LOCUS       NKJJ01000002.1         52018 bp    DNA     linear   PLN 19-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   NKJJ01000002
VERSION     NKJJ01000002.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 06:54:43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1103587
            Orig. end    :: 1155605
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(join(1..566,621..1584,1626..1725,1781..1976,
                     2039..2189))
                     /codon_start=1
                     /db_xref="InterPro:IPR013126"
                     /db_xref="InterPro:IPR018181"
                     /db_xref="InterPro:IPR029047"
                     /db_xref="InterPro:IPR029048"
                     /db_xref="InterPro:IPR042050"
                     /db_xref="PFAM:PF00012"
                     /db_xref="PFAM:PF06723"
                     /locus_tag="CAN33_23510"
                     /note="SECRETED:SignalP(1-38)"
                     /product="Hsp70 protein family protein"
                     /protein_id="ncbi_CAN33_23510-T1"
                     /transl_table=1
                     /translation="MARISHQGAAKPFTAWTTIFYLLLVFIAPLAFFGTAHAQDETSPQ
                     ESYGTVIGIDLGTTYSCVGVMQNGKVEILVNDQGNRITPSYVAFTDEERLVGDAAKNQY
                     AANPRRTIFDIKRLIGRKFDDKDVQKDAKHFPYKVVNKDGKPHVKVSAMVLGKMKEIAE
                     GYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRVVNEPTAAAIAYGLDKTGDE
                     RQVIVYDLGGGTFDVSLLSIDNGVFEVLATAGDTHLGGEDFDQRVMDHFVKLYNKKNNV
                     DVTKDLKAMGKLKREVEKAKRTLSSQMSTRIEIEAFHNGEDFSETLTRAKFEELNMDLF
                     KKTLKPVEQVLKDAKVKKSEVDDIVLVGGSTRIPKVQALLEEFFGGKKASKGINPDEAV
                     AFGAAVQGGVLSGEEGTGDVVLMDVNPLTLGIETTGGVMTKLIPRNTVIPTRKSQIFST
                     AADNQPTVLIQVYEGERSLTKDNNLLGKFELTGIPPAPRGVPQIEVSFDLDANGILKVH
                     ASDKGTGKAESITITNDKGRLSQEEIDRMVAEAEEFAEEDKAIKAKIEARNTLENYAFS
                     LKNQVNDENGLGGQIDEDDKQTILDAVKEVTEWLEDNAATATTEDFEEQKEQLSNVAYP
                     ITSKLYGSAPADEDDEPSGHDEL"
     cand_cluster    1..52018
                     /SMILES="C([*])C(-O)"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="neighbouring"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..52018
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /region_number="6"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     protocluster    1..40917
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[1125564:1125846](-),
                     [1123013:1125488](-), [1122654:1122954](-)}"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(join(19068..19367,19427..21901,21978..22259))
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..40917
                     /SMILES="C([*])C(-O)"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     mRNA            complement(join(1..566,621..1584,1626..1725,1781..1976,
                     2039..2189))
                     /locus_tag="CAN33_23510"
                     /product="Hsp70 protein family protein"
     gene            complement(1..2189)
                     /locus_tag="CAN33_23510"
     mRNA            complement(join(3538..4745,4796..4978,5027..5764,
                     5949..6029,6129..6189,6330..6353))
                     /locus_tag="CAN33_23515"
                     /product="Elongation factor Tu GTP binding domain family
                     protein"
     gene            complement(3538..6353)
                     /locus_tag="CAN33_23515"
     CDS             complement(join(3538..4745,4796..4978,5027..5764,
                     5949..6029,6129..6189,6330..6353))
                     /codon_start=1
                     /db_xref="InterPro:IPR000795"
                     /db_xref="InterPro:IPR004160"
                     /db_xref="InterPro:IPR004161"
                     /db_xref="InterPro:IPR005225"
                     /db_xref="InterPro:IPR009000"
                     /db_xref="InterPro:IPR009001"
                     /db_xref="InterPro:IPR015033"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR031157"
                     /db_xref="PFAM:PF00009"
                     /db_xref="PFAM:PF01926"
                     /db_xref="PFAM:PF03143"
                     /db_xref="PFAM:PF03144"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 264.9; E-value:
                     2.8e-80)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_23515"
                     /note="GO_function: GO:0005525 - GTP binding [Evidence
                     IEA]; GO_function: GO:0003924 - GTPase activity [Evidence
                     IEA]"
                     /product="Elongation factor Tu GTP binding domain family
                     protein"
                     /protein_id="ncbi_CAN33_23515-T1"
                     /transl_table=1
                     /translation="MSRHRIKAVQEALWHYYNDVEKSVNYLRGKKTKEVKKKQAPAPAP
                     APAAKAKASTVPVYPVPLSPPASSTAHFSAADFFRDAPWLNIPAHRKADILVEPLYPRL
                     GLLGGAPENSGKVSKLAALAAARKKKEGEKSAAPTPTPPSEVESSRPSSTERKSPALSL
                     RERLASNGKPQKLSEGLQSLRSLNKGSRLGSPSPQKMPSPEPRKQSSPEVTGQADLEPP
                     VSVDKKQEVEAGLNIRAPPSTFASTIVGEATRPKMAEPSHLSASTLDLIKIYGQEFAEP
                     FDFAGPSPDDVVLNAQSSAKGFKSKQSASKSAGDKKSQAGLAEGMNSLSVEEKVNVKSK
                     NLDVLSEYQKTQRKKAMNFAVIGHVDAGKSTLMGRLLADLKAVDQRTLEKYRKEAEKIG
                     KGSFALAWVLDQGSEERARGVTIDIATNKFETESTVFTIVDAPGHRDFVPNMIAGASQA
                     DFAVLVIDSSIGNFESGLKGQTKEHALLVRSMGVQRIIIAVNKMDSVQWDQGRFEEIEQ
                     QVSSFLTTAGFQAKNIAFVPCSGISGDNVTRRSDDPNVSWYKGRTLIEELEATEPYVHA
                     IEKPLRMTIGDVFRGSVQNPLSISGRIDAGSLQVGDQILTMPSGEKATIRSLEVDGEPS
                     DWAVAGQNVTLNLVNIDPIHLRSGDVICRASAPIANVTSFTCKVLAFDHLLPSMVDIHR
                     GRLHVPGRISQLVAALDKVTGASIKKRPKIVAPGTVARIVVEMDQAVPLEAPTRIVLRA
                     GGETVAAGLLE"
     protocluster    6943..52018
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[1129954:1130155](+),
                     [1130222:1130367](+), [1130422:1130691](+),
                     [1130740:1131103](+), [1131154:1132097](+),
                     [1132155:1136216](+), [1136323:1136479](+),
                     [1136532:1137205](+), [1137266:1137415](+)}"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      join(26368..26568,26636..26780,26836..27104,27154..27516,
                     27568..28510,28569..32629,32737..32892,32946..33618,
                     33680..33828)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    6943..52018
                     /SMILES="C([*])C(-O)"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="2"
                     /tool="antismash"
     mRNA            complement(join(6943..7870,7926..9041,9096..9218,
                     9275..10389,10457..10620,11943..12173,12235..12377,
                     12439..13054,13111..13357,13422..13517))
                     /gene="PAN2"
                     /locus_tag="CAN33_23520"
                     /product="poly(A)-specific ribonuclease"
     gene            complement(6943..13517)
                     /gene="PAN2"
                     /locus_tag="CAN33_23520"
     CDS             complement(join(6943..7870,7926..9041,9096..9218,
                     9275..10389,10457..10620,11943..12173,12235..12377,
                     12439..13054,13111..13357,13422..13517))
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002974"
                     /db_xref="InterPro:IPR012337"
                     /db_xref="InterPro:IPR013520"
                     /db_xref="InterPro:IPR015943"
                     /db_xref="InterPro:IPR028881"
                     /db_xref="InterPro:IPR028889"
                     /db_xref="InterPro:IPR030843"
                     /db_xref="InterPro:IPR036322"
                     /db_xref="InterPro:IPR036396"
                     /db_xref="InterPro:IPR036397"
                     /db_xref="InterPro:IPR038765"
                     /db_xref="PFAM:PF00067"
                     /db_xref="PFAM:PF00929"
                     /db_xref="PFAM:PF13423"
                     /gene="PAN2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 216.4; E-value: 1.2e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_23520"
                     /note="MEROPS:MER0030317; GO_component: GO:0031251 - PAN
                     complex [Evidence IEA]; GO_function: GO:0005506 - iron ion
                     binding [Evidence IEA]; GO_function: GO:0020037 - heme
                     binding [Evidence IEA]; GO_function: GO:0016712 -
                     oxidoreductase activity, acting on paired donors, with
                     incorporation or reduction of molecular oxygen, reduced
                     flavin or flavoprotein as one donor, and incorporation of
                     one atom of oxygen [Evidence IEA]; GO_function: GO:0016705
                     - oxidoreductase activity, acting on paired donors, with
                     incorporation or reduction of molecular oxygen [Evidence
                     IEA]; GO_function: GO:0005515 - protein binding [Evidence
                     IEA]; GO_function: GO:0003676 - nucleic acid binding
                     [Evidence IEA]; GO_function: GO:0004535 - poly(A)-specific
                     ribonuclease activity [Evidence IEA]; GO_process:
                     GO:0055114 - oxidation-reduction process [Evidence IEA];
                     GO_process: GO:0000289 - nuclear-transcribed mRNA poly(A)
                     tail shortening [Evidence IEA]; GO_process: GO:0006397 -
                     mRNA processing [Evidence IEA]"
                     /product="poly(A)-specific ribonuclease"
                     /protein_id="ncbi_CAN33_23520-T1"
                     /sec_met_domain="p450 (E-value: 4.2e-45, bitscore: 150.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MAFLNSVAPSLIVGTWICALAYRFIAQKRELRANNKVAAANGCLP
                     LRQWNSTWPLGLDLLVQAFHYDRRQQILKFFLGVVAESGTTFEQNLLFSRGVDTIDPQN
                     IQALLSTQYADFGLGLRPPTFCPLLGSGIFTQDGAQWRHSRERLRPQFMTNRFTNFEQI
                     RSAVDNLISSISDDNAVNLQPLFFRLTFETTLFLLFGQHLPSLQLEGIKNQESDFANAF
                     NLGQEYLAKRGRLGGFYWLLDGRDFREACKTCHEFVDRAVQKALDLTTKKTPGTKTEPY
                     IFIDAFIEETRNPEVLRDQCLNILLAGRDTTACCLTWTLRLLVQHPPVLSKLRAEISDT
                     VGIGPRSPAPTIIQVKSLPYLSLVIKEVLRLYPSVPVNSRAATKTTTLPTGGGPTGTAP
                     ILVRKGEAVGYCVYAMHRRRDIYGADADKFRPERWENDALKDVGWELVTLAGCDVKAME
                     ADWDELSRIPVPAPSVHALPTIATAIAFDDVMELLWVGNEFGRITSFFGPELQRYTSVR
                     AHPATEPVRQIIFHDRGVISLSPKSVHMITRRGLTQWHIAHEEMTDLRCMSFTAQTNRI
                     IVAGCQKSMFTIDIDKGLIIDKLHTEYNYTIMKKSRYLCAATDTGSVNALSLNDFSVVK
                     SWKAHGTAVNDMDARNDLLVTCGFSVRHLGSPIVDPLANVYDLKTLSPLPPIPFHAGAA
                     YVRMHPKLHTTSFVASQTGQLQVVDLMNPNAINLRQANVSFMLGIDLSPSGEALAINDA
                     ECAIHLWGSPAKVHFNEMSKEAEFGDVAPRPPTLDWSPETPLSMIGMPYYHERLFSAWP
                     SHLVFEVGSPPPQVDQALIPYLRPAELGHHAPNPKKTRRYQVENTRALASAEPALIAPN
                     DAAEALAGAKINGETDDDPLLKYSNVEIKYSRFGVDDFDFRFYNQTTFSGLETHIANSF
                     TNALLQLFKFIPYIRNVALHHAASSCIFETCLLCEMGYLFDMLEKASGQNCQATNLLKT
                     FSSYREASNLGLFEENLTNKSLSAAIQAVNRFFLGQISHDFRMISPSSDDLDHRLATVA
                     SESIRCMFCQNEIVRPGNSLVNELNYPAIDIKQARRNPAFRFSNILRASIEREAQNRGW
                     CNYCRRYQQVAIRKSVHRMPQVLMLNAALTNPICRRLWAIPGWLPEEVGIVIEGGQILC
                     FEGEDLKLRVQAKMPGLVVYDLVGLVCEIDIPEHQKAHLVSFINVSISSREPEAKNKWH
                     LFNDFLVTEVDKEEALRFNQPWKIPCVLAYQVQDGRHAMDDTWKDALDTTLLFRDWSLN
                     GGRPVESRVTLSEEEKPTPGTPVALDTEFVDLEKAEIDVKADGSQEIVRPSKSGLARVS
                     VLRGSGIREGVPFIDDYITIKENIVDYVTQYSGIKPGDLDPRVSQHNLVPLKVAYKKLW
                     LLLNLGCVFVGHGLASDFRKVNIQVPKSQTVDTQYLFFHPGKNRRLSLRYLAWAVFKEY
                     IQEEPADDSQGHDSIEDARMALRLWKKFKEYEDAGIVSQILEEIFREGSKLGFRPPPRN
                     GVPTVLSRPGTAVTMQNNSGRNTPSTSDVAGAAASAPATPRQAFRRSIALTPSNGSFAG
                     PGTGDFFSGSPLK"
     mRNA            join(16189..16337,16387..16674,16723..16794,16860..17274)
                     /locus_tag="CAN33_23525"
                     /product="hypothetical protein"
     gene            16189..17274
                     /locus_tag="CAN33_23525"
     CDS             join(16189..16337,16387..16674,16723..16794,16860..17274)
                     /codon_start=1
                     /locus_tag="CAN33_23525"
                     /note="SECRETED:SignalP(1-22); EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CAN33_23525-T1"
                     /transl_table=1
                     /translation="MRGPGTMKAVLCSLAFAVGVAAKDDPDYDPSLNFRPKNVTLSILD
                     YWVGSYYNGTTDVELSFYTGLAANWSHLCPNLINTTVTKKYNNSVLGLTEPSSYNVGYD
                     PVNAFFTMWPRNFNFSTLPDPRWSWESIQYDASLRFALFSSDPTYWVGPRVSNNFNWTL
                     NATQGPPCNGSDIVEWTFYPTPWDIMGNGLYLPDAVLDLQFDEKTANLSLNGYFIGYHA
                     VKVGTETLSTGVLVVGKMKLSFLGVLDAYHSDVLANNTATPTWLRTVGFQNNSLNVGYT
                     STASSVSMGRAVFATIIALTVMAGFV"
     mRNA            complement(join(19068..19367,19427..21901,21978..22259))
                     /locus_tag="CAN33_23530"
                     /product="Male sterility protein family protein"
     gene            complement(19068..22259)
                     /locus_tag="CAN33_23530"
     CDS             complement(join(19068..19367,19427..21901,21978..22259))
                     /NRPS_PKS="Domain: AMP-binding (15-338). E-value: 7.3e-35.
                     Score: 111.9. Matches aSDomain:
                     nrpspksdomains_CAN33_23530_AMP-binding.1"
                     /NRPS_PKS="Domain: TD (680-927). E-value: 7.1e-45. Score:
                     144.8. Matches aSDomain: nrpspksdomains_CAN33_23530_TD.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /codon_start=1
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="InterPro:IPR020806"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="InterPro:IPR036736"
                     /db_xref="InterPro:IPR042099"
                     /db_xref="PFAM:PF00501"
                     /db_xref="PFAM:PF01370"
                     /db_xref="PFAM:PF07993"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     113.7; E-value: 1.3e-34)"
                     /gene_kind="biosynthetic"
                     /locus_tag="CAN33_23530"
                     /note="EggNog:ENOG41; GO_function: GO:0031177 -
                     phosphopantetheine binding [Evidence IEA]; GO_function:
                     GO:0003824 - catalytic activity [Evidence IEA]"
                     /product="Male sterility protein family protein"
                     /protein_id="ncbi_CAN33_23530-T1"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-26, bitscore:
                     88.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1e-05, bitscore:
                     22.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.2e-39, bitscore:
                     130.8, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MGSADSSGRLLTQLVDQQAKDQPDRLYCLHPSSQDADCEWRCITF
                     QQLSAAVNRVSWWIDSRLSGRKQQVLAYIGTNDLRYLVFELACMKTGHAALLLSTRNSQ
                     AAFHHLLLKTSCSVLVDGSERPQLKKVVDQVEIACSDLGLQRWRMDPVGDVFAASPVTS
                     YPHQENFADIEDRPAIIIHSSGTTGLPKPVTLTHGYLATLDQMQTLPVPQGRESAQLFL
                     RHKGEMRFSHGPLFHFIGIVCVCECIFYETPFLLSPDRPLTPDLFSRIMATPNPPRWCL
                     IAPFALQDLWSSEKGRQALQGLSAVNFGGAPLSSATGNAISSHFRLQTLMGSSETGYTP
                     TLLCEDPADWACFEWNPAFEHRMEEVGDGLWELVIPRPSSRRYHGIFHAFPHLSEYRTG
                     DLFEPHPTKPHLWRSKGRADDIIVLSNGEKLNPIDAEHHLESHSLVHRAAIFGQDRFQV
                     ALLVQPKWDELPETWTPQWLKQALEPLMKDANGLLPAHGQIHHNRVAIASCDRPFALAP
                     KGSLRRRETAQLYEDVINALYSDATGYEGSTRDVEKLQESTMEGIEQWLQETVSRILGG
                     ITVDLDVDIVTLGMDSLQVVRLAQVLQDAADRMSQTKQISILWTSAAIYEQATVRRLAS
                     TLFRQLGGHLGAEGEKHAVSFWSREHQLTHAIWQQAQSLQLRGKTVLLTGSTGELGSYL
                     LEELLQDPTITHVYCLNRSADAETRQLARFREKRLADGWLVETSRVKFWQADLSQERLG
                     LTEEEYSYLRERVDIIFHNAWMVNFNLPLSSFRSQLEGTGRLLNLIKDSPRQAAFHFIS
                     SIAAVSGRSTILPETDHIAETLYGPSTVLSQGYAESKYAAEVLCDLVAGETQQTIAIHR
                     VGQLGGPADAEAGMWTTRDWFPALVRTSQTMKELPDSIGSIPVDWVPIDVAARSIVQIG
                     CGRHSGRLASTESNHAEVYHITNPHISHWEPLAQIISQACSTKIIPLRVWVKNLTNRLS
                     DPNLNEEVMRKIPAASLLGFFTSLAESEG"
     aSDomain        complement(join(19344..19367,19427..20143))
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_23530_TD.1"
                     /evalue="7.10E-45"
                     /label="CAN33_23530_TD.1"
                     /locus_tag="CAN33_23530"
                     /score="144.8"
                     /tool="antismash"
                     /translation="VLLTGSTGELGSYLLEELLQDPTITHVYCLNRSADAETRQLARFR
                     EKRLADGWLVETSRVKFWQADLSQERLGLTEEEYSYLRERVDIIFHNAWMVNFNLPLSS
                     FRSQLEGTGRLLNLIKDSPRQAAFHFISSIAAVSGRSTILPETDHIAETLYGPSTVLSQ
                     GYAESKYAAEVLCDLVAGETQQTIAIHRVGQLGGPADAEAGMWTTRDWFPALVRTSQTM
                     KELPDSIGSIPVDWVPIDVAARSIVQ"
     aSDomain        complement(join(21170..21901,21978..22214))
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_23530_AMP-binding.1"
                     /evalue="7.30E-35"
                     /label="CAN33_23530_AMP-binding.1"
                     /locus_tag="CAN33_23530"
                     /score="111.9"
                     /specificity="consensus: hydrophobic-aliphatic"
                     /tool="antismash"
                     /translation="DQQAKDQPDRLYCLHPSSQDADCEWRCITFQQLSAAVNRVSWWID
                     SRLSGRKQQVLAYIGTNDLRYLVFELACMKTGHAALLLSTRNSQAAFHHLLLKTSCSVL
                     VDGSERPQLKKVVDQVEIACSDLGLQRWRMDPVGDVFAASPVTSYPHQENFADIEDRPA
                     IIIHSSGTTGLPKPVTLTHGYLATLDQMQTLPVPQGRESAQLFLRHKGEMRFSHGPLFH
                     FIGIVCVCECIFYETPFLLSPDRPLTPDLFSRIMATPNPPRWCLIAPFALQDLWSSEKG
                     RQALQGLSAVNFGGAPLSSATGNAISSHFRLQTLMGSSETGYT"
     CDS_motif       complement(21593..21652)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23530_0001"
                     /evalue="4.00E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="CAN33_23530"
                     /score="13.4"
                     /tool="antismash"
                     /translation="AIIIHSSGTTGLPKPVTLTHG"
     mRNA            complement(join(22788..23491,23559..23697))
                     /locus_tag="CAN33_23535"
                     /product="Serine hydrolase (FSH1) family protein"
     gene            complement(22788..23697)
                     /locus_tag="CAN33_23535"
     CDS             complement(join(22788..23491,23559..23697))
                     /codon_start=1
                     /db_xref="InterPro:IPR005645"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="PFAM:PF03959"
                     /locus_tag="CAN33_23535"
                     /note="EggNog:ENOG41"
                     /product="Serine hydrolase (FSH1) family protein"
                     /protein_id="ncbi_CAN33_23535-T1"
                     /transl_table=1
                     /translation="MKILCLHGYGTGPNILRYQLSGLMRDADPSWEFHFLSAEVECPPA
                     PDIGSTFPPPYYCWTRSFDAGSIDAAHALIEEAIDEHGPFDGVLGFSQGAAISVSFLLE
                     HKTAYPDEPPPFRFAIFYSPTIPCAADEAYCRSVLGTLSSADQQSLRSGKDKEIAQLPE
                     PVRSVTESLVKVIKGTHSITRESVPFFLDRPLELIPCALHPNVVPTRISIPSLHLRGKN
                     DVPGLDDCGLLVECLCDSNTRRPIIHSAGHDIPRSGPELKQMLSAVEWVVAKSQLPLL"
     mRNA            complement(join(24630..25636,25690..25801))
                     /locus_tag="CAN33_23540"
                     /product="Zinc-binding dehydrogenase family protein"
     gene            complement(24630..25801)
                     /locus_tag="CAN33_23540"
     CDS             complement(join(24630..25636,25690..25801))
                     /NRPS_PKS="Domain: PKS_ER (20-233). E-value: 8.6e-13.
