LOCUS       KZ851973.1             43102 bp    DNA     linear   PLN 20-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   KZ851973
VERSION     KZ851973.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 07:38:58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3759
            Orig. end    :: 46861
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..43102
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[<23759:23891](+), [23995:24449](+),
                     [24512:24874](+), [24941:26101](+), [26157:26428](+),
                     [26489:>26861](+)}"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(<20001..20132,20237..20690,20754..21115,21183..22342,
                     22399..22669,22731..>23102)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..43102
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..43102
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     mRNA            complement(join(4044..4867,4941..5091,5169..5263,
                     5360..5492))
                     /locus_tag="M747DRAFT_300222"
                     /product="hypothetical protein"
     gene            complement(4044..5492)
                     /locus_tag="M747DRAFT_300222"
     CDS             complement(join(4105..4867,4941..5091,5169..5263,
                     5360..5469))
                     /codon_start=1
                     /db_xref="InterPro:IPR002136"
                     /db_xref="InterPro:IPR013000"
                     /db_xref="InterPro:IPR023574"
                     /db_xref="InterPro:IPR025755"
                     /db_xref="PFAM:PF00573"
                     /db_xref="PFAM:PF14374"
                     /locus_tag="M747DRAFT_300222"
                     /note="BUSCO:EOG0926354S; GO_component: GO:0005840 -
                     ribosome [Evidence IEA]; GO_function: GO:0003735 -
                     structural constituent of ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_300222-T1"
                     /transl_table=1
                     /translation="MASRPTVTIAGADGKPTGATYPLPAVFASPIRLDVVQQVHTGMAK
                     NKRQPYAVSEKAGEQTSAESWGTGRAVARIPRVSGGGTHRAGQAAFGNQCRSGRMFAPT
                     KVWRKWHQKVNVGQRRFATASALAASSVPSLLFARGHRVANVPEVPLVVDSKTFENSAV
                     TKTKAAVALLQAVGAGADLVKVQKSRKMRAGKGKLRNRRFRQRRGPLVVYNPEVDGKEL
                     VRAFRNIPGVETSSVFSLNLLQLAPGGHLGRFIVWSSAAFEALDKVYGTTTTASALKKD
                     YLLPQNVVANADLARLINSSEIQSVLRAPKGEARTKRTNIQKKNPLRNKQVMLRLNPYA
                     AAFSKEKLGQQKVEAAKPERASKDFLNTLYEA"
     mRNA            complement(join(5836..7504,7719..7746))
                     /locus_tag="M747DRAFT_169540"
                     /product="hypothetical protein"
     gene            complement(5836..7746)
                     /locus_tag="M747DRAFT_169540"
     CDS             complement(6168..7397)
                     /codon_start=1
                     /locus_tag="M747DRAFT_169540"
                     /note="CAZy:AA11; SECRETED:SignalP(1-20); EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_169540-T1"
                     /transl_table=1
                     /translation="MFSKSILAAAALLGISAVEAHMIMTEPIPYGKDTLNNSPLAADGS
                     DFPCKLRSNTYEVTEWNTAQIGESMPLTFEGSATHGGGSCQVSLTTDLQPTKDSEWMVI
                     KSIEGGCPANVDGNLSGGASMADPTKFNYTIPDGISPGKYTLAWTWFNRIGNREMYMNC
                     APLEVQSASSKRSDVEEKRDVEKRSSTFPPMFVANVNGCTTSEGVDIRFPQPGDDIQYN
                     GEPSNLASAGAAACTGTPTFAAAGDSSTGSYSGSGSSSGSGSGSASSSAAAVVTSAPAA
                     NTYTAPAVANTPAPSSGSSGSSSGSDSGSGSNSVSSPQPSSSSSASSSASSGALSGSCS
                     VEGEWNCINGSSFQRCANGQWTPAQNVAAGTQCTAGQSSNLAISAIKLKPRTVREGRAR
                     RHAHGGHVHA"
     mRNA            complement(7641..8326)
                     /locus_tag="M747DRAFT_169537"
                     /product="hypothetical protein"
     gene            complement(7641..8326)
                     /locus_tag="M747DRAFT_169537"
     CDS             complement(7820..8272)
                     /codon_start=1
                     /locus_tag="M747DRAFT_169537"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_169537-T1"
                     /transl_table=1
                     /translation="MESLLVRDHSGSIYPPPKLCVPRLDMQPNSLSVNLLPLPTHTHLD
                     FRCAPTNSLSRSVQSPGYLIHRHGASNSPNLKYITPPRAASAAPFSSFSSSTTLERSVL
                     SSFYTVRQSYYHQASPAFFRHSFLISFESSLCACGRLRPSLLLPTN"
     mRNA            complement(join(<8352..8497,8563..8745,8840..9070,
                     9154..9240,9322..>9619))
                     /locus_tag="M747DRAFT_363579"
                     /product="hypothetical protein"
     gene            complement(<8352..>9619)
                     /locus_tag="M747DRAFT_363579"
     CDS             complement(join(<8352..8497,8563..8745,8840..9070,
                     9154..9240,9322..>9619))
                     /codon_start=1
                     /locus_tag="M747DRAFT_363579"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_363579-T1"
                     /transl_table=1
                     /translation="MAHTVGGYCTKKLLTRSASTLSLIHDPSNEESSKWYQRVAIRSRS
                     QPPSDMMKGSQRKKTVGGKRTPPIQPNFCADRVRPCGDHDLNHGAGGWMFTLCPGPEKK
                     KGYGLCGVVCFALYGAAGCNKIFTGELGIGLKDHLGDGDVFLVWFFCGRMRYLMDGLAH
                     AISYNRVLLSLTMKASRSMGTGMMTGEQTSSQYFVCVECWNHVAARLCPSPHVGFIFRK
                     GCNVRAGDLRPVGGSHLIKPNGELWRLIRRAERMIGRCGKGEMTVGSRSIRANPRPAGV
                     DWQMPAPTALGPANETAGRADGATDGLAGGNIY"
     mRNA            complement(join(<11177..11208,11290..11335,11397..11476,
                     11545..11761,11820..11915,11987..12115,12217..12599,
                     12656..>12707))
                     /locus_tag="M747DRAFT_249972"
                     /product="aromatic compound dioxygenase"
     gene            complement(<11177..>12707)
                     /locus_tag="M747DRAFT_249972"
     CDS             complement(join(<11177..11208,11290..11335,11397..11476,
                     11545..11761,11820..11915,11987..12115,12217..12599,
                     12656..>12707))
                     /codon_start=1
                     /db_xref="InterPro:IPR015889"
                     /locus_tag="M747DRAFT_249972"
                     /note="SECRETED:SignalP(1-18); EggNog:ENOG41; GO_function:
                     GO:0016702 - oxidoreductase activity, acting on single
                     donors with incorporation of molecular oxygen,
                     incorporation of two atoms of oxygen [Evidence IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_process: GO:0055114 - oxidation-reduction process
                     [Evidence IEA]"
                     /product="aromatic compound dioxygenase"
                     /protein_id="ncbi_M747DRAFT_249972-T1"
                     /transl_table=1
                     /translation="MKSLLLGSAFLLASFIHAHPGPHAQPDPVHLARRGALAKRCSDTV
                     GLMKRKRHAMRRRALSPSEDDGSGTTTYTITADAPKYDFLKNDTCILTPETSTGPYIYP
                     RSQVLRQDIVEDQVGVPFVLDIGLMDIHTCEPLSNALVDIWQCNASGSYSSFTGLDPDI
                     PFQDQYFESTGEQLPAKNEGESDTSFLATDNTTWLRGMWPTDDNGATSFTSIFPGFYTN
                     RAIHVHLQVHTDWTITSNGTIGGSRTVNTAQLFFNEDVATQVMAVPPYAYHTQIPRKPV
                     SQDGVWYEESLTGAMTIMDTEPLDGQDYANRVLGYITLGVDTTAIHNGTTENPNPSIPT
                     SASA"
     mRNA            complement(join(<13131..14069,14133..>14204))
                     /locus_tag="M747DRAFT_250003"
                     /product="NAD(P)-binding protein"
     gene            complement(<13131..>14204)
                     /locus_tag="M747DRAFT_250003"
     CDS             complement(join(<13131..14069,14133..>14204))
                     /codon_start=1
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF03435"
                     /db_xref="PFAM:PF05368"
                     /db_xref="PFAM:PF13460"
                     /locus_tag="M747DRAFT_250003"
                     /note="EggNog:ENOG41"
                     /product="NAD(P)-binding protein"
                     /protein_id="ncbi_M747DRAFT_250003-T1"
                     /transl_table=1
                     /translation="MAVKYAKDQPPGFSNRMERVAIVGAGGSIGHYIATELVRTGKHTV
                     TGLTRSGSKNKLPEGVKPFYIDYDDESTLVKALQDQQFLIITMFVIAPPDTQAKLIRAA
                     AKAGLPYVMPNAYGSDFTNDALAKETRRGDVIRKSLQEIEATNVCSWIALVCGFWYEFS
                     MARGAECFGFDVQRKHLTLIDNGNTKINISTWDQCGRAVAALLNLKELPDGPGDTSPTV
                     NTWKHRPLYIASFTISQRDIFESWKRVTGDKDEEWTLEYAPSHERYAQGQERLKKGDKL
                     GYVQMLYTRQFYPNGDGNFGEKHGLANDALGLPRENLDECTKRVKEMIEGGFAYH"
     CDS             join(<14760..14968,15037..15208,15268..16071)
                     /codon_start=1
                     /db_xref="InterPro:IPR002227"
                     /db_xref="InterPro:IPR008922"
                     /db_xref="PFAM:PF00264"
                     /locus_tag="M747DRAFT_363580"
                     /note="SECRETED:SignalP(1-19); GO_function: GO:0016491 -
                     oxidoreductase activity [Evidence IEA]"
                     /product="Di-copper centre-containing protein"
                     /protein_id="ncbi_M747DRAFT_363580-T1"
                     /transl_table=1
                     /translation="MQLKWLTLVCLSSWPSARALYNQSTGFPEQDLDNGVALQQIADNA
                     LNNMEQESLTANGCRLEDAQIRREWRSLSPNARKEFTDAITCMQSRPTNISAEEKETFQ
                     GVKTRYDEFVATHINLTEHIHVTADFLAWHRFFIHAFENALRVECNYTGTLPYWEWGLD
                     AENPQDSVLFNGDLYSMGTNGVDLNRTSIYWASQNITIPAGTGGGCVYGGPFSNYTVHM
                     GPIDAPGEQPVQYNLEYNPRCLSRDVNPSVSRMSNSFRNTTKLILSYDTIDWFQGVMQA
                     DQRFTDPTAPFSYGVHGGGHLTVGSVLADIDTSPAEPMFWLHHAQIDRVWTIWQGLDPA
                     KRRNAIWGTSTRGDDPPSANMTLDDSLNFGFISQPLRFADLMNPLSGPFCYYYA"
     mRNA            join(<14760..14968,15037..15208,15268..16247)
                     /locus_tag="M747DRAFT_363580"
                     /product="Di-copper centre-containing protein"
     gene            <14760..16247
                     /locus_tag="M747DRAFT_363580"
     CDS             join(<17205..17261,17318..18647,18731..18888)
                     /codon_start=1
                     /db_xref="InterPro:IPR002018"
                     /db_xref="InterPro:IPR019826"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="PFAM:PF00135"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_270554"
                     /note="MEROPS:MER0033188; EggNog:ENOG41"
                     /product="carboxylesterase"
                     /protein_id="ncbi_M747DRAFT_270554-T1"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.1e-07, bitscore:
                     22.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MPIHRHPLLLCKSAMAHTRPPVGELRFRPPQPLNTTWTGTRNATA
                     YYNECIGYGSDDWYWTDVVSEDCLALSVIRPHGIDSSAKLPVVFWMHGGEFAEGGTRDS
                     RYNLSYIVQQSQEMQSPIIGVTVNYRLSGWGFLYSQEVADEGSANLGLRDQRHALYWLQ
                     ENIASFGGDPSRLTIWGQSAGANSVGLHLVAYDGQNDGIFRAGIAESGSVPSLAAYMSA
                     EDAQPYYDAVVNATNCTGSSNTLTCLREVPTDVLSSIFNSSLVAGAGYHPVIDGDFLRA
                     SGIVNLQTGQFAKTPLLIGTNFDEGTKYAPHGYNTTDQFVSLVQANGTNYTSALTIASL
                     YPDDPAVGIPGTLQGRPPPSYGYQWKRVAAFLGDLLMHAPRRVTTQWLAHWNVPAYVYH
                     WNVMTLGPLDGAAHGYEVPFSFHNYDGLGDERGNDSVTWPQLSTMMSRMWVSFINHLDP
                     NYSNMTDIHWPVYTTETPQNMVFDVNVTGLAYVEPDTYRAEGIAYITSILQSAFNR"
     mRNA            join(<17205..17261,17318..18647,18731..18901)
                     /locus_tag="M747DRAFT_270554"
                     /product="carboxylesterase"
     gene            <17205..18901
                     /locus_tag="M747DRAFT_270554"
     mRNA            join(<20001..20132,20237..20690,20754..21115,21183..22342,
                     22399..22669,22731..>23102)
                     /locus_tag="M747DRAFT_311054"
                     /product="acetyl-CoA synthetase-like protein"
     gene            <20001..>23102
                     /locus_tag="M747DRAFT_311054"
     CDS             join(<20001..20132,20237..20690,20754..21115,21183..22342,
                     22399..22669,22731..>23102)
                     /NRPS_PKS="Domain: AMP-binding (49-422). E-value: 2.4e-53.
