LOCUS       An04                   12219 bp    DNA     linear   PLN 01-NOV-2020
DEFINITION  Aspergillus niger strain CBS513.88.
ACCESSION   An04
VERSION     An04
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Circumdati.
COMMENT     'Annotated using 1.7.4'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-03 02:41:14
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1358801
            Orig. end    :: 1371020
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12219
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[1363801:1364417](+),
                     [1364476:1364577](+), [1364646:1365341](+),
                     [1365418:1365893](+), [1365975:1366020](+)}"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(5001..5616,5676..5776,5846..6540,6618..7092,
                     7175..7219)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
     cand_cluster    1..12219
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12219
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="siderophore"
                     /region_number="4"
                     /rules="IucA_IucC"
                     /tool="antismash"
     mRNA            1191..2375
                     /locus_tag="CBS51388_003393"
                     /product="hypothetical protein"
     gene            1191..2375
                     /locus_tag="CBS51388_003393"
     CDS             1191..2375
                     /codon_start=1
                     /locus_tag="CBS51388_003393"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_003393-T1"
                     /transl_table=1
                     /translation="MLATPMTPQASHPSSSNMVCSLASTTTTTSSSSSSSSSSSSSSAT
                     QQTTISSRPKLTLQTTSLPRTFGTSSTGLSLSIAAGTASPTVRNTFKNAYEVTGPSSAT
                     ASPSSKHPSNLRFSKPSSPFTTHNPYQLPLGVKSILRNSPLEPTCRRRAGSVATTGPNG
                     GPSARRVFFPAKKQVSYRNPLEEEIQTVHYTARHSDLHDDPEPALEPQSQPQQPEVTSS
                     DEDSDSNASGCPSDTSTSEDEPETGLGKTTSSPIKRKKRKHSNAERQVRAVALMDGIAG
                     PSNPDSLTPQTPRRKRAKRRCEWRWTLGPLENRDKLLHPVQDETGPTSSASQPETIPHE
                     SETETPSSDPPLSSASTTLYHSSPSSSVSSDVETENDEWQTHTTHELECAHADQ"
     mRNA            complement(join(3513..4081,4217..4449,4506..4519))
                     /locus_tag="CBS51388_003394"
                     /product="hypothetical protein"
     gene            complement(3513..4519)
                     /locus_tag="CBS51388_003394"
     CDS             complement(join(3513..4081,4217..4449,4506..4519))
                     /codon_start=1
                     /locus_tag="CBS51388_003394"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_003394-T1"
                     /transl_table=1
                     /translation="MASFSDEGYDCSAYAAYRPSPPKALYDTVLAYHQSPRELCVDLGT
