LOCUS       KZ851921.1             20957 bp    DNA     linear   PLN 20-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   KZ851921
VERSION     KZ851921.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 07:38:58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 236474
            Orig. end    :: 257431
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20957
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[<246474:>247431](-)"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<10001..>10957)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..20957
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20957
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            complement(<868..>1596)
                     /locus_tag="M747DRAFT_342889"
                     /product="hypothetical protein"
     gene            complement(<868..>1596)
                     /locus_tag="M747DRAFT_342889"
     CDS             complement(<868..>1596)
                     /codon_start=1
                     /locus_tag="M747DRAFT_342889"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_342889-T1"
                     /transl_table=1
                     /translation="MAPILLSNNIRTPFRYLNRIIHLRKGEDKGKTRAQPDLSSALTRL
                     FANSENDDEESSITHITESTSQIWVEDQDPALVDLLATLSFTITTSTSDSSTLLALLAS
                     ALDILSTYAQNHKVNTLPIYTALLRHLDTYTSYLIWDHEILLTDAEIIFTASSIPTPKH
                     RDNIILQLESAYVSNYETCKTLVTRLNQLVDIELMERADWIFPRQIGWVEVRREVIRLE
                     KTLKEIRWAGKLKEVEYVNC"
     CDS             join(<6890..6964,7029..7266,7309..7460,7576..8297,
                     8362..9727)
                     /codon_start=1
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR007219"
                     /db_xref="InterPro:IPR036864"
                     /db_xref="PFAM:PF00172"
                     /db_xref="PFAM:PF04082"
                     /locus_tag="M747DRAFT_353846"
                     /note="EggNog:ENOG41; GO_component: GO:0005634 - nucleus
                     [Evidence IEA]; GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_function: GO:0008270 - zinc ion binding
                     [Evidence IEA]; GO_function: GO:0000981 - DNA-binding
                     transcription factor activity, RNA polymerase II-specific
                     [Evidence IEA]; GO_process: GO:0006351 - transcription,
                     DNA-templated [Evidence IEA]; GO_process: GO:0006355 -
                     regulation of transcription, DNA-templated [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_353846-T1"
                     /transl_table=1
                     /translation="MQYPSWPEQPTFRISSTGSHNYSDVGSASHALSSHRAEHPLTSKK
                     MAIPRLAEGLETFSTPGRFHRRHVSRACESCRQRKTKCTGDKSGCRNCREAGIICCYTD
                     DGSVADFREIGTPRQLASLEAKIRTYEDALKNLSSRFGITNEQLMNLALTVEESSSPSL
                     SPDGRTPLPGTQRPLSATSSQLSLYVDSSHCLDCINEDFNKDEISQATGYIGQSSEISW
                     IHSLGRDINGDTEHGTPSEAIFLSISDSSPISASNYHVDDQELPNIERQEAYALPSKDV
                     ASKLYNCYLDWVHPTFPIIGTTPFGKQFHAFFNDTRLHTGNKWLAVLNLLFAIAARYAY
                     ISEAEWQLNKNNHWLYFSRARVLSIDDWSFHHPDLQQLQVEGLTALYMLSLGHVNRAWR
                     ICGSAVRGALGLGLHLRNMSKSASDTSREIRYRVWWSLYTLDHRLSIITGRPSFIDDTV
                     YTTPLPVPFDEKDFGKDEVINCLRFSHGTEGIHTDFDLMGKHSIAISKGTGAISGPPSG
                     SLHFFHVIRLMLISKKMITKLYSPSAASTSWMGIEFAIQGLTSDIESWLLSLPNEFDFT
                     STQSTQVTHSISNHRMSLAFIFYSTKIGITRPCLRRPNPVNQDGKTPDEKIQDFCQRTA
                     AECVESACHMLRLFPDGLDAAALYRMSPWWCILHFLVQATTVLLMELSFGVCHVPEKAS
                     MVSKATERALKWLAILANTNAASEKARLLCEGLLRRIEQYAGVNLPNPPIPSRFGTSVT
                     PGPGPTGLSSAPEPQTNELGCGPLPLSDPSTSLEAHLKGQPASESPDLMHTDKDTTAQD
                     TYDESLPYDPSTGQIIGSFFPPNLGLGLEISEYFLEEV"
     mRNA            join(<6890..6964,7029..7266,7309..7460,7576..8297,
                     8362..9826)
                     /locus_tag="M747DRAFT_353846"
                     /product="hypothetical protein"
     gene            <6890..9826
                     /locus_tag="M747DRAFT_353846"
     mRNA            complement(<10001..>10957)
                     /locus_tag="M747DRAFT_353856"
                     /product="terpenoid synthase"
     gene            complement(<10001..>10957)
                     /locus_tag="M747DRAFT_353856"
     CDS             complement(<10001..>10957)
                     /codon_start=1
                     /db_xref="InterPro:IPR008949"
                     /db_xref="InterPro:IPR024652"
                     /db_xref="PFAM:PF06330"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: TRI5"
