct ggcatattgc
     4921 atacagagga ctttcatgtc agtcttactg cccctcgcta gatataaggc tagattgtga
     4981 gggaggatgc aacgccagca gaatgggaga tcgtttgtga gtgtacagcc agactctgtc
     5041 taacaggcta ctctgcgtga ccatggtgcg tgccttgaca atgactacta acgctattta
     5101 tgtaaatacc tatctaatag ggaacaagta ataacagacc tctgtgccgc aatacatctg
     5161 ggaattcgct tactccgtac tttggcacag ggttgtaggg agacatgcga taaatctgca
     5221 gaccagcctg cggaatgcca caaccataag atacttatgc caccacgaag cggaaccgac
     5281 cgggatatat tatacactgc tctattattg atggtcaatg ttcttcaatg cctcagacat
     5341 cacaatcagt atacagggag acgcgcagat caggaaggta gagaacattt gggttgggca
     5401 gacatcactc tgtctggcag gtgaatctcc ttctactgtc atatgatcat tccattcaga
     5461 accattactg cctacagcaa gctttcttgt agtgactcgt ctcattgcag gagcaaatag
     5521 gagtgctagt aggaaaggca tggcgggtat atgagacact cctgattcag atgtgccagt
     5581 gtatgctaat tcattgctgt cactcacacc agatcttcaa aagagtagaa cccgcagcat
     5641 cattcaatgt gaagatgtct aaacagctca gaaacacggt tgccttcatc tggtttgctt
     5701 gtgggcgttg gacatcacgt gcccgttcat ttcatccaga atccaaacgg ccaacccaac
     5761 ttggaacttc tcttcaaccg ccctccttct gtcgtccatc aggggatata tttagaacct
     5821 cgacgtgagt caaaaataaa agattagctt caagttttgt caaaatctgc agctctgaac
     5881 cagtcaagtg ttcaataata gacggatctt ccccttccta gcagcaacat gcaacgggaa
     5941 gcgccgccaa cccccagggc atcaagcaaa gagccattag gatcaggctt cactgtttga
     6001 aactacctaa ccgcctctcc tggtgcatct tgcaatgttg tggggtctag ttgtgctgga
     6061 tcgcggattg ggctacagcg ccgtatccta agcgccgaca cggtacctat atttggctgg
     6121 cctgcagaac tctgaagaac tcaccggcat aggctctacc tacagacact gcgctagatg
     6181 aaacttatcg tgcagatcga cccgatcagc tgcagccttt ggccttatta tttgctatcc
     6241 ttgttgacgc tggccgctct tactggctgc cgttggccgt gtcttcaacc tgtctttgtc
     6301 tcagctatta ttgacctggt cacaatggaa gtcggtctgt tgactctctc gcccataata
     6361 aggcggggat atcctcctta ttgtgacatt gctattgatt ctacttcttt catctattgt
     6421 tcttaggtgt tttttttttt tgtttctacc cccaccgtac agcttttttt aaatctatag
     6481 tttggtcatg cagtacggct tctcaacaat tgcatctggt tcatttgaat aattactgct
     6541 ggtcaggatt gttctttctt tgacatctcg tctaccaact ttctataccc tctgtgatag
     6601 acctccttta tttgcacgat cctcaacagc tggactcact tggattttac aaactcattc
     6661 ctccacagaa tcactcccta cacatatagc gtattttcga catgttgttt tcaaaatccg
     6721 gtcggaccat ctttccactg ctaccaccct atggggttca agatcccaac ggcgttcaag
     6781 gtcgagtcat ccctgtacac cctgatggct cgacacctta cctaggcctg cgggcgcgcc
     6841 tttcccaagt atggcttaac cgctggaccg ttttgctgct gctagtcctt gcccgagtgc
     6901 tgatggctgc ctcgagcata aaaacggaca tgaatcgagc caaaagcgag gccctttcgg
     6961 catgcacaag cgtggaatct atgggcgatg ccatggtctc tatgccccat tacctggcgg
     7021 aaggggtcaa tgagctcaca gcagatggtg tcaatgcggc aattgatggc ctaaaaatgc
     7081 tcctcatgct taccttgact ggcgtagagg agttggtgat tttcttcgtc aaagtgatgt
     7141 accagacata tctgtgcttg ttcacgctcg tcgtacatgg tgtggttgat gttggactca
     7201 gcttaatcga agatgtaaca gacgttctga attccacggt caagactgtg gcgaaggata
     7261 ttgctaaggt caccgagacg tttgaggacg actacaatac tctgatatcg aagataaacg
     7321 gggttgccag cttattcgga ggatcagttc cgaccctgaa tatcagcagc gaaatcgaca
     7381 aactggagaa tgtacagctg tcttcgtcca tcgataagga tctccagaag attaacgact
     7441 ccatcccaaa tttcaacgaa gtcatgaact tcactgagaa tgtgattcgt tttcccttcg
     7501 atgaagtcaa aaaactggtc aacgagtcac taggcaatta cacttttaat gcctccgcac
     7561 tccctgtccc tgcgaagaag acactgacgt tttgcgataa aaacgatggg atcaactcat
     7621 tttttgccgg agcaactgat ataatcctaa ccgcccgcaa gatatttatc gccattttgg
     7681 tcgtcgctgc catcatcgct tgcgttccca tggcctggca ggagattcgg cgctggcaca
     7741 cgatgaagga gcgctcccaa cttgttcgca aggaagctca tgatcccatg gacgtcgttt
     7801 acatagtctc cagacctcac acggccgcaa taggtatcaa agccgccagt cgattcagca
     7861 acagccgcag acagattctt gtgcgctggg tgatcgcata tgcgacctcc cccgcagcct
     7921 tattcgtcct ccttctcgca ctggctgggc ttctctcatg cctctgccag ttcatccttc
     7981 tcagcgccgt caagaggaca gtgccggagc tctccaacga agtaggcgac tttgccgaag
     8041 aggttgttga tgtcttacaa aatacatctg ctcaatgggc caacgatgcc aacaaagtca
     8101 tccaaaacgt tgacgatgag ctcaacgatc acgtgtttgg ttgggtcaac accagcaccg
     8161 gcgctttgaa tgacacgctg aatacctttg tcaacaaaac aatcggggtc ctcaacgaca
     8221 cctttggtgg aaccctactc tatgaacctc ttctcgacgt ctttgactgc ttggttggcc
     8281 tcaaagttga aagcgtccag aaaggcctta cttgggtttc cgatcatgcc cacatagact
     8341 tccccctcct ccccaacgac accttttcgc gcggtgcaga agggagtctc aacagttccg
     8401 atgcatcaga gagcttcctc gccgacgccg gtgacgagac atccaacaag atcaccgaag
     8461 ttgtgtacaa ggtcatcagc gctctcgaga aggctctcct aatagaagtc atcattgctt
     8521 catgcatcct tctggtctgg gtcataaatg ccatgtttgg catcatccgc gccctaacac
     8581 tcttctgggg ccgggacaag aaccgtggtg agggcggacc tgctcctccc aattcacgac
     8641 cgaacccagg ctctggaccg gactcgcatg gtttcatcga tgtgccccta acttctcttc
     8701 cgagtcaccg tgacgccgat gagactgctg cgcgctcgca gccggcaccc cgatatgaag
     8761 ttgcgaccag ccagggaagt tctgccgccg tggtgagcag cgaattggag tatccggacg
     8821 agaaagtcgg gttcgcaggc cagcgcaatg ctcttcgagt ggatggggtg tcggatctac
     8881 gcgggagcag ctatgtggag tatggaatag agaagtattg atctgctggc ctattcccta
     8941 ttcatggtga ttcgaactcg ccgtcctacc aactttttgt ttcttagcca gctcgtactc
     9001 cctcgcactt tccttgagcg tctaccatat acccatagac cataattcta actcaataca
