LOCUS       An09                   22317 bp    DNA     linear   PLN 01-NOV-2020
DEFINITION  Aspergillus niger strain CBS513.88.
ACCESSION   An09
VERSION     An09
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Circumdati.
COMMENT     'Annotated using 1.7.4'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-03 02:41:14
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1476669
            Orig. end    :: 1498986
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22317
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[1486669:1487340](+),
                     [1487400:1488846](+), [1488895:1488986](+)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(10001..10671,10732..12177,12227..12317)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..22317
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22317
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            join(5122..5161,5220..5940,6020..6140)
                     /locus_tag="CBS51388_006380"
                     /product="hypothetical protein"
     gene            5122..6140
                     /locus_tag="CBS51388_006380"
     CDS             join(5122..5161,5220..5940,6020..6140)
                     /codon_start=1
                     /locus_tag="CBS51388_006380"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_006380-T1"
                     /transl_table=1
                     /translation="MSHHMEDAHKRPKGILKNSSSQVPQVAQHAHATLTIPSTSADPTD
                     TKELTLQNTLQNAGRRRSSSNTRPGSSSRRQSLASIHGHHDDSSPRLKWDEANLYLTEQ
                     EKTAKMKIDEPKTPYAPRYDPAEDEDELAGEESLIDAQDIVVDELDKTKKAPKKTVAED
                     DIPELELGEAEEYGGDAHMGDADRIVRERSLSNDSHRGGKHVVVGAGELNGETESGGDT
                     LMTAGEAEEKHRQFEQHRKKHYEMRNIKDLLAHPEDLEDEMDEDEDEGDSSSAAVPPPM
                     PRIPERFLNGGK"
     mRNA            join(7875..8638,8702..9371)
                     /locus_tag="CBS51388_006381"
                     /product="hypothetical protein"
     gene            7875..9371
                     /locus_tag="CBS51388_006381"
     CDS             join(7875..8638,8702..9371)
                     /codon_start=1
                     /locus_tag="CBS51388_006381"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_006381-T1"
                     /transl_table=1
                     /translation="MADQPEKTAAAPAAPEAQPPTTATTTTEPAVSESQTQPEPQPEAE
                     QKVEQATTGEEASPAPAATEPPVTEPTPAPAQEAPEDKKEEAPKEETKETKAEESKEEQ
                     KAEEPAAEPKAEAAKEEEQKPAQPEYLAKNPALSQFFDRLSAILSSTGHNEMWGVTLKD
                     SSDVPTVNILIKFLRANEGNVKLAEEQLTKALQWRKEMNPLALTEGRYSAERYGGLGYV
                     TKYPEANGKETIVTWNVYGNVKSIDQTFGDVDGFIKWRVALMELAVKDLKLSEATTVID
                     YDGEDPYQMLQVHDYQNVSFLRLNPTIKAASKKTIEVFSMAYPELLREKFFVNVPAIMG
                     WMFAAMKVFLSKNTTRKFHPISNGANLAREFPSLKDKFPKTYGGNGATLEEDAFTVNLE
                     KAEPAPEAPKEEPKEESKQEQAEAPKEEAKAEQAEAPKEEVKEEAKEEAKTEQPAAEEP
                     AKAEAAVTTQEAPAAAEAK"
     mRNA            join(10001..10671,10732..12177,12227..12317)
                     /locus_tag="CBS51388_006382"
                     /product="hypothetical protein"
     gene            10001..12317
                     /locus_tag="CBS51388_006382"
     CDS             join(10001..10671,10732..12177,12227..12317)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: terpene_cyclase"
                     /gene_kind="biosynthetic"
                     /locus_tag="CBS51388_006382"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_006382-T1"
                     /sec_met_domain="terpene_cyclase (E-value: 1.4e-15,
                     bitscore: 52.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MSGSHIGPWRTPAQGHLTPDANGDLKTDYTRWRLRDDRGRQTWHY
                     LESDAENEQWPQSIADKYFLGLPTGLPELPKPQTPLQCAENGLEFFSKLQLEPGNWACE
                     YGGPMFLLPVLIITYYVTKTPIPPEYATEIKRYLFARQHPEDGGWGLHIEAHSSVFGTC
                     MNYVTLRLIGVSEDDPRMIKARGLLHQFGGAIYGPHWAKFSLAVLGVMDWECVNPVPPE
                     IWLLPDWVPFAPWRWWIHIRQVFLPMSYLWSKRFSHPLDPLTKQLRQELYTQPYDSIDF
                     AAHRNSIHKADNYYPKTWLLNTLNSLLVNIWNPYLRVPAIVRRAEEWTWELVRMEDENT
                     DYAGLGPVSNPFNMIVCYEHDGPDSYSVRRHRERLHDYMWMKDEGMLMNGTNGVQVWDT
                     AFITQSIVVAGFGDDPKWRPMLTKALEFLEDHQLRENVPDQEKCYRQHRKGAWPFSNKT
                     QGYTVSDCTAEGLRSTIQLQEMHNFPKLISEERLKDSVDCLLLMQNPTGGFTEYETTRA
                     SEKVEWLNAAEVFGGIMIGYDYPECTTASVTALSLFSKYYPNYRAAEIKSAKEKAVQYI
                     KRVQRADGSWYGSWGICFTYAAMFALESLASIGETYETSADSRRGCEFLISKQKEDGGW
                     GESYLSSEKHVYVQHEKSQVVQTAWASLALMEAGYPHKEPLRKAMQLLMSRQQANGEWL
                     QESIEGVFNQSCMISYPNYKLYWPIRALGLYARKFGNEELV"
     mRNA            join(12730..13527,13583..14173)
                     /locus_tag="CBS51388_006383"