                     GHGAVARALATHFKSVLGVDSSEGMLKEAARAQQWDIIRPGGGTVAFWNWGHYVVTGRP
                     RANRALQKLFFEDLVPYWPQPGISVFNNEWMYPVECRDFANWTDLTRLVSVPANDDAPG
                     VSNTPGAIQMRASQTLGSLEILIRTLSMVHEWRKAHPEALSVREGGSGDCVDTLMRDII
                     EGEEKWRVFVTSGGNWRDIEVGLEMRSILLMARKKQFLSYCEDPHQHYP"
     mRNA            join(5001..5616,5676..5776,5846..6540,6618..7092,
                     7175..7219)
                     /locus_tag="CBS51388_003395"
                     /product="hypothetical protein"
     gene            5001..7219
                     /locus_tag="CBS51388_003395"
     CDS             join(5001..5616,5676..5776,5846..6540,6618..7092,
                     7175..7219)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /locus_tag="CBS51388_003395"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_003395-T1"
                     /sec_met_domain="IucA_IucC (E-value: 2.5e-25, bitscore:
                     85.0, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MDMYCDQFIFGHFYQLVGLPRLIVKMLQTIGIGPDPVGKDESRDS
                     AACHHIIQQTLNHLSMTGPLLGDSISPNRRRALFETTKRVLASAINDGIACATLESCNS
                     PSLLLCLRSPGGAMASDEDAWIKCGMRADAYVETDGGRVVGFVRADDLLGPVLTQNLNG
                     EISEELDPGVICGVICRWRSRQDESDAVEILVKEVRNSANNQEKWLEMASTLPILHLKS
                     SLCDWEQSVVLGHPTHPLHRTCLAQPPLVPIAPDDIPYLLEPELSFLCVPKSDMKVFGP
                     FQSLLDPLLRSLGIPKPDDTVNEIVVPCFSRQLPCITPLFPNARILGTVQNRCRAQLSM
                     RTVSMTPDVGSSPLHIKLSLNCQITSRLRTISPNAAALATAVGNILRDLLPPDLWIFEE
                     AASITGAQEDFQKACQLTCIIRKSPELRAADIGETLIPVAGLMQKPLNDYRTYMEIMFG
                     LHSLKEKQTWFRKYLIKLFSLILPPLVRHGIRIEAHSQNVLVRVNITNKEIAGFAIRDF
                     DGIRIHYPTFLRHPDNENALNDIPPGARTLTDDLHRMWHAVHHSLLQAHVGHLLYMLGL
                     ESKGGWRVVREELERALNPSRDPDGRLLYDFWLKETMLSRCFLEMRLRDAYAKFYEREL
                     PNILLRDA"
     mRNA            complement(7572..8789)
                     /locus_tag="CBS51388_003396"
                     /product="hypothetical protein"
     gene            complement(7572..8789)
                     /locus_tag="CBS51388_003396"
     CDS             complement(7572..8789)
                     /codon_start=1
                     /locus_tag="CBS51388_003396"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_003396-T1"
                     /transl_table=1
                     /translation="MLGWDVGTFHFVSDKITVQGFNHRCKIRLRTGGSSGKITRHVCHV
                     QGSNMTYDLSSEDFRRAIRLPVKHRYRSPVVFEFQQQGHHHTTAYAVYWLQHMADNEET
                     PIDIPIWVTKNGKRLTQNYITEQNCHIKRSPGLEDLHEVGRLQFHGFFSPGIDDSHEQY
                     VIDNESRETFETWEACIAQGVRERRISSDIPEDLEKLHEQSLLDGRDILKHAEPRERRR
                     WIDKQGQDWSGAFGHDPGAYLNNHGHQVAEPGRETPPHDPVNPPPTVAQSYGTMHAEEA
