LOCUS       KZ851945.1             21300 bp    DNA     linear   PLN 20-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   KZ851945
VERSION     KZ851945.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 07:38:58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 50986
            Orig. end    :: 72286
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21300
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[62181:>62286](-), [62094:62113](-),
                     [61890:62039](-), [61829:61845](-), [61601:61767](-),
                     [61464:61554](-), [61386:61420](-), [61108:61326](-),
                     [<60986:61062](-)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(join(<10001..10076,10123..10340,10401..10434,
                     10479..10568,10616..10781,10844..10859,10905..11053,
                     11109..11127,11196..>11300))
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..21300
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21300
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            complement(1731..2807)
                     /locus_tag="M747DRAFT_299163"
                     /product="ribosomal protein L27"
     gene            complement(1731..2807)
                     /locus_tag="M747DRAFT_299163"
     CDS             complement(1900..2751)
                     /codon_start=1
                     /db_xref="InterPro:IPR001684"
                     /db_xref="InterPro:IPR018261"
                     /db_xref="PFAM:PF01016"
                     /locus_tag="M747DRAFT_299163"
                     /note="BUSCO:EOG09264ZDZ; GO_component: GO:0005840 -
                     ribosome [Evidence IEA]; GO_function: GO:0003735 -
                     structural constituent of ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /product="ribosomal protein L27"
                     /protein_id="ncbi_M747DRAFT_299163-T1"
                     /transl_table=1
                     /translation="MFQPRLLAPLRALERGLTRTPTAATTSIRNTSSLLRNTSSILSAT
                     SITQTKLTPLASPTLHQFLQVRHASHASQGTANRHSRDPAGKRLGAKRTAGEYVVPGCI
                     IFRQRGTKWFPGENCAMGRDHTIYAAEAGYVRYYLDPERHPDRKYIGVVFEKEGKLPTP
                     KNAPTRRKLNRVAVRFEPEEELAAKQGDLVAKIGEEGTQVGSATKVEAAQAAVQLRPGY
                     MYREANWSIGRAAEKAGITAKPYNRKNRWLAWRKRTAKAERMAQMKSLKNKKKGAKKKG
                     GK"
     mRNA            join(2940..3186,3239..3806)
                     /gene="LCL2"
                     /locus_tag="M747DRAFT_334884"
                     /product="Long chronological lifespan protein 2"
     gene            2940..3806
                     /gene="LCL2"
                     /locus_tag="M747DRAFT_334884"
     CDS             join(3003..3186,3239..3432)
                     /codon_start=1
                     /gene="LCL2"
                     /locus_tag="M747DRAFT_334884"
                     /note="SECRETED:SignalP(1-20); EggNog:ENOG41"
                     /product="Long chronological lifespan protein 2"
                     /protein_id="ncbi_M747DRAFT_334884-T1"
                     /transl_table=1
                     /translation="MFSWIRLLGALLLLASVAHAQFQFFEHMFGGGGGGGGHQGRQQAA
                     QNVPSDSSRYQSQWDSAHCDKYLCPGTLACVHFPHHCPCPHPDVEEKVELGEGSAVCVS
                     KGGYKEGEAARKIELARKGLL"
     mRNA            join(4404..5024,5072..6527)
                     /locus_tag="M747DRAFT_299165"
                     /product="scramblase family protein"
     gene            4404..6527
                     /locus_tag="M747DRAFT_299165"
     CDS             join(4500..5024,5072..6163)
                     /codon_start=1
                     /db_xref="InterPro:IPR005552"
                     /db_xref="PFAM:PF03803"
                     /locus_tag="M747DRAFT_299165"
                     /note="EggNog:ENOG41; GO_function: GO:0017128 -
                     phospholipid scramblase activity [Evidence IEA];
                     GO_process: GO:0017121 - plasma membrane phospholipid
                     scrambling [Evidence IEA]"
                     /product="scramblase family protein"
                     /protein_id="ncbi_M747DRAFT_299165-T1"
                     /transl_table=1
                     /translation="MWSALRTPPAQCLRAPGRALASSLRGRPNPRGPRNSIRRPEPIRR
                     DVPASRAPEPSNTETSPENPTPQYDPSQNTLLAPVHIPEDPHGVIKETHPATGILANSG
                     LVVQRQLELMNVMIGFEQANKYVIMDANGNHIGYMAEQEKGMVNMMARQSFRTHRSFVT
                     HVFDKHENEVLRFHRPFSWINSRIRVYDPLDLAKGAYSSSTALQATSAGSLVQPTGDSN
                     ARVSSLGLDEIRVIGEAQQQWAPLRRKYNLFTYHHSPNPATEMKTEKLPLNQMDLSNKQ
                     QMQLVQSSQSGQETGEYHQFAYVDEPFLSWDFGLRSADKQLIGSVNRNFAGFAREIFTD
                     TGVYALRMDSASPSEEFLDKNRAATGMTFDQRAVMLATAVSIDFDYFSRHSNSGGFGFM
                     PLWIPGFGGEAAAGGAAGGAAAGEAGAVGEAAAGTLGRAGAAGGMADGAAAGAAGAGAM
                     AGYEAMSRGMGGSQPAPDQQAAPVDQQPPTPGQTGPYGDVWGEESENPWGKEPENTWGQ
                     EEDPWADEADEGEGGDDFDWF"
     mRNA            join(6645..7234,7351..7930)
                     /gene="UBC7"
                     /locus_tag="M747DRAFT_287921"
                     /product="Ubiquitin-conjugating enzyme E2 7"
     gene            6645..7930
                     /gene="UBC7"
                     /locus_tag="M747DRAFT_287921"