                     Score: 39.7. Matches aSDomain:
                     nrpspksdomains_CAN33_23540_PKS_ER.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="InterPro:IPR020843"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF00107"
                     /db_xref="PFAM:PF08240"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 153.4; E-value: 1.4e-46)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_23540"
                     /note="EggNog:ENOG41; GO_function: GO:0016491 -
                     oxidoreductase activity [Evidence IEA]; GO_process:
                     GO:0055114 - oxidation-reduction process [Evidence IEA]"
                     /product="Zinc-binding dehydrogenase family protein"
                     /protein_id="ncbi_CAN33_23540-T1"
                     /transl_table=1
                     /translation="MGVQRAVIVRERGQVTLADDVPIPALPDDYILVKTQAVALNPTDW
                     KHVDFDSCAGTVVGCDYAGVVEAIGPRVTKPWKKGDRVAGFVHGCNVMQPQGGAFAQYV
                     IAKGDIQFRVPEWMDIDRAACLGVGMMTIGQNLYQSMQLTDPGMVCDDKITDLQRDEKG
                     NDEDIPSILIYGGATSTGSLAIQFAKLSGLRVVTTCSEVNRAWMHELGADIVLDYHDPH
                     VGDQIREVTDDTLELAFDTISTNQSAAICAAALSSSGGCYNALLDVRCPRGDVDTHVSM
                     AYDMIGEPYLMGGKEVQAQLENLSFGAQWVNAVEILLQTRQIASPRFQVKPGSLAGVTS
                     GLDWLRKGKVRASKLVYIVDETLETARLEIPG"
     aSDomain        complement(join(25050..25636,25690..25741))
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_23540_PKS_ER.1"
                     /evalue="8.60E-13"
                     /label="CAN33_23540_PKS_ER.1"
                     /locus_tag="CAN33_23540"
                     /score="39.7"
                     /tool="antismash"
                     /translation="VPIPALPDDYILVKTQAVALNPTDWKHVDFDSCAGTVVGCDYAGV
                     VEAIGPRVTKPWKKGDRVAGFVHGCNVMQPQGGAFAQYVIAKGDIQFRVPEWMDIDRAA
                     CLGVGMMTIGQNLYQSMQLTDPGMVCDDKITDLQRDEKGNDEDIPSILIYGGATSTGSL
                     AIQFAKLSGLRVVTTCSEVNRAWMHELGADIVLDYHDPHVGDQIREVTDDT"
     CDS_motif       complement(25185..25241)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23540_0003"
                     /evalue="6.20E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="CAN33_23540"
                     /score="9.4"
                     /tool="antismash"
                     /translation="SILIYGGATSTGSLAIQFAK"
     CDS_motif       complement(25350..25382)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23540_0002"
                     /evalue="9.80E+00"
                     /label="PKSI-ER_m5"
                     /locus_tag="CAN33_23540"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="AACLGVGMMTIG"
     CDS_motif       complement(25539..25592)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23540_0001"
                     /evalue="2.80E-02"
                     /label="PKSI-ER_m2"
                     /locus_tag="CAN33_23540"
                     /score="7.7"
                     /tool="antismash"
                     /translation="CAGTVVGCDYAGVVEAIGP"
     mRNA            join(26368..26568,26636..26780,26836..27104,27154..27516,
                     27568..28510,28569..32629,32737..32892,32946..33618,
                     33680..33828)
                     /locus_tag="CAN33_23545"
                     /product="Beta-ketoacyl synthase N-terminal domain family
                     protein"
     gene            26368..33828
                     /locus_tag="CAN33_23545"
     CDS             join(26368..26568,26636..26780,26836..27104,27154..27516,
                     27568..28510,28569..32629,32737..32892,32946..33618,
                     33680..33828)
                     /NRPS_PKS="Domain: PKS_KS (13-438). E-value: 1.8e-169.
                     Score: 555.8. Matches aSDomain:
                     nrpspksdomains_CAN33_23545_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (546-860). E-value: 2.4e-97.
                     Score: 317.6. Matches aSDomain:
                     nrpspksdomains_CAN33_23545_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (938-1118). E-value: 1e-25.
                     Score: 82.7. Matches aSDomain:
                     nrpspksdomains_CAN33_23545_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1658-1956). E-value: 2.7e-30.
                     Score: 97.2. Matches aSDomain:
                     nrpspksdomains_CAN33_23545_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (1969-2130). E-value: 1.2e-41.
                     Score: 134.3. Matches aSDomain:
                     nrpspksdomains_CAN33_23545_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (2248-2310). E-value: 9.8e-08.
                     Score: 23.9. Matches aSDomain:
                     nrpspksdomains_CAN33_23545_ACP.1"
                     /NRPS_PKS="type: Type I Iterative PKS"
                     /codon_start=1
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR018201"
                     /db_xref="InterPro:IPR020801"
                     /db_xref="InterPro:IPR020806"
                     /db_xref="InterPro:IPR020807"
                     /db_xref="InterPro:IPR020841"
                     /db_xref="InterPro:IPR020843"
                     /db_xref="InterPro:IPR032821"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="InterPro:IPR036736"
                     /db_xref="InterPro:IPR042104"
                     /db_xref="PFAM:PF00106"
                     /db_xref="PFAM:PF00109"
                     /db_xref="PFAM:PF00550"
                     /db_xref="PFAM:PF00698"
                     /db_xref="PFAM:PF02801"
                     /db_xref="PFAM:PF08659"
                     /db_xref="PFAM:PF14765"
                     /db_xref="PFAM:PF16197"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 175.7; E-value: 2.9e-53)"
                     /gene_kind="biosynthetic"
                     /locus_tag="CAN33_23545"
                     /note="EggNog:ENOG41; GO_function: GO:0016491 -
                     oxidoreductase activity [Evidence IEA]; GO_function:
                     GO:0031177 - phosphopantetheine binding [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]; GO_function: GO:0016740 - transferase activity
                     [Evidence IEA]"
                     /product="Beta-ketoacyl synthase N-terminal domain family
                     protein"
                     /protein_id="ncbi_CAN33_23545-T1"
                     /sec_met_domain="PP-binding (E-value: 2.8e-06, bitscore:
                     24.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 6.3e-96, bitscore: 317.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 3.8e-170, bitscore:
                     562.5, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 6.5e-34, bitscore:
                     113.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MEEHVRDTSGPEPIAIIGMGCRFAGEASSVEGFWDMLRLGRREHG
                     RVPASRYQASAWEHPSHERKGAINHDSGFFLAEDPSHFDAPFFSITSKEAAGMDPVQRI
                     LLEVAYEAFENGGVPMETLPGSATGVYSGCMTNDYELLSTRDIMDMPHNSATGNGKTML
                     ANRLSWFFDLRGPSIMMDTACSSSLTALHLATQALRAGECSQALVTGASLILHPNFTQR
                     LSYMHMLSADGISHSFDSKANGYGRGEGFGAILLKPLSKAMADGDMIRAIVRATGSNQD
                     GRTPGITMPNATAQADLIRSTYSRAGLSMGETSYFEAHGTGTAIGDPTELSAIGASFGA
                     ERKPGDEPLCVGSVKSNLGHTEGAAGVASIIKVVLCLEKGMLVPNAGFSNLNPKIRLEE
                     WGLRLSNSTTPWPSHLLQRASINSFGFGGANAHAILESTAQYLGKTQAPSDSTIEGTPQ
                     VVVVSTHDQSGLDRTADKWTSFLNPCVDGKRKDIALLDVAHTMATRRSQLPFRSFAVVN
                     SLAELRNVMAAGLPTFSRASRKNQAHLAFIFTGQGAQWPRMGVQLLANPVFAASMERSQ
                     QVLQSLDCSWDLLEEIRAGATTSRINRPDRSQPSCCALQVALVDMLRSWGVTPKAVVGH
                     SSGEVGAAYAAGYLTHEDAIRITYFRGVLSQRIAESESRGGMLAAGISAADAQEYLQTL
                     PPESAVVACVNSPSSVTLSGNIEEINLLEKRLQADGCFARKLRVDTAYHSPHMRALADD
                     YKTAIESIQPVDKYNGSISMFSSVTKELLQAADLDASYWVRNLVSPVEFAAAVTKVATM
                     TEAGRGRGRRRVVPVKWAGFLEIGPHEALKGPFNQTLQEANADLASTPYKSLVLRKQDS
                     RQTALQVAGLLWCLGYAINLDTANQSFLESRRPQVSRDLPSYAWNHQSTFWHEPLESAR
                     LRQRKEPRHDLLGMPWDYQNELEPRWRNFLRVSELPWLADHVVAGSIVYPAAGMVSMVA
                     EAARQLAGTTKWLEGIEFNDLDFFRGVVIPPDERGLEIVLHVAPHHGMNGWYEFGIFSL
                     PENSSWVQHAKGAFAPQYADEDGVGCAADWQCTVQRVRQTQAMAKKAEIEAVYEWLSET
                     GGVTLGPTFRSMAGVAFDSESRLYVTGVAPNTKQTMPYERESPCLVHPTSLDSLFQAAV
                     VSCSDALSNHNANIPVGVERLYLSTAFSLQPGDRFDVHVETRYENGVSFTESIASDPSW
                     QQPGMVLQGVRLGRVPTRSGGSTIEEIQQSRFSTLHWAEHVDSSGGLEGRCSGGLQNWL
                     GRVCHTHGDARVLVVTTKDIGQVVEALRDYAPKRSHRPRLQKLTIVLSDPDTEALTNQV
                     KIIKDSLDGCQVLPVASLQDIGTDLLGETAYDAIIVDHPDVWSGDNTKAFFNSLLSITR
                     PDSWIAARATAENHDAAIRNAGHADWEVQGSIEQPGYLLIRRQLAPVELDPTIYILSSA
                     AAESVGPLLYELDGVVNKLGSKIELVDVDKAPDLKEKMIISLLELDRPWTVNWTPDEIS
                     RFQSLLQAKCLLWISQCPGHEASGYAGFGATTGLLRTVRNENPHIVLPQLLVSGKDKDP
                     HNLARSIAHVLQLTLKPRSRPHDLEFYMQDNRLLVPRAITARAVDESMDALLRGPRPTL
                     AELAQDSRPLRLCTKSQDISDARWELDERLNSALPDDLVEVQLHKVSISELASKSGISP
                     EARIAAIEAVGIVRQVGMSIGSAFQVGDEVLCAIPSDAWPSALTTHVRLPASAIWNSPS
                     QQSETQSVSMPVAFAAAYTSLFGSSGASASSVLIVGSVSQTLRATVDCALAAGMQVYVA
                     VDGEDGINGMRSKYVGLHERIIPIHRELDTTVKRLTGGKGVELSVCCLGGSVSRLAARC
                     LAYSGRLVDLSEELNLAALPQTFVDRGCTVSSVRLSRMLREAPRQLQANFHRAVDLLGS
                     DALASVQAYQSFPVSQVADAVAHARDSGTRAIVDLQAPGQVPIVPALPDPAPLPAENTY
                     ILQTALKELQDRGARTDVVRCDAACQEDVKSLLTRAENNRWRVRGIVQCATVLKDGMFE
                     HMDFDAWKQSTEPKVQGTWNLHKAFYSTPLDFFVTLSSIASITGNMGQANYAAGNGYMD
                     ALMIWRRKHHLPGHSINIGLVPDASGVSDVAETPEQRRQRYRHLEGTEILQREVQTLLR
                     VIVQKITRVPAQVIAGLTDTLPRTDGAASWQFDRKFDHRIQVVADEDAAAGVVKTSTLL
                     KKAQSVDEAVRVVNQALQEYLARAMASSAEAIDLELPFSALGVDSLKAAEVQNWVSREM
                     GAELSSFEFIGAQPVRVLAEKIATLSSFVVAT"
     aSDomain        join(26407..26568,26636..26780,26836..27104,27154..27516,
                     27568..27903)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_23545_PKS_KS.1"
                     /evalue="1.80E-169"
                     /label="CAN33_23545_PKS_KS.1"
                     /locus_tag="CAN33_23545"
                     /score="555.8"
                     /tool="antismash"
                     /translation="IAIIGMGCRFAGEASSVEGFWDMLRLGRREHGRVPASRYQASAWE
                     HPSHERKGAINHDSGFFLAEDPSHFDAPFFSITSKEAAGMDPVQRILLEVAYEAFENGG
                     VPMETLPGSATGVYSGCMTNDYELLSTRDIMDMPHNSATGNGKTMLANRLSWFFDLRGP
                     SIMMDTACSSSLTALHLATQALRAGECSQALVTGASLILHPNFTQRLSYMHMLSADGIS
                     HSFDSKANGYGRGEGFGAILLKPLSKAMADGDMIRAIVRATGSNQDGRTPGITMPNATA
                     QADLIRSTYSRAGLSMGETSYFEAHGTGTAIGDPTELSAIGASFGAERKPGDEPLCVGS
                     VKSNLGHTEGAAGVASIIKVVLCLEKGMLVPNAGFSNLNPKIRLEEWGLRLSNSTTPWP
                     SHLLQRASINSFGFGGANAHAILESTA"
     CDS_motif       27012..27059
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23545_0001"
                     /evalue="1.60E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="CAN33_23545"
                     /score="17.1"
                     /tool="antismash"
                     /translation="GPSIMMDTACSSSLTAL"
     CDS_motif       27250..27288
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23545_0002"
                     /evalue="9.50E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="CAN33_23545"
                     /score="12.4"
                     /tool="antismash"
                     /translation="FDSKANGYGRGEGF"
     CDS_motif       join(27481..27516,27568..27579)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23545_0003"
                     /evalue="7.30E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="CAN33_23545"
                     /score="11.9"
                     /tool="antismash"
                     /translation="YFEAHGTGTAIGDPTEL"
     CDS_motif       27643..27687
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23545_0004"
                     /evalue="2.00E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="CAN33_23545"
                     /score="10.8"
                     /tool="antismash"
                     /translation="GSVKSNLGHTEGAAGV"
     CDS_motif       28225..28278
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23545_0005"
                     /evalue="6.80E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="CAN33_23545"
                     /score="18.4"
                     /tool="antismash"
                     /translation="FIFTGQGAQWPRMGVQLLA"
     aSDomain        join(28228..28510,28569..29227)
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_23545_PKS_AT.1"
                     /evalue="2.40E-97"
                     /label="CAN33_23545_PKS_AT.1"
                     /locus_tag="CAN33_23545"
                     /score="317.6"
                     /specificity="Minowa: mmal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="consensus: pk"
                     /tool="antismash"
                     /translation="IFTGQGAQWPRMGVQLLANPVFAASMERSQQVLQSLDCSWDLLEE
                     IRAGATTSRINRPDRSQPSCCALQVALVDMLRSWGVTPKAVVGHSSGEVGAAYAAGYLT
                     HEDAIRITYFRGVLSQRIAESESRGGMLAAGISAADAQEYLQTLPPESAVVACVNSPSS
                     VTLSGNIEEINLLEKRLQADGCFARKLRVDTAYHSPHMRALADDYKTAIESIQPVDKYN