                     Score: 172.8. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_311054_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (559-631). E-value: 7.1e-11. Score:
                     33.9. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_311054_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (653-901). E-value:
                     1.5e-30. Score: 99.0. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_311054_Thioesterase.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /codon_start=1
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001031"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="InterPro:IPR036736"
                     /db_xref="InterPro:IPR042099"
                     /db_xref="PFAM:PF00501"
                     /db_xref="PFAM:PF00550"
                     /db_xref="PFAM:PF00975"
                     /db_xref="PFAM:PF12697"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     211.9; E-value: 2.2e-64)"
                     /gene_kind="biosynthetic"
                     /locus_tag="M747DRAFT_311054"
                     /note="EggNog:ENOG41; GO_function: GO:0003824 - catalytic
                     activity [Evidence IEA]; GO_function: GO:0016788 -
                     hydrolase activity, acting on ester bonds [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /product="acetyl-CoA synthetase-like protein"
                     /protein_id="ncbi_M747DRAFT_311054-T1"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-65, bitscore:
                     212.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.1e-11, bitscore:
                     32.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.2e-11, bitscore:
                     34.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MAPGILTYLEQAAEYSPSKGFVFYSVGKDQPETILYPDFWRLVKK
                     VAVPDRVLLVHFDTHKENIIWFWSVIAAGCVPAVSTPLAVDPVARERHLTHLQRLLERP
                     NVLTSVKHTDDLSIIDDSQKFFIEDLASNADQSADYQPASPSSDLALLLLTSGSTGNAK
                     AVMLHHSQILAAIEAKWKALSSTPDNVFLNWIGFDHVACFMEMHMHALSRGCHQIHLPA
                     VTVLENPILYLEKMAEYSVTNAFAPNFLVALVGKAIEAQQERDPRALDLDLSHLRIVLS
                     GGEANLTSTSIIFNRKLVEMGAAKNVLHPSFGMTETCAGIHYHYSFPELEQKAKLQFCS
                     VGQTTPTLQMRITDENGETVRSGENGNLELYGPMVFKGYYNDDKNTKAAFTEDGWFKTG
                     DTGYIDNRDNLVLSGRSKDSIIINGINFYSHELENAIDSAGLEGLVPSYTVVVSSWLEN
                     ADSEDVIVLYLSSQKGTEDDRIFLETLNSISRITALYCSKQPVDIIPLPVELLPKNSLG
                     KLPRTKLKQQYEEGRFSTYRDLAAQRASSYRARSKRAPQNDMEETLAGIFADEFGLDMS
                     EVGVDDSLYDMGVNSVRLIRYKRIVETRLGLTEEIPMITILQNPTIEALAVMLQDLQKG
                     PKPYDPIVQLQDGPSKAPPIFFFHPGMGEVLVFLNFSKYFADRKVYAFRAPGFNPGEKM
                     FTTIDEMTDVYLKSIRELQPEGPYIFIGYSYGAMIAFETAKKVEASGDRVGFLGSLNLP
                     PHIKKHIREMDYAESLLHLVYFLGFITEEDAHRMSPDMHKLPQSEVLPAIMKVSDKERV
                     QELAMDEGKIRDWAMLSSKLQELAHTYDPSGTVQVMDVFYAIPLLSVGRDKDVWLKQHL
                     MRWKEHSKSVRFHDVPGSHHTMMAEENVFALHKILRAALNERGML"
     aSDomain        join(20252..20690,20754..21115,21183..21500)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_311054_AMP-binding.1"
                     /evalue="2.40E-53"
                     /label="M747DRAFT_311054_AMP-binding.1"
                     /locus_tag="M747DRAFT_311054"
                     /score="172.8"
                     /specificity="consensus: hydrophilic"
                     /tool="antismash"
                     /translation="DRVLLVHFDTHKENIIWFWSVIAAGCVPAVSTPLAVDPVARERHL
                     THLQRLLERPNVLTSVKHTDDLSIIDDSQKFFIEDLASNADQSADYQPASPSSDLALLL
                     LTSGSTGNAKAVMLHHSQILAAIEAKWKALSSTPDNVFLNWIGFDHVACFMEMHMHALS
                     RGCHQIHLPAVTVLENPILYLEKMAEYSVTNAFAPNFLVALVGKAIEAQQERDPRALDL
                     DLSHLRIVLSGGEANLTSTSIIFNRKLVEMGAAKNVLHPSFGMTETCAGIHYHYSFPEL
                     EQKAKLQFCSVGQTTPTLQMRITDENGETVRSGENGNLELYGPMVFKGYYNDDKNTKAA
                     FTEDGWFKTGDTGYIDNRDNLVLSGRSKDSIIIN"
     CDS_motif       20552..20611
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_311054_0001"
                     /evalue="2.20E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="M747DRAFT_311054"
                     /score="17.2"
                     /tool="antismash"
                     /translation="ALLLLTSGSTGNAKAVMLHHS"
     aSDomain        21912..22127
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_311054_PCP.1"
                     /evalue="7.10E-11"
                     /label="M747DRAFT_311054_PCP.1"
                     /locus_tag="M747DRAFT_311054"
                     /score="33.9"
                     /tool="antismash"
                     /translation="EETLAGIFADEFGLDMSEVGVDDSLYDMGVNSVRLIRYKRIVETR
                     LGLTEEIPMITILQNPTIEALAVMLQDL"
     aSDomain        join(22194..22342,22399..22669,22731..23054)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_311054_Thioesterase.1"
                     /evalue="1.50E-30"
                     /label="M747DRAFT_311054_Thioesterase.1"
                     /locus_tag="M747DRAFT_311054"
                     /score="99.0"
                     /tool="antismash"
                     /translation="PIFFFHPGMGEVLVFLNFSKYFADRKVYAFRAPGFNPGEKMFTTI
                     DEMTDVYLKSIRELQPEGPYIFIGYSYGAMIAFETAKKVEASGDRVGFLGSLNLPPHIK
                     KHIREMDYAESLLHLVYFLGFITEEDAHRMSPDMHKLPQSEVLPAIMKVSDKERVQELA
                     MDEGKIRDWAMLSSKLQELAHTYDPSGTVQVMDVFYAIPLLSVGRDKDVWLKQHLMRWK
                     EHSKSVRFHDVPGSHHTMMAEENVFAL"
     CDS_motif       22427..22495
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_M747DRAFT_311054_0002"
                     /evalue="3.80E-10"
                     /label="NRPS-te1"
                     /locus_tag="M747DRAFT_311054"
                     /score="32.1"
                     /tool="antismash"
                     /translation="QPEGPYIFIGYSYGAMIAFETAKK"
     mRNA            complement(23877..25171)
                     /locus_tag="M747DRAFT_169576"
                     /product="UPF0029-domain-containing protein"
     gene            complement(23877..25171)
                     /locus_tag="M747DRAFT_169576"
     CDS             complement(24032..25159)
                     /codon_start=1
                     /db_xref="InterPro:IPR001498"
                     /db_xref="InterPro:IPR006575"
                     /db_xref="InterPro:IPR016135"
                     /db_xref="InterPro:IPR020568"
                     /db_xref="InterPro:IPR020569"
                     /db_xref="InterPro:IPR036956"
                     /db_xref="PFAM:PF01205"
                     /db_xref="PFAM:PF05773"
                     /locus_tag="M747DRAFT_169576"
                     /note="EggNog:ENOG41; GO_function: GO:0005515 - protein
                     binding [Evidence IEA]"
                     /product="UPF0029-domain-containing protein"
                     /protein_id="ncbi_M747DRAFT_169576-T1"
                     /transl_table=1
                     /translation="MRDNILKPRGIKSTIVPAATQGCPALPYPAKMDSALESLQNTDLA
                     EEIEAINAIYEPDTLTITNTSTSTGPSTLDLGGSGSSDSSPPSTTIKLQLPEHPHLSFL
                     LGFNSTYPDTPPKILGTASTASRGEGKLAVDVLEDILSRTYQPGAVCLFDLINEAVQAF
                     TELNIGGSATTTTTNNNDTTSHTQPASEELNTENGSHQPLTTRSTTPDHHTFNLTSPPP
                     WILSDVITEKKSVFVGRAAHVTSLDQAKAFLDHLLATEKKVASATHNISAWRIREVKSS
                     TSTAGGSKNGEATEMIVQDCDDDGETAAGGRLLHLMQLMDVWDVVVVVTRWYGGVLLGP
                     DRFRIINAAGRDALVKGGFVKEKTAGEKGKKKGKK"
     tRNA            25257..25328
                     /locus_tag="M747DRAFT_t273"
                     /product="tRNA-Arg"
     gene            25257..25328
                     /locus_tag="M747DRAFT_t273"
     mRNA            complement(join(25457..26688,26756..27338,27437..27747))
                     /locus_tag="M747DRAFT_169592"
                     /product="aromatic amino acid aminotransferase"
     gene            complement(25457..27747)
                     /locus_tag="M747DRAFT_169592"
     CDS             complement(join(25614..26688,26756..27338,27437..27572))
                     /NRPS_PKS="Domain: Aminotran_1_2 (106-389). E-value:
                     5.9e-11. Score: 33.7. Matches aSDomain:
                     nrpspksdomains_M747DRAFT_169592_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="InterPro:IPR004839"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="PFAM:PF00155"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 150.2; E-value:
                     1.4e-45)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="M747DRAFT_169592"
                     /note="EggNog:ENOG41; GO_function: GO:0030170 - pyridoxal
                     phosphate binding [Evidence IEA]; GO_function: GO:0003824 -
                     catalytic activity [Evidence IEA]; GO_process: GO:0009058 -
                     biosynthetic process [Evidence IEA]"
                     /product="aromatic amino acid aminotransferase"
                     /protein_id="ncbi_M747DRAFT_169592-T1"
                     /transl_table=1
                     /translation="MVYSTLSPPLDLSHHFSSVTKRREASETKSLYKYFFIPGIANLAG
                     GLPNASYFPYDTLEATVAHPQRFPATSDNDQIKPPSGSPSTERRIVPKESPTTNLLKKI
                     DLTTALQYGTAEGLPVMADFVRQFTRNHLHPNVPYAGGPGTLLTCGATDGFSKAIETFT
                     NPWDPRRDWISQREGILCEEFVYMNAIQTVKPRGLNIVPVAIDAQGMLAHGKGGLADVL
                     ENWDFKKGRLPHLMYTITIGQNPTGGTLSVERRREIYALCRQFDIIIIEDDPYWNLQYP
                     SATAMEAGFRGSDAVDVIPRNYNAHGRSSGYDFLDSLVPSYLSVDTDGRVVRLDTFSKT
                     IAPGCRLGWITAQPAIIERLTRLTETSTQQPSGFVQAMVAELIVGQQSEDGQNATGASK
                     NKSKKSEQAWQMDGWVRWLEGLRAGYEQRMTTMCTILEEGKYLIDSGSAWDDAQPMAED
                     ETAWEVLDKMQMYEFSWPTGGMFVWVKVCIETHPLLEKYGPEKLIQALWLHLMQKPYLC
                     LSGPGTMFAPTTELLDRAQTYYRLCFAAMPAEDVLGITRRLVDGFRAFWQRKNLDGLDD
                     EEIALSRLQAKGSGNLLGLGC"
     aSDomain        complement(join(26241..26688,26756..27156))
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_M747DRAFT_169592_Aminotran_1_2.1
                     "
                     /evalue="5.90E-11"
                     /label="M747DRAFT_169592_Aminotran_1_2.1"
                     /locus_tag="M747DRAFT_169592"
                     /score="33.7"
                     /tool="antismash"