     CDS             join(6988..7234,7351..7604)
                     /codon_start=1
                     /db_xref="InterPro:IPR000608"
                     /db_xref="InterPro:IPR016135"
                     /db_xref="InterPro:IPR023313"
                     /db_xref="PFAM:PF00179"
                     /gene="UBC7"
                     /locus_tag="M747DRAFT_287921"
                     /product="Ubiquitin-conjugating enzyme E2 7"
                     /protein_id="ncbi_M747DRAFT_287921-T1"
                     /transl_table=1
                     /translation="MSSVAQKRLFHEYKNLSTNPPEGITAGPVTEDDMFHWEALIQGPE
                     GTPFEGGVFAAELKFPKDYPLSPPTMKFVGGGVWHPNVYPNGTVCISILHPPGDDPNHY
                     EHASERWSPIQSVEKILISVMSMLAEPNDESPANVEAAKMWRERRGEYERKVRDEVRKG
                     LGL"
     CDS             complement(join(<7933..8412,8464..8535,8593..8673,
                     8723..8809,8865..8973,9032..9098,9146..9437))
                     /codon_start=1
                     /db_xref="InterPro:IPR002815"
                     /db_xref="InterPro:IPR013049"
                     /db_xref="InterPro:IPR034136"
                     /db_xref="InterPro:IPR036078"
                     /db_xref="PFAM:PF04406"
                     /locus_tag="M747DRAFT_359727"
                     /note="GO_component: GO:0005694 - chromosome [Evidence
                     IEA]; GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016889 - endodeoxyribonuclease activity,
                     producing 3'-phosphomonoesters [Evidence IEA]; GO_function:
                     GO:0003824 - catalytic activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA]; GO_process: GO:0000737 - DNA catabolic process,
                     endonucleolytic [Evidence IEA]"
                     /product="meiotic recombination protein spo11"
                     /protein_id="ncbi_M747DRAFT_359727-T1"
                     /transl_table=1
                     /translation="MEASHLDGMEAEAFERLTIIATIPQTPVQSYIQETLAAILDEVSF
                     REGHLSITLKQRGKKFASLFINPRTLALETSEIQTYTTYRWPGGDMNEALKFTAALRVL
                     AAIAEAVQAGLVVSKRDIYYSDPICFGSQKTVDTLVDDLAHTMGVDRAALYVGAAAKGL
                     VVGYYQMTTTSAGVVDARLSNQDTLVPRMQDIHKVDLKDVAWVLVLEKEAVYRRLASSN
                     YHIRSAAGKGVLVTGKGYPDLSTRAFVRKLFDHSHQLTKKPQFYALVDGDPDGMAIMAT
                     YKYGSVAFAHENRNLNVPGLHWLGLRLAEVVAGADPLGDGTLLHLTKRDRKKAIDMLSK
                     NPVWEADGPEPEWRVELQRMLMLNVKAEMEILYDMEGGLTGWLDRKLVHLIQNSK"
     mRNA            complement(join(<7933..8412,8464..8535,8593..8673,
                     8723..8809,8865..8973,9032..9098,9146..9639))
                     /locus_tag="M747DRAFT_359727"
                     /product="meiotic recombination protein spo11"
     gene            complement(<7933..9639)
                     /locus_tag="M747DRAFT_359727"
     mRNA            complement(join(<10001..10076,10123..10340,10401..10434,
                     10479..10568,10616..10781,10844..10859,10905..11053,
                     11109..11127,11196..>11300))
                     /locus_tag="M747DRAFT_345872"
                     /product="terpenoid synthase"
     gene            complement(<10001..>11300)
                     /locus_tag="M747DRAFT_345872"
     CDS             complement(join(<10001..10076,10123..10340,10401..10434,
                     10479..10568,10616..10781,10844..10859,10905..11053,
                     11109..11127,11196..>11300))
                     /codon_start=1
                     /db_xref="InterPro:IPR008949"
                     /db_xref="InterPro:IPR034686"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Terpene_synth_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Terpene synthase/cyclase metal-binding domain
                     protein (Score: 182.9; E-value: 1.6e-55)"
                     /gene_kind="biosynthetic"
                     /locus_tag="M747DRAFT_345872"
                     /note="EggNog:ENOG41"
                     /product="terpenoid synthase"
                     /protein_id="ncbi_M747DRAFT_345872-T1"
                     /sec_met_domain="Terpene_synth_C (E-value: 5.8e-16,
                     bitscore: 51.4, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MARSIHKTDFGYFLAIMAPNAERDQLRTMCDWGNWVFPFDDAFDN
                     GELKVDLDGVKRMMDELLAVMTNEGVFRPRAPIVIAFKSIWDRLSESNCSAGTRRRFAN
                     SMRDYSEACIQQVIMQSKFQGSETLSVEEFIVMRRGSIATTPLYALFEYANGLNIPDEV
                     FESSSIKKLERVSTEVTVIQNDIVSYRKEQILDESSNLIKIYLRQGFSVQAAFDEAGKL
                     LAACYRDWYLTLADLPSWGEDVDAQVQTYIDGLQNTVLADIHWSFRAERYWKSNAEIQK
                     DRTIEVRVK"
     mRNA            join(13585..14161,14229..14647,14704..15495)
                     /locus_tag="M747DRAFT_299168"
                     /product="transcription initiation factor TFIID complex
                     subunit"
     gene            13585..15495
                     /locus_tag="M747DRAFT_299168"
     CDS             join(13792..14161,14229..14647,14704..15258)
                     /codon_start=1
                     /db_xref="InterPro:IPR004823"
                     /db_xref="InterPro:IPR009072"
                     /db_xref="InterPro:IPR011442"
                     /db_xref="InterPro:IPR016024"
                     /db_xref="PFAM:PF02969"
                     /db_xref="PFAM:PF07571"
