LOCUS       KZ851953.1             22017 bp    DNA     linear   PLN 20-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   KZ851953
VERSION     KZ851953.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 07:38:58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 19469
            Orig. end    :: 41486
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22017
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[31291:>31486](-), [30879:31232](-),
                     [30321:30828](-), [<29469:30274](-)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(join(<10001..10805,10853..11359,11411..11763,
                     11823..>12017))
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..22017
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22017
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            join(<154..170,223..428,487..564,617..1080,1141..>1398)
                     /locus_tag="M747DRAFT_335381"
                     /product="NAD(P)-binding protein"
     gene            <154..>1398
                     /locus_tag="M747DRAFT_335381"
     CDS             join(<154..170,223..428,487..564,617..1080,1141..>1398)
                     /codon_start=1
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF13460"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 34.2;
                     E-value: 3e-10)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_335381"
                     /note="EggNog:ENOG41"
                     /product="NAD(P)-binding protein"
                     /protein_id="ncbi_M747DRAFT_335381-T1"
                     /transl_table=1
                     /translation="MAKIFLTGASGYIGGDVLHALKSALPTCQYTVLLRDEAKAQKLSQ
                     AYPDVQVVLGDLDASSTLEQQAREADIVIHTASSNHVKSAEAIARGLTAPERPKPGHWL
                     QISGASVLSIPDIVASAFGGPSNKIYSDVDGADELRELIRQYSAKRVVDNLVLSLPHTS
                     SRPKTALIFPPIIYGRGRGPINQRSIQIPELARVTMQRRGGVQVGRGEATWSNVHISDV
                     SNIFVKLAEKALQSEEGKLWNENGLYFPGSRAISFGSISARVAQEVKKLGLAESESVTE
                     ISHEEADSLTPHGGVLWGTNAQQVAQRAAKYLKWVPEGRTLEEEIPHTVLAEAQRLGLK
                     "
     mRNA            join(1701..2019,2095..2553,2602..3047,3097..4230)
                     /locus_tag="M747DRAFT_326312"
                     /product="hypothetical protein"
     gene            1701..4230
                     /locus_tag="M747DRAFT_326312"
     CDS             join(1758..2019,2095..2553,2602..3047,3097..4140)
                     /codon_start=1
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR021858"
                     /db_xref="InterPro:IPR036864"
                     /db_xref="PFAM:PF00172"
                     /db_xref="PFAM:PF11951"
                     /locus_tag="M747DRAFT_326312"
                     /note="GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0000981 - DNA-binding transcription factor
                     activity, RNA polymerase II-specific [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of transcription,
                     DNA-templated [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_326312-T1"
                     /transl_table=1
                     /translation="MTSSKQSGRRTRRSHALGACRTCRRRHAKCDQKRPTCQMCRATGV
                     VCEGFVDEIRWMSDRKSQPSSGTTAKKANDPEKQGPRRHLYTEKSRVSMSDALSADLVS
                     GSIDASLAEIETRSRDTERPSQGDIVVGPFAVLDFSLTEPKSASRAHPTDETTVANDVI
                     LPSGDTLAEGASGVSPALSQESIAYMNDLLQWSDILSLDPQLQSATLSGTFDLGDWLPL
                     DLGTQAPMLEHNLLGEAPNNASKMVPPVDSNPPDVLADAHYLLRHFQDHVISRMMAVPL
                     DQKSPWKILNVPSAVVTYSDITFLGSQNITHARLANLYCLLACSALHLTVNPSMRTSDS
                     TERWKPVAEYAYHLAKDHMQMSLKHETQEPKKAKYKDQLMAICALTEFAILSSQQQDAR
                     CYMIDAERLLRLRGLPKQRISQKARLLHHTYTWLRIVGESTYALHNYTPSDAFMEALKY
                     RFRYQKVENTQAAGYRTSRLDDFLRLDRRPSDSDLDIDEPKEDDVGLYDIHLQDSRKYP
                     ATLYSQIYGVSETWLSLVSQTTRLANVMETFRVAREMRQGNNASLEAWEALHRRSARLE
                     SMVCTFASRRTEDNICDSTNILAKSHGCLLQALNSALVIFFYRRIRQVHPAILESQVDK
                     VISSLNEFDVALVEADHTGPGTVWPLFIAGCEATTPERRQSITLLLDKGEARCGFSAYH
                     TVRDVMNQVWDKQDAHFTRSRGETFPTWLDVVKSKQIWPILA"
     mRNA            complement(4191..5430)
                     /locus_tag="M747DRAFT_326313"
                     /product="dihydrodipicolinate synthase"
     gene            complement(4191..5430)
                     /locus_tag="M747DRAFT_326313"
     CDS             complement(4229..5149)
                     /codon_start=1
                     /db_xref="InterPro:IPR002220"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="InterPro:IPR020624"
                     /db_xref="PFAM:PF00701"
                     /locus_tag="M747DRAFT_326313"
                     /note="EggNog:ENOG41; GO_function: GO:0016829 - lyase
                     activity [Evidence IEA]; GO_function: GO:0003824 -
                     catalytic activity [Evidence IEA]"
                     /product="dihydrodipicolinate synthase"
                     /protein_id="ncbi_M747DRAFT_326313-T1"
                     /transl_table=1
                     /translation="MTVTQQTPALHGIMVALITPFTDDKTQIDAARLKSHIDHLIGAGV
                     HGLVPGGSTGEFTTMTREERKQLTELCVEYAAGRVPVVAGTGSTSTEEAVDLARHAAQA
                     GAAAVMVVPPFYDPLNVEQLTELMSEIHEASQLPIVYYNIPSASGLTLTPQQIADLSKV
                     GVKYLKDTSGNAPAYTELVFGLSDQITAFNGWDTLTFYGLAAGSPGAVWGAANIIPELA
                     VELWNAVSVEGDLKKGRELWAKAWPICKFLESHNYAAAVKTGVELRGQATGGLRKPFAL
                     LKDDLQSELAQLMVNANVNVVKRSS"
     mRNA            join(5629..5882,5936..6135,6188..7458)
                     /locus_tag="M747DRAFT_268859"
                     /product="aldehyde dehydrogenase"
     gene            5629..7458
                     /locus_tag="M747DRAFT_268859"
     CDS             join(5752..5882,5936..6135,6188..7374)
                     /codon_start=1
                     /db_xref="InterPro:IPR015590"
                     /db_xref="InterPro:IPR016161"