                     /product="hypothetical protein"
     gene            12730..14173
                     /locus_tag="CBS51388_006383"
     CDS             join(12730..13527,13583..14173)
                     /codon_start=1
                     /locus_tag="CBS51388_006383"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_006383-T1"
                     /transl_table=1
                     /translation="MNAASLGDTALQQSDPHTATIHYTTALLTHPRSPSYFIKRSTAFS
                     RLKPTPNLSAALRDAESAVLLARERGKRELIVEAQMRRAIVLFLMGRYVAAEGVVGVVE
                     GMIGLDKDGNGGEDKEEKVRKAMGGGAGKGIEAEVRIWGAKIRAKVNGLGEQSGERGEK
                     VEEVPVGVKVPGEKELRGQLEELRGGKVGEGIGGEEKQSQKVEDKVEEKERAEVKETQQ
                     QQQQQQQQVKVRHEWYQSGETVVVTLYVKGVPKDKVAIELKEDSTSIQFPLPSGAEYDF
                     TLDPLFAPIDPSTSKVSVFSTKIEISLRKKTPGQKWSALESTTGPVISTPQPTVTPTTT
                     TTQAQAPSYPTSSRHGAKDWDKLASSLTQKSKKDKTKSSSKPKDEQGEGEEDDGEASDA
                     ESINSDFGGGDAVDGFFKKLYANADPDTRRAMVKSYVESQGTSLSTNWDEVGQGPVKVR
                     PPSE"
     mRNA            complement(join(14740..15841,15899..15954))
                     /locus_tag="CBS51388_006384"
                     /product="hypothetical protein"
     gene            complement(14740..15954)
                     /locus_tag="CBS51388_006384"
     CDS             complement(join(14740..15841,15899..15954))
                     /codon_start=1
                     /locus_tag="CBS51388_006384"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_006384-T1"
                     /transl_table=1
                     /translation="MFPAVTGNIDLEALSGICGSISIACWVVVFSPQIIENFRRGSADG
                     LSLLFLIVWLAGDVFNILGAVLQGVLPTMIILAVYYTLADVVLLAQCFYYRGFTLRDEP
                     SSPPRPVSPITAETYDEDTEIPSPVVPRKPTERTALLTSKQRSASYQAPLDTRSPASSA
                     TITPHHQPLLAHRRHSASSFLHTTVDGTHLSPVTPLVEPAKQPRPPRTLTLLQATFFNG
                     SAIILVCAAGILGWYISQTSSLSSDKNNNNKHKDSPDDLKMDTLGQVFGYLCAVLYLGS
                     RLPQILLNYRRKSTDGVSLLFFLFACIGNLTYVLSILAYSPVCERSHHGRCRSDELASL
                     YGRYILVNLSWLIGSFGTLLLDMCIFIQFFLYQDANGGEVDAEAR"
     mRNA            16458..17612
                     /locus_tag="CBS51388_006385"
                     /product="hypothetical protein"
     gene            16458..17612
                     /locus_tag="CBS51388_006385"
     CDS             16458..17612
                     /codon_start=1
                     /locus_tag="CBS51388_006385"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_006385-T1"
                     /transl_table=1
                     /translation="MTAPAIRIPFTGPLPPPIIVPPSARTVAGAIDALLAFLTAPPSPY
                     LRGVDVGRHSQTVLLTGAGISVASGLSDYRGENGTYITNKTYRPIYYHEFVARHEFRKR
                     YWARSFIGWPGLLKAKPNSTHWAIKDIGTKGYISSVVTQNVDSFHSVAHPELPTLELHG
                     YLRSAVCINCRTQVPRDEFQQSLERLNPAWAEFLKKMVDIGALNADNPEEQRRRGLKIN
                     PDGDVDLPEAPYSTFRYPACPTCLEKPPRLQDGSQSRVEVERDGAWLPSSTAGILKPAV
                     IMFGENIDPAVRLGAEEAIDDAGRLLVLGSSLATYSAWRLVERAYKRGMPIGIINIGGV
                     RNESILFSKAEQETEAVCRHVRCSLPSQDILGPVAAQLPSLTHH"
     mRNA            join(17977..18201,18284..18307,18375..19289)
                     /locus_tag="CBS51388_006386"
                     /product="hypothetical protein"
     gene            17977..19289
                     /locus_tag="CBS51388_006386"
     CDS             join(17977..18201,18284..18307,18375..19289)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 171.7;
                     E-value: 3.5e-52)"
                     /gene_kind="regulatory"
                     /locus_tag="CBS51388_006386"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_006386-T1"
                     /sec_met_domain="Pkinase (E-value: 1.2e-76, bitscore:
                     252.5, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MDMDGRDRSKSRTLQPPTADYLDLISNLASPKTFLFHHPRSTSRS
                     HPTPAAQSTTVAPSTTMDKQQPSSFQQLEKLGEGTYATVFKGRNRQTGELVALKEIHLD
                     SEEGTPSTAIREISLMKELKHESIVSLYDVIHTENKLMLVFEYMDKDLKKYMDTRADRG
                     QLDQATIMSFMHQLLKGIAFCHENRVLHRDLKPQNLLINKKGQLKLGDFGLARAFGIPV
                     NTFSNEVVTLWYRAPDVLLGSRTYNTSIDIWSAGCIMAELYTGRPLFPGTTNEDQLIKI
                     FRLMGTPSERSWPGISQLPEYKPNFHVYATQDLSLILPQIDPLGLDLLSRMLQLRPEMR
                     ISAQDALHHPWFRDLPQLQAQLQQQQQQQQQQMAGAYGGMVPPQQTY"
     mRNA            join(20077..20453,20555..20849)
                     /locus_tag="CBS51388_006387"
                     /product="hypothetical protein"
     gene            20077..20849
                     /locus_tag="CBS51388_006387"
     CDS             join(20077..20453,20555..20849)
                     /codon_start=1
                     /locus_tag="CBS51388_006387"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_006387-T1"
