LOCUS       KZ851954.1             22317 bp    DNA     linear   PLN 20-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   KZ851954
VERSION     KZ851954.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 07:38:58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 28347
            Orig. end    :: 50664
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22317
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[38347:39018](+), [39078:40524](+),
                     [40573:40664](+)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(10001..10671,10732..12177,12227..12317)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..22317
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22317
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            join(4646..5166,5225..5945,6025..6517)
                     /locus_tag="M747DRAFT_269005"
                     /product="hypothetical protein"
     gene            4646..6517
                     /locus_tag="M747DRAFT_269005"
     CDS             join(5127..5166,5225..5945,6025..6145)
                     /codon_start=1
                     /db_xref="InterPro:IPR007062"
                     /db_xref="PFAM:PF04979"
                     /locus_tag="M747DRAFT_269005"
                     /note="GO_function: GO:0004864 - protein phosphatase
                     inhibitor activity [Evidence IEA]; GO_process: GO:0043666 -
                     regulation of phosphoprotein phosphatase activity [Evidence
                     IEA]; GO_process: GO:0009966 - regulation of signal
                     transduction [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_269005-T1"
                     /transl_table=1
                     /translation="MSHHMEDAHKRPKGILKNSSSQVPQVAQHAHATLTIPSTSADPTD
                     TKELTLQNTLQNAGRRRSSSNTRPGSSSRRQSLASIHGHHDDSSPRLKWDEANLYLTEQ
                     EKTAKMKIDEPKTPYAPRYDPAEDEDELAGEESLIDAQDIVVDELDKTKKAPKKTVAED
                     DIPELELGEAEEYGGDAHMGDADRIVRERSLSNDSHRGGKHVVVGAGELNGETESGGDT
                     LMTAGEAEEKHRQFEQHRKKHYEMRNIKDLLAHPEDLEDEMDEDEDEGDSSSAAVPPPM
                     PRIPERFLNGGK"
     mRNA            join(<7880..8643,8707..>9376)
                     /gene="SFH5"
                     /locus_tag="M747DRAFT_318961"
                     /product="Non-classical phosphatidylinositol transfer
                     protein (PITP)"
     gene            <7880..>9376
                     /gene="SFH5"
                     /locus_tag="M747DRAFT_318961"
     CDS             join(<7880..8643,8707..>9376)
                     /codon_start=1
                     /db_xref="InterPro:IPR001251"
                     /db_xref="InterPro:IPR011074"
                     /db_xref="InterPro:IPR036273"
                     /db_xref="InterPro:IPR036865"
                     /db_xref="PFAM:PF00650"
                     /db_xref="PFAM:PF03765"
                     /gene="SFH5"
                     /locus_tag="M747DRAFT_318961"
                     /product="Non-classical phosphatidylinositol transfer
                     protein (PITP)"
                     /protein_id="ncbi_M747DRAFT_318961-T1"
                     /transl_table=1
                     /translation="MADQPEKTAAAPAAPEAQPPTTATTTTEPAVSESQTQPEPQPEAE
                     QKVEQATTGEEASPAPAATEPPVTEPTPAPAQEAPEDKKEEAPKEETKETKAEESKEEQ
                     KAEEPAAEPKAEAAKEEEQKPAQPEYLAKNPALSQFFDRLSAILSSTGHNEMWGVTLKD
                     SSDVPTVNILIKFLRANEGNVKLAEEQLTKALQWRKEMNPLALTEGRYSAERYGGLGYV
                     TKYPEANGKETIVTWNVYGNVKSIDQTFGDVDGFIKWRVALMELAVKDLKLSEATTVID
                     YDGEDPYQMLQVHDYQNVSFLRLNPTIKAASKKTIEVFSMAYPELLREKFFVNVPAIMG
                     WMFAAMKVFLSKNTTRKFHPISNGANLAREFPSLKDKFPKTYGGNGATLEEDAFTVNLE
                     KAEPAPEAPKEEPKEESKQEQAEAPKEEAKAEQAEAPKEEVKEEAKEEAKTEQPAAEEP
                     AKAEAAVTTQEAPAAAEAK"
     mRNA            join(9952..10671,10732..12177,12227..12385)
                     /locus_tag="M747DRAFT_289311"
                     /product="terpene synthase"
     gene            9952..12385
                     /locus_tag="M747DRAFT_289311"
     CDS             join(10001..10671,10732..12177,12227..12317)
                     /codon_start=1
                     /db_xref="InterPro:IPR002365"
                     /db_xref="InterPro:IPR008930"
                     /db_xref="InterPro:IPR018333"
                     /db_xref="InterPro:IPR032696"
                     /db_xref="InterPro:IPR032697"
                     /db_xref="PFAM:PF00432"
                     /db_xref="PFAM:PF13243"
                     /db_xref="PFAM:PF13249"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: terpene_cyclase"
                     /gene_kind="biosynthetic"
                     /locus_tag="M747DRAFT_289311"
                     /note="BUSCO:EOG09260SIZ; GO_component: GO:0005811 - lipid
                     droplet [Evidence IEA]; GO_function: GO:0000250 -
                     lanosterol synthase activity [Evidence IEA]; GO_function:
                     GO:0042300 - beta-amyrin synthase activity [Evidence IEA];
                     GO_function: GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]; GO_process: GO:0016104 -
                     triterpenoid biosynthetic process [Evidence IEA]"
