LOCUS       An15                   41500 bp    DNA     linear   PLN 01-NOV-2020
DEFINITION  Aspergillus niger strain CBS513.88.
ACCESSION   An15
VERSION     An15
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Circumdati.
COMMENT     'Annotated using 1.7.4'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-03 02:41:14
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1181097
            Orig. end    :: 1222597
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..41500
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[1197634:1197686](+),
                     [1197741:1198588](+), [1198653:1205182](+)}"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(16538..16589,16645..17491,17557..24085)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..41500
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..41500
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T1PKS"
                     /region_number="3"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     mRNA            join(1..224,284..1022)
                     /locus_tag="CBS51388_009551"
                     /product="hypothetical protein"
     gene            1..1022
                     /locus_tag="CBS51388_009551"
     CDS             join(1..224,284..1022)
                     /codon_start=1
                     /locus_tag="CBS51388_009551"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009551-T1"
                     /transl_table=1
                     /translation="MKLSTFLFSLLATSQVTLATPIPIVDVAELPSDTGLEIRSPNPAD
                     ELLAILEQRDTRVCEILNRTIRSIGTSKFTVVYIVMGSRLARQVCEYAGGSRCEEISYI
                     ISDGLLLAYVAAAHYSGAIPEGLPGKRDVDVSQDYFQLWETMLSSSGDISYDYLTPLSN
                     TSNTLPLVRRQDQPLPIHRIQITGFAHNNSPKHDIIANHYENGDTVLQLPLAGGVPGAN
                     DTEGLDLRKRFDNPGFKIAFTTRGRSQLTQAHQKSMALAGAATWAVYADNANHKMDDFI
                     GFAETDHAANFYYRIIPELRGFGTNYETVDICGGMASYL"
     mRNA            2104..3237
                     /locus_tag="CBS51388_009552"
                     /product="hypothetical protein"
     gene            2104..3237
                     /locus_tag="CBS51388_009552"
     CDS             2104..3237
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 114.2; E-value: 1.2e-34)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CBS51388_009552"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009552-T1"
                     /transl_table=1
                     /translation="MTTINGHCDPAFTGVRDLLQQLINNEEELGASICVNIDGQNVVDL
                     WGGHADPARTKPWEKDTLTVVWSVSKVITAIATNILIDRGLLDPNEKVSKYWPEFAANG
                     KENILVSQILSHTSGVSSWELPNTLDDIYDAKRGADKLARQAPWWTPGEHSGYHVTNQG
                     HLLGELVHRVTGKPLDEFIRDELASPLAADFQLGVPEKDWPRTADVSPPPPLSLDGVDP
                     QSVMFKSFASLPIPAEESMSPGFRKALIGATNGFSNARGIARIASVISLGGTVDGKQYL
                     SPETIDRMLEEQISGPDLVLMYHLRWGLGVGLPVPETFPWLPDGRIAFWTGWGGSVVVM
                     DLEKRMTIAYVMNKMGQGTLGSDRTAAYVRAVYDCLA"
     tRNA            complement(3501..3574)
                     /locus_tag="CBS51388_009553"
                     /product="tRNA-Val"
     gene            complement(3501..3574)
                     /locus_tag="CBS51388_009553"
     mRNA            join(4433..5429,5492..6111)
                     /locus_tag="CBS51388_009554"
                     /product="hypothetical protein"
     gene            4433..6111
                     /locus_tag="CBS51388_009554"
     CDS             join(4433..5429,5492..6111)
                     /codon_start=1
                     /locus_tag="CBS51388_009554"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009554-T1"
                     /transl_table=1
                     /translation="MSGNDVPSYDEFAVGWICALPLEMTAAKAVLDEEYPSLHLPKQHH
                     NTYVLGRISGHKVVITCLPFGIYGTTSATAVVEQMLFTFRSIRFGLMVGIGGGVPSAVD
                     VRLGDVVVSKPTAGLPGVIQYDYGKTVASGRFEQTGTLNKPPIVLLSALSSLEADRLAG
                     GSDIGTYEKIIADSLRAAKDPSVFRYPGAEHDWLFDASYDHDPRFASCAECDPERRVRR
                     KPRRSCTPVVHYGNIASGNQVMKHGLTRDRIAQTTQGILCFEMEAAGIMDYLPCLVIRG
                     ICDYSDSHKKKEWQGFAALTAAAYAKLLLSKIPVHRSEASTLIQAPGSKNSSDSFDVRF
                     DTIEMPQAAISVGREAELAMITKSLLSDRFRGIVTLYGMGGIGKTELSIMYIMRHRQKY
                     SSVFWIDGSSLDKLYSSYTQAAMRIIHDHPGDQSLRKALKEGDQIQLVGSVNEWLSRPS
                     NNRWLLIYDGFDLPMVEGFDKAEIMKMRLPPSKQGHIIITMRSYDIGIGDQIQVRKLAA
                     IDDGLDLLTHVCGRPNLRDGK"
     mRNA            complement(7690..9354)
                     /locus_tag="CBS51388_009555"
                     /product="hypothetical protein"
     gene            complement(7690..9354)
                     /locus_tag="CBS51388_009555"
     CDS             complement(7690..9354)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 270.3; E-value:
                     3.8e-82)"
                     /gene_kind="transport"
                     /locus_tag="CBS51388_009555"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009555-T1"
                     /transl_table=1
                     /translation="MEAAAHSLPSSQESDFAVNNHLPHREESDEKGHDADASATDDDVR
                     KITGFRWFLICAALYLSALMYGLDTTIAADVQGAVIERFGDVSQLAWIGAGFPLGSVAV
                     ILPYGFLYTVMNMKWLYIAGIVLFQGGSALCGGAPNMNALIVGRVIAGAGGTGIYLGGL
                     NHFSAMTTRNERGTYLTGTGFVWGVGAILGPVVGGGFSDSSATWRWGFYLNLVIGAITA
                     PVYLFYLPAIHPGAGQSLRKRLTRLDYLGFVLSAAMWVTFALGFISAGGIWAWDSGATI
                     ALIVLFGVLFILYALQQYLCIFTTPQTRSFPGHLLRSRTQILLYITTTCANTAMFFTTF
                     YIPIYFQFTRNDSSLMAAVRLLPYLLVTITINLAIGWLLPKAKYYMPLCLISGILLTLA
                     SALFVGYLSPSTPAGQIYGFTILMAVGTGMTMQLGYAVASLKVPPEDIFSAINLQNVAQ
                     IGATVICLVVASQVFQSTAVKNLKGVLDGRGYSEAEIRNAVAGVQSTLLKSLSGELRDR
                     AIKAITDAMARAFIIPLVAGAVGVVSSLGMRRERLFG"
     mRNA            complement(join(10184..10861,10925..11953))
                     /locus_tag="CBS51388_009556"
                     /product="hypothetical protein"
     gene            complement(10184..11953)
                     /locus_tag="CBS51388_009556"
     CDS             complement(join(10184..10861,10925..11953))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 125; E-value: 6.4e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CBS51388_009556"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009556-T1"
                     /sec_met_domain="p450 (E-value: 2.9e-32, bitscore: 107.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MAPSYIASFVELFHGYPAVFSITICLVGLYVLYRWLLPSPLPGIP
                     YNKQAATSILGDVPALRGDPAGLAKWCSKQLEEHGSPICQALMGPLSKPVVLVADVGQT
                     RELLMGRSDFDRSSYIIDRFPLFGEFHLNMKTGDSWRTSRSWLKDLLAPHYLHQTVGPI
                     IHSSVLNLIHLWESKARVANGRPFSMLADLKTLALDVIVRFHFGQDFQDSALRRQIEFV
                     EQLDNSQLGVGKHTDVIFPQASLHPFQQGLTDVGDRMAAIYTTKWPPSIVSWWARYMSP
                     YYRKFFVGKDRFIRKHINLALQRFGNDEEAKTGIDYMVYREQKSSRKADRQPMYGKQIM
                     IDEAYGNLIAGQHTTSAALVWILKLLAEHPAVQTRLRDELQTVCAAAVQEGRLPTAAEI
                     IQFRLPYLDAVLEETLRLRAAMLVPRDATRDTELLGRRIPKGTVVLLVCQGPDYSSSPS
                     SLYWSDVKTTRKYPGGGNPDLEAFDPERWLVQNERGELEFDGSSYPQLAFGLGIRACWG
                     RRLAQLEMRIMTVMMTWKFDFLDVPEALAGHEATYDISYRAKKGYLRLRSR"
     mRNA            complement(join(12686..13709,13768..14241,14301..14449,
                     14515..14796,14871..14936))
                     /locus_tag="CBS51388_009557"
                     /product="hypothetical protein"
     gene            complement(12686..14936)
                     /locus_tag="CBS51388_009557"
     CDS             complement(join(12686..13709,13768..14241,14301..14449,
                     14515..14796,14871..14936))
                     /codon_start=1
                     /locus_tag="CBS51388_009557"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009557-T1"
                     /transl_table=1
                     /translation="MHPTGRKRRVTTCVPCYTRKQRCNRQYPCNHCTRRRRPEECVYQS
                     IITGDPSNTFLLEPARDPEPQEPPNVQLPNGSSKASPAEAQNSASNSHSALAKSFGYFE
                     HSDSNTMALLKKWDLDSEGDTDQSTQGLSTAVLETVKQVLEKIPPRPILDFLMQYFVDE
                     LNWMKQIIHPPSFLTQYQHWWTKEWPLSVDDIEFAALVLRIGAYSAQFLPSPTHTLDRI
                     RGQSLSDIRDTCSHLGGELARACLSLNWKGSLVRVQHILFAAFRSSCEGRTDKFWEGIA
                     SACSAAQKAGIHTVAPVPGEDSSQVLEKEMRRRTLCGLYVLDSHLARQLDRVPFLPDNL
                     VLETLPRLRLAPFIGDLAASADAPEDFTERLMQVRLGRFWRSFGSRRNLPYDPTHGEQR
                     YERFCAEYIPTLPPAYALNPDRRWDGQLPKLPMQRQLLYIAIFDSVCWNFRPLLLLKPG
                     QVTSLPPYKQVLLQSQKQKLALAALEELDAVTALHIMFGGSHTRFSAIIFNTFEAAVVL
                     LILCTQKDFPFDQGEDHPDILGLRVATLTRPRAMRAVEKALGRLQMLAEVSEMAASGAQ
                     VVTQLFAKAARMEHSLEPYTPNESSRSSSSPAILSNFLNLEDGSGLWMSSEDPTLMPDM
                     LSTIAHGDSYSMLQFPSLDLTSWNGNFHS"
     mRNA            join(16538..16589,16645..17491,17557..24085)
                     /locus_tag="CBS51388_009558"
                     /product="hypothetical protein"
     gene            16538..24085
                     /locus_tag="CBS51388_009558"
     CDS             join(16538..16589,16645..17491,17557..24085)
                     /NRPS_PKS="Domain: PKS_KS (11-437). E-value: 2.6e-148.
                     Score: 486.1. Matches aSDomain:
                     nrpspksdomains_CBS51388_009558_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (587-904). E-value: 8.8e-83.
                     Score: 269.7. Matches aSDomain:
                     nrpspksdomains_CBS51388_009558_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (984-1161). E-value: 5.8e-33.
                     Score: 106.2. Matches aSDomain:
                     nrpspksdomains_CBS51388_009558_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1728-2037). E-value: 9.5e-82.
                     Score: 266.2. Matches aSDomain:
                     nrpspksdomains_CBS51388_009558_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (2064-2244). E-value: 8.4e-44.