                     /translation="TTALQYGTAEGLPVMADFVRQFTRNHLHPNVPYAGGPGTLLTCGA
                     TDGFSKAIETFTNPWDPRRDWISQREGILCEEFVYMNAIQTVKPRGLNIVPVAIDAQGM
                     LAHGKGGLADVLENWDFKKGRLPHLMYTITIGQNPTGGTLSVERRREIYALCRQFDIII
                     IEDDPYWNLQYPSATAMEAGFRGSDAVDVIPRNYNAHGRSSGYDFLDSLVPSYLSVDTD
                     GRVVRLDTFSKTIAPGCRLGWITAQPAIIERLTRLTETSTQQPSGFVQAMVAELIVGQQ
                     SED"
     mRNA            complement(28759..30797)
                     /locus_tag="M747DRAFT_169608"
                     /product="MFS general substrate transporter"
     gene            complement(28759..30797)
                     /locus_tag="M747DRAFT_169608"
     CDS             complement(28907..30664)
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1169:sugar
                     transport protein (Score: 60.9; E-value: 1.8e-18)"
                     /gene_kind="transport"
                     /locus_tag="M747DRAFT_169608"
                     /note="EggNog:ENOG41; GO_component: GO:0005887 - integral
                     component of plasma membrane [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="MFS general substrate transporter"
                     /protein_id="ncbi_M747DRAFT_169608-T1"
                     /transl_table=1
                     /translation="MLWTDLSIPLAFNMQSFLQYRRLRRHLHESIKIHGPAAAGDPNSQ
                     PSGDILEDYEDARLDRQHLANRPSAAVPSSSRNSISSQGMPGVVLQNGRRVTVPGVSVH
                     SATDVEFTNGEAIFIVGFDGPGDPFNPKNWPVRQKWTTLGIVGTTGFLVGWASSIDSGV
                     IKQGEEAFGVSEVTESLATALYLVAFGFGSLVAAPFSETVGRNPVYLVTLSLLMIFIMA
                     SGLSPNLGAQLAFRFIAGLFGCTPLTTFGGSMSDIFDLLDRTYAFPVCCALSFLGPFLA
                     PMVGAFIGQSSVISWRWSEWTSLILAGLITASIFFFVPETYGPVLLQWKARQLRTITGD
                     PRFMAEIELRQTTLPIRLMHSCSRPFKLFFQEIMVALFTMYLVVVYIVLFGFLTGYEFI
                     YGRTYGFSQGSVGLTYIGMNVGFLIALAIVPHVYLSYKRRLQTAIASGKPSLPPEERLW
                     FAMYGAPWLPISLFWMGWTSYPSVSYWSPLIASVAFGFSVQGIFISSYQYLIDTYEIFA
                     ASALVSATFMRYIAAGAMVIVSIPMYTNLGVHWSLTLLGCISLLMTPVPYIFYRFGHAI
                     RRRSKSAAA"
     mRNA            complement(30798..32669)
                     /locus_tag="M747DRAFT_169607"
                     /product="hypothetical protein"
     gene            complement(30798..32669)
                     /locus_tag="M747DRAFT_169607"
     CDS             complement(30931..32616)
                     /codon_start=1
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR007219"
                     /db_xref="InterPro:IPR036864"
                     /db_xref="PFAM:PF00172"
                     /locus_tag="M747DRAFT_169607"
                     /note="EggNog:ENOG41; GO_component: GO:0005634 - nucleus
                     [Evidence IEA]; GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_function: GO:0008270 - zinc ion binding
                     [Evidence IEA]; GO_function: GO:0000981 - DNA-binding
                     transcription factor activity, RNA polymerase II-specific
                     [Evidence IEA]; GO_process: GO:0006351 - transcription,
                     DNA-templated [Evidence IEA]; GO_process: GO:0006355 -
                     regulation of transcription, DNA-templated [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_169607-T1"
                     /transl_table=1
                     /translation="MSSALDRSSRPPIGSIRRRTKKACETCKLRKRKCDGHEPCSFCLK
                     YEYDCAYEAQPRKKPSRPSIARPSTKPLERASSPALAARADVNQQQMEANSGTAFPHFL
                     GKSLNPQNPPKVHGFSWNLGLRHEPIQQFANISSLVSKDEMSALVGHYLERIHPIYAVL
                     DLDMLEKKVGLRWDNSITFDSYDPVLCGVAALGSLYSGDNGHRNEEALVQCAKEILEAT
                     CTMNKPLIHHATGWVLRTLYLRSTGCPHTSWMASCSAMHIIEAAGAHQDPGMISLVYSD
                     TADVGVDEESQRRLFWVATVLNTWISYEYGRSRVILRGISCKPPVPRAGDLTAELVSLF
                     QISQRLDPDQNNRPSDLEDVLYHVQSLTLSHDALVLSQANLALTIYRRLRVAASSISND
                     VINCVIRMGSDGTAAAVRMSENRSPWWHVANVPFQFLCILLAIDSKESLSHVGHAMRSF
                     KTIGSHFNTPTVHIAIETVDSLIKLLQRKKEREINLLRDSIQDQDSGPFERNLSSTQEY
                     GSPLQGGLFDGNNLEMIDWDWNAFFDAEIPLFDDRGHGGQMRYG"
     mRNA            join(34590..34744,34831..34896,34976..35075)
                     /locus_tag="M747DRAFT_375172"
                     /product="hypothetical protein"
     gene            34590..35075
                     /locus_tag="M747DRAFT_375172"
     CDS             join(34664..34744,34831..34896,34976..35011)
                     /codon_start=1
                     /db_xref="InterPro:IPR009101"
                     /db_xref="InterPro:IPR024206"
                     /db_xref="PFAM:PF11410"
                     /locus_tag="M747DRAFT_375172"
                     /note="SECRETED:SignalP(1-17); EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_375172-T1"
                     /transl_table=1
                     /translation="MKFSIFATLAFLGIALASPAANTATSTLPSGATCNKDGSMGNCAS
                     GLCIQEENASTGTCQ"
     mRNA            complement(join(<35400..36408,36500..>36744))
                     /locus_tag="M747DRAFT_363608"
                     /product="hypothetical protein"
     gene            complement(<35400..>36744)
                     /locus_tag="M747DRAFT_363608"
     CDS             complement(join(<35400..36408,36500..>36744))
                     /codon_start=1
                     /locus_tag="M747DRAFT_363608"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_363608-T1"
                     /transl_table=1
                     /translation="MPLRITPSHKAVYEPSSDAAPDFSDLSELSEDDHLDSEDDALLDH
                     NGYEIGPAIATTQLSIHHYNVKEWDTRDAYRELYKFWKQTIVKSFAVEDTFHHEHEETR
                     NWITVKALIPTWPGYMGFIRYSKTTGTITFINADALLLQSTDNNHTPETENFTNDTTFF
                     FRFQNERLKAVAYVLLRSGFNIQITSQKYIWTFNIPSIADSSPKIPNLLSCTVNTLNGT
                     HKPTTPTTTPYQPRPAHDLTITITSSHPQIPLLLPPHTFRTWLRVSLHLTPKPPSANII
                     PTPHGDILLDPEFSGTLYLRGILLPELSFDRCRYKYGYNLHYGIPTTSGRRLASPLHEV
                     DLICSVWGAAICSAPVYVLPRFVDMVFGGVPWPVEVMWADGGGMAAEAVEAVWWSLLVR
                     GGEGVFYYCGARGEEEVC"
     mRNA            complement(join(37155..38762,38817..39276))
                     /locus_tag="M747DRAFT_169619"
                     /product="hypothetical protein"
     gene            complement(37155..39276)
                     /locus_tag="M747DRAFT_169619"
     CDS             complement(join(37475..38762,38817..39058))
                     /codon_start=1
                     /db_xref="InterPro:IPR018535"
                     /db_xref="PFAM:PF09362"
                     /locus_tag="M747DRAFT_169619"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_M747DRAFT_169619-T1"
                     /transl_table=1
                     /translation="MSMWFTDQEVRLAPACLHDHASAKPGFIGFSMSSGETALKNADCT
                     SCGVTQDKSAYWAPALYFMHENGDAELVNEVGGMLAYYFLNGQNVTAFPENFRMIAGDP
                     FLRNFPWPVPDPPKSEWSGNQSSQDALRQKALGFNCLNYNKSPEPSLGRHFLPNKTFLD
                     EHCTDGVRFELMFPSCWNGKDVDSEDHRSHMAYPSLVMDGVCPEGFETRLVSLFYETIW
                     DTYAFKNKQGTFVLANGDPTGYGYHGDFIYGWQYGFLQQAVDECTNLSGRVEDCPIFDL
                     QTDTEQAQCNFTMPEELKSENVYLHKGGLPNNIAIQYGPAYASPVRYTNAGHHTSAILP
                     EPSIAIGASLNGATVDLGNIHIGVTLGAGAPSTTTTTSSTLSTSTLPSSTQTSTLTTSA
                     ASAYFFQTSTSTTPTSTWTPTPTTSYVEGVVTQKIVYVEQEILILTDENGAPVTTETGG
                     IETVSTSTSTVNKIVSTVVTTPTEAPAKRDGHSHGHFQHVHRRHRHGHAHR"
ORIGIN
        1 ccggccgtga tggtcggagt ccatatccgg aacctccctg ggtcttctcc gataggatca
       61 actagcgccg gagggggtga gacacagtgc tttttgtgtc gtcgcatatt ggtgtctcaa
      121 gggcgaataa atatcgcatc aattacaatc accattgttt ccgctcatcg gtcatccttt
      181 ctggccaact atgcaaagcc agactgcatt attcaattca ttatcaacta ataagaacat
      241 caagccagac agatactagt ctaactactt agaaactact tactccaact tcgcaggcgc
      301 catctccggc cgaaaacata tccactccac ccgacaaaac ccgtccgtcg atcccacttc
      361 cctccccctc cccattcatc catcatcacc acccaatatg caaaacaccc cggcagcgac
      421 gcgaccgcta atccagtagt gggcgagcag tgcgaaacgc accataggta cgtacccccg
      481 acatatgctg atgatattgc caccccgact atcacatcag aggctgcagg cgacggtttt
      541 agcccaaaag cttgttgtag ccgcggcgcc aaagtgggat gaggtggggg tcgtcgagga
      601 tcaatagtcc atggtagcgt gtctggcgtc ctgaatcatg aaggctcgct tgctcaatca
      661 cttcggaagt taaaccgaat cggtcgataa ggtgtgagtt tcaagttgtg ctgtctggtt
      721 aatcccacga actacgggcc cttggaagtt ggccaagggt aaaaattgag aaggggaggg
      781 ggggggtaag aaaaaagggt cgaccacctc ggctatcaga ggaagcatgg accgagatat
      841 gctacgatac tatccacgcc atcatcatcc ctgagagatc atgacacaaa gtacgaagta
      901 cacggtgtac taaggtgctc ggccgtaagt gctaaagtag gtttcctccg ggaatactac
      961 tcatttgaac aatatctgtt aataaactaa tgaggagaaa gttaggcacg tcgtgcttga
     1021 actactactc aaccgagtat gttgaagcga ttttcaatcc cttgggtctg tctgtctgtg
     1081 agaacttaga gaggcaattt aagcgcaccg gaggattgat atcgcccgat actacgttat
     1141 aatataagac aatataataa gagccataat aagaaacata agcctacact aatatccgga
     1201 agtcccgcaa taccgtatac caagtatata caacgacccc cattgtcatg tgagagtctt
     1261 ttcaagcttc aaaccaatat gaatatgaaa acaatatgat ataacttccc cctcgtatcc
     1321 cctgagtgtc ccccctctac gagaacgaga gagaagaaga agaagaaaga gtaagagaaa
     1381 caaagtgtag accgagccga ccactaattc cccccatcaa catacgtaac agaggggctt
     1441 ggcgccgccc cccgtcaaaa aaatgagtcc gaaaatcgcg gaaaagccga gcgggatcaa
     1501 tcaagcttgt gaaacacaca cactcacact cacacccttg acacatacct ccctcactcg
     1561 caactcacac cataagtaga tagaaacgta gtgcaaagtg gagagcaggg ccgccgcccc
     1621 gaggaagttg actttcctat ttgccgtgat cagagcaaat gccgatgagc tggcttttct
     1681 cttatttttt ccttttcttt tcttttcttt gttttgtgtt tgatgatcct tatcggtttt
     1741 ggttcctcat ccgtagttag tatttaccaa ctatgtcata attgatgact tttttttttt
     1801 tttgcctgat cggcttttct tccctacatt ccgtttccat cggaattttt ttcttcttat
     1861 ttcttttcct gtattctatt gttttcaatt tctataatat tgcgttgtca gttcgatctg
     1921 cagtttcagg tagtttgcta catacctacc gtagtgccta aatctaaatg agtagtatgt
     1981 accgaccgag ggtggataga cgatagaacc cgttatggtg ttcatattta tattcataac
     2041 tagtacttat gttctcccta cctgacacat agggcatact agtagttaat caagataatg
     2101 gtggcaagta gttattagta ggactaagtc ctaggtagac aacgccctac aactaagaca
     2161 cctaattcag attacagata gctaataata tagaatcaat tatactatct atccgacatg
     2221 gcaataataa gatataatat actactacta ctactactct gtaatatagt aagcgatgat