                     /product="terpene synthase"
                     /protein_id="ncbi_M747DRAFT_289311-T1"
                     /sec_met_domain="terpene_cyclase (E-value: 1.6e-16,
                     bitscore: 52.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MSGSHIGPWRTPAQGHLTPDANGDLKTDYTRWRLRDDRGRQTWHY
                     LESDAENEQWPQSIADKYFLGLPTGLPELPKPQTPLQCAENGLEFFSKLQLEPGNWACE
                     YGGPMFLLPVLIITYYVTKTPIPPEYATEIKRYLFARQHPEDGGWGLHIEAHSSVFGTC
                     MNYVTLRLIGVSEDDPRMIKARGLLHQFGGAIYGPHWAKFSLAVLGVMDWECVNPVPPE
                     IWLLPDWVPFAPWRWWIHIRQVFLPMSYLWSKRFSHPLDPLTKQLRQELYTQPYDSIDF
                     AAHRNSIHKADNYYPKTWLLNTLNSLLVNIWNPYLRVPAIVRRAEEWTWELVRMEDENT
                     DYAGLGPVSNPFNMIVCYEHDGPDSYSVRRHRERLHDYMWMKDEGMLMNGTNGVQVWDT
                     AFITQSIVVAGFGDDPKWRPMLTKALEFLEDHQLRENVPDQEKCYRQHRKGAWPFSNKT
                     QGYTVSDCTAEGLRSTIQLQEMHNFPKLISEERLKDSVDCLLLMQNPTGGFTEYETTRA
                     SEKVEWLNAAEVFGGIMIGYDYPECTTASVTALSLFSKYYPNYRAAEIKSAKEKAVQYI
                     KRVQRADGSWYGSWGICFTYAAMFALESLASIGETYETSADSRRGCEFLISKQKEDGGW
                     GESYLSSEKHVYVQHEKSQVVQTAWASLALMEAGYPHKEPLRKAMQLLMSRQQANGEWL
                     QESIEGVFNQSCMISYPNYKLYWPIRALGLYARKFGNEELV"
     mRNA            join(12520..13527,13583..14423)
                     /locus_tag="M747DRAFT_299726"
                     /product="CS-domain-containing protein"
     gene            12520..14423
                     /locus_tag="M747DRAFT_299726"
     CDS             join(12730..13527,13583..14173)
                     /codon_start=1
                     /db_xref="InterPro:IPR007052"
                     /db_xref="InterPro:IPR007699"
                     /db_xref="InterPro:IPR008978"
                     /db_xref="InterPro:IPR011990"
                     /db_xref="PFAM:PF04969"
                     /db_xref="PFAM:PF05002"
                     /locus_tag="M747DRAFT_299726"
                     /note="BUSCO:EOG09264LH2; GO_function: GO:0005515 - protein
                     binding [Evidence IEA]"
                     /product="CS-domain-containing protein"
                     /protein_id="ncbi_M747DRAFT_299726-T1"
                     /transl_table=1
                     /translation="MNAASLGDTALQQSDPHTATIHYTTALLTHPRSPSYFIKRSTAFS
                     RLKPTPNLSAALRDAESAVLLARERGKRELIVEAQMRRAIVLFLMGRYVAAEGVVGVVE
                     GMIGLDKDGNGGEDKEEKVRKAMGGGAGKGIEAEVRIWGAKIRAKVNGLGEQSGERGEK
                     VEEVPVGVKVPGEKELRGQLEELRGGKVGEGIGGEEKQSQKVEDKVEEKERAEVKETQQ
                     QQQQQQQQVKVRHEWYQSGETVVVTLYVKGVPKDKVAIELKEDSTSIQFPLPSGAEYDF
                     TLDPLFAPIDPSTSKVSVFSTKIEISLRKKTPGQKWSALESTTGPVISTPQPTVTPTTT
                     TTQAQAPSYPTSSRHGAKDWDKLASSLTQKSKKDKTKSSSKPKDEQGEGEEDDGEASDA
                     ESINSDFGGGDAVDGFFKKLYANADPDTRRAMVKSYVESQGTSLSTNWDEVGQGPVKVR
                     PPSE"
     mRNA            complement(join(14521..15841,15899..16178))
                     /locus_tag="M747DRAFT_326368"
                     /product="PQ loop repeat protein"
     gene            complement(14521..16178)
                     /locus_tag="M747DRAFT_326368"
     CDS             complement(join(14740..15841,15899..15954))
                     /codon_start=1
                     /db_xref="InterPro:IPR006603"
                     /db_xref="PFAM:PF04193"
                     /locus_tag="M747DRAFT_326368"
                     /note="EggNog:ENOG41"
                     /product="PQ loop repeat protein"
                     /protein_id="ncbi_M747DRAFT_326368-T1"
                     /transl_table=1
                     /translation="MFPAVTGNIDLEALSGICGSISIACWVVVFSPQIIENFRRGSADG
                     LSLLFLIVWLAGDVFNILGAVLQGVLPTMIILAVYYTLADVVLLAQCFYYRGFTLRDEP
                     SSPPRPVSPITAETYDEDTEIPSPVVPRKPTERTALLTSKQRSASYQAPLDTRSPASSA
                     TITPHHQPLLAHRRHSASSFLHTTVDGTHLSPVTPLVEPAKQPRPPRTLTLLQATFFNG
                     SAIILVCAAGILGWYISQTSSLSSDKNNNNKHKDSPDDLKMDTLGQVFGYLCAVLYLGS
                     RLPQILLNYRRKSTDGVSLLFFLFACIGNLTYVLSILAYSPVCERSHHGRCRSDELASL
                     YGRYILVNLSWLIGSFGTLLLDMCIFIQFFLYQDANGGEVDAEAR"
     mRNA            <16458..>17612
                     /locus_tag="M747DRAFT_248061"
                     /product="sir2 family transcriptional regulator"
     gene            <16458..>17612
                     /locus_tag="M747DRAFT_248061"
     CDS             <16458..>17612
                     /codon_start=1
                     /db_xref="InterPro:IPR003000"
                     /db_xref="InterPro:IPR026590"
                     /db_xref="InterPro:IPR029035"
                     /db_xref="PFAM:PF02146"
                     /locus_tag="M747DRAFT_248061"
                     /note="EggNog:ENOG41; GO_function: GO:0070403 - NAD+
                     binding [Evidence IEA]"
                     /product="sir2 family transcriptional regulator"
                     /protein_id="ncbi_M747DRAFT_248061-T1"
                     /transl_table=1
                     /translation="MTAPAIRIPFTGPLPPPIIVPPSARTVAGAIDALLAFLTAPPSPY
                     LRGVDVGRHSQTVLLTGAGISVASGLSDYRGENGTYITNKTYRPIYYHEFVARHEFRKR
                     YWARSFIGWPGLLKAKPNSTHWAIKDIGTKGYISSVVTQNVDSFHSVAHPELPTLELHG
