LOCUS       NKJJ01000003.1         46443 bp    DNA     linear   PLN 19-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   NKJJ01000003
VERSION     NKJJ01000003.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 06:54:43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1234362
            Orig. end    :: 1280805
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..46443
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[1254362:1254414](+),
                     [1254469:1255316](+), [1255381:1259989](+),
                     [1260069:1260805](+)}"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(20001..20052,20108..20954,21020..25627,25708..26443)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..46443
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..46443
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T1PKS"
                     /region_number="3"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     mRNA            join(3493..3716,3776..4514)
                     /locus_tag="CAN33_31710"
                     /product="hypothetical protein"
     gene            3493..4514
                     /locus_tag="CAN33_31710"
     CDS             join(3493..3716,3776..4514)
                     /codon_start=1
                     /locus_tag="CAN33_31710"
                     /note="SECRETED:SignalP(1-19); EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CAN33_31710-T1"
                     /transl_table=1
                     /translation="MKLSTFLFSLLATSQVTLATPIPIVDVAELPSDTGLEIRSPNPAD
                     ELLAILEQRNTRVCEILNRTIRSIGTSKFTVVYIVMGSRLARQVCEYAGGSRCEEISYI
                     ISDGLLLAYVAAAHYSGAIPEGLPGKRDVDVSQDYFQLWETMLSSNGDISYDYLTPLSN
                     TSNTLPLVRRQDQPLPIHRIQITGFAHNNSPKHDIIANHYENGDTVLQLPLAGGVPGAN
                     DTEGLDLRKRFDNPGFKIAFTTRGRSQLTQAHQKSMALAGAATWAVYADNANHKMDDFI
                     GFAETDHAANFYYRIIPELRGFGTNYETVDICGGMASYL"
     mRNA            5596..6729
                     /locus_tag="CAN33_31715"
                     /product="Beta-lactamase family protein"
     gene            5596..6729
                     /locus_tag="CAN33_31715"
     CDS             5596..6729
                     /codon_start=1
                     /db_xref="InterPro:IPR001466"
                     /db_xref="InterPro:IPR012338"
                     /db_xref="PFAM:PF00144"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 114.2; E-value: 1.2e-34)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_31715"
                     /note="MEROPS:MER0011726; EggNog:ENOG41"
                     /product="Beta-lactamase family protein"
                     /protein_id="ncbi_CAN33_31715-T1"
                     /transl_table=1
                     /translation="MTTINGHCDPAFTGVRDLLQQLINNEEELGASICVNIDGQNVVDL
                     WGGHADPARTKPWEKDTLTVVWSVSKVITAIATNILIDRGLLDPNEKVSKYWPEFAANG
                     KENILVSQILSHTSGVSSWELPNTLDDIYDAKRGADKLARQAPWWTPGEHSGYHVTNQG
                     HLLGELVHRVTGKPLDEFIRDELASPLAADFQLGVPEKDWPRTADVSPPPPLSLDGVDP
                     QSVMFKSFASLPIPAEESMSPGFRKALIGATNGFSNARGIARIASVISLGGTVDGKQYL
                     SPETIDRMLEEQISGPDLVLMYHLRWGLGVGLPVPETFPWLPDGRIAFWTGWGGSVVVM
                     DLEKRMTIAYVMNKMGQGTLGSDRTAAYVRAVYDCLA"
     tRNA            complement(6992..7065)
                     /locus_tag="CAN33_57620"
                     /product="tRNA-Val"
     gene            complement(6992..7065)
                     /locus_tag="CAN33_57620"
     mRNA            join(7924..8920,8983..9602)
                     /locus_tag="CAN33_31720"
                     /product="Phosphorylase superfamily protein"
     gene            7924..9602
                     /locus_tag="CAN33_31720"
     CDS             join(7924..8920,8983..9602)
                     /codon_start=1
                     /db_xref="InterPro:IPR000845"
                     /db_xref="InterPro:IPR002182"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="InterPro:IPR035994"
                     /db_xref="PFAM:PF00931"
                     /db_xref="PFAM:PF01048"