                     /transl_table=1
                     /translation="MSTEPNPSAQRPGASPSPPPPAPVPLTPGPRASKLQEIFDKALAR
                     TLRANSYANFSGCFPTPAKHVPASLESVWRQLNAKLEESAKAEFEDILAERDAVRQLNE
                     LDRLVGEAKVRKDRGVGGDSVAPHTLSPEELYKAHLLPHLMETQADLDAKINSVQNQNA
                     ELAEKVQAQRSEIESLLSGLEAVVADLEGAAAATTQFTSEHQLRQEAAQMDGEVKARSE
                     I"
ORIGIN
        1 ccgacccctt gaagaccgat gtggccgagg agttcttcgc ttctgcagta gatgcattgt
       61 tccagcttct ggatgaccca gatggagggc ttccgcatgc ggtgatgcaa ttaagcagtg
      121 ctgttctaca gaaactcgag cgtcaggacg gtcgtgaacg gttccttgag ttcttgttcg
      181 tccagtggtt ctttgcaaag ttcctctata gcgcactgac ctaccctgag gtatgagaag
      241 gctcgcccag atgttttcaa agttcctatt ctaacaccat gtccaggccc acggtctctt
      301 gcttgacttc catatcagaa aagatgctag agagaaactc ctcggacagg tcggactccg
      361 tgcctactcg caagtctttg ctgtccttca ttccatgtcc gttgtccctg catccggcca
      421 ctacatgaag ccttataaac gagccatcgc taatccaaac atgcaggaac cactattcta
      481 tggctcgtcc cacggtgaga aggcacgtgg agagcatgct ttgccggttc gaccacgtcg
      541 acccacgcag gaacgtcagc ggaacccagc cctcttcccg cgcaacagct ctcaacaggc
      601 gggagtcacc tgctgcattc ctgatgctct ccgctgctga tactcttgcc ctgctgaatg
      661 ctcttttccc gaggacaagc gcttctacat gcaattcccc actctcatct tccgggatgc
      721 cttcgtcccc tgctggttct ttggctgctc ggtcagatcg ctctatagcg tctattattg
      781 agccgggatt tttccggcct ccttctgata acatgtccat tcacgccctc caggaccaga
      841 gactatttgc ctctgacatg gccttcctgt cgttaccaga gaattgcatg agccgcaatg
      901 ctgacaggat ccgctttgag ctgtcagacc tgagcgagcc cgatggtcgg acaactctgg
      961 aaccacctgc agctgaagaa tggaccatct tttccatgac ccgaaatgga agatgcttaa
     1021 cctggggtct attccccgat gatggcccat ccagttttcc gggaaacgcc tctgtggatg
     1081 acgttcagtc caccaccttg ggaatggaag acaattctga agctctccaa acggccattg
     1141 tgaaattgat tcaggataac cctgccgatg atgctgccga gtatggtttt atagatcttc
     1201 atggcgcatc ccaagacgct catgtatccc taaagcaaaa gttcgatagg gccatggaac
     1261 attgccacca tgactctgat ttcatcggtg cccactactg gtggaatgcc ggccgacagc
     1321 ttgtccgcag cgttgcaaac tccccatctc gacgcctgga cgactcgtgg attctcgagc
     1381 ccatgcacgc atcgtgtgtc cgctcactcg ctacctcacg ggcggttatc gaacgatgtg
     1441 aaacggatct tgtggccctc aacaggcatg tgcaacgggt gcaaaaatcc gtaaaggaga
     1501 tgatggccac tgtggccaag ctccgagaca agatgtggta catgactgac gtaaagcact
     1561 cgatgaggta cgaagatgcc aaacacgtcg cactagcatt gaagactatg atctactctg
     1621 ctcgcctcta cagacaagca ccaagcgatg gccggtctcg cagcagcatg agaccgttcg
     1681 gaaattctct tctccaaaaa ccagagttgc aagtcatgaa tatcatgaag gcaccgagca
     1741 gtcaaggcgg tcccaacaag ctgtcagatg agcaggtgga cctgatccgc aaatggctgt
     1801 ctcacaacaa catcgacaat ttctgcaaag gtgaggagcg aattcaccgg ttctgctacg
     1861 aggtgaagac aagtatcaat cggctggttg gcgagaccat ggccgaaacc ccggtgctgt
     1921 ggtccagcga attgtatcac aaagagcgag tcatgtacga aggctccagt aaccgaagct
     1981 tcctaagcct ctcctcgagc atgcggcctt tcaatatgtc tagtgaagac acgccacatg
     2041 cctcaccagt gcaggggaat actactcgcc catcagacac ttcaaggttc acgcaggacc
     2101 tacctccgct gaactccaag tcctctttcc agagtctgat gtccgataag tggaaaattc
     2161 ctcgggaacc ctcgatcaca gacgcctctt caatcggcgg gtccccgggg agggctgcct
     2221 caactactac cggcgattcg tacagcactt tctggtcaac gccacatcag cccgcacatt
     2281 atgcaccaag tgcttccagc ctatattccc ggcccccctc tatgttcagc gataacggta
     2341 ttcagccgtc acgtcgcaat gatcgcaaaa cgcacagcaa aggagctttc ttggacggcc
     2401 tgaaacagac cctgacaagc ttgctcctaa gtgacttagg ctccccagtg tggagctgtg
     2461 gaagtgagac ggacgcttgg ttcggaaacg cgctggagca gaagagaatc cggacccaga
     2521 tgaagaaacg cgcgcgcatc caacagttct ataccgagtg tgatgagcga atcgttcatc
     2581 ataccctcca tcgcacaccg tcggaccgtc ggcgaagcag atccctggag tctgcagatc
     2641 gatccacact cggcgatgcc gagacaccgt ctgcatctgc tactgacaat tctatgcagt
     2701 cagacgaaac gcagcgcttc tcgtacgggt ctgtttttcg gcgcctaata gaagtcttct
     2761 cgcgacacgg gaacccattt gtcaagctaa aggcattgcg ggatctgcgg gcgcttgttg
     2821 ttgcatcttt gaactccgat agcgacggta caagcccatt cagtgcaatt gagcagccct
     2881 catacccgcg aggtcgtact cccgggttcc agaacaagag aagcgcccgt catagctttt
     2941 ccgagtctga tgcaaagcgg gctcatgcgc aggattcctc tcatacaccg acgactcctg
     3001 cggccgagtc tgtcattttc gactcccgac cctccgacta ttgtgcaccc accgacaatc
     3061 agatagtgga tgcactacgc agcctcctcc tcgaagtgaa gccgaagacg ctattccgtg
     3121 acttgcagtt catctcagcc tttgttcctt cggagacgtt gaacaagact gacagcggga
     3181 ctgcatttct acagtttggc ttggcggctc tgagcctcaa ggacgagatc tgcaatagca
     3241 tggtcgaaat cgccgataat attgtatctc aagaattcag ccggcgccat ccgcccggct
     3301 acgaccatac accccggccc gggcacgccc tcgaggatgc tgcgggcatg tggataatca
     3361 ctgccaaaga aggcaatcca gttgcccagc gggaactggc cattctctac ctcacccacc