                     /gene_kind="biosynthetic"
                     /locus_tag="M747DRAFT_353856"
                     /note="EggNog:ENOG41; GO_function: GO:0016838 -
                     carbon-oxygen lyase activity, acting on phosphates
                     [Evidence IEA]"
                     /product="terpenoid synthase"
                     /protein_id="ncbi_M747DRAFT_353856-T1"
                     /sec_met_domain="TRI5 (E-value: 2.2e-27, bitscore: 89.6,
                     seeds: 3, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTKAQTAVSPDEFFKIITPFLNEIIPNIPPFAPDEAFYKAVFDKF
                     AAASGLPEDSIPHFVGTGEVLARCFYPSLPRDLQISIGVLTAYVFSIDDQCADPEFREQ
                     IKSYRSVFLGQSTTNLQYIKGLYNTLHDIVSHYEWYAGDMIIKSTMDFVSINIVEAEQT
                     GDFMVSPSTKLFPDFLRQKSGIGEAYAFFYFPGSDWGLGDYFTLIPDIAGIIEQLNDVL
                     SFYKESVLGNEPGTWVKQTCVCKGISEGEAFRERVDQCLGSIRRLRAASEGNPRLLKTV
                     NEFINGYPLFHLNAGRYKLDQFGSYHGWQGEKTAGGN"
     mRNA            join(<12810..13609,13666..13690,13747..13801,15379..>16937)
                     /locus_tag="M747DRAFT_316099"
                     /product="cytochrome P450"
     gene            <12810..>16937
                     /locus_tag="M747DRAFT_316099"
     CDS             join(<12810..13609,13666..13690,13747..13801,15379..>16937)
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002401"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="InterPro:IPR036396"
                     /db_xref="PFAM:PF00067"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 212.1; E-value: 2.5e-64)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_316099"
                     /note="EggNog:ENOG41; GO_component: GO:0005887 - integral
                     component of plasma membrane [Evidence IEA]; GO_function:
                     GO:0005506 - iron ion binding [Evidence IEA]; GO_function:
                     GO:0016705 - oxidoreductase activity, acting on paired
                     donors, with incorporation or reduction of molecular oxygen
                     [Evidence IEA]; GO_function: GO:0020037 - heme binding
                     [Evidence IEA]; GO_process: GO:0055114 -
                     oxidation-reduction process [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="cytochrome P450"
                     /protein_id="ncbi_M747DRAFT_316099-T1"
                     /sec_met_domain="p450 (E-value: 3.1e-47, bitscore: 155.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MFHYTLFDIVGHLQFGEELGVLRTGAHKSWVHSQHRLVRAATLLS
                     ALAEFSWINLLFRSTIPWMSKWLRKAYFKPSNDLIDRRLQLQSDEPDLIGLAFRNSRSL
                     SLTEKDIRANAHIMMTGGAETTTALMTALTAYLLQHPECLARLKNDIRTAFHDKSQVSL
                     ESVSNLAYLDACIKEALRLYPSVPGALHRATPAGGARIAGRWVSGNTRVYIPIFAATHS
                     PTHFWSPDKFIPDRWLDGADGPYQKDNKTAFHPFSTGPRGCIGQDMAYAMTKIPLARRS
                     SFMDNMGSATTHVRTKHNEYMATCTEKYSPTPTEVFQDHIASNESDTATLSWDDDNDPE
                     NPYNWSVGRKWTLTCLAAFTTFLAMMNGTIITVAHFEISEHFHVNEDAFPNSYWPVTTW
                     ATGGACSALFILPLAEDFGTRPIFLTTYLLFICFLVPQAVAHNFATLVVTRFFAGGCVA
                     ILANTAAGVVGNLWSTEWSRSIPVSLYILGYMSGSSTGPVIGAAIFHSLGWRWISYMQL
                     IWFGALFPIYYFFLHESRGSAILARRARRNRKNGDETSGYAGSGDVSSRLNLHSLVVSA
                     TRPVILFSTEPVLFVSTLWSAFTVGTLFLFTQSVEQVFMGLYNWDVSQTGYVQCAIVIG
                     ECLGWLVNFLSRKLYFASASRNTEVPGTPIPEARLYMAVVGGVLGLSGGMFIYAWTSYS
                     SLPWIAPTVGLALVGAGSVCVVTGVSDYVVDSYSQFSGSAMGAVAAGENVFSAFLPLAT
                     MSMYRVLGYQWASTLLAFICLVLSLIPTLMFVWGKEVRARSAFMNEMANDATKKRSEVV
                     "
     tRNA            complement(17360..17431)
                     /locus_tag="M747DRAFT_t168"
                     /product="tRNA-Arg"
     gene            complement(17360..17431)
                     /locus_tag="M747DRAFT_t168"
     mRNA            complement(join(17457..18618,18731..19031,19088..19225,
                     19289..19319,19379..19663))
                     /locus_tag="M747DRAFT_324051"
                     /product="amine oxidase"
     gene            complement(17457..19663)
                     /locus_tag="M747DRAFT_324051"
     CDS             complement(join(17573..18618,18731..19031,19088..19225,
                     19289..19319,19379..19509))
                     /codon_start=1
                     /db_xref="InterPro:IPR001613"
                     /db_xref="InterPro:IPR002937"
                     /db_xref="InterPro:IPR036188"
                     /db_xref="PFAM:PF01593"
                     /db_xref="PFAM:PF13450"
                     /locus_tag="M747DRAFT_324051"