                     GSISMFSSVTKELLQAADLDASYWVRNLVSPVEFAAAVTKVATMTEAGRGRGRRRVVPV
                     KWAGFLEIGPHEALKGPFNQTLQEANADLASTPY"
     CDS_motif       join(28465..28510,28569..28639)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23545_0006"
                     /evalue="3.70E-13"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="CAN33_23545"
                     /score="41.5"
                     /tool="antismash"
                     /translation="GVTPKAVVGHSSGEVGAAYAAGYLTHEDAIRITYFRGVLS"
     CDS_motif       29006..29053
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23545_0007"
                     /evalue="2.00E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="CAN33_23545"
                     /score="13.7"
                     /tool="antismash"
                     /translation="LDASYWVRNLVSPVEFA"
     aSDomain        29462..30001
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_23545_PKS_DH.1"
                     /evalue="1.00E-25"
                     /label="CAN33_23545_PKS_DH.1"
                     /locus_tag="CAN33_23545"
                     /score="82.7"
                     /tool="antismash"
                     /translation="HDLLGMPWDYQNELEPRWRNFLRVSELPWLADHVVAGSIVYPAAG
                     MVSMVAEAARQLAGTTKWLEGIEFNDLDFFRGVVIPPDERGLEIVLHVAPHHGMNGWYE
                     FGIFSLPENSSWVQHAKGAFAPQYADEDGVGCAADWQCTVQRVRQTQAMAKKAEIEAVY
                     EWLSETGGVTLGPTFRSM"
     CDS_motif       29546..29623
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23545_0008"
                     /evalue="2.10E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="CAN33_23545"
                     /score="33.0"
                     /tool="antismash"
                     /translation="WLADHVVAGSIVYPAAGMVSMVAEAAR"
     aSDomain        31622..32515
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_23545_PKS_ER.1"
                     /evalue="2.70E-30"
                     /label="CAN33_23545_PKS_ER.1"
                     /locus_tag="CAN33_23545"
                     /score="97.2"
                     /tool="antismash"
                     /translation="DARWELDERLNSALPDDLVEVQLHKVSISELASKSGISPEARIAA
                     IEAVGIVRQVGMSIGSAFQVGDEVLCAIPSDAWPSALTTHVRLPASAIWNSPSQQSETQ
                     SVSMPVAFAAAYTSLFGSSGASASSVLIVGSVSQTLRATVDCALAAGMQVYVAVDGEDG
                     INGMRSKYVGLHERIIPIHRELDTTVKRLTGGKGVELSVCCLGGSVSRLAARCLAYSGR
                     LVDLSEELNLAALPQTFVDRGCTVSSVRLSRMLREAPRQLQANFHRAVDLLGSDALASV
                     QAYQSFPVSQVADAVAHA"
     aSDomain        join(32555..32629,32737..32892,32946..33197)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_23545_PKS_KR.1"
                     /evalue="1.20E-41"
                     /label="CAN33_23545_PKS_KR.1"
                     /locus_tag="CAN33_23545"
                     /score="134.3"
                     /specificity="KR stereochemistry: (unknown)"
                     /specificity="KR activity: active"
                     /tool="antismash"
                     /translation="APGQVPIVPALPDPAPLPAENTYILQTALKELQDRGARTDVVRCD
                     AACQEDVKSLLTRAENNRWRVRGIVQCATVLKDGMFEHMDFDAWKQSTEPKVQGTWNLH
                     KAFYSTPLDFFVTLSSIASITGNMGQANYAAGNGYMDALMIWRRKHHLPGHSINIGLV"
     CDS_motif       32997..33026
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23545_0009"
                     /evalue="5.30E-04"
                     /label="PKSI-KR_m3"
                     /locus_tag="CAN33_23545"
                     /score="13.2"
                     /tool="antismash"
                     /translation="PKVQGTWNLHK"
     CDS_motif       33048..33158
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_23545_0010"
                     /evalue="5.60E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="CAN33_23545"
                     /score="63.9"
                     /tool="antismash"
                     /translation="LDFFVTLSSIASITGNMGQANYAAGNGYMDALMIWRRK"
     aSDomain        join(33552..33618,33680..33798)
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_23545_ACP.1"
                     /evalue="9.80E-08"
                     /label="CAN33_23545_ACP.1"
                     /locus_tag="CAN33_23545"
                     /score="23.9"
                     /tool="antismash"
                     /translation="LARAMASSAEAIDLELPFSALGVDSLKAAEVQNWVSREMGAELSS
                     FEFIGAQPVRVLAEKIAT"
     mRNA            complement(join(33966..34174,34270..34421,34491..34691,
                     34770..34987))
                     /locus_tag="CAN33_23550"
                     /product="short chain dehydrogenase family protein"
     gene            complement(33966..34987)
                     /locus_tag="CAN33_23550"
     CDS             complement(join(33966..34174,34270..34421,34491..34691,
                     34770..34987))
                     /codon_start=1
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF00106"
                     /db_xref="PFAM:PF08659"
                     /db_xref="PFAM:PF13561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     132.1; E-value: 4.1e-40)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_23550"
                     /note="EggNog:ENOG41; GO_function: GO:0016491 -
                     oxidoreductase activity [Evidence IEA]"
                     /product="short chain dehydrogenase family protein"
                     /protein_id="ncbi_CAN33_23550-T1"
                     /transl_table=1
                     /translation="MSFPYKHILVLGATAGIGRALASRFVQSEVKVTVVGRRKERLDEF
                     LQEHGEDKANAVQFDISDLDKIPGFAAEIMTTYPTIDSVFMNAGIMLPTDMTDPEKFDL
                     PSFYKQMHVNFTSYVALTHAFLPYLTKEGGHTSLIYTTSNLSIVPATWMPAYSASKAAL
                     NAFILCLRDQLRKSSVKIIEVSPPAVQSELHDYMGEEGRKVGMPLKEFTAEAFQGLLDG
                     KDQIVVGSLGPAEVFLDIVNKRRAATTQLAKMMRGEK"
     mRNA            join(35892..36161,36217..37683)
                     /locus_tag="CAN33_23555"
                     /product="hypothetical protein"
     gene            35892..37683
                     /locus_tag="CAN33_23555"
     CDS             join(35892..36161,36217..37683)
                     /codon_start=1
                     /locus_tag="CAN33_23555"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CAN33_23555-T1"
                     /transl_table=1
                     /translation="MDSAFPKRPSFVRYGPYTYDDYGVTVANIPRASSQTLATLFPTNP
                     VTAPSRRPVKRWIAAQLQHFGIPYQPSNTIAQLLALLEREYKDGKCSYESPSVRLLDKT
                     MYEMYNAVQEAYQQQKAEWRKKKFARQVSPSDEALFDPFLFMAKYFLDKENGVPDKTKQ
                     TEAIVLHNVYNQQFVSTALSIPGLSFHISHPATVIGWADTFEEGLDAGFASLSQNHVKE
                     YVPTFEANFDHCRFLTKYFLSLDYPYEMGVPARDRTVEPVQLMPQLYFDVREKLRKEVA
                     NINGLLIATTPGRGGTWTLITWSEYADKLTGVVSKIHAASMNEKMYDDTLISLVWQSKL
                     SRHTLFKQCVKPNNNTSALRLSQLQGQYVIRCNAIDPWGYEDFSLDINAPRRNDPAARA
                     TFSLGKLQGAMILALDCDKVDQMRKILEKKSTATQHSNPESDDDNEMDEHLTVHRFRDD
                     DAKWRVYLQYAGTCNGLNQVDEHNEQVGFIDFNVDPERSDDDEKALGYGLAYGRGLIVG
                     PKYMTSRKSDKGEILEIEVFKWTSDTVRVAAEWNAFNFWGGFEARFRVGERAMTMTKGY
                     EL"
     mRNA            complement(join(38596..38739,38887..39191,39241..39447,
                     39494..40108,40158..40425,40490..40565,40630..40664,
                     40747..40796,40878..40917))
                     /gene="HSE1"
                     /locus_tag="CAN33_23560"
                     /product="ESCRT-0 subunit protein hse1"
     gene            complement(38596..40917)
                     /gene="HSE1"
                     /locus_tag="CAN33_23560"
     CDS             complement(join(38596..38739,38887..39191,39241..39447,
                     39494..40108,40158..40425,40490..40565,40630..40664,
                     40747..40796,40878..40917))
                     /codon_start=1
                     /db_xref="InterPro:IPR001452"
                     /db_xref="InterPro:IPR002014"
                     /db_xref="InterPro:IPR004152"
                     /db_xref="InterPro:IPR008942"
                     /db_xref="InterPro:IPR036028"
                     /db_xref="PFAM:PF00018"
                     /db_xref="PFAM:PF00790"
                     /db_xref="PFAM:PF03127"
                     /db_xref="PFAM:PF07653"
                     /db_xref="PFAM:PF14604"
                     /gene="HSE1"
                     /locus_tag="CAN33_23560"
                     /note="GO_function: GO:0005515 - protein binding [Evidence
                     IEA]; GO_process: GO:0006886 - intracellular protein
                     transport [Evidence IEA]"
                     /product="ESCRT-0 subunit protein hse1"
                     /protein_id="ncbi_CAN33_23560-T1"
                     /transl_table=1
                     /translation="MFRAQQNAFDDAVAKATDENLTSENWEYILDVCDKVGAEESGAKD
                     AVAAMIKRLAHRNANVQLYTLELANALAQNCGPKIHRELASRSFTDALLRLANDRVSWT
                     FTDEEHRTYTEQNTHQQVKSKILERMQEWTEMFASNPDFGIMEQAYMKLKTQNPNLQPP
                     SKPGKREITDADRQKEEEELQMALALSIREKATIAPAPQPEASSSAAPVNQTQAPAATS
                     QAVPSGTSAATVSRVRALFDFQPSEPGELQFRKGDVIAVLESVYKDWWKGSLRGQTGIF
                     PLNYVEKLPDPTVEELQREAQMEADVFGQIKNVEKLLTLLSTRSSELNVQDNEEITALY
                     HSTLAIRPKLIELIGKYSQKKDEFTQLNEKFIKARRDYESLLEASMAHPAQSQYGRPAQ
                     PPYGYPGAAPVGYPQGPPQADPQRYFSPRPQAETQAPPANAPAFYGTEQAHAYPPTSQS
                     PDPRQTPPAGAPYQQQQPQQQRQPSSESYQPVYHRPESTYENPQELGTSVYDSPVEHPA
                     SQRPPYPGAVQVPAAPPPMHQPPPVPGTSTTPTPYPALNAGGGYQAYNPSQTDVSNPAS
                     FYR"
     mRNA            complement(join(42353..42457,42512..42846,42899..42998,
                     43055..43345,43429..43816,43921..44366,44432..44622,
                     44682..45027))
                     /gene="STE20"
                     /locus_tag="CAN33_23565"
                     /product="signal transducing kinase of the PAK"
     gene            complement(42353..45027)
                     /gene="STE20"
                     /locus_tag="CAN33_23565"
     CDS             complement(join(42353..42457,42512..42846,42899..42998,
                     43055..43345,43429..43816,43921..44366,44432..44622,
                     44682..45027))
                     /codon_start=1
                     /db_xref="InterPro:IPR000095"
                     /db_xref="InterPro:IPR000719"
                     /db_xref="InterPro:IPR008271"
                     /db_xref="InterPro:IPR011009"
                     /db_xref="InterPro:IPR017441"
                     /db_xref="InterPro:IPR033923"
                     /db_xref="InterPro:IPR036936"
                     /db_xref="PFAM:PF00069"
                     /db_xref="PFAM:PF00786"
                     /db_xref="PFAM:PF07714"
                     /db_xref="PFAM:PF14531"
                     /gene="STE20"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 176.1;
                     E-value: 1.6e-53)"
                     /gene_kind="regulatory"
                     /locus_tag="CAN33_23565"
                     /note="GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA]; GO_function: GO:0005524 - ATP binding
                     [Evidence IEA]; GO_function: GO:0004674 - protein
                     serine/threonine kinase activity [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /product="signal transducing kinase of the PAK"
                     /protein_id="ncbi_CAN33_23565-T1"
                     /sec_met_domain="Pkinase (E-value: 2.4e-71, bitscore:
                     236.5, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MNHDSFSSLKFRRSSSKLHKDPPSFSSRILKSQQSNTSLKRHPSA
                     PVYPRSSTGGSREHSRTRSNAYGSSSSSLEQNSGGPSPVLAGNQPGYFSNTSNPSKSRP
                     PHSGRFSLTEQRKYHRDRSPKTPNLRSATSPDSRGLRQSASFTALQNRMETFVHRTTDN
                     DRPANPKRLSDEGGGGHVRLPRGIKISAPENPVHVTHVGYDNQTGQFTGLPKEWQRLLQ
                     ENGISKKEQEEHPQTMVDIMRFYEKNAQGDDEVWHKFDHAYPQPQSVSSPISGGQTNAV
                     GAGSYGPTSARTSPPTSPRFPQNHEGSFENPRAPPPIPRGPSAATPAAAPARPPQEAYS
                     PPQFDTPPIPETEPLQSEPKPQLSRSNSRANGTPVPWQSHNVPTPAQYQQKQEQAMAAA
                     QQAIATIQLDRSRSQRQQQPTRQEQKQPSVQSPPHHVSPVDEAARAAPAARPGSDLVRI
                     GQGASGGVFTAYENNTNKCVAIKQMNLDLQPKKDLIINEILVMKDSKHKNIVNFLDSYL
                     HGLDLWVVMEYMEGGSLTDVVTFNIMSEGQIAAVCRETLSGLQHLHSKGVIHRDIKSDN
                     ILLSMEGNIKLTDFGFCAQINDSHNKRNTMVGTPYWMAPEVVTRKEYGRKVDIWSLGIM
                     AIEMIEGEPPYLTESPLRALYLIATNGTPTIKDEHNLSPVFRDFLHLALKVDPEKRASA
                     HDLLKHPFMSLCAPLNHLSPLVKAARASRAQEKAQKGGA"
     mRNA            complement(join(50349..50842,50896..51577,51674..52018))
                     /locus_tag="CAN33_23570"
                     /product="Permease for cytosine/purines uracil thiamine
                     allantoin family protein"
     gene            complement(50349..52018)
                     /locus_tag="CAN33_23570"
     CDS             complement(join(50349..50842,50896..51577,51674..52018))
                     /codon_start=1
                     /db_xref="InterPro:IPR001248"
                     /db_xref="InterPro:IPR026030"
                     /db_xref="InterPro:IPR038271"
                     /db_xref="PFAM:PF02133"
                     /locus_tag="CAN33_23570"
                     /note="EggNog:ENOG41; GO_component: GO:0016021 - integral