     2281 actacagtga actcaaccac ctcggatcta accggctcat ctacccattc atccaccaac
     2341 acttaggacg ccaccaactt aacccccgac ctccgaccag aaagaaagta agaacagagc
     2401 accaccgacg gaccaacgga gtgggaaagg aggggattcc accccctgta gaacaaaaga
     2461 acgagactaa cccttctgcg caaatgcaca tgaggaagat gattcgttgg gagggcagat
     2521 gttgcagtag tagttgacta gtagtttaag tagggaggat ctaaggccta aggtactccg
     2581 tgctaagtgc tttagtaagt agttcgggta agtagttttg gccaggattg gattgcatat
     2641 gattgggttg ttggttgcga tgtaaagtaa taaggaaaaa taaaaaaaaa agaagtgaga
     2701 tggtaattta ttatgttgat ggtcagttgg atgaactatt accctagtga atgtgatact
     2761 tcttcttcta gatgatattg tattttatgt agttgttgtt gagacggtgg ttacttagta
     2821 ttgtatttgt gcgttgtagc agtgatgcgc gtgggtttag aactaacgcg catcataata
     2881 atctctttgt atctaactac catctacacc agatcctgct actcagtaat aggggtgtaa
     2941 caactaagta gaactgtgag gaaactccga acgggtggca tgatgcttgc tcaagagtcc
     3001 actgcggttt cacaataata tatataaact ttgcactgtc ttcaatttga ctttctacta
     3061 gtatagctta gtgattgatg gaattactac ttactactgc agcaaacata gccaccttag
     3121 gcagaaacta ctactgcgca tgaaaggtcc gtgtccgttc gtctagtacg ttgtagttgc
     3181 agtcactggt tactagtaat gtgggtattt atatatcccg atgcaagtcc cgaaccgaca
     3241 gctactattg actacgtact tacgtacttc gtagtaactt gaagtaaaaa tggttaccaa
     3301 tcccttacga tcgaattgta gtaggaaagt agttaattaa ctagtagcta gcttattact
     3361 atcttgtcgt gactagttct tgaaggtaat attatggtaa ttgctcagtt gtggttcagt
     3421 ttcctatact ggtgacacat tgtcatgtga aaatactcac atcctaatac gacttcctac
     3481 tatccatttt atccctgtaa tcagcagaat agcaaacaaa aatcaatgct cgggtcaacc
     3541 cggcgataac agccaaaatc aagtagcgcg aacatagttt gttcacatgt ttgcttgttt
     3601 gtgtcctgag ttaggttgat gatcctgggt tatagcaggc gtagatatag atggtagcct
     3661 gggttggtca gatgtgataa taagccagat attggggttt gactgattga caaagtatgc
     3721 tttctaggtg ccgtgtagaa gatcatgcac cgttgattat tttgttggaa ctacgctttg
     3781 tagtgcgtag aatgactgga tggatggtag ataggtgtga tgttgtatca aatgcaatgt
     3841 tgtttatttt ggcagaagta cttacccatc tacaggggtg gaaaaactga tgtgtattaa
     3901 catgggttga gttttgaata catgccaatt gtggcaagta tgttgtttta catgctggct
     3961 tacaatggaa actactcgga aagctacttg aaagaaaact actaattcat tatgggtatt
     4021 gcgaacctgt tcattggtgc taccttttaa accgaaaaca atctcatatc ataccttccc
     4081 agcgtgaaac cccggaccac taacttacgc ctcgtagagg gtgttgagga agtccttgga
     4141 agcgcgctcg ggcttagcgg cctcaacctt ctgctggccg agcttctcct tggagaaagc
     4201 agcagcgtaa gggttgagac ggagcatgac ctgcttgttg cggagagggt tcttcttctg
     4261 gatgttggta cgcttggtgc gagcctcacc cttgggggcg cggaggacgg actggatctc
     4321 agaagagttg atgagacggg ccaggtcggc gttggcaaca acgttctggg ggaggaggta
     4381 gtccttcttg agggcggagg cggtggtggt ggtgccgtag accttgtcga gggcctcgaa
     4441 ggcagcagag gaccagacga tgaagcgacc gaggtgacca ccgggggcga gctggaggag
     4501 gttgagggag aagacggagg aggtctcaac accggggatg ttgcggaagg cacggacgag
     4561 ctccttgcca tcaacctcgg ggttgtagac aaccagagga ccgcggcgct ggcggaagcg
     4621 gcggttcctc agcttaccct taccggcacg catcttgcgg gacttctgga ccttgacaag
     4681 gtcggcaccg gcaccgacgg cctggaggag ggcaacggcg gccttggtct tggtaacagc
     4741 ggagttctcg aaggtcttgg agtcaacgac cagagggacc tcaggaacgt tggcaacgcg
     4801 gtgaccgcga gcgaacagaa gagaaggaac ggaagaagca gcgagggcag aggcagtagc
     4861 gaaacgtcta aaaagcagcc attagttcac cttctcctgg ctcaatcgtg ttacctcgtc
     4921 ggtcgggatt attatcatac ctctggccaa cgttgacctt ctggtgccac ttgcgccaga
     4981 ccttggtagg ggcgaacata cgaccggaac ggcactggtt accgaaagcg gcctgaccgg
     5041 cacggtgagt accaccaccg gagacacggg ggatacgagc gacagcgcga cctgaagtta
     5101 ttcacatcca tcagccatcc caattcccct gcgaatttct tggcgttcct tcaaatttgt
     5161 gcacataccg gtaccccagg actcagcaga ggtctgttca ccagccttct cgctcacggc
     5221 gtaaggctgt ctcttgttct tggccatacc ggtgtgcacc tgcctgtaat tcgaaatccg
     5281 tcagccatca aatatcctcc gcttctcatg attcctctct gcgagatcga ttttttgtcg
     5341 taaaaaggct gaaacatact ggacaacatc aagacggatg ggggaggcga aaacagccgg
     5401 gagggggtag gtagcccccg tgggcttgcc atcagcgccg gcgatggtga cggtaggacg
     5461 agacgccatt tttgtcgacg gtagggtggt cgttgtcgtc gttcgaggtt ggagatcgag
     5521 catctcaaga tgagcgcgca aattttcgct tagtctcacc cgcccgtcgt gggtgcggca
     5581 aagccctagc cctgttgccg ttttgggtgg gtgtttatgc ctgaggcgca aatgatctta
     5641 tcgatatgga gaaccgcggt tatacccttg acatgctact tgggcctacc cttcatccat
     5701 acaattttct ctttgattct tctgtagtca atgtagtctc gtgaagaatg tgttgcgaga
     5761 gatacacaat aaattacatg aaattctatc ttatactttt acgtgtgaaa caatgaagca
     5821 aacaatcata tttatgtcga gttcagccct gcaaagtctt gacgtctaac atcatcgcca
     5881 caacagatcg gctgacgccc agagcacaat ctgagtcgtt actgcggcat ccacttacac
     5941 cctacaagcc ctcattctat actcgtgaat acgttctaca gtcatagaac ggtaaaaaga
     6001 ttcgttggcc aacgtttatt tcatttagga tcctctctac tgcaaatggt acatgaaggt
     6061 aaacagaaat ctcaaaaagg gtcctagcac tacgccttgt gcaaggaaac gaatgtaagt
     6121 ctcaatcggt atgggctagc cacccgaatc acatttttaa tccacattta agcgtgcaca
     6181 tgtccaccgt gagcgtggcg tctggcgcgg ccctccctaa cggtacgggg cttcaacttg
     6241 atggcagaaa tggccaagtt ggagctctgt ccagcagtgc actgggtacc ggcagccaca
     6301 ttctgagcag gggtccactg gccgttcgcg cagcgctgga aagaggagcc attgatgcag
     6361 ttccactcgc cctccacact gcaagatcca gagagcgcgc cagagcttgc gctggagctt
     6421 gcgctggagc tagagctggg ttgagggctg gagacagagt tggagccaga accggagtca
     6481 gaaccagagc tagagccgct gctgccggag ctgggtgcag gagtgttcgc caccgcagga
     6541 gcagtgtagg tgtttgcggc cggggcagaa gtaaccacag cagcggccga agaactggca
     6601 gagccggagc cggagccaga gctggagcca gaaccagagt aggagccagt gctgctgtca
     6661 ccagcggcag caaaagtggg agtaccggta caggcggcgg cgccagcgga agccaggttg
     6721 ctaggctcgc cattatattg gatgtcgtca ccaggctgag ggaatcggat gtcgacacct
     6781 tcggaggtgg tgcagccgtt gacgttggcg acaaacatgg gagggaaggt ggaagagcgc
     6841 ttctcgacat cgcgcttttc ctcaacatcg gacctcttag aagaagcgct ctggacctcg
     6901 aggggagcac agttcatgta catctcacgg tttccaatgc ggttgaacca agtccaggcg
     6961 agcgtgtact tgccggggct aatgccgtcc ggaatggtgt agttgaattt ggtcggatca
     7021 gccatggaag caccaccaga aaggttaccg tccacgttgg cggggcagcc gccttcgata
     7081 gacttgatga ccatccattc ggagtccttg gtaggctgca gatcggtggt cagactgacc
     7141 tggcaggagc caccaccatg ggtggcggaa ccctcaaagg tcaaaggcat gctctcgccg
     7201 atctgggcgg tattccactc ggtgacctcg taggtgttcg agcgcagctt gcaaggaaag
     7261 tcgctgccat cggctgcaag aggcgagttg ttaagggtgt ccttgccata gggaatgggc
     7321 tcagtcatga tcatgtgtgc ttcaacagcc gaaatgccca ggagagcagc ggccgcaaga
     7381 atggacttgg aaaacatggt gaaggagcgt cggttttgtt ttgcactatt cgacagctaa
     7441 aggagtgttt gaagttctga ccgtaccgga cgagacagaa caggtggttg cgttgagcaa
     7501 aagtctagtg cagatggatt agccaagaag gagagaaagg aaggatttat atcgagatag
     7561 tgcatgatac gttggtggga agtataggag caacagacgg tgacaaccgt atagttgaag
     7621 cagtatagtg gtcgaggatg tgtagagggg caacaaggtt atggtagaca atgaaatggt
     7681 acacgggaag ataccaggat aaggcgaggt gacaatacct ttgtagaacc gaatggaagg
     7741 tgagcttgtc ccagcgttga ctttatctgg tcgaaacagg cctttgtcac gcgtctgata
     7801 ctactggaca aggatagctt cagttcgttg gaagtagaag ggaaggtcgg agtctgccgc
     7861 aggcacacaa cgaagattca aatgaaatca gaaaggagtg tcgaaagaaa gcaggactag
     7921 cctggtgata gtaggactgt cgaacagtgt agaacgaaga aaggactgaa cgctccagcg
     7981 tggttgaaga agagaaagaa gaaaagggag cagcactggc agccctgggg ggtgttatat
     8041 acttaagatt tggactgttt gaggcgccat gacggtgaat caggtatcca ggagactgga
     8101 cggatcgaga caggctgtta gtaggcgcgc accgaaagtc aagatgcgtg tgagtgggga
     8161 gggggagaag attgacagac agtgaattgg gttgcatgtc gagtcgtggg acacatagtt
     8221 ttggtggagg gtagatggac cctgagtggt ccctgacgag aagggactcc atagcccaaa
     8281 gatgaaacaa gcccgcagcg gaacctggga cttcggctaa cgacgcattt ctctgtttac
     8341 tgtgtagaat ctcagtaaat gtttccccct gccagcccat ccgtcgcacc atcagcccgg
     8401 cccgccgttt cattggctgg gcccaaggcg gttggcgccg gcatttgcca atcaacgcct
     8461 gcaggtcgcg gattcgctct gattgatcgg cttccaacta aaaactaaaa gcaaaaagta
     8521 tcatccgcca gcctagtaag tagttagaca acgttgtccg accggtcatc tcgccctttc
     8581 cacaccttcc gatcattctt tctgctcggc gaatgagcct ccaaagctcg ccattcggct
     8641 tgatcaagtg tgacccgccc actggccgaa ggtcccctgc ccttacattg cagcctttgc
     8701 ggaagatgaa gccgacgtgg ggcgatggac acagcctcgc agccactgag caaagatatg
     8761 catttctatg actctttcca aaaggcagca gcgaattgtg agtccaggcg aaacaaattt
     8821 tccttttttt cgcctctacc atgattccaa cattccacgc atacgaaata ctgtgaagaa
     8881 gtttgctctc ctgtcatcat tcctgtcccc attgaccggg aggctttcat tgtcaggctc
     8941 aacaggaccc gattgtaaga gatggcatgg gcgagaccat ccatgagata tctcattcga
     9001 ccacagaaaa accaaactaa gaatacatct ccatctccaa gatgatcctt cagcccaatc
     9061 ccaagctccc ctggcaattc cttccaccca gccatgagcg tgtgtgccga cttggcgctt
     9121 cggtggcgaa ccaaatgccc gtccatgtct taccggtgaa aatcttattg catcccgctg
     9181 ccccgtatag agcaaagcat actacaccac acaatccata cccttttttt ttttccgggc
     9241 ctgaaaaaaa ggaagcaaaa acctccgtat gcaagtggca gggaatgttg gcaatcctca
     9301 gccgccgact tttgacccaa ccaggacaca aagtaaacat ccaacctcct gcgccatggt
     9361 tcagatcatg atccccgcat ggacggaccc tgtcggcgca aaagtttggt tggatcggtg
     9421 gggttctttt ccctcccacc gttttctttc tctggcttcc tttcatcatg tcggagggcg
     9481 gctggctccg tgatctaatt gctacacgtt gataccattt actggattct tcgttgctgg
     9541 gatcatggat caaagaaagc gtagacgcgc tgcgagtcaa caatttcttt gtgcaatagc
     9601 cgcccactgt gtgcgccatg tggattcgat gcatcattgg ttacacatga ctactactaa
     9661 tagtcaatag tatgcgcgat atatttaggt aagagttgat cctaagtgac tgcatagatc
     9721 aggtcaggca caccaatcca taaaccaata aacgaaacag attagtacgc agtagtaaat
     9781 agccaagctg ctgtcctatg acgtcgtcta tcgcctccag tacttttatt cccaactcac
     9841 tcaacttcta tctataccag atcaaaaaga gacctatcta ctcaacacac aacgacagct
     9901 ccagctatac cattacccaa aattccaagc atgtgatccc gatagctact aactaatcac
     9961 cttccaaacc cagcaatagt caaccccaca aaaactatta atcacatcac caaaaaaaac
    10021 ttggcaaatt aaacccatca ccccatcatc atcaaaacac gaactggacc catcaaaaag
    10081 gtaaaaaaaa ttcaacaaag tactactcta cttcgtagac cctagatagt aagtacgact
    10141 aactccggaa gccccgaaag gatttcggca gtttcgagaa tcattgagat tgaaattgcg
    10201 gggggtgggt ggtcaggaaa tcaatctgaa acaggggacg ccggcgggag atcgcgactg
    10261 tcagctaagc gaaggggttg atgagaagat tttcgatact agtttttaat atatgatgaa
    10321 gaattatgtt tattgtctgg gggcgtctga aaattgagtc agggagttaa attatggatg
    10381 gattgttaat attgttgcct gctttagttg atatttgttg tttttgttga tgttggggtg