     9061 ctctttaatc cagcccgtac aatatctaga atcatctcag gtcagtccat gcgctgtata
     9121 ccataccagg aacggaagtt gtttaccttc tccctgaagg aacttagaaa taaggttttc
     9181 gatttgcacc aaatggccgc tactaatgcc cgcgccccac cgtctaccaa actacggccc
     9241 tttgtatacc gaataacagt taggtgacgc ttggttcatg atgagccagg aggacgccca
     9301 caactcttgc aagattcagg gttggtcgag caatccagaa gactcagatc acgaccaatg
     9361 tggcgaaagc gacaccgaaa agacgtggtt ccctggcgat gggatctgtc caccaacttc
     9421 agagttcctg gcctgctgtc gagccagcta tcagctttgg gcccatgcag catcgtcccc
     9481 acggccagac gatggacttc tcattacccg tattacccgg gcctttgtga ggatgctcga
     9541 aaatgttccc cgttttctct atcatccgcc caaaaacgtt gaagttctcg gaacgtcagg
     9601 cacacgtttg actgtgcagc catccctccg catgcgaacc acagaagata tggattgtac
     9661 gcagcactat aagtggttgg atgttgttca atgcctcggg gttccagtac ctaagtctta
     9721 cgaaatgacc accatgcaac agcaagagat ctctctcacc tcagcacccc tgaaacgtgg
     9781 tcatctaact agtattatat tggcttggtc gtacatcctt tcgtgtcgat gggttgagat
     9841 cctacaagag gctggatgga acgcttccat tcagcatgag aaaggtttgc agatcgccga
     9901 cagcttctgg aagttagtta cacaaggtcg ctggcaggct agcgtaaaga ccgcgaaggg
     9961 tacacattat tcaccatgga tgttaataga aagtaacagg aacctgaagc ttcagaagtg
    10021 gtacggtagg cttccgtctt ggatcgtcgg attcggctaa cacgctgtgt atgacactgg
    10081 cagttgggct cgatcgtctg cctcattgtc ggcctttgag atgctcctgg gatcctgcat
    10141 ttcagaaggt cttgaggctg agcttcttac tggactggct tcggttctga tgctcctatc
    10201 acgaaatgaa cggccatggc tgagtccgcc gacttctatc cccaaaaccc ccacgacccc
    10261 agcttccact tgctctgcta ggagtcacgc cctttacaag ctctggggtt gtcttgacaa
    10321 ggccatgtat ctcagttcca cgagagctgc tattgaatca ttgatccgta gcgctttctt
    10381 tgattcgtca gttccttgtg atcttctggg agcctccttt tccggtataa gagaggcgct
    10441 ttcctctgca gatgagtttg accctcagcg agcgttacat gcaatcacca accggaggcc
    10501 acatttgagc ccgttgtggg ctgctgagat atgcatggat ccagacactc tttcgtatga
    10561 agtcctcgat tgtttgccac ctatctgcct gcctgccgcc ctctggacgg gtacaatgca
    10621 gtcattcctc caggtggcat atcggtccga cgaaccagca gatctagaag caaaattact
    10681 tcgtgcccga gagttccaaa tcgcttactt ctgccaacct agtatacccg tcccagagac
    10741 acctgctcct ccattcggtg aaacgatctt gaacaacgtc agccgtgagg ttgaaacaca
    10801 catggcacat gaacatatga ctaggtcgtg gcaaatgtac tggacaacta aatctggggc
    10861 gaagaaaccg gcgaccgcac aatatgtact tgaacttgta gaagctcgaa tggagaagga
    10921 tgttgctgac tacaactttg acgaagagta agtatgataa cttctcggcg ccaatgcact
    10981 tgctgatgtg tttgaagatt cccaatcaag ttaagagagg ccgtggacga aatttcatgt
    11041 tgtgcaacaa gacgaatgtt caattggcat cgagaatacg atggcggcat ttcgcttgat
    11101 gatggaacca tgagtcctga aaccgttcgt tgcttgcaag cacatccatg gatttcgggc
    11161 ccattgattg actctaacaa gtctatccaa gttggtggag agaatgatca ctgggatgac
    11221 aatacccaac gtattacaat tcagaaagag gtgaaaggcg gtgtttcaac cagtgattat
    11281 attttggagt ggcataaaga ggtagagaga tgcctagggt ctgaagacgc cagagtctct
    11341 agttgaactc attagttccc gtgatactcc gccgaaggcc aaagtattca tggatcgatt
    11401 gtttctctat ctcatttgcg gcggaaatgt atttgctagg ctaataattc tcagaatgat
    11461 acagtgatta ctacaagtcc attattgata ccactagcat catgctacag tcagccaacc
    11521 ggtcaaaaaa tagcctctct tcccaactgc atactagtat ctggtagcta ctctaacctc
    11581 caaccagtaa cttgaaataa tataactgtc tctatcccaa gaccaaaatc atctccacga
    11641 agcaccaccg tgaagaagaa tacatctaaa taagttaaca tatagcatac atgactctcc
    11701 cttcatgtac cacagctcat gatggaagca atatacatta gagtcggttt atgcaagtcg
    11761 catggcttga tgttgccgag cgggaagaat tagatccagt catctgcaca cattgaatgc
    11821 tacaagaaat actctgggct ataagcaaag atagactctg cacggtccaa tgcttattcg
    11881 cgtgcaggat aactagtgta tgactttgca ttaatggcca taaatatact gtaacccgag
    11941 tctaggacag gaaagaacat gatgacttga tatactacta tatagtgagt gacctgttct
    12001 gtgggagata ctactcatgt ttatccaccc aaaaaaaaaa gaatatgaga tcaagacaag
    12061 atgaaacgag aattacatgt aactggtcgg tcgttatatt cagtgaacta actgataatg
    12121 gtatcgtatc atgctgctta tatcgctaca aagaaactct tctcgccctc cttcggcacc
    12181 acgcgtgccc gttcaataat cggatcagca cagctgaccc ggatccgctc cggagtcgct
    12241 ggactctcta gccgcaatac ttccttgacg ttccattgct ggcgcgccgc cttgagcgca
    12301 tcgcggatag caaagaagac agcgctgccc atgaacagcg gcggttcgcc aacaccacgg
    12361 gatcgctgga tagtccgcag gttctcccac tccacgtcct tcagtagact gacgttgaag
    12421 atctgaggga tatctcggaa tccagggatc ttgtagtttc cggggccctt ggtgaagatc
    12481 tgtcccgacg cccggtgcca cagactctct tcggtggtga aaagaccctg gccttggatg
    12541 aaagcgcctt cgatctgtcc gtagtcgatc gatgggttga tggtacgacc aacatccatc
    12601 ttgatgtcag cacgcaaagg agtccagtcg cctgtgagcg tgtcaatctg tacttcagcg
    12661 gccgttacac cctgtgtgaa gtagaaaaac atctggccct tgttttcgcc ccacacgtag
    12721 ccaatgtcag gagtacggta gtatccctgc gcggagaggt tgacccggtc aaagtaggct
    12781 gcgtgagcga ggtctttcat agtggctccc ggcattttct cccggtacgg cttaagacgt
    12841 tcattgagct gctcacaagc gttgtagatg gcgtagccat tgagatcaga actggccgac
    12901 gcagccgtgg acgatgtgtt ggccacagta tttgtggcag tctcggagat aaagacgttg
    12961 gattggggca cacctaaagc ttcagcagcg atcatagtca tcttggtatg tagtccttgg
    13021 cccatctcca ctccaccgtg agccacaaga acacttccgt cgtggtaaat atgcaccagt
    13081 gcgccagcct ggttcagaaa tagggctgtg aaagagatac caaacttggt aggaatgaga