                     component of membrane [Evidence IEA]; GO_component:
                     GO:0016020 - membrane [Evidence IEA]; GO_function:
                     GO:0022857 - transmembrane transporter activity [Evidence
                     IEA]; GO_process: GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /product="Permease for cytosine/purines uracil thiamine
                     allantoin family protein"
                     /protein_id="ncbi_CAN33_23570-T1"
                     /transl_table=1
                     /translation="MDFKTLEDGNPIEPKQATASVEEHALVKPSGFFARIRYYEELLDR
                     KMGVESHSLDRVLPEERKPPNTLAMAFIWASATMNLSCFSTGFMGKEFGLTLGQTIAIM
                     ICATFLGAALTGWCATMGPGTGLRQVAISRYSFGFYPSSIIAALNVVEQLGWASVSCIT
                     GGQALRAVSDNHISMVVGVVIVACVSLCFSFFGLRAVMTIEQYIWMVSFVVFIIVYGES
                     AHHASLSDPGTVSGLTKSGNVLSLISVIYGSSASWCSIVSDFYVHYPVNTSKVKVFIYT
                     TLGISLPTCIGMLLGACIASALDGNPEWAAAYDQGTGEILQTIIYPRKFAKFLLVLLVL
                     CGIGMNCIAIYAGSLSAQLFAKPFQKIPRIIWTLLVFACILVIGIAGRDHLLTVLDNFL
                     SLLGYWNTSFFVILFCEHYFFRNGNLANYDLDAWNTPSKLPVGYAGLTAFLCGAAGWIV
                     GMDETYYVGALARKIGTDGGDIANELAFVFTSLSYIPLRKLELKYVGR"
ORIGIN
        1 ttacagttca tcatgcccgc tgggctcgtc atcctcgtcc gccggcgcag agccatacag
       61 cttgctggtg atcgggtacg ccacgttcga gagctgctcc ttctgctcct cgaagtcctc
      121 agtggtggca gtggcagcgt tgtcctcgag ccactcagtc acctccttga cggcgtccag
      181 gatggtctgc ttgtcgtcct cgtcgatctg gccacccagt ccgttctcgt cgttgacctg
      241 gttcttcagg ctgaacgcgt agttctccag ggtgttgcgg gcctcgatct tggccttgat
      301 ggccttgtcc tcctcggcga actcctcggc ctcggcgacc atgcggtcaa tctcctcctg
      361 ggagagacga cccttgtcgt tggtgatggt gatggactcg gccttgccgg tgcccttgtc
      421 gctggcgtga accttcagga taccgttggc atccaggtcg aaggagacct caatctgagg
      481 aacaccacga ggagccgggg gaatgccggt aagctcgaac ttgccgagca ggttgttgtc
      541 cttggtcagg gaacgctcac cctcgtctgt aacagttagc aggcattcca gggttctcga
      601 tcaaggcata agacacttac aaacttggat gaggacggtg ggctggttat cagcggcggt
      661 ggagaagatc tgggacttgc gggtggggat gacagtgttg cgggggatga gcttggtcat
      721 gacaccacca gtggtctcaa tacccagggt cagggggttg acatccatca gaacaacgtc
      781 gccggtaccc tcctcaccgg aaaggacacc accctggacg gcagcaccga aagcaacagc
      841 ctcatcaggg ttgataccct tgctggcctt cttgccaccg aagaactcct cgaggagagc
      901 ctggaccttg gggatacggg tagaaccacc gacgaggacg atgtcgtcaa cctcggactt
      961 cttgaccttg gcatccttga gcacctgctc aacaggcttc agggtcttct tgaagaggtc
     1021 catgttcagt tcctcgaact tggcgcgggt gagggtctcg gagaagtcct cgccgttgtg
     1081 gaaggcctcg atctcaatac gggtggacat ctgggaagac agagtacgct tggccttctc
     1141 aacctcgcgc ttcagcttac ccatggcctt gagatccttg gtgacatcga cgttgttctt
     1201 cttgttgtag agcttgacga agtggtccat gacacgctgg tcaaagtcct caccacccaa
     1261 gtgggtgtca ccagcggtag ccaagacctc gaagacaccg ttgtcgatgg acaggaggga
     1321 gacatcgaaa gtaccaccac caagatcgta gacgataacc tggcgctcat caccagtctt
     1381 gtccaaaccg taggcgatag cggcggcggt gggctcgttg acgacacgga gaacgttcag
     1441 gccggcaatg gtaccagcgt ccttggtggc ctgtctctgg gcgtcgttga agtaggcggg
     1501 gacggtgaca acggcgtggg taaccttctt tccaaggtag ccctcggcga tctccttcat
     1561 cttaccaaga accatggcgg aaacctcctc ggggtcaggg tcttgggggt ctggttgaca
     1621 tcgaccttga cgtggggctt gccgtccttg ttgacgacct tgtaggggaa gtgcttggcg
     1681 tccttctgga catccttgtc atcgaacttg cgaccgatca gacgcctagg gaacgtcagt
     1741 aacagatttc cccgaaactc gcgagaagca gaaaacttac ttgatgtcaa agatggtccg
     1801 tctggggttg gcggcgtatt ggttcttggc ggcgtcaccg accaggcgtt cctcatcggt
     1861 gaaagcgacg tatgaagggg tgatacggtt tccttggtcg ttcacgagaa tttcgacctt
     1921 tccattctgc ataacaccga cacaggagta ggtggttccc agatcaatac caatgactat
     1981 ttagaacaga taatgttagt gtgctttttt cactatgcct ggaaaactct ctgcttacca
     2041 gttccgtagc tctcttgagg cgacgtctca tcctgagcgt gtgcggtgcc gaagaaggcg
     2101 aggggggcaa tgaaaacaag caacaagtag aagatggtgg tccaagccgt gaagggcttg
     2161 gctgcaccct gatgcgagat gcgcgccatg atgtgtgtaa tgtcctttca ccggaggaca
     2221 cgtagtagac ttttaatcga cgagctgctc aattggagac agcagcgaat gaaagtggat
     2281 atgctgtaaa agaatcctcc tattcctcgt acacagtttt ttccccggca cgaagaaaga
     2341 agaaaaaact aaatacaatc caacccagat gagaacggga aggaaaggga agaaagagcg
     2401 aagagggggg gaggagggaa ggggagggaa gatagttggg tgaaagaagg cgacgacgga
     2461 gagaagaaag agtgtccaga gaagctccgg ccagcttctt gtatggcttg ccagcggcaa
     2521 agaaagcgca gcggccatgc tggccttttc gcgggtatct gactttaagg ttactcctcg
     2581 gtctgtgatt ggcccccgac gcgtccaggg cagggctgag tcagcgtgca cggccaccgc
     2641 ccggtggttc tgccggcgga aaaatggaag gagttcgtcc atttggggaa aggcggtcca
     2701 ccgaacttgc tagaatcgtc gcgtgattcg ctcgcttcgg ttaggcgttc ttcactcctc
     2761 caggggaact ttgcctcttt cggcacttgg acaactggct gttccgttcc ttcggcgccc
     2821 tttgccggga gattgaccct gctgagtccg ggggtttacg ctgaaggatg atgagagggc
     2881 gcgaaaaaaa aaggggccag cctgtcaaga actcgtcaat caccacatgg ccagattcca
     2941 ctgttgacca tcattgagtc aaatcattac tcctttttga gtcacagaga tcaccccagg
     3001 gtcttccggt ggaagaagtg gatacatcct ccccactcag gaggcgcatc ctagcttggc
     3061 ctgaattcct gaattattga gccagccaag acctcatgtt tctgccagcc tggccagatc
     3121 gtttgatctt tgtttcagtt gatacggctg aatggggccc tttctctctc tcagccacca
     3181 agggtaccat tcgagcagta ggaactacca gcacactagt agccaaacat gatactcttg
     3241 tatagtaaga ttagtagtag tcacagtcaa agcatcattt tcactccata atatgatgat
     3301 cagtactagt aagtagtagg agtatcagta gtagtgatag gtcattatca atttgccgat
     3361 cacgatatat tattatcggt agctagtaag tactactact attgaatcaa ggacaccgaa
     3421 gtggcgcgga gagtaaatta tatatataat gtgtaaatgt gcctatgtaa gtagaggaac
     3481 atcctcgtta gatccaatat atatatatgg tccctcacaa tgcactcagg ccaccatcta
     3541 ctctagcaat ccggcggcca ccgtttcacc tccagctcgt agtacaatgc gtgtgggcgc
     3601 ctccagaggt accgcctggt ccatctctac cactatccgt gccacagtac cgggagcaac
     3661 aatcttgggc cttttcttga tgcttgcgcc agtcaccttg tccaacgctg cgaccagctg
     3721 gctgatccgg ccgggtacgt gcagccgacc ccggtggatg tccaccatgc tgggcaacag
     3781 atggtcaaag gccagcacct tgcatgtaaa ggacgtaaca ttggcaatgg gtgccgaggc
     3841 acggcaaatg acatcgccag atcggagatg gatgggatca atgttgacca ggttgagcgt
     3901 gacgttctga cccgctaccg cccagtcgct gggctcccca tccacttcca agctgcgtat
     3961 cgtggccttt tcgccactag gcatcgtgag gatctgatca ccaacctgga gactgccagc
     4021 atcgatgcga ccggatatgg aaagaggatt ctggacgctg ccccggaaga cgtcgccaat
     4081 ggtcattctc aacggcttct caatggcatg gacgtaaggt tccgtggcct caagctcctc
     4141 gatcaaagta cgacccttgt accatgagac attcgggtcg tcactgcgcc tggtaacgtt
     4201 atcgccgctg atacccgagc aaggcacgaa tgcgatattc ttggcttgga atccagcagt
     4261 ggttaggaat gaggaaacct gctgttcaat ctcctcaaag cgaccttggt cccattggac
     4321 agagtccatc ttgttcacag caatgataat cctctgcaca cccatactcc gcacgaggag
     4381 agcatgctcc tttgtttgac ctttcagacc agactcgaaa ttgcctatgc tggaatcgat
     4441 gacaaggacg gcaaaatcgg cctgactggc gcccgcaatc atattgggta caaagtcccg
     4501 atgacccgga gcatccacga tcgtaaacac cgtactctcc gtctcaaatt tgtttgttgc
     4561 aatatcaata gtaacaccac gagccctctc ctcggagcct tgatccaaca cccaggcaag
     4621 ggcaaatgat cctttcccga ttttttcagc ttctttgcga tatttctcca gcgtgcgctg
     4681 atcgacagct ttgaggtcgg ccagcaggcg tcccatcaac gtactctttc ctgcgtcgac
     4741 atgacctaat cgcttgtcag tggcgtccac cacagagaga cgggtagtaa cgaaccgata
     4801 acggcgaagt tcatggcttt cttccgttgc gttttctgat actcagacag cacatctagg
     4861 ttcttgctct tcacattcac cttctcctct acactcaggc tgttcatgcc ttcagccaaa
     4921 ccagcctggg atttcttgtc acctgctgac ttagaagcag attgtttcga tttgaagcct
     4981 gcatgtccat tagggaggat ctatatcttg cgccgaatag ccaaaccttt tgcagagctc
     5041 tgagcattca agacaacatc gtcggggctt gggcctgcaa aatcaaaggg ttcagcaaat
     5101 tcttgaccgt atatcttgat gagatctaat gtgctggcag ataggtggct gggctcggcc
     5161 atctttgggc gtgtcgcttc tccaacgatc gtgctggcaa atgtagatgg tggtgcacgg
     5221 atgttgagac cggcttctac ttcctgcttc ttgtcgactg acacgggtgg ttccaaatct
     5281 gcctgcccag tgacctccgg actgctttgt tttcttggct ctggggacgg cattttctgg
     5341 ggcgaagggc ttcccagtcg cgatccctta ttgagtgacc gaagcgattg cagaccctct
     5401 gacaacttct gcggcttgcc attgctagcg agtctctcac ggagagaaag ggcagggctc
     5461 tttcgctcag tggaagacgg ccgggaactt tcaacttccg acggaggtgt aggagttgga
     5521 gcagcagatt tctccccctc tttcttcttg cgcgcagcag ccaaagcagc caacttggac
     5581 accttccccg aattctcagg agctcctcca agcagaccca atcggggata tagaggctca
     5641 acgagtatgt ccgccttacg gtgtgcaggt atgttaagcc acggtgcatc gcgaaagaag
     5701 tcggctgctg agaaatgtgc agttgaagag gccggaggag ataacggaac aggatataca
     5761 ggcactagga agtctgttag aacatacttc aacttccgta atggcgttag ttcaaagcaa
     5821 tcaatcacaa ggggtaagag taatactcac agtttccgaa actcagaccg aaaatacgtt
     5881 taggtataag gcaacttgcg ggtgacccaa gcccaaccac catagtgaac acgagcagat
     5941 gcgcttacct gtgcttgctt ttgccttggc agctggagcc ggagccggag ccggagcctg
     6001 tttcttcttg acttctttcg tctttttacc tgcacccaat ggttctgatt agcatccaga
     6061 gaagcagcat gccattcctg ctggaatgca accaaaattt ctcttccgga aaaggagtga
     6121 taacgcacct ctcaagtagt taacagactt ctcaacatca ttgtagtagt gccatagcgc
     6181 ctcttgcacc tcatcgcgag acgcggtgac agcagggtcc ccgcacggag ctggttcaac
     6241 acttccgtag tgcactgctc aaggaactct tcctcctcgg gatccgggga gtcatagtca
     6301 tcgtcaaagt catcttcgtc gtagctgaca gctttaatgc gatggcgcga catggtggtg
     6361 tgtgttgttg acgggagcgg ggcaggttgc tagggagggg ttttccggga gacggtaggt
     6421 ttaacaaggg attggagtat tattgagagt gacaaatgag aaaggcaacg atttaaataa
     6481 aaagcacgtt atgtgcttgg gtaaatgccc gcgtgtgaaa gggccaaaag tgtagagggt
     6541 ggagttggca aaacagagag ccgagtcgga ggttgtcgtt gtggaggagc tgatcgaatc
     6601 ccaccacgtc attccccgct cggtggcctc aggccggtaa actactgcga atggctcttc
     6661 caatacgcat atcctccaga agcgatctac ggcgccttat ttccaagcta cattctatgt
     6721 gctgcttgtt ttttttcgaa ttgtctgttg aatagataaa ttgggttatt ttctatctat
     6781 cgagtgacat gtgatgtcac tcccaaattt acttcatgta tagccaacta tgacaggaca
     6841 tccaaatgtc gcctctatct tgagaacttg tcgatatagc aagtcgataa catcatatgc
     6901 aaacgtcgtt aaagatctat actccaattc agacggagat gttcacttca ggggacttcc
     6961 actgaagaag tcacccgttc cagggccagc aaagctgccg ttgctgggcg tcagagcgat
     7021 ggagcgtcgg aacgcctgtc tgggagtggc tggggcacta gcagcggcgc cggcaacatc
     7081 agaagtgctg ggagtattgc gaccgctgtt gttctgcatc gtaaccgccg ttccggggcg
     7141 ggagagcacg gttgggacac cgttcctggg agggggtcgg aatccaagct tagagccttc
     7201 gcggaagatc tcctccaata tttgagacac aatgcctgca tcttcgtatt ctttaaattt
     7261 cttccataga cgcagtgcca tgcgtgcgtc ttcaatggag tcgtgtcctt ggctgtcatc
     7321 ggccggttcc tcttggatgt attccttgaa caccgcccag gccagataac gaaggctcag
     7381 acggcgattc ttcccggggt ggaagaataa gtattgggtg tccacggtct ggcttttggg
     7441 gacttgaatg ttaaccttgc ggaaatcaga ggctaagccg tgtccgacaa acacgcagcc
     7501 taagttgagg agcagccaga gcttcttgta tgccaccttc agcgggacaa ggttatgctg
     7561 gctaaccctt gggtccaggt ccccgggctt aatccctgag tactgagtga cgtaatcgac
     7621 gatattctct tttatggtga tatagtcgtc tatgaaggga acaccttctc ggatccctga
     7681 gcctctgaga acagacaccc tagcaagacc gctcttactg gggcgtacaa tttcctgaga
     7741 gccatccgct ttcacatcga tttctgcttt ctcaagatct acaaactcgg tatcgagagc
     7801 aacaggcgta ccgggggtgg gcttctcctc ttcggagagc gtgacgcgag actctaccgg
     7861 acggccacca ctgagaaagg gaaggttagc gcgaagcact tgctactaga aggagctcaa
     7921 cttactttag cgaccagtca cggaagagaa gagtggtgtc gagcgcgtct ttccaagtat
     7981 catccatagc atgtcgaccg tcttgcacct ggtaggctag cacgcacggt atcttccatg
     8041 gttgattgaa gcggagggct tcttctttgt cgacttccgt aacgaggaag tcgttgaaaa
     8101 gatgccactt gttcttggct tccggttcac gagatgagat ggatacgttt atgaaagaga
     8161 ctagatgtgc cttttggtgc tctggaatat cgatctcaca aaccaaacct accaggtcat
     8221 ataccaccag accgggcatc ttagcttgga ctcgaagttt caagtcttca ccttcgaagc
     8281 ataggatctg accaccttcg atgacgattc caacttcttc cggcaaccac ccaggaattg
     8341 cccaaagccg ccggcagatg gggttggtga gagccgcatt aagcatcagg acctgaggca
     8401 tgcggtgaac tgatttccga atagcaactt gctgatatcg acgacagtag ttgcaccatc
     8461 ctctgttttg cgcttctcgc tcaatgctgg ctcgtaagat atttgagaac cggaaggcag
     8521 gattcctgcg agcttgcttg atatcgatcg caggatagtt cagctcgttg acaagagagt
     8581 ttcccggtct cacaatctcg ttctggcaga acatgcagcg aatggactcg gatgcgaccg
     8641 ttgctagtct gtggtccagg tcgtccgagc tcggcgaaat catacggaag tcgtgcgaaa
     8701 tctgacccag gaaaaatctg ttgacagctt gaatcgcagc cgaaagtgac ttatttgtca
     8761 agttttcttc aaaaagacct aggttggatg cttcgcgata actgctgaag gtcttcagta
     8821 ggttcgttgc ttggcagttt tggccactcg ctttttcgag catatcgaac aggtagccca
     8881 tctcgcagag cagacatgtc tcgaaaatac aagaacttgc ggcatggtgg agagctacgt
     8941 tgcgtatata agggatgaat ttgaaaagtt gaaggagagc gttcgtgaag gaatttgcaa
     9001 tatgtgtttc caaaccagag aacgttgtct gattgtagaa cctattcaaa gcataagttg
     9061 ctgtgtatca ttccacggaa tacgagaaaa cttacctaaa atcgaagtca tcgacaccaa
     9121 acctactgta cttgatctca acattgctgt atttgaggag aggatcatcg tccgtttctc
     9181 cattgatttt ggcacccgcc agagcctcgg cagcgtcact tatagcccct ctgattttgc
     9241 cttattctgc tctcgtgcct tttcactcaa aaacttggga gcaataagag caggctcagc
     9301 agaagccaga gcgcgagtgt tctccacctg ataacgccgt gtcttcttcg gattcggcgc
     9361 atggtgaccg agctctgccg gacggagata agggatcaga gcctgatcta cttgaggagg
     9421 gggactgccg acttcaaaaa ccagatgact cggccacgca gagaaaagac gctcgtgata
     9481 ataaggcatg ccaatcatac ttagaggcgt ttctggagac caatccaggg tagggggacg
     9541 aggagctaca tcgccgaatt ctgcttcttt gctcatctca ttgaaatgaa cctttgctgg
     9601 cgatccccat agatggatgg cacattcggc atcattaatg gctaatgctt ctccggatgg