                     QHQNSQEQEQEEKEASSSSSETEDDNDDDHYPHQQQRVSQSTASTGGGSSSVGPPSLNS
                     IDDGALKKANKRSEERQHRGKMQWRPVRNAVFARDEAKYSLRKVKRKFTGDLAGREPDI
                     ETETGT"
     assembly_gap    8877..8976
                     /estimated_length=unknown
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     mRNA            join(10460..10595,10700..11505)
                     /locus_tag="CBS51388_003397"
                     /product="hypothetical protein"
     gene            10460..11505
                     /locus_tag="CBS51388_003397"
     CDS             join(10460..10595,10700..11505)
                     /codon_start=1
                     /locus_tag="CBS51388_003397"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_003397-T1"
                     /transl_table=1
                     /translation="MSSAEESPAQRAARLRRERREAKIKGDGAARLDKITSLSGRTPAS
                     LREETSPSPSPSPAPAAAQATTTALSPSPSPSPAPEPRTTQPSFPSQAPQQQQELDPET
                     LQAQQELFRALLRQSGQPGDSPSGSPGPQPGGPGGMGGMGGLGGEADDPTLKLLSSLMA
                     GDTSALGEGSLPGGQSPADLLTGLGVPPFVASMLGEATRKKSDEEKREILVWKVLHVVF
                     SVLIGVYLLVLIGSSVATFGSQPPPPATARNPFLFFTTGEVVLTGARVMMKRGGGGLGL
                     WVQLVRDIARDGSIVLFLFGMANWWHREWTAN"
ORIGIN
        1 tgattgtgac actaacccaa agagggtgtc acttccccac agtcactcgt gcagggacta
       61 tgccattttt agaacaccgc gtcagctgca gttctgattg gtctgtgcaa gatgcaactg
      121 ccttacgtaa gggcggtact gtgacgcgca ccttttcctt ttccctgctc cagttgattg
      181 ctataaataa cgtctcgcaa ctcgtgcccc cagaatgact aaccagcaat tttccaacgt
      241 ggaaagaatc aaaaacacaa tgactctgat gatgtgagtc aacactaggc aaattttcca
      301 gcagagacat tgcggagatc agactgctgg agggatggat cggccgcgtg tctcgcccgg
      361 gcgtcgatgg ccagaagatg gcagatggaa tggagccgtt ggtaggatcg gccattctcg
      421 atcatcagaa aactggggcc cgtcggcggc ggcgtcaata gttgggttat aattagatga
      481 ggagcgacta gccggccggt ggtccagcag aggagcactg agactttgaa gacaatgctg
      541 aatggagatg ctgagggtgc gatggagtcc agcgactcca tccaggccgg gttggatgat
      601 aggatggcga agactcgtaa atttagcact tttgattaac agtaatctct taatttctta
      661 atttctttaa tttccctccc ccgcggctaa ggaaatttca ttttcattta acccagtttc
      721 ctctggactt tactattcga tcttctattc tctgcctatc ctctgcttat cctctggttc
      781 tacagttcat ttcttcaaca ttccagcaaa ccatgagtcg cagatcattc taaaataagg
      841 cgaccctcgt acaagcgccc acgtctctcg tctgcttggt tccagtcgtt gggatcccac
      901 ctggtcttat ttcagaacct tatcgtccct ggatttgacg cgcttggtgc cggtcgttgc
      961 acttctgcat cttgaatcac actccggtgc tgttggcaag gcgctactgc ttctgcttcg
     1021 tctttgctgc ttcttggtgc ggggccttac tgttgcaccc ccaagacctc ctcgctttct
     1081 ggtctcattt cgtttatctc ctccttcctc tcttcctccc tcttcttctt cctcttcttc
     1141 ttcctcttct tctactgctc cctccgccgt tgtgtttggg ggctttcgcc atgctcgcaa