                     YLRSAVCINCRTQVPRDEFQQSLERLNPAWAEFLKKMVDIGALNADNPEEQRRRGLKIN
                     PDGDVDLPEAPYSTFRYPACPTCLEKPPRLQDGSQSRVEVERDGAWLPSSTAGILKPAV
                     IMFGENIDPAVRLGAEEAIDDAGRLLVLGSSLATYSAWRLVERAYKRGMPIGIINIGGV
                     RNESILFSKAEQETEAVCRHVRCSLPSQDILGPVAAQLPSLTHH"
     mRNA            join(17950..18201,18284..18307,18375..19557)
                     /gene="PHO85_1"
                     /locus_tag="M747DRAFT_299728"
                     /product="negative regulator of the PHO system"
     gene            17950..19557
                     /gene="PHO85_1"
                     /locus_tag="M747DRAFT_299728"
     CDS             join(17977..18201,18284..18307,18375..19289)
                     /codon_start=1
                     /db_xref="InterPro:IPR000719"
                     /db_xref="InterPro:IPR008271"
                     /db_xref="InterPro:IPR011009"
                     /db_xref="InterPro:IPR017441"
                     /db_xref="PFAM:PF00069"
                     /db_xref="PFAM:PF07714"
                     /gene="PHO85_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 171.7;
                     E-value: 3.5e-52)"
                     /gene_kind="regulatory"
                     /locus_tag="M747DRAFT_299728"
                     /note="GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA]; GO_function: GO:0005524 - ATP binding
                     [Evidence IEA]; GO_process: GO:0006468 - protein
                     phosphorylation [Evidence IEA]"
                     /product="negative regulator of the PHO system"
                     /protein_id="ncbi_M747DRAFT_299728-T1"
                     /sec_met_domain="Pkinase (E-value: 1.4e-77, bitscore:
                     252.5, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MDMDGRDRSKSRTLQPPTADYLDLISNLASPKTFLFHHPRSTSRS
                     HPTPAAQSTTVAPSTTMDKQQPSSFQQLEKLGEGTYATVFKGRNRQTGELVALKEIHLD
                     SEEGTPSTAIREISLMKELKHESIVSLYDVIHTENKLMLVFEYMDKDLKKYMDTRADRG
                     QLDQATIMSFMHQLLKGIAFCHENRVLHRDLKPQNLLINKKGQLKLGDFGLARAFGIPV
                     NTFSNEVVTLWYRAPDVLLGSRTYNTSIDIWSAGCIMAELYTGRPLFPGTTNEDQLIKI
                     FRLMGTPSERSWPGISQLPEYKPNFHVYATQDLSLILPQIDPLGLDLLSRMLQLRPEMR
                     ISAQDALHHPWFRDLPQLQAQLQQQQQQQQQQMAGAYGGMVPPQQTY"
     mRNA            join(<20077..20453,20555..>20849)
                     /locus_tag="M747DRAFT_346557"
                     /product="Nnf1-domain-containing protein"
     gene            <20077..>20849
                     /locus_tag="M747DRAFT_346557"
     CDS             join(<20077..20453,20555..>20849)
                     /codon_start=1
                     /db_xref="InterPro:IPR007128"
                     /db_xref="PFAM:PF03980"
                     /locus_tag="M747DRAFT_346557"
                     /note="GO_component: GO:0000818 - nuclear MIS12/MIND
                     complex [Evidence IEA]"
                     /product="Nnf1-domain-containing protein"
                     /protein_id="ncbi_M747DRAFT_346557-T1"
                     /transl_table=1
                     /translation="MSTEPNPSAQRPGASPSPPPPAPVPLTPGPRASKLQEIFDKALAR
                     TLRANSYANFSGCFPTPAKHVPASLESVWRQLNAKLEESAKAEFEDILAERDAVRQLNE
                     LDRLVGEAKVRKDRGVGGDSVAPHTLSPEELYKAHLLPHLMETQADLDAKINSVQNQNA
                     ELAEKVQAQRSEIESLLSGLEAVVADLEGAAAATTQFTSEHQLRQEAAQMDGEVKARSE
                     I"
ORIGIN
        1 gcctcccgac cccttgaaga ccgatgtggc cgaggagttc ttcgcttctg cagtagatgc
       61 attgttccag cttctggatg acccagatgg agggcttccg catgcggtga tgcaattaag
      121 cagtgctgtt ctacagaaac tcgagcgtca ggacggtcgt gaacggttcc ttgagttctt
      181 gttcgtccag tggttctttg caaagttcct ctatagcgca ctgacctacc ctgaggtatg
      241 agaaggctcg cccagatgtt ttcaaagttc ctattctaac accatgtcca ggcccacggt
      301 ctcttgcttg acttccatat cagaaaagat gctagagaga aactcctcgg acaggtcgga
      361 ctccgtgcct actcgcaagt ctttgctgtc cttcattcca tgtccgttgt ccctgcatcc
      421 ggccactaca tgaagcctta taaacgagcc atcgctaatc caaacatgca ggaaccacta
      481 ttctatggct cgtcccacgg tgagaaggca cgtggagagc atgctttgcc ggttcgacca
      541 cgtcgaccca cgcaggaacg tcagcggaac ccagccctct tcccgcgcaa cagctctcaa
      601 caggcgggag tcacctgctg cattcctgat gctctccgct gctgatactc ttgccctgct
      661 gaatgctctt ttcccgagga caagcgcttc tacatgcaat tccccactct catcttccgg
      721 gatgccttcg tcccctgctg gttctttggc tgctcggtca gatcgctcta tagcgtctat
      781 tattgagccg ggatttttcc ggcctccttc tgataacatg tccattcacg ccctccagga
      841 ccagagacta tttgcctctg acatggcctt cctgtcgtta ccagagaatt gcatgagccg
      901 caatgctgac aggatccgct ttgagctgtc agacctgagc gagcccgatg gtcggacaac
      961 tctggaacca cctgcagctg aagaatggac catcttttcc atgacccgaa atggaagatg
     1021 cttaacctgg ggtctattcc ccgatgatgg cccatccagt tttccgggaa acgcctctgt
     1081 ggatgacgtt cagtccacca ccttgggaat ggaagacaat tctgaagctc tccaaacggc
     1141 cattgtgaaa ttgattcagg ataaccctgc cgatgatgct gccgagtatg gttttataga
     1201 tcttcatggc gcatcccaag acgctcatgt atccctaaag caaaagttcg atagggccat
     1261 ggaacattgc caccatgact ctgatttcat cggtgcccac tactggtgga atgccggccg
     1321 acagcttgtc cgcagcgttg caaactcccc atctcgacgc ctggacgact cgtggattct
     1381 cgagcccatg cacgcatcgt gtgtccgctc actcgctacc tcacgggcgg ttatcgaacg