     9661 tgacaggtcg ataccgagca tgaaggaaac gttcgcctgg cgaaggttga tggcattcgg
     9721 attcatcagg tccacaacct gaagctggcc tgtctgagat gcaacaaaac tcgttgtatg
     9781 caacttcggg tgcatccgta cataggcagc tccggcgtga aagggtatcg ggggtaacgg
     9841 cgaaagggtc ttcaggtcgt acacgttggc caacggatcg acgatggggg aacccagatg
     9901 cctgacagag aagccgcagg taaccaaaag atcattccga gcatccatat cattaactgc
     9961 agtcccgtgt gctttccacg acttcaccac actgaagtcg ttcaggctca gcgcgttgac
    10021 tgagcccgta tctgtcgctg cgcaaaggta tcggctcttc ttcatgattg tgtagttata
    10081 ctcggtatgc agcttgtcta ttataagtcc cttatcaata tcaattgtaa acatcgattt
    10141 ctgacatcct gccactataa tccggttggt ttgggctgtg aagctcatgc agcggagatc
    10201 ggtcatttcc tcatgagcga tgtgccattg tgtcaagccg cgccgtgtta tcatgtgcac
    10261 acttttcggg gagagcgaga taacgcctct gtcatggaaa ataatctgcc gtaccggctc
    10321 cgtcgcagga tgtgcccgga cggaggtata tcgctgaagt tcagggccga agaacgaggt
    10381 gattcgtccc taatggagta cacaaacgct ggtcagcaca gccttcggta ttagctgcaa
    10441 ataatggaaa accgacaaat tcatttccca cccacaacaa ctccatcaca tcatcaaagg
    10501 ctattgcggt tgcgattgtc ggcagggcat gcacgctcgg tgcaggcacc ggaatgcgcg
    10561 acagttcatc ccaatcggcc tccatggcct tgacatcgca cccggcaagg gtgacgagct
    10621 ctagataggg atgagatttg gattatcgcg gagtcaagat gattcaggca aggcgtaggg
    10681 tcagtccatt gggggtcagg gcgaaagcgg gcatcgttcg gcgaaagcgc gagtgcgggg
    10741 agaaggtctg gctggaaaag gcgtggttgt cgaactccgg aacaccaagc acagggggca
    10801 agattcacaa gctggcaccc acacgaacag tcccaggctc tcgtttctgg gagcaacagc
    10861 acacgagaca aatggtctct ggggaagggg taccttccag tcagagctgc cggcaatggc
    10921 tgatgaggta ccgacgcata ttttcacgtg acttcagccc gagcgggaca aacatccagc
    10981 acatcacgcc gttgcttcgt caccgcctac tgcataaacc ctcgtacata tgtatttctt
    11041 gctgagttgc gtgattaact gtattcctga ctattctaat agggttggta tgttcttaat
    11101 tactcgtaaa ctaagttcta tcggctttta ggaattcgac aactaatagt caggactatg
    11161 ctcttgctgc agacaacgga gcacctggat ggctagcaac ttatttatat agccggctcg
    11221 acgggaagat agactactaa ataatgatac tacttgtcat tctgcgttga ctgaagtgta
    11281 tactaagaat aggttagcaa gtggccctcg accatagcag cacgcgaatg aggaaagaag
    11341 gttataaagt aagaggtgcc ttggtattat attatgatag tcaccaaaag atcaggaatt
    11401 agttggactt ttgtgtaaag gatagagaga ttaggggccc agctggcagg ctgaatctta
    11461 caggcgccca tacaagattc atcatccgga gctggggcta caggactatc tctgtgtaga
    11521 aggagtccga ataactctcg tccgcaaggc tctcgagcat gctatatgcg taggcaggga
    11581 tccaagccca gcagcccgct ttattatgaa actagtcgtt catttaccaa ctgcaagagc
    11641 tcagggctct aggagggtat gtagcggatc gccatgataa caaagtgtcc actgtaccaa
    11701 gccaacagac cactgtctac acctctccat atcttcgcat tcgaaccaca cacccttccc
    11761 cacaagaaac gaccaacgta agaacctgcc tctcgtcgcc gactcctttc tccatcctac
    11821 acccctccgc ctgctcaatg acctcgaatg tctgcagcaa ccgcataatg gtgtacccga
    11881 cctctaacaa ggcaaattcg cgtcccagac agacccttgg tcccccgtta aatggcaaat
    11941 accccagcct acatccttca acgcatcgtt ctcccagcgc tcgggtcgaa atttatctgc
    12001 gtcggcgcca tagatatctc tacgccggtg catcgcgtag acgcagtatc ctacggcctc
    12061 gccttttcgg acgaggatcg gtgccgtgcc tgttggtccg ccgcctgtgg ggagggttgt
    12121 ggttttggtg gcggcgcgcg agtttacagg gacggagggg taaaggcgga ggactgggga
    12181 tttagtgagc atcaggagag tgcgattggt ttgggtaatt cgaggttgaa ataccttctt
    12241 tgatgacgag ggagagatac ggaagtgact tgacttggat tatagtaggt gccggcgacc
    12301 taggtccaat cccgactgta tcactgattt cggcccgcaa cttggaaagg acgggaggat
    12361 gctggacaag tagacgtctt gatttgtttc aagtgtcagc ttactcgaaa gaataaacct
    12421 tggtacatcg gcccttacag agtccaagtg aggcaacaag ccgtagtgtc cctcccagct
    12481 aacaggatat tcaggcactg atcccgaagc acttccgggt tccgggtttc ctcgataaag
    12541 gcatcaatga agatgtacgg ctctgtcttg gtgcccggag tcttttttgt agtcaagtcc
    12601 aaggcctttt gtacagcacg gtccacaaat tcatggcagg tcttacacgc ttctcgaaaa
    12661 tccctcccgt ctagaagcca gtagaagccg cccaatcgtc cgcgtttggc caagtactcc
    12721 tgtccaagat tgaaagcgtt cgcgaagtcc gattcctggt ttttgatgcc ctctaattgg
    12781 agagacggca ggtgttgccc aaacagtaga aagagggtag tctcgaacgt gaggcgaaag
    12841 aaaagcggct gtagattgac ggcgttgtca tcagaaatgc tggatatgag attgtctacg
    12901 gcgctgcgta tttgctcaaa gttggtgaac ctgttcgtca tgaactgtgg gcgtagccgc
    12961 tcgcgtgagt gccgccactg tgcaccatcc tgagtgaaga ttccactccc caacaagggg
    13021 cagaaagttg ggggtcgcag tccgagtcca aaatctgaag tttcatttgt cagtggtagc
    13081 aaaaagatcc ggcgttcaag gtccactgac cagcatattg agtcgacaga agagcttgta
    13141 tgttctgagg gtcgatagtg tcgactcctc gggagaaaag gagattttgc tcgaacgttg
    13201 tgccagactc agcaacgaca ccgagaaaga atttgagaat ttgctgccta cggtcatagt
    13261 gaaatgcttg aacgagtaga tccaagccca gcggccaagt agagttccat tgtcttagtg
    13321 gcaagcatcc atttgcggca gcaactttgt tgtttgcctg agatacgagt tagggaacaa
    13381 tgaatctaat gcggacaggg ttgctggaca acgattcata ctcgtagttc tcgcttctgg
    13441 gcaatgaatc tataggcgag tgcgcatatc catgttccca caataaggct gggagccact
    13501 gagttgagaa atgccatgtc gcttgcatga aagtaatctg agtgaaagtg cagtattcca
    13561 gagaatcacg tactgggtat tcaagctctg aagtactcat atatgacctc cccacctact
    13621 ctgtggttgc atcagtaaga tgactcaggg gtagagcgcg tacgcctagg cacttaaggt
    13681 tgcacaaact gtactagtat gagatgatga ctcctggcag cactaccaca agggagagaa
    13741 gtggggttga tgcttgctag acaggaagtc ccaacatagt ttcaccgttc tttatgaaag
    13801 gccgcggccc gcctgccttg ccattgtgtt tacgcgaaac gtcagtggct gattttcaga
    13861 gtcgagagtg tggtacgcgc ttaaagaact ctcgcgaatg tctctgatca cacacattgt
    13921 ggcaaattac agctgctcaa tatattcgtt cgtacacaga cgggctcggg agagccgggc
    13981 atgagcactg cagagcaggc cgtctgggct aatatcgcag cggtagtctc cttccaccgc
    14041 tttgtgaaag tgagaactaa gaaatctttc ggaatgacgt acttgcttct gtagaccaca
    14101 tccaggcctg tcagggagtt aacgaccaga caatccgggc aaatcgaaca cgtcgctggt
    14161 atgggcttac ccagtggctt ggaccggggt cgaggcttgg ccgcgagcaa gcccaacgct
    14221 ctgcaaattt cagcagtgtg cttgctaagt caggatgctg gaaggatgcg gaagtactac
    14281 agttgcctgt gaaaaattat acgccccgcg tcttgggatt tgaccatcct tcaacgcggc
    14341 ggataatctt ggtgttagca cagacctact ggagtcaagg gcatggagac gaggctgcgc
    14401 aattgcaaca gactgtcttg cgggcttgtg tcgcttcgta aggtcccact gcccattaga
    14461 ctctgatggc gaaggatatt ctaggcagac aagatggcaa gaagggcgac acacccatgc
    14521 cagaatgctg caacaatatg ccgttgacgg gctgataaag cccaaggggg ttagacaccg
    14581 aagatacctt gacgggcatg agcagtctcg gtcgtaccat tgccaagttt tatgagaacc
    14641 tggatgaagc aaagccactg ttcaaacggg ctttggatgg actgaggaag gtactcgggc
    14701 caacacagcg aggccgaaac catcctacgc agcagatatt ttattgcaga gcgcaatctc
    14761 ggcgacagcc acatagggtc ccttataggg aaaagtcata ctaggaataa atccttatca
    14821 accaatctaa attttccgag gctggttcaa cacttcttga cgcgatggaa cggctacggc
    14881 atctggcttc ttatagggga gactttcatc cggaccgact cggcgcgttg attgtgcttg
    14941 cgagaagcta taagcttcag ggaaggttta atgcgagcat tcaaaactgc gacgaggcta
    15001 ttgagggctt gaaacagatc agtgtgacgc aatattcgtt agagaggaag ctgcgagccc
    15061 agaaagaaga gacaattgcg atgagagaac aggaaggcca gctttgagcc caattatgcg
    15121 ctttcgctaa aaatgggtga gctcctgtcg cagaggtttc atgattctaa gatctatgtc
    15181 tctaaaccat gaacccttga ttggatcatt tttatggtaa aggcatttag tgcactgctt
    15241 ctgtttcgca agtcggcggt aggctcggag ttttgaatct ctacacgcct aactcagccc
    15301 tagccctcag ccccctccca gctaccaaga attcccagta gagaaacagt aaacagttgt
    15361 actacagcga gtagaatccc atctcgtggc agtttcctgt cacctcaggg atgagctcga
    15421 tgcgtctttc ctattgtacg ctgctattcg atgccgtacc caagcttata taaatagagg
    15481 cttggcgaca tattgtctac taaatctaaa tgtttctgct ggcggccgca gtaatcaatg
    15541 ccgagtgaca ccagcagtgt cctgtgcatc aaacccgagg tcaactggca ataccgaaga
    15601 taagtaatat gatggggaga ggcgagccta atcttgaaat ggctcgtgaa tactagggta
    15661 tagcccgggc tcttaggtcc cactgctaga ctgcctagct ccgcgccata gccccctaac
    15721 agtatggtcc ttcctcggcg ccttgagtac atatgctaca acgccaaaca aatagaacat
    15781 gttcttagaa aatttggcag gtgtcaggaa tttttcatac aataggcagg tttatgcttg
    15841 ttacgtggct tgcattgcag gcgcctgcat ttacagatcg tcgaggaaag gcgggcctca
    15901 taggggccaa gctttgaaag gaaaagcttg gtcaacagat cgcccctggc actaaatgca
    15961 aggaggaatc gcctctgggc tttgaaatta cccggatcat atcttctgag aagccactat
    16021 tggcacacta gttcgttcgt gactgtgccc ttcggtggtc cggcggctgt tttcggagaa
    16081 tatgacgccg cagggaccgc tccaccatct caagtgatga tataatggct acatggtaac
    16141 ccggctacga aggtttgatt tcgcatcaac cgatagtata ttagccaaat gcgcgggcct
    16201 gggactatga aagctgtcct gtgcagcctg gccttcgcgg tcggagttgc ggccaaggat
    16261 gatccagact atgacccatc cctcaatttt cgaccgaaga atgtgaccct cagcatcctc
    16321 gattactggg ttggatcgtg agtttctgga tgacactgag ctgttgcgtt gacgctgact
    16381 gcgcaggtac tataacggca ccacagacgt ggaattatcg ttttacaccg ggctggctgc
    16441 caattggagc cacctgtgcc ccaatctcat caacacaacg gttaccaaaa agtataataa
    16501 ttctgtgctg ggccttacag agcccagctc ctataatgtt ggctatgacc cagtgaatgc
    16561 tttcttcacc atgtggcctc gcaactttaa tttctccact ttacctgacc caaggtggtc
    16621 atgggaatca atacaatatg acgcatcttt gaggttcgct ttgttctcat ctgagtgagt
    16681 gattccaccc aaataagaga tgtcccggct gacaatccct agtcctacat actgggtggg
    16741 gcccagggtg tctaacaact tcaactggac actcaatgca acacaaggcc caccgtacag
    16801 tttatcaagt actctcaccg attatgaccc gcttggggct gggcctccaa cttggccagt
    16861 tgcaacggga gtgacatcgt tgagtggacc ttttacccga ctccctggga tatcatgggg
    16921 aatggacttt acctgcctga tgcggtgctt gatcttcagt ttgatgagaa gactgctaac
    16981 ctctcgttaa atggctactt catcggctat catgcagtta aggtaggtac agagactcta
    17041 agcactgggg tcctcgtagt aggcaagatg aaactatcct tcttgggcgt cttggatgcc
    17101 tatcattcag atgtcctggc caataacacc gctacgccga cttggctgcg cactgtgggt
    17161 ttccaaaata attctttgaa tgttggatac actagcacag caagcagtgt atcgatggga
    17221 agagcggttt ttgctactat cattgctttg acagtaatgg ctggatttgt ctagacgaga
    17281 gctatccctc tggcagcttc gtcgcggtta taaaggctct tgatcgtgta cagcaactgg
    17341 aggattatct tgtcgacatg gacggatttt ggtttaatat gtattgatag atatggaagg
    17401 gataagtttt gagtcatcga gtataagggt ctgctccagc gatacggtta gattgtggta
    17461 catacaatag tttagaccga tgaagtggta ctgaatatct tgctactact cgagtgctcc
    17521 agcttaatac ggctgcatgg gagacaagat gctgcatgcg aatgcaacaa gtgataaaga
    17581 ctacaatatg ttgctactag ccaacataaa gataatctac gtatattttt gaacatactt
    17641 gcagcaataa ctgcacaaga gtattagcta gataggagca agtcatgacc cagatttagg
    17701 ccaggatcac gtactctcga attatagaga gacgataata aagatatcag atagagactc
    17761 caactacact ttgttcaagt caacgaaaag ggcaatagag taagttaatc tactcaaaat
    17821 cgaaagataa cacttagact ctaagccttg tatattgctt actatttatc tttcgtaatt
    17881 ctcttgtaag ttatctgcgg ctttgtatca gttcttgttc atttatccca acatgttata
    17941 ggtggctcag ctaacattag agccacactc ctgctttcaa aagtggagta tctgtctact
    18001 agctggcatg tcatagagtt ggttcaactg gtcagacacc gtgaaatgac tttcggattg
    18061 aacgggcctt aaaccatagt attggacctt cctatccgag ataaatgtga gttcagttga
    18121 tacctggctc ttcttctttc actttcttat cttcttcctc tgctcccctc cggccagcgg
    18181 aagtctgagg tcaatctgag caacatcgga gataagtgac tattgcgaat tagtccaagg
    18241 gtccggctat gcccgggctc tggggcccca ctgctagact gtctagctcc gcgccacagc
    18301 ccctattgat tttctctgat cccttggtgg tggaatgaat acattcgccg tggaggcatt
    18361 ttgttgtata tagaattata gtaggtctct tgtaaaacag acagttcgtt atacttgatc
    18421 ctgggtggaa tgtcagcctg catttacgga tcgccaaata gagggagcct cataggagtc
    18481 aaacatgaag ggtggaaatg gggtcaatgg atcattgctg acactaaaac actagaaaag
    18541 atcgctttgg cgcactggat tacccggaca aacacccctc cagtagacca ctataggtgg
    18601 tctgattcgt ccctactgta ctactcggtg gtcccgacgg ctaatcatcg gggaaaatgt
    18661 tgatagcgca tcaccatcgt ttctactcta tcgctcactt attgatttgc tgatttttga
    18721 aagcctgatc tatgattatg ttatgctgag aagcctgcgt aggtaaacac atcacctgac
    18781 ctcatgccgt tgttatccta cgctttacct tcctttctca tggcttttag acttgacgcg
    18841 ccgcctgcat cacaccatca acaaaccgat attccatgac atgttgcttt cgggatccgg
    18901 cccaatgaga gaagtatagc ctcggaataa tgctaaactc gcagctcagg aatccagtcg
    18961 ctccactgtc gcaaccacac tttcatcagc gatgcatcca ccggacccaa cgctcgcaaa
    19021 gctgcactat gcttctgagc attggtggtg tccgcaggag gacgtatcta accctcagat
    19081 tcagctagtg acgtgaagaa tcctagcagc gatgccgcag gaattttccg catgacctcc
    19141 tcgttgagat tcgggtcaga tagccggttc gtgaggtttt tcacccatac cctgagcgga
    19201 ataatcttgg tggaacaggc ttggctgata atctgtgcca atggctccca gtggctaata
    19261 tgtgggtttg tgatatgata gacctctgca tggttcgact ctgtggaagc tagtcgacca
    19321 ctatgtctcc cgcagccgat ttggacaatg ctccgagcag caacatccta cagaattagt
    19381 acactacaga tttcctagga acatattcgg gaagtggctc acatacaatg ggcacccaat
    19441 ccactgggat tgaaccaata ctgtcaggca gctctttcat cgtctgagat gttcgtacaa
    19501 gtgccggaaa ccagtctcgt gtcgtccaca ttccggcctc agcatctgca ggtcctccca
    19561 actgaccaac acgatgaata gcaatcgtct gttgagtttc tcccgcgacg aggtcacaga
    19621 gaacttctgc tgcgtatttc gattctgcgt agccttgact cagtactgtt gacggtccat
    19681 acagtgtttc tgcaatgtga tcagtttcag gcaggatggt agagcgacca ctaacggccg
    19741 cgatggaaga aatgaaatgg aatgctgcct gacgtggtga gtccttgatt aggttgagaa
    19801 gccgtcccgt cccttccagt tgagaacgga agctggacaa tggcagattg aaattcacca
    19861 tccacgcatt atggaatata atatccactc gctcccgcaa gtaactatat tcctcttcag
    19921 ttagcccgag cctttcctgg ctcaggtcag cctgccagaa tttgactcga gaagtttcaa
    19981 cgagccagcc atcagctaac cgcttttcac ggaatctagc gagctgtcgg gtttccgcat
    20041 ctgccgaacg attgaggcaa tatacatgtg tgatggtcgg atcctgcagc agctcctcca
    20101 agagataact gccaagttcg ccagtcgaac cggtcagaag gaccgtcttt ccgcggagct
    20161 gaaggctctg tgcctgctgc cagattgcgt gtgtcaattg atgctctcgt gaccaaaagc