                     /db_xref="InterPro:IPR016162"
                     /db_xref="InterPro:IPR016163"
                     /db_xref="InterPro:IPR029510"
                     /db_xref="PFAM:PF00171"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 505.1; E-value:
                     2.4e-153)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_268859"
                     /note="GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]; GO_function: GO:0016620 - oxidoreductase
                     activity, acting on the aldehyde or oxo group of donors,
                     NAD or NADP as acceptor [Evidence IEA]; GO_process:
                     GO:0055114 - oxidation-reduction process [Evidence IEA]"
                     /product="aldehyde dehydrogenase"
                     /protein_id="ncbi_M747DRAFT_268859-T1"
                     /transl_table=1
                     /translation="MADSLFVDITTPNGRQYQQPTGLFINNEFRPSSSGQTIVSLDPAT
                     DKPIATVHAATAEDVDAAVQAAKAALSHPSWKLLPATERGQLMGRLADLMEENRALFAA
                     IDAWDNGKPYHVALTEDLTEAITTIRYYSGWADKTFGQTISTTPQKFAYTIRQPIGVVG
                     QIIPWNYPLSMATWKLGPALACGNTVVIKAAEQTPLSILVLATLIKKAGFPPGVVNVIN
                     GYGKEAGAALVQHPLVDKIAFTGSTATAREIIKMAAGTLKNITLETGGKSPLIVFPDAD
                     LEQAVKWSHFGIMSNKGEICTATSRIFVHRSILASFLEKFKKEIETTSKIGDQWDENTY
                     QGPQVTRAQYERVLSYIETAKKEGATLVTGGKAYTPKDEKNAKGYFVEPTVFTDVTDDM
                     RICQEEVFGPVVVILPFDSEEESVRRANDTTYGLGAAVFTTDLERAHRVAADIEAGMVW
                     INSSQDCDPRVPFGGVKQSGIGRELGEAGLEAYSQVKAVHVNMGSRL"
     tRNA            complement(7945..8015)
                     /locus_tag="M747DRAFT_t254"
                     /product="tRNA-Gly"
     gene            complement(7945..8015)
                     /locus_tag="M747DRAFT_t254"
     CDS             complement(join(<8221..9147,9200..9331))
                     /codon_start=1
                     /db_xref="InterPro:IPR000537"
                     /db_xref="PFAM:PF01040"
                     /locus_tag="M747DRAFT_289161"
                     /note="EggNog:ENOG41; GO_component: GO:0016021 - integral
                     component of membrane [Evidence IEA]; GO_function:
                     GO:0016765 - transferase activity, transferring alkyl or
                     aryl (other than methyl) groups [Evidence IEA]"
                     /product="UbiA prenyltransferase"
                     /protein_id="ncbi_M747DRAFT_289161-T1"
                     /transl_table=1
                     /translation="MQRKLELVDFTCFYEFCTYLLGAAGALLESDVVKTRPNNTRAYKE
                     EWSWKDLVLTIWLFTADDFTTFVIPETAFGICAALSGPLLTDDNTPDLLSVVSRIPIVM
                     LWNWLNLFVFNLANQRHPDSVAEDKINRPWRPLPAGRISILQTRRLLLLAIPMVLASSV
                     YLGAWEETALLYTLNWVYNDLSGGDDGFILRNVLLALAFSQYNKGSLRVATGTGFDILP
                     RAWRWIWVTSAVIGTTMHIQDIKDVEGDRAKNRRTMPIVMGDGPARWSVAVPVAIWSVV
                     CPAFWELDVARYVLPVAVGMTIAGRILLLREKAADKRTWKMWTAWTAVIWVLPLFKNAS
                     VFVRFGKKLGVV"
     mRNA            complement(join(<8221..9147,9200..9345))
                     /locus_tag="M747DRAFT_289161"
                     /product="UbiA prenyltransferase"
     gene            complement(<8221..9345)
                     /locus_tag="M747DRAFT_289161"
     mRNA            complement(join(<10001..10805,10853..11359,11411..11763,
                     11823..>12017))
                     /locus_tag="M747DRAFT_361122"
                     /product="terpenoid synthase"
     gene            complement(<10001..>12017)
                     /locus_tag="M747DRAFT_361122"
     CDS             complement(join(<10001..10805,10853..11359,11411..11763,
                     11823..>12017))
                     /codon_start=1
                     /db_xref="InterPro:IPR002060"
                     /db_xref="InterPro:IPR008949"
                     /db_xref="InterPro:IPR017825"
                     /db_xref="InterPro:IPR019845"
                     /db_xref="PFAM:PF00494"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="M747DRAFT_361122"
                     /note="GO_function: GO:0016872 - intramolecular lyase
                     activity [Evidence IEA]; GO_function: GO:0016740 -
                     transferase activity [Evidence IEA]; GO_function:
                     GO:0016765 - transferase activity, transferring alkyl or
                     aryl (other than methyl) groups [Evidence IEA]; GO_process:
                     GO:0009058 - biosynthetic process [Evidence IEA]"
                     /product="terpenoid synthase"
                     /protein_id="ncbi_M747DRAFT_361122-T1"
                     /sec_met_domain="phytoene_synt (E-value: 1.5e-21, bitscore:
                     69.1, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MNQNGTRLCYSVREVPPTSFVSAPANYKRASSHCTYTIPAASALT
                     VLYYPFFTAQDRCKICILITIAILATLPWDSYLIRSAIWTYPPDAVVGLKILDIPIEEV
                     FFFAIQTYITSLTYCIFTKPLVRPMYLRSHLERRGTRYVVATVILALMGGGTACLLLGR
                     RMTYLGLILVWACPILLFQWMMSYPFLSELPWKPTITSICLPTLHLWFADSRAMGTGTW
                     RIEEGTKLNFRIGGLELESVRPTGALLDVGSNSSREALFFLVSNMMVVLGLVGCDYAYA
                     LQEYESLSQPASDVYITLRKALSLLARPLPIDASLISALSQAVYRLQEKSQSMFLGSAL
                     FQGQLRIDLIFLYSFCRVMDDLIDEAEDEQEARFWVTECRHLLDSTHRSEPHSDHFYTG
                     KKGEEHERLRQSISYLPPSHLSNDSFDDLLKGFEIDLKFNPQREAFPIQSEYCLDQYAG
                     FVAGTVGVLVFDLTLFHCGHYFIQDVPRLRRAAKDMGKAMQCINIARDIHRDAAIGRVY
                     IPTTWLGEVGLTPGDVLQCPNSPVTYDLQERMLQKADEYYQVSRGAMEELPRGVREPLR
                     ATVASYMDIGLLLRERKGTSLAQASKMKVPLVRRLKVGWLAML"
     mRNA            complement(join(12599..12908,12965..13190,13240..14213))
                     /locus_tag="M747DRAFT_289166"
                     /product="ISP domain-containing protein"
     gene            complement(12599..14213)
                     /locus_tag="M747DRAFT_289166"