                     /note="SECRETED:SignalP(1-24); GO_function: GO:0016491 -
                     oxidoreductase activity [Evidence IEA]; GO_process:
                     GO:0055114 - oxidation-reduction process [Evidence IEA]"
                     /product="amine oxidase"
                     /protein_id="ncbi_M747DRAFT_324051-T1"
                     /transl_table=1
                     /translation="MHTIPITVSLYAFLATTFLFSCSAYVAQAPLSDDKCTETTVAILG
                     GGMAGIAAAQALSNASIDDFIILEYRDTLGGRVWHTDFGKDKQGKPYVIELGANWLQGL
                     GSEAIENPVWALAKKYRLKNTYSNYSSIRTYNETGYTDYRYLLDEYAQAYHIAARDAGR
                     ILTQNLQDQTARTGLALAGWRPRKNDMAAQAVEWWSWDWEDAHTPETSSLVFGIAGENL
                     TFNQFGKANHLVLDPRGYSTIIQNEALGFLPNPSDGRLRLNTRVTRIEYSPRGVTIHTT
                     NDNNKNSNTCIRAAYAICTFSLGVLQNKAVTFDPPLPSWKQTAIEKFNMGTYTKIFMQF
                     PETFWPTDTQFFLYASPTTRGYYPVFQSLSTENFLPESNILFATVVDEQAYRVERQSLT
                     QTKDQILNVLREMFPDKHIPEPTAFTYPRWTNEPWVYGSYSNWPAGTTLEMHQNLRANT
                     GRLWFAGEATSAAYFGFLHGAWYEGRDAGENVAALLQGRCVEDVSTTSTASGKEEKEEA
                     CGERVFYEQLNGTTPLDAYSRLNGWPAVSYY"
ORIGIN
        1 acccagactg aattgatttt cctcttagta gaagcaggca tatgcaccat atgatcttcg
       61 atcacactga tggacccatc attagcgtag ttcccttaag tcgtctcata ctcccttctg
      121 ccccagggta caccttaacg tattctcagt agcgggaaat ccctcattta tgctcgcacc
      181 tataaggctc ttctaaatgc acctctctcg ctgagatgaa ttatacctat gcaccgctga
      241 ccatacccac ccaccctgga caaaataggg accatccatc gttttcatgc gctttcagct
      301 acaccatctt actcaataca ccacaatcac gctggagtct cggtctaacc ccataaccct
      361 tgtttgtatc acactacgtt cgcttactgt gtaacgtatc aacttattat ggccattagc
      421 atcagcagtg caggtgctcc agaatttact gataatgagc agcggggcat ggggtatctc
      481 agaatggtta ttatactatg tagacgtttg aagttgtttg aagtcgttct gacattcgaa
      541 gtgtcaatgt aattaagtac atgggtatca cgtcacagga taggtagttg atttagataa
      601 actcgaaaca cgagtgtagg aaataaagct tgaaagtaaa agaagaagaa aggtacaaaa
      661 gtttcccacc acccgccctg agagagcctg tacatggctc aatctactga ggtagtatca
      721 aagagaagag aggaagagat gagtaaagga gaaagagttg gagtcaggga aggataggga
      781 gaaaggctgg caccgtccag aatagatggg ggaagagaga ggagcgggaa gggaagtaaa
      841 aggaggaaga ggctgggtag aaagacttta gcaattgacg tattcaactt ctttcaactt
      901 gccagcccat ctgatttctt tcagagtctt ttcaagcctt ataacttctc tccttacttc
      961 tacccagcca atttggcgag gaaatatcca atccgcacgt tccatcagct ctatatcaac
     1021 tagttgatta agacgagtta ctagcgtctt gcacgtctcg tagttcgaga catatgcgga
     1081 ttccagctgg aggatgatgt tgtcccggtg tttaggggtt ggaatactgg aggcggtaaa
     1141 gataatttct gcatctgtaa gaaggatctc atgatcccag atgagatagc tggtataggt
     1201 gtctagatga cgcaagaggg cggtatagat tggaagagta ttgactttgt gattttgagc
     1261 gtaggtggat aggatgtcga gggcagaagc aagaagtgca agaagcgtag agctgtcgga
     1321 tgtgctggtc gttatggtaa aggagagtgt ggcgagtaag tcaacgaggg ctggatcttg
     1381 gtcttcgacc catatctggg aagtagactc cgtgatgtgg gtgatagacg attcctcatc
     1441 gtcattctca gagttggcga agagtcgggt tagggctgat gatagatcgg gctgggctct
     1501 ggttttgccc ttgtcctcgc ccttgcgaag gtggatgatg cgattcaagt atctgaaggg
     1561 agtacggata ttgttggaga ggaggatagg agccatctta tagatggtta agatgggtac
     1621 tgaagatttg gttgacaggg cagagggtga atagagtcgc ctatgcagag gagcttttga
     1681 gggaagtcgg tgtctgagat gtttcgggcg gaattttggt agcgatggta tggtctccag
     1741 cggagtttcc aaaggtagga agcttgctag taaactggta gataataggg taggagtgtt
     1801 caaatgataa aacttgaata taatgttgag ggttgtagaa gagatactca gcaatcagaa
     1861 cattagaaac taagaataga cgatatagtt cttgaactcg gatttttctt cccatccatg
     1921 ggtcactttg attcacatag gcttaatata gaaattgatg acatattgac ttcgcaggct
     1981 atactggtca cttcggttcc tgccaggaag cagcgtagtg gtatcgtcac cagcagaaat
     2041 agaagtcatt tggttaatta ggccacaaaa tttggcaaca gcaaatgtac aaagctggaa
     2101 tgcttctcct gagatcgctc gcttcgtctt tatgttgccg ggcgctccca gaatgaagat
     2161 tgcatctttc gcggttttat tctatggaag gggatggcta atggcgttga catgccatag
     2221 ccattaaatc ttgcgactgg cttggcattc caagacggct cctgttgtgc tcttcttgga
     2281 tggaacccta tattaccttt gcctactccg tcgaagaggt caggatccat aatctccaat
     2341 agcagtacga aggtcttcac gacgctctgt cggacctttc attgatatcg gaagatctct
     2401 atcccgcaga tcacaatatt gatgcagcct gcatgcttgt ggttacatcg cgttgaatca
     2461 caccctgcgg tttctatgta atgcccgatg tggatgtttc tggattttat tcccctaaat
     2521 tactaggacg tactcgccca tttcctaaat atcgttttac ttggctttta cgctccttct
     2581 agttgtgccg gatagctgaa tgggtctgtc aatgacaggt atagaagaca cagaagtcaa
     2641 cctttaactg tatactagtc cagttttgtc atagcaaaag ctacgcttgg agatagacta