    20221 tcactgcgtg tttctcgcct tccgctccaa gatgaccacc tagttgtcga aacagcgtac
    20281 ttgcgaggcg ccggaccgtc gcttgctcat agatggctgc actagtccac aagatagata
    20341 tttgcttggt ttgactcatg cgatcggccg catcttgcag tacctgggcg agtcgaacta
    20401 cctgaaggga atccatccct agagtgacaa tgtccacatc tagatccaca gtaatgccac
    20461 ccaagatccg agaaaccgtc tcttgtagcc actgctcaat gccttccata gtcgactctt
    20521 gcaatttttc cacgtcgcgg gtagagcctt cgtaccctgt tgcatcacta tataatgcat
    20581 tgataacatc ctcatagagc tgagctgttt ctcgccggcg aagggacccc ttaggggcca
    20641 gcgcaaatgg ccgatcacaa gaggcaattg cgacacgatt atgatggatt tgtccgtgag
    20701 caggcaacaa gccattggca tccttcatga ggggctccag agcctgcttc agccattgtg
    20761 gggtccatgt ctccgggagc tcatcccatt taggttggac cagcaaagcc acttggaatc
    20821 gatcctggcc gaaaatggca gcgcgatgga ctaaggaatg ggactcaaga tggtgctcgg
    20881 catcaatagg gttgagcttt tcgccgttgc ttagaacaat tatgtcatct gccctcccct
    20941 ttgaccgcca taggtgcggt tttgttggat gaggttcaaa aagatcaccc gttcgatatt
    21001 cgctaagatg tggaaaggcg tgaaatatgc catgataccg acgggacgaa ggtcgaggga
    21061 tgaccaactc ccacagtcca tcaccgactt cctccatgcg atgttcgaag gcgggattcc
    21121 attcgaagca tgcccaatcc gcggggtctt cacaaagaag tgttggtgtg taaccggtct
    21181 cactgctacc catcaatgtc tgcaggcgaa aatgggatga aattgcgttc cccgtggcgc
    21241 ttgacagtgg tgcgccacca aagttcacgg cagacaagcc ctgcagtgcc tgtcgtccct
    21301 tttcagacga ccaaagatcc tgcaacgcaa atggagcgat taaacaccat cgaggtgggt
    21361 tgggagtcgc cataatccgt gagaagagat ccggggttag aggccgatct ggggacagca
    21421 aaaaaggtgt ctcataaaat atgcattcac aaacgcatac tatgccaata aagtggaata
    21481 atggtccgtg gctgaatcgc atctcacctt tatgtcgcag aaacaactgg gcggattcac
    21541 gaccctgggg cacgggaaga gtttgcatct gatctagcgt tgctagatac ccatgggtaa
    21601 gagttaccgg tttggggaga cccgtagtcc ccgagctgtg gattatgata gctggacggt
    21661 cttctatatc tgcgaaattc tcttgatggg gatatgatgt gacaggagat gctgcaaaga
    21721 catccccaac gggatccatg cgccatcgtt gtaacccgag atcagaacaa gcgatttcaa
    21781 cctggtcgac aactttcttt agctggggtc gctcgctacc atccacaagc actgagcagc
    21841 tcgtttttaa cagcaaatga tgaaaggctg cctgtgagtt gcgagtggat aaaagtaacg
    21901 cctaagccta tcagtcagaa acaagcatcg atactgtgaa acaggcatcc ccaactagga
    21961 atgtgagaag gtcataccgc atggcctgtt ttcatgcaag ctagctcaaa taccaagtat
    22021 cgcaagtcat ttgttccgat ataggcaaga acctgctgct ttcttccaga aagcctgctg
    22081 tcaatccacc atgatacacg gttcacagcc gcagacagct gctggaacgt tatacaacgc
    22141 cattcacaat cggcatcctg ggagctggga tgcaaacagt acaagcgatc aggctgatcc
    22201 ttcgcttgtt gatctaccag ctgagttaaa agccgtcctg aactatcagc ggagcccatg
    22261 ttgctgtcta tacaatcctc tgatgctgct aatgggtttt ttgcaaaaga gacgttttag
    22321 actaatttat atattatact accccactcc atcattccgc agggaaaacc acagatacgt
    22381 tacttacatc aaccgtggta tagactcgat gatcgccaaa ttcagatggc tgcagccttc
    22441 atcccttgca gtacgagtaa cgttctcgct acactctgca gatctgccct atcctgcaat
    22501 tgcagtggag atcctgtaga cctgcatata gaaggcatgt ctgacgtcaa ggactttcct
    22561 ttctcgactt cttgcgactt gctccagccg tctataacag gcaacgctgg catagcatac
    22621 atgtacgcaa gctggtgtca ccagggcaac ttttaaaggg gccaacgcta actccgtgat
    22681 aactacgatg agaagttata ggattacgtc acgataagca cagtgcaatc gcacctcgat
    22741 tattcttatg cgaataccag gcggtaggta gatgggtgaa cgacgcatta gagtaatggt
    22801 aactggctct tcgccacaac ccattccacg gcagacagca tttgctttag ctctggccct
    22861 gatcgtggaa tgtcatgacc agccgaatgt atgattggcc tccgagtatt cgaatcacaa
    22921 agacactcga cgaggaggcc acaatcgtcc agacctggca catcgttctt tccacgcagg
    22981 tggagagaag gaattgatat acgagtcggt actacatttg ggtgcagggc acatgggata
    23041 agctcaagcg ggcggtcgag gaagaaaggc accgactcgc gtgttataga gtgggttccc
    23101 ttgatgactt taaccaaact ctcggtcaca gagcgaacag gttccggaag ctgtgcaatc
    23161 tctttatcct ttccggagcg gaggctttgc tggtccgctg acgagagagt tccgagtaca
    23221 gaccgacaat aagcttcatc cgcggcgcac ggaatcgtgg gcgaatagaa gattgcgaaa
    23281 cgaaatggtg ggggctcgtc tgggtatgcc gttttgtgct cgagcaggaa cgaaaccgag
    23341 attgcagctc cttgactgaa ccccaaaact ccgtcaaaag ggccatgctc atcaatagcc
    23401 tcttcgatca aggcatgggc agcatcgatt gaccctgcgt caaacgaccg cgtccagcag
    23461 tagtatggag gtgggaaagt gctcccaata tctatattcg gttgatgaag ctgatgttta
    23521 gcaacaactg atttgcgata aatgactgac aaacatacct ggagcaggcg gacattcaac
    23581 ttcagctgag agaaaatgaa actcccagct tgggtcagca tctcgcatca accccgaaag
    23641 ttgatatcgc agaatattag gccccgtgcc gtagccatgt aggcagagga ttttcattct
    23701 gattgctgct tttggtacgg tattttacca gtagaagatg cgattggata cggttggaca
    23761 ggccagcaag gctgtttcga atcgcatcac tttgctcacc ctaccaatgg attttatagg
    23821 gctccaagac actcttgtca ggctttatga ccaaacaacc agtaccatgg cagaaataat
    23881 catactttgt aagttaatta cataacaagg atgtccttgc agaggctgac gttctctatg
    23941 atgtgggtat cggggtcagc atcctagatg cctggtccat tttcatggga agtatgcagg
    24001 aagaccatac tgttcacaaa tcataggcaa accatgtttg aagagaagtt acagcgacac
    24061 taaatcatcg tttcacgacg ccaggtggtg acacaaacgt tgtcgatcac agccgcatga
    24121 ccatgactcg cccacggata ttatcgactg aattagtggc attccaacaa cctactgatg
    24181 atggtaaagg gccattgagg aggcaagtga gccggtgagt taccactaga cgaacattat
    24241 cttgccgttc tgcccaaact ctgtgacgtt gctgatacag caagccaata catctatcca
    24301 tttaagttct attatcttcc tgacaagggc gctcacgggc acttggccct tgcgtgcgat
    24361 ctccacttgt tggaattctg atgaaaaacc tccggcggat cttattgggc taatatctgt
    24421 acagtctgca tagcagctca aatcattcaa tgatatcgca gtatatctac gtggcgatcg
    24481 cgaaggacat caggaaaggt acaaatctgg agatactatt cctgtctgat ggatggaccc
    24541 gctgttgctg agtccactcg gcttgatcca ctcttcaaaa ccccttgtac aacctcgaat
    24601 actgaaaagg taggtggttg acctcatggc taacctggaa tttccagcct cgcagtttcg
    24661 agagtctcat cgacaatata caccaactta gaggcccgca ccttgccttt ccgcagccaa
    24721 tccaaccccg aagtaacgcc agccagactt ccaggcttga cctggaaccg aggagaagcg
    24781 atttggcggg tctgcaggag aatttcaacg gcattcaccc attgagcccc gaacgagagg
    24841 ttctctagct gagcctggac ttctttgccc cccatcagat acggctcccc aatcatatca
    24901 tatgccatgg aaacatgagt atcaacgtcg cctcgaggac agcgtacgtc cagtagtgca
    24961 ttgtaacagc ccccggagga tgaaagggca gcagcacata tagcagccga ctgattagtg
    25021 gagattgtat cgaaagctag ctcaagggta tcatcggtaa cctcgcggat ttggtcacct
    25081 acatgaggat cgtgatagtc gaggacgata tccgcaccca gttcatgcat ccaggcacga
    25141 ttaacttctg agcacgttgt gacgacgcgc agccccgata gctttgcaaa ttggattgcg
    25201 agagagcctg tcgaggttgc accaccgtag atcaggatgc tagggatatc ctcatcatta
    25261 cccttctcgt ctctctgcag atccgtgatc ttatcatcgc ataccattcc agggtcagtc
    25321 agctgcatgg actggtacag attctgaccg atagtcatca tgccgacgcc caagcaagcg
    25381 gctctgtcaa tgtccatcca ttccggcacc ctgaattgta tgtccccttt cgcgatgaca
    25441 tactgcgcaa atgcacctcc ctgaggctgc atcacgttac acccgtgtac aaagccggca
    25501 acacggtccc ccttcttcca aggcttcgtg actcgtggtc cgatggcctc gacgacgccg
    25561 gcgtagtcac agccgacgac tgttcctgcg caggagtcga agtcaacgtg tttccagtcc
    25621 gttgggttta aagccactat gtttcttatc aacttgcgcc cagatactag agatctattt
    25681 cacacttacc tgcttgcgtc ttcaccaaaa tatagtcatc aggcagggcg ggtattggca
    25741 catcatcggc caaagtaact tgaccacgct ctcggacaat gacagcgcgc tgaacaccca
    25801 tgattcttgt gtctagtgag tgctaacctg caagtgtaaa ctcaaatcac tattgatagt
    25861 ggtatagaac gtatcagacc cttgatatga attcgagacc cagctactga gggcaccagt
    25921 cagcagcctt accacttcta tatagcaaca gattttgtgg atccgcttga cgcgatgacg
    25981 agatagtctg tcaaggaatt gcctcaatag aaaacgacta aaaccagtcc tgatccagca
    26041 acgacgatca aacatagttc aagaactcaa ggataaatct ggaccacaac tagatagcag
    26101 tccttgcgtc atatgtcgtt caattactct tcttgggctc ccgcattaca tgcctgaatg
    26161 tttgatgccg cggccgttct aacagcagtt agctataacg tcacttttcg aagtcaaatc
    26221 tcattatgag agtattttat tatatatcga agctgttaaa ggacccaggc cgagagctag
    26281 agccagggtt attctaagga aagccaggga aacggtttta ttcaattaaa gtcagattga
    26341 acaagctatc ttatgacatc agtcacaatg gaagagcacg tcagagacac ttctggccca
    26401 gagccaattg cgatcattgg catgggctgt cgctttgcag gcgaagcatc ttctgttgaa
    26461 ggattctggg acatgctgcg cctgggccga agagagcatg ggcgtgttcc tgctagtcgc
    26521 tatcaagcct cagcctggga acatcccagt cacgagcgca aaggggctgt atgttctgca
    26581 ttgattttga ccgcttcagg atgaaactaa ccacgaggtt atgatgtatc attagatcaa
    26641 tcacgacagt ggcttctttc tagccgagga tccatcccac tttgatgcgc ccttcttttc
    26701 cataacgtcc aaagaagctg caggtatgga tcctgttcag cgtattttgc ttgaagtggc
    26761 gtatgaagcc tttgaaaatg gtaagtaagt tctgcacaga gtcgcaggga atgaatggct
    26821 gagtcatgat cccaggcggc gttccgatgg aaaccctccc cggtagtgca accggcgtct
    26881 atagcggatg catgaccaat gactacgagc tgctttcaac ccgagatatc atggacatgc
    26941 cacataactc ggccacgggt aatgggaaaa ctatgctggc taaccgactt tcatggttct
    27001 tcgatctccg tggtcccagt atcatgatgg acacagcctg ttcgtctagc ttgacggcgc
    27061 tgcatctggc tacccaggca ctacgggcgg gcgaatgtag ccaggtaagt gagctgtcat
    27121 atgcgatctg atgatgatga ctgattattg taggcgctgg tgaccggagc aagcctgata
    27181 ttgcatccaa actttactca gcggctgtcg tacatgcata tgctcagcgc tgatggtatc
    27241 agtcactctt ttgatagcaa agctaatggg tacggtaggg gtgagggatt cggtgcaatc
    27301 ttactcaaac ccttgtccaa ggccatggca gacggtgaca tgattagagc aatcgttcgc
    27361 gctactggct ctaatcagga tggacgtacc ccgggaatca ccatgccgaa tgcaaccgcc
    27421 caggctgatt tgatcaggtc aacctattct cgagctggat tgtcgatggg agaaacctca
    27481 tactttgaag cccatgggac tgggacagct attggtgtta gtataagact cattgtttca
    27541 tgacaaggta ctaacaacgt cacgtaggat cctaccgaat tgtctgccat tggtgcaagc
    27601 tttggagccg agcgaaagcc aggtgacgag ccactttgcg ttggatccgt caaaagtaac
    27661 ctaggacata ccgagggtgc tgctggcgtg gccagtatta tcaaggtggt tctttgctta
    27721 gaaaaaggga tgctggttcc taacgcaggc ttctcgaacc tgaaccctaa gatccgactg
    27781 gaggaatggg gcttgcgctt aagcaacagc accacaccgt ggccatctca tttgctgcaa
    27841 cgtgcgagca tcaactcatt tggctttggt ggtgccaacg cacacgccat tctcgagagc
    27901 acagctcagt accttggtaa gacgcaagct ccgtccgact ctaccataga aggaacaccc
    27961 caggttgttg tggtatccac gcatgaccag tctgggttag accgtacggc cgacaaatgg
    28021 acgagtttcc ttaatccgtg cgtcgatggt aaaagaaaag acattgcctt gttagatgta
    28081 gcacacacta tggctacacg gcgatcccag cttccgttcc gcagctttgc tgtggtgaac
    28141 tcactagcag agctgcgaaa tgtgatggcc gcaggcttgc ccactttctc tcgggcgagc
    28201 cgtaagaacc aggcgcatct agcattcatt ttcacgggcc aaggtgctca atggccacgc
    28261 atgggtgttc agctactggc aaacccagtg tttgcggcca gtatggaacg aagtcagcag
    28321 gtgctgcaga gcttggactg ctcgtgggat ttgctcgagg agatccgcgc aggggcgaca
    28381 acaagccgta tcaatcgacc cgatcgcagt cagccttctt gctgtgcttt acaggtggca
    28441 ttggtagaca tgctccgcag ctggggggta actcctaagg cagtagtggg ccattccagt
    28501 ggtgaagtcg gtatgtctct ctcgattcgt ccaactcttg tccaagaaat gactgatatg
    28561 tgtcccaggg gccgcctatg cggccggcta tcttacacat gaggatgcca ttcgaatcac
    28621 gtatttccgt ggcgtgctgt ctcaacggat tgctgagagt gaaagccgcg gcggtatgct
    28681 cgctgccggc atctccgccg ctgatgcgca ggaatatttg cagaccttac ccccggagtc
    28741 cgcggtggta gcctgtgtga acagcccatc gagtgtcact ctttcaggca atatagaaga
    28801 aattaacctg cttgagaagc gcttgcaagc ggatggctgt tttgcgcgca agctgcgcgt
    28861 agacactgct taccactcac cgcatatgag agcgttggct gatgactata agacagccat
    28921 tgaatccatt cagccagttg acaagtacaa tggctctata tctatgttct catctgtcac
    28981 aaaagagctc ttgcaggcag cggatctgga cgcgtcatac tgggtgcgca acctcgttag
    29041 cccagtcgag tttgccgctg cagtcaccaa agttgctacc atgactgagg ctggcagggg
    29101 gcgagggaga cgacgagtgg tcccagtcaa atgggcaggc tttttggaga ttggcccaca
    29161 cgaagctctt aaagggccgt tcaaccagac cctgcaggaa gccaatgctg atttggcttc
    29221 cactccttac aagagtctgg tgctccgcaa gcaggattct cgacagacag ccctccaagt
    29281 tgccgggctc ctgtggtgtt tgggctatgc aatcaaccta gatacagcaa atcaaagctt
    29341 tctggagagc agaaggccac aggtgagccg agaccttcca tcttatgcct ggaatcatca
    29401 gtccaccttc tggcacgagc cattggaatc agcccggctg cgacagcgca aagaaccccg
    29461 tcacgacctc ctcggtatgc cttgggacta ccagaacgag ctggagccgc ggtggcgtaa
    29521 cttcctgcgg gtgtcggaac tgccctggct tgcggaccat gtggtggctg gctccattgt
    29581 ctatccagca gcaggcatgg tgtccatggt cgcagaggca gcccgtcagc ttgcaggcac
    29641 tacgaagtgg ctagagggga tcgaatttaa cgatctggac tttttccggg gagttgtaat
    29701 tcctccagac gaacggggtc tggaaatagt tctccatgtc gcgccgcatc acggcatgaa
    29761 tggatggtac gaattcggca tcttctcctt gcccgagaac tcctcctggg ttcagcatgc
    29821 gaaaggtgct tttgctccac aatatgctga tgaggatgga gttggatgtg ctgcagactg
    29881 gcaatgcact gtacaacggg ttcgacagac gcaagctatg gcaaagaagg ctgagattga
    29941 ggccgtctat gaatggctgt cagaaacggg cggcgtcact ctggggccga ccttccggtc
    30001 catggctggt gtagcttttg actcggagtc tcgtctgtac gttactggag ttgcaccgaa
    30061 cactaagcag acgatgccat atgagcgtga atctccatgt cttgtccatc ccacctctct
    30121 ggacagtcta ttccaggcgg ctgtggtgtc atgctcagat gccctgtcca atcacaatgc
    30181 caatatcccc gtgggagtag agcgccttta tctctccacg gccttctcct tgcagcctgg
    30241 tgatcgattc gatgtccatg tcgagacacg ctatgagaac ggcgtgtcat tcacggagtc
    30301 gatcgcttcg gacccatcct ggcagcagcc tggaatggtt ctgcaagggg tgcgattagg
    30361 tcgcgtgccc acgcggtccg gcggctcgac catagaggag atccagcaaa gccgattctc
    30421 gacgcttcat tgggctgagc acgtggattc ttccggtggt ctagaaggcc gttgctctgg
    30481 tggtctgcag aactggcttg gccgggtctg ccacactcat ggagatgctc gtgtccttgt
    30541 ggtgactacc aaagacatag gtcaggtggt tgaagctctc agagactatg cgccgaaacg
    30601 cagtcatcga cctcgactcc aaaagctcac cattgtgcta tctgaccctg acacagaggc
    30661 attaacgaac caggttaaaa tcattaaaga ttccctagat gggtgtcagg ttctaccagt
    30721 tgcctcattg caggatatag gcacggactt gctgggcgaa accgcctatg atgcgatcat
    30781 tgttgatcat cccgatgtct ggagtggaga caatacaaaa gcatttttca actctttgct