     CDS             complement(join(12705..12908,12965..13190,13240..14042))
                     /codon_start=1
                     /db_xref="InterPro:IPR001663"
                     /db_xref="InterPro:IPR015879"
                     /db_xref="InterPro:IPR015881"
                     /db_xref="InterPro:IPR017941"
                     /db_xref="InterPro:IPR036922"
                     /db_xref="PFAM:PF00355"
                     /locus_tag="M747DRAFT_289166"
                     /note="EggNog:ENOG41; GO_function: GO:0051537 - 2 iron, 2
                     sulfur cluster binding [Evidence IEA]; GO_function:
                     GO:0016491 - oxidoreductase activity [Evidence IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_process: GO:0055114 - oxidation-reduction process
                     [Evidence IEA]; GO_process: GO:0044237 - cellular metabolic
                     process [Evidence IEA]"
                     /product="ISP domain-containing protein"
                     /protein_id="ncbi_M747DRAFT_289166-T1"
                     /transl_table=1
                     /translation="MWRLLGRSSNTSEKSSPPRSLPGSWYRSDAMYQLERRAIFSKRWM
                     LLTHSSRLTKPGDFLSFTISNFSFFLTRDREGSINGFHNICRHRAYPVVQARSGATSIL
                     SCKYHGWSYGLKGNLSKAPRFETVSNFDKSQHGLLPIHVHIDKAGFVWVNLEAGDPEVK
                     WEDDFQKIDEQPRMQDFDFDGEYTFDHYWEMDVEANWKLLIENYNECYHCATSHPLING
                     VSDLPRYRVEPKARYMEHHIFNKDNIDAQFRRSITYFYPTTSVTVTDKFFYIQRMIPVS
                     ATMSKIENEVYRHRDATDEEFANINAFYRQVLDEDRDLCVGAQENLSAGVFINGELHPD
                     KEKGPIHFQDHVKTMVMEHRRKEEEQGGEEIWPAVPKVTGEMRTGKLAEEERFCSQLEA
                     ASCMARSELAW"
     mRNA            complement(join(14273..14714,14768..15052,15111..15206,
                     15258..15845,15900..16150))
                     /locus_tag="M747DRAFT_299685"
                     /product="MFS general substrate transporter"
     gene            complement(14273..16150)
                     /locus_tag="M747DRAFT_299685"
     CDS             complement(join(14549..14714,14768..15052,15111..15206,
                     15258..15845,15900..16024))
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1137:Major
                     facilitator superfamily MFS 1 (Score: 361.5; E-value:
                     7.3e-110)"
                     /gene_kind="transport"
                     /locus_tag="M747DRAFT_299685"
                     /note="EggNog:ENOG41; GO_component: GO:0005887 - integral
                     component of plasma membrane [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="MFS general substrate transporter"
                     /protein_id="ncbi_M747DRAFT_299685-T1"
                     /transl_table=1
                     /translation="MSEPKNQPVEEPTIPPEEGVKGWLTVAGSFCALFSSFGFLNAIGV
                     FQTTYQQTSLKDYDASDISWIFAVQLALMWAPGPLWGRMIDTYGPIPVLWPCSILCVLG
                     LCMTSLAHEYYQIFLAQGLCFGIGAGGVFTSAMICVGQWFVRRRGLATGIAVSGSSLGG
                     VIFPIFLDRVINDIGFYGAVRYTALFVGIMLAIACLLIRSRLPRKEWNGKAAWVDLTLL
                     KDTAFGLYTAGAFFIMWGLWAPFDYISSMAENAGFSSTLALYLISIINAASIFGRLIPP
                     QLADVFGHFNVLTLCCFGTGVSMLCLWLPFNYHPSHAGIIVFSAVYGFVSGAVVSLMMP
                     CVAKVGDLQTLGQRFGTFQLIMSVSCLTGLPIMGAILEKQNYTDYSGLQLFGACCGILG
                     SVLIGAATFLLRKMRNTSKI"
     mRNA            complement(join(<16204..16377,16504..16647,16807..16917,
                     17025..17084,17176..17456,17552..17597,17696..>17752))
                     /locus_tag="M747DRAFT_247839"
                     /product="hypothetical protein"
     gene            complement(<16204..>17752)
                     /locus_tag="M747DRAFT_247839"
     CDS             complement(join(<16204..16377,16504..16647,16807..16917,
                     17025..17084,17176..17456,17552..17597,17696..>17752))
                     /codon_start=1
                     /locus_tag="M747DRAFT_247839"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_247839-T1"
                     /transl_table=1
                     /translation="MVVGMILESPSRSQSINDSELNCRITKEQCAMRPATYMQTDKDTP
                     CQIQPRGYSAEHLLDTAGGDPGRCSSQCKHPGGFWSNMLYYCTSYATKYRRVVITAIAD
                     VGHLQGTQAALTPNCEAILLKDGKDGIVQGTRLTIIGLASGLPGMFRIHPKFSDQKHLC
                     YDLSRTDAQVNTRSAFFSADGILASEFRYPAVVQHSGAMWAGIIPIMGSRVLRPGFPGV
                     ACSQPLCGIQQMAFCHCDDTVNFMPKATSVRIISATLVSQILVVFAPSDITRAEGPRRS
                     FSSKPRYLS"
     mRNA            18140..19599
                     /locus_tag="M747DRAFT_299686"
                     /product="CoA-transferase family III"
     gene            18140..19599
                     /locus_tag="M747DRAFT_299686"
     CDS             18163..19416
                     /codon_start=1
                     /db_xref="InterPro:IPR003673"
                     /db_xref="InterPro:IPR023606"
                     /db_xref="PFAM:PF02515"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189:L-carnitine dehydratase/bile acid-inducible
                     (Score: 346.4; E-value: 3.1e-105)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_299686"
                     /note="EggNog:ENOG41; GO_function: GO:0008410 -
                     CoA-transferase activity [Evidence IEA]"
                     /product="CoA-transferase family III"
                     /protein_id="ncbi_M747DRAFT_299686-T1"
                     /transl_table=1
                     /translation="MPNTRPLVRAACHNLSGMRHASTSATKKAGPLAGITVVSLEQAIA
                     APFCTRQLADLGARVIKVERPGVGDFARNYDTRVNGLASHFVWTNRSKESLALDLKKPS
                     DHSVLMRLLGRADVLVQNLAPGASARLGLSYDDLKAAHPSLIVCNISGYGPDGPYRDKK
                     AYDLLIQSEAGMLSVTGTGKEPAKVGISIADISAGSYAYSNILAALYQRERDPSKRGCN
                     IDISMLESMVEWMGFPMYYTYENAPGPTPAGASHAAIYPYGPFETGDGTVMLGIQNERE
                     WAKFCDIVLGQPSLATNERFVNNSLRSQNRDELKKIICDVFSSLSAEQVIARLDAAAIA
                     NASVNDMQGVWNHPQLKARQRWTDVKTPAGSVPALLPPGMTMGDEDTYGARMDAVPDVG