                     Score: 141.3. Matches aSDomain:
                     nrpspksdomains_CBS51388_009558_PKS_KR.1"
                     /NRPS_PKS="type: Type I Iterative PKS"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 215.4; E-value:
                     2.4e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="CBS51388_009558"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009558-T1"
                     /sec_met_domain="PP-binding (E-value: 4.9e-07, bitscore:
                     25.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.1e-81, bitscore: 269.7,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 3.5e-150, bitscore:
                     495.7, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 9.3e-40, bitscore:
                     131.7, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTPPRSNECEPIAIVGMGCRLPGGVQDIPALWEFLRDQKDAHGEF
                     AAPRFSAEGFYHANSDRPGTAVASSGFLLKEDPRLFDPSFFGITDVEAETMDASQRKLL
                     EVTYEAFENAGETWDSVSGSRIGVFVGDISFDNYVSQTRDWDYSGKYSATGAFPNMLAN
                     RIHYVFNLKGPSLLINSACTSAMYALHLAITSMRNGDCDSAIVAGSNWVMDPNCHIAMG
                     KLGALSPSSRSHTFDASADGYARGEGFAALYLKTVSLATQDASPIRALIRGSAVNANGR
                     TSGITNPSGPAQETVIREAYKNAGDLDPSETTLLECHGTGTRVGDPIEVTAAGNVFGPS
                     RSTVHEDRLVVGSVKTNVGHLEGACALPGILKVVASLEAGEIPATLGFQTPNPRIDFDQ
                     AKARVVNKTEPWPKDRLKRASVTSAGFGGTNGHCIIDHVHNVIPEYVKPGVIYEQVEQS
                     NGTNGHAVNGTNGTNGTHGTKPEALSQLHRPILHSPTLVRRADATTRQMVVLPFSAHNQ
                     SSLIANMEALQRSIPHHSLADVAYTLAAKRSRFSQRAFSIVDKDQVTQVGSVTDNGPKV
                     FASPQRVNVGFVFTGQGAQWPAMGAELFEYAVFRDTIAYLDTVLAVLPQPAPWKLVDIL
                     CGNCDKDLIQKPAVSQTVCTALQMGLVDLLASWSVRPAGVVGHSSGEMAAAYAAGRITA
                     AEAITIAYYRGYMVSFNQKKGAMLAVGLGADQGAEYVRQAGMEGRVKVAAINSPASITM
                     SGDADAIEQLSVQLTQEAIFNRQLRTGGLAYHSHHMLSFGHDYAQAVDDGLQRLASLGI
                     NDTTSRYSNIPWASSVVPQKSSTMPREEVTASYWKANLESPVRFTDAVSKLLDMDDLRI
                     GATVEIGPHPALKGPLGQIVKGLGRTIPHVASVERGQDSRRSLLGLAGTLFALNADVDL
                     VAVNAVDESHGAGKRTLIHGCMAIDLPPYRYTYGPIKYHESRLSKEYRLRRWPRHDLLG
                     ARVPGTTRLRPQWRNILRLKDLPWLNDHRVPPHVLHPGAAHIVMAMLAAEQAYAEFPDA
                     LPVAGLTLRNVSIKKTLVVPQDDKGIEIVLSMELEDGATAASPGWASFSIASVVNDSEQ
                     WTEHCSGLVKVDVVAFNAPAAIDTTTMDGRAVDAQAWYTRFADMGLQFGPSFQGYSDIW
                     ADPFSNVALAKLSLNTTAGLFPGGESRYPIHPASLDLVIRLGLMACNGGQAETASVQLP
                     IHFDQMRFKLGCLQGRDWITGVSRGELRGLRGAYAQLQLLDDSGEAILDVDNMRFTSLN
                     NEQQSSAQDFSGQAYSSPFARLVWRPDSRTLSRDQWNKLLASVDGTTTFSRLSYLIDLV
                     GHANPDLRILQLSAGSDDRNAGQAVLKSLVGHNGIKRYREYVATDTSAERLDSFRETVS
                     AFRDVRYSVLDISQDPSEQEFQIGTYDMILWSNVEHGPATEQALANAKKLLHPGGHLVL
                     VDRMNSSELAWDQCLRRVGFDSGYKLVCRETDLHSTIILSTLPDPVPTTKSGNPVVHLL
                     HGSQGTSALLHHLARAMEQHGLSIRISPMDQAINVLAPNSRVVAFLDGENLLFAADQRR
                     LGLFQHLAANTASMVWVTSCGLVKGRNPDGAFVSGLLRTLGTENPAGQFLSVDVDAEDF
                     QVPGLEMDELVRCLVEQELLLQPTLDDKGPPEVNRDLVWQDGCMWTSRIVPDGQLQGYA
                     EVAPTRQEVDVSSRPLSSLGPVRAAFETPGILTSLYFRPYTELLQPLPRDYIDVKVDAV
                     GLNWKDLGLCSGRFDANNLSNEYCGVVTQVGADVTRLSIGDRVYGMGKGHFGTHTRVPA
                     GLAQKLAADVNAIEAATMPLVYMTAVYAFEHVTRLKPGHKVLIQSATGGLGLAAIQLAR
                     SKGATIYATAGTADKVRFLTDHMGVPASQIFSSRDLASLNRATQQHGGFDVILSTAQGD
                     MLYESVKALAPLGHLVDVGRLDVTSSQTMGLELFQKSAGFTSFDLGLVVERDSVLGAEL
                     MQSVDAHFRAGHIGPIKPYSVADIGYLDQTLLQFSQGTHIGKRVITYQDPSTLLRTLPT
                     SSATPARFDPAARYILVGGLTGLGRSIVRWMSSRGARDMEVWSRRGASNLAPEAQRMIT
                     ELAAQGIRVQPVACDVTNRDAVLHTMRSAHVDPTRPVRGVFHFAVSYQDISFDKMTEAQ
                     FNQGMAAKVFGVKHLHDATTSIPLDFFAMTSSLGTVYAFPTQSTYLAANNYLDYFARYR
                     RRLGLPATTVALGFINDLGPLTNDPVTVNLFVRAKGQTMTGAQVVRMLEPAFVNEQPNA
                     LWLGHTDDPLSASHIVTGIDPAVLAKMARSSAASLASSTIPRWYHDSRVSLMLRALEDA
                     SSATSSLSSSDIHASDASPTAQLRRQFDHSVATLRAGGKDSKEDAWTETIKFVTEAIQA
                     TVAGMLFVDVGSVNPNKTVAEHGIDSLLAAEFRNWFQGAFGRGVSMLELMDARMSLALL
                     ARSVVEGAVGV"
     aSDomain        join(16571..16589,16645..17491,17557..17968)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBS51388_009558_PKS_KS.1"
                     /evalue="2.60E-148"
                     /label="CBS51388_009558_PKS_KS.1"
                     /locus_tag="CBS51388_009558"
                     /score="486.1"
                     /tool="antismash"
                     /translation="IAIVGMGCRLPGGVQDIPALWEFLRDQKDAHGEFAAPRFSAEGFY
                     HANSDRPGTAVASSGFLLKEDPRLFDPSFFGITDVEAETMDASQRKLLEVTYEAFENAG
                     ETWDSVSGSRIGVFVGDISFDNYVSQTRDWDYSGKYSATGAFPNMLANRIHYVFNLKGP
                     SLLINSACTSAMYALHLAITSMRNGDCDSAIVAGSNWVMDPNCHIAMGKLGALSPSSRS
                     HTFDASADGYARGEGFAALYLKTVSLATQDASPIRALIRGSAVNANGRTSGITNPSGPA
                     QETVIREAYKNAGDLDPSETTLLECHGTGTRVGDPIEVTAAGNVFGPSRSTVHEDRLVV
                     GSVKTNVGHLEGACALPGILKVVASLEAGEIPATLGFQTPNPRIDFDQAKARVVNKTEP
                     WPKDRLKRASVTSAGFGGTNGHCIIDHV"
     CDS_motif       17298..17336
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBS51388_009558_0001"
                     /evalue="2.80E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="CBS51388_009558"
                     /score="13.9"
                     /tool="antismash"
                     /translation="FDASADGYARGEGF"
     CDS_motif       17600..17644
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBS51388_009558_0002"
                     /evalue="6.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="CBS51388_009558"
                     /score="12.0"
                     /tool="antismash"
                     /translation="LECHGTGTRVGDPIEV"
     CDS_motif       18416..18466
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBS51388_009558_0003"
                     /evalue="1.60E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="CBS51388_009558"
                     /score="17.3"
                     /tool="antismash"
                     /translation="FVFTGQGAQWPAMGAELF"
     aSDomain        18419..19369
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBS51388_009558_PKS_AT.1"
                     /evalue="8.80E-83"
                     /label="CBS51388_009558_PKS_AT.1"
                     /locus_tag="CBS51388_009558"
                     /score="269.7"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mxmal"
                     /specificity="consensus: pk"
                     /tool="antismash"
                     /translation="VFTGQGAQWPAMGAELFEYAVFRDTIAYLDTVLAVLPQPAPWKLV
                     DILCGNCDKDLIQKPAVSQTVCTALQMGLVDLLASWSVRPAGVVGHSSGEMAAAYAAGR
                     ITAAEAITIAYYRGYMVSFNQKKGAMLAVGLGADQGAEYVRQAGMEGRVKVAAINSPAS
                     ITMSGDADAIEQLSVQLTQEAIFNRQLRTGGLAYHSHHMLSFGHDYAQAVDDGLQRLAS
                     LGINDTTSRYSNIPWASSVVPQKSSTMPREEVTASYWKANLESPVRFTDAVSKLLDMDD
                     LRIGATVEIGPHPALKGPLGQIVKGLGRTIPHVASVE"
     CDS_motif       18665..18760
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBS51388_009558_0004"
                     /evalue="4.20E-08"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="CBS51388_009558"
                     /score="25.8"
                     /tool="antismash"
                     /translation="VRPAGVVGHSSGEMAAAYAAGRITAAEAITIAY"
     aSDomain        19610..20140
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBS51388_009558_PKS_DH.1"
                     /evalue="5.80E-33"
                     /label="CBS51388_009558_PKS_DH.1"
                     /locus_tag="CBS51388_009558"
                     /score="106.2"
                     /tool="antismash"
                     /translation="HDLLGARVPGTTRLRPQWRNILRLKDLPWLNDHRVPPHVLHPGAA
                     HIVMAMLAAEQAYAEFPDALPVAGLTLRNVSIKKTLVVPQDDKGIEIVLSMELEDGATA
                     ASPGWASFSIASVVNDSEQWTEHCSGLVKVDVVAFNAPAAIDTTTMDGRAVDAQAWYTR
                     FADMGLQFGPSFQGY"
     CDS_motif       19694..19771
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBS51388_009558_0005"
                     /evalue="4.60E-06"
                     /label="PKSI-DH_m2"
                     /locus_tag="CBS51388_009558"
                     /score="19.2"
                     /tool="antismash"
                     /translation="WLNDHRVPPHVLHPGAAHIVMAMLAAE"
     aSDomain        21842..22768
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBS51388_009558_PKS_ER.1"
                     /evalue="9.50E-82"
                     /label="CBS51388_009558_PKS_ER.1"
                     /locus_tag="CBS51388_009558"
                     /score="266.2"
                     /tool="antismash"
                     /translation="LTSLYFRPYTELLQPLPRDYIDVKVDAVGLNWKDLGLCSGRFDAN
                     NLSNEYCGVVTQVGADVTRLSIGDRVYGMGKGHFGTHTRVPAGLAQKLAADVNAIEAAT
                     MPLVYMTAVYAFEHVTRLKPGHKVLIQSATGGLGLAAIQLARSKGATIYATAGTADKVR
                     FLTDHMGVPASQIFSSRDLASLNRATQQHGGFDVILSTAQGDMLYESVKALAPLGHLVD
                     VGRLDVTSSQTMGLELFQKSAGFTSFDLGLVVERDSVLGAELMQSVDAHFRAGHIGPIK
                     PYSVADIGYLDQTLLQFSQGTHIGKRVIT"
     CDS_motif       22145..22189
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBS51388_009558_0006"
                     /evalue="1.80E-03"
                     /label="PKSI-ER_m4"
                     /locus_tag="CBS51388_009558"
                     /score="11.8"
                     /tool="antismash"
                     /translation="AATMPLVYMTAVYAFE"
     CDS_motif       22214..22276
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBS51388_009558_0007"
                     /evalue="1.00E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="CBS51388_009558"
                     /score="27.5"
                     /tool="antismash"
                     /translation="GHKVLIQSATGGLGLAAIQLAR"
     CDS_motif       22286..22336
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBS51388_009558_0008"
                     /evalue="7.10E-05"
                     /label="PKSI-ER_m6"
                     /locus_tag="CBS51388_009558"
                     /score="15.5"
                     /tool="antismash"