                     /locus_tag="CAN33_31720"
                     /note="EggNog:ENOG41; GO_function: GO:0003824 - catalytic
                     activity [Evidence IEA]; GO_function: GO:0043531 - ADP
                     binding [Evidence IEA]; GO_process: GO:0009116 - nucleoside
                     metabolic process [Evidence IEA]"
                     /product="Phosphorylase superfamily protein"
                     /protein_id="ncbi_CAN33_31720-T1"
                     /transl_table=1
                     /translation="MSGNDVPSYDEFAVGWICALPLEMTAAKAVLDEEYPSLHLPKQHH
                     NTYVLGRISGHKVVITCLPFGIYGTTSATAVVEQMLFTFRSIRFGLMVGIGGGVPSAVD
                     VRLGDVVVSKPTAGLPGVIQYDYGKTVASGRFEQTGTLNKPPIVLLSALSSLEADRLAG
                     GSDIGTYEKIIADSLRAAKDPSVFRYPGAEHDWLFDASYDHDPRFASCAECDPERRVRR
                     KPRRSCTPVVHYGNIASGNQVMKHGLTRDRIAQTTQGILCFEMEAAGIMDYLPCLVIRG
                     ICDYSDSHKKKEWQGFAALTAAAYAKLLLSKIPVHRSEASTLIQAPGSKNSSDSFDVRF
                     DTIEMPQAAISVGREAELAMITKSLLSDKFRGIVTLYGMGGIGKTELSIMYIMRHRQKY
                     SSVFWIDGSSLDKLYSSYTQAAMRIIHDHPGDQSLRKALKEGDQIQLVGSVNEWLSRPS
                     NNRWLLIYDGFDLPMVEGFDKAEIMKMRLPPSKQGHIIITMRSYDIGIGDQIQVRKLAA
                     IDDGLDLLTHVCGRPNLRDGK"
     mRNA            complement(join(11181..12614,12717..12845))
                     /locus_tag="CAN33_31725"
                     /product="major facilitator superfamily protein"
     gene            complement(11181..12845)
                     /locus_tag="CAN33_31725"
     CDS             complement(join(11181..12614,12717..12845))
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 261; E-value:
                     2.6e-79)"
                     /gene_kind="transport"
                     /locus_tag="CAN33_31725"
                     /note="EggNog:ENOG41; GO_component: GO:0005887 - integral
                     component of plasma membrane [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="major facilitator superfamily protein"
                     /protein_id="ncbi_CAN33_31725-T1"
                     /transl_table=1
                     /translation="MEAAAHSLPSSQESDFAVNNHLPHREESDEKGHDADASATDDDGA
                     VIERFGDVSQLAWIGAGFPLGSVAVILPYGFLYTVMNMKWLYIAGIVLFQGGSALCGGA
                     PNMNALIVGRVIAGAGGTGIYLGGLNHFSAMTTRNERGTYLTGTGFVWGVGAILGPVVG
                     GGFSDSSATWRWGFYLNLVIGAITAPVYLFYLPAIHPGAGQSLRKRLTRLDYLGFVLSA
                     AMWVTFALGFISAGGIWAWDSGATIALIVLFGVLFILYALQQYLCIFTTPQTRSFPGHL
                     LRSRTQILLYITTTCANTAMFFTTFYIPIYFQFTRNDSSLMAAVRLLPYLLVTITINLA
                     IGWLLPKAKYYMPLCLISGILLTLASALFVGYLSPSTPAGQIYGFTILMAVGTGMTMQL
                     GYAVASLKVPPEDIFSAINLQNVAQIGATVICLVVASQVFQSTAVKNLKGVLDGRGYSE
                     AEIRNAVAGVQSTLLKSLSGELRDRAIKAITDAMARAFIIPLVAGAVGVVSSLGMRRER
                     LFG"
     mRNA            complement(join(13675..14352,14416..15444))
                     /locus_tag="CAN33_31730"
                     /product="Cytochrome P450 family protein"
     gene            complement(13675..15444)
                     /locus_tag="CAN33_31730"
     CDS             complement(join(13675..14352,14416..15444))
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002403"
                     /db_xref="InterPro:IPR036396"
                     /db_xref="PFAM:PF00067"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 125.2; E-value: 5.5e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_31730"
                     /note="EggNog:ENOG41; GO_function: GO:0016705 -
                     oxidoreductase activity, acting on paired donors, with
                     incorporation or reduction of molecular oxygen [Evidence
                     IEA]; GO_function: GO:0020037 - heme binding [Evidence
                     IEA]; GO_function: GO:0005506 - iron ion binding [Evidence
                     IEA]; GO_function: GO:0004497 - monooxygenase activity
                     [Evidence IEA]; GO_process: GO:0055114 -
                     oxidation-reduction process [Evidence IEA]"