     1441 atgtgaaacg gatcttgtgg ccctcaacag gcatgtgcaa cgggtgcaaa aatccgtaaa
     1501 ggagatgatg gccactgtgg ccaagctccg agacaagatg tggtacatga ctgacgtaaa
     1561 gcactcgatg aggtacgaag atgccaaaca cgtcgcacta gcattgaaga ctatgatcta
     1621 ctctgctcgc ctctacagac aagcaccaag cgatggccgg tctcgcagca gcatgagacc
     1681 gttcggaaat tctcttctcc aaaaaccaga gttgcaagtc atgaatatca tgaaggcacc
     1741 gagcagtcaa ggcggtccca acaagctgtc agatgagcag gtggacctga tccgcaaatg
     1801 gctgtctcac aacaacatcg acaatttctg caaaggtgag gagcgaattc accggttctg
     1861 ctacgaggtg aagacaagta tcaatcggct ggttggcgag accatggccg aaaccccggt
     1921 gctgtggtcc agcgaattgt atcacaaaga gcgagtcatg tacgaaggct ccagtaaccg
     1981 aagcttccta agcctctcct cgagcatgcg gcctttcaat atgtctagtg aagacacgcc
     2041 acatgcctca ccagtgcagg ggaatactac tcgcccatca gacacttcaa ggttcacgca
     2101 ggacctacct ccgctgaact ccaagtcctc tttccagagt ctgatgtccg ataagtggaa
     2161 aattcctcgg gaaccctcga tcacagacgc ctcttcaatc ggcgggtccc cggggagggc
     2221 tgcctcaact actaccggcg attcgtacag cactttctgg tcaacgccac atcagcccgc
     2281 acattatgca ccaagtgctt ccagcctata ttcccggccc ccctctatgt tcagcgataa
     2341 cggtattcag ccgtcacgtc gcaatgatcg caaaacgcac agcaaaggag ctttcttgga
     2401 cggcctgaaa cagaccctga caagcttgct cctaagtgac ttaggctccc cagtgtggag
     2461 ctgtggaagt gagacggacg cttggttcgg aaacgcgctg gagcagaaga gaatccggac
     2521 ccagatgaag aaacgcgcgc gcatccaaca gttctatacc gagtgtgatg agcgaatcgt
     2581 tcatcatacc ctccatcgca caccgtcgga ccgtcggcga agcagatccc tggagtctgc
     2641 agatcgatcc acactcggcg atgccgagac accgtctgca tctgctactg acaattctat
     2701 gcagtcagac gaaacgcagc gcttctcgta cgggtctgtt tttcggcgcc taatagaagt
     2761 cttctcgcga cacgggaacc catttgtcaa gctaaaggca ttgcgggatc tgcgggcgct
     2821 tgttgttgca tctttgaact ccgatagcga cggtacaagc ccattcagtg caattgagca
     2881 gccctcatac ccgcgaggtc gtactcccgg gttccagaac aagagaagcg cccgtcatag
     2941 cttttccgag tctgatgcaa agcgggctca tgcgcaggat tcctctcata caccgacgac
     3001 tcctgcggcc gagtctgtca ttttcgactc ccgaccctcc gactattgtg cacccaccga
     3061 caatcagata gtggatgcac tacgcagcct cctcctcgaa gtgaagccga agacgctatt
     3121 ccgtgacttg cagttcatct cagcctttgt tccttcggag acgttgaaca agactgacag
     3181 cgggactgca tttctacagt ttggcttggc ggctctgagc ctcaaggacg agatctgcaa
     3241 tagcatggtc gaaatcgccg ataatattgt atctcaagaa ttcagccggc gccatccgcc
     3301 cggctacgac catacacccc ggcccgggca cgccctcgag gatgctgcgg gcatgtggat
     3361 aatcactgcc aaagaaggca atccagttgc ccagcgggaa ctggccattc tctacctcac
     3421 ccaccctgaa ctcctcccgc gggtgaccct accactcact ctgttgcgag acacattcaa
     3481 agctgaaatg atgtatcgcc gcgacaagga ttccaagtcc gatccgcaga gcatgtgcct
     3541 ggcactgcac tggatgcagc tgtcggccag tggtggggac gaacttgcac gcaatcgact
     3601 tcgggagcgg gaggagttcg agtctcttgc ataaatctcc ttttctttta cagttctact
     3661 catactcggt cctttcctta ctttcaattc gtttctttct ttcattgctt gcgagcatgt
     3721 gcttgtgatc atctttagga cttatatctt tctcttcttt ttctttttct cttttttcct
     3781 tctcacatct ttctatgact ttgataccaa tcacgacctg ccgatttctg gcatccgacg
     3841 cgggtctact tacgcaacta attttggtgc agacgcgcag atctattgat atcctgtttg
     3901 acagatctgg atggacggtg ttcaccccgg tttccccttg gctgttgtat tttgctatgc
     3961 tactcttctg cgggatatcc ttcgtctttc acggagccgg gcagggtcat gagattcccc
     4021 tatacactta tacctctttt ttgtgcttgg ggcggcattc tgctattcga tcacttgttt
     4081 gtctaccatt ctgttgcttt gctttctatc ttgctggtga gtcgacgcat ctttacaagg
     4141 gggacgaagg gaatcgggct cttggagttc tattgcatac tgggcaagga tgggagtgta
     4201 gaaacgcttt gtagtttgtt agcatctcag accgcagctg gatggacgca gggaaacccg
     4261 gtccaccaga ggggtcagaa tacaagcagc tttatgcaac gttgatgggg tcaggtagtc
     4321 aggtagcaac cacaaccacg tagtgggtcg ggagtcgaca gtcgatcttt cgacaggttt
     4381 gagagtttga gagttggaga tgggacagta ggggaaacag taggaaacag tccagtccct
     4441 cggattgctt gcgacgtcat cggcgggcag ccccacgtgc caggtcactg actgtctgtt
     4501 tgcatttact tcttactgct tcttctcctt ctgtcacttc tgtctcaacc caactggact
     4561 attttctggt cgccttactc tctgacccct tttttttgta cttccttctt ttcccctttc
     4621 ttacccctgc ttgttctggc taagcaaaga aagaaaaaaa aaagaaagtg aaccgagcca
     4681 ccaagtaatc atcagatcca gctggaccgc gcgaacgtga ttcatcatcc gcaaccgtgc
     4741 caccgccctc atttgtcggg ctcatcgtca gaggctgagg aatcccaccc ccgcctcatc
     4801 caggcctcct tcctgtgtgt ctcgtcgcca gctcagcctc agatgctgcc tttcctttcg
     4861 ggcacttgca gctgactgtc attgaatttt ccctttcccc ctgctcattg aatttctttc
     4921 gggtcgcatt tattgcgcat ctgatccgcc ttcttatctt gttatccctt ccctttccgc
     4981 ttttcccctc ttcttttttc tcatacttta ttttccttct gcggcggccg ctgctgttta
     5041 ctttacaaac ctcctacctt atttcccccc atctatacat ctcgactaca cgactacacg
     5101 actcagtttc ggtgcgcttg gcgatcatgt ctcaccatat ggaggatgca cacaagcgac
     5161 ccaagggtaa acaaacctct tgcgatcatc cgcatcctac gcctggttgc taatcggaca
     5221 gcaggtattc tgaagaactc cagctctcag gtgccccagg tcgcgcagca tgctcacgct
     5281 actttgacga tcccttcaac ctcggccgac cctacggaca ccaaggaact tacgcttcag
     5341 aacaccctcc agaatgccgg tcgacgtcgg tcgtcatcca acactcgccc cgggtcttcg
     5401 tcgcgacgac agtctcttgc cagcatccac ggtcatcacg acgactcgtc gccccgcctg
     5461 aagtgggacg aggccaacct gtatttgacg gagcaggaga agacggccaa gatgaagatc
     5521 gatgagccca agacccccta tgcgccgcgc tatgaccccg ccgaggatga ggacgagctg
     5581 gcgggcgagg aaagtctgat tgatgcgcag gatatagtgg tggacgaact ggacaagacg