    13141 gccattccgc gcttggacca cttgtgcttc ttattatatt cctccacggc cttccgtcgc
    13201 tcctcgtacg agctctcatc cataacctgc ttatacatca acggcacatg ccagtcctta
    13261 agctcctggt tgtagtgggt cttgtctcca ggcttgtaca tgttctgcca gcggagttgt
    13321 tcgaccggta tctgaagatg atccgcaacc tccgatacca tgcactcggc gaagaacatg
    13381 ccctgagggc cgccgaagcc acggaacgcg gtgtttgaaa cggtgttcgt cttgcagata
    13441 cgaccacgga cgtgcatatt cggtatgttg tacactccat caatgtgtga aagcgctctt
    13501 tcaactactg caccagacag atcttgggtg tggccaccgt tggcgtatac atccgcatca
    13561 aatgcaagca gtttaccttc ttttgtcact cccaccttcc agcggcagaa gaatggatgg
    13621 cgctggcccg aagtagcaat atcctcatcg cgattgagca tgcaccgcac aggtagcttc
    13681 gccttcgcag cagcagtagc acaaatacca gccagctgga ctgaacgcgt ctctttgcca
    13741 ccaaagccgc ctccaaggcg ctttacccga gacacaatct tgttggcagc tacaccagtt
    13801 acttgtgcaa cgtaagtttg cctaaaaaga atcagtatag cctttcttgg ggtagatgtc
    13861 atgactcacg tttccgttgg gttttgtgtc ccactccaga tctccatctc tccatcctca
    13921 agcttgggga tagcaacaca agcctgagtt tccaggtaaa agtgttcctg accacccatt
    13981 cttgactgtc cggtaaagac atagtctgct tctttgaagg ccctctctgg gtccccacac
    14041 ttgataaagc gggagtgttc aaagaacgac tcggcctcaa tggcttcttc catactcaag
    14101 attgccggca gctcctcata ttctaccttg accgctcttg caccctcctc cgcaatcttg
    14161 gccgatgttg cgaggatcat accaatgggc tggccagcag ttgtgacttc atcgactgcg
    14221 aagaaaactt catcgcagtt cggagctccc caccaattgg ccttggggtt agggagatcg
    14281 gtatgatcca cataatgagc aacgccagga atatcgagag cggccgaagt atccacgcta
    14341 agtatccgag catgcgcctt ggtcgaaaga accatgcagc cataaagctc gtttttcatc
    14401 atcggcatgt cgtcggtgta ctgtgcttct ccagtagctt gcttcagtgc agaaacatga
    14461 ggactagcct ttccgagaat cttctgttga tatgctgcag aagcctcgtg atctttctct
    14521 ccagaggaaa tggccctttc aatctcggca atgacatctt catcgacatc tgcgtccgtg
    14581 acctggatgg aggacagtac atcgtggtag aaccggtaga agaatcccaa ggcgagagac
    14641 tttctgtaag tcgccattcc tccagggaca ccaaacttca agtcaaagtc ctgctctaag
    14701 gcacccatgg taccctcaag ggtagcaggg ttggtgaact tcttgccagc caaataggcc
    14761 tctgcattgc gtgcggacac ggtcattgga gctagccctc caaagaccaa gtttacgctc
    14821 tgcacatcgt gggaaggaga aagtgagacc cgcaaagctg cgttcacgat cgcgatgtca
    14881 tcatccttcc tctttgactg cttgtaggca cgcagatatt cccccttctc ggacgcaact
    14941 gggatccgta aacaagcgat aatagcgtca ggcgggagcg cagtggatcg gtagcccttg
    15001 aagaactggc tcatagggat ttcgataact tcacccaacg acatggctac aaggacagtg
    15061 ttggtagcca caaagactgg atttaggtca gagattggag atgctgtagc cagatttcct
    15121 gctggtgacg cgacgttgcg aatttgtctt ccagcaaaat agcggagttg cttcttgatg
    15181 gcgttaaatg gctggcctcg caaaggccca tagcgttcga gggcctcatc acagattgat
    15241 tcgagatcgg tcaaggagac attggcccca atctccaaat ggtcatcctt gagcgaatac
    15301 tgacggagtt ccggaatatc accgacgtag acagaggtgc tgtacctcat agccttgaat
    15361 ttgacctcaa tctgtgtctc tgtgctccct ccaatgatct tagcatcagg atgtacagct
    15421 ttgatctcca ataattgttc gagagtgacc gggcgatacc acttcttttt cttgttacca
    15481 aggaccaaag ggcggaattc gtgcttgtgg agctgaggcg ggaaaatcag ctccgtgccc
    15541 ggagtgtact ctatgaactc tggcggcgtg aatttcggac catctccatc tgttgtgtct
    15601 gccgatgacc gcttgcagca acccccagcg ccgttctgtt tatccatgca acaacctgtg
    15661 cctccgttcg ccagggattt cccgcagccc ttgggagctg tgaagctctg ggcagcatcc
    15721 aatatgggcc tgtacccggt gcaacgacaa agattcccgt caaatgcttc ttcaacgtcg
    15781 tgttcagtcg gcgcagagtt attgcgtagg agggcataga ggctctgtag atctgtcagc
    15841 ttagtcccgc cattcaccat acttcgaaga gcataccatg acaattcctg gcgtacagaa
    15901 accgcactgg cttccattac caaccgcaag tcgctgttgg acagcatggg gattcttcac
    15961 atcgccgata ccttccaccg ttataacatg tttcccgtct acactgatta agggtgcgag
    16021 gcaagcgttg actgaagcat gataaagctt ctttgtcgtc gtattgaaat gcgatacaac
    16081 ctggttcacg tcaacatgaa tccaaatgct gatgaaatga cctggataca taccactgtg
    16141 caagcaccac agccaccttc cgcacagccc agcttcgtac ctgtcagacc gataccccgc
    16201 agatactcca atagcgtgac ttccggattg atcgagtcga ggactacttt tgtgccgttg
    16261 agatagaagc gaatagtgtc atcccagtcc tccgtgagct gagccaaggt gacagcctta
    16321 ctggcagcca ccgttggctt tggtgattct aaaatgcctg gggccatctt gtttcctgga
    16381 actcaaatgc ggaaaagtcg atttccccgc cgagatgagc ggacgccaag accggccggt
    16441 gtaagaaata atcaagttgg ttcagagttg tattaggata ggatccatga aggtattcag
    16501 agccgaagta tttcagaaca tagaaggata tacaataaaa cttatggtgg caagatgatg
    16561 aagaaagggg ggaagtccct ccccggcatg agctaaccaa ggaaatgtaa agtcatgcac
    16621 aagcttatcg ttgcctcccc actgcggtta tcgctggcta tcgctggccc gcccggcggc
    16681 gatcgccact gtccgatggg cggtaactta cggcagatgt catctgatca ctaatctagc
    16741 gactctcact ggtgcccggt gagcaaccta gtagtactag taagtactct aaagagaagt
    16801 tagtagtctc aatagttgga ctcttggtaa gtaaatgagg aaacagcaag gcatgaaatt
    16861 atatagtaag agatcacggg cctagtacca acagcaagaa agaataatga gtatcgatca
    16921 acgccgttcc caatgctttg gccgaagcca cccgggccaa gataaatagt aaacagttca
    16981 agcgaagaga agcaatgtac accaacaagt actagcaata acatgtctat gagtataaga
    17041 gaaaaagaaa gacactaatt atacttttgg cttggctcca atgaagtcct tttcttcttc
    17101 ttcccatttc ttgcgttcca cgacgctgcg cgcactgtga acgataactt gttagctcat
    17161 gtcattcaat ctttgattct ttcctttcgg ttccgtaata aggagaaaga cgggaacgct
    17221 aggaaaaaat ttgtagtcct gtgtcggtgt acataccggt atgctctcac gaatcgccag