                     /translation="GATIYATAGTADKVRFLT"
     CDS_motif       22850..22921
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBS51388_009558_0009"
                     /evalue="7.30E-10"
                     /label="PKSI-KR_m1"
                     /locus_tag="CBS51388_009558"
                     /score="31.4"
                     /tool="antismash"
                     /translation="YILVGGLTGLGRSIVRWMSSRGARD"
     aSDomain        22850..23389
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CBS51388_009558_PKS_KR.1"
                     /evalue="8.40E-44"
                     /label="CBS51388_009558_PKS_KR.1"
                     /locus_tag="CBS51388_009558"
                     /score="141.3"
                     /specificity="KR stereochemistry: (unknown)"
                     /specificity="KR activity: active"
                     /tool="antismash"
                     /translation="YILVGGLTGLGRSIVRWMSSRGARDMEVWSRRGASNLAPEAQRMI
                     TELAAQGIRVQPVACDVTNRDAVLHTMRSAHVDPTRPVRGVFHFAVSYQDISFDKMTEA
                     QFNQGMAAKVFGVKHLHDATTSIPLDFFAMTSSLGTVYAFPTQSTYLAANNYLDYFARY
                     RRRLGLPATTVALGFIND"
     CDS_motif       23234..23344
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CBS51388_009558_0010"
                     /evalue="5.60E-13"
                     /label="PKSI-KR_m4"
                     /locus_tag="CBS51388_009558"
                     /score="41.4"
                     /tool="antismash"
                     /translation="LDFFAMTSSLGTVYAFPTQSTYLAANNYLDYFARYRRR"
     mRNA            complement(join(24155..24170,24414..25111))
                     /locus_tag="CBS51388_009559"
                     /product="hypothetical protein"
     gene            complement(24155..25111)
                     /locus_tag="CBS51388_009559"
     CDS             complement(join(24155..24170,24414..25111))
                     /codon_start=1
                     /locus_tag="CBS51388_009559"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009559-T1"
                     /transl_table=1
                     /translation="MHILLAFSGFHLVRRSDDQQWSQSMGFTEAEIYTEAERHFNVAIR
                     DVSATLPHLDRDNSPAMYASAIFIFISSLARGPQPGEYLAFRSDGTPGHLSLFLGVRSV
                     FELCSGDMPTSVFSIHGEGDDSSSRTTPQTEHENSHIASQNKTKLEDYPHHLETYRALL
                     TTTIPIDDPRLSIYLQTLDRLGHSLDAIMGPDPQGTMGMALFPLVFAWLYQLPDAVVGD
                     LQRREPVALILKMRV"
     mRNA            complement(join(26075..26496,26564..27166,27226..27294,
                     27364..27466,27537..27860))
                     /locus_tag="CBS51388_009560"
                     /product="hypothetical protein"
     gene            complement(26075..27860)
                     /locus_tag="CBS51388_009560"
     CDS             complement(join(26075..26496,26564..27166,27226..27294,
                     27364..27466,27537..27860))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 114.5; E-value: 9.8e-35)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CBS51388_009560"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009560-T1"
                     /sec_met_domain="p450 (E-value: 1.9e-36, bitscore: 120.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MENMLGYTSMPVPVLVSLALGLAFLLLQSFRYKDPALNPKKPFEL
                     TSTRVKQEYFSNARRLLWDWFTTHSNTPVLLHTDTGKVTILPPSMANEIRNDDRLSFSR
                     WTFEAFHGNLPGFDGFREGSQDSGIVQAVIGNDLTKYPNKVTEPLANETSVAVRELLTD
                     NEEWHTIQLRTVMVALISRISSRVFLGEKLCRNEEWLRVTQDYTTDGFLAAEELRMWPA
                     AIRPIVHWFLPRCRKLRAQVKVARKVMGPILEERRQFKKHLHAEGKQSQGFDDAIEWFE
                     KAAKGRPYDPVSAQLILSVAAIHTTSDLTSQTMTHLVQNPEILEPLRKEIVDTLQQHGW
                     KKTALYNMKLLDSVIRESQRLKPINNASMRRVALKEVKLSDGTVIPKNGMLAVSAHKLW
                     DDDTYENAAAWDGYRFYKMREDPERQTKAQLVTTAPENLAFGHGKHACPGRFFAANEVK
                     IALIYLLLRYDWKLLEGTVPKIRYGGFSMAVDPSLKMEVKRRREEMGI"
     mRNA            complement(join(29633..29795,29857..29974,30056..30215))
                     /locus_tag="CBS51388_009561"
                     /product="hypothetical protein"
     gene            complement(29633..30215)
                     /locus_tag="CBS51388_009561"
     CDS             complement(join(29633..29795,29857..29974,30056..30215))
                     /codon_start=1
                     /locus_tag="CBS51388_009561"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009561-T1"
                     /transl_table=1
                     /translation="MVVHMVMDEFLLHAVTFGAAVCLITTRTLKIIPREIPDVEARKRI
                     QSVALFGCASFIFGYLVWLIDEFVCQSLIVARHAVGLPVAFLLELHGWWHVFTAIGGYI
                     AVAVIDLITSGEVQRDSVAQLAWPLPTVARLLGPAAGETKRE"
     mRNA            complement(join(31695..32066,32120..32232,32296..33115,
                     33169..33326,33382..33688))
                     /locus_tag="CBS51388_009562"
                     /product="hypothetical protein"
     gene            complement(31695..33688)
                     /locus_tag="CBS51388_009562"
     CDS             complement(join(31695..32066,32120..32232,32296..33115,
                     33169..33326,33382..33688))
                     /codon_start=1
                     /locus_tag="CBS51388_009562"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009562-T1"
                     /transl_table=1
                     /translation="MRSLVYLLALAGLTTKSLGQQKQQQPLSATAKPNVVFILTDDQDA
                     HLASLDYMPYVQKHLLDKGTHYRSHYCTTSVCCPSRVTLWTGKLAHNTNVTDVNPPHGG
                     YPKFISQGLNDNYLPVWLQEAGYNTYYTGKLFNVHTVDNYNAPFPAGFTGNDFLLDPFT
                     YDYLNSTFQRDHEIPQSYEGEYSTDVLAQKAYRLLNEAVTAQKPFFLTVAPIAPHCNVF
                     MNGTGLDANPKFSFSAPIPAKRHEHLFPDVKVPRTPSFNPEIPSGANWIKTLKRQNDTN
                     VDYNDHFYRQRLRTLQAVDELVDGLFTRLKEYNILDNTYIVYSSDNGYHIGQHRLQPGK
                     SCGYEEDINVPLIIRGPDIAQNVSTDIVTTHTDLAPTFLELLGIPLREDFDGNPISLTR
                     SQIERAQEERQEHVTVEYWRYAAGEGIYDFDLSAYNNTYKALRIKGIGYNLYYSVWCNN
                     EHELYDMTTDPHQLHNLLSAIEQPSATSHTILNVDLSKVVQRLDSLLLVLKSCKAQVCV
                     KPWDALHPRGEVMTLKDALDVHYDHFYEVEQTTRVQFNECARGYFLDAEGPQFDSGTDY
                     EVLRDGLPWYEWV"
     tRNA            34382..34455
                     /locus_tag="CBS51388_009563"
                     /product="tRNA-Ile"
     gene            34382..34455
                     /locus_tag="CBS51388_009563"
     mRNA            36678..38198
                     /locus_tag="CBS51388_009564"
                     /product="hypothetical protein"
     gene            36678..38198
                     /locus_tag="CBS51388_009564"
     CDS             36678..38198
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 96.6; E-value: 2.1e-29)"
                     /gene_kind="transport"
                     /locus_tag="CBS51388_009564"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009564-T1"
                     /transl_table=1
                     /translation="MTSKSAGLSAAEPIFPQIPRVALVPQDDASSPLSSLELHSIEPIG
                     ANTPHSRRTRHAGSTKPSEVDEMFNVVQSAAAENYGAQDTNRKTASIHPRRNTIWRLAS
                     ACLMNFGNGMNDSAPGALIPYIEDDYGIGYAIISLIFIANAVGFVLAAPLTHTIQARIG
                     HAKSYALSMSLVTAGYVAIVCHPPFPVVVTAFLLLGFGMALSIALNNVFCANLNSYATA
                     LGFFSGAYGIGGVISPLLATAMVSHGIRWTYFYFITLVISTLNMLLAAVVFRNYKDEGA
                     ASRAPTQQTSPSLASQTAQPNENDSHNSHTRLQTLKRAIRNLTTILGSLFIFAYQGAEV
                     SISGWIVSFLINYRGGDSRRVGYVSAGFWAGITLGRFLLVYPANRIGEELAVGLLVVGA
                     IAFQLMTWLIPNIVGEAVAVAVVGLLLGPMYPCSTAVFAKLLPRSIQLTSMSFITALGS
                     SGGAVFPFLTGILSQEVGTIVLHPICLALYAAMVVCWCFLPAISKRSE"
     mRNA            complement(join(39367..39785,39902..39932))
                     /locus_tag="CBS51388_009565"
                     /product="hypothetical protein"
     gene            complement(39367..39932)
                     /locus_tag="CBS51388_009565"
     CDS             complement(join(39367..39785,39902..39932))
                     /codon_start=1
                     /locus_tag="CBS51388_009565"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009565-T1"
                     /transl_table=1
                     /translation="MRQNQMADGNHRTVGAVALWIPSTLLGSTLHDLVAAKGCFIVFTI
                     FYGLFASAYIGLFSPALVELFGLQEMPRITGIMYMVQGAAGLVGTPVAGVMVRTYNGET
                     TSRSYLDMAIFVSALMVASTMTVAWARMEQGFDRVSGHLTWKWKL"
     mRNA            40544..41500
                     /locus_tag="CBS51388_009566"
                     /product="hypothetical protein"
     gene            40544..41500
                     /locus_tag="CBS51388_009566"
     CDS             40544..41500
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081:cysteine synthase (Score: 262.9; E-value: 5e-80)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CBS51388_009566"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CBS51388_009566-T1"
                     /transl_table=1
                     /translation="MSLIPSVDSALDAIGNTPCVQLTRVVPQDCARVFIKLESLNPTGS
                     YKDRMALSVIEEAERRNDLRPGMTVVEATGGSTGSSLAFVCAVKGYTFRVVSSDAFAKE
                     KLNTMTAFGAHLDIVPSENGKITPQLIPSMRERARRIATEDKDPSSYYYADQFSNPDVF
                     PGYETLGREILAQVGEPIDAFCGAVGGAGMVMGVGKTLKQSWPACHVAVLEPASAPALT
                     KGHGGEHSVEGIGIGFPPPLLNKDWYDEARAIDEREGRSMCRRLAREEGLLVGTSSGLN
                     VVAAIQLAKELGPGKTVVTVGCDTGLKYVRGNLYTDS"
ORIGIN
        1 atgaaactct caaccttcct cttctctctt ctggctacaa gccaggtcac tttagcgaca
       61 ccaattccaa tagtggatgt tgctgaactt ccttcagaca ccggtcttga aatccgatct
      121 cctaacccgg ctgacgagct gctggcgatt ctagagcagc gggatactag agtctgtgag
      181 atacttaatc gaacgattcg ttctattggt accagcaaat ttacgtatgg cgcatgctct
      241 cctctcgatc aacaataatc ctcaagggac taataatttc tagggtcgtc tatatcgtga
      301 tgggctcacg tcttgctcga caagtctgtg aatatgccgg tggcagtaga tgtgaggaaa
      361 tatcttatat tatttcagac ggtctcctct tggcctatgt tgctgccgcc cattactctg
      421 gagccattcc cgaaggtcta ccgggtaagc gtgacgtcga tgtctcccag gattatttcc
      481 agctgtggga gactatgctg tcaagtagtg gagatatctc ctatgattat ctcactcctc
      541 tctcgaatac ctcaaatact cttcccttgg ttagacgcca ggatcagcct ttaccgatcc
      601 acagaattca gattactggt ttcgcccata ataactctcc gaagcacgat atcatcgcca
      661 atcactatga aaatggtgac accgttcttc aacttcctct tgcaggaggg gttcctggtg
      721 ctaatgacac tgaaggactt gatttgagga agcggtttga caacccgggg tttaagattg