    10441 attgcggtgg atgatggatg ggatgatgat tattgtgatg atagtaatga atactactct
    10501 actataattg actttggaat ggtgggacac tatgtgtaac tacatagtct gagtaattta
    10561 tcatgcagta aaatgaaatt agtattgtct gattgtgagg aacatataac ataatataga
    10621 agaatgttgg cgattacatt actacagtgc ctaagccttt gcagaacgtt gaatggggct
    10681 ggaatgggtt gtgtggttcg ggccatctga cagtggatac aacgggatca tcggtaatga
    10741 atgtggactg ctggtgttct ggatcgaact cctggcttgg tcattggaac gttgtctaga
    10801 ccttctacct tgtgcagagt tgtgttggag atgctggcta atgattgcct tggaccctcc
    10861 cctcagcaag cccatcgcca ctttgcaggg caggcaccat attgagggaa taatttgccg
    10921 catgttgttg gcgtctgggc attttactga taatggagat ctgtttaatt agagggatgc
    10981 ttgcaggctg atagctgaaa gaatattggg aatgccaagc tgtggtgttt actagagtaa
    11041 gggcatggtt tcccgagata aatccgtgtt agtctaacat ccatcctcat tcatgctcga
    11101 caatgaatta tcaaactagc ccccccaaaa aaatatctct tgtacaatct tttccaactc
    11161 ggcaacccaa ttcactctat gcactcgcac tggtcggaat agagggatct gggagactcg
    11221 tttagccatt atctacaact acctcaccaa aggtaaggta aggaaaggta tgtgaaagaa
    11281 gcaacttact gggattttca gtggtgccat tatgaattgc ggttgtatcc acgccctgaa
    11341 gggtttgcat cgttagcatc ttgctgggtc caattctgat tagtgttccc acttaccaag
    11401 gtaatgtatc ccagaactct gttcgcataa tcctggccat ccagaggctc cgtgtccatg
    11461 atagtcatgg ctcccgctgt gaatcaggcc acggagtcag catctcagca gaaatcaaac
    11521 tgaaacagac atgattatgc ttactcaacg attcctcata ccagaccccg tcctgtgata
    11581 ctggcttccg cggaatctgg gtgtgatagg catacggcgg cactgccatg acttgggtag
    11641 ctacatcttc gttgaaaaac aactgtgccg tgtttaccgt tcgacttcca ccgatggtgc
    11701 cattactggt gatagtccag tcagtatgca cttgcaggtg gacatgaata gcgcggttgg
    11761 tctggggaga ttgtcagctt gcttgcgtcc aatactgatt aatgggcgtg catcctcaca
    11821 tagaatccgg ggaatataga agtaaagctg gttgcaccat tgtcatcggt cggccacatg
    11881 ccccgaagcc aagttgtatt gtccgttgct aggaacttag gttttccgtc agatgataag
    11941 aacattcttt ggaagacgtc gtcaggggag caaagggggg tattactgag gtatcacttt
    12001 cgccctcatt tttggcgggg agttgctcac cagtgctttc aaagtactgg tcctgaaatg
    12061 ggatatctgg atccaagcct gtgaaagaac tatacgatcc actagcattg cactgctatt
    12121 cctgaggtta gaacggcatt tactcttcca attactcccg tgccaatcaa acagcttggt
    12181 gaacgacagg gaagaaccgg ggtagagtga actcacccaa atatctacca atgcattgga
    12241 caagggctcg caggtatgaa tgtccataag cccaatgtct aagacaaagg gcaccccgac
    12301 ctgatcttcc acaatatcct gacgcaggac ctgactccgc ggataaatgt agggccccgt
    12361 gctagtctca ggcgtcaaaa tacaggtgtc attcttcaag aaatcatact tgggggcatc
    12421 agccgtgatg gtgtacgtgg tggtgccgct gccgtcgtcc tcagagggcg agagcgcccg
    12481 tcggcgcatt gcatgccgtt tcctcttcat gaggccgact gtgtcggagc atctcttcgc
    12541 cagtgcgcca cggcgcgcca agtggacggg atcgggttgg gcatgtggtc ctgggtgcgc
    12601 tggtggaagg agttagaatt gaacttgtga gactcggaat aggggagtca cggaccgtgg
    12661 atgaaagatg ccagcaagaa agctgagcct aaaaggagag acttcatgat gcgataaaca
    12721 agaataatgt cgtgcaggaa agtctacggg gatagcgctt gcatggattt gctgctcata
    12781 gaagaaatga aatgcttact tctgttccta tttagaaatt ctggctcggt agatggggta
    12841 gttgacagcg cagtaaacaa ttgtgatatg attatctctt gaatctcttc ggagcacgaa
    12901 aacggatatt gttaacggtc ccgatccatg gatctgcaag caaggtttca tcggaactaa
    12961 atattttcaa cgattcaatg atgtatgcta ccattgccaa agcttaaatg ggcggattca
    13021 tcttccgttc atttttcatc ttgctttctc tcggtaatga ggacattttc gctttatatt
    13081 tttttcgtaa ttcttggtac tattcttggt ttacaactat gatgtatgta tcagtgataa
    13141 gcgaagccgc cttcaatcat ctccttgaca cgcttggtac attcatcgag attttctcgg
    13201 ggcaatccca gggcatcatt agccaggcca tgcttctctc caaagttacc gtccccattg
    13261 gggtagaatt gccgcgtgta tagcatttga acatatccca gcttgtcacc cttcttcaac
    13321 cgttcctggc cttgagcata ccgttcgtgg cttggcgcgt attcaagagt ccattcctcg
    13381 tctttatcgc cggtgaccct tttccaactc tcgaatatgt ccctctggct tatcgtaaag
    13441 ctagcaatgt acagaggcct gtgcttccat gtgttcactg ttgggcttgt atcgcctgga
    13501 ccatccggca gctccttcag attcaataga gcggcaactg cacggccaca ttgatcccaa
    13561 gtactaatat taatcttagt gttcccgtta tcaataaggg tgagatgctt tctctgcacg
    13621 tcaaacccga aacactccgc tccccgagcc atactaaact cataccagaa gccacagacg
    13681 agcgcgatcc acgagcagac atttgtggcc tcgatttcct ggagagactt gcgaatcacg
    13741 tctcctctgc gagtctcctt ggccaaagcg tcgttggtga agtcggaccc ataggcattg
    13801 ggcattacat atgggaggcc ggctttggct gctgctcgaa ttaacttggc ctgagtatcc
    13861 ggtggtgcta tgacaaacat ggttattatg agaaactgtt ggtcttgcag ggccttgaca
    13921 agggttgatt catcatcgta gtcgatgtag aaaggcttca cgccttccgg caacttgttc
    13981 ttgctgcctg accgggttaa accagtaact gtgtgcttgc ctgtcctgac aagctctgta
    14041 gcgatataat gaccgatgga gccaccagcc tatgaagcat ccgagtcagt accaaagatg
    14101 tgatgattgc caagatctat gttctgactt acgccaacaa tagccacccg ttccatgcga
    14161 ttggagaagc ctggaggctg gtctttggca tactttacgg ccatgggaat gtggagtggg
    14221 gtatgacgac tgtgtctaag atgagatacc ggaggccctg aagcatcaaa ctgggctccg
    14281 agactatcag gctggaaagg gtcgaagcag cagaaagcat gaaccactcc caaggagaag
    14341 aggcagaaaa ggtaatcaaa aaagcacagg gtagttaaga aagcagcaca aggccatgag
    14401 tagtccagga gggggaagac actcacctgc tacggcccac catccttcaa tttctagacg
    14461 acttcattcc tcgttcattc ctcattcatt cattcgccac tattttccac catcccttgc
    14521 ttcggtacgc tgccacttgc cacagacttt ctgtctctat gcattagtgg gtccagtcga
    14581 tattaaatcc atagcaatga tagtcaagat gatgaaaata gtggggtgcg aatcaatgat
    14641 tcagatgacc gcaactggta aaagttgtat gctatctgcg ggtccctctg gcaatttcag
    14701 cgcgcctata tcaagcagta ctgggcctac cattaggcag atcactcata cagccactca
    14761 tgcagctcaa gtggctcaca ctggtgtgtt tgtcctcctg gccatcggcc agggctctgt
    14821 acaaccaatc cactggcttc cctgaacagg acctcgacaa tggtgtcgca ttacagcaaa
    14881 ttgccgacaa tgccctgaat aacatggagc aagagtctct gacagccaat ggttgtcgtt
    14941 tggaggacgc tcagatccgc agagaatggt aggttcattc tgcgtgcttt aaactttgga
    15001 acacggtaca aatcaaacat ctgacatctg tggtaggcgc agcttgtctc cgaatgcaag
    15061 aaaggaattc actgacgcta tcacgtgcat gcagagccgt ccaacaaata tttctgcaga
    15121 ggaaaaggag acctttcagg gagtaaaaac tcggtatgat gagttcgtag caacccacat
    15181 caatctaacg gaacacatcc atgtgacggt aagtatcgat cagtacgcaa atgatatcga
    15241 accatgagct gaagtgctat gatgtaggct gattttctcg cgtggcatcg gttcttcatt
    15301 cacgcgtttg agaacgccct gagggtggag tgcaactata ccggcactct tccctactgg
    15361 gaatggggac ttgatgcgga gaacccccaa gactctgtcc ttttcaatgg tgatctttac
    15421 agcatgggga ctaatggggt agatctgaac cggacaagca tttactgggc atctcaaaat
    15481 ataaccattc cagccgggac tgggggtggg tgcgtatatg ggggcccttt ctccaattac
    15541 actgtgcaca tgggccctat tgatgctcct ggagagcaac cggtccaata caacttggag
    15601 tataatccac gctgcttatc gcgagatgtg aatccctccg tgtctcggat gtctaactcc
    15661 tttcgcaaca ctacgaaatt gattctctcg tacgatacga ttgattggtt tcagggtgtc
    15721 atgcaggcag atcaacgttt cactgatccc actgctcctt tcagttatgg agtccatggt
    15781 ggaggccatc tcactgttgg aagtgtcttg gcagacatag ataccagtcc ggccgagccg
    15841 atgttctggc ttcatcatgc ccagattgac cgtgtttgga ccatctggca agggctggat
    15901 cctgcgaaaa gaagaaacgc gatctggggc acttcaaccc gaggcgatga cccaccttct
    15961 gcaaacatga cgttggacga ttcgcttaat tttgggttta tctctcagcc gctgagattt
    16021 gccgatctga tgaaccctct gtctggaccg ttctgctact actacgcata gcagataacg
    16081 ttttgagttt ggggatcttg attatctcgg ctccaaacag actcgcctat ccgagagatc
    16141 aagtacataa tgcaactagc tattagtcaa atataacgcc ggcagaagtc tattttgtcc
    16201 ttttctcttt ctttcctcga agaaaacccg tggattaact tgagccggtc ggcctcaaag
    16261 tcggctcaac cggcgcgttg ccaactttaa atgcagacaa ccatcgtttc cggccgttgt
    16321 gggggcgatg tagatcagat ccaaattccc aaaacatcca tggggtaaat caagaattga
    16381 ggttacatcg accgataggg ctcttaatcc aaccctcttc acggggaaaa ccttctatat
    16441 gatacatggt ttactcctct gtttctcttc ctccccggag gtgccaaatc cgggcgcatc
    16501 gtgtctattc ttagcaacca gcgaatttga caaattgatc caatcccata gaatcagagt
    16561 aactctacaa cccaatcagt cgcctaatac gcacagcaaa agaagatgca ttcggacagc
    16621 caacgcaaga aaagagatta aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaggcctccc
    16681 ctcatcacct caccaaagtc gcaatcaatc agcgaccact agctacatcg cgactgaacg
    16741 atagcattcc gcatggtgtt aaagttcaag acagttgcta tgcttgcccg aacctttaca
    16801 cattcttgcc ctttccgtag aattccaagc tcatcggaca gagagtagtg tttctgtgaa
    16861 tgtggtggtt taccaccgtt acctctgctg tctatcactt gctcctaccc ctgagcacag
    16921 gcaccatagt tacaacaccc ccacggggcc attgtctgtt ttcagcttca gcttcgtcga
    16981 caatggactg tcatatcccc tcatctcaaa agaatgtcgg aaacactgta tggcatggcg
    17041 tgtgggaacc gatcaatttg tataatatct taggcccacc tcttcccctc cgagaggttt
    17101 gacatcaggg ggtttcagag atagtccgtc gatatttatg gcttcctctg tcttcttgcc
    17161 gctacttgcg gcctcattac tgcccacact cgcttctaca cagaatgccg atacaccgac
    17221 atccgctcct actgtgcaag tccgcaatgg cacatacgag ggtctctata atcccacgta
    17281 caatcaggac ttgttcctcg gcataccgta tgcgcagcct ccggttggtg agctacgatt
    17341 ccgtccacca caaccgctca acacgacgtg gactggcact cgaaatgcaa cagcctatta
    17401 caatgaatgt atcggttatg gtagcgacga ctggtattgg accgacgtag tctccgaaga
    17461 ttgtctcgct ctcagtgtga ttcgacctca cggcatcgac tcaagcgcga agctgcccgt
    17521 cgtcttctgg atgcatggtg gagaattcgc agaaggaggc actcgcgact cccgttacaa
    17581 cctctcctac atcgtccaac aatcccagga gatgcaatct cccatcattg gcgtgactgt
    17641 caactaccgc ctttcgggat ggggattcct ctatagccag gaagtcgccg acgaaggctc
    17701 cgccaactta ggactccgcg accaacggca cgctctgtac tggctccaag agaatatcgc
    17761 ttccttcggc ggcgacccgt cgcggctcac catctggggc caaagtgccg gtgccaacag
    17821 cgtcggtctc catttagtgg catacgacgg ccagaatgat ggcatcttcc gtgccgggat
    17881 cgccgagagc ggctccgtac cctccctcgc agcatacatg agcgccgaag atgcacaacc
    17941 atactatgat gccgtcgtca acgcaaccaa ctgcaccggc tcttccaaca cccttacttg
    18001 tctccgtgaa gttcccaccg acgtcctcag ctccatcttc aacagctccc tcgtcgctgg
    18061 ggcaggatat catcccgtca ttgacggcga tttcctcaga gcctcgggga tagttaatct
    18121 ccagactggc caattcgcca aaaccccgct tcttatcggc accaacttcg acgaagggac
    18181 caagtatgcc cctcatggct ataataccac cgaccaattt gtctccctcg tccaagccaa
    18241 cggaaccaat tataccagcg ctctcaccat tgcatccctg tacccagatg acccagccgt
    18301 tggtattccg ggaacccttc aaggtcgtcc cccaccgtca tacggttacc agtggaagcg
    18361 cgtggctgcc ttcctcggcg atctgctcat gcacgcgcct cgccgcgtga caacccagtg
    18421 gctggcacac tggaatgtac ctgcctacgt gtatcactgg aacgtgatga cactagggcc
    18481 attagatgga gccgcgcatg gctatgaagt ccccttcagt ttccataatt atgatggttt
    18541 gggcgatgaa cggggaaacg acagcgtgac ctggccacaa ctatcgacta tgatgtcacg