     5641 aagaaggcgc ccaagaagac ggtcgcagag gacgatattc cggagttgga gctgggagag
     5701 gccgaggagt atggtggtga tgcgcatatg ggagatgccg atcggatcgt gcgcgaacga
     5761 agcttgagca atgactcaca tcggggcggg aagcacgttg tggtcggggc tggcgagctg
     5821 aacggcgaaa ccgagtctgg tggagatacg ttgatgacgg cgggcgaagc cgaggaaaag
     5881 catcgccagt tcgagcagca tcggaagaag cactatgaga tgcggaacat caaggatctc
     5941 cttgcgtaag ttgctcccct attcccagga tggctgtggg atttctcatg gaggtatggt
     6001 atactgacgg gctttgtttt ccagccaccc tgaggatctc gaggacgaaa tggacgaaga
     6061 cgaagatgag ggggacagct caagtgccgc ggtgccgccc ccgatgccta ggatcccgga
     6121 gcgatttcta aatggaggaa agtgagggag cgaaaggaat ggacggacgg gactaagtta
     6181 tcactctact cgagaaggat taggacgaga agaggtgata ggaaaatagg atggagggag
     6241 ggactagttg attcttgctg cataaacgga ctctgtatat tccccagcgt tgtttagtca
     6301 tgatgggacg gacttgtatg aatctatggg aagtactttg ctttttttct tttttttttt
     6361 ttttttcttc ttctctagtt gttcactctt cctgctagct gatgtggatt gtgtcggctc
     6421 ttttttttct ctcatagcga atgatgggtt gcttgatcga ttgatagacg agagagataa
     6481 aaatgaaatg tacggggagg ggagagagtt atggattatt gacacgtctt gtttaaaaac
     6541 tagatacgat gaagtaaatg agctagctgt cagggaaata acccacccga agcagggaga
     6601 gttctagact gtttgtctga ccacagcagg ccagggggga ctcgtcaccc tcggggttat
     6661 atgagtcgcg tcaaaaaata gaatcatcca atactctggg aagtactccg taaaccgaat
     6721 caaaccaaca tagaagataa aaaaaaaaaa aagaaaaaga aaaaaaaaaa aaaaaaatag
     6781 ggaaccaatg ccattagaga aggtgataag tagtcacctt gagtccgcgg ccagactact
     6841 ctgagtaata gtgagttaga gcacgcgcct ctccgctaag cccgaggctg tcaaatcatc
     6901 cgaccacctg agacaagaag aataattata gtatcagaat ccaagagtcg gcatctcaac
     6961 caaccctcga gtcggtgcct tgcatgtcat ctggaggaag tgagtggatg tgatcagtca
     7021 ccgcatgctg taacctgtca ggggcattct gggatttttc ttggtgagtc tgtctgtcgg
     7081 tctctctctc tcctgaaaca tccttgcagg cccactccaa gattcaggag gatgggatgg
     7141 atcattttcg gtttcctagt cgagttgcta ttctgagtaa cttggttagt tagttattct
     7201 actgtactac ggagtactag ctatgtactc tgtgtgtgtg tgtgccttcc ttcacttcca
     7261 ctcaatggat cagatgttga atcaagtata aggtttgtgc tgggttctac tattatctag
     7321 tagtgaagag tcatggtata tgacttttca accatgggat ggatccatat tttaagttgt
     7381 ttgtttggtc tactctggat ctggtctgaa accttccaga tgacagagaa atcgatagat
     7441 aaataaaaca aatcagttag ttgtcttgtc tgatcgccgt tgaaacctcc taattgaaat
     7501 taacggccgc tgcagcaatt aattaattaa tccactgcta tctctgattg gattgcgcgc
     7561 gttttctgtg ctttcttagt ttcgtctttg cctgcttgtc gcttcgcttc gtttctttcg
     7621 cgctttctgt cttttctggt ctctcgtgtt ttcttctctt ctcctcttcc tcttttctct
     7681 tcctctctct ctctctctct ctctctctct ctctcttttt ctcccctgct gttcatttcc
     7741 acggctgtta ttggaaagcc atcccgctcg cgtccgatcg catcacgcaa ttccatacat
     7801 tcattttaat tcttatttcc cctctctcta tctttcacta atctactgct accaaataat
     7861 acatcccact acatccatca tggccgatca gcccgaaaag accgccgccg ctcctgctgc
     7921 ccccgaggcg caacccccca ccaccgccac tactactacc gagcctgcgg tttcggagtc
     7981 tcagactcaa cctgaacctc agccagaagc cgaacaaaaa gtcgagcagg cgacgacagg
     8041 agaagaagca tctcctgccc ccgctgccac ggaacctccc gtgacggaac ccactcccgc
     8101 tcccgcccag gaggcccccg aggataagaa ggaggaagca cccaaggaag agaccaagga
     8161 gaccaaggct gaggaatcca aggaggagca gaaggccgaa gagcccgcgg ctgagcccaa
     8221 ggccgaagca gcaaaggagg aggaacaaaa gcccgctcag cccgagtatc tggccaagaa
     8281 cccggccctg agccagttct tcgatcgtct gtctgccatt ctctcctcca ctggccacaa
     8341 tgagatgtgg ggtgtcaccc tcaaggactc ctcggatgtc cccaccgtca acattctcat
     8401 caagttcctg cgcgccaacg agggtaatgt caagctggcc gaggagcagc tgactaaggc
     8461 cctgcaatgg cgcaaggaga tgaaccccct cgccctgacc gagggccgct acagtgctga
     8521 gcgctatggt ggtctgggct atgtcaccaa gtatcccgag gcgaatggca aggagaccat
     8581 tgttacttgg aacgtctacg gtaatgtcaa gtctattgat cagacctttg gcgatgtaga
     8641 tgggtaagtg ctgctgttgc tgctatttcg gaattgtgaa gagggttaaa tctaactgtc
     8701 gcctaggttc atcaagtggc gtgtcgcgct catggagctc gctgtcaagg acttgaagtt
     8761 gagtgaggcg acgaccgtga tcgactacga cggtgaggac ccgtaccaga tgctccaggt
     8821 ccatgactac cagaacgtca gcttcctccg gctgaacccc accatcaagg cggccagcaa
     8881 gaagaccatc gaggtgttct ccatggccta ccccgagctg ctgcgggaga agttcttcgt
     8941 caacgtgcct gccatcatgg gctggatgtt cgccgccatg aaggtcttcc tcagcaagaa
     9001 caccacccgc aagttccacc ccatctccaa cggtgccaac ctggcccgcg agttcccttc
     9061 cctgaaggac aagttcccca agacctatgg tggtaacggc gcgaccctgg aggaggatgc
     9121 gttcacggtc aacctcgaga aggccgagcc tgccccggag gctcccaagg aggagcctaa
     9181 ggaggagtcc aagcaggagc aggccgaggc tcccaaggaa gaagccaagg cagagcaggc
     9241 tgaggctccc aaggaagagg taaaggagga ggccaaggag gaagccaaga cagagcagcc
     9301 ggcggccgag gagccggcca aggcagaggc tgcagtgacg acccaggagg cgcccgccgc
     9361 agcggaagcc aaataaaaag ctagcaagag gcgtaattca cacctggtcg gaatgaggcc
     9421 aggatcacat aatttacggt aatggatggg acaggttgga ttgatacccg ggggaatcgg
     9481 tagaatgatt ccgtgtcgtt ttgcgtactt gatacctctc gatagtgtgt gctttatatg
     9541 ttctgggatt gatgatagag tgcagaaaca ctagatagta atatttaatg taacaggtca
     9601 tatagccgct gatttaacgt tacgatcttt ctctcgcgtc gaccgttatt ccatgcgttc
     9661 ctgcatgcag cagtaaacta taacactgga tttcctgctc tctttatgct gatctccagc
     9721 caggcacccc tgatgactca gcagccagtg tccctcagtt tcctgcacca acaaaaacac