     3421 ctgaactcct cccgcgggtg accctaccac tcactctgtt gcgagacaca ttcaaagctg
     3481 aaatgatgta tcgccgcgac aaggattcca agtccgatcc gcagagcatg tgcctggcac
     3541 tgcactggat gcagctgtcg gccagtggtg gggacgaact tgcacgcaat cgacttcggg
     3601 agcgggagga gttcgagtct cttgcataaa tctccttttc ttttacagtt ctactcatac
     3661 tcggtccttt ccttactttc aattcgtttc tttctttcat tgcttgcgag catgtgcttg
     3721 tgatcatctt taggacttat atctttctct tctttttctt tttctctttt ttccttctca
     3781 catctttcta tgactttgat accaatcacg acctgccgat ttctggcatc cgacgcgggt
     3841 ctacttacgc aactaatttt ggtgcagacg cgcagatcta ttgatatcct gtttgacaga
     3901 tctggatgga cggtgttcac cccggtttcc ccttggctgt tgtattttgc tatgctactc
     3961 ttctgcggga tatccttcgt ctttcacgga gccgggcagg gtcatgagat tcccctatac
     4021 acttatacct cttttttgtg cttggggcgg cattctgcta ttcgatcact tgtttgtcta
     4081 ccattctgtt gctttgcttt ctatcttgct ggtgagtcga cgcatcttta caagggggac
     4141 gaagggaatc gggctcttgg agttctattg catactgggc aaggatggga gtgtagaaac
     4201 gctttgtagt ttgttagcat ctcagaccgc agctggatgg acgcagggaa acccggtcca
     4261 ccagaggggt cagaatacaa gcagctttat gcaacgttga tggggtcagg tagtcaggta
     4321 gcaaccacaa ccacgtagtg ggtcgggagt cgacagtcga tctttcgaca ggtttgagag
     4381 tttgagagtt ggagatggga cagtagggga aacagtagga aacagtccag tccctcggat
     4441 tgcttgcgac gtcatcggcg ggcagcccca cgtgccaggt cactgactgt ctgtttgcat
     4501 ttacttctta ctgcttcttc tccttctgtc acttctgtct caacccaact ggactatttt
     4561 ctggtcgcct tactctctga cccctttttt ttgtacttcc ttcttttccc ctttcttacc
     4621 cctgcttgtt ctggctaagc aaagaaagaa aaaaaaaaga aagtgaaccg agccaccaag
     4681 taatcatcag atccagctgg accgcgcgaa cgtgattcat catccgcaac cgtgccaccg
     4741 ccctcatttg tcgggctcat cgtcagaggc tgaggaatcc cacccccgcc tcatccaggc
     4801 ctccttcctg tgtgtctcgt cgccagctca gcctcagatg ctgcctttcc tttcgggcac
     4861 ttgcagctga ctgtcattga attttccctt tccccctgct cattgaattt ctttcgggtc
     4921 gcatttattg cgcatctgat ccgccttctt atcttgttat cccttccctt tccgcttttc
     4981 ccctcttctt ttttctcata ctttattttc cttctgcggc ggccgctgct gtttacttta
     5041 caaacctcct accttatttc cccccatcta tacatctcga ctacacgact acacgactca
     5101 gtttcggtgc gcttggcgat catgtctcac catatggagg atgcacacaa gcgacccaag
     5161 ggtaaacaaa cctcttgcga tcatccgcat cctacgcctg gttgctaatc ggacagcagg
     5221 tattctgaag aactccagct ctcaggtgcc ccaggtcgcg cagcatgctc acgctacttt
     5281 gacgatccct tcaacctcgg ccgaccctac ggacaccaag gaacttacgc ttcagaacac
     5341 cctccagaat gccggtcgac gtcggtcgtc atccaacact cgccccgggt cttcgtcgcg
     5401 acgacagtct cttgccagca tccacggtca tcacgacgac tcgtcgcccc gcctgaagtg
     5461 ggacgaggcc aacctgtatt tgacggagca ggagaagacg gccaagatga agatcgatga
     5521 gcccaagacc ccctatgcgc cgcgctatga ccccgccgag gatgaggacg agctggcggg
     5581 cgaggaaagt ctgattgatg cgcaggatat agtggtggac gaactggaca agacgaagaa
     5641 ggcgcccaag aagacggtcg cagaggacga tattccggag ttggagctgg gagaggccga
     5701 ggagtatggt ggtgatgcgc atatgggaga tgccgatcgg atcgtgcgcg aacgaagctt
     5761 gagcaatgac tcacatcggg gcgggaagca cgttgtggtc ggggctggcg agctgaacgg
     5821 cgaaaccgag tctggtggag atacgttgat gacggcgggc gaagccgagg aaaagcatcg
     5881 ccagttcgag cagcatcgga agaagcacta tgagatgcgg aacatcaagg atctccttgc
     5941 gtaagttgct cccctattcc caggatggct gtgggatttc tcatggaggt atggtatact
     6001 gacgggcttt gttttccagc caccctgagg atctcgagga cgaaatggac gaagacgaag
     6061 atgaggggga cagctcaagt gccgcggtgc cgcccccgat gcctaggatc ccggagcgat
     6121 ttctaaatgg aggaaagtga gggagcgaaa ggaatggacg gacgggacta agttatcact
     6181 ctactcgaga aggattagga cgagaagagg tgataggaaa ataggatgga gggagggact
     6241 agttgattct tgctgcataa acggactctg tatattcccc agcgttgttt agtcatgatg
     6301 ggacggactt gtatgaatct atgggaagta ctttgctttt tttctttttt tttttttttt
     6361 tcttcttctc tagttgttca ctcttcctgc tagctgatgt ggattgtgtc ggctcttttt
     6421 tttctctcat agcgaatgat gggttgcttg atcgattgat agacgagaga gataaaaatg
     6481 aaatgtacgg ggaggggaga gagttatgga ttattgacac gtcttgttta aaaactagat
     6541 acgatgaagt aaatgagcta gctgtcaggg aaataaccca cccgaagcag ggagagttct
     6601 agactgtttg tctgaccaca gcaggccagg ggggactcgt caccctcggg gttatatgag
     6661 tcgcgtcaaa aaatagaatc atccaatact ctgggaagta ctccgtaaac cgaatcaaac
     6721 caacatagaa gataaaaaaa aaaaaaagaa aaagaaaaaa aaaaaaaaaa aatagggaac
     6781 caatgccatt agagaaggtg ataagtagtc accttgagtc cgcggccaga ctactctgag
     6841 taatagtgag ttagagcacg cgcctctccg ctaagcccga ggctgtcaaa tcatccgacc
     6901 acctgagaca agaagaataa ttatagtatc agaatccaag agtcggcatc tcaaccaacc
     6961 ctcgagtcgg tgccttgcat gtcatctgga ggaagtgagt ggatgtgatc agtcaccgca
     7021 tgctgtaacc tgtcaggggc attctgggat ttttcttggt gagtctgtct gtcggtctct
     7081 ctctctcctg aaacatcctt gcaggcccac tccaagattc aggaggatgg gatggatcat
     7141 tttcggtttc ctagtcgagt tgctattctg agtaacttgg ttagttagtt attctactgt