    18601 gatgtgggtg agctttatta atcatttgga tccgaattat agtaatagtg agtgatttgc
    18661 cccacctacc tctggacact gctttaggag cttgagggta aggaaggatg ctgacacgct
    18721 gctctgctag tgacggatat ccactggcct gtctacacaa cagaaacccc gcaaaatatg
    18781 gtctttgatg tcaatgtgac tggactggct tatgttgaac cagataccta tagagcggag
    18841 ggaattgcgt atatcactag cattctgcag agtgccttta atcggtaggg tagactagag
    18901 gcttcaatat caatagatat cacacataca ggagagcagc ccatgtttcc ctccagatca
    18961 agagctattc cgttaaaagg tagtgcatcc ccgcaccggg gggaaggccg gggagtgctt
    19021 acctctgtgt gaaactagaa ttccagcaac gatggtttta gaaaggccag atctgttgac
    19081 tcattgtttg atcctccgat gttgcatccg agaaagcttc tgcttggtcg tgccaaggat
    19141 gttaacagct gctgttgagg caactctaga aaccccatag acctttacta tctcgctgac
    19201 tagagggtac agtaggtcct actttgaatt ccttggcggt tgggatttcg cggaaggttg
    19261 tctcaaccct caatgcttgt cacgacagac ggcttggcaa tgagacgaga ccacgggcga
    19321 ttgacatgtg tcaagcagta gctatcggga atctgaaaaa gcatggctgt catggacttt
    19381 gcaggcaaag gctgtctgtt ctagaccatc ggctagagcg cggtgagcat actaggcgag
    19441 ctgaaaagcc tagaagcggt tgccggttat ccgctttgtt tgtgcccttt ccgtttccgg
    19501 gcgtaggcaa tcacatttag gcaatgccgt gtgggccttg gagatctcac ctaaccttat
    19561 tgcattttac ctcacggtga tacaacctga gtgactatca gggaaactga gcctattgat
    19621 catcacatat tagcaccaca caaagctgcc aaggaacaat agtaatgtga gcgccaagga
    19681 gatatctttg aactttgtct ccagatcttg tactacatac ccagccagac aggggttcgt
    19741 atcgatggct ccacagcggg atatcatgaa tcttcatgtc gtcacgactc atacctcgag
    19801 cgatagggcc gggtattact ccatctggaa attgtcatga ctgtagagct cagctgtccg
    19861 ggatacgagc attatccgtc agtttataaa ttccagggcc atcctgctca atctcaacat
    19921 gtgggctctt acgctgtcat catattagtt agggtccaag agaatcacag aatcattggc
    19981 attgttcttc atcgttccaa atggcgcctg gaatcctgac atatctggag caggcggccg
    20041 agtattcgcc gtctaaaggc ttcgtcttct atagtgttgg taaggaccaa ccggagacaa
    20101 tcctttaccc cgatttttgg cgcctcgtca aggtaacatc cacccgcatc agtaccatga
    20161 gtcccagcag gtggtttcat gtttgctttg ctgaccgcat aattctcagc gtaatgctca
    20221 aactttagtt gaaaagaaag tcgcggtgcc tgaccgggtt ctcctggtcc attttgacac
    20281 tcacaaagag aacatcatat ggttttggtc tgtcattgca gccggatgcg ttccagctgt
    20341 gtctactccc ctagctgtag acccagtggc acgagaacgg catctaactc accttcagag
    20401 gctcctagag agacccaatg tcctcaccag tgtgaagcat acagatgact tgagtatcat
    20461 tgatgactct caaaagtttt tcatcgagga tctggcctcg aatgcagatc aatctgcaga
    20521 ttatcaacct gcgagccctt cgtcagacct tgcgctgcta ctgctcacct ccggcagtac
    20581 aggtaatgcc aaagcggtga tgctgcacca ctctcaaata ctcgccgcga ttgaagccaa
    20641 gtggaaggca ctttcaagca ctccggacaa cgtctttttg aactggattg gtaaaaatgc
    20701 ctctcaattg tgactctcca accctatgag gcgcggctaa catctcgtcg tagggtttga
    20761 tcatgttgcc tgcttcatgg agatgcacat gcacgcgtta tccaggggct gccatcagat
    20821 tcatctccca gccgtgacgg ttctggagaa ccccattctt tatctggaga agatggcaga
    20881 atattctgtc acgaacgctt tcgcccccaa tttcctcgtg gccctggtag gaaaggccat
    20941 cgaggcccaa caggagcggg atcctcgtgc acttgatctg gacttgagtc acttgcgcat
    21001 tgtgctctca ggtggtgaag ccaatctcac atcgacgagc atcatattca accgtaagtt
    21061 ggtcgagatg ggagccgcca agaatgtcct ccatccgtcc ttcggtatga cagaggtaag
    21121 cggcaccgta tgagatatgc aattggcgga cctggcccac taatactgtt gagctttggt
    21181 agacttgtgc aggcatccac tatcactaca gcttccccga acttgagcag aaggctaagc
    21241 tgcaattctg ctctgtgggg caaacaacgc ccacactgca gatgcgaatc accgatgaaa
    21301 atggggagac ggtgagaagt ggcgagaatg gaaacctgga gttgtatggg ccgatggtct
    21361 tcaagggcta ttacaacgac gacaagaaca ccaaggctgc ctttaccgag gacggctggt
    21421 ttaagactgg tgacactgga tacatcgata acagggataa ccttgtgctg tctggacggt
    21481 ccaaggacag tatcatcatc aatggaatca acttttattc tcatgagctg gagaatgcca
    21541 tagactcagc cgggctggaa gggcttgtcc cctcgtatac ggtggttgtc tcatcctggc
    21601 ttgagaatgc agacagtgaa gatgtcattg tcctatacct ttcgagccag aaaggcactg
    21661 aagacgacag aatcttcctc gaaactctta attcgatatc cagaataact gctctttact
    21721 gctccaagca gccagtggat atcataccac tcccagtaga gctgcttccc aaaaattctc
    21781 tgggaaagct ccctcgcaca aagctcaagc agcagtatga agaaggtcgt ttcagcacat
    21841 acagagatct tgccgcacaa agagcttctt cgtatcgtgc acgatccaag cgtgccccgc
    21901 agaacgacat ggaagagacg cttgctggga tctttgcaga cgaatttggc cttgatatgt
    21961 ccgaagttgg tgtggacgac agtctttatg acatgggagt gaatagcgtc cggttaattc
    22021 gatacaagag gatcgtggag actcgtctcg gcctaaccga agaaatccca atgatcacga
    22081 tcctgcaaaa cccgactatc gaagcattgg cagttatgct tcaggatctt cagaaaggcc
    22141 ccaagccata tgacccgatt gtgcagctgc aggacggccc atcaaaggct cctccgatct
    22201 tcttcttcca ccccggaatg ggcgaagtcc ttgtgttcct caacttcagc aagtactttg
    22261 ctgaccgaaa agtgtacgct tttcgagccc caggttttaa tccaggtgaa aagatgttta
    22321 ccactatcga cgaaatgaca gagtaggact cttgagaccg ccccgtcata gaagcctcat
    22381 agctgatgac cgtactagtg tctacctcaa gtccatccga gagcttcagc cggaaggacc
    22441 gtacattttc atcgggtatt cgtacggcgc catgattgct ttcgaaaccg ccaaaaaggt
    22501 cgaggcttct ggcgatagag tcggcttcct tggtagcctc aaccttccgc cacatatcaa
    22561 gaaacatatc cgagagatgg attatgccga gtcgctgctt catctcgtat acttcctcgg
    22621 gttcattacc gaagaggatg cccatcgtat gtctcctgat atgcacaagg tgagtcatat
    22681 ttataaggta atattgttcg agtaagactc ttgttaatca tcacttctag ctcccccaaa
    22741 gcgaggtcct tccagccatc atgaaagtct ccgataaaga gcgcgtccag gagctggcca
    22801 tggacgaagg aaagatccga gactgggcga tgttgtcgtc caagctccag gagctagccc
    22861 atacatatga tccttctgga actgtgcagg tgatggatgt tttttacgcc atcccgctgc
    22921 tttctgttgg tcgagacaag gatgtctggc tcaaacagca cctcatgagg tggaaagagc
    22981 attccaagtc ggttaggttc cacgatgttc ctggctccca tcatacgatg atggcagaag
    23041 agaatgtctt tgcattgcat aagattctcc gggccgcatt gaacgagcgc ggaatgcttt
    23101 gatcaaagct aggggcgtct tctcggatag tccgattacc tcttgaataa tgggaagata
    23161 gtctggatag tgggcataat cttagcggga acattcctga gcaaagatgt ttcatatgtg
    23221 atacggttag taaaaacata ctcgtattga tataagaatg taatattctt cttgcgcgcg
    23281 atgatcatgt ataagacaag agatatcact attgtagcag gggacgcatt ctaaatggaa
    23341 ggaggataca aagcagggag aagataagaa aaggccagaa aagaaagaaa gaagagggtg
    23401 gacagaaggg ttatggctga atatagtagt tgtggcgatg ggagcacacg tcgagtccag
    23461 aaatcgaaat atgccaccag tgcagaccga aacgggaagg tggcgtgtac acacagtaga
    23521 gcagcaacga agacggttct ctatccctcc gcggcgtgac gttgcaaagc tgtcatcagg
    23581 atattctatg gttccctcta atacagatag cttctttccg aagacagtag ctaattctcc
    23641 cagcttctcc acctgcgagg tctttcatct tgacttcctc tcaggtggaa tctcctctat
    23701 cagtagtcct tcgagcttct gaatagctcg cccttcgcat acttgggtag tatatcctgc
    23761 catcccattt gcgaagacgc caacctcgca actgcgagtc tcaagcctat atgtacgagt
    23821 acgcaggcca cctttatcca agggcatcta tcgaatcaga ccataggact tatcgacagc
    23881 gcacatcact aaccgcacgc ataccggccc gttcaaggag tcatcgattc cccaaatctc
    23941 cgcggaccat tttgcgtctc gtaaggagag tgcaccacaa cgggcctacc caattcacaa
    24001 gcaatagcac ctccacccac catgcttcca atcatttctt tcccttcttc tttcccttct
    24061 ccccagctgt cttctcttta acaaaacccc ccttgaccag cgcatccctt ccggccgcat
    24121 tgataatgcg aaaccgatcc ggccccagca acacaccgcc ataccatctc gtcaccacaa
    24181 ccaccacatc ccaaacatcc atcaactgca tcaaatgcag tagtcgacct ccagcagctg
    24241 tctccccatc atcatcacaa tcctgcacaa tcatctctgt agcttctcca ttcttactac
    24301 cgccagcagt agaagtagat gatttcacct cgcgaatcct ccacgcactg atattatgcg
    24361 tcgcggacgc aacctttttc tccgtcgcga gcagatgatc caggaacgcc tttgcctggt
    24421 ccagactcgt gacgtgggct gcgcgcccga cgaagacgga tttcttttcc gtgatgacgt
    24481 cggaaaggat ccatggcggt gggctagtga ggttaaatgt gtgatggtcg ggggttgttg
    24541 atcttgtggt tagcggttga tggctgccgt tttcggtgtt gagttcttcg gaggcaggtt
    24601 gggtgtggga agttgtgtca ttgttgttgg tagtggtggt tgtagcgctg ccaccaatat
    24661 tgagctccgt gaatgcctgg acggcttcat tgatcaggtc gaatagacat accgcacccg
    24721 gctggtatgt gcggctgaga atgtcctcta gtacatcgac ggcgagcttg ccctctcctc
    24781 gtgaggctgt ggatgctgtt cctaggattt tgggcggggt gtcgggatat gttgagttga
    24841 atccgaggag gaaggacaag tgagggtgtt ccggaagttg aagctttatt gttgttgaag
    24901 gaggagaaga gtctgaggag ccggagccgc cgagatcgag agttgagggg ccggtcgagg
    24961 tagaggtgtt agtgatggtg agggtgtccg gttcgtagat ggcattgatg gcttcaattt
    25021 cttccgctag atcggtattc tgcagggatt cgagggccga atccattttt gcgggatagg
    25081 gtaaggctgg gcagccctgg gtggcagcgg ggacgatggt tgacttgatg ccgcggggtt
    25141 tcaagatatt atcgcgcatt gcgctgggtc atgacggtta tcatgcgatg gagcggattt
    25201 attccgatgt ttggttctga tgtcaatctt agttgtacca aagttattgt agaattggct
    25261 ctatagctca atggtagggc gtcagttttc ggtactgaag attctgggtt cgagtcccag
    25321 tggggtcgct ttttgttttt tgggtaaccc gccccgcatt ccttaccggc gccacttttt
    25381 ggattctttt ggagcagtga ttgaccactg catataaaaa ttaaataaaa tcaaatgaca
    25441 tatatactct tttgatgcta gataacgatt gtgtttcttt tcatagactc tagggcggct
    25501 tccgtcgtgc gtaggtgaat caatttatga aagttatgcg ccaaccaaaa tagtatataa
    25561 tcgctgtcca agataatgaa tgtagattgc atggtatatt caagcaaccc agtctagcag
    25621 cccaaaccca acaagttgcc tgaacccttt gcctgcagcc tactaagagc aatctcctca
    25681 tcatccaagc catcgagatt cttccgttgc caaaacgcgc gaaatccatc taccaacctc
    25741 cgagtaatgc ccaacacatc ctccgcaggc atcgccgcaa agcacaacct gtaatatgtc
    25801 tgcgcccggt ccagaagctc cgttgtagga gcaaacatgg ttccgggacc cgaaaggcac
    25861 aaatacggct tttgcatcaa atgcagccac aaagcttgga tcagcttctc cgggccatac
    25921 ttctcaagca aggggtgcgt ctcgatgcaa accttgaccc acacaaacat accgccggtg
    25981 ggccaggaga actcgtacat ctgcatctta tccaggactt cccaggcggt ctcatcctct
    26041 gccatgggtt gtgcatcgtc ccatgcgcta ccggagtcaa tgaggtactt gccctcttcg
    26101 agaattgtac acattgtcgt catgcgttgt tcgtatcccg cacggaggcc ttccaaccag
    26161 cgaacccagc cgtccatctg ccaggcttgt tcgctctttt tagatttatt cttacttgca
    26221 cctgtggcat tctggccatc ctcggattgc tgacccacaa tcagttcggc caccatggcc
    26281 tgtacaaaac ctgatggctg ctgagttgat gtctcggtga gacgagtcag gcgttcaatt
    26341 atagctggct gagcggtaat ccatcctaag cgacaaccag gagctatggt cttcgagaag
    26401 gtgtcaagac gcacgacacg cccgtctgta tcaacggaga gatacgatgg caccaaggaa
    26461 tccagaaaat cgtacccgga ggacctgccg tgggcgttgt agttgcgtgg aattacatct
    26521 acggcatctg atcctcgaaa tccggcctcc atagcagttg cagaaggata ctgtaagttc
    26581 cagtacggat cgtcttctat gatgatgatg tcgaattgtc gacagagagc gtagatctcc
    26641 ctcctgcgct cgaccgacaa ggtcccgccc gtcgggtttt ggccgatact gcaaccagat
    26701 aaggcaacat tagccaacat gccagcaaag tgttgctaca gaggtttgaa cttacgtaat