    30841 ttcgattact aggcctgatt cttggattgc cgctcgagcg actgctgaaa accacgatgc
    30901 ggccattcgc aatgcgggcc atgcggactg ggaagtacag ggctcgattg aacagcccgg
    30961 ctatcttctc atccgccgtc aacttgctcc ggttgagttg gatcccacta tctatatact
    31021 aagcagcgct gcggctgagt cggtcggtcc tctcttgtat gagctggatg gcgtcgtaaa
    31081 caaactcggt tctaagattg agctggtgga tgtcgataaa gctcccgatc tgaaggagaa
    31141 aatgatcatc tcactgctcg agctagatcg tccatggaca gtgaattgga cgcccgatga
    31201 gatatcacgc tttcagtcgc tgttacaggc aaaatgtctc ctctggattt cacagtgccc
    31261 ggggcatgag gcgtccggct atgcaggctt cggggctacg actggacttt tgcggaccgt
    31321 acgcaatgaa aatccccata tcgtgctgcc tcaattactt gtgtccggaa aggataagga
    31381 tcctcacaat ttggcgcgca gtatcgcaca cgtgttgcag ctaacattga aacctcggtc
    31441 acggccacac gacttggagt tctatatgca agacaatcgt ctgcttgtgc cgcgggctat
    31501 cacggctcgt gcagtagatg agagcatgga tgctctctta cgtggcccgc gccctacgct
    31561 agcagagctc gcgcaggact cgagaccgct gcgcctctgc actaagtcgc aggatatcag
    31621 tgacgcccgg tgggagctgg atgaacggtt gaattcggcc ttgcccgatg atttagttga
    31681 ggtgcagcta cataaggtgt ccatctctga gctagccagt aagagcggta tctctccgga
    31741 ggcgcgtata gcggccatag aagcagtcgg aattgttcgc caggttggaa tgtctatcgg
    31801 ctcagcattc caagtgggag acgaagtctt gtgtgccata cccagtgatg cgtggcccag
    31861 tgctttaacc acccatgttc gcctcccagc aagtgctatc tggaattcgc catcacagca
    31921 gagcgagaca caatcagtgt ccatgccggt ggcttttgca gctgcctaca ccagcctctt
    31981 cggcagctcc ggagcttctg cttcatctgt tctcatagtt ggctccgtta gccagaccct
    32041 gcgagccacg gttgactgtg ctctggctgc gggtatgcag gtgtacgtgg cggtcgatgg
    32101 cgaggatggg attaatggga tgcgctctaa atatgtagga ttgcatgaga gaatcattcc
    32161 tattcacagg gagcttgata caacagtcaa acggctgact gggggcaaag gagtggagct
    32221 gagcgtttgc tgtctaggag gttcggtcag tcgacttgca gcgcgttgct tggcctacag
    32281 cggccggttg gtcgacctca gtgaagagct gaacctagct gccctgcctc agacattcgt
    32341 tgaccgtggg tgcactgtca gctccgtacg gttatcaagg atgctccgcg aagccccccg
    32401 tcagctgcag gccaacttcc atcgcgcagt ggatcttctc ggatcagacg ccctcgccag
    32461 cgttcaggct tatcaatcct tccctgtttc tcaggttgca gatgccgttg ctcatgcgcg
    32521 agacagcggt acccgtgcga ttgtcgatct ccaggctccg ggtcaggtgc caattgtgcc
    32581 agccctccca gatcctgccc ctctccctgc ggagaatacc tacatcctgg tcggtggact
    32641 gggcactctg ggattgcact agccagtacg cttgttgact gcggggcccg tcatttggtc
    32701 ttcttgagcc gttctggggc tgttcgggag acacagcaaa ctgcgctaaa agagcttcaa
    32761 gaccgaggtg cgcgtactga tgtcgtgcgc tgtgacgcgg cctgtcaaga ggatgtgaaa
    32821 agtctgttga cccgagctga aaataatcgc tggcgtgttc gtggtatcgt gcaatgtgca
    32881 actgttttaa aggtaagtca gttcgcagcc cagtagcgtc accaagctaa atttcacctt
    32941 accaggacgg catgttcgag cacatggact tcgacgcgtg gaagcaatcc accgagccaa
    33001 aagtccaggg gacatggaac ctccataaag cgttttactc caccccgcta gacttctttg
    33061 tgactctgtc atccatagcc agcataaccg gaaacatggg ccaggccaac tacgcagccg
    33121 gcaacgggta catggacgct ctgatgatct ggcgacgcaa gcaccaccta ccaggacata
    33181 gcatcaacat cggcctagtc ccagatgcca gcggagtgag cgacgtagcc gaaacacccg
    33241 agcagcgacg ccagcgatac cgacatctag agggtacaga gattctgcag cgtgaggttc
    33301 aaactctgct gcgcgtgata gtccagaaaa tcacccgagt cccagcacaa gtcatcgccg
    33361 gcctgacgga caccctgccg cgaaccgatg gggcagcttc ctggcaattc gatcgcaagt
    33421 tcgatcaccg gattcaagtt gttgctgatg aggatgcagc agctggcgtg gttaagacca
    33481 gcacgttgct gaagaaggcg cagtcggtgg atgaggcggt acgcgttgtg aatcaggcac
    33541 tgcaggagta tttggccaga gcgatggcgt cgtcggcgga ggctattgat ttggagttgc
    33601 ctttttcggc gttaggtggt gagtattttg actatacctt aaattgtttc aggattatgc
    33661 tgacgcttgg ggttttaagt tgactcgctc aaagccgcgg aggtacagaa ctgggtcagt
    33721 cgcgagatgg gcgcggaatt gtcctcgttt gagtttatcg gggcacagcc ggtgagggtg
    33781 ttggcggaga agattgcgac gttgagttcg tttgttgttg ctacgtagtt tgcatcgctt
    33841 aaggttggtt tcttcgttat atgtcgggta gaccaggtta attagtatcg tattattgct
    33901 attaaacacc ataagaaaac aaagtattta ccaatcatta tatattatgt aagtccatca
    33961 ccagtctact tctcccccct catcatcttc gccaactgcg tagtcgcagc ccggcgctta
    34021 ttcacgatat ccaagaacac ttctgcaggc ccaagacttc ccacaacgat ttggtccttt
    34081 ccgtccagta gtccctgaaa tgcttcagcc gtaaattcct tcaggggcat accgacttta
    34141 cggccctctt cgcccatata atcgtggagt tcggctgcag tgatagttag tcagatagga
    34201 aatatatatc taggacaact agatgaacga gacggcagta gaagcagaga attgggggtt
    34261 tagactcaca ttgcaccgct ggcggcgaca cctcaataat cttcacagag cttttacgca
    34321 gctgatcccg cagacagaga atgaaggcgt tcagggcagc cttggaggca gagtatgcgg
    34381 gcatccaggt cgcagggact atggagaggt tggatgtggt gctgttttat ggttagtaca
    34441 ttttagtgca ttctggtagt gtaacctgaa agagatgaag aggtacgcac taaatcaagc
    34501 tcgtatggcc cccttccttg gtaagataag gcaagaaagc atgcgtcaga gcaacataac
    34561 tggtgaagtt gacgtgcatt tgcttgtaga agctgggtag gtcgaatttt tcgggatcgg
    34621 tcatgtcggt aggaagcatt atgccggcgt tcataaagac gctgtcgatt gtggggtatg
    34681 tggtcattat tctattgaag atattctcat tagccatcca ttcaatctag atgcggtact
    34741 gcatagtata tcaagggagc gaaacttact cagcagcaaa cccaggaatc ttatccaagt
    34801 cactaatatc gaattgcacc gcattggcct tgtcttctcc gtgttcttgc aagaattcat
    34861 ccaagcgctc tttgcgtcgt ccgacgactg tgactttgac ttcggattgc acgaagcgcg
    34921 atgcgagagc tcggccgatg ccggcggtgg cgccgaggac gaggatgtgc ttgtatggga
    34981 aggacattct gcttcaaact gaattggatt ggattgagtt cagctgagta tgtattgtat
    35041 atgttggact gagttcagtt gagtttgaat tggattgagt atgttgaact ggtcatcata
    35101 actcttatat actttgatag accggtttcc atcattgctc cactgggaat agtggtgatt
    35161 ggcaggaccg gacagcggag atggtgggcc gaagtcgatc tccggggatt tagtgtgtgt
    35221 ggttgtcggc ttccgaacct aaagccggca tggacggact tcgtcggctt tctgaaatag
    35281 cttcgtctgg ggtcggtcgg agatcagagt ataatatgaa ggattgcgga gatatttaat
    35341 gttgcataaa tatgcagtga ttatgattat aaacaataaa catagttgtg cgcaagacgt
    35401 gatcaccact actgtcaaca ccgtcgactt gtatacagag ctgcagttat acttcaagta
    35461 accctatgcc gagacctccg ttataagata ttcattccag cacactctac actacttgaa
    35521 acccgtgtct cactccaatt ttcgtaaaat gttcaaactc acacagctac ttaacacagc
    35581 acatgccccc tgtagccaaa tcccctcata gtaaagagca gccatcacgt ggcgtagtgc
    35641 catctgcgtg aataaaaaaa tcactgatgt cccagaagag gcaacgcgtc tcgcttgtag
    35701 acgcgttgta tagaacaggt aatgagggca ttattctttc tcgcacaaac acagcttctt
    35761 cttcttcttc ttctacaagg tgaagttcct gatcatctca tctctcatct tattcctcat
    35821 ctctcatccg catacgcttc catcaaaaac tatctatcta tccatcgctg gtatacagat
    35881 agtcaatcat catggatagt gcattcccga agcgtccctc cttcgtgaga tacggaccat
    35941 acacctacga tgactacgga gtcaccgtag ccaacatccc cagagcatca tcccagacgc
    36001 tggcaacact cttccccacg aatccggtca ctgcacccag cagaaggccc gtgaagcggt
    36061 ggatagcggc ccagctccaa cacttcggca ttccctatca gccatctaat actatagctc
    36121 agctgctggc tctccttgaa agagagtaca aagacggaaa ggtaacactc ctccaccctc
    36181 tcagttccag acaaaaagct gaccaaagac gaacagtgca gctacgagtc gccttcagtc
    36241 cgcctcctcg acaaaaccat gtacgaaatg tacaatgccg tgcaggaggc ctatcagcag
    36301 caaaaggctg agtggcggaa gaagaagttc gctcgtcagg tctctccttc cgacgaagct
    36361 ctgttcgatc cttttctttt tatggccaag tacttcctcg acaaggagaa cggagtgccg
    36421 gataaaacca agcagacaga ggccattgtc ttgcacaatg tttataacca gcagttcgtg
    36481 agcacggctc tctccatccc cggtctgagc ttccacatca gccacccggc caccgtcatc
    36541 ggatgggcag acaccttcga agaaggcttg gatgcaggct tcgccagtct gtcacagaac
    36601 cacgtcaagg aatatgtgcc gacctttgag gcgaactttg atcactgccg cttcctgacc
    36661 aagtatttcc tgtcgcttga ctatccctat gaaatgggtg tccctgcccg tgacagaacc
    36721 gtggagcccg tgcagcttat gccccagctg tatttcgacg tgcgcgagaa actcagaaag
    36781 gaagtggcca atatcaacgg tcttttgatc gctactaccc ccggtcgagg cggtacctgg
    36841 acacttatta cctggagcga gtacgcagac aagctcaccg gtgtagtctc gaagatccac
    36901 gccgccagta tgaatgagaa gatgtacgac gatactctca tctctctggt gtggcagtcc
    36961 aagctcagtc gccataccct gttcaagcag tgcgtgaagc ccaacaacaa cacttcggcg
    37021 ttgagattga gccagctgca gggccaatat gtcatccgct gcaacgccat cgatccctgg
    37081 ggctacgagg acttctctct tgacatcaac gcgccccgtc gcaacgatcc cgccgcgcgc
    37141 gccaccttct ctctcggaaa actgcagggg gctatgatcc tcgctctaga ctgcgacaaa
    37201 gtagaccaga tgcgcaagat cctggaaaag aaaagcaccg ccactcaaca tagcaatccc
    37261 gagtccgatg atgataatga gatggacgaa cacttgaccg tccaccgatt cagagacgac
    37321 gacgctaagt ggcgagtcta cctccagtac gcaggtacct gcaacggtct taaccaggtc
    37381 gatgagcaca atgagcaggt cgggttcatt gatttcaacg ttgaccctga gcgaagtgac
    37441 gatgatgaga aagctctggg ctatggtctt gcgtacggac gcggtcttat cgtcggtcct
    37501 aagtatatga cttcgcgcaa gagcgacaag ggcgagattc tggagattga ggtcttcaag
    37561 tggactagtg ataccgtccg agtcgcggct gagtggaatg cgtttaactt ctggggtgga
    37621 tttgaagccc gattcagagt tggtgagaga gctatgacta tgaccaaggg gtatgagctt
    37681 tagctctctc tctttctctc tctcactgtg atgctctggt ttgaagtgat tgttgcttac
    37741 ctctttcttg tttctttttt atttcctttt cttcttgttg tcttctgaaa agagaaaaga
    37801 ggaaagaggg aaaaaaagga agaaaatatg tttttgtcct cttgtttgtt attcgattgt
    37861 ttttccaatt ctgttgtttg tgttctgttc ttgtttctta ttctgaaaag ttgtggtatg
    37921 attctgattc tcatgtacga tggatgggga aaaaagtgag ctgatggcgt cgatggtgtt
    37981 cggttcttat ttctttcttt ttcttcgctt cattttgcgt gtttgaatat acccaaggga
    38041 tgtagggcgg gcgtcttctt cttctttttt tttttttttt ttttcctctt ttttcttttt
    38101 tcttttcttt ctcttaatga atggacgagc catgatgacg atggtcggga gatggacgat
    38161 gtggatgaga gatggctctt gtttcaactg atgataggat gatgggggaa gaaatatcga
    38221 gatgtaggta tgtatttcag ataatggtca tcaaccttag tgacagttaa tgcaattcat
    38281 tgaattggga cttgtgcgtt tgcattacca gtccggatgt aagcgtttcc ggcattccgt
    38341 cttcatcttc gttttcatat gggaactact agctagtatt tctcaattca atatgaaggc
    38401 agcaaacgcg cagagagcaa ttacgctaag tacaccgtac cctgtgacct acaaacctaa
    38461 tccccaaggc cagggtgaaa gaataaatga gagaaacatt catcagctgc acaccaaacc
    38521 aatggaaatg ggtaaggata tcaattcaaa catctgccta agaccactac tacatctgcc
    38581 taaagatggt acaaatcacc ggtagaacga cgctgggtta gatacatccg tttgagacgg
    38641 gttatatgcc tggtatcctc cgcccgcgtt cagagcagga taaggtgtcg gcgttgtgga
    38701 tgtacctggg acaggcgggg gctggtgcat aggcggcggc tggtgtgaag ggtaaggggg
    38761 ctgtgcttgg tgggcagggg gtctggaggc gtcttcagga gtgtagcctg aggccgggta
    38821 ttccgggtgt ggttgttgcg actgctgttg cggctgctgc tgttgctgtt ggaaatgctg
    38881 ctgcacggcg gccgggacct gcacggcgcc gggatatggt ggtcgctggc tggcaggatg
    38941 ctcaaccggg gaatcgtaga ccgatgtgcc gagttcttgc ggattctcgt atgtggactc
    39001 cggacggtgg tacacgggct ggtaggactc cgaggagggt tgacgttgct gctgtggttg
    39061 ctgctgctga tacggagcgc cagcaggtgg tgtctgacgg ggatcgggcg attgtgaagt
    39121 gggaggatat gcgtgtgctt gttctgtgcc gtagaatgcg ggcgcgttgg ccggaggggc
    39181 ttgtgtttct gctatgtgtt tgttagacat gagctgagaa tgtatccatg cagcacccac
    39241 cttgaggacg gggactgaag tagcgttgag gatcagcctg tggcggccct tgaggatatc
    39301 ccacaggagc agcaccagga tagccgtaag gaggttgagc cggccggcca tactgggatt
    39361 gtgctgggtg cgccatggac gcctccagca gagactcgta atctctccgc gccttgatga
    39421 acttctcgtt gagctgcgtg aactcgtctg caaagcatta gcggagaata gcgacatgcc
    39481 gaaatcatct tacccttttt ctgcgagtat tttccaatga gctcaatcag cttggggcga
    39541 atggccaatg tagagtgata cagggccgtg atttcttcat tgtcctgcac attcagctcg
    39601 gagctccgag tgctcagaag agtcaacagc ttttccacat ttttaatctg accgaaaaca
    39661 tcggcttcca tctgggcttc ccgctgcaac tcctccaccg tcgggtcagg aagtttctcg
    39721 acgtagttaa gggggaagat gccggtctgg cctctcaagg aacccttcca ccaatccttg
    39781 tagacggact cgaggacagc gatgacatct cccttgcgga actgcaattc accgggttct
    39841 gaaggctgaa agtcgaacag ggctctcacg cgcgacactg tggcggccga agtacccgac
    39901 gggactgctt gggaggtggc agcaggtgcc tgagtttggt tgactggagc agcgctggag
    39961 ctggcttcag gctgcggcgc aggggcgatc gtggcctttt ctcttatcga aagtgcgagg
    40021 gccatttgca gctcctcctc ttccttttgg cgatctgcat cggtaatttc ccgcttcccg
    40081 ggcttggacg gtggctgcag gttcgggtct aagatagtga gcttctctcc aacattcata
    40141 actgctaacg atcttactct gagtcttcag tttcatgtat gcttgttcca tgattccgaa
    40201 atctgggtta ctggcgaaca tctccgtcca ttcttgcatg cgttctagga tcttcgactt
    40261 gacctgctga tgggtgttct gctcggtata agtgcgatgc tcttcatccg tgaaagtcca
    40321 acttactctg tcattcgcta gacgtagcag agcatcggtg aagctcctag aagccaactc
    40381 gcgatgaatc ttgggaccgc agttctgagc gagggcgttc gccaactata gccgtatcag
    40441 tacacgtaag ccctcaaaac tcgggcatgc caccggatcc agcacgaacc tccaaagtat
    40501 aaagctgcac attggcgttt ctgtgcgcaa gtctcttgat catagcggcg acggcatctt
    40561 tcgctctaga aacaaatcca ctgtcagaat gacgtgcacc gaaaaggaca accgaacggc
    40621 gaagcatacc ctgactcctc ggcaccaact ttatcgcaaa catcctaaac acaaccaata
    40681 gctccagtca gatatatatc cttcggccga tgcatggcag atttagcgat cgtggggttt
    40741 gcgtaccagg atgtattccc agttttcgga ggtcaggttc tcgtcggtcg ccttggctat
    40801 accacatcgc tcgggttagc aacaagtata agagagtaga gctgcacggc gtgcaacaga
    40861 ggatgtgtgt ttcataccga ctgcatcgtc aaaggcgttt tgctgtgcgc gaaacatcac
    40921 gggggttgtc tgcgagcgcc cggggcaatc tcactgcgtt gcaactcgga ctaatattcc
    40981 acacgaacgc gtggggtttg attccgcggt atgaaaaaaa tgttacagaa gctgttgtgc
    41041 tcaaggaatg tattccagta atgcaggtcc ggttctctct ccttgttgta ggttcgatgg
    41101 ttcacggtat ccaggccgcg agatgacacc cgatgcgggg gacactgcgg tcagcgggag
    41161 ccggagtaaa cgaggtcggg atcaattgag gcgctcgtgg atcaagatcc cttaacagac
    41221 gggggaatcc accaagacag attatcggac cacaacgaag gacggggagg agaagatagc
    41281 agctggaaag ccaaggggaa agggaaagac aggctgccac ctgatgttta gcaggtgatc
    41341 gcgccgacgg agagcagcgc ctctgacgct gactggccgc gctacgcccg attaagcgag