      781 cgttcactac caggggtaga tcacagctca ctcaagccca tcaaaagtct atggcactgg
      841 caggagctgc tacatgggct gtctatgcag acaatgccaa tcacaagatg gatgacttca
      901 tcggttttgc tgagactgat catgcggcta acttctacta ccgaatcatt ccggagctga
      961 gaggattcgg aactaattac gagactgttg atatttgtgg gggaatggca tcgtacttgt
     1021 gaagagattc ggcaaatggt gaggtcgctg tcgtggatat gaaccgatca tgcattgctt
     1081 gtcaatgcat ccatcatcgc actgacgacc agtgaggaag tgatacgtgc acgaatttat
     1141 gaccgcatat ggaaagaaag aaatgaaggt catattaccg ataaggaaaa agttgctagg
     1201 gtcagtgtgg gtacgggctc agttttcatg catgaagggc agtcgctttg gtttgcaatt
     1261 gacctgacat gcatcatgta tgatataaat cctcatatta ggaggtgtga gaagggaaaa
     1321 ctcctatact actaagacca gaacaagatt ataactaatt taaatcctat atgaaaacct
     1381 tttttctatt ctccatatct aaacaagcaa agcaacaccc agagtaccag tatataccac
     1441 ataattcgca catacaacct agtataacaa cagcactaag cattaaggcc gatgccgatc
     1501 gcttgtggct tcccgccggt ccctctcgcg cactggccac ccattcaaac cagagacaac
     1561 agctaggaag tgtctagata aaacttgtct aatgcattgg ctataatttt aattttttcc
     1621 gtaggtatga gatgggcaga tatgcgacca agaggggcat gaagtgcgga gttgagtcag
     1681 tctgttgagg taggttaaat gagtctcctt ctggtagaca cttcactcga gtctgtcccc
     1741 gtgacatctc cttcggagtc tagtcttttc atctcgctgt atcagaaacg aactcaatat
     1801 tgataagatt acaggtatgg tcttccctga ccttccctga ccatcacagc agctgatgat
     1861 tccctatgac acaggcgctg tggggaccgg ccgtactaac tagtagacgt tagtacttag
     1921 tagagatcaa ctaatccata agtgtagagc tgacactgcg ccagttctac ttagcgtggg
     1981 ggcctttcca gaccccagtg agttgtcact ctatttatgc cggatcaccc gagccatgat
     2041 ccctgctctt ctccaggttt caaattccta gattcagtct gtccttccac ctgcccctcc
     2101 gcaatgacca caatcaacgg tcactgcgat ccggccttca ccggggtgcg cgatctccta
     2161 cagcaattga tcaacaatga agaagagcta ggagcatcca tctgtgtcaa catcgacggt
     2221 caaaacgtcg tcgatctctg gggcggccac gcagacccag cgagaaccaa gccatgggaa
     2281 aaggacacac taaccgtggt atggtccgtt tccaaagtaa ttaccgccat cgcaaccaac
     2341 attctcatcg accgtggcct cttagaccca aatgagaagg tctccaaata ctggcccgag
     2401 ttcgctgcga acggcaagga gaatatcctt gtgtcccaga tcctcagtca cacctctgga
     2461 gtatcctcct gggagcttcc caacacctta gacgacatat acgatgcgaa aagaggagcc
     2521 gataaactag cccgacaggc cccctggtgg acgcccggcg aacactccgg ctaccacgta
     2581 accaaccagg gccacttact cggcgagctg gtgcatcgtg taaccggaaa accgttggat
     2641 gagttcatcc gcgacgagct tgccagtcct ctggctgcgg acttccagct cggggtccca
     2701 gagaaggact ggccacgaac agcagacgtt tccccgccgc cgccactgag tctcgacggc
     2761 gttgacccgc agagtgttat gttcaagagc tttgccagtc tgcctatacc ggcggaagaa
     2821 agtatgagtc ctgggtttag gaaggcgttg attggtgcca cgaatggatt ctctaatgcc
     2881 cgaggcattg cgcgcattgc gtcggtcatt tcgcttggag gcacggtgga tggaaagcag
     2941 tatctctcgc ctgaaactat tgaccgcatg ctggaggagc aaataagtgg gccagatttg
     3001 gtcttgatgt atcatttgcg ttggggtctt ggtgttgggt tgcccgtccc ggagactttt
     3061 ccttggttgc ccgacggtcg cattgctttt tggacgggct ggggaggttc agttgttgtt
     3121 atggacctgg agaaacggat gacgattgcc tatgtgatga ataagatggg acaaggcacg
     3181 ttgggttcgg ataggacggc ggcttatgtg cgggctgttt atgattgtct tgcatagata
     3241 gtatgttaag gctcgcgaat ggaacacgat atataaactg aaaatagtca agcggttcaa
     3301 agtctgcgcc cctccattgc gaacactgat tagaagtagt aggctgtctt gagttcttgt
     3361 gtagaacata gtggtttggc aggagaagtt tcatttgaaa aaaaaaaaaa ataaaaaaat
     3421 aaaaaactaa aggtgtctac gttcgttgtg actgatgggg tggttgtacg ctgccgaaaa
     3481 aacaaaaggg caaaaaagaa tgaccagact ggggctcgat cccaggacct tatcggtgtt
     3541 aacgatacgt gataaccaac tacaccatcc ggccaattca atgaaagtga ctgtcactta
     3601 aagactcatt atcctataga aacgattccg agaagttctt gttggttagc ataatcgttg
     3661 ggtcggctgt gctgatttag gctgcgacat agcggtattg gataagatct tcacgccgct
     3721 ctcctgagtc ggatccaggc agagctttaa tcggtgggaa agattcagag ctctttcaaa
     3781 ctaagacgta atgcatctgt aagtttgtaa acattgacat ggttcgaatt ctcaaggtct
     3841 ctaaataatt ccagacttgg aagcgctcca actgagatta agctcaggcg attacccaga
     3901 ccgccgctgt tagcataaga cacgatatga cgggctttga aataatacct ttagcattgt
     3961 atccaagata ctgatctgaa ttatgaataa acaatatcgg gtttcagtct agcaggttga
     4021 ccttactact tcgcccgagt cataagtaga ttcttcgtga cctcttactt ggctctcatc
     4081 cgttctatgc ttcgccctgg caagacttta gctatagttg cactaagcta tacaattgat
     4141 gctaggtatt atgaatcagt agatgaatca aaggctctaa gagtacataa agatataaat
     4201 tctacatggg cttttggtac atgggtataa tttgggcggc ctcgtagcct aaggcagagt
     4261 tgtgcgtcgt cagcttttag cgcgccgaac tcaaccaact ggtagtagtc atcctgcgca
     4321 gcacgtcagc cttgtgtact tggtgccttc tactcatcaa cttagagatc cccggaagtg
     4381 ctactcgact aaacaagagc agattctctc tagtcggtga aggcacctca cgatgtcggg
     4441 aaatgacgta ccttcttacg atgagtttgc cgtgggctgg atctgtgccc taccactgga
     4501 gatgaccgca gctaaagccg tcctcgacga agaatatcca agtctacatt tacctaagca
     4561 gcatcacaac acctacgtgc ttggaaggat ttccggacat aaagtggtga ttacatgtct
     4621 tccattcggg atttacggaa ctacgtcggc gactgcggta gttgagcaga tgctattcac
     4681 ctttcggtcc atccgctttg gcctcatggt cgggattggc ggaggagtcc cgtctgctgt
     4741 cgatgtcaga ctgggagatg tggtcgtaag taagccgact gctggccttc ccggagtgat
     4801 ccagtacgat tatggcaaga ccgttgcttc aggtcgcttt gagcagaccg ggacactcaa
     4861 caagccgccg atagttctcc tatcagcgtt gtcgtcgctg gaagcagatc gtctggctgg
     4921 aggcagcgac attggtacct atgagaagat tatcgcggat tctctaaggg ctgccaaaga
     4981 tccatccgtg tttcggtatc cgggtgccga acatgattgg ctcttcgatg cctcctatga
     5041 ccatgatcct cgcttcgcat cctgtgctga gtgtgaccca gaacgacggg tgagacgcaa
     5101 gcctcgacgc tcatgcacac cggtcgtaca ttatggcaac attgcgtcgg gcaatcaagt
     5161 catgaagcat ggcctcacgc gcgatcgcat tgcgcagaca acacagggga tcttgtgttt
     5221 tgaaatggag gcggcgggga tcatggatta ccttccgtgc ctcgtgatca gagggatttg
     5281 tgactattct gactcccaca agaagaaaga gtggcagggg ttcgcggctt tgacagccgc
     5341 ggcctatgcg aaattgctat tgtcgaagat tcctgtccat cggagtgagg cgtctacgct
     5401 gatacaggca cctggttcga agaatagtag tacgtggggc ccaagcatgg tgtactttat
     5461 acccagagag ctattactga tgttaatgaa ggcgattcgt tcgatgttcg cttcgacaca
     5521 atcgaaatgc cacaggctgc catttctgtg ggccgggagg cagagcttgc aatgataacg
     5581 aagagtcttc tatcagacag atttcgaggc attgtcaccc tatatggaat gggtggaatt
     5641 gggaaaaccg aactctcgat tatgtacatc atgcgccatc ggcaaaagta ttcatctgtc
     5701 ttctggattg atggtagcag tcttgacaag ttatattcca gctatacaca agcggcaatg
     5761 cggatcatac atgatcatcc aggtgaccag tctttgagaa aggccttgaa ggaaggtgat
     5821 cagattcaat tggttggatc agtcaatgag tggctgagtc gcccttcaaa caatcggtgg
     5881 ttactcatat acgatggctt cgaccttcct atggtcgaag gttttgacaa agccgaaatc
     5941 atgaaaatga gactgcctcc aagcaagcag ggtcatatca ttattacaat gagaagttat
     6001 gatattggaa taggtgatca gattcaagta agaaagctgg cagcaattga tgacggcctc
     6061 gatcttctga ctcatgtgtg cggacgaccg aatctacgag atggcaagta acccgtcgtc
     6121 cctgctatgc atttctatta acagctgact ggtactactt agacccctac atcgcagaac
     6181 tattaactca gctagatggg ctgccactgg ccatcgtgtc tgctggggcc tatctcaaac
     6241 agagtgtgat aacttgccgc gagtatctca aattatataa agaatcttgg ctgcagttac
     6301 aacaactatc gccgcagcaa tcttcgcttg aacaaaagtc aatgcataca acgtggaaaa
     6361 tcacactaaa ccagattatg cgccagcata gacatgccgc cgtactgctt aagcagtgga
     6421 tagcttttaa tagtaacgat atctggtatg gcctcttcca gagtgctcga ccagaatcag
     6481 cgtccgaccc cttagtgttc gatacagcaa tggctgtgct aagtaggtat ggatgggtcg
     6541 aaccagggcc tgtcgcagca ggaaattctc agcagggtcg gggctatagc cttcaaaaat
     6601 gcattcatgc ctggcttcaa tacgaggact gcttcgtgtc agatattgac ctgctaacgc
     6661 agcttgcagt tttgaagatc agtacttacc agttggatct ggtcaccaaa ttcaattttt
     6721 tctcactgga actccctgat agaaaccgtc ttcttcctca tgcagaccga tgcctggaaa
     6781 tctatctttc tagcggcaag gataaataca acagcctctt tgatctgaaa gcgcagttac
     6841 gacttgccga tttatatatg atttggagta cccgggcctc acccatctat acttgctatc
     6901 ttgatttcct gtgccagcca tatgaggaaa agcgaaatct ggccaaatcc caggacctct
     6961 actgtctcct aatggaaaag cttgatatgc aacaggatca gtcgaacagg gaagtgcaag
     7021 atatgatgtc caaggtgtat caccagcgcg ggcttatcat gtttcgcaac cagcagtttg
     7081 tcatggccag caagatgttt cgattgtcta tccatagtaa cgctccggct tatgtctcac
     7141 atataaagct gacgcagttt ttgagcgggc caatttttct tatcccacta aatgggctta
     7201 tcttctatat tttacttcga gaggaagact tcaggaagga cgtcccgcta aatatgttgc
     7261 tgctcttcgt gaaaccaatt gtgtttcttc acttattgat atctcaaagg atgcaacggt
     7321 ggaaaacctt gttgctgtgg gcagttggcc acgcctgttt ccaggtgtat tactcgtcaa
     7381 ttcagcctac gcttaattgg ggggctttca tctgcggaac atatggagag gtagcaattg
     7441 tattgctgct aatgccaatg ctcttccgtg aggggattta ttaatccttc tctttgatcc
     7501 gccccgcaga gacgaaaaag cgaaaaatac gacgtacatt gtggctaata tgaagcattt
     7561 gcgtgtaaat tagcgtgata tatcttcttt cccgctcata cctttcatat ttgagccata
     7621 ccatattcac tcaatttata ccctagcatc actttatttt cctctatacc tccaccccgg
     7681 acaagatatc tacccaaaca acctctccct cctcatcccc agcgaactca ccacccccac
     7741 cgctccggcc accaacggaa taataaacgc cctggccatc gcatccgtaa tagccttgat
     7801 agcccgatcc ctcaactccc cactcaagct cttcaacaac gtactctgca cacccgctac
     7861 agcattccgt atctccgcct cactatatcc cctcccatcc aacacccctt tcagattctt
     7921 tactgcagta gactgaaaca cctgacttgc caccacaaga cagataactg tagctccaat
     7981 ctgcgccaca ttctgcaaat tgatcgcgct gaagatatcc tcgggaggca ccttgagact
     8041 agctaccgca taccccagct gcatggtcat gccggtgccg acagccatga ggatcgtgaa
     8101 accgtagatc tgtcctgccg gggtagaggg tgagaggtat ccgacaaaga gggcgctggc
     8161 gagggtgagg aggatgcctg agatgaggca cagcggcatg taatatttgg cttttgggag
     8221 gagccagccg atggcgaggt tgatggtgat cgttacgagg aggtagggga gaaggcgcac
     8281 ggcagccatt agggaggagt cgttgcgcgt gaactggaag tagattggga tgtagaaggt
     8341 cgtgaagaac atggcggtgt tggcgcaggt cgttgtgatg tagaggagga tttgggtgcg
     8401 ggagcggagg agatggccgg ggaaggagcg cgtttggggc gtagtgaaga tgcataagta
     8461 ttgttggagg gcgtaaagga tgaataggac gccgaagagc acgattagcg cgatggtggc
     8521 gccggagtcc cacgcccaga tgcctcctgc agagatgaag ccaagtgcga aggtcaccca
     8581 cattgccgcg ctgaggacga atcccagata gtcgagtcgc gttaagcgtt tgcgaagaga
     8641 ttggcccgcg ccggggtgaa tggcggggag gtagaagagg tacacggggg ctgtgatggc
     8701 gccgattacc aggttcaggt aaaaacccca gcgccaggtg gcggaggagt cggagaatcc
     8761 gcctcccacg acgggaccca ggatggcacc cacgccccag acaaatccgg ttcctgtaag
     8821 ataggtgccg cgctcgttgc gggtggtcat ggcagagaaa tggttaagtc caccgagata