                     EHNKAILAELGLDEGTEK"
     CDS             join(19887..20056,20116..20892,20938..21004,21051..21237,
                     21282..21462,21517..21675,21727..21895)
                     /codon_start=1
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR007219"
                     /db_xref="InterPro:IPR036864"
                     /db_xref="PFAM:PF00172"
                     /db_xref="PFAM:PF04082"
                     /locus_tag="M747DRAFT_145284"
                     /note="EggNog:ENOG41; GO_component: GO:0005634 - nucleus
                     [Evidence IEA]; GO_function: GO:0000981 - DNA-binding
                     transcription factor activity, RNA polymerase II-specific
                     [Evidence IEA]; GO_function: GO:0008270 - zinc ion binding
                     [Evidence IEA]; GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     transcription, DNA-templated [Evidence IEA]; GO_process:
                     GO:0006351 - transcription, DNA-templated [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_145284-T1"
                     /transl_table=1
                     /translation="MSSQESSGHRQVRTRAKQACLHCNKRRIRCNVLQMRPCQNCLALN
                     VPCEIGVSKRGKYPRKKSARQQTDGNSVQLPASSAKGGNHSFTVSAGDKSDAKESHVHP
                     IPGDAASAHPTVFFGESSPLTVVIDEGRRSPEKGTNEMHMTRFHYAIPEKLDAFNTRDE
                     AFRAHKIKQEGQLRADGAFSYPPPETCETLLRAYFDWFHPCFPILDCAAVYESYVQGSM
                     SPLLLQAILFIGVSLCTDEVFARTEFSVRYWAKFLFYSRAKAIYDAEWESNKTVKIQAL
                     FLLSFWRGGPSEERDIRFWLGIAIDLAQKRGMHLMSKFPFASRREAGLWKRIWWSLYTR
                     DQQSAAALGLPPHIRDEDCDVDMLEPEDIREEAVGGQSHFGVQCIEDLSYPAEMAKLAK
                     LLRSIVSTQYSPLGPSSNGASRAALHQQLRDWEANMPLELKLENATTPRAKFLAGLLHM
                     TYQNLYILLYRPSFLHPPDGDLDSQGQIALNAATKSTRVLEDMLSHNLVQHGSSHLIIH
                     VFLTLCIHTIHFRRTSGTGRKLAEHRARLCLLSLQELQKSWDLENWVLNLFF"
ORIGIN
        1 gaatcaccta ccacatcgat atctgcccct cagaaacaac aacccctcat cacatcattt
       61 tactttgaat ttagctgttc ctacacgcct tgactaaaat ccttttttct tgccttgcac
      121 tccctagagt cacatatgaa cattccagtc acaatggcga aaatctttct gtaggtacat
      181 ccagggattc gtcctcttcc ttgctactaa cagaaatcat agtacaggag cctcaggtta
      241 tattggaggg gatgtcctcc atgcgctgaa atcagccctt ccaacttgcc agtatacagt
      301 cttgctgaga gacgaggcga aggctcagaa actctctcaa gcgtaccctg atgtacaagt
      361 agtcctggga gatttggacg cctcttccac tttggaacaa caggcacgag aagcagatat
      421 cgtcatccgt gagtgttctt gcttcaattc tttctgcctt ctgctaatat tggcctcctt
      481 tctcagacac cgcaagctca aatcacgtaa agagcgccga agccatcgcg cgtggattga
      541 ctgcaccgga aagaccaaag ccgggtaatt acctcccatt cgttccgtcc cctcacactt
      601 ctcatgaatc aagcaggtca ctggcttcag atatcaggcg caagcgtcct ttccattcct
      661 gacattgtag ccagcgcctt tggagggccc tccaacaaga tttacagcga tgtcgatggt
      721 gctgatgagc tgcgggagct cattcgacag tactctgcca agcgtgtggt tgacaatcta
      781 gtcctcagcc ttccccatac ttcctctcgt cctaaaaccg cgttaatatt tcccccgatc
      841 atttacggtc gcggtagggg accgattaac cagcggagca tacaaatccc ggagctggca
      901 agagtgacca tgcagcgacg gggcggggtt caggtgggca gaggagaagc cacatggagt
      961 aatgtgcaca tctcggatgt cagcaacatc tttgtgaagc tggccgagaa ggctttgcaa
     1021 agtgaggaag ggaaattgtg gaatgagaac gggttgtatt tccccggttc cagggctatc
     1081 gtaagttctt acatgctccg acctaagcac agaacaaggt acattctaac gagagtacag
     1141 tcattcggtt ccatctcagc acgagtggcg caagaagtga aaaagctcgg ccttgctgag
     1201 tccgagtcgg taactgagat cagccatgaa gaggccgatt cactcacgcc tcatggcgga
     1261 gtgttgtggg gaaccaatgc ccagcaggtg gctcagcgag cggccaagta cctgaaatgg
     1321 gtccccgaag gaaggacgtt ggaagaggaa atcccacaca ctgttcttgc cgaggcccag
     1381 agactgggac tgaaatagat ctatcttgga gttattagaa tacctgaata aattcactta
     1441 caatacaatt gtccattccc accgaagtca acatatctag ttatcgccca tacaactcgg
     1501 tgtcatcaag cttccaagat actgaaaggc taaacccggg agagcaggtc cttccgacgc
     1561 tgttctggtc cgaacaggaa ggagattccg ccccgccgga accgcctgcc tgcccggtcg
     1621 ggccacaccc tcctttctgg gggacctgct aataattgct tcaccttcca gctccagggc
     1681 cacccgactc ataccccaga ttctgttcga ttaccctttc tttccgtttt cgttgataat
     1741 gccctgctct gagtgacatg acttcctcca agcaatcagg ccgccggact cgtcgcagtc
     1801 atgccctggg agcctgcaga acgtgtcgaa ggcgtcatgc caaatgcgac caaaagaggc
     1861 ctacctgcca gatgtgtcgg gcaacaggtg tggtatgtga ggggttcgtt gatgagatcc
     1921 gatggatgtc cgatcggaag tcccagcctt cttcggggac aacagctaag aaggcaaatg
     1981 atccggagaa gcaggggcct cgacgccatc tctacacagg ttgatcaccc tctctcatac
     2041 atcgatgatc tgatcaccgg cttcaaaatg gtaaagctaa tgtatagaca ttagaaaagt
     2101 cgagagtctc catgagcgat gcattgagtg cagacttggt gtcgggctct attgatgcct
     2161 cattggctga gatcgaaaca agatcccggg atacggagag gccctcacag ggcgatattg
     2221 tagttggacc atttgctgtg ctggacttta gccttaccga acccaaatct gcaagtcggg
     2281 ctcatcccac tgacgagact acggtcgcaa atgatgtgat tctaccgtcg ggggataccc
     2341 tggctgaagg cgcttccgga gtcagtccag ctctgtcgca agagtcgatc gcctacatga
     2401 atgacctgct gcagtggtca gatattctta gcttggatcc tcagttgcag agtgctacac
     2461 tatctggcac attcgacctg ggcgattggt tgcccctgga tttggggaca caagccccta
     2521 tgctggaaca taatctcctt ggcgaagctc ctagtctgat ggatgataca gcagctctct
     2581 accattgtgt ccctgggcaa gacaatgcct ccaagatggt gccgccggtt gatagcaatc
     2641 cacctgatgt actagcagat gctcattacc tactacgaca tttccaggat catgtcattt
     2701 cgcgtatgat ggccgttcct ctagaccaga agtcaccttg gaagatactc aatgtgccat
     2761 ctgctgttgt aacatatagc gatatcactt ttctggggtc gcaaaacatc actcatgctc
     2821 gattagccaa tctgtactgc ctcttggcct gttcagccct ccatttaacg gtaaaccctt
     2881 ccatgaggac ctcggactca acagaacgat ggaagccggt agcggaatat gcttaccatc
     2941 tggcaaaaga tcacatgcag atgtctctga agcatgaaac acaagagcca aagaaggcca
     3001 aatacaagga ccagctcatg gcaatttgcg ccttgactga atttgctgta tgattcctgt
     3061 ctaactttgt tcgaggtagc ttactgaggg aaacagatcc taagtagtca gcagcaggat
     3121 gcaagatgct atatgatcga tgctgagcgg ctgctccgcc tccgagggtt gcctaaacaa