     1201 cccccatgac cccgcaagct tcccaccctt cgtcctccaa catggtctgc agtctagcct
     1261 cgactacgac caccacctcc tcttcttcct cctcctcatc atcatcctcc tcctccagtg
     1321 ccacacaaca gactacgata tcgtcccgac cgaaactgac tctccaaacc acctctcttc
     1381 cccgaacctt tggcacatcc tcaacggggt tgtccctctc tattgcagcc ggaacggcat
     1441 ctcccactgt ccgcaatacc ttcaaaaatg cctacgaggt caccggccct tcatctgcca
     1501 ccgcctctcc gtcatcgaaa cacccgtcca acctccgctt tagcaaacct tcctctccat
     1561 tcaccacaca caacccatac caactcccac tgggggtgaa gagtattttg cgaaactcgc
     1621 cgctcgagcc gacctgccgc cgacgggctg gatcggtggc caccaccggg ccgaatggtg
     1681 gaccgagcgc acgccgcgtc ttctttcccg ccaagaagca ggtcagctat cgcaaccctt
     1741 tggaagagga aatccagacc gtgcactaca cggcacgcca ctctgatcta cacgacgacc
     1801 ccgaacctgc acttgagcct caatctcaac cccagcaacc agaggtgacc tcatcagacg
     1861 aggactcgga ttcgaacgcc agcgggtgtc cctcggacac cagcacttct gaagatgaac
     1921 ccgagaccgg cttagggaag acgacatcgt ctcccattaa gcggaagaag cgcaagcatt
     1981 cgaatgccga gaggcaagtc cgggcggtgg ccttgatgga tggaatcgcg ggacccagca
     2041 atccggacag cctgacaccg caaacgccgc gcaggaagcg agctaaacgt cgctgcgagt
     2101 ggcgatggac cctgggcccg ttagagaatc gtgacaaact gcttcacccc gtccaggatg
     2161 agacgggtcc aacatcatcc gcgtcccagc ctgaaacgat accacacgag tccgaaacgg
     2221 agactccgtc ctccgaccct ccgctgtcca gcgccagtac cacactctac cactccagcc
     2281 ccagttcatc tgtctcgtcg gatgtggaaa cggaaaatga tgagtggcag acacacacga
     2341 cccacgaact tgaatgcgca catgccgatc aatgacgata acccatgctt ggttacgaac
     2401 ccccttgcat tgatgatcac gaattatgca tatagacggc agatgaacca cagcataccc
     2461 tatcctactt ctagacattg ctagatagct attattgatt tgggaagatt ctttcttttc
     2521 ttttttctgg tcgggaagct gtactttgaa tgtcaggacg ttcatgccat ttacattcac
     2581 cgaccagtca tttttattac acttctgcct actttctcta taaatatttc ttatatcttc
     2641 ttccaataat atatacttat gcatactatg aatgcaattt gaccagatga tcacatggct
     2701 tcattccact ttctcctatg caatgtttgt actacgtgcc tgctgtatgc tcctgcagct
     2761 gcatgcttca tacaaatcat aaatacgatg gccgatctct gatgcattcc ccatcctctg
     2821 cttattatag caacaataat aacatgcgga gaccccatga tattaacttt cgtggatctt
     2881 cattgcgtca ttatgtccaa cgaatctctc tagtaatagc tgcatcgact tgcagatcat
     2941 tctccagata gatcttatga tgccagctag tcagccagcc agcccttaga ctttgctagc
     3001 ctactaaaag gtgtgtagta tacgtagaga aaaaaaaaca aagaaaaaaa taaaataaaa
     3061 taaaagtgct cgtagtctat taccagcatg gtcaaaaacg gactatctgt cttagcagag
     3121 acaaccgtgt aatgactgta tacctgcttc tctcgcatga gatcatgttg aactcctgaa
     3181 aggttgacaa gaaaatgcaa ataacaacgt aagtctatgg ggtaacagat aaataaaagg
     3241 tgaatcaagg gatagaactg ctaacactcc acgaacaggg gaaaccacgt gtagcacctg
     3301 acctgctaag cagcagcagc gggccgctcc agcatcttct ccctacatac tttcttctcc
     3361 agaactttgg acctccatcc ccgattattg aatatcatag cacttccgca agactcactg