     8881 gattcctgta cctccagcgc ctgcaatcac acggccgaca ataagggcgt tcatatttgg
     8941 agcaccacca cagagagcag aaccaccttg gaataacacg attccagcaa tgtagagcca
     9001 cttcatattc atgacggtat agagaaaccc gtaggggaga atcacggcaa ctgaaccgag
     9061 tgggaaaccg gctccaatcc atgcaagttg cgacacgtcc ccgaatctct caatcacggc
     9121 gccctgcaca tccgcagcga tggttgtatc aagtccatac atcagagcag agagatacag
     9181 agcagcgcaa atcagaaacc atcggaaacc ggtaatcttg cggacatcat catcggtggc
     9241 actggcgtcg gcgtcatgtc ctttctcatc ggactcttcg cgatgaggga gatgattatt
     9301 cacagcgaag tctgattcct gactcgaggg cagtgaatgc gctgcagctt ccattttggc
     9361 gaacccgaga gggctattgt ttctcgttgg gaggactgag cggctgggga ggatcgcgca
     9421 tatgtatagt gtcgagacag ggcagatcac ccattgcttc tccttatgtc cgttatgacc
     9481 ggcggaccac gtcgtggatt aaccacgcca gggacactgc aggacaaata gtctctaaaa
     9541 acgaagctct agtgcttcca cgatggcggg attaggagtt tagcattgtc tatccccgtg
     9601 ggaggccggg ggatcatcat ataacaaaca cgtcgctcac ccgaaattcg tcggccgaag
     9661 atagaatggc ccacgcactc acccgacaaa gagcacaatg catccgagat caccccaacc
     9721 aacaaccgga gcacgcactg gctccaatgc aaattcaaaa ctcatggact attgccaaaa
     9781 tcctgcccga tggcaaaatg cagatcgtcg accggcccga aggattcaca ctggatacag
     9841 ctctcgggtg gcgcccatcc acgaaacgta ggtagcgatt tgcttataag cttagaagcc
     9901 tttcattggg gttgatctga acctaacaga aaggaaaaga aggggatttt gttgtggcta
     9961 aacacacagc aagaagaaga aaaattacct gctaggtcga cacagggcta cgtttcgatg
    10021 atcagggtct ggaacatgta tactaatgtc gtactatttt ctctcatcat tactggacaa
    10081 tacgagtagc caatttaaat tgcatttcaa atatcctgag caaactaagt gcgctgggta
    10141 cagaaacatt ggcctcgggt tgcagcgcct gcttgttatg cgcttaccgg gatctcagac
    10201 gcaaatatcc cttcttggcg cggtaggaga tgtcgtaggt tgcctcatga ccagccaatg
    10261 cctcaggtac atcgagaaaa tcaaacttcc aagtcatcat gacagtcatg atcctcatct
    10321 ctagctgagc cagtcgccgc ccccagcaag cccgaatgcc cagcccgaac gccaactgcg
    10381 ggtacgacga gccatcaaac tcgagttcac cgcgctcatt ctggactagc caacgctccg
    10441 gatcaaatgc ctcaagatca gggttaccac cacctgggta cttccgggtc gtcttcacgt
    10501 cactccagta cagggaggat ggcgaagagg agtagtccgg tccctgacag acgagaagga
    10561 cgaccgtgcc tttcgggatc cggcggccca gaagctctgt gtcacgggta gcgtcgcgag
    10621 gaacaagcat ggcagcgcga agccgcaagg tctcctccaa tactgcgtcc aaatacggga
    10681 gtcggaattg gatgatctca gctgcagtgg gtaggcgacc ctcttggact gcggccgcgc
    10741 atactgtctg cagctcgtcg cgaagccttg tctgaacggc aggatgctca gccagtagct
    10801 tgagaatcca tactagcgcc gcactggttg tgtgttggcc ggcaatgaga tttccgtatg
    10861 cctagatgca atgacccggt gtcttagtag agatttcaga ggccgaaaga agctgtttac
    10921 ccacctcgtc aatcatgatc tgtttgccat acataggctg ccggtcggcc ttgcgagatg
    10981 acttctgctc tctatacacc atatagtcaa taccagtctt agcctcttcg tcgttgccga
    11041 agcgctgcag tgctaggtta atatgcttgc ggataaagcg atctttgccg acgaagaact
    11101 tccggtaata tggggacatg taccgtgccc accaggacac gatggaggga ggccatttag
    11161 tcgtgtagat ggcagccatc cggtcaccca catcggttaa accctgttgg aatgggtgca
    11221 acgaggcctg aggaaagatg acgtcggtgt gcttcccaac ccctaactga gagttgtcca
    11281 gctgctcgac aaactcaatt tgcctacgca gagccgagtc ctggaagtct tgtccgaagt
    11341 ggaagcgcac gataacatca agagctaggg ttttcaggtc ggccagcata ctgaatggcc
    11401 ttccatttgc tacccgggct ttggattccc aaagatggat aaggttgagc accgaagagt
    11461 ggatgatggg acccacggtc tggtgcagat agtgcggagc tagaaggtct ttcaaccagc
    11521 tgcgggaggt tctccaggag tccccagtct tcatgttaag gtggaactct ccaaataacg
    11581 ggaaccgatc gataatgtaa gacgatcggt cgaagtcact tcgtcccatc agcagctcgc
    11641 gggtctggcc gacgtcagcc acaaggacca ccggcttgga gagcgggccc atcagcgcct
    11701 ggcatatcgg agacccatgc tcctcaagct gcttgctgca ccacttagcc agtccggcag
    11761 gatcgcccct cagagcaggc acgtcgccca aaattgatgt agcggcctgc ttgttgtaag
    11821 gaattcctgg taatgggctc gggagaagcc atcgataaag gacgtataac cccaccaggc
    11881 aaatcgtaat cgagaagaca gcagggtatc catgaaaaag ctcaacaaag ctggcaatgt
    11941 aagaaggcgc cattatgtca tgcgaccgat gaattttgta tttccaatag gatttggaca
    12001 aggtaggcaa tatccaattt accttccgga cggctgttct gagctaaata ttcatggatc
    12061 tttgaggcca agtataggcc cttaatgcta atactaatca tgtcttcgga ataaccaaca
    12121 acgaggccga tgttctttgg ttcatggatc ataaccgtat attcctttcg gccatcatcg
    12181 aaggttagat actgatttgg aaagccccgc ttccttctca gccacgcttg cagtcgagtg
    12241 ccaatgtaag aagggagtga tgtttcgggt ggcgggctgt gttgaaagct cgtccgaaat
    12301 atgtcggccg acgaatatcg gggattatgt cggacgcacc tctacccgtt aattcacccc
    12361 acggaagcga gcaggttcga cctggaatgt agtcagacta cgtgaatatc tccttctcca
    12421 tggttgcgta gacacagtgg ccaccctcca catctacaaa tggcaggtgc aggagttccg
    12481 aatccgttaa tgtaagcact agcagtccat cgaactgtat attccgctaa caactattta
    12541 ctgcttatcg ggttgatgct tcaccggaaa atccaagtga aggaagacct gctacgaatc
    12601 acgaacgcca gccttgaacg ggtgtccata tcctcgccgg cagtgattac aagcctgact
    12661 ctgcttggag gaaaataatt ccactttacg agtggaaatt gccattccaa gacgtgaggt
    12721 ctagagaggg aaattgcagc attgagtatg agtcaccgtg cgctattgtg gataacatgt
    12781 ctggcatcaa ggtcggatcc tctgaagaca tccagagtcc agagccgtct tctaggttga
    12841 ggaagttcga aaggatggct ggagatgaag agctccggct tgactcatta ggtgtatatg
    12901 gctcgaggga atgctccatc ctggcagcct tcgcaaaaag ctgcgtcaca acctgtgccc
    12961 cagaggcagc catttcgctg acctcagcta acatttgaag acgtcccagg gctttctcaa
    13021 ccgcccgcat tgcccggggc cgagtcagag tggccactct taagccgaga atatcgggat
    13081 gatcctcgcc ttgatcaaat ggaaagtctt tctgcgtaca aagtatcaga agaacaacgg
    13141 cggcttcaaa cgtgttgaat atgatggcgc tgaaacgcgt gtgggagcct ccaaacatga
    13201 tatgcagagc tgtgacggca tccagctctt ccagagcggc cagagccagc ttctgcttct
    13261 gcgattggag aagaacttgc ttataagggg gtagactggt gacttggcct ggtttcagca
    13321 acagtaaagg acgaaaattc caacagactg aatcgaatat ggcaatgtag agcagctgtc
    13381 tctgcatggg taatttagga agttggccgt cccacctccg atctggattc agtgcatagg
    13441 ctggtggtag ggtagggata tactctgcgc agaatcgctc ataccgctgt tcgccgtgag
    13501 tagggtcgta cggtaggttc cgtctggaac cgaagcttct ccagaatctg cccagccgga
    13561 cttgcatgag acgctcggtg aagtcttcag gtgcatctgc agacgcagcc aagtcgccaa
    13621 taaacggggc aagacgtaat cggggtaaag tctcaaggac aaggttatca gggagaaaag
    13681 ggacccggtc aagctgtcgg gcgagatggc ttattgatcc ggccacgtca gcgcaaggtt
    13741 gcagtgccaa gagcatggca tacgcacctg tccagaacat acagcccaca taatgtcctc
    13801 cggcgcatct ccttttctaa tacttgagaa ctatcttccc ccggcactgg agccactgtg
    13861 tgaatccccg ccttctgcgc cgcactacaa gcagaggcga tgccttccca aaatttatca
    13921 gtcctccctt cacaagagga tctgaaagcg gcaaataaaa tgtgctggac ccggaccaga
    13981 gaccctttcc agtttagaga cagacaggct ctggcaagct caccaccgag atgactgcag
    14041 gtgtcacgta tgtctgagag tgactgcccc cggatccgat caagggtgtg cgtcggagaa
    14101 ggcaggaatt gcgccgagta ggcaccaatc cgaagtacca gagcggcaaa ctcaatgtca
    14161 tccacagaca ggggccactc cttagtccac caatgctgat actgtgtcag aaagctgggt
    14221 gggtggatga tctgtttcat cctgttccat ggggcatcag ttgaccatga atctaatatg
    14281 atcactaaca agggacctac cagttcaatt catcgacgaa atactgcatc aggaaatcta
    14341 ggatgggacg gggaggaatt ttttccagga cttgtttgac tgtctctagc accgcagttg
    14401 acaggccctg ggtgctttga tctgtgtccc cttcactgtc cagatcccac tatgccgttt
    14461 gagattagcc atatgtcaag aggatggatc cacagttgca tgtgtgcttc tcactttttt
    14521 gagcagagcc atggtattgg agtcactgtg ctcgaagtag ccaaaggatt tagccagagc
    14581 tgagtgtgaa ttagacgcgc tattctgtgc ctcggcaggc gaggccttgg aagatccatt
    14641 tggtaactgg acattgggtg gttcctgggg ctcagggtct ctcgctggct ccaagaggaa
    14701 agtgttggag gggtctccag taatgatgga ctggtagaca cattcctccg gccgtcgacg
    14761 tcgggtgcaa tggttgcacg ggtactggcg gttgcactaa tttttttttt agttcgcatt
    14821 aggactcaag ctttcagctg cccagtgtag gattagcgat gtttacgcac tctctgtttc
    14881 ctagtgtagc agggcacaca ggtggtgacc cgacgctttc ggccggtggg atgcattgcg
    14941 gctcctccca tctggtcgac aactcacaca acaccagcgg gcccgatgcc cttgttatgt
    15001 ctagctgtcg cacaagatta agctattctt cttccagata attatacctt agtggaggga
    15061 tgagggggaa tatctcaatg tgggactgtt tctgtgcctg gaggtcgctt cggggtagtg
    15121 ggggggcgtg tctccaccag catttgggag ggacaagcca gacagacaca gaagaccaga
    15181 taggcagact gtcagaccgt cagacatttg gggtcagacg gccagacggt ccgtgagcct
    15241 gcatggattt aacttcagtc cggataagat cggccacgcg gaacggaaga acccgccgga
    15301 tctacttggt tatgcttact cggtttactc ggcttcaaac tctcatcaac aggaaacgtg
    15361 cggctctctg gctgtttctg atggtgttat tggtggccta aatcccgtgc atcccaatta
    15421 cactgaaact aaccctcctg atttgttccc atggcacccg ggccatcccg gagctgtgcc
    15481 taatatgctt gatctatcac gtcctgtgaa gtacgttcaa cgtagactag actccagcag
    15541 aacctgtaag atcagacaag ctgcatctgc aaccttcaat gaattcgttg accagcagga
    15601 tcgccacgct tatctcaaca acacccactt ggagccgctc attgtactgc atatcacatt
    15661 tttgtactac gtaccgtcag tggtccgtgc gagtgggttg gagcatgggg aggatttgat
    15721 cttcgtcaga gggccgttaa ccccataatt atcaacagtc tggtttcatc ccatctcggc
    15781 accttttacc ttcccaatat ggcatgcttc tcagtccggc ttgcttggga tcccctcaat
    15841 ctggggggaa aggaaggtgg ggaaggatga agggggccaa aaaggacctc tgaggaagag
    15901 gtctagtctt aggcgcccgg gactgtggct gaaggtaggc aatccttcca tttattgcca
    15961 atgacagaag ccagcaaact tcggctcgca acagagaagg aatcgaatcc atgcgaagtg
    16021 tctcgcttct gagtagtgct gacgaaagtc acggccccga catccatcgg tcgcatcggg
    16081 cgatttcgcc cgtccctcct ccgtccagct tatcacgatc agcatcaaca cgagccgcca
    16141 agaaaaggaa tctgaggact tgtctgttcc tccaacgtct tcggccgagg tccgtagaca
    16201 gcacacggcg tcttcatcaa ctggaatacc cgaatgtgaa ggctgccacg aaacggccga
    16261 cgcggggctt aatgagtgca gtagcttcat gcacgtatgg tgaacatggc agcagataca
    16321 ccatcagaaa gaagacaact acagctattc accgtagata gtgcaggagt caggattcaa
    16381 gaacaggatg aattgctata tagggcctgt gttgccatgg acgagacagt tcatttggca
    16441 aatacagcaa cttctctatt gaattcgaca aaaagcacga acgatctcta tacttcatct
    16501 ttaccactct catacccata ttccttactg agccatcatg acacccccaa gatcaaatga
    16561 gtgcgagcca attgccattg ttggcatggg tgagttgatt atatcgggct ttggagagaa
    16621 atcaagcatt gttaacatga ataggctgtc gcctaccggg aggtgttcag gacattcctg
    16681 cgttgtggga gttcctccgg gaccagaagg atgctcacgg ggagtttgcc gcgccgcgtt
    16741 tttcagccga aggcttctat catgccaatt cagaccggcc tgggactgct gtagccagca
    16801 gtggcttcct cttgaaagag gacccgcggc tttttgaccc gtctttcttc ggaattaccg
    16861 atgtcgaagc ggaaaccatg gacgcctcgc aacgcaagct actcgaagtg acgtatgaag
    16921 catttgagaa tgcaggggag acatgggaca gtgtgtccgg tagccgaatc ggcgttttcg
    16981 tcggcgatat ctcgttcgac aattatgtgt cccagacgcg tgattgggac tatagcggca