     2701 acaacagtag gaaatcgaca ttgaatgccc atagcagtca tcctcctatg tcgaaggcta
     2761 gtctgatatc attgcgtcag tgaagcaacc ttcggtattg aacatacgca tatctccgta
     2821 gggaaggagg ccatatcaca gtgccatttc cggttgctac aagttgttaa tagagaggca
     2881 atcttcgaga tgaagaaaag ctccaaaact tacccaatga aattcgtagt cttccagctc
     2941 attatttctg ttacacaggt gttagccatc aggtccttca ccatcggaag gagaagaata
     3001 tcgttaataa gcttaaaccc gccaaagaaa acatatacaa taacgcaaag ctaaacaaat
     3061 gggaatgagc cgatagctcg cccaagttca gaatttattc atgttcttca atcccatcag
     3121 cccagttcac actatacaac ctgatagaga ctgcactgtt gaaatgagct aaccatgcag
     3181 ctttcacagt acaatattaa gaatcgattc atgataatga aaaggtctag agatgtttgt
     3241 atgctacttc catccgcagg cgccggtgga cctgggcttc gggactggtg gagacgtaat
     3301 tgcgtgatga gactatcatt tctcagagaa cccgtgagac atatccttcg ttgccttgcg
     3361 attcgctgtt tatttgtctt ttctatcggc gaagacacca gcagtactca gactggcgtg
     3421 cagtccatag ctgtcgtggg catgggagtg atcagccggt atggcatgct tgctccgtgc
     3481 tgggtacacg aaaatcctca atctctgaat tgtgaggaag tcgttgtgct tttccttttt
     3541 gatgtatctt tcaatacttg tagcagccat ggctcgtaaa agcatttgtg cgagcgtgaa
     3601 atgttgaagt gtgcatattg agactgcatt catggatttc ggttgtctgg caagctctgt
     3661 cgcattaaac taccatgaca cccccggaag ggatcccgat ggaaagtaca gattcgcagc
     3721 gcacaagatg ctcctgcgtc ctcaagagca gcggaccgta gcttagtctg ccaacactga
     3781 gatgagggca acacttaaaa atctcgaatg cccaagtggt catgattgcg cataggagct
     3841 tcgcgagttc taaagctgtc ttcagcgagg tggagaatgc tcctttaccc acgctcatat
     3901 gcaacagcca gtcatcctca actgaagaac agccgcgtga atttccatga cgtcgtgaat
     3961 taggtactac ctataatcca gttccgatta tatatacgtg ccgaacgcaa ccccaagaag
     4021 tgactcaatc attccaaagc tcagaactca ttgatatcgc tgagcctgag gagaatctct
     4081 tatgtatgct cttaaggttt ctagttcatc tgtccctcag cttgcggtgg atgcgccgat
     4141 ggctctcttc gtacgaggca tagcgtcatg gaatcccatt cttcgggcca gaggaggatc
     4201 tgccgtatat gttcagcatg ggtcagttat agtctcatat ccaaagtgat acgtagagca
     4261 tttcgatgtg tcgtgagagt catgaagctt tgggggtaca ccactttcca ttgtacacaa
     4321 tgtggtagag acatcaacgg gtatataggt cgctttatta taacctatcg gactgtaggg
     4381 atcaaatacg taacatgcgt ttcggtgact aagaggctgc agaacttcag atgtgatgag
     4441 aaggaagatt ggatagacag agaaaagcga gggaagcagg gatttatata cccattgtag
     4501 cacacacaac caagcagcgt gaaagcggga cgtgccgtga aagaaaatgt gcgagttctg
     4561 tgactcaaga taatttaacg ggcaaagcca aggctgcatg gttcttcact gtagccttat
     4621 tctctgttta tatcacttcc agcaaccaga ctgcctcatc gagcctcaag gcgtctatta
     4681 cagcagtcaa agtcattcat attccccaca gtccaatatg accgattcct gagaatttgc
     4741 accggtttgc gaaattggta tacaggacaa cgcctgctct atgtcctcca ccaccaccac
     4801 taattcctgc ttcacgaaac cacaacctgg ccaaagcaat caacgcctgt ctgggccagc
     4861 tttcttcatc agtatcactt cagatgtaat tctgttcggt ggatatcacc gatgcattgg
     4921 ttaagagtaa aatggtgggg gtccaatctg gagataataa aactacaaac ttatttcatt
     4981 attctcgtta tgtgtaatca ggctgcagaa catgagcctc tagtccagcc cttgtaccgt
     5041 ggatcaggcc taaggcttta ggtaacatat tcgacacgga aagtggcatg atactgtggc
     5101 aattgacaag gtaaatgtgg agggtaccga tcaactaatg agtgattcga ttttaagtta
     5161 ggagtgtaac gtaggaccat attatcccta taaatctcct gctcaagttt gcacacagcc
     5221 gatgaaattt ccttatggct gaaaggctac ggagatggac tatcaggcta ctccgtgaat
     5281 cgatcacgat gctatggtga aatcgcttgt cacagtatca cagatggtgc accttcgtcc
     5341 tgaatacatt agactatgac taacacgata ctcaatatat ctgcctggga ggggcttatg
     5401 gcagtgtctg ttgtcctggc ccgctaccgc attctgcaac tccagtctcg tccatccagt
     5461 ggacaattgt aaggaattct aaagatcatt tcatctattg tctgttaatt tgaaaagaat
     5521 ctatgtttca ctcaatacgt actttgaact ataattcatc tgctcgagta atagttatca
     5581 tccactacgc atgttaaaac aaagccatcg ggccacatta tatgtacgat tcatgataac
     5641 aaagctttgt gttttttttt tttttattta ttgaattttg actcacttat catcaatctg
     5701 ttttcgaatg gtagtgtcag ttttttctag aaataacaga tattttgatg gtgtacacgc
     5761 gaatgttctt ggatcagtaa actatcacct taagccgctg caaataaccg actacgaaga
     5821 gggtgacccg gatacaggga tatattcggc tggtcgggtc cgaataggca cctaaatatt
     5881 cttcatggag tggaaaattt attctgtatg cgtattagtt gcgcagggca aagtttaatc
     5941 ctctgggcca ttatccagga tttccgctag gctggcaggc acatgacgga gaaactctga
     6001 gaacgttaca tgcagtacag actctgctga tgtcgaccgt ggttcgccca aaggagctaa
     6061 tcactatgag cacattgttt agcttggccc caacgaagat gatggaagta tcctcgtggg
     6121 cccatcacgt actccatatc ctgcctaaat acaacgatga actggtccag atttaacctt
     6181 gtgtcaagcc ctcaaccctc tctcataaca ctgccgtcta gccagtcaaa gaaaatgttg
     6241 cggttacgct tgaagcaaac ggtactcagt gagcggctgg ctaatcatgg tgaataatcc
     6301 gtctacattc cctgcatttt ccggagctgg tagcactcta ccatttcata tccatggaaa