                     /locus_tag="M747DRAFT_299168"
                     /note="BUSCO:EOG09260THV; GO_function: GO:0046982 - protein
                     heterodimerization activity [Evidence IEA]; GO_process:
                     GO:0006352 - DNA-templated transcription, initiation
                     [Evidence IEA]; GO_process: GO:0006367 - transcription
                     initiation from RNA polymerase II promoter [Evidence IEA]"
                     /product="transcription initiation factor TFIID complex
                     subunit"
                     /protein_id="ncbi_M747DRAFT_299168-T1"
                     /transl_table=1
                     /translation="MSVWNPDNIRDVAESVGVVNLSNDVTENLARDVEYRIAQVLEEAL
                     KFMRHSRRTLLTTQDVAQALRVLDVEPLYGYESTRPLRFGEASLGPGQPLFYVEDEEVD
                     FEKLINAPLPRVPREISFTAHWLAVEGVQPSIPQNPTAADSRNMELMSKGPNASSTLAA
                     MSGGGNVSVKPLVKHVLSKELQLYFEKVCNAFLDESSEEYRTSGYASLREDPGLHQLVP
                     YFVQFISEKVTHGLKDVFVLTQVMHMAEALVQNKSLYVDPYIASLVPPILTCLIGRQLG
                     GSAELTEQFALRDLAASLLGLIAKKYSNSSHTLKPRLARSCLKTFLDPSKPFGAHYGAV
                     IGLHAVGGAEAVRVLIMPNLPTYGNLLKDGMAEESPRRPEAERVLSVLLGVLNTLREGR
                     MALANGHGGMVTDGLRDRLSQKVGEFLAAKISDAGEVDLAHAIVESSS"
     mRNA            join(<16912..17032,17089..>18467)
                     /locus_tag="M747DRAFT_246471"
                     /product="S-adenosylmethionine decarboxylase"
     gene            <16912..>18467
                     /locus_tag="M747DRAFT_246471"
     CDS             join(<16912..17032,17089..>18467)
                     /codon_start=1
                     /db_xref="InterPro:IPR001985"
                     /db_xref="InterPro:IPR016067"
                     /db_xref="InterPro:IPR018166"
                     /db_xref="PFAM:PF01536"
                     /locus_tag="M747DRAFT_246471"
                     /note="BUSCO:EOG09263LNF; GO_function: GO:0004014 -
                     adenosylmethionine decarboxylase activity [Evidence IEA];
                     GO_process: GO:0008295 - spermidine biosynthetic process
                     [Evidence IEA]; GO_process: GO:0006597 - spermine
                     biosynthetic process [Evidence IEA]"
                     /product="S-adenosylmethionine decarboxylase"
                     /protein_id="ncbi_M747DRAFT_246471-T1"
                     /transl_table=1
                     /translation="MVYIGIPQHYTTSPSSFMGTPSLTINHEATQDLDSTNAFEGPEKL
                     LEVWFAPSAQELGSAGPAGLKAVPEEIWKDMLDLVNCQVLSIVSSEDVDAYLLSESSMF
                     VWPHKLILKTCGTTTLLSGLPRILEVAALFGGFPRATAPASRGISVAAAPYRVFYSRKN
                     FLFPDRQRGPHRSWRDEVRTMDKLFLNGSAYMIGKMNGEHWYLYLTEPNTLLTPPTSPR
                     VESEDPVTETKVLQVPAAGAYQTREDQDETLEVLMTDLDEENAKQFYLDHATAVAEKRY
                     CNFEADNDDHVDVFSNNSDMDDVSSNGSRVLPPELTTEGHALGTVVSESCGLSDVYPKS
                     KFPESRIDAYLFTPCGFSANGVIPTPDQNTGTHYFTVHVTPEPHCSYASFETNVPHSQN
                     GQTTQEIIQQVVNIFKPGRFTVTLFEAKPETTTADGELDHIKEVKYIERQAARRTKMEN
                     VAGYRRVDRIVHDLDGYDLVFRYYERLDWKGGAPRLGEERV"
     mRNA            join(18881..19587,19659..20327)
                     /locus_tag="M747DRAFT_267627"
                     /product="transcription initiation factor TFIID subunit
                     beta"
     gene            18881..20327
                     /locus_tag="M747DRAFT_267627"
     CDS             join(19097..19587,19659..20202)
                     /codon_start=1
                     /db_xref="InterPro:IPR006809"
                     /db_xref="InterPro:IPR009072"
                     /db_xref="PFAM:PF04719"
                     /locus_tag="M747DRAFT_267627"
                     /note="BUSCO:EOG09264VRO; GO_component: GO:0005634 -
                     nucleus [Evidence IEA]; GO_function: GO:0046982 - protein
                     heterodimerization activity [Evidence IEA]; GO_process:
                     GO:0006367 - transcription initiation from RNA polymerase
                     II promoter [Evidence IEA]"
                     /product="transcription initiation factor TFIID subunit
                     beta"
                     /protein_id="ncbi_M747DRAFT_267627-T1"
                     /transl_table=1
                     /translation="MSSPPPPSSNPLKRPSISSASSQPLGSHPKRPRMHPLRQTSFPNT
                     IDADTRTYSDAGSVTGSFTGSLGGTSADGVFLTKGKKRGRKSKAEKEREREEGSLRAGM
                     DRLGSVDVDGASVRGGASGGAGGGGGGEDADEDEDFDDEGELLGREEGTTDTEAEKKNM
                     ALLVDAFNPIQSERYDLFKRAKLRKETLRRIVNHALSQSVPASVVTTINGFTKVFAGEI
                     IEKARTVQAEWAIAHDQAALAAIEAEQATTTTTTTTTPGGIKQEPMERGPMSTPMGKKD
                     VKLPPNPHRGQLLPSHLREALRRYKRDGEGGGVGFSGLSMGNLGVRGSVTWSAGSVGGR
                     RIFR"
ORIGIN
        1 ggggccccag ccaacagaga cagcacctga gaaggatcca gtcacggaat ctccacctcg
       61 agttcaaaat ccagctcagc cttcagtcgg tcacgataac gtacctatcg cggtcaacca
      121 agttcttgcc ccttggagtg gtccaaagcg cgcgtactat cctgcaacgt gctttggcaa
      181 gccatttggc acatcgcagt cgcggtatct tgtcaaattc gaagatagtg caccgcttga
      241 gattcctact ggagcggtga aacgacttga gctgcgtatc ggtgatggtg tgaaggtgga
      301 catgcgcgat gttcccaagg tgacacatat tatctctggg tttgccgaca agctcagttt
      361 gagtgatatc gaacagggag ctgcgaacgg actgattcct atgaccgatg tgtatggata