     3421 tccatacatt gcgatctgca aaacctttcg gaacgcatat gttttgtata gacccgtcct
     3481 gcacgggata atcgaaaggc ggatgcatgc tatcatggat agtgttggtg cggatcttca
     3541 cagtatgaca ggaactgctt ctttcgagcc atcagcaaaa tgctgcgcat ttcgagacct
     3601 acctcgatgt cccgccaatt gccccccgac gtaacaaaga cgcgccattt ttcctcaccc
     3661 tcgattatat ctcgcatgag ggtatcaacg cagtcaccag acccgccctc tcttactgat
     3721 aaagcctcag gatgtgcctt acgccattca tggaccatac tcaatgtccg tattaggatc
     3781 tccagactcc caagggtctg tgatgcacgc atttgaatag ctcctggagt gttggagacg
     3841 ccaggcgcat cgtcattggc agggacactt accaaccttg taaggtcggt ccagttagca
     3901 aaatcccggc attcaacggg atacatccat tcattgttga acactgatat tcctggttga
     3961 ggccagtacg gtaccagatc ctcgaaaaac aacttctgca gggcccgatt cgcccgcggg
     4021 cgtcccgtca cgacgtaatg accccagttc cagaaagcaa cagtgccccc ccccggccgg
     4081 actattcgtg tcatctcatt ccagagcggt tcagggtcga actaatgcgc tgcttgacgg
     4141 gcgattacca gatcaaccgt cttcgatgca atgaagggga gagactatgc attggactgg
     4201 tgatattgga tattactgat gtcccattgc tgagctcttg cggcttcctt cagcatcccc
     4261 tcggaggagt caactccgag gacagatttg aagtgcgtgg ccagcgcgcg agctacagcc
     4321 ccgtggccag tccccaggtc gacgcatagt tcgcgtggag actggtggta ggctaaaaca
     4381 gtatcgtaca gagccttggg aggggaagga cggtatgcag catatgctga acagtcatag
     4441 ccttcatccc tagtgcagca gaaaatgagt atgttgaaaa tagtgatctt tgggggacaa
     4501 ctcacgagaa actagccatt attgaatgtg acctaccctt ctgccgatta tattatcgga
     4561 ctcgaattct ttctttgctt tttcttttga tgtcattgca gaggttcaga gatggttcat
     4621 atattatact aacttatgac ttgaatagtg atctgtcata ccctcctatg gctcttatgc
     4681 ataaagtatg cagcactgcg tgcaagcctc ctaagataag atgaatgctc tacataaaca
     4741 atttccatga caatgttatc tttatcgaac atatctagtt cgatctggcc caataaaggt
     4801 tatcatcttg aaccagtagg attcccgagc gatgttgcat ttcggccttt tccgcggaag
     4861 ggagacttcg ctgaatgcaa catgtaacag ccctactgga atctatttcc gcttagggat
     4921 tccattgatg tcaccgatct ccggccaatg ctggggattt tagccctata tatgcttata
     4981 atgtggacta cgcctttaca atggatatgt attgcgacca gtttatattt ggccatttct
     5041 atcagctcgt cggacttccg aggcttatcg tcaagatgtt gcagaccatt ggaataggac
     5101 cagatccagt gggcaaggat gaatcaagag actcagcggc atgccaccat atcattcagc
     5161 aaaccttgaa ccatcttagc atgacaggac ccctactagg agactccata tcgcccaata
     5221 ggcgacgggc gctctttgag acaaccaagc gagtacttgc cagtgcgata aacgatggca
     5281 tagcctgcgc aacccttgag tcatgtaaca gcccgagtct gctgttgtgc ttacgcagtc
     5341 ccggaggagc catggccagt gatgaagacg cttggatcaa gtgcggtatg cgagctgacg
     5401 catatgtcga aacagacggc ggcagggttg ttggatttgt gcgggcagac gatctccttg
     5461 gacctgtgct aacccaaaac ctcaacggcg agatatcaga ggagcttgac cctggtgtga
     5521 tttgcggtgt tatctgccgc tggcgttctc gccaagatga aagtgacgca gtagagatac