    17281 acttccgtgt ccgccaagtt ccaagcctcc gccacatcgg tgatacaaat tcggttggta
    17341 cctttgccct tcagaaattc ccgtgcctgt ttcaggatac catactcctt ctcgacaccc
    17401 tgctcactcg ggttggcctg ttggatggat tccttcttct cttcttcatt ctttgcatca
    17461 accttgccat cacgcgggat cttgaatcca aactgccact caaactcgtc taagagctcg
    17521 gaaggcaggg actgtccggc ctgagggggt agcgactcaa cagtcatcca cagggaggtg
    17581 cctacgacgg cgtcatcggc aacagctctc ttaaaaacaa cagctctcgc agaaccaccg
    17641 atatccgtgc caaggtgctc tttggtcact tcagccaacc atacatcacg gtctgtctcg
    17701 cggcgaatgt gccgcgttgt aacctcggta gaatcctgct gcagactgat gagcgtaaaa
    17761 ggatgaggca gagtcccgat cgtgaagacc tgggtcgtat tcctgtaagt cgctggctgg
    17821 ctaacctgca tgggcttttc agcatcgcag gggtgacatt tcggcaagtt cggagggcac
    17881 gagcggggaa cgggagaacc aggacattga accagggctt tggcaagccg tagggccggt
    17941 tccaccagag ccgtagtatg ctcagggaat ggtttcaata cagcaatgcc tgcagggaag
    18001 gagttctgga aagtgttgtg caggtgggca ttgatcaatt cagccaaggc cagtcgtcca
    18061 gcggtaggcg aagagacaat tttctcggca actgtagggt agtgactggt aatggcagtc
    18121 gagtcgtaaa gagccagagc gttaggctct tccaccttga agaattcggc tggaagcaaa
    18181 tctatcaaag aggtggactt gtcatccacc ttgttcatag cctccttgat tgcatcattg
    18241 atacgtgatt tctcgccagc aaatagagca ttcccaaagc catcgaagcg ggtgataagg
    18301 gcaggatcgg tgcctcgacg cagataagtg agaagagcgt tatcgtaccg ggccatggga
    18361 aagcagtgcc aatccgcaag cataccatca cccatatggc cccaagctag ccacctgaac
    18421 agctcacttt caagctccgg cttaagattc aagggctgaa caagctcgta aagctggttg
    18481 ttcatggctt caccagggcc aagaatgacg gggcggaatc cttgcgcaaa ccaagccctg
    18541 cgccaggcga gaagcagctg cgcgtccgca ttatcctcct cccgatcgtt tcctttattg
    18601 ggttcgtagt acgtgtagat gaacgggcga tttctgagag gggggaggac ggaacggttc
    18661 tcatcgaggg tgatcgatga cgagaaaggg ttgatccacg accaatcgct gaaccacttg
    18721 gactcgccgc tggtgctgtt aggttgcggt tccggaggtg tatgcactgt cgggtgaaac
    18781 gatggcagat gcaggttatt taacgaagga agtttcgggt gagggacata tttggccggg
    18841 ccggagactt cctcaccagt cgaagggtcg gtcgtcgggg aggaagagaa gatgaccaag
    18901 acgagggcaa caaagacgat gatggtaatg agagccgtgc tccgatgagg gatcattttg
    18961 acctaggatg cacggcctgg atcaggcctg aatcaatcag gggaaagctg ccgagtggaa
    19021 gttccgtccg tccaagtcga aagtgagaaa gtgactggat gttcttctgt gaggctcctg
    19081 cctgtcccga tgcgggtggg aaacgaacgg taagtaataa actaggtatt acggtcaaag
    19141 tccttagggg ggttagggga tggaactgaa ggagcgaagg ttgttgaacg agggagtaat
    19201 atgacaacgg gaagaaaagc gaggtgtgaa agagacgtca gagacacgtc tattaaccca
    19261 tggcaagcga gagtacgaag tgacaatcca aagcacctca gcaggattgg aagcatagac
    19321 tgtgaggcag cgttgcactt tgttcctgaa caacccaatg cggaagtgcc tggaaggggt
    19381 tcagaagcct agacccaagc gggtaagtca gcgatacgac ggtgtctcca tccaagtggg
    19441 taaagagtcc cagttgtttg tacaggatgt gtggtaagcc accgccgcat gtggcggtgc
    19501 aaatgggaaa agcggtcagt gtattattac agccggagag attccgggat tctgctggtt
    19561 gtaccccaga ggcggtgaga tcaccgccat cgaaatgatc ctcccaaatt gtggggagga
    19621 gaaaggaaac ctcaggctag tactgtctgg tgggctgcag ccgacatcgg cactttttct
    19681 cgcgtgcccc tcttgactca tcgctgatcg ctgctcttcc catctttaat tccaactaat
    19741 tcattaattc cctactgacc tttcatattc cgccaagtgc agttgacgtc cctcatctcc
    19801 ccccacttac aagggcatcg caactgtaac aatggctgtc gaatcagtct ccttgcagga
    19861 gcgcctcgag cgatgggctc agagactcca gaacctcaca gtgtctcccc tcacccgaga
    19921 ctatcccgac aaccagaagc aggagcttcc caagagggca attgaagcct tcgagtccat
    19981 tcagctgtcc aaggagacgc aatcggactt gcagaagatc tcgggctctt cgtccggatt
    20041 tactgtcttc ctgacagcgt tcatcgtgct cgttgcacgg ctcaccggtg acgaggatat
    20101 tgccgtcgga accagctcca gcgacgatgg tcgtcctttc gtcctgagag tcccaattga
    20161 ggcatctgaa accttcctac agctgtatgc caaggtccag aaggtatgac tagaaaaaaa
    20221 aaataattca aggtagcgta tattatcata gtcgctcatc taacctttgt tcaggcattc
    20281 gagcaaggct cggccgagat cgtacctctg ggcagtctac gatcctatat tcaagaaaag
    20341 tctcagtctg aacgctcccc cgtcctcttc cgctttgctg cctacgatgc ccctgctgcc
    20401 tctcaggatt accctgccaa caccttcgag acaacagatc tggttgtcaa cattgccccc
    20461 atcagtgcat cggatggctc cacaacccag gcggaactgg gagcttacta caaccaaaga
    20521 ctcttctcta gctcgagaat ttccaccatc ctcaagcagc ttgcccgttt ggttgaaaat
    20581 gcgaccagca acccggaaca agcaattggc cgcattgact tcatgactga agatcaactg
    20641 gcccttcttc cggacccgac ctccgatctg aactggtcca atttccgcgg tgctatccac
    20701 gatatcttcg ccgctaacgc tgagaagcac cccgagagac tctgtgtagt ggagaccaag
    20761 tctgagcggt ctcctcaccg ggagttcacg tacaagcaaa tcaatgaggc ttcgaatatc
    20821 ttgggtcatc atctggtcca gtcgggcgtg gagagaggag aggtcgtcat ggtgtacgct
    20881 taccgtggtg tcgatctggt ggtggccgtt atgggtatcc tgaaggctgg cgcgaccttc
    20941 tccgtcattg atccagccta ccccccggaa agacagtgca tctatcttga tgtggctcgc
    21001 cctcgggcac tgatcaacat tgagaaggcc acaaaggatg ccggcgagct ctccgatgtg
    21061 gtccgctcat tcattaacga gaacctggag ctgcgcacgg aagtccctgc cctggccctt
    21121 cgcgacgacg gctccctcgt cggaggatca atcaacggcc aggatgtctt ggccaaccaa
    21181 gttcctctga aagccaagtc tgttggcgtc gttgtcggtc ccgactccac cccgactttg
    21241 tccttcactt ctggctcgga gggcaggccc aagggtgtca agggtcgtca cttctctctc
    21301 gcatactact tcccatggat gtccgagact ttcaagctta cgcccaacga tcggtttact
    21361 atgctcagcg gtatcgctca cgacccgatc caaagagata ttttcacccc tcttttcctg