      421 ttcatccgtt atcctgacac cgaagcagcg caagagtctc cctggcccag ggctagcagt
      481 cacagaaaac aggattactg ttcctatatc ccgaatctac ctagatacca tcctttggaa
      541 tcaattgaaa gaccgggcat tcagctatga ttccgagcct tcattttccc agaacggacc
      601 ccaaacgcca gccgacaggc actccacgcc catgtcccct ggtgctcgac tctcgcgcag
      661 cttccgtttt tccactggtc tatttgctgg tatggtattt gcggtatcat acggagacaa
      721 caacgaggcc aaatcacgta tcacaaggat gataatggag aatgacggcc ggattctaga
      781 ggacgggttc aacgagttgt tcgaactccc tcccagtgca ccagttgcta cacctaccaa
      841 gtcttcagct tcagtcccta gtacccaaaa cggccatctc cggctgacca gtggtgccgc
      901 agacgtgggc ttcgcctgtc taatagccga taaacattcc cgtcggtcga agtacatgca
      961 agccctggct ctcaatctcc cctgtctctc agaccgctgg atcgaggact gcgttgcccg
     1021 aggacaaatc ctcgattggg aaatatatct ccttccagcc ggggagtcca tctaccttaa
     1081 cggcgcaacc aagtccagat ttttaacccc ataccctgcc acagaggccc gactgtccga
     1141 gaccattgct ggacggccaa atctcctgaa cggacagtca gttcttcttg tcacgggacg
     1201 cagtgggcga gcagatgagg agaaacgcaa ggcgtacctc ttcttgacat acgcgttggg
     1261 tgcttctcgt attgagcgcg tgcctgatct caagtctgcg cgtgcgatcc tgagtgcgac
     1321 gcagacggat tgcaccagct ggaactggat ctatgtcgat gatgatgatc gagcgttttc
     1381 cgccaaagcc atggcactag gaagttcatc gtcgaccgcc ggttcgcgga agcgtaagcg
     1441 gtcgaagctg atggaatccg ttgacagcaa tgagctagga gtgaacagta atgtcaagat
     1501 tgtcggcaat gagtttctct gtcaaagctt gatcttggga aagttgtttg accagtaata
     1561 aattggatct agtggggtta acatcttcga cgatcatcta tgatgaatgt atggggtctg
     1621 gagtatctgc ttgtttttca tgcttgctgc tttgatcaat cagtgtgttt gcgagactga
     1681 tactgatagc aatataccct ggagtctgct actctgttaa aatctcagtt attgttctaa
     1741 ttaagaagaa aaggagtagt aattgcagcc cattcacaga cgtcttatga tacatacata
     1801 catataggta gacagacaca aaagaaaccc tagaaccaga actaatatat cacacacacg
     1861 cagtcaaatc tctctctgat ataatctcca tcacatcatc tattttccac ccttcttctt
     1921 agcgcccttc ttcttgttct tcaagctctt catctgtgcc atccgttcag ccttagccgt
     1981 cctctttctc catgccaacc aacggttctt gcggttatac ggcttggccg taataccagc
     2041 cttctccgca gcccgaccaa tactccagtt agcctcacgg tacatataac ccggacgcaa
     2101 ctgaaccgca gcctgagcag cctcaacctt agtagcactg ccaacctgcg tcccttcctc
     2161 tccaatctta gccaccaaat cgccctgctt ggcggccaac tcctcctcag gctcaaaccg
     2221 aaccgccacg cggttcaact tccgcctagt aggcgcattc ttcggtgtcg gcaacttgcc
     2281 ctccttctca aacacaactc caatgtactt ccgatccgga tggcgctcag ggtccaggta
     2341 gtaccgtaca tacccagcct cagcagcgta gatggtatgg tcgcggccca tggcgcagtt
     2401 ctcgccaggg aaccatttcg tgcctcgttg ccggaagatg atgcatcccg gcacgacgta
     2461 ttcgcctgct gtgcgtttcg cgccgagacg cttgccagcc ggatcgcggg agtgacggtt
     2521 cgcggtacct tgagaggcgt gggaggcgtg tcggacttgg aggaattggt gtaatgttgg
     2581 agatgctagc ggggtgagct tggtttgtgt tatgctggtt gcggagagga tggaggaggt
     2641 gttgcggagg agcgaggagg tgttgcggat gctggtggta gcggcggtgg gggttctggt
     2701 gagtcccctt tctagagccc ggaggggcgc tagaagacga ggttggaaca ttgtgtgggt
     2761 tggggaatga tgttcaatgg gattgaactg ggggagggag atggctcgct ctattccggg
     2821 gctgcttttt ttcgcggatc ggagatggac ttggcgggta aggtcacgtg ccggatgcgg
     2881 ccagatggcc ggtaagttat ctacaactat atacttctct gctggctttt atcgatgatt
     2941 tgatttgctt cgctttttga tttggatata ttgctcgctt gtttgtttag gcaccattcg
     3001 caatgttctc ctggattcgg ctcctcggag cccttcttct acttgcctcc gtggctcacg
     3061 cccagttcca gttctttgag catatgtttg gaggcggcgg cggcggtggt ggtcaccagg
     3121 gtcgtcagca ggcggcgcag aatgttccaa gtgatagctc gcggtatcag agtcaatggg
     3181 actcaggtaa gtactgtata tttcgattga gctatgcgtg cagcgctgat ccgcacagcc
     3241 cattgcgata aatacctctg ccctggcacg ctcgcatgcg tccatttccc gcatcattgc
     3301 ccgtgtccgc atcccgatgt cgaagagaag gttgagcttg gagaaggaag tgccgtttgt
     3361 gtgtcaaagg gaggatacaa ggagggtgag gcggcgcgga agattgagct ggcgcgcaag
     3421 ggtcttttgt gattgaaatg tctgaaagtg gttacatgtc gcttttcagc tgaattgggg
     3481 gttattggtg ttggtgtttg tgcgtattgg ttctgaatat gtcttatgga ttctactgtt
     3541 caggatgtca cttctgaggc ctgcgcgttg atctgcgtcc tggctgagtg actcttgcag
     3601 cattatcgct atgttactgt cgaagggctc ttggattatt acataggcag ctgctctctt
     3661 gattggagca gtcagcaact tgaaatccgg gatatcgcct tgcgctcggg ttgttgatca
     3721 gagagaccaa tccgcaccta atacgtacat tttaggcgtc tgcgcttact ttacggcgtc
     3781 attttaaaaa ttataatatg cattccaatg tcaatcttat cagcactgtg tgttgtaagc
     3841 ggttgtatcg caatcagtct taggcagact atcagcacag ctgtggagta ggttagtcca
     3901 cgtaggcaga gctggaaaag acaatctgga acgacatggg agaggtcaat tcttcaattg
     3961 actacaatca tctgtctaaa taagggtgtc cctcgatact actgaaactg ctgttccgtg
     4021 tggattatca tgacttatgg tcataagtag tacttgaatc attgtgtgat cagttggagc
     4081 agatcacttc aagggcagaa cgtgttaaat aaatatattt agtatcaatc gagtccagat
     4141 atccagtatt aaaactgagc cggttggaga ttgttcctat acactggagt tagagcttct
     4201 tatacacttg tttgtaggta ttcccaacac agatgagaaa gtactgtaaa ataaataccc
     4261 tgagttatct cgcaatcagt ttgcggggtg gatgaaggca aagagggcag cggatggatg
     4321 atcagcgtct tatcgccgtt aactccgccc gctcccgcaa cttcgtcatc gcgggaatct
     4381 tccatctttc tcttccatct tcagcttatt caactctact tctcggtgct acagtcacct
     4441 tacatacctt tgtctaattt cgcatcatac atttttaccg actggccccc aacactggaa
     4501 tgtggagtgc gctccgaaca ccaccggcgc agtgccttcg agctcccggt cgagctctcg