     5581 ttgtaaagga ggtgcggaat tctgcgaaca atcaaggtga actaacagct actttcaatc
     5641 taacccttca aaaacaagaa ctaatgttga gatagagaag tggctggaga tggccagtac
     5701 tctgcccatc cttcatctga agtcttcact atgtgattgg gagcaatccg tcgtattagg
     5761 acaccctacc catccggtat cacttctacc ttttcttcga tttgccctaa tctactcgcc
     5821 tttggcttag ttaaccgtat tgaagctaca ccgaacgtgc cttgcccaac cacccctagt
     5881 tcctatcgcg cccgatgaca tcccttatct actagagccc gaactatcgt tcctctgcgt
     5941 tccaaagtca gacatgaaag tcttcggacc attccagtca cttctggacc cactcttgag
     6001 atcactcggg attcctaagc ccgatgatac agtcaatgag atcgtcgtac cgtgtttcag
     6061 tcgccagctc ccatgtatca cgcccctatt ccctaacgca cgcattctag ggactgtcca
     6121 aaaccgctgc cgagcacaac tctctatgcg gacggtctct atgacgccgg acgtgggcag
     6181 ctctccgtta cacataaagc tatcgctgaa ctgccaaatc acttctcgtc tgaggaccat
     6241 ttctcccaat gctgcagcct tagcaactgc agtggggaat atcctaagag atctgcttcc
     6301 cccggattta tggatcttcg aagaggcagc ttccattacg ggtgcccagg aagactttca
     6361 gaaagcatgc caattaacat gtattatccg aaaaagtcca gaactgagag cggcggacat
     6421 cggggagaca ctcatcccag ttgcgggact aatgcagaag ccgttgaacg attatcgaac
     6481 gtacatggag attatgtttg gtcttcatag cttgaaggaa aagcaaacct ggtttagaaa
     6541 gtaagtgata tactataccc cattcatata ctagtaacct ctatctttat ttaacgaaac
     6601 gacctaataa aacaaagata ccttattaaa ttattctccc tcattctccc ccctctagtc
     6661 cgccacggaa tccgcatcga agctcatagc cagaatgtcc tcgtccgcgt caacattact
     6721 aacaaggaga tagccgggtt cgctattcgt gactttgacg ggatccgaat ccattatcct
     6781 acgtttcttc gccatcccga caatgagaat gccctcaacg acattccccc cggtgctcgc
     6841 actcttactg atgatttaca tagaatgtgg cacgcggtac atcattcgct ccttcaggcg
     6901 cacgtgggcc atcttttata catgttggga ttagaatcga agggtggatg gcgtgttgtg
     6961 cgtgaagagc tagaaagggc tttgaaccct tccagagatc cagatggtcg gctactgtac
     7021 gacttctggt tgaaggagac gatgctgtcc aggtgttttc tggagatgcg gttgcgggat
     7081 gcttatgcga aggtgggttt gggttttctt ttctgtgtag tgatttttcg taggtctttg
     7141 agtgttggat aggtcgctga tgctgaacaa acagttctat gagagggagt tgccgaatat
     7201 cctcctccga gatgcttgat ttcgtgtcta gtattactcg aatctaaagt atatttcgag
     7261 tacatacaac aatataatat gcatgatcaa acgctccatg ttaatgctat tcaagaagat
     7321 ctatcttgcc catatttcga tgatcctccc tcctactcgt caggttttat tctcatcaat
     7381 aacccccaat tgccgaattc tgcacgacta ttgtactact atgttgatcg tttcatatgc
     7441 acactaattt tgacaatgca atacaatact aatgaaaaac taaatgaaga gctaagtact
     7501 atacatacac atcctatcat tcaatcatac acacgtacac atatacattt aagaaagcat
     7561 aaggacctaa tctaagtccc cgtctccgtc tcaatatccg gctcccgacc cgccaaatca
     7621 cccgtaaact tcctcttcac cttccttagc gaatacttag cctcatcacg cgcaaacact
     7681 gcattccgaa caggtctcca ttgcatctta ccgcgatgtt gacgctcctc gctgcgttta
     7741 ttcgccttct tcagggctcc gtcatctatg ctgttgaggc tggggggccc gacactgctg