                     /product="Cytochrome P450 family protein"
                     /protein_id="ncbi_CAN33_31730-T1"
                     /sec_met_domain="p450 (E-value: 4e-32, bitscore: 106.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MAPSYIASFVELFHGYPAVFSITICLVGLYVLYRWLLPSPLPGIP
                     YNKQAATSILGDVPALRGDPAGLAKWCSKQLEEHGSPICQALMGPLSKPVVLVADVGQT
                     RELLMGRSDFDRSSYIIDRFPLFGEFHLNMKTGDSWRTSRSWLKDLLAPHYLHQTVGPI
                     IHSSVLNLIHLWESKARVANGRPFSMLADLKTLALDVIVRFHFGQDFQDSALRRQIEFV
                     EQLDNSQLGVGKHTDVIFPQASLHPFQQGLTDVGDRMAAIYTTKWPPSIVSWWARYMSP
                     YYRKFFVGKDRFIRKHINLALQRFGNDEEAKTGIDYMVYREQKASRKADRQPMYGKQIM
                     IDEAYGNLIAGQHTTSAALVWILKLLAEHPAVQTRLRDELQTVCAAAVQEGRLPTAAEI
                     IQFRLPYLDAVLEETLRLRAAMLVPRDATRDTELLGRRIPKGTVVLLVCQGPDYSSSPS
                     SLYWSDVKTTRKYPGGGNPDLEAFDPERWLVQNERGELEFDGSSYPQLAFGLGIRACWG
                     RRLAQLEMRIMTVMMTWKFDFLDVPEALAGHEATYDISYRAKKGYLRLRSR"
     mRNA            complement(join(16151..17174,17233..17706,17766..17914,
                     17980..18261,18336..18401))
                     /locus_tag="CAN33_31735"
                     /product="Fungal specific transcription factor domain
                     family protein"
     gene            complement(16151..18401)
                     /locus_tag="CAN33_31735"
     CDS             complement(join(16151..17174,17233..17706,17766..17914,
                     17980..18261,18336..18401))
                     /codon_start=1
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR007219"
                     /db_xref="InterPro:IPR036864"
                     /db_xref="PFAM:PF04082"
                     /locus_tag="CAN33_31735"
                     /note="EggNog:ENOG41; GO_component: GO:0005634 - nucleus
                     [Evidence IEA]; GO_function: GO:0008270 - zinc ion binding
                     [Evidence IEA]; GO_function: GO:0000981 - DNA-binding
                     transcription factor activity, RNA polymerase II-specific
                     [Evidence IEA]; GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     transcription, DNA-templated [Evidence IEA]; GO_process:
                     GO:0006351 - transcription, DNA-templated [Evidence IEA]"
                     /product="Fungal specific transcription factor domain
                     family protein"
                     /protein_id="ncbi_CAN33_31735-T1"
                     /transl_table=1
                     /translation="MHPTGRKRRVTTCVPCYTRKQRCNRQYPCNHCTRRRRPEECVYQS
                     IITGDPSNTFLLEPARDPEPQEPPNVQLPNGSSKASPAEAQNSASNSHSALAKSFGYFE
                     HSDSNTMALLKKWDLDSEGDTDQSTQGLSTAVLETVKQVLEKIPPRPILDFLMQYFVDE
                     LNWMKQIIHPPSFLTQYQHWWTKEWPLPVDDIEFAALVLRIGAYSAQFLPSPTHTLDRI
                     RGQSLSDIRDTCSHLGGELARACLSLNWKGSLVRVQHILFAAFRSSCEGRTDKFWEGIA
                     SACSAAQKAGIHTVAPVPGEDSSQVLEKEMRRRTLCGLYVLDSHLARQLDRVPFLPDNL
                     VLETLPRLRLAPFIGDLAASADAPEDFTERLMQVRLGRFWRSFGSRRNLPYDPTHGEQR
                     YERFCAEYIPTLPPAYALNPDRRWDGQLPKLPMQRQLLYIAIFDSVCWNFRPLLLLKPG
                     QVTSLPPYKQVLLQSQKQKLALAALEELDAVTALHIMFGGSHTRFSAIIFNTFEAAVVL
                     LILCTQKDFPFDQGEDHPDILGLRVATLTRPRAMRAVEKALGRLQMLAEVSEMAASGAQ
                     VVTQLFAKAARMEHSLEPYTPNESSRSSSSPAILSNFLNLEDGSGLWMSSEDPTLMPDM
                     LSTIAHGDSYSMLQFPSLDLTSWNGNFHS"
     mRNA            join(20001..20052,20108..20954,21020..25627,25708..26443)
                     /locus_tag="CAN33_31740"
                     /product="Beta-ketoacyl synthase N-terminal domain family
                     protein"
     gene            20001..26443
                     /locus_tag="CAN33_31740"
     CDS             join(20001..20052,20108..20954,21020..25627,25708..26443)
                     /NRPS_PKS="Domain: PKS_KS (11-437). E-value: 2e-148. Score:
                     486.5. Matches aSDomain:
                     nrpspksdomains_CAN33_31740_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (587-904). E-value: 6.8e-83.