    21421 ggagctcagc tgctggttcc tgcccgggag gatattcaga acgaaaagct tgccgagtgg
    21481 atgcgcgagt atggagctac tgtcactcac cttacccctg ccatgggtca gattctcgtc
    21541 ggcggtgctt cggcacagtt cccctcgctt caccatgcct tcttcgtcgg tgatattctg
    21601 attaagagag actgccgctc tctgcagggc ttggctccca atgtcaacat cgttaacatg
    21661 tacggaacga ctgagacaca gcgtgcggtc agttacttcg aaatcccgag ctactcgagc
    21721 gacgagggct acctggatac tatgaaggac gtcattccgg caggtcgggg aatgcttgac
    21781 gttcaaatgc tggttgtcaa ccgcttcgag cccagccgca tttgcgccat cggtgaagtt
    21841 ggcgaaatct acgtccgtgc cggtggtctt gccgaaggct acctgggttc gcctgaattg
    21901 aaccaaaaga agttcctcaa caactggttt gttgataacc agacctgggt tcagaaagac
    21961 caggccaagg cagacagcgc gaacgagccc tggaggcagt tctaccaagg tcctagagat
    22021 cgcttgtacc gcagtggtga ccttggccgg tacactcctt cgggagatgt cgagtgttcc
    22081 ggacgtgcag atgatcaggt caagatccgt gggttccgta tcgagctcgg tgagatcgat
    22141 acccacctgt ctcgccatcc cctggtgaga gagaacgtca ccctggtgcg tcgtgacaag
    22201 tttgaggagc ggactctggt cagttatttc gtgccggaca tgagcaagtg ggctgcttgg
    22261 ctgcaagaga agggtcttga ggatgatgac tctgctgaag gaatggtcgg catgcttaga
    22321 cggttccgtc ctcttcgtga cgacattcgt gacttgctgc ggaccaagct cgcctcctac
    22381 gccgtgccga cggtgttcat ccccctcaag cgcatgcctc tcaaccctaa cggcaagatc
    22441 gacaagcctg cgttgccctt ccccgatacc gcagagctta gtgccgcagc tcctcgtcgc
    22501 aagtcatctg tggtccaggc tctatctgaa accgagcagg cgctggcttc aatctgggcc
    22561 tcacgcatcc ccaaccttac tgctcgcatg atcggtcctg atgactcctt cttcgacctt
    22621 ggagggcaca gtatccttgc ccagcagatg ttcttcgaca ttcgccgcaa gtggcgcgga
    22681 attgacgtta gcatgaacgc catcttccgt agcccaaccc tcaggggatt cgccgccgag
    22741 attgaccgtc tgcagaactt cgagtctttc gccagcaatg atgacaagac cgctgctaag
    22801 gcagatgcct cggctactcc tgacgagctt gatgatgagt attcgaagga tgcccggaag
    22861 ctggcagaga cttccttgcc cgcctctttc cccacgcgta ccgagcctct cctgtccagt
    22921 gagccaacca tcttcctgac tggtgccact ggcttcttgg gtgcgcacat ccttcgtgac
    22981 cttctcactc gcaagtcacc catggccaag gttgtgaccc tggttcgtgg taagaccgat
    23041 gagcaggcgc ttgaacgtat ccgctccacc tgccgcgcct acggcttctg ggatgaagcc
    23101 tggaccagca gactgcagtg tgtttgcggt aacctgggtg agccacgctt cgggttctcg
    23161 gatgctctct gggacgactt gaccaagcgt gtggatgccg ttattcacaa cggcgctctt
    23221 gtccactggg tctaccctta ctctaccctt aagccagcca atgtccaggg caccatcgat
    23281 gcgctgaagc tttgcgctag tggaaagccc aagcagttct ctttcgtcag ttccaccagt
    23341 gttctcgaca gcgaccacta tgtctctgaa tccgagcgca tcgttgcagc cggtggagcg
    23401 ggtatcagcg aggaggacga tctcgagggc agtgccgtcg ggcttggaac cggatacggc
    23461 cagagcaagt gggctggaga gtacctggtc cgtgaggcag gtcgcagggg tctgaaggga
    23521 accgtcgttc gtcctggtta cgttcttggt gactccaaga ccggaagtaa gcgaacctcc
    23581 aacatattga ctcccagatc atgctaacgt gtaaactcta gctaccaaca ccgatgactt
    23641 cctcatccgt atgatcaagg gatgcatcca gctgtcttcc cgccccaaca ttaacaacac
    23701 cgtcaacatg gttcctgtgg accacgttgc ccgtgtggtc atcgctgccg cattccagcc
    23761 tccctgcact cccatcggcg tcgcccaggt cactggacac ccgcgtctcc gcttcaacca
    23821 gttcttgggt gctctccaac tgtacggata cgacgtcccg caggttgact acgtcccctg
    23881 gtccaagtcc ctggaacagt acgtcaatga cggacagcac gacgaccccg agtctcagca
    23941 cgcactgtaa gctttaaccc taacccaata atcccacgtt ataccccatc acgatactaa
    24001 catcccgtcc cagtatgccc ctctaccact tcgttacctc cgacctcccc tccaatacca
    24061 aggcccccga actggacgat gtcaacgccg ccgcctctct ccgtgccgac gccgcctggt
    24121 ccggcatcga cgcctccgcc ggcgccggtg tcaccgagga gctggtcggt ctgtacgcct
    24181 cttacctcgt tcaaactgga ttccttcctc ccccgtctgc cgcttcggcc gcagctcggc
    24241 ctctgcctac gactcagctg agcgaggacc agaagaaggc cttgtcgaac gttggtggtc
    24301 gtggtggttc ctcttaagtt tatacatata agtttgtcac tgtctagcgt gctttgctac
    24361 atgggttttc gctttggggt tatgtgggtt gcttaatttg tgtggcacat tgtatgaggt
    24421 tatgaccttt tttttccttt cttgggtgac ataaaagttc ttgtatggct tgatggggag
    24481 gctgaaaaaa aatgtataga aaggactgta tatgaggtgg gtgggttggt ttagaggtaa
    24541 aggatttccc tatttcatca atgggctatg gacgagttta gatgtttcta tgaatacata
    24601 gtcaagtatc ttatttcatc gatacattat ttcgttactg aaaattatga gcctttctgt
    24661 ccaaacagca aaatgtcaaa gatcccttgg tgtcattcta gaccttcgaa tccaggaaga
    24721 tcaggaaggg ggccacgcag cgggcgtagt gtctaatgaa gtgctttgct acggtaaagg
    24781 tttcctcggt tttacggtgc aacatagttc gatgcggatc aatcttattc ttcctagcaa
    24841 gcaagactaa acaaaactga taagtaagga tcgactgaaa agcaacaaat aacaagacaa
    24901 agcccgagac ataatcatcg tcaccatctc caccgtgatc cgcatcaccc cgtcatctcc
    24961 aaattgattg tcatagatga gtgttgtcat cagggacccc aaagggcttc ttccagcggc
    25021 catcgactca gccactagct agtaccccag gtagcgtcac cagtgtcagt gccctggaag
    25081 gtgaaggatg aggcgttctg gacgatacgc gcgactggct tgtccgactg gtcggtggtg
    25141 aagaagtcga tgatgaattt ctggattgcg ggttagcagc atgccttact attgtcctga
    25201 aaaatggaaa tgggagtgca tacgcttcca tccatgtaga tttggacgct ctggttgccc
    25261 tggagatatt gttggtcgtc atagtagacg gttgcactgc tggctattag aatgtgatga
    25321 tttgtatgaa taaagggcaa gacttacttg ataaaagcac tgttgggcct gtagaatcca
    25381 gcagcttcac ccttcacggc ctgtcccatg ctctttgaag tcaggtcaaa agtcaagtca
    25441 acccgagaga tgttgacttt gccgctgatc cggtcatggt agttccagtg atagcaagag