     7201 actacggagt actagctatg tactctgtgt gtgtgtgtgc cttccttcac ttccactcaa
     7261 tggatcagat gttgaatcaa gtataaggtt tgtgctgggt tctactatta tctagtagtg
     7321 aagagtcatg gtatatgact tttcaaccat gggatggatc catattttaa gttgtttgtt
     7381 tggtctactc tggatctggt ctgaaacctt ccagatgaca gagaaatcga tagataaata
     7441 aaacaaatca gttagttgtc ttgtctgatc gccgttgaaa cctcctaatt gaaattaacg
     7501 gccgctgcag caattaatta attaatccac tgctatctct gattggattg cgcgcgtttt
     7561 ctgtgctttc ttagtttcgt ctttgcctgc ttgtcgcttc gcttcgtttc tttcgcgctt
     7621 tctgtctttt ctggtctctc gtgttttctt ctcttctcct cttcctcttt tctcttcctc
     7681 tctctctctc tctctctctc tctctctctc tttttctccc ctgctgttca tttccacggc
     7741 tgttattgga aagccatccc gctcgcgtcc gatcgcatca cgcaattcca tacattcatt
     7801 ttaattctta tttcccctct ctctatcttt cactaatcta ctgctaccaa ataatacatc
     7861 ccactacatc catcatggcc gatcagcccg aaaagaccgc cgccgctcct gctgcccccg
     7921 aggcgcaacc ccccaccacc gccactacta ctaccgagcc tgcggtttcg gagtctcaga
     7981 ctcaacctga acctcagcca gaagccgaac aaaaagtcga gcaggcgacg acaggagaag
     8041 aagcatctcc tgcccccgct gccacggaac ctcccgtgac ggaacccact cccgctcccg
     8101 cccaggaggc ccccgaggat aagaaggagg aagcacccaa ggaagagacc aaggagacca
     8161 aggctgagga atccaaggag gagcagaagg ccgaagagcc cgcggctgag cccaaggccg
     8221 aagcagcaaa ggaggaggaa caaaagcccg ctcagcccga gtatctggcc aagaacccgg
     8281 ccctgagcca gttcttcgat cgtctgtctg ccattctctc ctccactggc cacaatgaga
     8341 tgtggggtgt caccctcaag gactcctcgg atgtccccac cgtcaacatt ctcatcaagt
     8401 tcctgcgcgc caacgagggt aatgtcaagc tggccgagga gcagctgact aaggccctgc
     8461 aatggcgcaa ggagatgaac cccctcgccc tgaccgaggg ccgctacagt gctgagcgct
     8521 atggtggtct gggctatgtc accaagtatc ccgaggcgaa tggcaaggag accattgtta
     8581 cttggaacgt ctacggtaat gtcaagtcta ttgatcagac ctttggcgat gtagatgggt
     8641 aagtgctgct gttgctgcta tttcggaatt gtgaagaggg ttaaatctaa ctgtcgccta
     8701 ggttcatcaa gtggcgtgtc gcgctcatgg agctcgctgt caaggacttg aagttgagtg
     8761 aggcgacgac cgtgatcgac tacgacggtg aggacccgta ccagatgctc caggtccatg
     8821 actaccagaa cgtcagcttc ctccggctga accccaccat caaggcggcc agcaagaaga
     8881 ccatcgaggt gttctccatg gcctaccccg agctgctgcg ggagaagttc ttcgtcaacg
     8941 tgcctgccat catgggctgg atgttcgccg ccatgaaggt cttcctcagc aagaacacca
     9001 cccgcaagtt ccaccccatc tccaacggtg ccaacctggc ccgcgagttc ccttccctga
     9061 aggacaagtt ccccaagacc tatggtggta acggcgcgac cctggaggag gatgcgttca
     9121 cggtcaacct cgagaaggcc gagcctgccc cggaggctcc caaggaggag cctaaggagg
     9181 agtccaagca ggagcaggcc gaggctccca aggaagaagc caaggcagag caggctgagg
     9241 ctcccaagga agaggtaaag gaggaggcca aggaggaagc caagacagag cagccggcgg
     9301 ccgaggagcc ggccaaggca gaggctgcag tgacgaccca ggaggcgccc gccgcagcgg
     9361 aagccaaata aaaagctagc aagaggcgta attcacacct ggtcggaatg aggccaggat
     9421 cacataattt acggtaatgg atgggacagg ttggattgat acccggggga atcggtagaa
     9481 tgattccgtg tcgttttgcg tacttgatac ctctcgatag tgtgtgcttt atatgttctg
     9541 ggattgatga tagagtgcag aaacactaga tagtaatatt taatgtaaca ggtcatatag
     9601 ccgctgattt aacgttacga tctttctctc gcgtcgaccg ttattccatg cgttcctgca
     9661 tgcagcagta aactataaca ctggatttcc tgctctcttt atgctgatct ccagccaggc
     9721 acccctgatg actcagcagc cagtgtccct cagtttcctg caccaacaaa aacaccaact
     9781 gcacagctgc tgcacgaaca acaggcagca aataaaatcc gggcaaggga gattagtgtg
     9841 ttgttcttcc tttctctcct ctcgagtgtg gttgtatcct ataagctatc cctcccacta
     9901 tccctctctc cactaatctc aaccctgcca ttccaccctt tcaattcccc cccccccccc
     9961 cccccccaat accataagtg tacaacaacc ccccatcaca atgtcgggat ctcacatcgg
    10021 cccgtggaga actcccgccc aaggccatct cacccccgac gccaacggcg atctcaaaac
    10081 tgactatacg cgctggcgcc tccgcgacga ccgcggccgc caaacctggc actacctgga
    10141 atccgacgca gagaacgagc aatggcctca atccatcgca gataagtact tcttgggtct
    10201 ccccacggga cttcccgagc tccccaaacc ccagacgcct ctgcaatgcg ccgagaacgg
    10261 gctggagttc ttctccaagt tgcagctgga gccgggaaat tgggcgtgcg agtatggcgg
    10321 gcccatgttc ttgctgcctg tcttgattat cacgtactat gttactaaga cgcctattcc
    10381 gccggagtat gccaccgaga ttaagcggta tttgtttgct aggcagcatc ctgaggatgg
    10441 cggctggggg ttgcatattg aagctcacag ttctgtgttt ggtacttgta tgaattatgt
    10501 tacgttgagg ttaatcggtg tgagcgagga tgatcctagg atgatcaagg ccagggggtt
    10561 gttgcatcaa tttggaggtg ccatctatgg gccccattgg gcgaaattct cgctggctgt
    10621 cttgggtgtg atggattggg agtgtgtgaa tccggtgccg ccggagattt ggtacgtttg
    10681 tttctatcat gtctagtggg tgatttgtgg atgggatact gattcgacca ggctacttcc
    10741 tgactgggtg ccgtttgcgc cctggcgctg gtggattcat attcgccagg tctttctgcc
    10801 catgtcgtat ctgtggtcta agaggttctc gcatcccttg gaccctctca ccaagcagct
    10861 gcggcaggag ctgtataccc agccgtatga ctcgattgac tttgcggcgc atcgcaactc
    10921 aattcacaag gcagacaatt actaccccaa gacttggctg ctgaatacct tgaactctct