     9781 caactgcaca gctgctgcac gaacaacagg cagcaaataa aatccgggca agggagatta
     9841 gtgtgttgtt cttcctttct ctcctctcga gtgtggttgt atcctataag ctatccctcc
     9901 cactatccct ctctccacta atctcaaccc tgccattcca ccctttcaat tccccccccc
     9961 cccccccaat accataagtg tacaacaacc ccccatcaca atgtcgggat ctcacatcgg
    10021 cccgtggaga actcccgccc aaggccatct cacccccgac gccaacggcg atctcaaaac
    10081 tgactatacg cgctggcgcc tccgcgacga ccgcggccgc caaacctggc actacctgga
    10141 atccgacgca gagaacgagc aatggcctca atccatcgca gataagtact tcttgggtct
    10201 ccccacggga cttcccgagc tccccaaacc ccagacgcct ctgcaatgcg ccgagaacgg
    10261 gctggagttc ttctccaagt tgcagctgga gccgggaaat tgggcgtgcg agtatggcgg
    10321 gcccatgttc ttgctgcctg tcttgattat cacgtactat gttactaaga cgcctattcc
    10381 gccggagtat gccaccgaga ttaagcggta tttgtttgct aggcagcatc ctgaggatgg
    10441 cggctggggg ttgcatattg aagctcacag ttctgtgttt ggtacttgta tgaattatgt
    10501 tacgttgagg ttaatcggtg tgagcgagga tgatcctagg atgatcaagg ccagggggtt
    10561 gttgcatcaa tttggaggtg ccatctatgg gccccattgg gcgaaattct cgctggctgt
    10621 cttgggtgtg atggattggg agtgtgtgaa tccggtgccg ccggagattt ggtacgtttg
    10681 tttctatcat gtctagtggg tgatttgtgg atgggatact gattcgacca ggctacttcc
    10741 tgactgggtg ccgtttgcgc cctggcgctg gtggattcat attcgccagg tctttctgcc
    10801 catgtcgtat ctgtggtcta agaggttctc gcatcccttg gaccctctca ccaagcagct
    10861 gcggcaggag ctgtataccc agccgtatga ctcgattgac tttgcggcgc atcgcaactc
    10921 aattcacaag gcagacaatt actaccccaa gacttggctg ctgaatacct tgaactctct
    10981 gctcgtcaac atctggaacc cctaccttcg tgtccctgcc attgtgcgtc gcgcggagga
    11041 gtggacgtgg gagttggtcc gcatggagga cgagaatacc gactacgctg gcctggggcc
    11101 tgtgagcaac ccgttcaaca tgattgtgtg ctacgaacat gacggtccgg acagctactc
    11161 ggtccgtcgc catcgcgaac ggctgcacga ctacatgtgg atgaaggacg agggcatgct
    11221 gatgaacggc accaacggcg tccaggtatg ggatacggcc tttatcacgc agagtatcgt
    11281 ggtggccggg ttcggcgatg acccgaaatg gcggcccatg ctcaccaagg cactggagtt
    11341 cctggaagac catcagctgc gcgagaacgt gccggaccag gagaagtgct accgccagca
    11401 ccgcaagggc gcatggccat tcagcaacaa gacgcaggga tacacggtca gcgactgcac
    11461 cgccgaggga ctgcgctcga ccatccagct gcaggagatg cacaacttcc cgaaactgat
    11521 ctcggaggag cgattgaagg acagcgtcga ctgcctgctc ctgatgcaga accccactgg
    11581 tgggttcacc gagtacgaaa ccacgcgggc atccgagaaa gtcgagtggc tcaacgcagc
    11641 cgaggtgttc ggcgggatca tgatcggata cgactatccc gagtgcacga ccgcgtccgt
    11701 caccgcgctc tccctcttca gcaaatacta tccgaattac cgggctgcag agatcaagtc
    11761 cgccaaggaa aaggccgttc agtacatcaa gcgggtgcag cgcgccgatg gcagctggta
    11821 cgggtcctgg ggcatctgct tcacgtacgc ggcgatgttt gccctggaga gtctggccag
    11881 catcggagag acgtacgaaa cgagcgcgga ctcccgacgc ggatgcgagt tcctcatctc
    11941 gaagcaaaag gaggacggcg gctggggcga gtcgtacctc agcagcgaga agcacgtcta
    12001 tgtgcagcac gagaagtcgc aggtcgtgca gacggcatgg gccagtctgg cattgatgga
    12061 ggccgggtat ccgcataagg agccgctgcg gaaagcaatg cagctgctga tgtcgcggca
    12121 gcaggccaat ggagagtggt tgcaggagtc gattgaggga gtgtttaacc aatcttggtg
    12181 agtatcatga tcgattgatt gagagttctc cactaacgag tgacagcatg atttcgtatc
    12241 ccaactataa gctgtactgg ccgatccggg ccttgggatt gtatgcgcgc aagtttggca
    12301 atgaggagtt ggtctgatct tctatggatt gttcttctat gagtacatgt attactacta
    12361 tactactata accttctact aattgataat atgattcatg tatactatct tctttatcgt
    12421 tgatctggag agtatagatg tgtagccaat cacgtggatg ctccgctccc cgcatctctc
    12481 caaagaagat catcgaactt gtttccattc cattcacctc tccacttgta ttcctctttc
    12541 tctttcacgt tatttccttt tctcttcgga gattccctta caaacaacaa gactcatttt
    12601 tcacatctcg tactcagacc catacttaaa ccctatctac ccacccaaca aacacaacac
    12661 aacacagcac aacgcaacac ctccatccaa acaccaccac actccaaccc accacctcaa
    12721 aacctcaaaa tgaacgccgc ctccctcggc gacaccgccc tccaacagtc cgacccccac
    12781 accgcaacaa ttcactacac gaccgccctc ctcacgcacc cccgctcgcc cagctacttc
    12841 atcaaacgct caacagcctt ctcacgccta aagcccacac cgaacctctc cgccgccctc
    12901 cgcgatgccg aatccgccgt tcttctcgcc cgcgagcggg ggaaacgcga gctgatcgtc
    12961 gaggcgcaga tgcggagagc catcgttttg tttctcatgg ggagatacgt tgctgcggag
    13021 ggggtggtag gcgtggtgga gggtatgatt ggattggata aggacggtaa tggtggggaa
    13081 gataaggagg agaaggtgag gaaggcgatg gggggtggtg ctgggaaggg tattgaggcg
    13141 gaggtgagga tttggggggc gaagattagg gcgaaggtca acggtttggg cgagcagagt
    13201 ggtgagcgtg gggagaaggt ggaggaggtt ccggtggggg ttaaagtgcc gggggagaag
    13261 gagttgaggg gacagttgga ggagttgagg ggagggaagg ttggtgaggg tattggtggt
    13321 gaagagaagc agagtcagaa ggttgaggat aaggtggagg agaaggagag agctgaggtc
    13381 aaggagactc agcagcagca gcaacaacag cagcagcagg tcaaggtccg tcatgaatgg
    13441 taccagtccg gtgagacggt tgttgtgacg ctctacgtga aaggcgtgcc caaggataaa
    13501 gtggctattg agctgaaaga ggactcggta tgtattcatt ccccttgacc taaacatgca
    13561 agccactaac ctatatacat agacatccat ccaattcccc ctcccctccg gcgccgaata
    13621 cgacttcact ctcgacccgc tcttcgctcc catcgacccc tccacctcta aagtctccgt
    13681 cttctccaca aagatcgaaa tctccctgcg caagaaaact cccggccaga aatggagcgc
    13741 cctggaatct accaccggac ctgtcatctc tactccccag cccacggtta cacccaccac
    13801 taccaccaca caagcccaag ccccatcata ccccacctcc tcccgccacg gcgccaaaga
    13861 ctgggacaag ctcgcctcca gcctaaccca gaaatcgaaa aaggacaaga ccaagagcag
    13921 ctcaaagccc aaggatgaac aaggagaagg agaagaagat gatggagaag catccgacgc