    25501 cagccattcg catgcgccaa ggatgcctcc agcatctgtc gacccagggg ccggctgatc
    25561 tcctgctgga aggccttctt gatttgtatc tcagacacat cgtggccatc agaactggtg
    25621 atggtcactc ggcgaaaaag ctgcaagagc tcctcgtccg aagagcccga gtgcgaaact
    25681 gcctggagag acatggtctg cacaggagga gcagtggtca caacggtaga cattgcgaaa
    25741 atttgatttc ttgaattaaa aagagtagag tcagaggtta ttcttggtac tgttgcttgc
    25801 tttgcgagct ctgttggtga tgatgctggg aagaaggaat ggaggagatt ctgccttcct
    25861 tatataggtt ttgagactga gtgaagacta agatttgaca ttcagctccg acttctgttc
    25921 agatgctttg agcgatgcga gttcgtgact ggtagagtca cttcgagtaa acacctcgag
    25981 gcatgcctgt ctcggacctg gatgtcgagt ggaaacttcg ctacgaactt ccatctgcac
    26041 gatggatcac atttcagctg tccttgagca ctcggatctc acgatagcaa gtctgatgtc
    26101 ttcgttgggc atgaattcgg ctatgcgctg cgaagctgct tgcgatgggt gtctccatct
    26161 tcgaaagcat gactttggag tatacagtcc agctagccac attctcatct ccaaggtgag
    26221 aagttgtagg catgggcatg aagctattgg ctctcagccc atacaggagc aggcattact
    26281 cttcccataa atcccgtttc tcatcggcta ttttggctac tggtcatcat tggtggttca
    26341 tatgcggcta gatgtctgta catagtcaga cctacagaga acgataattt cttacatgaa
    26401 gcaaagctgc tagccatata gacgcacccg tttgttttga cgaaggatca caacgccgtg
    26461 ctggaatctg atggacagac ggtctagtct gtacctggct tggatataga ctgtccagtg
    26521 agattctctc aacggtgtct gtcgaaggac atgaaaataa cgcatctcca atcagaatta
    26581 tcgaagacat aatcaggtat acatatccat ggcagtttgc gcatcttagt agccacatac
    26641 atgcaaaaga atttctcagt aagaggaacg atgctcaccc gacgagtcag cggtgaacgg
    26701 cggtcttctc ctcatagctt tctagatgta tatgaatact acctagatgt ctgtcgattc
    26761 aagaccgttt attgtcccta aacgtcaggc tgcactgggt aagaatgtca tcgagtcctc
    26821 tcagaactgc caaatccacc gattggtgat attgggaact gatctgggtg ctggaaaaag
    26881 ttcatgcagc cagtattctg caggaagccg cgtgaaccac tgacgagcag tgacatgagt
    26941 agagtcaacg ttcgacaggc tgcgatcaga tccagctcgg gaatttttac cagatttcct
    27001 tcggacctgc cgggatgtcc ggactgttca gccatgacat acggagcttg gcttcagagc
    27061 gcatagcccc acgacgtaac agttcagcca gcccttgatg ctacagacgt ctgtccggtt
    27121 tttcgtacgg aagaggcagc ttagccaggt ctgtggccaa gtcggatact ctgcaatacc
    27181 tgcaccacgt gcagaatagc tcattgactg ttgcgcaaag ctgagggtgc cccagctatt
    27241 gtcgctatgc agccttcagt cgcctgatgg ttacatcgga ccagtctttc cccagaaaac
    27301 cagtgaatca tgaagcagtg gctggcgcca ccgccaccag caccgttcat tggcggggtc
    27361 gccttgctcg aacgggatcc taccccggcg tcttattcct ctgtttccga gcgaagaacc
    27421 accgtgattt tgttgtggct tccgcagggg ttggagtgtg cccaggtata actctagcag
    27481 gttatcctat caggagatcg ctgcctactt acttagacga gacggcgatg atgatttcca
    27541 caaggcacgt gcagcagcag tacattcatt ctatcagaag agagtagagg tagtggtgtg
    27601 actgaggcga aaagcaaaga agatcgaacc gaataggatt atctagagag agagagacag
    27661 agagaagaag aagaagaaga agaagaagaa gaagaagaag aagaagaagc agcagcagca
    27721 aacaagcaaa gctgcggatc acgggattcc ctccttggcg gcccctcctt tcttttttct
    27781 tgtctattag tattaaaatg ccagtcctct ccatcggtcc ccagtgtgct gtatatttgc
    27841 atcgtgaaag cccctctatt gtcttccata gacacacatt gtgccgtagg aatggatgat
    27901 cttcatgatg aaccccgcat aagcttcccg accctcttga ccgatgggtc aagcgcagct
    27961 caacccgaga aaggctgtcg gtaactcatc ggctctggca actcatcgct tcgcactttc
    28021 ggcaattcgg tggggagctt aataatgggg tcaaccagct ggctcatggc tcatttatgc
    28081 ttcggcaact caattgagtc tgactagcta gccccgctcc tttattttgg acttcagtca
    28141 gtggttgcta ggaagtattg ataagctgct tgcagtccca tcaaggtact ggattttctc
    28201 gtaaactctt ctacattact tccctccagc aattggtcac ttagagcctt atttgtacgt
    28261 gaatttcaca tctcataacc tccccgcatc tttccgcgtg cttgtggaag tgactaacat
    28321 ggcgttacag tcattcaaac tgatccatca tggccaccaa caacgacatg gaatacgtcc
    28381 ggtatgtaaa ttgtgattgt gactcatctc atggactctg acttagctaa cggaattggc
    28441 atgttagcct gggaaactcg ggactgaaga tctccaaaat cattttgggc gccatgtcct
    28501 atggcgccaa acagtggcaa gattgggttc tagacgagga agaagctctc cctttgattg
    28561 agcatgctta caagcgcgga atcaacacat gggatacggt acattcaaac tactatctcc
    28621 cttttgcctc aatacgttac taactagctt ccaggctgat gtctactccc acggccgttc
    28681 cgaggaggtc attggcaaag ccctgaagaa gttctctatt ccccgtaacc gggttgtcat
    28741 cctgaccaag tgctacttcg gtgtggatga ccaaggcaac ttccctccga tttctgcttc
    28801 cggtgctaac gacggtggtt tcgtcaaccg ggtcggcctg tcccgcaagc acatcttcga
    28861 cgccgttgac gccagtgtcg agagactggg aacctacatc gacgtgctgc agattcaccg
    28921 gctggatcgc gatacccccc gtgaggaaat catgcgggct ctcaacgacg tggttgaaag
    28981 cggcaaggtc cgatacattg gagctagcac ggtacgtctt tcctgttccc cctttcctcc
    29041 agcgacgcat gcttacgcct atcaagatgg ctgcgtggga attccagacc ctccagaaca
    29101 tcgccgcccg caatggctgg caccagttca tctccatgca aaactaccac aacctaatcg
    29161 ccagagaaga agagcgcgag atgatcccgt actgccgtga caccggcgtg ggcctgatcc
    29221 cctggtcgcc catggctcgt ggtgtgctga cccgcccgtg gggctctcgt tctactgtgc
    29281 gtgaggcgac agacggggca ctcaagttcc tcatccgcag ccgcgagacg gagtcggaca
    29341 aggctatcgt cgaccgtgtc gaagagatcg ctaagaagag gggtatcagc atggctcagg
    29401 tggccatcgc ttggtcgctg agccatccca atgagaaccc gattcttgga ctcaacagca
    29461 aggagcgcat tgacgaggct gttgccgcta ccaaggtcaa gttgactgat gaggagatta
    29521 agtacctgga ggagccttac atccctaagg ctatcactgc tctggagcgg taaaggttag
    29581 aatatgatca tctaatcaat gtcactatat acacagtaaa atcaatctgt tcagtcacac