    10981 gctcgtcaac atctggaacc cctaccttcg tgtccctgcc attgtgcgtc gcgcggagga
    11041 gtggacgtgg gagttggtcc gcatggagga cgagaatacc gactacgctg gcctggggcc
    11101 tgtgagcaac ccgttcaaca tgattgtgtg ctacgaacat gacggtccgg acagctactc
    11161 ggtccgtcgc catcgcgaac ggctgcacga ctacatgtgg atgaaggacg agggcatgct
    11221 gatgaacggc accaacggcg tccaggtatg ggatacggcc tttatcacgc agagtatcgt
    11281 ggtggccggg ttcggcgatg acccgaaatg gcggcccatg ctcaccaagg cactggagtt
    11341 cctggaagac catcagctgc gcgagaacgt gccggaccag gagaagtgct accgccagca
    11401 ccgcaagggc gcatggccat tcagcaacaa gacgcaggga tacacggtca gcgactgcac
    11461 cgccgaggga ctgcgctcga ccatccagct gcaggagatg cacaacttcc cgaaactgat
    11521 ctcggaggag cgattgaagg acagcgtcga ctgcctgctc ctgatgcaga accccactgg
    11581 tgggttcacc gagtacgaaa ccacgcgggc atccgagaaa gtcgagtggc tcaacgcagc
    11641 cgaggtgttc ggcgggatca tgatcggata cgactatccc gagtgcacga ccgcgtccgt
    11701 caccgcgctc tccctcttca gcaaatacta tccgaattac cgggctgcag agatcaagtc
    11761 cgccaaggaa aaggccgttc agtacatcaa gcgggtgcag cgcgccgatg gcagctggta
    11821 cgggtcctgg ggcatctgct tcacgtacgc ggcgatgttt gccctggaga gtctggccag
    11881 catcggagag acgtacgaaa cgagcgcgga ctcccgacgc ggatgcgagt tcctcatctc
    11941 gaagcaaaag gaggacggcg gctggggcga gtcgtacctc agcagcgaga agcacgtcta
    12001 tgtgcagcac gagaagtcgc aggtcgtgca gacggcatgg gccagtctgg cattgatgga
    12061 ggccgggtat ccgcataagg agccgctgcg gaaagcaatg cagctgctga tgtcgcggca
    12121 gcaggccaat ggagagtggt tgcaggagtc gattgaggga gtgtttaacc aatcttggtg
    12181 agtatcatga tcgattgatt gagagttctc cactaacgag tgacagcatg atttcgtatc
    12241 ccaactataa gctgtactgg ccgatccggg ccttgggatt gtatgcgcgc aagtttggca
    12301 atgaggagtt ggtctgatct tctatggatt gttcttctat gagtacatgt attactacta
    12361 tactactata accttctact aattgataat atgattcatg tatactatct tctttatcgt
    12421 tgatctggag agtatagatg tgtagccaat cacgtggatg ctccgctccc cgcatctctc
    12481 caaagaagat catcgaactt gtttccattc cattcacctc tccacttgta ttcctctttc
    12541 tctttcacgt tatttccttt tctcttcgga gattccctta caaacaacaa gactcatttt
    12601 tcacatctcg tactcagacc catacttaaa ccctatctac ccacccaaca aacacaacac
    12661 aacacagcac aacgcaacac ctccatccaa acaccaccac actccaaccc accacctcaa
    12721 aacctcaaaa tgaacgccgc ctccctcggc gacaccgccc tccaacagtc cgacccccac
    12781 accgcaacaa ttcactacac gaccgccctc ctcacgcacc cccgctcgcc cagctacttc
    12841 atcaaacgct caacagcctt ctcacgccta aagcccacac cgaacctctc cgccgccctc
    12901 cgcgatgccg aatccgccgt tcttctcgcc cgcgagcggg ggaaacgcga gctgatcgtc
    12961 gaggcgcaga tgcggagagc catcgttttg tttctcatgg ggagatacgt tgctgcggag
    13021 ggggtggtag gcgtggtgga gggtatgatt ggattggata aggacggtaa tggtggggaa
    13081 gataaggagg agaaggtgag gaaggcgatg gggggtggtg ctgggaaggg tattgaggcg
    13141 gaggtgagga tttggggggc gaagattagg gcgaaggtca acggtttggg cgagcagagt
    13201 ggtgagcgtg gggagaaggt ggaggaggtt ccggtggggg ttaaagtgcc gggggagaag
    13261 gagttgaggg gacagttgga ggagttgagg ggagggaagg ttggtgaggg tattggtggt
    13321 gaagagaagc agagtcagaa ggttgaggat aaggtggagg agaaggagag agctgaggtc
    13381 aaggagactc agcagcagca gcaacaacag cagcagcagg tcaaggtccg tcatgaatgg
    13441 taccagtccg gtgagacggt tgttgtgacg ctctacgtga aaggcgtgcc caaggataaa
    13501 gtggctattg agctgaaaga ggactcggta tgtattcatt ccccttgacc taaacatgca
    13561 agccactaac ctatatacat agacatccat ccaattcccc ctcccctccg gcgccgaata
    13621 cgacttcact ctcgacccgc tcttcgctcc catcgacccc tccacctcta aagtctccgt
    13681 cttctccaca aagatcgaaa tctccctgcg caagaaaact cccggccaga aatggagcgc
    13741 cctggaatct accaccggac ctgtcatctc tactccccag cccacggtta cacccaccac
    13801 taccaccaca caagcccaag ccccatcata ccccacctcc tcccgccacg gcgccaaaga
    13861 ctgggacaag ctcgcctcca gcctaaccca gaaatcgaaa aaggacaaga ccaagagcag
    13921 ctcaaagccc aaggatgaac aaggagaagg agaagaagat gatggagaag catccgacgc
    13981 cgaatccatc aactccgact tcggaggcgg tgatgccgtc gatggcttct tcaagaaact
    14041 ctatgccaat gcggacccgg atacccgccg cgctatggtg aagagttatg tggagagtca
    14101 ggggacgtcg ctgagtacga attgggatga ggttgggcag gggccggtta aggttaggcc
    14161 gcctagtgag tgattttctt tcttcttttc tttctcagtt tctgagagaa aggaaagagg
    14221 ggagcaagaa agaattgttg gttgaaagat ggagaagaag gggatatgcg aattgcaagc
    14281 gtggagttat ggtctacatc catgttgtgg gtgcatgtgg gtggtgtttt aggttctgaa
    14341 gttgcttccc ttgctagtta cttgttttgt gtagcttagc ttagctctgc tttacttgtg
    14401 taatggtaat cattgcaaga tgtcgagact ctgctattac ttaccttata aacatgatac
    14461 gtagactact acatgataca cgtgatgtag aagcaagtat agtataagat aataaataat
    14521 tatatacacg aaaagcaact ccgatccaat caaacgccaa tcacatgagc aagagtagca
    14581 tagcaacctg gccatatagc acgcaagcgt tttcagaata aatcattata aatcaagcaa
    14641 tccctaagta ccaaccccaa cacctcttta tgtcttccca gaggcatagt caagaaaaga
    14701 gaataaacaa gagagaaatg taaaccacat gcgaatattt tacctcgcct ctgcatccac