    41401 acccgcccct ttatggtcta gtggggcacc gccttccatt gacgttggca aacaatgacg
    41461 atatcctact agtacttaaa acacaactac tgcgagaggt ctcaagggac tgttatgaaa
    41521 atataccccg ggtgattcct gatgattgat cgaaaggtaa ataaaagtga catcgtggtc
    41581 ttcacgataa ataacaaaga ataataatca tgaccatccc tcacacataa gcaatagccc
    41641 atggcactaa agatccctct atatcaatgt aaccgctcaa ataataatcg tcaactcaga
    41701 acaagacaga caaaagctcc acacttttgt tcttttttgt cgtcaaaaca gtcgggaaaa
    41761 tgcctcataa atcatcaaga atatcggtcg ctggaagata tggagatggg aacaacccaa
    41821 cagctgcacg acaagtaaca ataagatggg ggccggagac cacgccgacc accggcgccc
    41881 gttcattata tgaagcttca agcctcctct tgagcttcgg ctccgtgaca atagtaagca
    41941 ctcacaaacg acaatattga caatagctgg acggatgtcc ccaggagatt gtacaggctt
    42001 tttcactcgc tcaaaagcca acgtcgaaag aaagaatctt gcagagaaaa ctcgtcaaga
    42061 aggaaggata tctccgcagg tgtttagtgg ccagcgacgg aaatcaagcc aagcaaaaaa
    42121 aaaaaaaaag taaaccggat agacaagtca ttatccgatg aggtcatcgc cttctagaca
    42181 ttcacaggag atgcgaaact gccaacatga gtagctgcga aaaagggtcg gccataatgc
    42241 aatgccagcg tcattgtcca gcaaatatga aatatcaggg gggtaatggg tatctgagag
    42301 agagaggaca gaagacatcg acgtatatag taacagttga aagtgacggc acctaggcgc
    42361 ctcccttttg agctttttcc tgggctctgc tagcccgcgc agccttgaca aggggcgaga
    42421 gatgattcag gggcgcgcaa agcgacataa acggatgcta atcgagcagt tagttattat
    42481 ttcacaatga gcttgattga cgtgaacata ccttgagcaa gtcatgtgcc gaggctcgct
    42541 tctcaggatc caccttgaga gcaaggtgca ggaaatcacg gaagacgggc gacaagttgt
    42601 gctcatcctt gattgtaggc gtgccgttgg tggcaatcaa gtacagagcc ctcaggggcg
    42661 attccgtaag ataaggaggc tcaccctcga tcatctcgat ggccatgata cccaaactcc
    42721 agatatcaac cttgcggcca tactcctttc gagtaacgac ttcgggggcc atccaatacg
    42781 gtgtaccgac catggtgttt cgcttgttat gcgagtcgtt gatttgggca cagaaaccaa
    42841 agtcggctac aggatgtcag aaaatgaaca ttgggggcca tcgcgaaagg tagcttactg
    42901 agtttgatgt tgccctccat tgagagaaga atgttgtccg acttgatgtc acggtgaatg
    42961 acacctttcg agtgaagatg ctgtaaacca ctcaaagtct agtaaaggtt aggagatgcg
    43021 agatacatta aggagaaaga tgcagtaagc ttacctctct gcagacagca gcaatttgcc
    43081 cttcactcat aatgttgaaa gtaaccacat cagtcaaact gccaccctcc atgtactcca
    43141 tcactaccca gaggtccaga ccatggaggt agctgtctaa gaagttgaca atgttcttgt
    43201 gcttgctgtc cttcatgacc aaaatctcat tgatgatcag atccttcttg ggttgcaagt
    43261 ccaggttcat ttgcttgata gcaacacact tgttggtgtt gttctcgtag gcagtgaaga
    43321 caccaccaga cgcaccctgg ccgatcttgt tgagatgatg gtatagccta gtagggtccc
    43381 cgggcgtaca gatggcaagt agtcgcgacc ttatatccat cgcattactc tgacgaggtc
    43441 gctgccgggg cgagcggcag gagcggcgcg tgcagcctca tccaccgggg agacatggtg
    43501 gggtgggctc tgcaccgaag gttgcttctg ttcctggcga gtaggctgct gttgacgctg
    43561 actgcggcta cggtcgagtt ggatggtcgc aattgcctgc tgggcggcgg ccattgcttg
    43621 ctcttgcttt tgttggtact gagccggcgt aggaacattg tgtgactgcc atggtacggg
    43681 ggtaccattg gctctggagt ttgatctgct caactgaggc ttaggttcag actgcagggg
    43741 ctccgtttcc ggaatgggag gcgtgtcgaa ctgcggagga gaataggcct cttggggtgg
    43801 acgtgcgggc gcggcactgt atgatcccgc ggttggtggc tgtggtgcag gccgagacgg
    43861 ggtgatattg gcaggggtcg gaggttttgg tggtgctcga ttggggacaa agccacctac
    43921 gctggggtgg ccgcagaagg cccacgagga ataggaggcg gcgcacgtgg gttttcgaag
    43981 ctaccctcat gattctgtgg aaagcgagga ctcgtcgggg gagaagtccg agctgaggta
    44041 gggccgtaag acccggcgcc gacagcatta gtctgtcctc cggaaatcgg gctggaaacc
    44101 gactgcggct gaggataagc gtggtcaaat ttgtgccaca cttcgtcatc gccttgagca
    44161 ttcttctcgt agaacctcat aatatcaacc atcgtctgcg ggtgttcctc ctgctccttt
    44221 ttcgagatac cgttttcttg cagcagccgc tgccattcct tcgggaggcc agtgaactga
    44281 ccggtctgat tgtcatagcc aacgtgcgta acgtgcacgg ggttctccgg ggcggagatc
    44341 ttgatgcctc gggggagcct aacatgctat tgacgaagct ggagaaactg ctctttttgc
    44401 tcctgcccgt gccaaatggc cgcgagccaa caccaccacc accctcatcg gataaacgtt
    44461 ttggattcgc cgggcgatca ttgtcagtcg tcctgtgcac gaatgtctcc atccggttct
    44521 gtagagccgt gaagctagca gactgtctca atcctcggga gtccgggctg gtggccgatc
    44581 ggaggttggg ggtttttggg gaacggtctc ggtggtattt tcctgcaatg aactgagcat
    44641 gccccggctg tcaaacgggg gtccgatcaa ttcatctgaa ctttgctcgg tgagagagaa
    44701 tcgacccgag tggggagggc gggatttgga ggggttggag gtgttcgaga agtatccagg
    44761 ttggttgcca gcgagcaccg gagacgggcc gccactattc tgctcgaggg aggatgaaga
    44821 agatccgtag gcgttggacc ttgtccgcga gtgctcacga ctcccaccgg tggaggaacg
    44881 ggggtagacg ggcgctgaag ggtgccgctt tagtgacgtg ttgctctgct ggctcttgag
    44941 gatgcgggag ctgaaactcg gaggatcctt gtgaagcttg ctagacgacc gtcgaaattt
    45001 tagggaggag aaactatcgt gattcatgac gtgcaagttt tagggggaga gtgggttttg
    45061 ggggggtgcg tggagggaca ggtcggccga ctggcagcag cagcaccagc agcagtgcag
    45121 cagcaccagc agggttgagc gactggggat gggtggtttg attggaggga ggggggtggg
    45181 aagaaagcca ccgggtgagg cggtgcgcag tgcggtaggt aagagtccct accgtccgtt
    45241 tcgacgatag ggtggacgaa caaggccgct aggcggggat tggggggggg ggttgatggt
    45301 gtggtgatac tgcacggtca gatcgatagc cccaaccgga tgagtattgt tggatgaacg
    45361 gaggaatcgg agatgtgaga aggacccaga atgtctgagc gacgcaaggg agggcgcgaa
    45421 agtagcagcc gcggactacc gtcaaccagt ggttagcacg tggagagccg ctggatggat
    45481 cagagcagag aaagacggag tcgaccaaca gaggcggtga ctggctctga gggataattt
    45541 ggggaggata aaaaaaaaga ggggaagggg aggggaataa tactggtagg gaaaaataat
    45601 agggaaaaag caagaccagg tgagagggtg attcactgag atgcaggaaa agctgcagat
    45661 aaccgacagc tcagcacaca gatctgcagc gccaaaaaag caataatgca acagtcactg
    45721 ggaaaccaac gatgacggag aaagaagtgg gaaaagcacg gagaattgcc atggggggga
    45781 aagagtgaaa gagggtaact agttaagagg aggatggagg gaggaggagg gaaggaccca
    45841 gcaaggtgct ttttagtttt ggagacttgg gattgggagg tcgaaccagt ggcagcagtt
    45901 caacaacggc ccgtcttgag agtcagtccg acgattatta cactgggtac tcccgtacta
    45961 ccatcagaat aacggggccc agccactgaa actgacttac ttggcctcag gtgtgatggg
    46021 gaccatttaa tatcgtttgg gcttagcaga gagtagtaat ttactgtgat ttggtttggg
    46081 tacggtaaag tcagaactta agctgcagtt atttaacttc ctactttctt cttacaaagt
    46141 attaacttac agtgagatag agggtagata caaatagtta ccctcgaaag gacaagagaa
    46201 agagacaacg acgtagagaa gttgtcaatc gggcggtcaa caccattcca gtcaattacc
    46261 aaagcaagcc aacaaaaata aaggaaagcg agaaatgttt cgggtgccta ttttctgcct
    46321 ttccgttttc ccctaaattg tccaacaata aataaaaccc agttgaactg ctgtgtacag
    46381 ataatgaata ttcattctca atcccagaat attccaaaca ttccctgatg gatgagtttg
    46441 gatattattt ttccggggat ggggctcatt ggagagattg ttcccgtact ttttttttgt
    46501 ttctgtttcc cccccccccc cccccccccc ctccttcaaa tccgaagatg gaaatattct
    46561 tctggcagct taagtgtctc agataccgta ggtccgatta ggcaaagaga aaaattctag
    46621 acacgtcttt gaccccagtt tgcgtcccgt tggcgggtgg atcgcgaaca gatgcctttc
    46681 ctttctcgga acgatgggtt ccaccggttt tccgctttcc ttctgcttct ctttcgacac
    46741 ctcggatatg agacagattc caaagagttg accgatttca gagatatgaa aaggagggtg
    46801 tacaggaagc aggaagcaga agaaaaaaaa atatttgggg aatttcacat tccccagtct
    46861 gtgaaggaag cgacaaaaat aggaaagatc ctaatactag gggctgacgt ggtcaattag
    46921 cacaagaact gctgtacaca gtagtctact tacttcattc actcaatcaa caatttctta
    46981 ctgatggaga cagctgggtc tctctctctc tgcctctgtc taagcagcca aaaagcagca
    47041 ccagcagcac agcaactttg gttagacacc tgggaggagc ggccttagtg ccacgctagg
    47101 ccgagcgggg cgggcgaaga aagactaggt tccaaccgac ttgtgccgca cccaaccctc
    47161 ttcttttctt tcttttcctt ccataatgga attaaggaat ttctcccctc cctcatttaa
    47221 ttattccata acacggtgga tacgttccca tggtccaggg caagccacca atatttagct
    47281 tcattattga tctggagtcc gtgtagcgtc atcgcttgct ttctctctac gaattccaat
    47341 ccgctacagt tgcctcctac gtcctcgtat cttcctgctt tctcttcccg gagctagtct
    47401 atctatctat ctatctactt atctcgccat ctggatcgga tttagtacgc agtcgtaatc
    47461 cagctgcgct tgttaatgaa ttccacgagt gaaataaaaa aaacaataac agaatataag
    47521 gtctgaaaaa aaaaaaaaaa aacaaaacaa aacaaaacaa aacaaaagct aaatctacac
    47581 tcggacctac agagtagtag tatctactca gacctcggaa tatgaatatg gagtaacttt
    47641 cgagctgatc acgggtcaag ttgcttccct ttcaatttta gcctctgatg atcccgttga
    47701 aatctctgca ggtacggtgt agtttagttc gttctataca tcagctccct cttaccgcgg
    47761 aaggcttatt gtgtcttccc tcctcaaccc cgaaccgggt acggagaagt acggagggat
    47821 taggtactga caggcatcgt ctctcaatca tgacatgaca ctcgcgcaaa cacccctgca
    47881 cctgcacctg cagatgattt gagagaaata atagctacta ccccggccga gtcacacagg
    47941 tgtttttgtg actttcaccc ctgaaataaa ggagcagagt aaaaattaca atttacacag
    48001 atagactctt gctcggatgg tgggttctga tctgatctca taccatcaca caaggtagtc
    48061 tatgtgactg gtaatgataa ccacgagcag agaatcttga tgtatttggt tctagaaaag
    48121 ctttcaccga ctagaaattc ttgctgagta ctccataagc atgcaataac taatcaccca
    48181 caggacgaaa gctgacttaa ttaactgacg gaacggattc cattccttcc atccattgca
    48241 gcggggatga agtcagagtc cccgagacgg agtgactccg cactctaact aacttactgt
    48301 atgaagacgg acaagaaaga tgtatccgct caacaactct agatatcact tcgacatatc
    48361 acttatttat atatgaaact tggcttttga atcgattata caatactctg cacatcccaa
    48421 ttgaataaac aattacataa acaattaaat agtattgatt gagtgggatt gaccagtcta
    48481 ctcaaaactg ccatggcgcg ggatcggcaa agcccgtcat tttccgtctc ggcacaaaca
    48541 aaatgggatg gatggtcgag gcctagaact ttgggttttt ttttttttca tcttgggtca
    48601 tttttcgtta tttttgaacg ggcgtttcgt tccaaggacg gaataacatc atctacttac
    48661 ttactcgagg ttgcagattt aggatgagtg gtctgatgtc atggcggccc tgtgtgtgcg
    48721 aaatcgatcg aatcagatga tagtgatttt tcttctagaa aaagttggat ggtattcatc
    48781 acatcccatt tactgcgcca cgattgattg atgcagtatc ctggccatac tcggtcatcg
    48841 tgtacggagt agatagtgga tggcatgact gataattagt atgactgctc tcaatgttca
    48901 cttaaatcag tggcatagcc ccctccccga agccagattc tcctacagtg tcagtctagg
    48961 cagacattca ttttctcttt cttgttcaag gccctcatgc tcggtcattt gcgcccatca
    49021 gtccccatcc aatgactcgt aggaactttg ttagcgtgga gactctcgaa catgattcaa
    49081 gcaagctaga agccaaactt cgttcactct tgcgatcgct gacgtcacag gacccaactt
    49141 agcctgcgat ggaaacctga agccattact gtactgcttc tggtatagcg acaaagtaaa
    49201 aaaaaaaata ttatctacct catccattta tttccattac agagaggaat ttacataccc
    49261 ccgaaagaag aacaatatta tggaactcct tcccccaaga cctataggaa tcttaatttg
    49321 gaccctaaaa atcaactttc caactatcta accaacatcc attccccatc ttaatcccaa
    49381 taataaaatg acgagtaact gcagccttga accgaggtaa gctagatggt ttgttctgtt
    49441 gtcgttgttt catcatcagt cccaaaaacc agaacttcga cgatcaaact taccctaccc
    49501 tactgtatcc ccccacccac caccacccac tcccactaac cggaccaaag ttactactga
    49561 ccaattttag tacaagatta gtctggtagt taagttaagc tctgaaactt gccagcgatg
    49621 agaggggggc gaaagtatat aggcaaacac gtgggggggt gaagttctac ccaatccatg
    49681 ccgaatattg attctatcaa tactgccagg agttggaagt aactcttggt acttgacagg
    49741 tattgtttca tgcttgaact tagataatgt gttgtgttag cttatatggg ggaagagagg
    49801 agttgtgtat taggtgatga cagtcggctg ctagtcgctt attgggtagg gtgtatgagc
    49861 tggtgagaga gggaggacta ctactactac tactagagtt ggattgagaa ggaggtcttt
    49921 agtattgaac gtatcaatat actgcttctt ggtaagtcta aattgaattc atattgcagt
    49981 tacggggtgg aattgacttt tgttgcaatt gttgttgttt gtattgcacc atatctttat
    50041 acactatata taagaaatga ggaggtgata ttgggggata gatgtttcat ggatgtgtat
    50101 gcgtgctggc aggtacttag atacatacta atctactttg gctgatgtgg tttcgtttat
    50161 gtacttcaga gacaaggtgc atgtagtagc tatccaatta tctacttgaa aatcaagtgc
    50221 tattgttctg gtggtatgat tatagcagag atcataggag ttgcattatc attaaccatc
    50281 aatatatata tcgtggcctg ccgttcatcg tcatgataat atgatcatag tgtacatgtg
    50341 ttgctcatct accgtccaac gtacttcaac tccagcttcc gcaagggaat atacgataag
    50401 ctagtaaaaa caaacgccag ctcattggca atgtctcctc catcggtgcc aatcttgcgc
    50461 gccagcgctc caacataata cgtttcgtcc atgccgacaa tccagccggc cgcaccgcat
    50521 aggaacgccg tgagaccggc gtagccgacg ggcagtttcg acggcgtgtt ccaggcgtcg
    50581 aggtcgtagt tggccaggtt gccgttgcgg aagaagtagt gttcgcagaa caaaatgacg
    50641 aaaaaggagg tgttccagta acccaagagg gagaggaaat tatccaggac agtcagcagg
    50701 tggtcccggc ctgcgatacc aatgacaaga atgcaggcga acacgagtag tgtccaaata
    50761 attcggggga tcttctggaa gggtttggcg aataattgtg ccgaaaggga tccagcataa
    50821 atggcaatgc agttcatacc gactatattg tagtgttagt agcggttatg acgtgaggta
    50881 agtgggtata cttactgcca cacagcacca gcaagaccaa gaggaactta gcaaatttgc
    50941 ggggatagat gatggtctgc aagatctctc cagttccttg gtcataggca gcagcccatt
    51001 ctgggtttcc gtccagggca gatgcgatac acgcaccgag caacattccg atacaagtcg
    51061 ggagtgaaat acccagggtg gtgtagatga agaccttgac cttcgaggtg ttgaccgggt
    51121 agtgtacata aaagtcagac acgatcgagc accacgatgc actcgagcca tagataacgc
    51181 tgatcaggct cagaacattt ccggacttgg tcagcccgga cacggtaccg ggatctgaca
    51241 ggctggcgtg gtgggccgat tcaccgtaga cgatgatgaa gacgacaaag gaaaccatcc
    51301 aaatgtattg ctcaatggtc ataacagccc taagaccgaa gaagctgaaa cacagactaa
    51361 cgcatgcaac aatgacgact cccacgacca tggaaatgtg attgtccgaa acggcacgaa
    51421 gagcttgacc accagtaata cagctgacag aggcccagcc cagctgttcg acgacattca
    51481 gcgccgcgat gatggaggag gggtagaagc caaaggagta tctagagatg gcgacttgac
    51541 gaaggccagt gccagggccc atcgtggcac accaacccta gtgaaccgac atgtaagcct
    51601 ttagacagac cataagatga gtgcgccgca ttgcgtcgca gcgaaagata ggtagagaaa
    51661 gtggtatgcg aaccgtgaga gcagcgccca gaaacgtcgc gcaaatcata atggcgatcg
    51721 tctgccctag ggtcaagcca aactccttcc ccataaagcc cgtactgaaa caactgaggt
    51781 tcatggtggc cgatgcccag atgaaggcca tggccaaggt gttaggcggt ttgcgctctt
    51841 cgggcaggac tcgatcgaga ctgtgggact caacgcccat tttccgatcc aacagctctt
    51901 catagtagcg gatgcgggcg aagaaaccgc taggtttaac cagggcgtgt tcctccaccg
    51961 aagcggtggc ctgcttcggt tcgatggggt tgccatcctc aagggttttg aaatccat
//