    17041 aatactcggc tactggagcc tttcccaaca tgctggccaa ccgcatccac tacgttttca
    17101 acctcaaagg tccgagtctg ctaatcaaca gtgcatgcac ctcggccatg tatgcgctcc
    17161 acctggctat tacctctatg cgcaatgggg attgcgattc ggccatcgta gccggatcca
    17221 actgggttat ggaccccaac tgccacattg ctatgggcaa gctgggagcc ctgtcacctt
    17281 cttccagaag ccacactttc gatgcctccg cagacgggta cgcccgcggc gaaggtttcg
    17341 cagcactcta cctaaagaca gtctcgcttg caacccaaga tgcgtctccg attcgcgccc
    17401 taatcagagg cagtgcggtc aacgccaacg ggcgtacgag tggtatcacc aacccgagtg
    17461 gccccgcaca agagactgtc attcgagaag cgtgagctct atccatgtta cacactttgc
    17521 acctcacgca tgaccttcta atactgactt gaacagctac aagaacgcag gggatctcga
    17581 tccctccgaa acaacccttc tcgagtgcca cggaacaggc acccgcgttg gggacccaat
    17641 tgaggtgacg gcagctggga atgtgtttgg gccatcacgg tctactgtcc atgaagatcg
    17701 cctggttgtc ggatctgtta aaactaacgt gggccatctg gaaggtgcgt gcgccttgcc
    17761 aggtatcctt aaggtggtcg cttctctcga ggccggagag atccccgcga cgctcggttt
    17821 ccagaccccc aatccacgca tcgactttga ccaggccaag gctcgcgtcg tcaataagac
    17881 agagccctgg cctaaagacc gacttaagcg tgccagtgtt acttcggcag gctttggagg
    17941 gaccaacgga cattgcatca tcgaccacgt ccacaatgtc atcccggagt atgtgaagcc
    18001 tggcgtcatt tacgagcaag ttgagcagtc caatggtaca aacgggcatg ctgttaatgg
    18061 taccaatggc actaatggca cccacggcac caagccagaa gcactctccc agctgcaccg
    18121 tcctatactc cattctccga ccctcgttag acgggccgat gccaccactc gccagatggt
    18181 ggttctcccc ttctccgcgc acaaccagtc ttctctgatt gcgaacatgg aggcgctgca
    18241 acgatccatt cctcatcact cattagccga cgtggcctac actctcgcag ctaaacgctc
    18301 tcgattctcg caacgagcct tctcgattgt tgacaaggac caggtcaccc aggtcggatc
    18361 ggtcaccgac aacggaccaa aggtgttcgc ctcgcctcaa cgggtaaacg tcggttttgt
    18421 cttcacgggt cagggtgctc aatggccagc catgggggcg gagctgtttg agtacgctgt
    18481 gttccgagat acaatcgcat acctcgacac cgtgctggct gtgttgcccc agcccgctcc
    18541 atggaagctt gtagacattc tgtgtgggaa ctgtgacaag gatctcatcc agaagcctgc
    18601 cgtgtctcaa actgtatgca ccgcgctaca gatgggtctt gttgacctgc tagcatcatg
    18661 gtctgtccgc ccggctggcg tcgtgggtca ttcatcgggc gaaatggccg cagcgtatgc
    18721 cgccggtcgg atcacagccg cagaggccat caccattgct tactaccgtg gatacatggt
    18781 ctcattcaac cagaaaaagg gtgctatgtt ggctgtcggg cttggagcag accagggtgc
    18841 cgagtatgtc cggcaggccg gtatggaggg aagagtcaag gtcgcggcga tcaactctcc
    18901 ggcgagcatc accatgtctg gtgacgctga tgccattgag cagctgagcg tccagctcac
    18961 ccaagaagct atctttaacc gacagcttcg caccggagga cttgcctacc attcacacca
    19021 catgctgtca tttggtcacg attacgctca ggcagttgat gatgggttac agcgtcttgc
    19081 cagcctagga atcaatgaca ccacttccag gtactccaac attccttggg cttcttcagt
    19141 ggtgccacaa aaaagctcaa ccatgcctcg cgaggaagtg actgcttcat actggaaagc
    19201 aaatctggag tcacccgtac ggtttaccga tgccgtatcc aagctcctcg acatggatga
    19261 cctgagaatc ggcgcaacgg tggagatcgg cccacaccca gcgctgaaag gcccattggg
    19321 gcagatagtc aaaggtctgg gacgtacgat tccccacgtt gcctcggtag agagaggcca
    19381 ggattctcgc cgctcgctac ttggactcgc cggaacgcta tttgccctga atgccgacgt
    19441 cgatttggtg gcagtcaacg ccgtcgatga gtcgcatggt gcgggaaaaa gaacgctcat
    19501 acatggatgc atggctattg acctgccgcc ctaccggtac acctatgggc ctatcaagta
    19561 ccacgagagc cgtctaagca aggagtaccg actccggcgc tggccccggc atgatctgct
    19621 tggagcccgt gtgccaggga caactcgact gcgtccgcaa tggcgaaaca tactccgctt
    19681 gaaggatctg ccatggctta atgaccatcg cgtgcctcct cacgttctgc atcccggagc
    19741 ggcgcatatt gtgatggcca tgctcgcagc agagcaagcc tatgcggaat tccccgatgc
    19801 gttacctgtt gctggcttga ctctccggaa cgtctcgatc aagaagaccc tggttgtccc
    19861 gcaagatgac aaggggattg agatcgtgct cagcatggag ctcgaggatg gtgccaccgc
    19921 cgcatctcct ggatgggcaa gcttttccat cgcttcggtc gttaacgact ccgagcagtg
    19981 gacggaacac tgctcaggtc tagtcaaggt tgatgtcgtt gcctttaacg cgcctgcggc
    20041 cattgataca actaccatgg atggacgcgc tgtagatgcg caggcctggt acactcgctt
    20101 tgctgacatg ggactccagt ttgggccctc gttccaaggg tattccgata tctgggctga
    20161 cccgttcagc aacgtggcat tggccaagct atcgctaaac accactgcag gattgttccc
    20221 tggaggcgag tccaggtatc ccatccaccc cgcctccttg gatcttgtta tccgcctggg
    20281 actcatggca tgtaatggcg gccaggcaga aacggccagt gtccagctgc ctatccattt
    20341 cgatcagatg cggttcaaac ttggctgcct ccaaggccgt gactggatca caggggtatc
    20401 gcgcggcgag ctacgtgggt tgcgtggagc gtacgcccaa ctgcaactgt tggatgactc
    20461 cggcgaggct atcttggacg tggacaacat gcgtttcacc agcctgaaca atgagcagca
    20521 gtcctctgca caggattttt ctggccaagc ttattccagt cctttcgcgc gtcttgtctg
    20581 gaggcctgat agtcgcacat tgagtcggga tcagtggaac aaacttcttg cgtctgtgga
    20641 cgggaccacg actttctctc ggctctccta cctcatcgac ctcgtaggcc atgccaaccc
    20701 agatcttcga atcctgcagc ttagcgctgg cagcgatgac cggaatgctg gtcaagcagt
    20761 gctaaagtcc cttgtcggcc acaatggcat caagcgctac cgggaatacg tcgcaacgga
    20821 cacctctgcc gagcgactgg actccttccg tgagactgtc tcagctttcc gcgacgtcag
    20881 atactccgtg ctggatatca gccaagatcc ctcggaacag gaattccaaa tagggaccta
    20941 cgacatgatc ctctggagca atgtggaaca tggcccggct actgagcagg ccctggcaaa
    21001 cgccaagaag ctcctccatc ccgggggcca ccttgtacta gtggaccgca tgaatagcag
    21061 cgaactggca tgggaccaat gccttcggcg agttggattc gactcaggat ataagctagt
    21121 ctgtcgcgaa actgatctgc actccaccat catcctatcc accctgcccg atccggtacc
    21181 aactaccaag agcggcaacc ctgtggtcca ccttctacac gggtctcaag gcacttcagc
    21241 gcttctccat catctcgccc gggctatgga acagcacggc ctatctatcc ggatcagtcc
    21301 tatggaccaa gcaataaacg tactcgctcc caattctcgc gtggtggctt tccttgacgg
    21361 agaaaacctt ctgtttgccg ccgatcaacg ccgactggga ctattccaac atctagctgc
    21421 aaacacggcg agcatggttt gggttacctc gtgcggccta gtgaagggcc gaaatcccga
    21481 cggcgcattt gttagcgggc ttctacgtac cttgggaact gagaatcccg cagggcagtt
    21541 cttgtcagtc gacgttgatg cggaagactt tcaggttcct ggcctggaga tggacgagct
    21601 ggtccgctgc ttggtcgaac aggagctcct cctgcagccc accctcgatg ataaaggacc
    21661 tcccgaggtg aatcgggacc tggtttggca agacggctgc atgtggacga gccggatcgt
    21721 gcctgatggg cagctgcagg gatacgcgga ggtggctccc accaggcagg aagttgacgt
    21781 gtcctcacgg ccactgagca gccttggacc cgtacgagcg gcctttgaga cacctggtat
    21841 tctcacctcc ctctatttcc gtccgtatac agagctgttg caacccctgc ctcgggatta
    21901 tatcgacgtc aaggtggatg ctgtcgggct caactggaaa gacctggggc tgtgttccgg
    21961 tcgatttgat gcgaacaacc tctccaacga atactgcggt gttgttaccc aggtaggagc
    22021 tgatgttact agattatcta ttggcgaccg ggtttatgga atgggcaagg gacactttgg
    22081 cacgcacact cgtgtgcccg caggtctggc acagaagctg gccgcggacg tcaacgccat
    22141 cgaggcggct actatgccgc tggtgtatat gactgcagtt tatgccttcg agcatgttac
    22201 tcgcctcaag cctggccaca aggtactgat ccaatcggct acaggcggcc ttggtctggc
    22261 agccatccag ctggcgcggt ccaagggggc caccatctac gcgacggcag gcactgcaga
    22321 caaagtccgt ttcctgacag accacatggg tgttccagca tcgcagatct tctcgtcccg
    22381 cgacttggcc agtctgaacc gcgccactca gcaacatgga gggtttgatg tcatccttag
    22441 caccgcccag ggcgatatgt tgtacgagtc cgtcaaagcc ctcgccccct tgggtcattt
    22501 agtcgacgtg ggtcgcctgg atgtcactag ttcccaaacc atgggcctgg aacttttcca
    22561 aaagagtgct gggtttacct cctttgacct tggcctcgtt gtggaacgcg actctgtcct
    22621 cggggcggag ctgatgcagt ccgtcgacgc gcacttccgc gctggccaca tcggacccat
    22681 taagccctat tccgttgcgg acattggcta cctggaccaa actctcttgc agttctcgca
    22741 aggcacccat attggaaagc gtgtcattac ctaccaagac ccgtccacct tgctgcgcac
    22801 tctccccacc tcatccgcaa ccccggcgcg cttcgaccca gccgcccgct acatcctcgt
    22861 cggcgggctg accggcctcg gccgctccat cgtgcggtgg atgagcagcc gtggtgctcg
    22921 cgacatggag gtttggtccc gccggggggc aagcaacctt gcccccgaag cacagcgtat
    22981 gatcactgag ctggcagccc aaggcatccg agtccagccc gttgcctgcg acgtaaccaa
    23041 ccgtgacgcc gtgctccaca ccatgcgatc tgcgcatgtt gatcccacac gacctgttcg
    23101 tggtgtcttc cactttgccg tatcctacca ggatatctcc tttgacaaga tgaccgaagc
    23161 ccaattcaac caaggcatgg cggccaaggt cttcggcgtc aagcacctcc acgatgccac
    23221 gacctccatc cctctcgact tcttcgctat gacctcctcc ttgggaactg tctatgcctt
    23281 ccctacccag agcacctatc tcgctgccaa caactacctt gactactttg cccgctaccg
    23341 ccgccggctc ggtctccctg ccacgaccgt cgccctaggc ttcatcaacg acctgggccc
    23401 gctaaccaat gaccccgtca ccgtcaacct cttcgtccgc gccaaaggcc aaaccatgac
    23461 gggagctcag gtcgtgcgca tgctcgagcc agcctttgtg aatgagcaac ccaatgccct
    23521 ctggctcggc cataccgatg accccctctc cgcatcccac atagtcactg gcatcgaccc
    23581 agccgtcctc gccaagatgg cccggtcatc agctgcctcc ctcgcctctt ctaccattcc
    23641 cagatggtac cacgactctc gtgtctcctt aatgttgcgt gccctagaag acgcctcgtc
    23701 cgctacctct tctctcagta gctcggacat ccatgcctca gacgcatcac ctactgccca
    23761 actgagacga caattcgacc actccgttgc gacgctccgt gcgggaggta aagattccaa
    23821 ggaggatgca tggacggaga ccatcaaatt cgtgactgag gccatccagg ccaccgtggc
    23881 aggcatgttg tttgtggatg tgggaagcgt gaatcccaac aagacggtgg cggagcatgg
    23941 cattgatagt ttgctggcgg cggagtttcg caattggttc cagggggcgt ttgggagggg
    24001 ggtgagtatg ttggagttga tggatgcgag gatgagtcta gcgttgttgg cgaggtcggt
    24061 agttgagggg gcggtgggtg tgtgatattt acccacattg agtactactc ttcttagtac
    24121 tctatagact gatatcataa aggaagtagt ttatttacac cctcatcttg ctaatgtcca
    24181 ttacatatta tcccaacaag tatacagacg acattcatct actaacaacc tccataccta
    24241 cccccaaacc ctctgataat ctaccacccc caacatgatc cactgcccac tgaatatacc
    24301 cccgatacct gccatccaaa tgccactgaa tcccctcgag aatatgccgc ggccacccac
    24361 aaataaacca aacatgatcc agccgatcaa gcggatacaa aaagaacgca aacagaatca
    24421 acgccaccgg ctccctccgc tgcaaatcac ccaccactgc gtccggcaac tgatacaacc
    24481 acgcaaagac aagcgggaag agagccattc ccattgtacc ctgcggatcg ggacccatga
    24541 tggcgtcgag gctgtggcct agtcggtcta gtgtttgcag atagattgag agccgtgggt
    24601 cgtcgatggg gatggttgtg gtaaggaggg cgcggtaagt ttctaggtgg tgcgggtaat
    24661 cttctaactt ggttttgttt tgtgatgcga tatgggagtt ttcatgttcg gtttgaggtg
    24721 tggtgcgaga agaagaatca tcgccctctc catggatgga gaaaacgctc gttggcatat
    24781 ctccgctaca tagctcgaat acagaccgca caccgaggaa caaagacaag tggcctgggg
    24841 tgccatcgct ccggaacgcg aggtactccc ccggttgagg gccacgggcg agacttgaga
    24901 tgaagatgaa tattgcggag gcatacatcg cgggactgtt gtcgcggtca aggtgcggta
    24961 aggtggctga gacatctcga atagcaacgt taaagtggcg ttcggcttca gtgtatattt
    25021 ctgcttctgt gaaacccatg gattgggacc attgctgatc gtctgatcgt cgcacgaggt
    25081 ggaagccgga gaaggcgagg aggatgtgca tgacgtagtg gtgggaaaaa gcgatttgag
    25141 ataattgctg acgggctttt ggttgggcgc cggttagttc aggggaagtg gagaagtggt