     6361 tcagcggcaa ttctggtctc cctaatacct ggtctcctag agttctcgct tttctggttg
     6421 ataatttggt acctagcatc tagactcaga gacgggccga tcctcggctg gagggaaaca
     6481 agagacacaa gggaagtagc cacgactgcg ctttccgcct gcacttttca ccaaaagaaa
     6541 tcttgttggg gggaaggaac tgatcgaggg ttcgattttt gatgaaccgt gagacgttac
     6601 tctttcaaag ctagtttcac tctctttcgg gctgagttac atccctatac tttcgttgaa
     6661 gaactcagtc ttaaaattat atattaagat tcagctcagc taccttttct gtaaacgtta
     6721 tcgacatcct ctcaattact ctggtgtatc atcctgcaat tgttcaactc tctaaggtat
     6781 cagtgatggg tgacatcaag atgagctctc taaggcgctg ctacagaaca gctactaatg
     6841 attgcttgga cagaattgtg gactttcttc cttagacctt catagcacaa tgcagtatcc
     6901 atcttggcca gaacaaccga ccttcaggat atcctcgacc ggttcgcaca actacagcga
     6961 tgtggtgagg gccatccgat ccccctctcg tctatctacc agtccgaaag ttaactgagg
     7021 atctcaaggg tagtgcatct catgcattgt cctcccacag agcggagcat cctttgacta
     7081 gcaagaagat ggcaattcct aggctagcag aagggctgga aacattctca actccaggta
     7141 gatttcatcg tcgccacgtg agccgagcat gtgaatcctg cagacagaga aagacaaagt
     7201 gcactggaga taagtccggt tgtcgcaact gccgtgaggc tggcatcatt tgctgctata
     7261 cagatggtaa aagggagaaa tccaagaggt gagtctgaat ctgattagat ggctccgtgg
     7321 ctgacttcag agaaattggt acgccaaggc aattggctag cttggaggcc aaaatacgga
     7381 cttacgaaga tgctttgaag aacctgagca gcagatttgg gattacgaat gagcagctga
     7441 tgaaccttgc attgactgtg gtatgaatac aggcccctcg ccttgctctc gttgaaacca
     7501 tatcctttga tcctcttgag cccgttatat cctcttcgtc ctctctcttc gagtgtttat
     7561 actgaccgga agtaggaaga gtcctctagt ccttccttgt cccccgatgg gcgaaccccc
     7621 ttgcccggaa ctcaaagacc tctctcagct accagttccc agttgtcact atatgttgac
     7681 tcaagccact gccttgattg catcaatgaa gacttcaaca aggacgaaat ttcccaagct
     7741 actggttata ttggtcaaag ctccgaaata tcatggatac actcattagg ccgagatatc
     7801 aatggagaca ctgagcacgg tactccgagc gaagctatat ttttatcgat ctctgatagt
     7861 agtcctatct ccgcatcgaa ttaccatgtt gatgatcaag aactgccaaa tatcgagcga
     7921 caagaggcat atgcactacc atcaaaggat gtagcttcaa agctctacaa ctgctatttg
     7981 gattgggtgc atcctacctt cccaatcata ggaaccacac cttttggaaa acagttccac
     8041 gcattcttca acgataccag gttacatacg ggtaacaagt ggctcgcagt cttgaaccta
     8101 ttatttgcga ttgctgctag gtatgcttac atctctgaag cagaatggca gctgaacaag
     8161 aataatcact ggttgtattt ctcaagagcg agggtcttga gtatagatga ttggagcttt
     8221 catcatcctg acctacagca attacaagtg gaagggctaa cagctttata catgctttca
     8281 ttggggcatg tcaaccggta cgtatatcat gtcgggaggt acgaatcggc tattcatgtg
     8341 agtgcttacg aatataccaa gtgcctggag aatctgtgga agtgctgttc ggggagccct
     8401 tggtcttggg ttgcatctgc gcaacatgag caagtctgct tcggatactt ccagggagat
     8461 tcgatatcgt gtatggtggt ctctctacac gcttgatcac cgacttagca taatcacggg
     8521 acggccttcc ttcatagatg atactgtcta tacaacacct ctgccagtac catttgacga
     8581 aaaggatttc gggaaggatg aagttataaa ttgcctccgg ttctcacacg gaactgaagg
     8641 aattcataca gattttgatt tgatgggcaa acactcaata gcaatctcca agggtacagg
     8701 cgcaatttcc ggtcctccct ctggatcgtt gcacttcttc catgtcattc ggctcatgct
     8761 gatatcaaag aagatgataa ctaagcttta cagtccctca gcagcgagca cgtcttggat
     8821 ggggatagaa ttcgccatac aaggtcttac atctgacatc gaatcatggc ttctgagcct
     8881 tcctaatgag tttgacttta cctcgaccca atccacgcag gttactcatt cgatatctaa
     8941 ccaccgaatg agcctggcat ttatattcta tagcaccaaa attggaataa cacggccatg
     9001 tctgcgccgt cccaatcctg tgaatcagga tggcaaaact ccagatgaaa agatacagga
     9061 tttctgtcag agaacagcag ctgagtgcgt ggaatcagct tgccatatgc tgagattgtt
     9121 cccagatggg ctagatgctg ctgcgctgta cagaatgtca ccttggtggt gtatactgca
     9181 ttttcttgta caagcaacca cggtcctttt aatggaactg tcttttggtg tttgccacgt
     9241 accagagaaa gcatcgatgg tttctaaggc gaccgaaaga gcacttaaat ggcttgctat
     9301 actcgcaaat accaacgcgg cctcggagaa agctcgctta ctatgcgaag gtcttttgcg
     9361 ccgtatcgaa caatatgcgg gcgtgaattt acccaacccg cccatcccta gcagattcgg
     9421 cacttctgtt acgcctggac ctggaccaac cggactttcg tctgctccag agccgcagac
     9481 taatgaactt ggatgtggtc ctctaccgct ctcagatccg tcaacttctc tggaagccca
     9541 tttaaaaggc cagcctgctt cagaaagtcc cgacctcatg catacggaca aggataccac
     9601 cgctcaggat acttacgatg agagccttcc ttatgatcca agcacagggc agatcatagg
     9661 gtcctttttc ccacctaatt taggactcgg cttggaaata agcgaatact ttttggagga
     9721 agtgtgacac ttgcgtacac ctcgtgatca gtaatgaaat caaaggactg tcctctcttt
     9781 gagtcttgtg aaaggtatcc tagtattgtg ctgtgaaagt ttgagcaacg cggccctgtc
     9841 actctcgctc cgccttagta tatagaatcg tgatggcccc caaattgcaa tgaacgtccc
     9901 tcttcacgtt gttgacacca gtatattctt agtcttaaat gctttgaccc gagttcaatc
     9961 ttattccaat cccttccagc tgcgttggcc tgttatacta tcaattccca cccgccgtct