     4561 ccagctcact tcgcggccga cccaaccccc gaggcccccg aaactccata cgcaggccag
     4621 agcccatcag aagagacgtc ccagcgtcgc gagcgcctga acccagcaat acagagacat
     4681 ctcccgaaaa tcccacgcct caatatgacc cctcccagaa caccctactc gccccagttc
     4741 acatccccga agaccctcat ggcgtgataa aagagacgca cccggcgacg ggtatcctcg
     4801 ccaactcagg tctggtggtg cagcggcagt tggagctcat gaatgtgatg attggattcg
     4861 aacaagccaa caaatacgtc attatggatg ccaacggcaa ccatattggc tatatggcgg
     4921 agcaggagaa aggcatggtg aacatgatgg cgcgacaatc gttccgaacg catcgaagct
     4981 tcgtgacgca tgtgtttgac aagcatgaga atgaagtgct tcgggtaggt atcgatctgc
     5041 cagttacttg tggatgatgc tgactgcgta gttccaccgt ccgttctcgt ggatcaactc
     5101 ccgtatccgc gtatatgatc ctctcgacct ggcaaagggt gcctattcct cgtccactgc
     5161 actacaggca acctcagccg gatctctggt ccagcctaca ggggactcga atgctcgggt
     5221 ttcatccttg ggcttggatg aaatacgggt tatcggagag gctcagcaac aatgggctcc
     5281 actacggcgg aaatacaacc tcttcacgta tcaccactcg ccaaatccag cgacagagat
     5341 gaaaacagag aagctaccgc ttaaccagat ggatttgtct aataagcagc aaatgcagct
     5401 ggtccaatca tctcagagtg gccaagaaac gggcgaatat caccaattcg cctacgtgga
     5461 cgagcctttc ttgtcgtggg attttggtct acgctcggct gacaaacagc tgatcggctc
     5521 tgtgaatcgc aactttgccg ggtttgcccg ggaaatcttc acggatacgg gtgtctatgc
     5581 tctgcgaatg gactctgctt ctcccagcga agagttcctc gacaagaacc gtgcggctac
     5641 tgggatgaca ttcgaccagc gtgccgtgat gctggcaacc gctgtgagca ttgactttga
     5701 ctactttagt cgccatagca actcgggtgg atttggtttc atgcctctct ggatccctgg
     5761 atttggtggt gaggcagctg ctgggggtgc tgccgggggc gcagcagccg gtgaagcagg
     5821 tgccgtgggg gaagcggccg cgggaactct tggtcgggct ggggcagccg gtggaatggc
     5881 tgatggcgct gcagcaggtg cagcaggtgc gggcgcaatg gctggctacg aagccatgtc
     5941 ccgtgggatg ggaggcagcc agcctgctcc cgatcagcaa gcggcacctg tagaccaaca
     6001 gccaccgacg ccaggtcaaa cgggtccgta tggagatgtc tggggggaag agtccgagaa
     6061 cccatgggga aaggagcctg agaacacatg gggccaggaa gaggatccgt gggcagatga
     6121 agccgacgag ggcgagggag gcgatgattt cgattggttt taagcggctg ataactacaa
     6181 acaggcagta agatcaggat ggttgacatt gtgagacggt cagacatata ctatcccccc
     6241 attcatgcag ggataacgac gacagagctc atgtaatcgg gggcactgag aatcaccgta
     6301 acggcttcaa tgacatggcc tgcggcatac tcgacatgat ctgaccgagt agacatcgat
     6361 gtcattcata ctcggccctg cttgaagtgc aaagcggttt atgcagctga ctgacgatga
     6421 ttagcccgat gtaccataac gacaaaaaaa tctccaaata actgtataat atcacgcgaa
     6481 aaatgaaaca atgctagcca gaaataaact caagatcatt ctccttccat actgatgaaa
     6541 gcggcgataa gcatcattgc agcctcaggc acccaacaca tcccaccggc tcaaccatcg
     6601 atgaatggaa cctcaatcac tcaatcattc attggctttc agagtggcaa accttgattt
     6661 ctcctccaat tcaattccaa cccactcacc ttccccagta aaccgacctc taaaaagttt
     6721 ttcttagtcc tatctcctca acgccacccc aggtacataa ccaccacccc tattaagtac
     6781 ccccggtgtc ctcaccctct ccggtccgat ctccgcactc tcctctcccc tctttatcta
     6841 atcgccagat agacagccag accgccacca ccaccagcac caaaaaccca ctacctgctt
     6901 ccctcccacg acgccggaga aattattaag ccaataatta aaatcaatac ttctctcaaa
     6961 gagaaaggaa ggcagtgatc aatcaaaatg tcctccgtcg cccagaaacg cctcttccac
     7021 gaatacaaaa acctctccac caaccccccc gagggcatca ccgccggccc cgtcaccgaa
     7081 gatgacatgt tccactggga agcactaatc caggggcctg aaggtacgcc cttcgagggc
     7141 ggcgtgttcg cggccgagtt gaagttccct aaagattatc cgcttagtcc gcctacaatg
     7201 aagtttgtgg gtggtggggt ttggcatcct aatggtaaat aactccttct tttccctttc
     7261 tttctctatc tggatctttc ttgtcttcta gttttttttc tggtgatgct tggttgagct
     7321 tatgctaacg tgttttggac atacgtatag tataccccaa cggaaccgtg tgtatttcca
     7381 tcctccaccc ccccggtgac gaccccaacc attacgaaca tgcttcggag cggtggtcgc
     7441 cgatccagag cgtggagaag attcttatct ccgttatgag tatgttggcg gagccgaatg
     7501 atgagtctcc ggcgaatgtg gaggctgcga agatgtggag ggagcggagg ggggagtatg
     7561 agcggaaggt gagggatgag gttaggaagg gattggggct gtgaaaccct ctcttcttta
     7621 atatgagttg aatggtgaat gggaggggtt tggccgtata taagtaaccg gttgctgggc
     7681 tggttgctca ctgtctgtct atactctgtg tcgtggagga aattgtggca tagcttggat
     7741 ggatgcattg gttgcttggg ttggcgttgt ggtgcgttcg ttctttctct ctctttcttt
     7801 catctttata tatattctat ttgacgccca ctactggggt agatgcatgg tcaggaatgc
     7861 atagatgctt tgttcagtat atatcattat cttttgttgt gataatggta cgaagtcatg
     7921 aatacgtcct acctacttac tgttttgtat gagatggacc agcttcctat ctagccatcc
     7981 tgtcaagcca ccctccatgt catacaggat ctccatctct gccttgacat tcagcatgag
     8041 cattcgctgc agctcgaccc gccattccgg ctccggtcca tcagcctccc agacaggatt
     8101 tttagacagc atatcgatgg ccttcttcct atcccgcttc gtaagatgga gtagcgtgcc
     8161 atcgcctagt ggatcagctc ctgcaaccac ctccgctagt ctcaaaccta gccagtggag
     8221 accgggcaca ttcaagttcc ggttttcgtg ggcaaaagcc acagagccat acttgtatgt
     8281 ggccataatg gccatgccgt cggggtcacc gtccactaag gcgtagaatt gcggtttctt
     8341 ggtgagttgg tggctgtggt cgaagagttt acggacgaat gcccgagtac tgagatcagg
     8401 atatcctttt ccctggaatg gttggtatgt ctcttagaat gtaatagggg tatcagcact
     8461 tacagtgacg aggacgccct tgcctgctgc agatctgatg tggtagttgc tgcttgcgag
     8521 tcgacggtat acggcctgag ggtgtcagtt cactccagct tgatatataa agtttttgat
     8581 ggcagcaggg acctccttct ctagaaccag tacccaggca acatctttaa ggtcgacttt
     8641 gtggatgtct tgcattctag gtactagagt atcctgcgaa catcagtcca tgctgtgtgc
     8701 agtagtgatg actgcaacgg acctggtttg ataaccgcgc gtccactact cccgcgcttg