     7801 ctcccgccgc cagtggacgc tgtactttgt gagacgcgtt gctgttgatg ggggtagtga
     7861 tcatcgtcgt tgtcgtcctc ggtttcgctg gatgaggagg atgcctcttt ctcttcttgc
     7921 tcttgttctt gggagttttg gtgctgcgct tcttcagcgt gcatggtgcc gtaggactgg
     7981 gcaacagtgg gcggcgggtt caccggatcg tgaggaggtg tctcgcgtcc cggttcggca
     8041 acttggtgac cgtggttgtt aaggtaggcg ccggggtcgt ggccgaaagc gccgctccaa
     8101 tcttggcctt gcttgtcaat ccagcggcgg cgttcgcggg gctcggcgtg cttgaggatg
     8161 tcgcggccgt cgaggaggga ttgttcgtgc aatttctcga gatcctcggg aatgtcggaa
     8221 gagatgcggc gttcgcggac accctgagca atgcaggctt cccaggtttc gaacgtctcg
     8281 cgggattcgt tatcgatgac gtattgttcg tgggagtcgt cgatgccggg gctgaaaaag
     8341 ccgtggaatt gcaggcggcc aacctcgtgt aggtcctcga ggcccgggct gcgtttgatg
     8401 tgacagttct gctcggtgat gtagttttgg gtgagtcgtt tgccgttctt ggttacccag
     8461 atgggaatgt caatgggggt ttcttcgttg tcggccatgt gctggagcca atagacggca
     8521 taagcggttg tgtgatggtg gccttgttgt tggaactcga agacgacagg tgatcggtag
     8581 cggtgcttga cagggaggcg aatggcgcgt cggaagtcct cgctggagag gtcgtaggtc
     8641 atgttagatc cttggacatg gcacacatga cgagtgatct tgccgctgct gccgccggtg
     8701 cgaagccgaa tcttgcagcg atggttgaag ccctgcacgg tgatcttgtc ggaaacgaaa
     8761 tggaaggtac cgacatccca gccgagcatt tgcgggggca gtctggtctc aacgtgccgg
     8821 aaaagaatgg agatgcgaat acgtccgaat ccgatgccgc cagtgagagg gtaccannnn
     8881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnncatg ctatcccatg aagcaggtgt
     9001 tgtggtgagt ccattcctga ctagaaacta cagcatgctg cttgctacct taactagcct
     9061 ctgatcacca gaggcacacc tgcacctcga ctgagccaca attttgtgat atagcaatac
     9121 tcacgatgtc agtttaacat gtattacagt gagaatcatt gctgcaataa catccatcac
     9181 ttgactgccc aggcaactgc tgagatccca atcttgattt attgcaaata catgacttct
     9241 gggaacagcg aacaaccatt gtagatcttg tagctttact cttggtcagt tattgccaga
     9301 tcctagttct gagtgatgtt ggtctctatt cctctcatta aaaacgcgcc ttgtcctccc
     9361 cggacgcgtt gttggatctt cgattttgca tcaatgcccc atagaatgct caaaataaga
     9421 tattaataac caggctgaaa gtgagcaaat gtggcacaat ccaaatttac tgatcaatca
     9481 ctgacggtac aaacttggcg ggctctcaga agaagggtgg ctacctgctc agcagtatgg
     9541 ggcctctaaa aaggaacgaa tccttgatgg ccgaaaactc ttaagggcgc cagtccagat
     9601 gagctagaaa agatgaagca aggtcggcca tttcggaatc acgaaagtcc ttctagctta
     9661 gacacttgta tcaatcctac tagcaatcgg tcttgtagtc attggccaaa tggtaatgct
     9721 tttggtcatg aatccttctc atagaaggcc aagatatcaa caagatcact catcattgag
     9781 tttcatacta atactatgca ctactaagta tgctttctat caatacagtg gttgcactac
     9841 tagtactcca ttctggatat attctgagca ttttaccaca attcagtaac gaacttggcc
     9901 caggaagctt ggacggagat tgaagatata tttaaacatc ctaagctagt acttactgac
     9961 ggtaacacgg aatgcacact ccatggtact actactacta tgaaccagaa tctctgattc