    26761 tgtgtacatc agatgcggga gacggccctt cttgaaatcc cagttctcaa gcacgtcggc
    26821 caatcctcct ttaccatgcg caagcatacc ctgcgcatct atggctactg gaacgatgtt
    26881 aaggccccgc ggtttcacgg tttggattgc gttcatgtac acaaattcct cgcatagtat
    26941 gccctcacgt tgactgatcc aatcccgacg agggtcccac gggttagtaa aggtttcaat
    27001 ggccttggaa aacccgtcgg tggcaccgca cgtgagaagg gtgccagggc cgccggcata
    27061 ggggacattc gggtggaggt gattgcgagt gaactgccgg acgaaatcgg ccataacggg
    27121 gaggccttca gctgttccat actggagggc tgtggtaaga tcaattttct tcaggagatt
    27181 ggtagtcggg ctttctttcg ggacgattct gcgctccgtt gaaggggagc cactgggggg
    27241 cttgatctgg tcattgtcgg aggtggcggg gaaacgctga ggatgagcaa cggtagcttc
    27301 gagggtatca taggggaagt atgacgcatt tggcaggcct gatgtcgcaa gaggttaaca
    27361 aagtggcaca agtgcaaccg ccgtgttatg cccgaagcaa gagccaggaa gttagcaagc
    27421 aggagagaaa acgcaccacc agccaagttc gcaatgcctg ggatgaaaaa gtacttatac
    27481 aggctctttg tttcgctcgc ctcccgtctc ttcgtgaccg aggagaagtg atgtgacagg
    27541 tccaggggag gagacagcgt tgagtaaacc atgattatgg tggttaggcg atagcagttc
    27601 acccaagaca gccctccggg tgatactggg tttgccgtgg gaattaatgt gggaggcgtt
    27661 gcatgaatcg tcgcgaagag gatgatgaac tggcggcgac cccgatataa gcaagctggg
    27721 ggtggttatc ttggtgcttg ataagcagaa ccagcccggg ttgggggatg gtttactcca
    27781 cctggtgaac cggcgattgg acatgcggcc gcgataggct atagcacaac agacgcgatg
    27841 gctagtggct gtcattaaac gggggatcac gattcctcct tccggggagg aattagcggc
    27901 tgcacagtct ggctcctgga tccttatccg acgaatccga agacccagcg cgtgccagag
    27961 ttgctcgggc acggctggct atcaagccca gtgctgtcca tttcgtgctt ttcctgttgc
    28021 tggctccatg gacaggttcc tcgctgaact ctaaaacagc tatcacaatg ggtacaccaa
    28081 gtaatacact ttctcatgca caagtaatgg gcgagtctgt aactgtcagc cgaaagagat
    28141 gcccgtcagt gggaaagcta atcgatacta gaatagggag tagtgcgtcc cacttttggt
    28201 ccccgtcaga aaacggcttc cgtttccaga atttcttgcc ataccgcttt tgcctcgagt
    28261 cttgtgtggg gctgcgacag caaaaaccaa cattgatata cagaaagcca catacttcag
    28321 gtgacagctg gatcttcaaa cactttatag taactgtttg tatgtcacgt tattggacat
    28381 cggcaaaata agcacaaaga gccaagccaa acgaaagcaa tgacaggaac ctattttcgc
    28441 aaccgttcaa cttggagaaa tcgactatga ttgatactta gcacttgtgg attggatgac
    28501 attagagtat aaaaaaaatt atatatatat atattactat gcaatttgat tttggatatg
    28561 catatcaaac ccaatctcaa gtctcttgtg tcctatttgg tatggacttg tggtactccg
    28621 cctacttatt gccaggccgt cggtcggctc ttgcttttgc gatcggccaa cgactttctc
    28681 tgtactgcgc ctttcggtta cgctagacat agtatgaaca gacaatgtgc atgggcgcgc
    28741 actatgaagg atcacttagt tctaacatct atattatcta ccgcatctta cataaccgtc
    28801 cgatatccca tattcctaat gctctgtagg tattgagcat gctcgtgcta gttcattgat
    28861 gctgaatctt tatggctcac cgtatagagc aatgacctga agtctgttat gctgcggcag
    28921 acttgctcct tcggcgaata gcatgtccga atctatagaa gatgtatggg accggcgtca
    28981 tcagtaggga gatacatccc agcagggtaa gcgaccaatg aacacccagg ttagtgtaca
    29041 ttggaatgga cacaataacc atagctcctg cggcaatata tcgcatgaat gtcgcactca
    29101 caagagcact agcagcaaat atctcatacg tatcgatcaa atactgatag ctgcttatga
    29161 aaatgccctg caccgagaac ccgaacgcca cagatgcaat tagaggtgac cagtacgaga
    29221 cggacggata actggtccac cccatccaga aaagagatat cggaagccac ggtgcgccat
    29281 acatggcgaa ccagagtcgc tcttcgggtg gtagactggg tttgccgcta gcgatggctg
    29341 tctggagtcg tctcttataa gataggtaga catgcggaac aatggcgagt gcaatcaaaa
    29401 atcccacatt cattccaata tatgtcagtc ccactgagcc ctgtgaaaaa ccatatgtgc
    29461 gaccgtatat gaactcgtaa cccgttagaa agccgaaaag cacgatgtat acgaccacca
    29521 agtacatcgt aaaaagagct accataatct cctggaagaa tagcttgaag gggcgcgagc
    29581 agctatgcat taatcggatg ggtagggtgg tttggcgcaa ttcgatctcg gccatgaaac
    29641 gagggtcgcc ggtgatggtg cgtagttggc gagccttcca ctgcagaagt actggcccgt
    29701 aggtctcggg tacaaagaag aagatagagg ccgtaataag cccagcaagt atcagagatg
    29761 tccactctga ccaacgccag gatatgacag agctttggcc aatgaacgca ccgaccattg
    29821 gggcgagaaa aggccccaag aaagacaacg cacagcacac cggaaaggca tatgtacgat
    29881 ctagaaggtc gaagatgtcc gacatactcc caccgaatgt agtcagcggc gtgcatccga
    29941 atagcccagc aataaaacgg aatgccaact gggcgcctag atttggagat agaccggagg
    30001 ccatgatgaa aatcataaga agtgacaagg tcactaggta gacggggttg cgtcccacag
    30061 tttccgagaa aggtgctgcc acaagagatc caaatccgaa tgcaactaga taaagcgcag
    30121 tggcaagaga ctcagtcact tcactgaccc cgaacgcctc ttctccctgt ttgatgactc
    30181 cagaatcgat cgaggaagcc caccccacaa gaaagcccgt tgtgccaaca atacctaacg
    30241 tcgtccattt ctgtctcaca ggccagttct tcgggttgaa tgggtcgcct ggaccatcga
    30301 atcccactat gaagatagcc tccccgttgg tgaattcaac atcggttgca gaatgaacgc
    30361 taacgcctgg cacagtcact cttcgcccgt tctgcagcac caccccaggc attccttgcg
    30421 atgagatgga gttacgagaa gaggaaggga cagcagcgct tggacggttc gctaaatgtt
    30481 gcctgtcgag ccgagcgtct tcatagtctt caaggatgtc accagatggt tgtgaattag
    30541 gatctccagc ggcagcgggg ccgtgtatct tgatactttc gtgtaggtgt ctgcgcagac
    30601 gtcgatactg aaggaaggac tgcatattga aggcaagagg aattgaaaga tcagtccaga
    30661 gcatgcatgt tgaactggac agctagagtt gatcatattg cagatatacc atgcgtatag
    30721 cagtatccgc tttatccgct cttccgcacc acccgccttt tccactcccg ctttgcaacg
    30781 tagcgataat cttcatccga aagcatagtg aagtgtttgc atgtgggtag ccagatcaac
    30841 gcatgggtaa taatgtcctg ctagtaattg ttggaccttg taagcgggag tactgtggtt
    30901 atctccctag catgacggtc acaacgaccg ttacccatac ctcatctgcc cgccatgccc
    30961 cctgtcgtca aagagtggta tttcggcatc gaaaaaggcg ttccaatccc agtctatcat
    31021 ttctagattg tttccatcga ataagcctcc ttgcaatggc gaaccgtact cttgcgtaga
    31081 tgataagttt cgttcaaacg gtcctgagtc ctgatcctgg atgctatccc ttagaagatt
    31141 aatttcccgc tctttcttcc tttgtaacag cttgattaag gaatcgacgg tctctatagc
    31201 gatgtggaca gtaggcgtat taaagtggct cccaatagtc ttgaatgagc gcatggcgtg
    31261 gcccacgtgt gacaatgact ccttagaatc tattgcgagc aagatgcaga gaaactgaaa
    31321 gggaacattg gcaacatgcc accaaggact gcgattctca gacatacgga ccgcagcagc
    31381 agtaccgtca ctgcccattc gaatgacgca gtttatgaca tcgtttgaaa tactggaagc
    31441 agccacacgg agacgacggt atatcgtaag tgctagatta gcttgggaca gaaccaaggc
    31501 atcgtggcta agagttagac tttggacgtg atataataca tcttcaaggt ctgaaggtct
    31561 attgttctga tcgggatcca gccgctgaga aatctggaac aatgagacca gttccgcagt
    31621 caaatctccc gctcgtggca caggtggctt gcaggaaatg cctcgtaaga tgacgcgaga
    31681 cctgccatat tcatacgaga tccacgtatt tagaaccgtc gcaacccaaa atagcctgcg
    31741 ctgactttct tcatcgacac caacatccgc cgtgtcagaa tacaccagag agatcatccc
    31801 tggatcctga tgtgcccctg ctgcttcgat gatgtgcatt gcagagcagc tggccatcca
    31861 tgaggtatga ggacagccgg tgcttcgcag gtagagggta cgtaagaccc atccagtagc
    31921 atggtgtatg agtggtttat tcatagtaca ggttgcttcc aagatttcct ttgcgcactg
    31981 gaccagcgct tcttcgttcc tatgtccatt atcgcctgag taaagcgatc ccaaggccgc
    32041 aacaccgcaa agaactggat catagctgtc aaaagtgata gaattatccc agcgcagtcc
    32101 gacctttttc tctagcatat caagatcgag aacagcatat atggggtgta tacgttctag
    32161 ataatggcca acaagagcac tcatctcatc tttagagact aggctcgaga tgttagcgaa
    32221 ttgttgtatg ggctcatgtc gaagccctag gttccagctg aagccgtgca cctttggagg
    32281 gttctgcggg ttcaagctct ttcccaaaaa gtgagggaat gccgtgcctg agttcgcctc
    32341 catctgctgt tgattgacat cagcccttgc cgcaagtgct ggagaggatg ccctttcaag
    32401 gggcttggtc gaaggccttg caatgcttgg ccttgatggc ttcttccgtg gttgagcctc
    32461 gtacgcgcag tcatattcgt atttgaggca gaatgagcat ggctcatgac cgtcacattt
    32521 ccgcttacgc aacttgcagg tttcacacgc ctttttcgtc cttcgacgta tacttccaat
    32581 gggtggtcga ctggagcgat ccagagcaga ggacatgatg tcaaattagg tggatggaaa
    32641 agtaatggcg gtgaaacgga tggatgttgt tactgttatc gtgagacaat ccggaaggtg
    32701 cagcccttca gcatcggcgt tcggaaaggc aggtacccga cacgcccgct ttagcttcaa
    32761 cgtagcacac tcatttcacc cccctttcat tatcacacca caacagtttc caaatcaatc
    32821 aatcaacgct agcttaactt taattgagta tccttttgtt ttgtgagcgc tccatcccta
    32881 gttgacccat gctgatagga atggctgaaa tgatagaccg aggcggacag aatgccatct
    32941 ggcatcctgg cattgcatac aggcagacct tgattttcca accagtaata atatttgatg
    33001 agattgacct tgcatcgtct gcgacaggct cattacaaat tgaacgaagc ggaagccttg
    33061 gtagttgcta tatacagtcg atctctggct accgaattaa taaacagccg gaaagcaagt
    33121 agttaatcaa ggttcacact aagtggtgca aatgcttcgt gtacaaatta gttgataccc
    33181 taatggctga tattcaatgg ctctaatctg aatgttaata tgtaacgtaa tatttcattt
    33241 actagggtca gtccagttcc gaatccatct gctctctctg caaatcaatg actaatgact
    33301 acagttgggt gcaatcacaa accagtgggt tttctgaaca gctttacctg caggaacagc
    33361 aaggataagg ctatcctaca tgtttgctat caagaaacgg aagcttacag ggtcacaggg
    33421 atctcaggct attgagagcg accaggaagt gacagcttga acctgtaaaa tgacgaactg
    33481 gcagtgaaaa taaatgtcga tcatttacac cctgacgtcc gcctcactct tgagattaga
    33541 catcgaaggc aagggcacag gagcatagcc gccgagacgt gccgagcata ctggactttc
    33601 aagaagcgga cacactacaa tcagggagag cccagcaaga cgagactttt actagaggtc
    33661 gtcttgccac gcagctctac agacaaaccc atatgcctag cgtatgtcgc acaagcttga
    33721 tgcatagtct atgacttatt ttagcgatta tgcctatcgg agcaaggcgg atacatgcac
    33781 tatattagtg gctatccatg gaatattcca gccacgcagt cacaggaacg atcgatcaaa
    33841 catttctcca ccgcgttata ctgttatccc tagccgacga gcctacgatt gaatgttaca
    33901 cgccaaataa tgaccggata aatatttgac gatggacatt ggtttattga cccgtccgac
    33961 cgctagggat agtgggttgt ggagccaacg tgagagatta tgtatgccaa gggagatcat
    34021 tgccggatag gagggaagat cgtgctggga aacatcaact ggttcatagt cagtaactaa
    34081 gtgtatcctt gaatagaaac ttagtaagtg ggataatcga attggacaga acgtcacgcc
    34141 gaaagagtat accaacaatt cccgcaaccc gtcatttgac cacctctgaa gatgatgtcc
    34201 atgtacatac cttcacgcac accacgacgc gccctctccc aacacaaaat gccatatcac
    34261 ccactgcatg ctcaaggaat aaccattgaa catcattgga cacaattcta acttctgaca
    34321 gaaagccacc cctgactgat gatctccact tgatcctccg cagatcactc cccaatagtt
    34381 ccagaaccat ttacccttcc ccacccccag cacgcgcgta accatcttgc catgcttcct
    34441 cctcctcctc ctacctactc cggataacct ggtttggtct ggaccaggat atgactataa
    34501 ttcttatccg cttcacgtga attgcgcctc agagaagcat ataaatgccc ccctaccaac
    34561 ctaccttctt gtcccatcca tcacactcat ctctaccaga agtcccaact actctactca
    34621 ataacaccaa ttctccaagc aaaccaaacc acaaaccacc acaatgaagt tctccatctt
    34681 cgctactctc gccttcctcg gcattgctct tgcctctccc gccgctaaca ccgctacttc
    34741 tactgtatgt tattacctgt gttctttaac ttgatatctg cctgatacct atactcgctg
    34801 tgactgagtg ctaacgagag aatcctaaag cttccctccg gcgccacctg caacaaggac
    34861 ggaagcatgg gcaactgtgc cagtggactt tgcattgtga gtttcccttc tccactctca