    10021 tctcaccctg ccaaccatga taactgccaa actgatccag cttataccta cccgcgttaa
    10081 gatggaagag aggataccca ttaatgaact cattgactgt ctttagcagt ctcggatttc
    10141 cctcagatgc agcacgcagt ctccgaatac tgcctaagca ctgatccact ctctccctga
    10201 aagcctcacc ttcagaaatc cccttacaga cacaagtctg cttaacccac gttccgggct
    10261 catttcctag aacagactcc ttataaaacg acagcacatc attcaactgc tcaataatac
    10321 ccgctatatc ggggatcaac gtaaaataat cccccagacc ccaatcactc ccagggaaat
    10381 aaaaaaacgc ataagcctca ccgataccac ttttctgtcg caagaagtcc ggaaacaact
    10441 tggtagatgg agagaccatg aaatcaccag tctgctccgc ctccacaata ttgatactca
    10501 cgaagtccat ggttgatttg atgatcatgt caccagcata ccactcatag tgactgacta
    10561 tatcgtgaag ggtattgtat agacccttga tatactggag gttcgtggta gattggccga
    10621 gaaagactga gcggtacgat ttgatctgct cgcggaactc ggggtctgcg cattgatcgt
    10681 cgattgagaa gacgtatgct gttaagactc ctatggatat ttgtagatct cggggtaggc
    10741 tggggtagaa gcatcgtgct aggacttcgc ctgttccgac gaagtggggg atgctgtctt
    10801 ctgggaggcc ggaggcagct gcgaatttgt cgaagactgc tttgtagaat gcttcgtcgg
    10861 gcgcgaaggg cgggatgttg ggaatgattt cgtttaggaa gggggtgatg attttgaaga
    10921 attcgtcggg tgatactgcg gtttgcgctt ttgtcattgt tgcagaccgt gctaatggtt
    10981 atggtgttgt gggatgtact aggtattggg aaggtactat taaagcggat gagtgtagtt
    11041 ggagctgttc gtcaaaaaaa acatttcact acgtcattag gttgccatat cggattcatc
    11101 gcacattctc aaggacaata atggtgtctg tggctttgat aagaaagtca atgtcgtcat
    11161 atcgttgata tgactggcgt tgacattgga gcaagaggca tttgcacagc tttgtcacac
    11221 tgacgaaaaa gtatgggtga gtttgccatg agacatctgc atgcaaggat ggtcatgttg
    11281 tgtgagatga catggatgaa taatggtata gacaaatgag atgatgtttg cgcggtaagt
    11341 gcaagttaat ggcttatgca caagctactc agaatgaaag agatcagcaa gtgttcagcc
    11401 gtggggattt gcagatatgc atcctcgacg tatgatgtgc ttgtgggtcg aggaatgttg
    11461 taagcttgca agagtatagg ctgatctctg gatgggtgtg ctttgtatct caaccgttct
    11521 gctactacac cctaattagc gtacaagacc atcaataggg tattgatctt ttgacggtga
    11581 aaatgaccgg gggactaata gcaagtgtcg tgctgtccga gttagcaagg gaaatccagg
    11641 tgctcgcttc aaggaggtat agaacattgt gtgacagctc tgcatccgtc ctatttgggc
    11701 actatgataa tccatctctg tgcattgctt ctgtcaaggt tttcttcaag atactaaccg
    11761 atatgagtga tttgaatttt tggctatagc gaggcggctg ctttgacatg agatagagga
    11821 accattatta ttgctcaccc agcagacagt gatttcttct gctaatatat agcccttggc
    11881 tatggaataa tcatgtatgc ctcttatggt tccagcggtg gttgatgtaa ggggtttatg
    11941 gaataatgag gtcggttaca caaggtcaca ggaacatcct actcacaccc tggatcgtcc
    12001 tgtttgaaaa acttaccact tgtagatcga cttttgatga cttcccatgc ctcgtgtaga
    12061 tgcagttatt cgactctgaa aatagttggt ggagataact tttctacgag caagtcaatc
    12121 taccactctg cattgttctc tcactccctc tatttgatat aacactcccc gtcgacattt
    12181 aaatggcctt gcacgacata tcttcggagc caagatgccg gaagaaaacg tggcaagcat
    12241 tcttgtggca acagggattt ttctggtcag ttatgaaagg ctgctattct tcagaagata
    12301 cttcagtgat tgagagaact aagaccgaga gtgatctata gtacctatca atggttactt
    12361 ataatctgtt cattcatcca ctgaaagagg tccccggccc gcgaatgctg gccgccagca
    12421 ggattcccgt gacttatgcc tcactcaagg ggattcaaac acagtggctc cataaccttc
    12481 atctcaaata tggaccagtc ctacgtgttg ctccgaatga gctgagcttt atcgacccac
    12541 aagcctggaa agacatatat agcagttctc ccactgagcc acagagtatg cggagagggt
    12601 cggacttttt cagatatctt gaggatgatg acaatcggcc ctctattctt gcggccaatg
    12661 aaatagacca cccaagaatc cgtcgagcat acgtaccggc attttcacgg cgagccttag
    12721 cccgccagga atcaatcctt gccaagtatg gcgacgctct cgttgaaagg ctttctggaa
    12781 tagaagggca aatcacaaat atacgcaaca tgttccatta cacgcttttt gacatcgttg
    12841 ggcatttgca gtttggcgag gaattgggcg tcttgcgaac aggagcacat aaatcgtggg
    12901 tacacagcca gcacaggctg gtacgtgccg cgactttatt atcagctctc gctgaattct
    12961 cctggattaa ccttttattc cggtcgacca taccctggat gtcgaaatgg ctccgcaagg
    13021 cttacttcaa gccttcgaat gacctcatag accgtcggct tcaattgcaa agcgacgaac
    13081 cagaccttat cggccttgca tttcgcaaca gtcgcagctt gtcgttgact gaaaaagaca
    13141 tccgtgccaa cgcccacatt atgatgactg gaggagcaga aacgaccaca gcgctcatga
    13201 cagccttaac tgcatatctc cttcagcacc ctgagtgtct tgcgcgtctc aaaaatgaca
    13261 ttcgcacagc atttcacgat aagagccagg tatctctgga atctgtgtcg aatctcgcgt
    13321 acttggatgc ctgtatcaag gaggctttaa ggctgtatcc ctcggtccct ggagctttac
    13381 accgtgctac ccctgcaggc ggggcgcgca tagccggtcg atgggtctca ggaaacacgc
    13441 gggtctatat tccaattttt gcagccacac attcccccac ccacttctgg agccctgaca
    13501 aatttattcc tgatcgctgg ctagatggtg cagatggccc gtaccagaaa gataataaaa
    13561 cggcatttca tccattttcc acaggtccgc ggggttgtat tggtcaagag taagtgaacc
    13621 taatacctat tatgcatgaa attgtctaac tgatatgtaa aatagcatgg catatgccat