    29641 aaatgagcta ccattcattg aatttaagta caatgacata aaggacgaac gaactcgtag
    29701 tcttcatgcg catgaatgga catatttgcg attgactgga tctatgaatt caggcttgtt
    29761 ccccctcatt taagccgatc ggttacaaca aaccccgcaa accaattgta gtaagtatgc
    29821 gatccctcgg aaactaaacc cactacgttt ctggctggaa aatgccttct tatcctattc
    29881 cctgcatgta ctatgagttc aaacaataat gtgtcgtatg tgccatttat atgtattttt
    29941 caagctattt gtacgtactc tacaaaatac caggtatatc tccccaaaac aatcaatgct
    30001 gcggagcttg cttagtacat atacacggac aggaaggtgg tgttaatgtt gatggtgagg
    30061 acgggaaaga ggaatcagga gggtaagaaa ataagagggt aagagaaaag gagcgctata
    30121 tcagatatat gtcgtggtat tcatatcgct gggaagtgca aaagagctga gagataatat
    30181 gggagagaca agtgtcatgc aaagttgaaa agtgggagag gccagacacc cagtgcgata
    30241 agaagtagcg atagcttccg gccttacgac ggagaccttg ccatccactt gcatacaata
    30301 atacaaccgc agctccaggc tttcgtgtca ctattgtagt gtctgggaca gatattctcg
    30361 cctctgcaag agggagagat acgaaaagaa gacaactgtc cagagcagat gaaaacaatg
    30421 aatggagata tttgtgaaat gggtatgtgg ttttaaagct ccaggcttgg ctcaatgatg
    30481 atgtccggtc ttgcgaataa tatattcgaa gaggctgcta atccgatgcc gacgctttcc
    30541 cttgctcggc gccgagtctg cgggggagtc aatacctttg tcgcgaaaag aatcggcttg
    30601 gcgtgactgg ttgttttcgt atcccctgga cccgtctatc gcttgatccg gggaagctgt
    30661 catcttgaaa tcttggacgt cggatttcct atgggaaaat aacctgcggc tcttggagtc
    30721 ttgtcgggca ggcttggctt cgacggtttc gtcctgtctc tgctcgcgag gactggagag
    30781 cgtactgtgt cgggtgagac gaccgttgct acccgaagca cgtcggttag tccgctcaat
    30841 gaaggccgca ccagttgagt tggaccgtct cgataagctc ccaaaggtcg tcgatcggtc
    30901 ggacaccgtg gattgtgaag ggacatagct ggatgtcgag aggcgatgtc ttcgaccatt
    30961 tagcggggga acatcatcgt ggccatcatc cctctcggtg aatctgtcag tctcacttct
    31021 aatcgcagtt ggcgagctgt gtctcgacgg acacattgtc ttagtgttga tcgccaaggc
    31081 tgaatcgtcg taagtgaagt tatgagacca gccttcccta aaggctaccc atatgctggt
    31141 gataatgatc agcatgcgaa ggtcattgtc ggttttcaga acctttcggt ccagtggatc
    31201 atccatctcg gagaagtcgc tgagcacgga catggcggaa gttggcgagc cagcaatacc
    31261 cggtgtggtc ggaatcgagt actcatcata cacctcgagg tgattgcgtg tcatcgtacc
    31321 aacaaccggg tgacggcgag tgctaggatt gatcacgctg aacgtaaacc gcttgctgtc
    31381 ctcttgcgag aagcctgggg gcgcagacac gcgacgattc ctcccacctc tcagaaccca
    31441 ccgcaggacc tggataccat catctgtatt ggccacaaac tcataggagc cattggcaag
    31501 aggcgtggcc tcccaaactg gtccatggtt caaacagatc tccgccttcc ctttcgatag
    31561 agcatcgtcc ctgaagagct ggcatatcgt tgcgaccacc tcacgttgtt ctccgccttc
    31621 atcatcggag cttagggacc tatccccatt atcgcccggt gcccgctcat agaggtcact
    31681 agttacgaca atgaggtcat tggggcctag tcctttttta ccgcggaaga tcatcgggaa
    31741 cttgcgagct agaggtggca ggaacacggt ggagggaagc acatccaaaa gtgggagagg
    31801 tcgtggggtt tgcgacacac gttgaagctg caggagaagc ttaggccgga gctttaatcg
    31861 cctatggcgt gcgtgggccg cgggatgcgc tagctggtat gacgttttag ggcgcgacga
    31921 ttgtttccga actgattgcg aacgggcgat ccttgatgga gctaggactg gggtgactgt
    31981 cgaacgctcg tcatcgctcg aggataatgt atcaatggca gctttgcgcg gcattgtacg
    32041 ctgcgtcgtt tctggttccg tgggtttgcg ccggttatag atgctgccta gtccccacga
    32101 tggcagggaa gcgaatgaaa ttgccgggga cgaatgacgc gtcgggctag ggatctgggt
    32161 ttcggatggt aacccggggt attcgttttc gtgagctgct gccgcatccg ctgttaagcc
    32221 aaggttgaat agcattatct cttgggatgc gacaacgtct gttaattctc cccgatcaac
    32281 atggacggca tagatcggtg gcagtgacgg ggattatcaa tgatgacagt gacgggggtg
    32341 gctgtggctg acagaatacg tcagcctaag ccgatgcagc tagttaacaa gttgccgtag
    32401 ttcactggtt tggtacctcg ttataccaga gatatgctga ataattcaga gcaatggaag
    32461 gcaaaagaac aaagataagg aaaagacccg gatcaggaag agatggcggt agtagtagtg
    32521 gtggtagtaa gagaggatat gacgagacaa ggaaggggga ggatggatgg aggatatagt
    32581 aagtagatag aatgagcgtg acctgcacgg gaactatcaa cccctccacc agaataaggc
    32641 tgaagctgca gatgaaatat agcgaaggag gggattgagg tcagcgcagg aggcaaaccg
    32701 gatagatgga tgaatgggga aattcagatg ttgtacgacg tggacattgg aggagcaaag
    32761 agcaaagagt gggcggaagt atgcaaggga ggccggacag tgtgggttag ggggtccaga
    32821 agcgccttaa tattcagact ttcagatgtg cgaggagaaa gaaagagaat acgaatcgca
    32881 tgtcagatgg gatcgatgga tcatcgatta gaggggcgaa aagatggcgg tcaagatccc
    32941 accatgaatc tggtgggcaa atagtcataa ataagaatca tccatcatgc ttcttgaatc
    33001 gaactaaata aatgggggga gggtcaaagt gggaaaaaga aaagaaaaga aaagaaaaaa
    33061 agggtatgaa aaaaaaagga aaagcaaaaa ttacagcaaa aggaacccac atggatccag
    33121 aagtgacaat gacggtttag taggtcacat ctggtcaaga tcccgctggg gggctgttct
    33181 ttccccttag tgtctctgcc agtctgatct gggtatactc ctccgcagcg atgtccatcg
    33241 gaatctacgg tcaagagcga gtcagccaag ccaaatcgtg agaatgaaag tgaaaattaa
    33301 tgtttctagg aacaggctgg gtcgtctggt ctcgttgcat gaactgggtc ctgaccatcc
    33361 atggccggca gctcgcatcc atggccccaa gcagctagcc gacgatcctc ttctttcgga
    33421 actaaccaaa cgccgacact aagatttctt cattggatgg caacctccat cggcggatta
    33481 ttggctgcat cgtaatcctc tcgtattgct tggctcgtat caaatcagcg aggatgatta
    33541 ctacagcaca gtaagtacat agttagtatg aactgtgccc tgcagaatta atcaattcat
    33601 taatcaatta attgttccta ttattatgac gaagatcatc cgaatgcttc catggagcag
    33661 aactatctag gattacagtt aagaaacgga agatgagtag cttgaccgac ccgttgaccg
    33721 acaacagcat ttttcggagc atcggagctg gattatgcaa tggcgattag gtaatggaga