    14761 ctcaccccca ttcgcatcct ggtacaagaa aaattgaata aagatacaca tatccagcaa
    14821 taacgtgcca aagctcccaa tcagccaaga cagattgacc aggatatatc gaccatacag
    14881 cgatgccagt tcatcagatc gacaccgacc atgatgcgag cgttcacaca caggcgaata
    14941 cgccaagatg gaaaggacgt aggtcaaatt gccgatacag gcgaagagga agaagagcag
    15001 ggaaacaccg tctgttgact tgcggcgata attgaggagg atctgtggga ggcgggaacc
    15061 gaggtacagg actgcgcaga ggtagccgaa aacttggcct agtgtgtcca ttttcaggtc
    15121 atcagggctg tctttatgct tgttgttgtt attcttgtcc gatgagagtg atgacgtttg
    15181 gctgatgtac cagcccagga tgccggcggc acagacgagg atgatggccg aaccgttgaa
    15241 gaaggtggct tggagcagtg ttagggttcg agggggacgg ggttgcttgg ctggttcgac
    15301 gagtggagtc actggggaga ggtgagttcc gtcgacggtc gtatgaagaa atgaagaggc
    15361 ggagtgacgg cgatgggcga gcaagggctg gtggtgagga gtgatggtag ccgatgatgc
    15421 tgggctacga gtgtccaaag gagcctggta agaggcactg cgttgtttgg aggtaagcaa
    15481 cgcggtgcgc tctgtgggct tccgaggcac gacaggggag ggaatctcag tgtcctcgtc
    15541 gtaagtttct gctgtgatgg gagagacagg ccgcggcggc gaggatggtt cgtcgcgcag
    15601 tgtgaatccc cgatagtaga agcattgtgc taagagcacc acatcggcta aagtgtagta
    15661 caccgcgaga attatcatgg ttggcaggac gccctgcagg acggcaccga ggatgttgaa
    15721 cacatcgccg gcaagccaga cgatgaggaa aagaagcgaa aggccatcag ctgagccgcg
    15781 acgaaaattt tcaatgatct gtggggagaa gaccaccacc cagcacgcaa tcgagatgga
    15841 tctatcagtg atcagtattg aacatgtcca attctagcat actctggcat aaacataccc
    15901 acatatgcca ctcagtgcct ctagatctat attgccggtg actgcgggaa acatgtccgg
    15961 gcggtgcgaa cgagagagcg attgggcgtt ttcccaatca atgctctact ctataatcta
    16021 aacaggaaga ggctagcaaa accggtcgac agcaaacaaa gacgcgttga tggaatgaag
    16081 cagatggccg gcgatgacgt tcgcagagtc tgcgaagggt gcagatcacg tgggacgatc
    16141 cggggtagct cctctcagtc tagaccaaga atggacaccc agatcgactt gcttccactt
    16201 ttacttcttt tggctgggga cgctttgttc cttgtcggcc gcaatgctct gtatcgtaca
    16261 ttctgggcct tctggtcatc tattactatc tgatcaagta atacttggcc ccgtgtagtc
    16321 tgaccatcca tttcacactc aatgggactg tgtacatcat gtgaccgatt agtcaagccg
    16381 tgacgtcgat gatcaaccag cgcccatctg aacccagcct tctcgaagct tcaacatcca
    16441 tcaatcatgt ggcttcaatg actgctccag caattcggat tccctttacg ggccctctgc
    16501 ctccgccgat tattgtccct ccgtccgctc gcacggtcgc aggtgccatt gatgcgcttt
    16561 tagccttttt gacggcccca ccgtcgccgt acctgcgcgg cgttgatgta ggcaggcatt
    16621 cccagacagt gctcttgaca ggcgctggta tctcggtagc ttcaggcctg tccgattatc
    16681 ggggtgagaa tggcacgtac atcacaaata agacgtatcg gccgatctac taccacgagt
    16741 tcgtcgctcg ccatgagttc cgcaagcgat actgggcgcg aagcttcatt gggtggccgg
    16801 ggctcctaaa ggcaaagcca aattcgacgc actgggctat caaagacatt ggtacgaaag
    16861 gctatattag ttcagtggtg acgcaaaatg tcgactcctt ccattctgtc gcgcatccag
    16921 aactacccac actcgaactc cacggctact tgcgttctgc cgtctgcatc aattgtcgaa
    16981 ctcaagtccc gcgagacgag ttccagcaat cgctcgagcg gctgaacccc gcctgggcag
    17041 agttcctcaa gaaaatggtc gatattggcg cgctgaacgc agacaaccct gaggagcaga
    17101 gacggagggg cttgaaaatc aacccggatg gcgatgtaga tttaccggag gccccttatt
    17161 cgacctttcg gtatccagca tgtccgacgt gcttggagaa gccaccccga ttgcaggatg
    17221 ggtcccaatc ccgtgtggag gtagagcgcg atggggcttg gcttccaagt tctacggcgg
    17281 gaattctgaa gccggcggtc attatgtttg gagagaatat cgacccagct gtcaggctgg
    17341 gtgcagaaga ggccatcgat gatgcgggca ggctccttgt cctgggcagc agtctcgcca
    17401 catactcggc gtggcgccta gtggaaaggg cctataaacg agggatgccg attggcatca
    17461 tcaacatagg aggtgtccgg aacgagtcga tcctctttag caaggcggaa caagagacgg
    17521 aggctgtatg ccggcatgtc cgttgcagtc tcccgtccca ggatattcta ggccctgtgg
    17581 cagcacaact gccttcactt actcatcatt agggtccatg tatagattga aaaaaggatg
    17641 tgatgtatag atggcggtga ggtgtatgaa ccgcttacag ataagcatca tagtatatgt
    17701 acaagcgata aaagttgaat ccaagcttgc attattggag acgttactat tttcaaagta
    17761 actgtatcca tcagatggaa tactctagaa aagataatta taggcactcc agaatgattg
    17821 gcaacggcga gctaagatag gcatgtaata gacgccggga tagtggagac cagcaaagta
    17881 ggagaaggcg agttacaaag tgatggcggg ccagtcagcc gcccgtccgc tgttcgattc
    17941 cagcgcgggg ctctgcattc gccggttcag atcagcatgg acatggacgg tcgcgaccgc
    18001 tcaaaaagca ggacattgca acctccaacc gccgattatc tggatctcat ctctaacttg
    18061 gcctctccca agacttttct ctttcatcac ccacgctcca cctctcgttc tcatccaact
    18121 cctgctgcgc agagtaccac cgtcgcacca tcgaccacca tggacaagca gcagcccagc
    18181 tcgttccagc agctggaaaa ggtgtgtttt gatggcttcc ctactgtcta ccaagatatc
    18241 acccatcaaa tgagagattt gtgatgctaa ctgctgattc tagcttggag aaggcaccta
    18301 tgccaccgta cgaacccctc cctccgcacg gccgatcctc ttaaatcgca ctatgtactg
    18361 acaccctctc gcaggtcttc aagggacgca atcgccagac tggcgagctg gtcgccctga
    18421 aagagatcca tctcgattct gaagagggaa cgccatctac cgccattcga gaaatatcgt
    18481 tgatgaagga gctgaagcac gagagcatcg tgtcgctcta tgatgtgatt cacacggaga