    13681 gacaaaaata gtattctgca aatttgtaac ggagtttgac tgtgaacttg cagttaatga
    13741 atctagcccc tggctcgcag gtcatcgttc atggacaaca tgggaagtgc caccactcat
    13801 ggtgcgtgta tccaggtgca agccagcaga aaaggttagc agctgattgg gatataatat
    13861 tgggatatga cgttcgtgaa acatgggaca tggaaagaat gacgatgtag tgataacctt
    13921 gagtatggtc agtttgtcgt gtcatctttg tacttgacta tccttctcgt tgtggccaca
    13981 ggtgccctag atgcatctca tatcagcttc gtactcagca catctcaaga gaaagggaaa
    14041 gaatgttatc aatggaaaag aagaaatgaa taatacatta actagctcat tcgaatccgg
    14101 gccggcttga atatgatatc cgtaaagacc gtaacggtat ttctgggtcc aacaccgtgg
    14161 cctataatta cagtcccgcg gtggctggtt gcccgtggtc cacggcccaa ctgtcagttg
    14221 gtcttcggct tcactgtatc tctgggatgc gcggatgcgc caaaccgaag ttagtttaac
    14281 ttattttgtg gtctggattc agcctgtccg cgggtatggc ctaagttaca atgtacatat
    14341 gccttcgggt gcctttccga gataccctcg ggatcatcca ggcgtcgggt tctcgattag
    14401 gaagtgaagg catgggctgc tcgggaagaa tgattgactt ggcagatatg cagtgaagat
    14461 catcaagccc aatgcgggcg aaatccgtag agttcttctg gttctccgat cgttcaccta
    14521 attgagttag cagtaactca gtctgctgag gctcagattc tcattcttgt catagattag
    14581 cgggcgcgca tttgcacgca ctccgatatt cctacttgta agatggtgtt ctagactgat
    14641 tagcccaata tactagtctt aaaacgccgt gtgaaccatt ggctcgtgaa ctggacttca
    14701 gtcggatctt cgtcagctgc taatagtcgc ttttcggcac attcttagta aggaaagtca
    14761 cgcaagttgc attcccaagc ataaccgatg catatcggga caatgatcat tgtagcctgg
    14821 cattctacca gaccgtgatc cggtacctgc aagttcgtgg cttcatcgtc gcatagtaca
    14881 gctgttcttt ctcatcgccg gtatcactag gatcttgggg atgtaattaa tagctacaaa
    14941 aaacatgcat catggtaatt atgatcatta ttacgcttta cagtcatact aggtctacaa
    15001 agtaactcca agtaatgcag ggcattcaat gtccacaatg ggcctgttgg accgttttca
    15061 ttttctcggt tcaaggttgc cgactgatac cactgtgttc acggcggcta atcggctcac
    15121 gaacccgaag tcaagcgagt taccgcaaag ttgcatccat cagccttccc gatagggctc
    15181 cgctgcatca agccaagact ataagtaact atcaattaac tattcccaaa aagggcacta
    15241 ttgtgagaag caagacgctt cacaaagccc tggatatgtt gctgtcaatg atatataggt
    15301 catacagtag ggtccatagc catatggcgg atgattacta tctctatttg acatacactc
    15361 gtgaattatc gtgagcagta agaaccaagc acaacgaata catggcaacc tgcacagaga
    15421 aatattctcc aaccccgacc gaagtcttcc aagaccatat cgcgtcaaat gaaagtgaca
    15481 ccgcgactct ctcttgggat gacgataatg atcccgaaaa cccctacaac tggtcagtgg
    15541 gacggaaatg gaccctgaca tgcctcgctg ctttcactac cttcctggcg atgatgaacg
    15601 gaaccatcat tactgtggcg cacttcgaga tctcagaaca cttccatgtc aacgaggatg
    15661 catttcctaa ttcttactgg ccggtaacaa catgggctac cggcggtgca tgctcagctt
    15721 tattcattct tcccctagca gaggatttcg ggacgaggcc tatcttcctc acaacatatc
    15781 tattatttat ttgcttcctg gtgcctcaag ccgttgctca taacttcgca acattagtgg
    15841 tcacccgctt tttcgccggc ggctgtgtcg ctatcctggc caataccgcc gccggtgttg
    15901 tcggaaatct atggagcact gagtggtcca ggtccatccc agtcagtcta tatattctcg
    15961 gttatatgag cggcagcagt acaggccccg tgattggcgc cgcgatattc cactctttag
    16021 gctggaggtg gattagctat atgcagctca tttggttcgg ggctctcttt ccaatctatt
    16081 acttcttcct tcatgagtcg cgtggcagcg cgattcttgc acgacgagca cgacgtaatc
    16141 gcaagaatgg cgacgagacc agcggttatg cagggagcgg ggatgtttcc tctcgtttga
    16201 acctgcatag tcttgtagtc agcgcgacaa gaccggtgat tttattttct acggagccgg
    16261 ttctcttcgt gtcgaccctt tggtccgctt tcacagtggg gactcttttc ctctttaccc
    16321 agtccgttga gcaggtgttc atgggcctat ataactggga cgtttcacaa accggttatg
    16381 ttcaatgcgc catcgtcatc ggagaatgtc taggctggct agtgaacttc ctttctcgga
    16441 agctctattt cgcgtctgct tccagaaata ccgaggtgcc gggaactcca atcccagagg
    16501 cgaggctata catggctgtg gtgggagggg ttctcggtct ctcgggcggt atgttcatct
    16561 atgcttggac ttcatattcg agtcttccat ggattgcacc tactgttggc ttggccttgg
    16621 taggtgctgg cagtgtttgt gtcgtgactg gagtatcaga ctatgtggtc gactcttaca
    16681 gtcagttttc aggaagtgcc atgggtgctg ttgctgcggg agagaatgtc ttctctgctt
    16741 tcttgcccct cgcaacgatg agcatgtacc gggtgctagg atatcagtgg gctagtacgc
    16801 tacttgcctt tatttgcttg gtgttgtcgc ttatacctac attaatgttt gtctggggga
    16861 aggaggtacg tgcacggagt gcttttatga atgagatggc gaatgatgca acgaagaaac
    16921 ggtcagaggt tgtttaaggt agctattggc agaaacacga actagcgatg gatgcaatag
    16981 cgaattgggc aacattattg cttcagacgg tgaagggcgt tcaggctgga cggttggtag
    17041 ctactactga tcctagaatg aagtagtagt tgcccgaaat atatactatt gatagcatac
    17101 tagtagtttg aggggattaa tacgacattg aactccattg ggtagcacct tgctaggaga
    17161 ctatgatgag aattatgcat atgctataac aaaggacagg aaccgactta agatgccgat
    17221 tcataccaca ccccccaaag aaaacctgag cgcagagaaa ggcgactgta cgagtagata
    17281 atttccagcg atagtacccg tacggaaggc gccccaccgt accagatcca ctctccacct