     8761 tggtggtcat ctgatagtat cccacgacaa gtccttttgc tgctgccccc tgtgttgcag
     8821 gatacttagc agtctggaag taggtactgt tgaggcccac gaaccacata taatgcagca
     8881 cgatccaccc ccattgtgtg tgccaggtca tcaacgagtg tatcgacggt tttctgggag
     8941 ccgaagcaga taggatcact gtagtatatg tctctatgtg aaatttagtg ttcgaaagtg
     9001 ttagagtaca ctggtggtcc gtgttgttta cctcttagag accaccaacc ccgcctgaac
     9061 tgcctctgcg atggccgcga ggactcgaag agcggcagct gtgtcttcat tagcagagta
     9121 tctgaatggt gacaacatat cgtactgaat ttcaatgctt cgttcatatc gccgccgggc
     9181 catctgtagg tggtgtatgt ctgtatctcc gacgtctcca gggccaatgt acgtgggtta
     9241 atgaatagtg aggcaaactt tttacctctc tgtttgaggg taatagagag gtggccttca
     9301 cggaaggata cttcatccag gattgctgct agcgtttcct gaatgtagct ttggactggt
     9361 gtttggggaa ttgtagcgat gattgttagt cgttcgaacg cctcggcttc catgccatct
     9421 aaatgtgatg cttccattgt ttctaggatc aacaagatgg gttaggagag gatgacctgt
     9481 aggggtggga cggcgatggt ccggaggcga aaggtggaaa tagtccaaga ggggttgcga
     9541 gtatgcgacc caacatatat tgtacctaat cacgttacaa ctagtgagat gagttcttct
     9601 tgtacaatat aaaatggcaa gtaaatggcc ggaaccaaca aaaatcacta cataatgatc
     9661 ttgactggcc agtgttcaaa gtatagcaag ccggtggcac gtagtcacat gcacagagtt
     9721 agctaaaccg gtttcctgga atatcgctca tatcttcata caagaaatga agtacatcct
     9781 gcttagggag ccgggggtgg aagatgacta ggctgcgacc agagttatta ttcaagtaag
     9841 ctaattatac tgattcatgt ttaaacaagc atcagcaatg cgaatgctca taaagagcac
     9901 tactaacatg tttcactgcc aagtgccata agacttaagt catgccccct tcagtctgaa
     9961 tcagacaacc taatacattc caagcacagt caagacatcc tcatttcact cgcacctcaa
    10021 tcgttctatc cttctgtatt tccgcatttg atttccaata acgttccgct cggaaactac
    10081 atcgccatca gacatcgtag cgaagttgag attagctctt acctccagtg gatatcagcc
    10141 agaacagtat tttggaggcc atcaatatac gtctgaacct gtgcatcgac atcttcgccc
    10201 cagctgggta aatcagctag tgtcaaatac caatcacgat agcatgcagc cagtagcttt
    10261 ccagcttcgt cgaaagcagc ttgaactgag aagccttgcc ggagatatat tttgatcaag
    10321 ttgctgcttt catcgaggat ctggaaggga aggttagtca ttctgtacct atagctggcg
    10381 gaccataaat atgcacatac ttgctccttc cgataggaaa cgatgtcatt ttggctgtgg
    10441 agtcagtagc cggcttctac aacggacaag gttcttacat gaccgtcact tcagtgctga
    10501 ctctttccag ctttttgatg gatgaactct caaacacttc atctggaatg ttcaatccat
    10561 tggcatatct ggatcgtcag cacgtttgat ccttccaggg agggaaaagg cctactcaaa
    10621 tagcgcatat agaggcgtcg tcgcaatact tccacgtctc attacgataa attcttcgac
    10681 tgacagtgtt tcactgcctt ggaatttgga ttgcatgatg acctgctgaa tacacgcttc
    10741 ggaatagtct cgcattgaat tagcaaaccg acgacgggtt cctgtgtgtc gttgatccca
    10801 tcaacttcat attcagatca attgaggctg acaatgtgat taccggcaga gcagttcgac
    10861 tgaaatatta gcgaggatca cagtctcatc gacataatac tcacctcgga tagtctatcc
    10921 cagatggact tgaacgcaat aacaatagga gctctcggtc taaagactcc ttcgtttgtc
    10981 atgacggcca aaagctcgtc catcattctt ttcacaccat ccagatctac tttcaactct
    11041 ccattgtcga aagctgttga catcgcatcg tgagaacagg gaagtgcgat tgaacaggaa
    11101 aacactacca tcatcaaaag gaaaaacctt gattcagatt agtatacaca gtacacctaa
    11161 agagaatcaa cacagggaga tcaacgcgga cgtacccagt ttccccaatc acacatcgtt
    11221 cgcaactgat ctcgctctgc attaggggcc ataatggcca agaagtaccc aaagtcagtc
    11281 ttgtgaatag atcgtgccat attttcatca aatttgcagg cccttcaaag ttttagatga
    11341 aggtactaga gtgaagaaag ggtcacttat acttgatcag ccactgctcc gactcctccc
    11401 tgatagcttc ataatgccga ttcactggag cctttctcgc aacgaagctt acaaataacg
    11461 gaggcaattt cacctcgacg atagtgtcag cgtcccaacc catcttcctg gctcgtaaat
    11521 gggtatatca gtttatgctg gataagatgg acaagtaggg tgtcggctga atacttataa
    11581 gccaactcgt cgatggctcc tatgacgttt cacaatacta aatatgaatg gatgcatttc
    11641 tcgacagcta cagtgatatc cccttcggac tgccttcata agagtgatgt caccgtctaa
    11701 ctgaatcatt ccccctcatt tcctccctct gtggtcaaca gcagctcatc aagatcaatc
    11761 gaagcttgct cgggactcta tgcaaggatc tgcagggcat taccaccttt gctgattcga
    11821 acaggaatgc tgtatctctg ccctatcgca attgaatatg catcacagtt accccacata
    11881 aggcaagcca tactccttcc caatgcgttt gagttatgat gaaacgtact ctggtcgagt
    11941 gcgagaagat cgttagtggc atctattggt ccactggtcc actcgtggca aacatgtcac
    12001 tggcactacc gcttcctttt agagcaatga tgtgaggtta ttcagcaact ggaaagacaa
    12061 atgaaaacat cttcctatat gagtgggctg gcatagttca ctgatgacac taacgccgac
    12121 ccttacgaac catttcaaag tagccccagt tgaccgactt gagctagtgt aaccgcatcg
    12181 ctgtccgttc cagaatacaa acctaaattc tgccagacct cgatgtccgg aatgaacctc
    12241 gctattaccg acatggacga agccactagt aggcaaacga aaaagaatat tgtcaaccaa
    12301 gattaataaa gcatgcttcg tcaagacaaa tgtctcgagc tccaatagta ccaggtgcgc
    12361 agtttgttga ggaaacaatc gaggacttcg gccaacgcag gcgtgagtgg agattgcatg
    12421 ccaatatttg ggttggacga gactgaatgt ggtcaagtga ttgataccaa cctgtccagc
    12481 atcgctcact tccttaagtg gacaaatggt caagcaaggt cacggagctt cccttatcaa
    12541 tgtctcctcc agcgggattc taaagacggt gcctaccatt tctgcctatt gtgcttccag
    12601 gcacgatgtg gcacgactgg ataaggttgc gggtagtgta ttgtggctta tatctgggac
    12661 ttctttgtat gttacaggag tcatgatttc tgtcaatgca gtgtaatcct tgataggagc
    12721 ccgaattata cgtagtgatg taatgaaatc tcagtgctgc cgagcacgga ttgaattatg
    12781 ctccttgttt cttgcacata ttcctggtag ttggtatttt gtaagagctt ctgaacttag
    12841 aaacttgcag atgaaatcct acaggttgat attgaaagtt acccacacta tagcccttaa
    12901 atttgtgact ttgtaggttc gtctttctca ggcatctgga taattccatc ggacaaagga