    34921 tactttggtc tctcgggcat ctggatagag ctaacgggat gattgcgtgt tatagcaaga
    34981 ggagaatgcc agcactggaa cttgccagta aataagctgc tgggttgctt gagttgggga
    35041 tgattgctac tacctgtcca taggtggatg tacatattac tgtaatattg gggagtattg
    35101 aattgaataa agactcttga cgaggactat aatcgataca ataaacctct tactcactta
    35161 cacatgtaga acagaccttc cagagataga tgacttattt cccaccacac aagattcact
    35221 tcctagccct cccatccctc tcctcccaaa cagtccgtat caacctcaat ctgcgaagcg
    35281 catcccacaa acccgacgga atcgcaaccg gtttcttgcc cagcaaccgc ctgatctcac
    35341 cagcctaaaa ctaatatcag caacctacac ttaaaaccat aagaaaacaa ttctcaaaat
    35401 caacatacct cctcctctcc cctcgcccca caataataaa acaccccctc cccacccctc
    35461 accaacaacg accaccaaac cgcctcaacc gcctcagcag ccataccacc accgtcagcc
    35521 cacatcacct caaccggcca cggcactccc ccaaaaacca tatccacaaa tctaggcagc
    35581 acatagaccg gcgccgagca aatcgcagcg ccccaaacac tgcaaataag atcgacttca
    35641 tgcagcggac tcgccagccg tcgtccgctc gtcgtaggta tcccgtagtg gagattatac
    35701 ccgtacttgt accgacatct gtcgaaactg agctcgggga ggagaatgcc tcggaggtaa
    35761 agagtgccgg agaattcggg gtcgaggagg atgtctccgt gcggggtagg aattatgttt
    35821 gctgatgggg gtttgggtgt gaggtggagg gatacgcgga gccaggtgcg gaaggtgtgt
    35881 ggtggtagta ggagtgggat ttgggggtga gaggaagtga tggttatggt gaggtcgtgg
    35941 gctggtcgtg gttggtaggg cgtagtagtg ggagtggtgg gcttatgggt cccgtttaag
    36001 gtgttcacgg tgcaggaaag taggtttgga atttttgggg aagagtctgc gatggagggt
    36061 atgttgaatg tccagatgta tttttgggag gtgatttgga tgttgaatcc tgagcggagc
    36121 aggacgtagg ctacggcttt gagtcgttcg ttttggaaac ggaagaagaa tgtagtgtcg
    36181 tttgtgaagt tttcggtttc aggggtgtga ttgttatctg tggattgtag gaggagggca
    36241 tcggcgttga tgaacgtgat tgttcctgtt gttttgctgt agcggatgaa acccatgtat
    36301 ccgggccaag ttgggattaa ggccttcact gtaatccagt ttcgggtttc ttcgtgttcg
    36361 tggtggaaag tgtcctctac agcgaaggac ttgacgattg tttgcttcct ggtatatcat
    36421 agaggggagg aatgggaggt tagtagtgtt gatgttaaag ttgaaggtga ctgaggtgtg
    36481 gatggtagca cttacctacc agaatttata aagttctcga tacgcgtctc gagtatccca
    36541 ctccttcaca ttgtaatggt gtatgctgag ctgtgtggtc gctattgccg gaccgatctc
    36601 gtagccatta tggtccaaga gggcgtcgtc ttcagagtct agatggtcat cttcagatag
    36661 ctcggagagg tcggaaaagt ctggagctgc gtcggatgat ggttcgtaga cggctttgtg
    36721 actgggtgtg atcctaagtg gcatgtcggt gaagtgtgga ttttgtattg acgtagaggt
    36781 ttatgagata tatgtgaggt gggcttcatg caaagaaaga tggagtactg gtggatcgga
    36841 aagaaatagg tatgaatcac aagctacgtc atcttccctg taggtattcg aacttcacac
    36901 aatagcctgt agatggaggt aaaagggaac agagatagcc agaagtcaag cattgtgaat
    36961 tgttaggtat cagatctgca gtgttgggta aggtgtacgc caaaagcgaa ttcactgaga
    37021 gactaacaag cgaacaagct gcacccaccc ccactcaatt actactgtaa tgtgagcgca
    37081 atgccacaaa tctatgctct agaatcactt tggcgtacta aacaagcata ctggggttga
    37141 cattatagta ttcatccaca taatatttga caccatatct gacaagacat atctcagctc
    37201 tcatcaagag aaggccaaga caatagcccg agttttcacc tgttccagac aagggggaac
    37261 aaacagtaat tatgtacaag ttatagacat tcatacacgg agaaccgaaa caatgaaact
    37321 gcatccagag aaacgaagtc aagggaacca gctcgagaac ccccaatcca ggctagaccg
    37381 gaccaaaagg gcccaggtct tgcttatgtg cttataccat aggcattgtc aacgtacgcg
    37441 ccagtcgctt tcggtaaaag gattcccgat ggaatcaccg atgagcatgt ccgtgacgat
    37501 gacgcctatg gacatgctgg aaatgcccat ggctatgacc atcacgctta gcaggggcct
    37561 cggttggcgt ggtcacgact gttgatacaa tcttgttcac agtagatgta gaagtggaga
    37621 ctgtctcgat tccacccgtc tctgttgtga caggtgctcc gttttcatcc gtgaggatga
    37681 ggatctcctg ctcaacgtat acgatctttt gagtgacaac accttcaaca taagatgtgg
    37741 taggagtagg tgtccaggtg ctggttggtg tagttgacgt gctggtttgg aaaaagtaag
    37801 ctgaagctgc tgaagtggtc aaggttgaag tttgtgtcga agatgggaga gttgaagtcg
    37861 agagagtact tgaagtcgta gtagtagtag aaggggcacc cgcacccagc gttactccaa
    37921 tgtgaatatt tccgagatca acagtagcac cgttaagaga agcaccgata gcaatgcttg
    37981 gctcaggcaa tatcgccgag gtatgatggc cagcgttggt ataccggact gggcttgcat
    38041 acgcaggtcc atactgaatg gcgatgttat tcggcaggcc acccttgtga aggtatacgt
    38101 tctcgctttt cagctcctct ggcatggtga agttacactg agcctgctcg gtatctgtct
    38161 gaagatcaaa tatgggacaa tcttccaccc gaccagacag gttggtgcat tcatctactg
    38221 cctgttggag aaacccatat tgccagccgt agatgaagtc tccgtggtag ccgtatccag
    38281 ttgggtcacc gtttgcaagg acaaaagttc cctgcttgtt tttgaacgca taggtgtccc
    38341 agatagtttc atagaagagc gacacaaggc gggtctcgaa gccttccgga caaactccgt
    38401 ccatgactag ggatgggtag gccatgtgcg acctgtgatc ctccgagtca acatctttgc
    38461 cgttccaaca tgaagggaac atcaattcaa atcggacgcc atcagtacaa tgctcatcaa
    38521 ggaaggtctt gtttggcagg aagtggcggc ccagcgacgg ctcaggagac ttgttgtagt
    38581 ttaagcagtt gaaaccaagg gctttctggc gaagagcgtc ctgtgaggat tgattgccag
    38641 accattcgga ctttggaggg tcgggaactg gccaagggaa gttgcgtagg aatgggtcgc
    38701 cggcaatcat acggaagttc tcagggaatg ccgtcacatt ctgtccattc aggaagtagt
    38761 aactggcgag aatcggttag cgtatgactg cactaggtat tggcttcgcc actcacgcaa
    38821 gcatcccgcc cacttcgttg acaagctcag catcgccatt ctcatgcatg aagtatagcg
    38881 cgggggccca gtaagccgac ttgtcttgag tcaccccgca tgaggtacaa tccgcatttt
    38941 tcagggccgt ctcgcccgat gacatagaga aacctatgaa gccaggttta gcggaggcat
    39001 gatcatgcag acacgctgga gccagacgaa cctcctgatc cgtgaaccac atggacatgg
    39061 tctgatggtt tcccaggggc cattatgggg tcaattcgag ccacaccact tcgtccacga
    39121 caagggagac gccaaaaggc ttgggaaacg ctagaaagcg cggccaaaca ggccagaaaa
    39181 gcgacgtttt gtcgcatggt cgataatagg tcttcaaata agcgatggag atgaacgcgc
    39241 ggtagtgagt gcagtttaat gagtggattt atcgactaca cgcgtcgccg aaagtataag
    39301 tcaaggcttc aagccatcaa atgtagtaag gagtgaccag caaagaatga aaggagccga
    39361 aaggaagaaa agtcactgcg atggaaccgt caaaactagt tggtataggg aaagcaagtg
    39421 ccgacgcggg tggcagccat agtataagaa agggaataac aacaacaatg acaaagcaat
    39481 ctggaatagt tccgactgac tctggaacgg gcaccaaact gttatagcgc gctcggccgt
    39541 ccaatctgta agattggggc tcaggtagat ggcagattga aggcaagggg atcccttgca
    39601 taccaagtcc agtggctgcg ctcttcactc gccaccagcc cttcgcgtgg atgcagctta
    39661 gggcgaaggc tgatggagga ataaatccac aaaacaagct cgtgataggg agagaataga
    39721 agaaacagta gcaacttaca ttctcttccc taggataaac aagggtgacg tccgccgatc
    39781 aatacttgtc ttgttgattc cttggaatgg gactgatacc aggaatctag ggtctctgct
    39841 cagtactcag ttgcattact catgtttttt gccacgaatt attagctgga atcaaccaga
    39901 aatctttccc ttggatagcg aaaacgagcg aattgactag aaaataaaca aaagaatggc
    39961 aaaatgtcgc agaatatgga agcgtagacc agatgttaaa gagtggaagg acgtcaaatg
    40021 tcgtccataa ggcacaaaga caagtaagat cgtgataaag gaaagtgaca aaaataaaga
    40081 gcagggcagc caaggactcc tcaggagcag gaggggtaat agatactata taaaggaacg
    40141 gtccaccgat ctggaaagtt ggccatccca gtaagctact agcaatgtaa gcatggcgca
    40201 gtcacaaacc agggtcagac aatggccatg ggcccatttt tcgcacggag tgttacactc
    40261 ttcgccagct aaacatagat tccagcagat aatagggctc tcagggaaag aatttaggag
    40321 ggatcactgt cattgtcttg tggttggttg ttgggagatc tagtgagtcg acaggcctga
    40381 actctgtata attagggata ttgaagggcc cacccagctc agtagtactc ctgcctgtgt
    40441 accaagctct cgaggggtgt cgcacaatcc tatctgctgt cgctagtcat gcatcatagc
    40501 gccgatcggg tgcaggacct gcaagatgaa ctcatgtcgc atagattagt gtagtttcta
    40561 ttttcttctt atcttcatca atagaggaac attcacggag aagcgatggg ttaaccatat
    40621 cccgatggaa tagattactc gagcaccccg cctggcaagc gagtgctgct aaatctaagc
    40681 gaacgaagtc atttccccca ggaggaacca agggaggcag tgcgcctcga tgactgagca
    40741 gccctgcact cactactcct tctggttcgc tggtccgagt tgtgggagca gttcgtcgga
    40801 tgtggttggg gcatgttcag gagtgccata attaatcggc ttgtcctata aaagatgcag
    40861 atcgacgatc caacaagttg gtgtgaagga gcttgaaaca attgtttggt tagactgtgg
    40921 aggaacagcg cccggtcagc aacctggaac agggaaagcc aggggaaaca agggaccaaa
    40981 ccgccgggtg ttcctggcta acaagccact agggaggttg gctggggcct tagcgtgctg
    41041 ctgttcccgc cggtcgcagg ctgcagcttg cattatgcag atgggagatc cggacgcatc
    41101 tttacttcaa gcttatcgcg gaagcaagta ctgattgtag gttagctagt ctagagtgtt
    41161 ttattttttt ttgtagttca gctgtgccgg gtttatcgcg ggagtggttc gctttatacg
    41221 cacagcatcc tgaagatgaa acagctttct ctgtttgaca gcaatcatgg ctgatgcatg
    41281 gcgaacaatc acatcgtata gatgaaagga tggaggccag ggttattcat catcaaggtt
    41341 ataccgttag taggtagaaa acccatagga acaatacctg aagcaaacca gtttcaggat
    41401 acggtcatac tcccatccga tcgaggttaa ttaatcggag aattgagcga acctctgggg
    41461 acaaccccga ccgaggcggc aacatatatc ttgccgtcct ctacaatagt agtagtggta
    41521 ttacaacgat gatgaactaa accgagaaac attcgttgaa cgactgtcta taatgagaaa
    41581 agagaaattt atcgctagta aaaatctaac atattatcta ttcataaaca taacctgaaa
    41641 aatactacaa aacatattga accgataacc tggtacacaa tatccaagac tccgctgacc
    41701 ttgctcaatg ttgtccctcc aaataaggct tcaaagtgcc tggtgaatct ttgcggccga
    41761 ccgtcatatc attgttgtac aactccaaga tagattcttt ctcaactaga tcttgtgcga
    41821 cgctttgcaa cagataatta tattgataat gacatgaatt atcagtacgt aagcctgcaa
    41881 tatatcagcg cgctatcaat gactgtctac ctctatgtgg agttagtaca acataagctt
    41941 gaccgttgaa atgagccccc atacacaata accacaccat cgtctatgga gtaatagctt
    42001 cgaggtccaa atcgccgaca caagatagta ctctattact aaagcgaccg agcgaaagga
    42061 ctcttacagg aatggagatg ctgggtactc catagagagt aagtgagcgg tctacttcta
    42121 ccgttaatga ttcccacggt tcgattcaat ttaccgtgta gacagctaaa tactaagtgt
    42181 tcgtaacggc tgagacgacg cgtattcatt tctatttgat acgtgagtat tgtgggcatg
    42241 ttaacggatc tacgtcccta gctcaacaga caatatccgt aaaagcgccc aagaatgtca
    42301 cactcaccgt cgagagcgag tgggccgact accctgacag acagcccaga gggaagtagt
    42361 ctaaccagta gacacctata tcagcgatct ctatcaatca cctgccgctg cgcactacca
    42421 tactcgagga accggcaaac cttcccccaa aacagaaaaa gtatccataa attcggtggt
    42481 gaagccgttt cgaaaaatag acgcagctat aaagtaagat cgatggagag agaataaaga
    42541 cttactcaat gcggtaaaga gtcgtgcgtc gaaaacaatc ttatctaggc gctatccccc
    42601 agacgggaaa ggaatcctac ggccccagct tcgtggcgga tacaaaagag gcaccggctg
    42661 atgaccggcg aagtcgattg gcttgaataa ctcttacgac tatagtagtt tatgacagtc
    42721 ttcgacaaga cgtattctgc ggcgtacaca ggcatgatgt ggtgaaggga catctcggaa
    42781 gatcggaatg gtgcatatgg attttttcta acatgccgct tagttaacgt ttcaagtgag
    42841 tggctgttca tcgtgatttg tgaaatcgga gatgcctagg atgcagggta acgatcgtcg
    42901 ggtcaggcag ggtaaaacgg gcaccggaaa cttaatggcc tagtccactc ggagaggcaa
    42961 cgattgctgg ccctaagaag gaaacttaac gataggagaa gtcccaggcg gttttagctg
    43021 cgggaggatt ccgtggctga ggtccctgat gttgtgcatg caccagctcc catgttaagt
    43081 catcacatcg gtcaccagct ag
//