    25201 gaaagaggag catgtccagg gctgtgtatt ggaaggggcg cttggctagg tcgttgtttg
    25261 atgggggtga tggttgggtt gtgtctggtc ctgatgtgag aggtgtgcca tggcctcgtt
    25321 ttgggggttg aaagttgacg gatgaggatg tgtagaaggt gtagctatct gtgctggggc
    25381 cctgtgaggg tggtgatacc gagtctgatt gctgtgattg tggagaggag ctggagttag
    25441 tttggggttt gaaactgtag tcgcactcta ttgaatggcg gaggcagttg gtgcagtgtg
    25501 gcttgatctc atcgcactgg ggatcggtta gtatctctca ctcattgaag cgcccagagt
    25561 ggagaaggcg tcgggaactg actttaattc tacgcctctt acagttctta catcccagac
    25621 gggatttgcg atggcttttc cgcgatagcg tttgggtgta tggagtgagg gaagcgccca
    25681 ttatctcaca gtacaggtgc tttgattaag gtggatgagg tggagtttgg tcactggcac
    25741 gcctggaagg ctagataact agttgaggaa tgcggcgtag acaccagcgg catgcttaaa
    25801 ttttaaacag agcgaataac gttggttcca gaagggcttc agggggcgtt ggcccactcc
    25861 actgcctttg cagcctgccc ggggaaattc cggttttacg tcggtggatt ctcggcaaca
    25921 actcgtccag taattgtggg ttctgtttcc tcttgctaca tgcatatctc cattccatgc
    25981 ctggtatctg catagccatt gttttctccc ttcatgatct gtacatttgt atagcgaata
    26041 aaaaggtctc tgtgatggat accgactgcg ggctttatat tcccatctcc tctcgacgcc
    26101 ttttaacctc cattttcaga ctcgggtcaa ctgccatact aaacccacca tagcgaatct
    26161 ttggtaccgt cccttccaat agcttccagt cgtaccgcag taggagatag atcaaggcaa
    26221 tcttaacctc attggcggcg aagaagcgtc ccggacaagc atgtttgcca tgtccaaaag
    26281 ccaaattttc cggagccgtt gtgaccagct gcgccttggt ctgtcgctca gggtcttcgc
    26341 gcatcttgta gaaccggtac ccgtcccagg cagctgcatt ttcgtaggtg tcatcatccc
    26401 agagcttgtg ggccgatacc gcaagcatgc cattcttggg gatgaccgtc ccgtcggaga
    26461 gcttcacttc cttgagagct acccggcgca ttgaggctgt tgacaattta tttagccaaa
    26521 ccagtggaag gtatcaaaac agatgggttt atgctctgct caccgttgtt gattggtttc
    26581 agcctttggc tctcccggat aacactatcc agcagtttca tgttatacag agcggtcttt
    26641 ttccaaccat gctgttggag agtgtcaaca atttccttgc gtaaaggctc caaaatctcc
    26701 ggattttgca cgagatgggt cattgtctga gatgtcaggt cggaagttgt gtggatggcc
    26761 gccacggaaa ggataagctg cgcgctgaca gggtcatagg gacgaccttt ggcggccttc
    26821 tcaaaccatt cgatagcatc atcgaaccct tgtgattgtt taccctctgc atgaaggtgt
    26881 ttcttaaatt gacgcctctc ctctagtatt ggtcccatga ctttcctagc tactttcacc
    26941 tgggccctaa gcttacggca tcggggcaag aaccagtgta cgatgggtcg aatagctgca
    27001 ggccacatgc gaagctcttc cgccgctaag aatccatcag tagtatagtc ttgagtgact
    27061 cgcagccatt cttcattccg gcacaacttt tccccaagga agacacggga ggaaatgcgg
    27121 gaaataagag ccaccatcac agttctcaac tggatcgtgt gccattctaa tcatgacaca
    27181 cattagcatt cctatcgtcg aattggaaag tatgagattg tctaccttca ttatctgtca
    27241 acagttcacg gacggcgaca gatgtctcgt tggcaagggg ctcggtgacc ttgtctgcca
    27301 agatgccgaa ttgtgagtta gtatacagtc atgccaccag tgccgtgaag tccgataact
    27361 aactcgggta ttttgtcaag tcgtttccga taacagcctg gacaatcccc gagtcttgac
    27421 taccttcgcg gaatccgtca aatccaggta gattgccatg aaatgcctgg catcttgtca
    27481 gctactttca cacgagctcc ggatcaaaca taaaacacat gaaagtcgga acacacttcg
    27541 aatgtccagc gagagaagct caggcggtcg tcattcctga tctcattcgc catactcgga
    27601 gggagaattg tcactttccc agtgtcggta tgcaagagca ctggcgtatt tgaatgagtt
    27661 gtaaaccaat cccatagcag tcttcgcgca ttggagaagt attcttgctt tactctagta
    27721 gacgtgagct cgaagggctt ctttggattc agggccgggt ccttgtatct gaagctttga
    27781 agtaggagaa acgcgaggcc taaagccagc gatacaagga cgggtactgg catcgaggta
    27841 taacccagca tgttctccat gcttgcacgc aagggcctaa aaggggtgtc tgtaaagaac
    27901 ataacgtagt agtgctaaca aaaaagatga gatagggtag cggcatcaat tccaacaacg
    27961 gatgaggata gacgcctatc gatacttact taaatacttc caaattgtga ggggctttag
    28021 gcgttgagat ggccaggatg tagttgaaac aatgcctcgt tagtatgccg catttcccgc
    28081 ttgatctgca agaagcgccg tcagggtgga accccactga ttcagcggtt atgcattgca
    28141 tacgggcata gcaggaagtg tctcgtcatc cattaggatc attcatcatt taccatgaat
    28201 aagagagttt gtgcactggc attgaacgca ttgatgcgcc agtatgtttg atctgtcggt
    28261 ctcgactcca atgcaggaca ttatttatcc gagacataat actcgtagta gacgatgcat
    28321 cgaataatcg atatgcctct gaagtggtaa gcacaggatg aaagcaactg ctaagtttag
    28381 gtgaaatttc catccctaag atagtgttgt tcacaaggaa caagactcgc aatatgaacc
    28441 acaaccacac ataattgaac agaagctgtt actcctgtgg atagctgcat tgagttactc
    28501 tacctgagtt gcggggaatg tcaaatcagc cctaactgat tggccgcgtg tttttggttc
    28561 cttgtccagc ccacgcagag tcgtcatcac tatccacttc caatcgaaaa cgactgagcc
    28621 caaccacaag agaatatcag tatgcttcgg ttcaaatcgt cccttctgca taagatatac
    28681 gcgtagacgt ttgaactagt ctaaatctgg tataggcttc atgcatgaat tgtccccacg
    28741 taaacttcct atcccgagga cataagcaat gattcagcgc ttccgagacg cctgcagtcg
    28801 gtgcatcagc ccactcattg ctgggaagcc accttgtctg ttaaccgcat gactggcttg
    28861 gtataaatcc tttgactttc atttgaaggt atcaggttga cgtcaaggat catttaacct
    28921 agtgcccggt tttggatttg acacctttca gatccaagca aacttgacat ttgggtaagt
    28981 ttcattggcc aaagaacagc ccattccatc tcagtccatc tgactttgtt agccagatga
    29041 tatgtaacat catgcttggc gatgaaagag tcatacgggt gttttggtcg aaaagctcgt
    29101 ctccaccgtc atccaccgaa gtttggacaa aatgattcac gtcgttctat attgccgagc
    29161 taacacattt gtcccagttc ttggtgtcta ttttgtctta gcgcacctta agtgggtttt
    29221 ctattgtttc tgatgcccca gtcctatcgg gataccatag ggaccccaaa gtacatacaa
    29281 gatctactaa gtatacagta cattagagca ggcggtattt actgcgaagg attgaaacag
    29341 agtatcctag tttcagttta gagaccgtgc actcagcgac acaatagaac atggttttct
    29401 atgtgcaagt gttagttgtt tctggacaca ccctcctcgt ttacttgcaa tcatctacaa
    29461 atcatgtccc gagtggagag cacaataaat ccatatcatt ctataaacat caatgggact
    29521 cgtctctcta tcaaccactc cgcctcaact atccatccat gccactgttc ttctattcgt
    29581 actatattct tacccccgcc cccctttccc caacactaat ccctgcacaa ttctactccc
    29641 gcttcgtctc tcctgcagca ggcccaagca acctcgcaac agtcggcagc ggccacgcga
    29701 gctgtgcaac cgagtcccgt tgcacttccc cggaagtaat caaatcaatg accgccacgg
    29761 cgatatatcc accaatggca gtgaagacat gccaccttgt atgacttgtt agccaagttc
    29821 aagtttatcc cggaccatgg ggaaagatct acataccagc catgcagctc aagcaagaac
    29881 gccacgggta gcccgaccgc gtgtctggct acgatcaagg attgacacac aaactcgtca
    29941 atcagccaga cgagatatcc gaagatgaag cttgctgcat acatgttaga attaactaca
    30001 ttctcatctc attcacctag taggtaagcc aataataaga gtgtagataa cataccacat
    30061 ccaaacagcg ccacggactg aatcctttta cgggcctcaa cgtccgggat ctcgcgagga
    30121 atgatcttga gcgtgcgagt cgtgatcaga cacactgcgg ccccgaatgt cacggcgtga
    30181 agcaggaact catccatgac catgtggacg accatgacga tcgtgaacag tacagagaga
    30241 atgattccta ctgtctttgt gtactgaggg gtggcctgga aagatagaat gcggtagagg
    30301 agtggtgtag tcaagaggtg catggaaagt tcatccgctg ttgagacgga tcagctcaga
    30361 tcacgataat tatcattccg agtaagctga agaatagagg gaggcagtac acatctgggt
    30421 gtgatatttc agagtcatat ggtaaccggc agagcaaaca ccgacgccaa tcaatccgca
    30481 gtatgtgatt gagcgtggcc cggtttggcg tctgctgtgg agctgccaga gaccgtagat
    30541 gccatataga actagagaag agtgttaatt tgtggactac tgtaaggggg gaataaacgc
    30601 actatagaca aagctgctaa gagtattaat aaactccgca acatatcgcg taattacata
    30661 gtcctagagg acaaatcagc gattattgtt gtgggccaag aaaagaccag attgcgcttg
    30721 ctgtagacgg acctcttcac agaagctgtc gacattggtt agtctccgac gtatacttca
    30781 attggctatt aattaattga catacttcaa ataagaggtc ggggcacccc agaaaggcga
    30841 aatcgcggaa gccattgtcg cgagcgttcc tggcgatcaa tatgggggag ttgggaatga
    30901 gaaagaatgg ggagattggc agacgggctg gaataataat aaatcggctc cttcgggaac
    30961 tccaccgcga cggtgaccca ctcgtgtctc ccgtgcttag caggccttgt tcctgcacgg
    31021 tttccggggt tgaagacaat tacagttttg catacgggat gatgtagcca attttgaacc
    31081 tatatcccca cttgatcccg tcaaccaagt gcctaagagg gtgaagtcat tacaggcacc
    31141 tggaatacat tttggaccgc ctgatgggct tacccgaccg ttccggacgg ggctggctcg
    31201 gcttctatcc ccagtcttgg cattggcgtt gaacaaggta tgaatctcct ggacaatttc
    31261 aaagttgctc aaaaacgatg ttttgcttgt ataaactaag ccaatttagt ctcaaaggcg
    31321 atactcgctc tcttcaaagt tcaattctgc gatgcaggta ttagccccta gcatatccga
    31381 cttgccctgt ggatataata gtttgctgcc tgaggcctcg caatctacac aaacaacgcg
    31441 tcaacacctc cttcttgcga atggttcaac agaattcgag gctcctcaac ggctagtccg
    31501 cgtttgaaag gttcctacgt ttataatatt gcgtctctca agaaaagacc ccgattcccc
    31561 atcatttcgc atatttataa gtagccacaa aacttagatg taggatatga tggtcacata
    31621 acactcaccc atgcagctga atgtcgtcac atgtgtaaca actatttccc tcaatatttc
    31681 cacactccac agatttaaac ccactcatac cacggcaaac catctcgaag aacctcataa
    31741 tctgtccctg agtcaaattg cgggccctcc gcatctagga aatatccacg cgcacactcg
    31801 ttaaactgga cccgcgtcgt ctgctccacc tcatagaaat gatcgtagtg cacatccaac
    31861 gcgtctttca acgtcataac ctccccacgc ggatgcaagg cgtcccatgg cttgacgcat
    31921 acttgggcct tgcaggactt gagcacgaga agaagggagt cgagtcgctg aacgactttg
    31981 gaaagatcaa cgtttaagat ggtgtgagag gtcgcactgg gttgttcaat tgcggaaagg
    32041 agattatgaa gttgatgagg gtcagtctgt ctctttggtc agatttccca agagaaatgg
    32101 gtttgggagg ggccaataca gtcatatcat agagttcatg ctcattgtta caccaaacgg
    32161 aatagtaaag attatatcca attcccttga tgcggagggc tttgtatgtg ttgttgtatg
    32221 ccgataggtc aactttcatt atcaagatta gctcagccat ggtcaaagag tggggtgtag
    32281 gagtagagta cgcacagtcg tatataccct cgcccgccgc atatctccaa tattcaaccg
    32341 tgacatgttc ctgtctctct tcttgggccc tctcgatctg gctcctcgtc aacgaaatag
    32401 ggttgccatc gaagtcctct cgaaggggaa tacccagcag ctcgagaaaa gtgggagcaa
    32461 gatccgtatg cgtggtgaca atatccgtag atacattctg cgcgatatcg ggaccacgaa
    32521 taatcaaagg aacattgatg tcttcctcgt atccacacga cttgcctggc tgaagtcggt
    32581 gttgaccaat gtggtatcca ttgtcactac tatagactat atatgtattg tcaaggatat
    32641 tgtattcctt caaacgtgta aataagccat caaccagctc gtcaacggcc tggagggtgc
    32701 gtagacgctg gcggtaaaaa tgatcgttgt agtcaacatt agtatcgttt tgtcgcttga
    32761 gagtcttaat ccagttggcg cctgaaggga tttccggatt gaaggagggg gtgcggggaa
    32821 ctttgacatc tgggaatagg tgctcgtgtc gcttcgcggg gataggtgcg ctgaagctga
    32881 atttagggtt ggcgtctaag ccagttccat tcatgaaaac gttgcaatgc ggtgcaattg
    32941 gagcaaccgt gagaaagaag ggcttttggg ccgtgactgc ttcgttgagg aggcgatatg
    33001 ccttttgtgc gaggacatca gtgctgtatt cgccttcgta gctttggggt atttcgtggt
    33061 ctcgttggaa ggtactgtta aggtagtcgt atgtgaatgg atcgaggagg aagtcctaca
    33121 tgacagatta gagtgccgac tgaatagaaa gtctgctgga tgactcacgt tgccggtgaa
    33181 cccagctggg aagggggcgt tgtagttgtc gaccgtgtgg acgttgaaca gtttaccagt
    33241 gtagtaggtg ttgtaccccg cttcctgcag ccaaacaggg agataattgt catttagacc
    33301 ttgagagatg aattttggat agccgcctga aagcgtatga gaatatcccc cgatataagt