    10021 aaaccatgaa cagctataac atctacacac aagcacccaa atgccaccca aaccctctcc
    10081 ccccacaagt agcaccccat aaagctatac accagcatca cgtgactacc acatcaccag
    10141 cggagccggc cgttatgcgg ccaccacatc acagataatc accgattacc gccgccgcaa
    10201 caatctgtgg ctcaattcac atttccctcc acattcacct caatccctgg agcgatctcc
    10261 aatcgctctc acagagctat tcgtcctaac aatttaccag aaagacatcc acctttgctg
    10321 gcgccataac agcccaaaca attcaaccag accgattgaa cttacgtcac ccaaaacatc
    10381 tcacgacaga agtacagcca cacgaccaac aaacctcaca agaataaaaa aaggaggata
    10441 agataaaaga ggaagaacca tgtcctcagc cgaagaatcc cccgcccagc gagcagcccg
    10501 cctgcgccgc gaacgccgcg aagccaaaat caaaggcgat ggagcagctc gtctagacaa
    10561 gattaccagt ttgagtggac ggacacctgc tagtcgtatg taccacacta ttcaaccccc
    10621 ccccttatac aatcttaagc gaaaggaaca aagataatat gataatgaaa ctaacgaaat
    10681 ccttcttgct acgtattagt ccgcgaagaa acctctccct ctccctctcc ttctccggct
    10741 ccggccgcag cacaagctac cactacagca ctaagcccca gcccgagccc aagcccggcc
    10801 cccgaacccc gaaccactca accttccttc ccaagccaag ccccccagca acagcaagaa
    10861 ctcgaccccg aaacgctcca agcacagcag gagctcttcc gcgccctact ccgccagtct
    10921 ggccagcctg gcgactcgcc cagcggaagc ccaggacccc aaccaggagg accaggaggt
    10981 atgggaggaa tgggaggtct aggcggcgaa gcggacgacc cgacgctgaa acttctctcg
    11041 agcctaatgg ccggggatac cagtgcactg ggcgagggct cactgcctgg aggccaatcg
    11101 cccgcggact tactgacggg gttgggagtt ccgccatttg tggcgagtat gttgggagag
    11161 gcgacgcgga agaagagtga tgaagagaag cgggagattc tggtgtggaa ggtgctgcat
    11221 gtggtgtttt ctgtgttgat tggggtgtat ttgttggtgt taattggttc gtcggtggcg
    11281 acgtttggga gtcagccgcc gccgccggcg acggcgagga atccgttctt gttctttacg
    11341 acgggggagg tggtgcttac tggggcgaga gttatgatga agaggggggg agggggttta
    11401 gggttgtggg tgcagttggt tagagatatt gcgagggacg ggagtattgt gttgtttttg
    11461 tttgggatgg cgaattggtg gcatcgggag tggacggcta attagatagg gagtacgtag
    11521 tactctctag tgatcagggg actgggtttg gtcgtgggta tcttttcttc tcttgtggat
    11581 tatggcatag ttgtttcatg ctgtgcttat gaatacattt tgcagttctt gcatattgca
    11641 tgtgaaaatt gttgacataa catatgatcg tctgatgctt gctggggcgg ttcttttgcc
    11701 atcgactata ctaagcggca taagtgcagt cgcagctccc acgtgcttga atgcaaatgt
    11761 ccaaaagtac ggtgggctag gggacacact tacgtgcgag atatattggt ccccccttca
    11821 accctgtact atcatcgtag gaacttggtt ctggcccggt tgatttctcc tccggactcc
    11881 gactggcctg tgcgctcgct cccagaaacg aggttgatat tagctgtgag aagtgaaaac
    11941 ttctcgcagc cattaccaat gtctcaccga acttggccac agcacaacgc gtactgatcc
    12001 atcgggtgaa ctaaggaaat caataacggg caggccaaga cgttattaat ttgcacttgc
    12061 aggggggcct attgggacgg actttcctac cgccgtgttt agttgatgca ggacgggcca
    12121 gaaatccgcc gtctctaacc atccgagcct acaccggttg gctcagcaaa gtgaccacta
    12181 aagactggcg gcgggctcag acgtcgaaat ggtagaagc
//