     3181 cggatttctc aaaaagcacg cctcctacac cacacatata cgtggctacg aattgtaggt
     3241 gagagcacct acgctttgca caactacacg ccctcggatg cctttatgga ggctctcaaa
     3301 tatcggtttc ggtatcagaa agtcgaaaat actcaagcag ctgggtaccg aacatcacgc
     3361 ttggacgact ttttgcgcct cgatcggcgc ccgtccgata gcgacctgga cattgatgag
     3421 ccgaaggagg acgacgttgg cctatatgat attcatttgc aggattcgcg caagtatcct
     3481 gccacactat atagccagat ttacggggta tcggagacgt ggctcagctt ggtatctcaa
     3541 acaacacgcc tggccaatgt aatggaaacc tttcgagttg cgcgcgaaat gcgtcaaggg
     3601 aataatgcaa gtctcgaagc atgggaagca ttgcatcggc gcagtgctcg tctcgagagc
     3661 atggtgtgca cattcgcgtc caggagaaca gaggacaaca tatgcgattc gaccaacata
     3721 ttggccaagt cacatggatg ccttttacag gctttaaatt ctgcgctggt tatcttcttc
     3781 tatagacgca tccgtcaggt ccacccggct attttggaga gccaggtgga caaggtgatc
     3841 tcatcgttga acgagtttga tgtagcacta gtggaagcag atcacaccgg cccaggtaca
     3901 gtctggcctc ttttcattgc tgggtgcgag gcgacgacgc ccgaaaggcg gcaatcgatc
     3961 acactgctgc tagacaaagg cgaagcacga tgtggatttt ctgcctatca tactgtccgg
     4021 gacgtcatga accaggtatg ggacaaacaa gatgcgcact ttacacgaag cagaggagag
     4081 acttttccga cctggcttga tgttgtcaaa agcaagcaaa tatggcccat tctagcatga
     4141 tgaccgccgg ggtctgttac aaggcgctac aagagatacg atgacatgtc ctcataaatt
     4201 tatttttcta tatccaatgg cgactatttc atgacgaacg cttgacaaca ttaacattcg
     4261 cattcaccat caactgggcc agctcgctct ggagatcatc cttcaagagg gcgaatggct
     4321 tccgcaaccc accagtggcc tgtcccctca gctccacgcc tgtcttgacc gctgcagcgt
     4381 aattgtgcga ctcaaggaac ttgcagatcg gccatgcctt ggcccacagt tcccgaccct
     4441 tcttgaggtc tccttcaacc gaaacggcat tccaaagctc caccgccaac tctgggatga
     4501 tgttggcagc accccaaact gctcccggcg atccagccgc cagtccatag aacgtaaggg
     4561 tatcccagcc attgaaggcg gtgatctgat ctgacaaccc gaacaccaat tccgtgtagg
     4621 ctggagcatt tccagatgtg tctttgaggt acttgacgcc gaccttgctc agatccgcga
     4681 tctgctgcgg tgtgagggtc aacccgctgg cagaggggat attgtagtag acaatgggca
     4741 gttgactggc ttcgtggatt tcggacatga gctcggtcaa ttgctccacg ttcaaggggt
     4801 cgtagaatgg cggcacgacc atgacagcgg ccgcaccggc ctgcgcggca tgacgtgcca
     4861 gatccactgc ctcctcagtg gaggtactgc ctgtgcccgc tacgacaggg acacggccag
     4921 ctgcatactc gacgcagagc tcagtcagtt gcttgcgttc ttcgcgggtc atggtggtga
     4981 attcgcctgt gctgccgccc ggcacgaggc catgcacgcc ggcgccgatc aggtggtcga
     5041 tgtgggattt gagtcttgct gcgtcgatct gggtcttatc gtctgtgaag ggggtaatca
     5101 gggcaaccat gatgccgtga agggcggggg tttgctgtgt gacagtcatg ttggttgtag
     5161 ttgttgattg gtatagttga ggcaaggaag aatgacgtga aggactgaaa gaacaattat
     5221 tgaaggactc gtgagtcgag tctcgagggc atttttattt catgcggcga cgggactgcc
     5281 ttccctctca atccctcctt catgtctata caatactttt gatgattgtt ctggcagtat
     5341 gaacgaagcc ctaactgtct ggataggatc tcagaggggt aacaagacat gccggaacca
     5401 cctgcccatt ctggcgatgc gggattaccc accggcaggc agttccggca tgcagtgggg
     5461 aggcattagc gcatccaccg gcgccaaact atcgattgcg tctcgacatc aaagaagtga
     5521 ggggtaatcg gacgatctta tccttgttat cgccttatcg gacgggggat ttgctgacta
     5581 gtgacaaacg tcaattgcca agtggtctgc gcggaggcac atcccacatc cggaacagga
     5641 agttctagcc aagtagcata tatcaagaca ggacactctg tctcgcgctg attatcactg
     5701 tcttctgcta ctactgttat ctgttatttc gaagaagagt aagaagagaa catggcagac
     5761 tccctctttg tcgacatcac cacccccaat ggtcggcagt accagcagcc gaccggcctg
     5821 ttcattaaca atgagttccg tccttcgtcc agtggccaga ccatcgtgtc tttagatccg
     5881 gcgtaagacc tacgaattct tgtctccttc tacgcctcca tgctaatctt cacagtaccg
     5941 acaagcccat cgccactgtc cacgccgcaa cagcagagga tgtcgacgcc gccgtccaag
     6001 ctgccaaagc ggccctgtcg cacccttcat ggaagctcct ccctgccacc gagcgcggac
     6061 agctgatggg tcgtctggcc gatttgatgg aagaaaaccg ggcactattt gctgccatcg
     6121 atgcttggga taacggttcg tatactcacc atcctcaccg atatgcagac actgacttgg
     6181 ccaacaggaa aaccctacca cgtcgccctg accgaggacc tcaccgaagc catcaccacc
     6241 atccgctact acagcggctg ggccgataag acctttggac agacgatcag caccactcct
     6301 caaaagttcg catacaccat ccgccagccc atcggcgtcg tcggacagat catcccatgg
     6361 aactacccgc tctcgatggc gacgtggaag cttggtcccg cgctcgcctg cggaaacacc
     6421 gtcgttatca aggccgctga acaaactccc ctcagcatcc ttgtcctcgc aacactcatc
     6481 aagaaagccg gattcccacc cggagtggtc aatgtcatca atggctacgg aaaagaagcc
     6541 ggcgctgcgc tggttcagca cccgctcgtc gataagattg ccttcacagg ctctactgcc
     6601 accgctcgag aaatcataaa gatggctgcc ggcacattga agaatatcac ccttgagacg
     6661 ggcggaaagt cgcccttgat cgtattcccg gatgcggatc ttgaacaggc ggttaagtgg
     6721 tcgcatttcg gaatcatgtc caacaagggc gagatctgca ctgctacgtc gaggatcttc
     6781 gttcatcgta gtattctcgc ctccttcttg gagaagttca agaaggagat cgagacgact
     6841 tccaagatcg gcgaccagtg ggacgaaaat acctatcagg ggccgcaagt tacccgggca
     6901 cagtacgagc gcgttctatc gtacatcgaa acagccaaaa aggagggcgc tacgctagtt
     6961 accggcggca aggcctatac tcccaaggac gaaaagaacg cgaagggcta ctttgtcgag
     7021 ccgacagtgt tcactgacgt gacggatgac atgcgcatct gccaggaaga agtattcggt
     7081 cccgtggtgg tcatcctgcc attcgactcg gaggaggaat cggtgcgtcg cgccaacgat
     7141 accacgtatg gtctgggcgc ggcggtcttc acgaccgatc tggagagggc gcatcgcgtc
     7201 gcggcggata tcgaggccgg tatggtctgg attaatagta gccaggattg cgatcccagg
     7261 gtccctttcg gaggcgtgaa gcagagtggt attgggcgcg agctgggaga ggcgggactg
     7321 gaggcgtact cgcaggttaa ggcggtgcat gttaatatgg ggagtagact gtaagctact
     7381 atagagatgg gagcatgctt tgacgaatag attatgaagt tatattcaat gttttgggta
     7441 ggttggttgt gtcctgttac tgtccgtaag ctggtagtat agtatatgga acgagcatgt
     7501 ttacgtcttg ctggagactg gaaattccat ctacacaatc tagtaatacg atgcctacgc
     7561 caagtattga aaggttgaaa tgatgatagt aggggcagta gtaattttgt tgctcgtctc
     7621 agcagcttca tagagaaaat tacctctacc tgaacggagc agatatatat atctgattta
     7681 acacaacaat cgtgtccaat tagtattcct gaagtggcct cgaccagaat gattagtaat
     7741 atatttcgtg gtggatcctc tgtttaagag attggctttt catcgatggt agaaaacaaa
     7801 ttagatttgt cgttctctgc atcgtccatt gctgcccatc tcaatccgcg acgctgtaaa
     7861 aaatgggttt tccgcagaag aaaatagtag tcaggaacaa ccccactatg gacgctatcg