    13981 cgaatccatc aactccgact tcggaggcgg tgatgccgtc gatggcttct tcaagaaact
    14041 ctatgccaat gcggacccgg atacccgccg cgctatggtg aagagttatg tggagagtca
    14101 ggggacgtcg ctgagtacga attgggatga ggttgggcag gggccggtta aggttaggcc
    14161 gcctagtgag tgattttctt tcttcttttc tttctcagtt tctgagagaa aggaaagagg
    14221 ggagcaagaa agaattgttg gttgaaagat ggagaagaag ggggtatgcg aattgcaagc
    14281 gtggagttat ggtctacatc catgttgtgg gtgcatgtgg gtggtgtttt aggttctgaa
    14341 gttgcttccc ttgctagtta cttgttttgt gtagcttagc ttagctctgc tttacttgtg
    14401 taatggtaat cattgcaaga tgtcgagact ctgctattac ttaccttata aacatgatac
    14461 gtagactact acatgataca cgtgatgtag aagcaagtat agtataagat aataaataat
    14521 tatatacacg aaaagcaact ccgatccaat caaacgccaa tcacatgagc aagagtagca
    14581 tagcaacctg gccatatagc acgcaagcgt tttcagaata aatcattata aatcaagcaa
    14641 tccctaagta ccaaccccaa cacctcttta tgtcttccca gaggcatagt caagaaaaga
    14701 gaataaacaa gagagaaatg taaaccacat gcgaatattt tacctcgcct ctgcatccac
    14761 ctcaccccca ttcgcatcct ggtacaagaa aaattgaata aagatacaca tatccagcaa
    14821 taacgtgcca aagctcccaa tcagccaaga cagattgacc aggatatatc gaccatacag
    14881 cgatgccagt tcatcagatc gacaccgacc atgatgcgag cgttcacaca caggcgaata
    14941 cgccaagatg gaaaggacgt aggtcaaatt gccgatacag gcgaagagga agaagagcag
    15001 ggaaacaccg tctgttgact tgcggcgata attgaggagg atctgtggga ggcgggaacc
    15061 gaggtacagg actgcgcaga ggtagccgaa aacttggcct agtgtgtcca ttttcaggtc
    15121 atcagggctg tctttatgct tgttgttgtt attcttgtcc gatgagagtg atgacgtttg
    15181 gctgatgtac cagcccagga tgccggcggc acagacgagg atgatggccg aaccgttgaa
    15241 gaaggtggct tggagcagtg ttagggttcg agggggacgg ggttgcttgg ctggttcgac
    15301 gagtggagtc actggggaga ggtgagttcc gtcgacggtc gtatgaagaa atgaagaggc
    15361 ggagtgacgg cgatgggcga gcaagggctg gtggtgagga gtgatggtag ccgatgatgc
    15421 tgggctacga gtgtccaaag gagcctggta agaggcactg cgttgtttgg aggtaagcaa
    15481 cgcggtgcgc tctgtgggct tccgaggcac gacaggggag ggaatctcag tgtcctcgtc
    15541 gtaagtttct gctgtgatgg gagagacagg ccgcggcggc gaggatggtt cgtcgcgcag
    15601 tgtgaatccc cgatagtaga agcattgtgc taagagcacc acatcggcta aagtgtagta
    15661 caccgcgaga attatcatgg ttggcaggac gccctgcagg acggcaccga ggatgttgaa
    15721 cacatcgccg gcaagccaga cgatgaggaa aagaagcgaa aggccatcag ctgagccgcg
    15781 acgaaaattt tcaatgatct gtggggagaa gaccaccacc cagcacgcaa tcgagatgga
    15841 tctatcagtg atcagtattg aacatgtcca attctagcat actctggcat aaacataccc
    15901 acatatgcca ctcagtgcct ctagatctat attgccggtg actgcgggaa acatgtccgg
    15961 gcggtgcgaa cgagagagcg attgggcgtt ttcccaatca atgctctact ctataatcta
    16021 aacaggaaga ggctagcaaa accggtcgac agcaaacaaa gacgcgttga tggaatgaag
    16081 cagatggccg gcgatgacgt tcgcagagtc tgcgaagggt gcagatcacg tgggacgatc
    16141 cggggtagct cctctcagtc tagaccaaga atggacaccc agatcgactt gcttccactt
    16201 ttacttcttt tggctgggga cgctttgttc cttgtcggcc gcaatgctct gtatcgtaca
    16261 ttctgggcct tctggtcatc tattactatc tgatcaagta atacttggcc ccgtgtagtc
    16321 tgaccatcca tttcacactc aatgggactg tgtacatcat gtgaccgatt agtcaagccg
    16381 tgacgtcgat gatcaaccag cgcccatctg aacccagcct tctcgaagct tcaacatcca
    16441 tcaatcatgt ggcttcaatg actgctccag caattcggat tccctttacg ggccctctgc
    16501 ctccgccgat tattgtccct ccgtccgctc gcacggtcgc aggtgccatt gatgcgcttt
    16561 tagccttttt gacggcccca ccgtcgccgt acctgcgcgg cgttgatgta ggcaggcatt
    16621 cccagacagt gctcttgaca ggcgctggta tctcggtagc ttcaggcctg tccgattatc
    16681 ggggtgagaa tggcacgtac atcacaaata agacgtatcg gccgatctac taccacgagt
    16741 tcgtcgctcg ccatgagttc cgcaagcgat actgggcgcg aagcttcatt gggtggccgg
    16801 ggctcctaaa ggcaaagcca aattcgacgc actgggctat caaagacatt ggtacgaaag
    16861 gctatattag ttcagtggtg acgcaaaatg tcgactcctt ccattctgtc gcgcatccag
    16921 aactacccac actcgaactc cacggctact tgcgttctgc cgtctgcatc aattgtcgaa
    16981 ctcaagtccc gcgagacgag ttccagcaat cgctcgagcg gctgaacccc gcctgggcag
    17041 agttcctcaa gaaaatggtc gatattggcg cgctgaacgc agacaaccct gaggagcaga
    17101 gacggagggg cttgaaaatc aacccggatg gcgatgtaga tttaccggag gccccttatt
    17161 cgacctttcg gtatccagca tgtccgacgt gcttggagaa gccaccccga ttgcaggatg
    17221 ggtcccaatc ccgtgtggag gtagagcgcg atggggcttg gcttccaagt tctacggcgg
    17281 gaattctgaa gccggcggtc attatgtttg gagagaatat cgacccagct gtcaggctgg
    17341 gtgcagaaga ggccatcgat gatgcgggca ggctccttgt cctgggcagc agtctcgcca
    17401 catactcggc gtggcgccta gtggaaaggg cctataaacg agggatgccg attggcatca
    17461 tcaacatagg aggtgtccgg aacgagtcga tcctctttag caaggcggaa caagagacgg
    17521 aggctgtatg ccggcatgtc cgttgcagtc tcccgtccca ggatattcta ggccctgtgg
    17581 cagcacaact gccttcactt actcatcatt agggtccatg tatagattga aaaaaggatg
    17641 tgatgtatag atggcggtga ggtgtatgaa ccgcttacag ataagcatca tagtatatgt
    17701 acaagcgata aaagttgaat ccaagcttgc attattggag acgttactat tttcaaagta
    17761 actgtatcca tcagatggaa tactctagaa aagataatta taggcactcc agaatgattg
    17821 gcaacggcga gctaagatag gcatgtaata gacgccggga tagtggagac cagcaaagta
    17881 ggagaaggcg agttacaaag tgatggcggg ccagtcagcc gcccgtccgc tgttcgattc
    17941 cagcgcgggg ctctgcattc gccggttcag atcagcatgg acatggacgg tcgcgaccgc
    18001 tcaaaaagca ggacattgca acctccaacc gccgattatc tggatctcat ctctaacttg
    18061 gcctctccca agacttttct ctttcatcac ccacgctcca cctctcgttc tcatccaact