    18541 acaaactcat gctcgtcttt gagtacatgg acaaggatct gaagaagtac atggataccc
    18601 gcgccgaccg cggccagttg gaccaagcca caatcatgtc attcatgcac cagcttctca
    18661 agggcattgc gttttgccat gagaaccgcg tcctccaccg cgatctgaag cctcaaaacc
    18721 tcctcatcaa caagaaggga caacttaaac ttggagattt cggtctagcc cgcgcctttg
    18781 gcattcccgt caatactttc tccaacgaag tcgtgacctt gtggtaccgt gccccagatg
    18841 tgcttctggg cagccgcaca tacaacacga gcatcgacat ctggtctgct ggatgtatca
    18901 tggcggaact ctacactggc cgtcctctgt tccctggcac caccaacgaa gaccagctta
    18961 tcaagatctt ccgcctgatg ggaacccctt cggaacgctc atggcccggc atctcccagc
    19021 tcccggagta caagccaaac ttccacgtat atgcgacgca ggatctcagt ctcattctcc
    19081 cccagattga ccccctaggt ctggatctct tgagccggat gctccagctc cggccagaga
    19141 tgcggatcag tgcccaggac gccctgcatc acccctggtt ccgcgatctc ccgcaattgc
    19201 aggcccaatt gcagcaacag cagcagcagc aacaacaaca aatggctggg gcgtatggtg
    19261 gcatggttcc cccacagcaa acatattgag ttcttccttt gatgcgtttc tgttttcctt
    19321 atagttcgtt ttcatcatgt acagcctatc gtttaccttg acttgcgttc atctgcttcc
    19381 tcgtggaagg cttgacgagc aacggattcg gttttagaat ggggagcgcg gcgtttgact
    19441 cctgagagga cattcgaatg attcttgctg ttttctgctt tctttgcgtt gcatatggac
    19501 ccagagaacc gatggcatct cgtagataaa cttggccatt atacttatct attgctctct
    19561 attaccttcc attatcgtag cttattacaa gcgcaggggc agcagcgacg atatcttgtc
    19621 ccgcagacaa ctaaatcaat cctgacaagc ctttatcagt gccggatata agccctaaca
    19681 ttccacgcaa ccaagttgaa cacagtagct aatctcggct cgccacgaaa agacaactta
    19741 caataaggac catccttata tttttcaaac tgatttaaac actacaaata tacagtagcc
    19801 tacacatctt actttatagg tacctaaact ctgtaatata tgtaggtact ccggtcttct
    19861 ggcgggatct atatctatca cgtgattaat agtcgcgcgc gtcttccggc gcgtcctcca
    19921 atcccatcat caatctacta ttctccataa tcctacaacc acgaacaaca acaacacaaa
    19981 ggagcttgaa acgaacttaa ggctcagcat aacaaatcac tgcaccccaa tcgaaactct
    20041 tcaaccacct caaaccctca accggcgaaa gtaaacatgt ccaccgaacc caacccatca
    20101 gcccaaagac caggcgcctc cccctcacca cctcctcccg cgccggtccc cctaacacca
    20161 ggcccgcgcg cctccaaact acaagagatt ttcgacaagg cgctcgcgcg cacgctgcgc
    20221 gcgaactcgt atgcgaattt cagcgggtgt tttccgacgc cggcgaaaca tgtcccggct
    20281 agcttggaga gcgtgtggag acagttgaat gcgaagttgg aggagagcgc gaaggccgag
    20341 ttcgaggata ttctggccga gagggatgct gttaggcagt taaatgagtt ggaccggttg
    20401 gttggggagg cgaaggttag gaaggataga ggagtcggtg gggatagtgt tgcgtatgtc
    20461 tccccttcct tattcctttt tttgctattt ggcatcatta cattgggggc ctgtggatga
    20521 tggatggcta actggaatga tttgtgcttg gtaggccgca tacgttaagt ccggaggaat
    20581 tgtacaaagc gcatctgttg ccgcatctga tggagacgca ggcggatttg gatgcgaaga
    20641 ttaattcggt gcagaatcag aatgcggagt tggctgagaa ggtccaggcg cagaggtctg
    20701 agattgaaag tttgttgtcg gggttggagg ctgtggttgc tgatttggag ggtgctgcag
    20761 ccgcgacgac gcagtttacg agtgagcatc agcttcgaca ggaagctgcg cagatggatg
    20821 gagaggttaa ggctagatct gagatctgat ctggtggctt gggattttta cgatggcggg
    20881 gacagccccc ctccctttca acgttcgaat ggatcggggt atagtatgac tacgacaaca
    20941 aaacctccat atcaccggga cccatccatc cgtcttcgac cacatcctcc gcaacgagca
    21001 tcagctcttt gggcgcagct ttccggagct gctggagttt gtccttttgg cctgccagtg
    21061 cagcagcaat ggcctccttg caggttccat ctcgttcctc gtccgcagca ccgtctctct
    21121 tcgccaaggc tgctgcacca cggtaataag tctgggcgtt gcgcagcagt gtagctgcgt
    21181 tatctcgggc catgttatag tcccacggag ccaagccaag cctccaccta cccatctcca
    21241 cgtctcctct ggccagatga atctttggca ggttttcagc attggggagt ttggacgctt
    21301 tgctcaatgc gtccaaggca gcggacaggg attgccatcg aagggacagc gctttcataa
    21361 aggcctccgg ctcatacgga gggagatctg tgagcgccgt attgaaagaa gtgagcgcat
    21421 ctgctttgct gcacaggcca tctgggtcgt tggatagatc cagatcagga ccgaaagctc
    21481 gcgaaacttc ctcggagtat gttccaactt cggtccgtcc gcttctgtac aggacttcat
    21541 tcagggagca ggcgaacttg gcacgagcca gattggcctc gtagtgcctg tttgacccct
    21601 cgacatatgc cgagattcgt ttctgcagct gctctgatga atactcttct acccaagtga
    21661 caccttcttc agggttgaac gtgagtaggt tacagaggct tgtgatggct tccagttgtg
    21721 cgacagctgt gtcgacgagt gtgtccttag tcacgggctc aacaatagca gcccattgtt
    21781 cttgctggtc tgacgacttc gactcgtccg caggtggcag ttctggcggt gtatcttgca
    21841 tctgagtttc agcagggtcc atttcgccgg acgtcatctg gttgatctgc tcctgcattt
    21901 cggtgtactt gagttcttgt acagttaggc aacgttggaa gagttctatg gcttcttgca
    21961 aaagctttac tgcctgagag agccggtcat ccgatgggcg tttggattca gtcaacgcct
    22021 cggcaatgct ggtgagtact tgggctgtgt tgaaaagcgc atctgcattg tcttgctcca
    22081 ggtcaagcgc tgctctgtga gaatcaagcg ctactcgcag gacgtccaat agtggcgcag
    22141 acagctgagc agctagtttg ggatgttgcg tgatttcata ttgaactctc gctctatcag
    22201 atgtcagtaa ctaaggttac tgacggacgc gtccataacg agtagataag gcaacgatga
    22261 atttggatga cgtgtgacgt acttgttata tgccaggtca aacgcactgg gatgttt
//