     7921 ggtaaaagca aaaagaaatt cgcttgcatc atccgtgaat cgaacacggg cctcatcgat
     7981 ggcaacgatg aattctacca ctagaccaat gatgctactg cttgtagttc ttggcacttg
     8041 aatgatctaa gatctagtaa actggaagaa atttcagaag accatctgat ttctaaaata
     8101 ctggatctgt caactctccc gtgcgatata gctacccgtc atgtcatatt tacttaagtg
     8161 acatgaccac aacagcctgc aagcgaagta aattctcgct cacttggctt gagcaatgcc
     8221 tcacaccacc ccaagcttct taccaaacct gacaaaaaca ctagcattct tgaacaaagg
     8281 aagcacccaa ataactgcag tccacgccgt ccacattttc cacgtgcgtt tatcagcagc
     8341 cttttcccgc aataacaaga tcctcccagc aatagtcatt cccaccgcaa ccgggagaac
     8401 gtacctggca acgtctagct cccaaaacgc aggacaaaca acggaccaaa ttgcaacagg
     8461 aactgcaacg gaccaccggg ccggcccgtc acccatcaca atgggcattg tccggcggtt
     8521 cttggcacgg tctccttcca cgtccttgat atcttgaata tgcatcgtcg tgccgatcac
     8581 ggcactggtg acccagatcc accgccatgc tctagggagt atatcgaatc cagttccggt
     8641 cgcaacacgt aatgatccct tgttgtattg gctgaacgcg agggcaagaa ggacattccg
     8701 tagaatgaac ccgtcgtcac caccgctgag gtcattgtat acccagttaa gggtgtaaag
     8761 gagagcagtc tcctcccatg cacctagata cacgctggat gcgagcacca ttggaattgc
     8821 aagtagaagc aaccggcgag tctgcaggat gctgatccga cctgccggta gtggtctcca
     8881 gggtcggttg atcttatctt ctgccacgga gtccgggtgc ctttgattcg ccaggttaaa
     8941 cacaaacagg tttagccagt tccagagcat gacaatgggt atccgactaa cgactgagag
     9001 taagtccgga gtgttatcgt ccgtcagaag cggcccggaa agagcggcgc atatcccgaa
     9061 tgctgtttca ggtatgacaa atgtggtaaa gtcatccgcg gtaaatagcc agatagtcaa
     9121 gacaaggtcc ttccaggacc attcttccta tacacttgtg agccttctgg aaacatgagt
     9181 aatagcaatg ttcactcact ttgtaagccc ttgtattgtt tggtcttgtc tttacgacat
     9241 cgctttcaag caaagcacct gcagcgccga gtaaataagt gcaaaactcg tagaagcaag
     9301 taaaatcaac aagttccagt ttcctctgca ttttagattt tattctgctt acgcagtata
     9361 gagatgtctg cgtcggtgtt tgaaaagtat tcttcagaag gctcccagtc ttgggtgctt
     9421 agcaccctta tattcgtgga accatatcag gtcaaccttc tagtgggcac tgaaaagatt
     9481 gtgagtatcc cggaaatctc agggtcgctt tttcagctct tgtctgcgga atttttgcag
     9541 tggctggctg tatcaatctc tagctagacc tatcggtaaa gccggagagt tgttgtggaa
     9601 gacaaggcta agcaaaagac gaggttttgg ttgtccttgc cgatgacgct ctcttgatac
     9661 aagtcgtggc cgaaccgttg cagagctgaa taacgccaca catgctcttg tcagacgggt
     9721 ggacagtagc gccgaggcga tttcttcaga ctgtcagata aatctcatct gtgaagttag
     9781 ctgaaacccc cgggcctagt tgtctgcgcc ggctggtgca aaagccaagg tcccaagaac
     9841 agatgtggtc attccagccg atagacgaga gctgacaata ggacaagagt gtcagcacta
     9901 gcgttctgat gcctgacgag ataaatcaca tattcggcct gaatgaagca gtgacctgtg
     9961 aaaaatatgt gtagcacaca attcaacata cagagttcag ttataacatc gccagccaac
    10021 caacttttag ccgtcgcacc aaaggcacct tcatcttcga cgcttgcgcc aggcttgtgc
    10081 ctttccgctc cctcagcagt agtccaatat ccatatagct cgccacggtt gcccgcaatg
    10141 gctctcttac gccccgaggt agctcctcca tcgcccctcg gctgacctga taatattcat
    10201 ctgctttctg cagcattctc tcctgtagat catacgtgac tggggagtta ggacattgta
    10261 atacatctcc cggagttagg cccacttcgc ccaaccatgt tgtaggaatg tatactcgtc
    10321 cgattgctgc atcgcgatgg atatcacgtg caatattgat acattgcatg gctttcccca
    10381 tatccttggc cgctcgcctc aatcgcggta catcctggat aaagtaatga ccgcaatgga
    10441 ataaggtaag gtcgaagacc agtacaccga cagtgccagc tacaaatcct gcgtattggt
    10501 ctagacaata ctccgactgg atcgggaaag cttctctctg gggattaaat ttgaggtcga
    10561 tctcaaaccc ttttaaaaga tcatcaaaag agtcattaga tagatgtgag ggaggaaggt
    10621 agctgataga ttgacgtagt ctttcatgtt cctccccctt tttaccagtg taaaagtggt
    10681 cggaatgtgg ttcactgcga tgggttgaat ctaggagatg cctgcactct gtaacccaaa
    10741 atctggcctc ctgttcatcc tcggcttcgt caatgagatc atccatgacg cggcagaagg
    10801 agtacctatg catgtcagaa caatgaagca cgtttggact aaggggtaat acaggaatat
    10861 cagatcaatg cgcagctgac cctggaataa tgcgctgccg agaaacatgc tctgactctt
    10921 ctcttgcaga cgatatacag cctgggacaa tgcagatatg agagatgcgt caattggaag
    10981 cggcctggcc aataaggaca gtgcttttct taatgtaatg tagacgtctg acgctggctg
    11041 tgatagggat tcgtattctt gaagagcgta tgcgtagtca cacccaacca gtcctaacac
    11101 gaccatcata ttgctcacca gaaagaagag cgcttctctg ctactgttag atccgacgtc
    11161 taataatgca ccggtgggcc tgactgactc aagttctaga cctccgatac gaaagttcaa
    11221 ttttgtgccc tcctcgatcc tccaagtccc ggtacccata gcacgtgaat ctgcaaacca
    11281 gaggtgtagc gtggggaggc agattgaggt gattgttggt ttccagggaa gttcggatag
    11341 aaaagggtaa gacatcatcc tgtgttctcg catgagcacc tcaatggatt cacgcgtaga
    11401 ccaaacatac cactggaata gcaggatagg acacgcccac acaagaatca ggcctaggta
    11461 agtcatacgc cgtcccaaca gcaggcacgc tgtcccacca cccatcaatg ccaaaatgac
    11521 agttgctacc acatatcttg ttccacgtct ctccagatgt gaccgaaggt acatgggtcg
    11581 cacaagcggc ttagtgaaga tacagtatgt caagctcgtg atgtatgtct gtatggcgaa
    11641 aaagaaaacc tcttcaatcg gaatatcaag tatcttgagg ccgactactg cgtctggcgg
    11701 ataagtccag atagcggacc gtatgaggta ggaatcccac gggagcgtcg cgagtatggc
    11761 aatctgtcat tcccggtcat atcaactgaa gttgtccttg ccgcagggta aaattggtgt
    11821 accgtaatta ggatgcatat cttgcatcga tcttgtgcag tgaagaatgg atagtacagc
    11881 actgtcagtg ccgacgctgc agggatggta taagtgcaat gactgcttgc gcgcttatag
    11941 ttagcaggtg cagaaacaaa gcttgtagga ggtacctctc ttacagaata acatagtcga
    12001 gtcccatttt gattcatggt tatctctcat tcccttatgg cgactactga gcttatggaa
    12061 catatatcag tcaaagggcg ttcagtcctc tctgcaaggt ttagccgaat cctgttttcc
    12121 taccccagct tccggaaagg gaccatctgc ggatgcgtct ctgctttatg aacgttggaa
    12181 agtttgctct gggatgctca ttgccaccca taaaacaggg tagaattgag aatggctagt
    12241 taagttaatg ctaagtagtt cagaaactgt ccacctgtcg tcaatcatat aaggaaatgt
    12301 cctcactggg tatccgatcg acagaccagg gaggctctga cgtactctga cctcatgaca
    12361 ggagtaagct gaccgggtag tgagcaatgc atgaaataat gaccagctgc tctttttcaa
    12421 cgttattgag ctgtggcgac aaagcacggg attgacgcga cgaacgcatg agtggaaaat
    12481 agtagtaagt atgaagctgc agtgggagag ccaattaggg aaaaggggat gggttacgtt
    12541 atcggagtag atgagggaac tcccccaccc ttgacagttg ggtgggtatg ttttcattct