    17341 aagaaaaaag caaaaagaat gacctacgca ggactcgaac ctgcaatctc ttgatccgta
    17401 gtcaagcgcc ttaccattgg gccagcaggc cagttgatgt ataatcccaa attattgcgc
    17461 tacatgatgc agactaatat gaaattccaa aaaagtaatt tcccatgcca acgccattca
    17521 tccatccaat ctatccaaca actaaagcag accctacaaa gccataccac ttctagtagt
    17581 aacttaccgc cggccacccg ttcaaccgac tatacgcatc cagcggcgta gtcccattta
    17641 attgctcata aaagaccctc tctccacacg cttcctcctt ctcttctttc ccactagcag
    17701 tactagtagt actaacatcc tcaacacacc tcccctgcaa cagcgcggca acattctcac
    17761 ccgcatcgcg cccctcatac cacgcaccat gcaagaaccc gaaatacgcc gcactggtcg
    17821 cttcgcctgc gaaccacagc cggcccgtat tcgcccgcag attctgatgc atctcaaggg
    17881 tcgttcccgc cggccagttg gagtagctgc cgtagaccca gggttcattc gtccagcggg
    17941 ggtaagtaaa cgccgtaggc tcagggatgt gtttatcagg gaacatctct cttagaacat
    18001 tgaggatctg gtccttcgtt tgagtcaagg attggcgttc aacgcggtag gcttgttcgt
    18061 cgaccacggt ggcgaagagg atgtttgatt cagggaggaa gttctctgtg gagagggatt
    18121 ggaagacagg gtagtagcct cttgttgttg gggaagcgta taggaaaaat tgcgtgtctg
    18181 tgggccaaaa ggtctcaggg aattgcatga atatcttggt gtaggtgccc atgttgaatt
    18241 tctcgatggc ggtttgtttc caggagggca aaggtgggtc gaaggttacg gctttgtttt
    18301 ggaggacgcc cagggagaag gtgcagattg cgtaggccgc tcggatgcag gtgttgctgt
    18361 ttttgttgtt gtcgttggtg gtgtggattg ttacgcccct tggggagtat tcaatgcgag
    18421 tgacgcgggt gtttaggcgt aggcggccat cagaggggtt gggtaggaaa ccgagggctt
    18481 cgttttgaat gatggtgctg tagccgcgcg ggtcgaggac gaggtggttg gctttgccga
    18541 attggttgaa ggttaggttc tcaccggcga tgccgaagac caaggagctg gtttcgggcg
    18601 tatgtgcgtc ttcccagtct agttttggga tatgcgttag tcgagggtgg gctatgggat
    18661 agggttggtg ttgacccgat gggtgtaaaa agggttgggt gttccccctc ttaatggtaa
    18721 ttgttcatac cccagctcca ccattccacg gcttgtgccg ccatgtcatt cttgcgtggt
    18781 ctccagccgg cgagggcgag cccggtgcgt gcggtttggt cttgtaggtt ctgggtcaga
    18841 atgcggccag catcgcgggc ggcgatgtgg taggcttgcg cgtattcgtc gagcaaatag
    18901 cggtagtcgg tgtagccggt ttcgttgtat gttcggatgg agctgtagtt agagtaggtg
    18961 tttttgagac ggtatttttt ggctagtgcc cagactggat tctcgatagc ttcggagccg
    19021 agtccttgga gctgttgtta tggtgaggcg gatgttcatt tgacgggatg tatgcagatt
    19081 gtcataccca gttggctcct agctcaatca cgtatggctt gccttgttta tccttgccga
    19141 aatccgtatg ccagacacgg ccacctaggg tatcgcgata ttcgaggatg ataaagtcgt
    19201 cgatagatgc gttggacaag gcttgctaga ggtgttggtg agcattgccg gtcggggttt
    19261 agggcaaagg ggcctgaggg tcacctactg cagctgcaat accggccatc cctccacccc
    19321 tgttaacgtt agacgctaag ctctaacacg atatcaagca ttagtgggaa gctcctacaa
    19381 gatggccacc gttgtttcgg tgcacttgtc atcgctcagc ggtgcctgtg caacataagc
    19441 ggagcaggag aacagaaagg tcgtcgctag gaaggcgtat aaagaaacgg tgatgggtat
    19501 cgtatgcatg gcaggtgagt gacgtctacg aaaagcggaa gaggatggca agtgtagtat
    19561 ggtatatagt attcactcag ttctgcatta gactgattgc ttgctatgca ctggtagtag
    19621 tagtaagtaa aactggccgt agtgagaacg gcagctgcta caccagggag gatagggggt
    19681 caaattaagc ctagaagacc tggcatggcg ggctggtcag ccggacaagg gccagctcaa
    19741 atagtcaggc atggacccaa agagggaagc aaaagcaaaa gcatcaaatc aatagtgtgt
    19801 ctgcacggaa gggcaaggat gatcggtgaa gggctggagg ggagcgcctt gtgatcggga
    19861 caggcatctt ggcgcacggc caaggcagga ggcgtaccac gtgaggcgtt ccgcgacaag
    19921 cttctggaag gcgattcgga gacccgcgca tccattcttc aagggatgaa agccgcgcac
    19981 tggaataagc cggtggtttg caccagacag gaatgtccag gcgggtgagg cgggcatcgc
    20041 tcctgattgg ctggcaatgt ttgataaggc agcgataagg agataaggca cccccacctc
    20101 gaaatgggcc ggtgggtgcc tggggccgcc attgcggata gatcctgatc tgccctcttg
    20161 gtgtgacgcg caaagaggat tgggcgatgc ttgacttgac cagccgcggg tagattaagc
    20221 ttccccgcat gaggttggac ataccccttt gatccatagc ttcccttagc tccatattac
    20281 ccctctccct gcgatttaag ctgccagtaa cctcatgtcg cacatcaagt ccatcatccg
    20341 ccaaaatatc ccgtcaacaa ctccctcgga ctgactcttg gccatggaag aaatgaaagt
    20401 cgcccgcgat gggcccgagg atgatgtcca actggccgaa atgggtcata aacccgagct
    20461 gcaacggaac ttttcgacct tgtgtgtact acctaatcct agatgacccg ggggaagaaa
    20521 ccctattgac ccgagattag gtctatgctt ggactggcct ttgcggtgct taatgtgcgt
    20581 cttctgctgt gccaacgggc cgatcacacg tgctgataat ctgccgatta gtcttggacg
    20641 gctctatccg cgagcttatc cctcagctta ccctcagggg gaagtactag tgtcgtctgg
    20701 ggtgggtatg ccaatggaac tagctgcctg tttaggtttg ctaaccccca gtcacaggtt
    20761 tggtcacggc cggattctgc aacctctgta ttgcagtgtc gctagctgag ttcttgtccg
    20821 catatccaac gtaagatcca tcagaatagc ttggtttgct agtgggtgag tgactgacga
    20881 ggatgtatca gggcgggggg ccagtatcat tgggtagccg gtatgttttc ccgcagtaac
    20941 tgctcaggtg ctatact
//