    12961 gaactgttgt gcgaccctaa ttatcgtgca ccacgctcaa cataatcatt cttgagggcg
    13021 tacataggaa tgtgggggca atgcgatctt ccatagcaat cttaaacggt ggttgtgcat
    13081 tatgactgtg ttacccatgg gatatagtaa ctgacagccg tatcttaagc cttgcttact
    13141 ttgagttgta tatttggctt gaaaaatgtt ttcaacaagt gccagatcga cctatgccac
    13201 atgggcgaga gggcaatgga gtgaagtgat catggattgg caagaaatgc gaaaaatatc
    13261 catgtattgg tgaaggggtc aactgcatcc tcttgtggta ggatagggca ttttagacct
    13321 agcaaattag acgtatgaac gcttcttttt agctgttctc tatcttatgc ttcattcaac
    13381 aaactaaaaa acttggtact acaaatatgg tataattgct ttcacctcgt atgatatttg
    13441 atatgtttgt aaacactata tcctgattca agtttgcgat tcctacacgg agatagttga
    13501 agatgcacgt gtggatgccc agcggcaggt tttctccgcc ttctgcctcc gaagctctct
    13561 ccgttcccgc gtcgcattta tctgctatcg ttcatttcga cattgcacct ctgggcctcc
    13621 cagaatgatt ttcggccttc ccggataata aatttgatgg tcatctactc gcctcaaatt
    13681 gcaggaaata cctggcccac tcgttgacga accgacgacg ttacaccctc ccgcccaccc
    13741 gatacctcct acctccgttc ttttacctcc acctcaacac tcacgcccac catgtccgtt
    13801 tggaaccccg ataatattcg cgatgttgcc gagtcggtcg gtgtcgtgaa cctcagcaat
    13861 gatgtcactg agaaccttgc ccgcgacgtc gagtaccgca tcgcgcaggt cctggaagag
    13921 gccctcaaat tcatgcgcca cagtcgacgc acgctactca cgacacaaga tgtcgcgcag
    13981 gcgctgcgcg tgctggatgt ggagccactg tacggatacg agtctacaag gcctttgcgg
    14041 ttcggagagg cgtcactggg ccctggtcag ccgttgttct acgtggagga tgaagaagtg
    14101 gactttgaga agttgataaa tgcgccgttg cccagggttc ctcgcgagat ctctttcaca
    14161 ggtaaacttg gccctgctgc tctatggaaa tatttacaat gaagtgttgg catgctgact
    14221 ccattaagcc cattggttgg cggttgaagg tgtacaaccg tccatccctc agaatcccac
    14281 ggcggccgac tcgagaaaca tggaactgat gtccaaggga cccaacgcaa gctctacatt
    14341 ggcggccatg agtggaggag gaaatgtctc cgtcaagcct ctggtgaagc atgtgctttc
    14401 caaggagctc cagctatact tcgagaaggt ctgcaacgcc ttcctggacg agtccagtga
    14461 ggaatacagg acgtcgggtt atgccagtct ccgagaagac cccggactac accagctggt
    14521 gccatatttc gtgcaattca tttcggagaa ggtgacgcat gggctgaagg acgtctttgt
    14581 cctgacgcag gtgatgcaca tggccgaggc tctggtacag aacaagtctc tctacgtgga
    14641 cccatatgtg agtcatgatt gtcacatgaa caacgcagat tacattccac tgactcctga
    14701 tagatcgcct cacttgttcc acctattctg acgtgcctga tcggtcgaca actcgggggc
    14761 agtgctgaac tgacggagca atttgccctg cgcgaccttg ccgcatcgct tctgggcctc
    14821 atcgccaaga aatattccaa ttcgtcgcac accctcaagc cacgactggc ccggtcgtgc
    14881 ctgaagacgt tcctggaccc gtccaaaccc tttggggcgc actatggcgc ggtgatcgga
    14941 ctacatgcgg ttggcggtgc agaggcggtg cgggtgctga tcatgcctaa tctgccgacg
    15001 tacggcaacc tgctcaagga tggcatggcg gaggagagtc cacgccggcc ggaggcagag
    15061 cgggtgctta gcgtgctgct gggggtgctg aacacgctac gggagggccg gatggcactg
    15121 gccaacggtc atggcgggat ggtgacggat ggtcttcgag atcggctgag tcagaaagtg
    15181 ggtgagttcc tggccgcgaa gattagtgac gcgggggaag ttgacctcgc tcatgccatt
    15241 gtggagtcgt cctcctgatt ctgctgcatt tctctctcta caacttgaag tagcatctca
    15301 ttctgtatct actttggatg tacatcttta ggggcagcgg gtgaagagcc atgcgtgctt
    15361 tctttcattt ttcttagttt gagtgtttgt tgctgggcat ggacagaatt cggcgtttgg
    15421 ggcaaagggt gttttagaag gagggaatca ggactattct tgaatgctag ctagcgaatt
    15481 gtacctctgc ataatatctt gatgctttgt tgacttcaac ctgctcattg tgctgggagg
    15541 gaatttagta gtggtggaag ttgtgagacc gatttcccga tgggagggag acacgacgtc
    15601 accctccctt ttgagaagaa gtcgaccctt gtactaccgc ctgcctggtt gggcacgaaa
    15661 tgtcgggctt tttccgtttg gcagggaaaa tccgatcggc tcattcctta ttcctggcct
    15721 tcttttccgg ccattcgaaa ggagcatctc atcatcaatt catccatcgc gccctcctgc
    15781 ctctccaggg atcgtgtgtg gttggactaa aattcttata attgcccagg taagttatat
    15841 gttcctgcat cttccccctc atcccatccc attcctcttg gtgtctccga ttctgaaccg
    15901 ttttcccgcc ttctctcaga ttctgcgcgt ttgattccca aaagagccca acccagattg
    15961 gcctctttcc tttgcccgcc ccacgaactt ttttcgggcc cacagatcac ggacagcaat
    16021 aataatcgct caaccgtcgc ccgtcaataa ctacttcttt cttcccttcc cccccccacg
    16081 tccgcgtgcc ttttttgaaa tcttatttat ttccctctcc ttcctcctca ctcatccggt
    16141 ggaggttcta tcgctttggt tgtctttgag tcattgagtg atcaaagagc caaatcgctt
    16201 tgctgcattc cgctgcacac ttgccctacc cgttatcgtt gccgtcgaaa gtcgcctcgc
    16261 agatgttcag tgctgtggct tctcacgaca tcgtgctgtt ttaagctcgt cttctgtcct
    16321 gccttccatg aacccgaagg atctactacg gtacctgtct aagcctgcca agtatgtttg
    16381 ttgccgtttg tcttctttcc ttagtctctt cacttcgtct ccggtgggtc aaaagtttct
    16441 gtcatggcta acagatcgcg agtaggcccc gataacacgc ttgaacccca ccttttttct
    16501 ccagtcgcgc aaacctcact tttttctctc ccacatttca aaagcagata ctctcgtctg
    16561 ctagacccga tactttcgcc ggtatcggta tcttccagca cgagggtcac gaccagatag
    16621 tcaccattcc cttttccaga ggctttttcc tcctttccct ctctttccgc cctccctagc
    16681 agcccttcag gcttctaccg aaactacccc tctttggctg agtgccaatt accagaaaaa
    16741 cagattaagg gcctactctc tcagacggac atagcccccc tgttcgtctg ggcagcagat
    16801 agtgcttcct aggctctttg tctacggtcc acacatccag tcgcgcgcac ctgctatatc
    16861 gctgctccgt ccgctttacc gattaatttg ctgcattatc aatcggtcaa gatggtctac
    16921 attgggatcc cccagcacta cacgacgtcg ccgtcctctt tcatggggac cccgtccttg
    16981 acgatcaacc atgaggcaac ccaggatctt gattccacca acgccttcga aggtatgtgg
    17041 ctgtgatact aatggctcta tgttggaact atactgacgt gaatgaaggc cccgagaagc