    12601 ccaaatcaac acagtctgac tgaagtgact gctcaatgca aatgtctcta atatgcaatg
    12661 ccccgaacgc ttatcacttt ataacatcac attcagataa aacattacca agcaagctct
    12721 gatcgggcca tgcaactggc cgcttccagc tgagaacaga acctctcctc ctctgccagc
    12781 ttccctgtcc tcatctcccc agtcactttg ggaacagctg gccagatttc ttccccgcct
    12841 tgctcctctt cttttcgccg gtgctccatg accattgtct tgacatggtc ttgaaaatgg
    12901 atgggtccct gctcacaatt agcgcttgct aattttacac ctgtctggac agtgtcataa
    12961 ataccttttc cttgtccggg tggagttcgc cgttgatgaa cacccccgcg ctcagatttt
    13021 cttgcgctcc aacacagagg tcccgatctt cgtctaagac ctgtcggtaa aacgcgttga
    13081 tattggcgaa ttcctcgtcg gtggcatctc tgtgtcgata tacttcgttt tcgatcttgc
    13141 tcattgtcgc gctaactggg atcatgcgtt gaatatagaa gaatttgtcc ctgcttgtgt
    13201 caattgacca tcgaccttcc ctttcggata caaacttacg tgactgtgac cgacgtcgtc
    13261 gggtaaaagt acgtgattga tcgtcggaac tgcgcatcaa tattgtcctt gttgaagata
    13321 tgatgctcca tgtacctcgc cttgggctcg acccggtacc gagggagatc cgacactcca
    13381 ttgatcagtg gatgtgaggt cgcgcagtga taacattcat tgtagttctc aatcagaagc
    13441 ttccagttcg cctccacgtc catctcccaa taatggtcaa aagtgtattc cccgtcaaag
    13501 tcaaagtctt gcatccgcgg ctgctcatcg atcttttgga agtcatcctc ccacttgacc
    13561 tccgggtccc cggcttctag attcacccag acgaagcccg ctttatcaat atgtacatgg
    13621 attgggagga gtccgtgctg acttttgtcg aagtttgata cagtctcgaa gcgaggtgcc
    13681 ttcgataggt tgcccttcag tccgtaggac cagccatgat atttgcagct gaggatcgag
    13741 gtggccccag accgagcttg gacaactggg tatgcgcgat gtcgacaaat gttgtgaaat
    13801 ccattgatgc taccttcgcg gtcccgagtt agaaagaagg agaaattgga gatggtaaag
    13861 gaaaggaagt cgccgggttt ggttagtcgg ctagaatgtg tgagtagcat ccaacgcttg
    13921 gagaagatgg ctcgtcgctc cagctgatac atggcatcgg agcgatacca tgaccccgga
    13981 aggctccgag gcggagagct tttctcggaa gtgttggatg accggccaag tagtcgccac
    14041 atgctgtcgg acgagagaaa attgttcggg cagctcggag gagctctgat tgtcgctgtt
    14101 tctatataat ggagaagtgc tggtaagtgg ggtctcggct tcggcgttgc agcatcagag
    14161 atgggggcgt tgggagctcg tccgaggaca ccactgataa gccattggat aaggatcatc
    14221 ggcttatcta tcatatcttt ctgctgccac gatggctgtc aaccaactga gagaaacgat
    14281 agaataacat gggtgcttat cctgtttcac ttgctagtcg ctgctgcata tcgccacatt
    14341 gggccacaga cgggattttt cgatacaatt caaacaatca accatgtcta tctttggtga
    14401 gtgccaaagg gtcctgtcta tattatgcta tttattacat gtataagtcg ttcaagtcat
    14461 ttttatgcga ctcacatcgt cctgtcccaa cgaccagagt cttctcttct cttctttttc
    14521 cggctggcgg gatagccacc aactcaactc atattttgct cgtattccgc attttcctga
    14581 gcaagaacgt cgctgctccg atcaaaactg accctaatat cccacagcaa gcaccaaaaa
    14641 gctgcaaccc tgagtaatcc gtgtaatttt gcttttcgag tatggctccc atgatcggca
    14701 acccggtcag gcagctgcca aagttagcaa ccggtaaatt tgacttgctt aaaggtctga
    14761 tactcacctt actgacatga ttagctgaaa tgttccaaat cgctgaccca gggtttgcag
    14821 atctcccact ttggcaacac atggcatcat aagggagaca accgcgccac tgacgaagcc
    14881 atagaccgcc gagaagacga taatgcccgc atgtgaaggg tggtagttga aaggaagcca
    14941 aagacagagc attgacactc cagtaccgaa gcagcagagt gtcaggacgt tgaagtgacc
    15001 aaacacgtct gctagctgag gagggatgag acgtccgaag atggaggcgg cactgaagtc
    15061 cacaggagtc agccatcata gatgcgagga aaggttttgc gcaaccttac ttgatgatag
    15121 aaatcaggta gagagcaaga gtcgacgaaa atcccgcgtt ctctgccatg ctggaaatat
    15181 agtcgaaagg ggcccagaga ccccacctgt cactgtcagt ggatgggtaa ggccattgat
    15241 aggaacgaat gacgaacatg atgaaaaatg cgccagcggt gtacaatcca aatgcggtat
    15301 ccttcagcag agtcaggtcg acccacgctg ctttaccgtt ccactctttg cgcggaagac
    15361 ggctgcggat cagtaggcag gctattgcca gcataattcc gacgaatagc gctgtatacc
    15421 gaacggcacc atagaagccg atgtcattga tgacccggtc aaggaatatg ggaaagataa
    15481 cacccccaag tgaacttccc gataccgcaa tgccagttgc aaggcctcgg cggcgaacga
    15541 accattggcc gacgcaaatc atggccgaag tgaaaacacc accggctccg atgccgaagc
    15601 agaggccttg cgcaaggaat atttgatagt actcgtgcgc caggctagtc atacaaagtc
    15661 ctagcacaca gagaatgctg catggccaga ggaccgggat cgggccataa gtgtcaatca
    15721 tgcggcccca tagcggtccc ggcgcccaca tgagggccag ctgcacggcg aaaatccatg
    15781 atatgtcgga cgcgtcgtaa tctttgagcg acgtctgttg atatgttgtt tggaagactc
    15841 cgatactgtg ataaggtcag tatgaagtag gtgggcaaat tcacccaggc tatacatacg
    15901 cattcaggaa cccaaaggag gagaataggg cgcaaaagct tccggccacc gtcagccagc
    15961 ccttgacccc ttcttcgggc gggatggttg gctcctctac cggctggttc ttaggctcag
    16021 acatggtttg tcttgcccag aactctcaag cagatattcc ctccaatata tgtagagccc
    16081 ttgtcaaata tttgaagatg catgaagcga atgacaaatt ctggagggaa aagcctccac
    16141 agggtccctc cggacagcga ttcggtctac gactggctaa gtccgaccga ataaaagcgg
    16201 gcgctaagat aagtatctgg gtttcgatga gaagcttcgc ctcggaccct cggctctcgt
    16261 tatgtccgat ggggcgaaca cgacaaggat ttggctcacc agggtcgcgc taattatgcg
    16321 aacgcttgtc gctttgggca tgaaattgac cgtgtcatcg cagtggcaga atgccatctg
    16381 acccgttcaa tcttcaataa aagaaaatac atatgctgtg gacattggtc ggacgatgag
    16441 ctggagccaa atgacagcaa ccaggagcat tcaactggta gtcttttttc ttccgctcgc
    16501 gacctgctgg atcccacaaa gcggctgcga gcaagctaca ccagggaacc ctggccggag
    16561 gactctcgaa cccattattg ggatgatgcc ggcccacatg gctccactgt gctgaactac
    16621 cgcaggatac ctaaactctg atgccaactg ccggatcaat gtacagggca gcggacttca
    16681 tggactacgg caggctgcgc cggacattgg gacgtgttca tgcgacactt gattcatatc
    16741 gacagcgggc aatatgattc gctaatatac ccttcacggc cagtcctcag tttggcctag
    16801 atttacaatt ccgtccgcac taaagaatgc agaccgagta ttgacttggg catcagttct
    16861 gctcaggtca tagcacaaat gcttctgatc ggagaatttc ggatgtatcc gaaacatctg
    16921 cttgcggctg cacaccgaca tgaaaaaggc acgtctcatt catcggaata ttccccgtct
    16981 caaagttggt gacgtgaacg gcacattaac cccaccaatc agacgccagg gaggcctgat
    17041 gctagcccga tgatcgtcaa gcgagttccc tggacgatgc cgtcctcccc gatggaacag
    17101 ccattatcca tctgctggat gggaatacta gcccgttgaa ccgagctact tcaggaacag
    17161 atgttcaagt gtgaccttcc cgtctttaag tagtatagct tcacaattgg gggttaaggc
    17221 tgcttgtgtc ccttgtaagt gaccgacatc agcaatggcc gttatgacga ccctccggta
    17281 tttggtcgca tacgaggtgc agtagtacag catattagac caaaagcctc cagggtgctt