    18121 cctgctgcgc agagtaccac cgtcgcacca tcgaccacca tggacaagca gcagcccagc
    18181 tcgttccagc agctggaaaa ggtgtgtttt gatggcttcc ctactgtcta ccaagatatc
    18241 acccatcaaa tgagagattt gtgatgctaa ctgctgattc tagcttggag aaggcaccta
    18301 tgccaccgta cgaacccctc cctccgcacg gccgatcctc ttaaatcgca ctatgtactg
    18361 acaccctctc gcaggtcttc aagggacgca atcgccagac tggcgagctg gtcgccctga
    18421 aagagatcca tctcgattct gaagagggaa cgccatctac cgccattcga gaaatatcgt
    18481 tgatgaagga gctgaagcac gagagcatcg tgtcgctcta tgatgtgatt cacacggaga
    18541 acaaactcat gctcgtcttt gagtacatgg acaaggatct gaagaagtac atggataccc
    18601 gcgccgaccg cggccagttg gaccaagcca caatcatgtc attcatgcac cagcttctca
    18661 agggcattgc gttttgccat gagaaccgcg tcctccaccg cgatctgaag cctcaaaacc
    18721 tcctcatcaa caagaaggga caacttaaac ttggagattt cggtctagcc cgcgcctttg
    18781 gcattcccgt caatactttc tccaacgaag tcgtgacctt gtggtaccgt gccccagatg
    18841 tgcttctggg cagccgcaca tacaacacga gcatcgacat ctggtctgct ggatgtatca
    18901 tggcggaact ctacactggc cgtcctctgt tccctggcac caccaacgaa gaccagctta
    18961 tcaagatctt ccgcctgatg ggaacccctt cggaacgctc atggcccggc atctcccagc
    19021 tcccggagta caagccaaac ttccacgtat atgcgacgca ggatctcagt ctcattctcc
    19081 cccagattga ccccctaggt ctggatctct tgagccggat gctccagctc cggccagaga
    19141 tgcggatcag tgcccaggac gccctgcatc acccctggtt ccgcgatctc ccgcaattgc
    19201 aggcccaatt gcagcaacag cagcagcagc aacaacaaca aatggctggg gcgtatggtg
    19261 gcatggttcc cccacagcaa acatattgag ttcttccttt gatgcgtttc tgttttcctt
    19321 atagttcgtt ttcatcatgt acagcctatc gtttaccttg acttgcgttc atctgcttcc
    19381 tcgtggaagg cttgacgagc aacggattcg gttttagaat ggggagcgcg gcgtttgact
    19441 cctgagagga cattcgaatg attcttgctg ttttctgctt tctttgcgtt gcatatggac
    19501 ccagagaacc gatggcatct cgtagataaa cttggccatt atacttatct attgctctct
    19561 attaccttcc attatcgtag cttattacaa gcgcaggggc agcagcgacg atatcttgtc
    19621 ccgcagacaa ctaaatcaat cctgacaagc ctttatcagt gccggatata agccctaaca
    19681 ttccacgcaa ccaagttgaa cacagtagct aatctcggct cgccacgaaa agacaactta
    19741 caataaggac catccttata tttttcaaac tgatttaaac actacaaata tacagtagcc
    19801 tacacatctt actttatagg tacctaaact ctgtaatata tgtaggtact ccggtcttct
    19861 ggcgggatct atatctatca cgtgattaat agtcgcgcgc gtcttccggc gcgtcctcca
    19921 atcccatcat caatctacta ttctccataa tcctacaacc acgaacaaca acaacacaaa
    19981 ggagcttgaa acgaacttaa ggctcagcat aacaaatcac tgcaccccaa tcgaaactct
    20041 tcaaccacct caaaccctca accggcgaaa gtaaacatgt ccaccgaacc caacccatca
    20101 gcccaaagac caggcgcctc cccctcacca cctcctcccg cgccggtccc cctaacacca
    20161 ggcccgcgcg cctccaaact acaagagatt ttcgacaagg cgctcgcgcg cacgctgcgc
    20221 gcgaactcgt atgcgaattt cagcgggtgt tttccgacgc cggcgaaaca tgtcccggct
    20281 agcttggaga gcgtgtggag acagttgaat gcgaagttgg aggagagcgc gaaggccgag
    20341 ttcgaggata ttctggccga gagggatgct gttaggcagt taaatgagtt ggaccggttg
    20401 gttggggagg cgaaggttag gaaggataga ggagtcggtg gggatagtgt tgcgtatgtc
    20461 tccccttcct tattcctttt tttgctattt ggcatcatta cattgggggc ctgtggatga
    20521 tggatggcta actggaatga tttgtgcttg gtaggccgca tacgttaagt ccggaggaat
    20581 tgtacaaagc gcatctgttg ccgcatctga tggagacgca ggcggatttg gatgcgaaga
    20641 ttaattcggt gcagaatcag aatgcggagt tggctgagaa ggtccaggcg cagaggtctg
    20701 agattgaaag tttgttgtcg gggttggagg ctgtggttgc tgatttggag ggtgctgcag
    20761 ccgcgacgac gcagtttacg agtgagcatc agcttcgaca ggaagctgcg cagatggatg
    20821 gagaggttaa ggctagatct gagatctgat ctggtggctt gggattttta cgatggcggg
    20881 gacagccccc ctccctttca acgttcgaat ggatcggggt atagtatgac tacgacaaca
    20941 aaacctccat atcaccggga cccatccatc cgtcttcgac cacatcctcc gcaacgagca
    21001 tcagctcttt gggcgcagct ttccggagct gctggagttt gtccttttgg cctgccagtg
    21061 cagcagcaat ggcctccttg caggttccat ctcgttcctc gtccgcagca ccgtctctct
    21121 tcgccaaggc tgctgcacca cggtaataag tctgggcgtt gcgcagcagt gtagctgcgt
    21181 tatctcgggc catgttatag tcccacggag ccaagccaag cctccaccta cccatctcca
    21241 cgtctcctct ggccagatga atctttggca ggttttcagc attggggagt ttggacgctt
    21301 tgctcaatgc gtccaaggca gcggacaggg attgccatcg aagggacagc gctttcataa
    21361 aggcctccgg ctcatacgga gggagatctg tgagcgccgt attgaaagaa gtgagcgcat
    21421 ctgctttgct gcacaggcca tctgggtcgt tggatagatc cagatcagga ccgaaagctc
    21481 gcgaaacttc ctcggagtat gttccaactt cggtccgtcc gcttctgtac aggacttcat
    21541 tcagggagca ggcgaacttg gcacgagcca gattggcctc gtagtgcctg tttgacccct
    21601 cgacatatgc cgagattcgt ttctgcagct gctctgatga atactcttct acccaagtga
    21661 caccttcttc agggttgaac gtgagtaggt tacagaggct tgtgatggct tccagttgtg
    21721 cgacagctgt gtcgacgagt gtgtccttag tcacgggctc aacaatagca gcccattgtt
    21781 cttgctggtc tgacgacttc gactcgtccg caggtggcag ttctggcggt gtatcttgca
    21841 tctgagtttc agcagggtcc atttcgccgg acgtcatctg gttgatctgc tcctgcattt
    21901 cggtgtactt gagttcttgt acagttaggc aacgttggaa gagttctatg gcttcttgca
    21961 aaagctttac tgcctgagag agccggtcat ccgatgggcg tttggattca gtcaacgcct
    22021 cggcaatgct ggtgagtact tgggctgtgt tgaaaagcgc atctgcattg tcttgctcca
    22081 ggtcaagcgc tgctctgtga gaatcaagcg ctactcgcag gacgtccaat agtggcgcag
    22141 acagctgagc agctagtttg ggatgttgcg tgatttcata ttgaactctc gctctatcag
    22201 atgtcagtaa ctaaggttac tgacggacgc gtccataacg agtagataag gcaacgatga
    22261 atttggatga cgtgtgacgt acttgttata tgccaggtca aacgcactgg gatgttt
//