    17101 ttctggaggt ttggtttgcc ccgtccgctc aggaactggg ttctgccggt cctgccggct
    17161 tgaaggctgt gcctgaagag atctggaagg acatgcttga cctcgtcaac tgccaagtgc
    17221 tctccatcgt ctcgtccgag gatgtcgacg cctatctctt gtccgagtcc agcatgttcg
    17281 tctggccgca caagctgatc ctgaagacct gtggtacgac gaccctgctg tcgggacttc
    17341 cgcgcattct cgaagttgcc gctttgtttg gtggcttccc tcgcgctacc gcacctgctt
    17401 cccgcggcat ctccgtcgct gcggccccgt accgtgtgtt ctacagccgc aagaacttcc
    17461 tcttccccga ccgtcagcgc ggtccccacc gcagctggag agacgaggtt cgcaccatgg
    17521 acaagctctt cctcaacggc agcgcctaca tgattggcaa gatgaacggc gagcactggt
    17581 acctctacct gactgagccc aacaccttgc tcactccccc gaccagccct cgcgtcgagt
    17641 cggaggatcc ggtgaccgag accaaggtgc ttcaagtgcc cgcagctggt gcctaccaga
    17701 ctcgcgaaga ccaggacgag actctggagg tgttgatgac cgacctggat gaggagaacg
    17761 ccaagcagtt ctacctcgac cacgctactg ctgttgccga gaagcgttac tgcaacttcg
    17821 aggccgacaa tgacgaccac gttgatgttt tcagcaacaa ctccgacatg gatgatgtgt
    17881 cgtccaacgg cagccgcgtc ttgccccctg agctgactac cgagggtcat gctttgggaa
    17941 cggtcgtgtc ggagtcgtgt ggtctttcgg acgtctatcc gaagtccaag ttccccgagt
    18001 ctcggatcga cgcctacctg tttaccccgt gcggattctc cgccaatggc gtcatcccca
    18061 cgcctgacca gaacaccgga acacactact tcacggtgca tgtgactccg gagcctcact
    18121 gctcgtatgc gtcgtttgag accaacgtgc cgcactcgca gaacggccag actacgcagg
    18181 agattattca gcaggtggtg aacatcttca agcctggacg cttcacggtg accttgttcg
    18241 aggctaagcc ggagactact accgccgacg gcgagttgga ccacatcaag gaggtcaagt
    18301 acattgagcg gcaggcagct cgtcgcacca agatggaaaa cgtggcagga tatcgtcggg
    18361 tggatcggat cgtgcatgac ttggacggat atgacctcgt gttccgctac tacgaacgtc
    18421 ttgactggaa agggggggcc cctcggctcg gagaagagcg cgtttgagag agcgaacacg
    18481 gtgtctgtcc atgcatgaga ggtgagaagg aagtgggaga atgatatcgt ttcttgactg
    18541 tttccaattt cgggttttgt cagctgttac tttcctatca tcgagcgatt gagctttgtt
    18601 cctttttgag caatgttagt atccaccttc gcttacggat ttgtggcatt gtggttattt
    18661 cgaacaaata ttatccgtcc tacggactgg tcaggtgcat tgatcgtaga aaacccgagt
    18721 agttgagcga cgaacgagtg aagtagaaat aagcagcggg cgggtgcagg agcgcgccgg
    18781 cggaaagtcg accactcggc agacttgccg gatggggcgc cgtaacaccg ataagccgcc
    18841 ttcctttggt tctttcatcc acactccgtc gcatcatctt cccccccagc agtctccata
    18901 acccagtcca tcacgtgtac actttctatc ctgaataact tgaacagctg agtctttatt
    18961 cgcgccttac cgagatttcg cagacagatc gagacacgac ttttcatccg cgctgcgagc
    19021 aagccttgtc ggctctcgac aaagcaacat caacatcaac atcacccatc acaccatttc
    19081 ttaacacaaa cacatcatgt cctcaccacc accaccgtcc tcaaaccccc tcaaacgccc
    19141 ctccatctcc tcggcctcct ctcaaccact cggcagccat cccaagcgac cgcgcatgca
    19201 ccccctccgc cagacctcct tcccgaacac catcgacgca gacacgcgca cctacagcga
    19261 tgccggcagc gtgacgggca gctttacagg cagtctgggc gggaccagcg cagatggggt
    19321 gttcctaacg aagggaaaga agcgcggcag gaagagtaaa gcggagaagg agcgcgagag
    19381 ggaagaaggg agtttgcggg cgggaatgga tcgactgggg tcggtggatg tggatggcgc
    19441 gtcagtgagg ggtggtgctt ctggcggtgc cggaggagga gggggaggag aagatgcaga
    19501 tgaggatgag gattttgatg atgaggggga gttgttgggg agggaagagg ggacgacgga
    19561 tacggaggcg gagaagaaga atatggcgta tgcatccctc cttttggacg actctatatc
    19621 tggcttgtgg gcgaagttgc taactggttc tggtgtaggt tgttggtgga tgcattcaat
    19681 cccatccagt cggagcgata tgacctgttc aaacgagcca aattacgaaa ggagacgcta
    19741 cgacgtattg tcaatcatgc gctgtcgcag tctgtgccgg ctagtgtggt tacaacgatt
    19801 aatggcttta cgaaggtgtt tgcgggtgag attattgaga aggctcgtac cgtgcaggcg
    19861 gagtgggcta tcgctcatga tcaggcggct ttggctgcaa ttgaagctga acaggcgacg
    19921 acaacaacaa cgacaaccac aacacctggg ggtattaagc aggagcccat ggaaaggggg
    19981 cccatgtcta cgcctatggg gaagaaggat gttaagctgc ctccgaatcc ccatcggggc
    20041 cagttgctgc cctcgcatct aagagaagcg ctgcggcggt ataagcggga tggagagggt
    20101 ggaggcgtag ggttctcggg tctgagtatg ggcaatctgg gggtgcgagg gtcggtgact
    20161 tggtcggcgg gtagtgttgg cggacggcgc atcttccggt aatggaatat ggatctggtt
    20221 atggtaaagc tgggagcgca gaggtgagcg tggatagcaa aatggtggct gaaatactga
    20281 gaaagaccac tgcagtaatg atagtatcat aataaatgat gatagacgga ttgtctatag
    20341 ttactgaaca ctgaacactc attctaatca tgattttact tctagcatgc atacccatca
    20401 ccttatatgc agtggcagat ctagagttgc atctcactga cctctactga gaatacatgc
    20461 aagaaagcgc ctatcccccc cttcccccta cacccacttc cctcgtttct actctcgata
    20521 aggtccatcc atccgttatg gttcccaccg caccatttgt ctcttggatt tcctacgctc
    20581 tactaccgta catgatatca gttgctgttg ttactatatc agctgataat gatgttaaca
    20641 tggtatgaat gtattattgt gtgtatatta taagcatata ataacaacca cgtccgaacc
    20701 caaatcaccg tttctatcct tcataaaccc accgcgacgc acaatttccg attcccccac
    20761 taccatcgtc atagacagtg ctctgtatca gtgtcataaa agtagtatgt cctcgcagtt
    20821 tactccaaca agcattcatc atcatcatcc ccctatcttt gcttttttcc attaccccgt
    20881 ttcgaagtat ccacgtagat aatgtccttt atatctcctc tgacttcttc ggttgctgca
    20941 atggttgcat gaatatctca gtttcagacg tagtatgata tagacagaca aatagacttc
    21001 tgatactagt agtaggtccc tccagtctac taccgtatat actcatgcaa gcaaagcaag
    21061 catttaccgt cgtaacttcc ttcatatctt actctgctct tcggttgttg atactagact
    21121 cgttgtatca accaacccac caccgatgtt acatcagtgg ttgcgcagca tatagaatca
    21181 tgctggtctc atcacctgtt cccttgtttc tgtttttttt tgtattgatg tagaatctaa
    21241 ggaacactga tacctggtgg aagtaaatgt tccttttcgt gtgtatgtat cccggtaggg
//