    17341 gcattgggat gaacatcgtc caggatcacc tccggcggta tccagcaggt gttcagccga
    17401 atagccccgt ggctgtattt ggcagggagt atccttgtcg gtttgcatat aggtagctgt
    17461 ctagaacttg tgagttcgag ctgcgcagtt atatgggtga tcgttttcca agtggcatgc
    17521 tagcgacgtg gctggaataa gctatggtca ccaggcctca tagcacattg ctccttcgta
    17581 atgcggcaat tcaattccta tataaccttt ctaaagccct cgctacgatc agaaataagc
    17641 aggccgtgat tgaattctgg tagtagacct tatgcgaccg cgcgaaatta gtaaccgaat
    17701 cattgatgga ttgactgcga gatggagatt ccagtatcat tcctacaacc atgctcaagc
    17761 tgggaaaagc tgtgaatgaa caattagcag aagataggcc gtgatcaagc cttgagatgc
    17821 aatgaatagc aaaaatgttt caatacctgc tatcacaatc tttgcagaca gattgttact
    17881 agggtggaag gatatctagt tctttgggaa caacacactt tgcctgatac atatcttctg
    17941 gagatttcat tgttcttctg gaaaatgatc agggcaggac tttcatcctc ttatagtaca
    18001 tcatctccca ataaactaat ggtgggaccg aggccagccc ggggcatata accgacccca
    18061 gagagcccgc gaccccacgg tcggcgacgt tctccggtcg acgatggcct caaaaaccgg
    18121 ggtcatcccc cacgaaaata tccccaattc acaaccagca ccatgcctaa cacccgtccc
    18181 cttgtccgtg cggcatgcca taatctctcc ggcatgcgcc atgcttctac tagcgccacg
    18241 aaaaaggctg gccccctcgc cggcatcact gtcgtcagtc tggaacaagc catagccgct
    18301 cccttctgta cccgccaact agccgaccta ggagcccgag tcatcaaagt cgaacgacct
    18361 ggcgtcggag actttgctcg caattatgac acccgcgtta acggcctagc ctcccacttc
    18421 gtctggacca accggtctaa agagagtctc gccttggacc tcaaaaagcc gtccgatcac
    18481 agcgtgctca tgcgcctgct cggccgcgcc gatgtcctcg tccagaacct cgctcccggc
    18541 gccagtgctc gactgggttt atcctacgat gatctcaaag cggctcatcc atccttgatt
    18601 gtgtgcaaca tctccgggta tggtcctgac ggaccgtacc gcgataagaa ggcctacgat
    18661 ctgttgatcc agagcgaggc tggcatgctc tccgtcacgg ggacgggaaa agagcccgcc
    18721 aaggtgggca tctccatcgc tgatatttcc gctggtagct atgcctactc caatatcctg
    18781 gcggcgttgt atcagcggga gagggatccc tcgaagcggg ggtgtaacat tgatatctcc
    18841 atgttggaga gcatggttga gtggatgggc ttccctatgt attatactta tgagaatgcc
    18901 ccgggcccga caccagcggg tgcttcgcat gcggctatct atccttatgg cccgtttgag
    18961 acgggagatg gaacggtgat gttggggatc cagaatgagc gtgagtgggc taagttctgt
    19021 gacatcgtct tgggtcaacc cagtcttgct acgaatgagc ggtttgtgaa taactcgctg
    19081 cgctcgcaga accgtgatga gttgaagaag ataatctgtg acgtcttctc gtcgctttcg
    19141 gcggagcagg tgattgctcg actggatgca gcggcgattg ctaatgccag cgtcaatgat
    19201 atgcaaggcg tctggaacca cccacagctc aaggctcggc agcgatggac agatgttaag
    19261 acgcccgcag gaagtgtgcc ggctctgcta cctcctggaa tgaccatggg ggatgaggat
    19321 acttatgggg cgcgcatgga cgctgtccct gatgtgggtg agcataacaa ggctattctg
    19381 gccgagttgg ggctcgacga gggtacggag aaatagctgc agttgaatta atgacatgta
    19441 cagttgagct agtggacttg gctatccttg cgagtattgg aacttttagg ccctttgtaa
    19501 ataactcagt gcgatggatt cacctcgggc aattctactg tccactcacg aggttgaaga
    19561 tacctgcatg tcaaaggatg ttcagacgta gaactagtcg accacaatat ggatcttaca
    19621 gtttaatcca attcaggcaa cctacccctg ctgcccctaa tatcaccccg cgacggtatc
    19681 cagcgtaaag tgaatatcgg cgcaatatac ccatcgccga agcaagtgga tcgggaaaac
    19741 aggcaaaaag ccgacatgcc cgccaagacc gaggcagcat aaagccgctt tatcctcgac
    19801 tacggctact tgcattctgc ctggccacct ctgaactcca ctgtggacga tctctttcat
    19861 tggtaattgg agctaattcg aggatcatgt ccagtcagga gtcatcgggc caccgacagg
    19921 taagaaccag ggccaagcag gcttgtctcc actgcaataa gcggcgaatc cgctgcaatg
    19981 tgctacagat gcgcccatgc cagaattgtc tggcattgaa tgtaccctgt gagataggcg
    20041 tttcaaagcg aggaaagtat gttttcacgg tttcgtcatt atggtagttt ggcgtagact
    20101 gattcaatgg cttaggtatc cccgtaagaa gagtgctcgg caacaaaccg acggcaactc
    20161 ggtccaattg ccggcatcat ctgcgaaggg agggaaccat tcattcaccg tgtcagcagg
    20221 tgataaatcc gacgcaaaag agtcgcatgt tcacccgata ccaggggatg ctgcgagtgc
    20281 gcatccaaca gtgttctttg gtgaatcgag tccactcact gtagtgattg acgaagggcg
    20341 ccggtcgcct gaaaagggaa ctaatgagat gcatatgact cgctttcatt atgccattcc
    20401 tgagaaactt gatgccttca acacccgtga tgaggctttc cgagcacaca agatcaagca
    20461 ggaaggccag ctgagagctg atggggcctt ctcgtacccg ccgccagaga catgcgaaac
    20521 tcttctgcgg gcgtactttg actggtttca cccctgtttc ccaatccttg attgtgctgc
    20581 ggtgtatgag agctatgtgc aggggagcat gtcgcccctc ttactccagg cgatactgtt
    20641 cataggcgtc agcctttgca cggatgaggt gtttgcccgg acggagtttt ctgttcggta
    20701 ctgggccaag tttctctttt acagccgagc aaaggcaatc tacgatgctg aatgggagtc
    20761 taacaagacg gtcaagattc aagcgctgtt tttgttgagc ttctggcgtg gaggaccatc
    20821 tgaggagcgg gacattcgat tctggcttgg cattgccatt gacctggcac aaaagcgcgg
    20881 catgcatttg atgtatgtat tcttttgtct taccctgtct cctgttaact cagtcaggtc
    20941 caaattcccg tttgcctccc gtcgagaggc aggtctatgg aagcggattt ggtggtcgct
    21001 ttacgtatgt cacctctcgt aagcctgatg tagatgctga ccgttgctag acccgagacc
    21061 agcaaagcgc cgcagcactt gggcttccgc cacacattcg ggacgaagac tgcgatgtcg
    21121 acatgctaga gcctgaggat atccgagagg aggctgtggg cggccaaagt cattttgggg
    21181 tgcagtgtat cgaagacctc tcttatccag ccgaaatggc aaagttagcc aaattatgta
    21241 tgtccgaacc tccatactgc gaatctttgc tcactgttca gtgcgttcta ttgtctcgac
    21301 ccagtactcg ccgctgggtc cgtcatctaa cggtgcgtca cgagcggcat tgcaccagca
    21361 actgagggac tgggaagcca atatgcctct tgagctgaag ctggaaaatg ccacaactcc
    21421 acgagccaag tttctggccg gactcttaca tatgacatac cagtaggtgg catgtattgg
    21481 gtacttgagt gtatttcact gattgaatgc cattagaaat ctctacatcc tgctttaccg
    21541 accgtccttt cttcaccctc ctgatggaga tctggatagt caaggtcaga tagccttgaa
    21601 tgccgcgacg aaaagtacac gagtgttgga ggatatgctt tcgcataact tggtccaaca
    21661 cggctcttct catctgtaag accgtccccg ccgatatgct atagaggatt caagctgacc
    21721 atgtagaatc atacacgtgt ttttaaccct ctgcatccac accattcatt tccgtcgcac
    21781 gtccgggaca ggtcgtaaat tggcggaaca ccgagcccgg ctctgtctct tgagcctaca
    21841 agagctgcaa aaatcttggg acttggagaa ctgggtacta aacctgttct tctgatgttt
    21901 ggacgatcgc acggcccgca ctctgcgacc ggtcgatccc actgttccct ccccaaaact
    21961 cgagagccgt gatcttgtct ccgccacccc ggatgttttc ccttctctca atataat
//