    33361 gacgatgtgt agtacactca ccatgcggag gattgacatc cgtgacgttc gtattgtggg
    33421 ccagctttcc cgtccaaagg gtcacacgcg atggacaaca gacactggtt gtacagtaat
    33481 gactgcgata gtgtgttcct ttgtctagga ggtgcttttg tacataaggc atgtaatcca
    33541 aagaggcgag atgggcgtct tgatcatcgg ttaatatgaa gacgacgttg ggcttggcgg
    33601 tcgcagaaag cggctgttgc tgcttctgct gccctagcga tttcgtagta agcccagcca
    33661 gggctaacag atacaccaga cttcgcatat tgctagtata gtatgagttt gcgggcttca
    33721 atttcaaagc agatgaacgg ctgacgcagt gaggttcaag gtaattgctt aataaccccg
    33781 cgcataacgc aatctgggtc aaagcgggcc aaacacaact agttaccttg caggatgccc
    33841 agagcatgaa agtgtgatat agagaatatt ctttcaagac attgttatta tctgaccgcg
    33901 tgctgaagca cgatcgtcat acctcatgcc aatgaaaact ttcgtcaaca cttcatttaa
    33961 gcatttcgga tagtgcttga cttagtactt acttagtact agcaagtcgt ggcggatgta
    34021 tcgaggttga gaaaaatata tcatggatga tctggcaaaa taaatggcag ccctgcactg
    34081 cggactattg cccgcgacaa ctgcacaatt cctaacgtgt cagaaaaatg gaacaacagg
    34141 aatggaatca ttgttatggc tcgattgaaa gagataatga ttagaataca aaagtagcga
    34201 gtacattact gcggaatgag tacttacaag tactactatg tgggcgtcac cgcagcgacc
    34261 attttctgcc gcgctctgaa gggcggacag gattagcttt gtctgccacg gctccatttg
    34321 cggacgatgg gccactgcgg ggcgtcttca gattcattca agcggccagt ttcaacaact
    34381 cggtcccata gctcagttgg ttagagcgtg acgctaataa cgtcaaagtc gagggttcga
    34441 gcccctctgg gaccatctct tttttgcttt tgactattct tcacatcttt ttgctccagc
    34501 aagcttttgc cgctggcaaa tcaaatgaca tgctcgttgg ttggcattgg ttggtgctga
    34561 ctaaaagcca aatactccct ttgtcagtgt catttttttt tgtttactat cacagtaaaa
    34621 cacctataca agcaaccact gatatagggc atcctccact taaagtaacg ttaaaaatat
    34681 gtgcggctag cctggaggag caagctggaa agggccactt aaggagccgt cttcattgtg
    34741 atgtttcctt tggttttagc aagcccgagt acaggttttg ttcatgacgc aaaactagcg
    34801 agagcctggc aatcttaatc tggtactgcg cgtatgtttg ttggcgcaag ctttcaagga
    34861 agtctggaca cgtcctcaac aaagcagatg gaatggagta aggttagtga atggttccat
    34921 ttgcatgctg ccggagaagc tcttgacggt tcgtgggatg ataggcagga tacaacatat
    34981 tctaaggaaa cagtcaggaa ggtgtccaga tggactttat cagggcattt aaacacccct
    35041 tggatacgca aatgctccag atcttcaggc agaatatgtc ttagctgcag aaaattaaaa
    35101 gaaatcgggc tggtgctcct ttgccgagaa ggaggtcccg gataatacag atttagtcgg
    35161 gccttactca aatcgcccag taccatagcc aaaggaaagg attctccaag gtaaaaaaaa
    35221 tccagtattc atcaattaca ttccgtacta tctttgtggc tattcaggaa gtggtcgaac
    35281 atggcagaac aggagatacc tctataaaat atagtaatat ttatccaagc ctccagaggg
    35341 ctgttagaac ggtgaatcgg caagtccagc actattcagc ggaagagaat aatccctgat
    35401 tgacattggt taacacagta agtatagtgc atttccaaaa ctgaggattt gacgctgctg
    35461 cagtagttgt ctggtgggat atgggagtct ggacgggggc gacagtagcg gcgtgttgca
    35521 tgaagtgacc gtggtggtcg acattgcgag gacgtagctt tcgggtatat gtgccccgcc
    35581 tgatcttgcg gggactgcaa taaatttatc actctaagcg caatttataa agggaattcg
    35641 atgctgagca tcacatctga tgcgcttcta gttacatcac ctacatgcct tgcccgctca
    35701 aactcgcggc tgagctggct ttctcgtata attctgcgct ttgggcattc gtggaagagt
    35761 ttcggtaaag ttgcgaccgt agactctcaa gtgtccatca gtcttcgcag gatgatctgg
    35821 gcaggagaac attgaacaac gaagagcagg caaacagtgg gagagaatat catgtctggt
    35881 ttatatacac tattggacat atagatgagg ggatggttgc ataaagcctg ttatatagta
    35941 agctagcaac agtcacttaa ctaactaggg agcgcttact gcccttacaa ggttgaaaat
    36001 ttcatcgtgc ctaaagcgcc agaggaaccc agctgaagtt ttagaagaaa ggcgcaacac
    36061 tttgttcggg agggtagtcc tcaaaaaaaa aaaaaaaaaa aaaaaaagga atacaatact
    36121 aatgactccg tctacaatga gccagggggt aatctctttt gttgcggaga agcggggacg
    36181 accgaatgca gtgaacaaga gcgacgctaa ccaatttttc cctagggtct gatctgaacc
    36241 aagcagttag atctgaagta ttagccaggt gctgatctct tgggtaatgg gccgtaagat
    36301 gtatctatac ccagctattc tctctggctt ctctggtttc cccttacgtt ttcctcatcc
    36361 tgcgaattca tctttcattg gacatcaccg taaaatcctt ctgtattgta ccaacagcct
    36421 tcttcctagc gccacacagc agcactcgta ggttcagacc ttcccatttc ccggataata
    36481 cccagtggat ctgctggacg agccggttga tttgtaatcc accgcatgag gaacttccct
    36541 ggcgatatcc tcctagagca taagcctggt cttcctctat gtcgcgtcgg gctgttctct
    36601 ttccattaat gtgattcaga ggacatacac cttatatatt cttccagaag ggcatatccg
    36661 tgcttgctca actgaccatg accagcaagt ctgccgggct ctccgcagcc gaaccgatat
    36721 ttccacaaat tccacgtgtc gccctagtcc cgcaagacga tgcctcgtcc ccattgtcaa
    36781 gtctggagtt gcattccatt gaaccgatag gggccaatac gccgcatagt aggcgcacaa
    36841 ggcatgccgg gtcaacaaaa ccctccgaag tcgacgagat gttcaacgtc gtgcagtcag
    36901 cagcagcaga gaactatgga gctcaagaca caaataggaa aacagcctcg atacacccgc
    36961 gcaggaacac gatctggcga ctagctagcg cgtgcctgat gaactttggc aacggaatga
    37021 acgacagtgc acccggtgcc ctaatccctt atattgagga tgattacggg attggctacg
    37081 ccatcatctc actgatcttc atcgccaacg ccgtcggatt cgttcttgcc gcgcccctta
    37141 ctcacacaat ccaagcccga atcggccacg ccaaaagcta tgctctctcg atgagtctcg
    37201 tcacagcggg ctacgttgcc atcgtatgcc acccgccctt tccggtcgtt gtcacggcgt
    37261 ttctcctcct cggcttcggg atggcgttaa gcatcgcgct taacaatgtc ttctgcgcaa
    37321 acctaaacag ctatgccaca gcactgggct ttttctccgg tgcgtatggc atcggtgggg
    37381 tgatctcccc actattggcc acggccatgg tgtcacacgg catccgctgg acatacttct
    37441 acttcatcac actggtgatt tcgacgttga atatgttgct tgcggctgtc gtctttcgca
    37501 attataagga cgaaggtgcc gcttcgaggg cgcccactca gcaaacatcc ccctcccttg
    37561 cttctcagac ggcccagcca aacgagaatg attcccataa ctcccacact cgcctccaaa
    37621 ccctgaaacg agccatccgg aatctcacaa cgatcctagg atcactcttt atcttcgcat
    37681 accaaggagc cgaagtctct atttccggct ggatcgtctc attcctcatc aactaccgag
    37741 gaggtgattc gcgacgtgtc ggctacgtga gcgctggctt ctgggccgga attaccctcg
    37801 ggcgcttcct ccttgtatac ccggcaaacc gaattggtga ggagcttgcc gtaggactgc
    37861 tggttgtcgg agcgatagcg ttccagctca tgacttggct gatccccaac attgtcggcg
    37921 aagcggtggc ggtggcggtc gtgggcttgc tgctagggcc catgtatcca tgctcgacgg
    37981 ccgtgtttgc gaaactacta ccccggagca ttcagctgac tagcatgagc ttcatcactg
    38041 cgctgggaag tagcgggggt gcagtatttc cctttctgac gggtattctg tcacaagagg
    38101 tgggaacgat agtcctgcat ccaatttgtt tggcgctcta tgcagcgatg gttgtttgtt
    38161 ggtgcttttt gcctgcgatt tcgaagagat cggagtaggg tcgttcgcta taagtttcgt
    38221 actgaatgtg atcaatttca tataactaga aataatggtg tttcacattg ataggtcgga
    38281 tgatagcaga cctctgtagt gtaaagaagg ctgtgtcaga atacctcagc acattataca
    38341 aaactaaaac tatataggag ttgtgcggat gatcctgctg ttaccagtaa tgttacagag
    38401 tagaagataa tgcactgggt agctaaaact gtttagtcag aattagcaac tactgttcta
    38461 aacagttcaa tgaccagcat gttctggaca ttgtggtgct gagcaatttt ggtcgctcgc
    38521 gataggcatg cccagggctc tggaaaatga tgaatcattg tcacatgaac ctccacagcc
    38581 tgtgacaatc ggcgccgtgc ttaccgtaaa agtggacgtg gagtggttca tcaaatcgca
    38641 gagagttcct cagagtgagc atgcacgttt ggaaattctt ggctttccct tggccccatt
    38701 catcaaccaa tctcggaaaa tacactgcgg cacttggaaa ccactagaca gaccttttcg
    38761 gccgatagga cctggatgtg gaccgaggga accttgtctt gccagtaaca gccataactt
    38821 actagtagtt agccgcgttt ccttcccacc gtgagccgtg gcaagccgct tgcgtatttc
    38881 tgatagccac tcagtaatga tcagccttac gcttttgtct gcctcttagt ttctagtcgg
    38941 atttctcact cggagttttg caacacacac tgtgtatgcg ggccgccatt tccacagccg
    39001 agccgagtcc taccgacagt ggtggatggt tccaaccttt agggcttcga atagttgcag
    39061 cacttctctc ccagataaca tatttaatgt cataaggttc cactggtgac tttgtcggcg
    39121 cgtgtatctg tctaggtcat atgaagccgc gtagttcaca gcatagactg ttaatcttgc
    39181 cttatgagct tagaaaccga agcgatggtg cttctatctt agagttttcg tggggcataa
    39241 aaggccccat gagcgcacca gcatcatctg ctggctacgc cctgtgctgg gataaaaatt
    39301 acccaaacta gaaggtatac tcatttaagt tacaaatatt ggtattatgc acattatcac
    39361 ggaagcctag agcttccact tccaggtaag atggccacta acacggtcga atccctgttc
    39421 cattcgtgcc caggcaaccg tcatggtaga tgccaccatc aacgcactga caaagatagc
    39481 catatccaaa tagctacgcg aggtagtctc gccattgtac gtgcgtacca tgactccagc
    39541 caccggggtg cccaccaacc cagccgctcc ctgcaccatg tacatgatac ccgtgatacg
    39601 gggcatctcc tgcaaaccaa agagttccac gagagccggc gagaacagcc caatataggc
    39661 actagcgaag agaccgtaga aaatggtgaa aacaatgaag cagcccttgg ccgccaccag
    39721 gtcatgcaac gtggacccaa gcaaggtact ggggatccag agtgccaccg cacccacagt
    39781 tctgtctttt ttgttgcccg aaaactattt gaatgactga aacctcggcc tttcacgaaa
    39841 agactgagag atccaactgc aatacagtat attactgtca ttttctgggc ctatgtgcca
    39901 cggttgccgt cggccatctg attttgcctc attgttccag gcggggaagt ggagaaggga
    39961 tgcggtccct gaaaattaca cactcgacag tttttgcagg tggcgctttt ggattcgcaa
    40021 cgctatacca tatctggtta gcctcgttca ggtactcccg aaagggctag gctcggtagt
    40081 gaatcgccga cttggcagtt tgggattgtt accatttctt ctccgctaac tatctatagc
    40141 tagtctaatg agagtaaagg tgcaacccgg tctgcaacca ctcggagctc ggacagaatt
    40201 gctggtctta gatactctag agtcatgtac ctgatatgat acctggttgg accttccata
    40261 tccagtcggt aaaatatggg gtcatgtggc aagtgggaag aacttttccg gtagagttcc
    40321 gtaacattcc ataccctgga tcgcattgta acctcaagtc gcaatagtca ccctcttggt
    40381 aatccgttta acccctaggg ctagagacag tcaagcagag ccgtccacac taagatttga
    40441 gtcactcgac atcatcttct cacttcccag ttcctctaag catcccaatt cattccagca
    40501 tcttcctttc tctctgtcct caccagctcc aacataccac aaaatgtcac tcataccaag
    40561 cgttgacagt gctctcgacg caattggaaa cacaccatgt gttcaattga cccgcgtagt
    40621 acctcaggac tgcgctcgag tgttcataaa gctagaaagc ttgaatccta ccggctcgta
    40681 caaggaccgc atggctctct ctgtcatcga ggaagcggag cgtcgtaatg accttcgtcc
    40741 gggaatgaca gtcgtggaag ccaccggcgg cagcaccggg tcgtccctcg ccttcgtctg
    40801 cgccgtcaag ggctacacct tccgtgtagt ctcctccgat gcctttgcga aggagaagct
    40861 taacaccatg actgcgtttg gggcgcacct ggacatcgtg ccgagtgaga atgggaaaat
    40921 cacaccgcaa ctgattccct ctatgcgaga gcgagcacgc cgtattgcca cagaggataa
    40981 agatccttct tcttattact acgccgacca atttagcaat ccagatgtct ttccaggtta
    41041 tgaaaccctt ggtcgtgaga tactagcaca ggttggagaa cctattgacg ccttttgtgg
    41101 cgcggttggg ggcgcaggga tggtgatggg tgtcgggaaa actctgaagc agagctggcc
    41161 ggcgtgccat gtagctgtgc ttgagcctgc ttcggcgcct gccttgacta agggccatgg
    41221 cggcgagcac tcggtggaag gaatcggtat tggattccct cctcctctac tgaacaaaga
    41281 ctggtatgac gaggcacggg cgattgatga gagggaaggg cgttccatgt gtcgacgact
    41341 agcgagggag gagggtcttt tggttggcac ttcttcgggt cttaatgtgg tcgccgcgat
    41401 acagttggct aaggaactgg gtcctgggaa aacagtggtg actgtggggt gtgatactgg
    41461 tctgaagtat gttcgaggaa acctgtacac agatagctga
//