    33781 gagggaagac catgccgctg ctactatatg catacatact actccgtact ttctgcttaa
    33841 gcgtggttaa ttatccccct gtggtgtaat aagcattatc aaccctcata cttgccttac
    33901 ctccatagga actcacaacg cacctctcac gttgcttact ttacttacct cagactacat
    33961 ccctatcagg taccaacaaa gaaaagtatc ccagctcagt cgggctctgg tatcttaagt
    34021 tttttctgcc gcggtatgat gatgattagt ttcggggaga gcaacacccc ctccatcgcg
    34081 gtgtccccgc ggacttcggg ttttcgacaa cttgctgcaa cggaaccgga agctccgaca
    34141 tgccggtaag gtccgcaccg tgccatggga ccggatgtcg gattttagag gcagcaagca
    34201 aaaaagagtt tggacctctg ggtctgcaaa tttgaggcag acacgccgct gactcagtgc
    34261 cactggtgac ggagaccagc gtaaggctga attgggacta aagtacagta atcactaatc
    34321 acactcctct ctttttcacc ccctcacctg gctgaaaacg gtagatcaga tcgttggtgc
    34381 catgagactt tctgctccct tgcccaacac agcagcgata ggtatactat cttctgatct
    34441 agtgtctggt aaccgtctaa gccttgtcca gctaagctta cttttcgtat cgaccgatcc
    34501 tgagactact tggcagtgtc ggatgccatc ctgaaatccc tcgttgtctc cccgaggcag
    34561 tccagtccga ccgaatgact tcctgggtcg ggcttggcat tacgatctaa caaacgaggg
    34621 tctggttctg gcggggacca aatggcaaac ttttctctct agtcttgtaa ccatgccatc
    34681 gtggaccctc ctatcttgca tgaaagaaaa aagtcgctag ctgctgaggg cgaggctgag
    34741 agcgggtata gttatggaga aagtttagtt ggtcagctgg tctttcaact taatcgtacg
    34801 aaaatctatt ggaactatat ttcggaagaa cacaggcttc ccgcggcaag gcaatatgat
    34861 gaggtgggcg ataccaaaga aacgcacagc tgttcatttc atcaagcttt acgaacaccg
    34921 catggtttac tgaccactac attcgactga ggctcgagct agctcagaga aatagagggg
    34981 agcaggagtt cgctttagat atcgcccagg gcagtgctgg agggggtagg tggtggatac
    35041 ttccttcgtc cgtccagctg agccctaagg tgtataacta gctataccta tcacaagata
    35101 ccagtaagta ggtgggtgcc ctgtgtaagt gccccttgaa attaagaaaa ctgtacgttg
    35161 tgaactactt tgggcgtaga tacttcaact agtactggcc atttgatgta gcgggctagc
    35221 agcggcagtc atcatttgat gtgagtgcaa tttattaagt accataacat tctggaaatt
    35281 ggcatagctg gtgctccctt ttccacacac tgaggttcct taactcgacc caatgtaatt
    35341 aaatgtctcg atcatttccc tactagcgct tgtcggcgtc tagatttgcc ttgtcgccgt
    35401 tgagacaatg gcgctaggac attctctcca gcgccgacga gaataatctt atctaattcc
    35461 tactatgccg aagccccttc gggcattccc cgtcatgtga acctgcagca gatttgaata
    35521 cggataattg gaactgaagc agtcgggctc catcagttcc gagcgcgccg tagggctgac
    35581 ctgcccgcga tttagcggga tgatccaagg ttggatgacc tgttcaccca atccagaaca
    35641 gtcggtggct actggaccct gtcaactgac tgttctgaat aatacttaaa aagcagttac
    35701 ctgaacagta acgacttcac caatgcagag aggcaaagtg gtctgacatc atcatcatca
    35761 tcatcatcat ccctttcaac tagttatgat gatgtatctt aaaagtgtag gatgtctcta
    35821 ctcgggtcaa acaactagct atttggtatt actatgtaaa gtactagcta aagcgactgg
    35881 aaacgatatg gctagtatcg agtaaaaact cttcttcaga acagtttacc aatcgactag
    35941 gtttccaccc actcgccact ccaattatgg agactcaaac cggcatggtt tcatttggtc
    36001 cccctcacag tccacaaaca ttacgtagtt gtgcagtggt ggatgctgaa taagggggac
    36061 ttatgcgtgc cgaggattcc gaccgatcaa tccacagtcc gtcatcccgt ctggtgagct
    36121 tcgacgcgtc ttgccttctc cagatcccct ttagctttac ctcggtttct ttgtcatgat
    36181 tatgtcgggt tgatcaaaaa tccctctttc taaggtgaat gggcgaatgg gaacctcctt
    36241 ggcgaccaat tatcggtttt gacagtcatc ttacgatgtt tgcaaatctg gtagctgcac
    36301 agaactagtg aaaattacac acgcaagtac tgcctggtga ccatgagctc ctctttgagc
    36361 tccccagcga caagtcgccc gagtctcctt aatccccgcc agcccatcaa ggcgttgacg
    36421 gtagctttct gtctctggaa ggctctagta tatctggtca tcatcagttg ccctggcctt
    36481 ggctacgaca cttccacaag ccatctctac catagccaca gtcgccctga tgtcacctca
    36541 gaagacatca cttatgcgca ccttcccatc ccgcttaagt tcgtccggtg ggattccgtt
    36601 tacttcttgc atatcgccga aaatggctat atctttgagc aagagtgggc gtttggctac
    36661 gggtacacta gagtccttgc ctatattgcc actggtagat ctacctgtct tcctcaccga
    36721 aggtgtatcg ctgtgttatt tgagcactaa ttgtggatgt agcattgcaa cgattaatcg
    36781 gccctagtgg agcggccagg accgctgtcg tggcgactgc tctgtctcat attacccatt
    36841 atcttgccgt cttagccttg tatagactct ccgtcaacgt atttggccgt gacacggcca
    36901 ctcaaagact aatctgcttt ctttcagcag ttctgcacgt catttgccct gcaggagcat
    36961 ttctttctgc gccgtatggg gagtctttgt tttctttcct caacatcaca ggtttctatg
    37021 tctactcgtc ctcgtttctc gatagcaagg cggggaagcg tctatccggc gacgtgaaac
    37081 tgctggtagc tgcgatcttg ttctcagcag ctactgcagt tcgtagcaat ggaatcttaa
    37141 gcggtattct gtatgcttat gatgctcttt tgcagcttcg gcgggtttgg tgccaaaggt
    37201 tatcaattga cgcttgtgcc catctctccg ttattatcat cagtggctgt gtcattgccc
    37261 tgggacttgt cgttccgcaa gtcgtggcct attccacata ctgtgtggag gacgatattt
    37321 cacgtccgtg gtgtcaatgg cttgtcccta gtatctatcg ctatgttcaa ggacattact
    37381 ggtacgttgg gatggctgtc aagcaccgca aaacgcacta ctaaaatgaa atacaggagc
    37441 gtaggtttcc ttcggtattg gaccgtctcc aatatcccac tcttcatcct ggcaatgccg
    37501 atgctggcca tactttgccg gtcgtcgcta tgggcactgg atgtggcagt gccctttatc
    37561 tttccgagag ccttaagcgg agtggaccaa gcgtcgtcgt cagccacgac agcctccctt
    37621 cttctccgac tagctgtgcc gcaaggactg cttgccctga tggctctgac ctcttaccat
    37681 gttcagataa ttaataggat atcctcagga tatccactgt ggtactggta cctcgcatat
    37741 ttggtgtcgg gcaactgggg gcaaatgcga ccttccctgc aagacagccg cacctttact
    37801 gtggctgtgc ggggcatggt agcctatgca ctgatccagg ccattctgtt tgggtctttc
    37861 ctcccgcccg cgtga
//