                     Score: 270.1. Matches aSDomain:
                     nrpspksdomains_CAN33_31740_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (984-1161). E-value: 4.7e-33.
                     Score: 106.6. Matches aSDomain:
                     nrpspksdomains_CAN33_31740_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1728-2010). E-value: 2.3e-32.
                     Score: 104.0. Matches aSDomain:
                     nrpspksdomains_CAN33_31740_PKS_ER.1"
                     /NRPS_PKS="type: Type I Iterative PKS"
                     /codon_start=1
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR018201"
                     /db_xref="InterPro:IPR020801"
                     /db_xref="InterPro:IPR020807"
                     /db_xref="InterPro:IPR020841"
                     /db_xref="InterPro:IPR020843"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="InterPro:IPR032821"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="InterPro:IPR042104"
                     /db_xref="PFAM:PF00109"
                     /db_xref="PFAM:PF00698"
                     /db_xref="PFAM:PF02801"
                     /db_xref="PFAM:PF14765"
                     /db_xref="PFAM:PF16197"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 215.8; E-value:
                     1.8e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="CAN33_31740"
                     /note="EggNog:ENOG41; GO_function: GO:0016491 -
                     oxidoreductase activity [Evidence IEA]; GO_function:
                     GO:0003824 - catalytic activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /product="Beta-ketoacyl synthase N-terminal domain family
                     protein"
                     /protein_id="ncbi_CAN33_31740-T1"
                     /sec_met_domain="PKS_AT (E-value: 8.6e-82, bitscore: 270.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 2.7e-150, bitscore:
                     496.1, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTPPRSNECEPIAIVGMGCRLPGGVQDIPALWEFLRDQKDAHGEF
                     AAPRFSAEGFYHANSDRPGTAVASSGFLLKEDPRLFDPSFFGITDVEAETMDASQRKLL
                     EVTYEAFENAGETWDSVSGSRIGVFVGDISFDNYVSQTRDWDYSGKYSATGAFPNMLAN
                     RIHYVFNLKGPSLLINSACTSAMYALHLAITSMRNGDCDSAIVAGSNWVMDPNCHIAMG
                     KLGALSPSSRSHTFDASADGYARGEGFAALYLKTVSLATQDASPIRALIRGSAVNANGR
                     TSGITNPSGPAQETVIREAYKNAGDLDPSETTLLECHGTGTRVGDPIEVTAAGNVFGPS
                     RSTVHEDRLVVGSVKTNVGHLEGACALPGILKVVASLEAGEIPATLGFQTPNPRIDFDQ
                     AKARVVNKTEPWPKDRLKRASVTSAGFGGTNGHCIIDHVHNVIPEYVKPGVIYEQVEQS
                     NGTNGHAVNGTNGTNGTHGTKPEALSQLHRPILHSPTLVRRADATTRQMVVLPFSAHNQ
                     SSLIANMEALQRSIPHHSLADVAYTLAAKRSRFSQRAFSIVDKDQVTQVGSVTDNGPKV
                     FASPQRVNVGFVFTGQGAQWPAMGAELFEYAVFRDTIAYLDTVLAVLPQPAPWKLVDIL
                     CGNCDKDLIQKPAVSQTVCTALQMGLVDLLASWSVRPAGVVGHSSGEMAAAYAAGRITA
                     AEAITIAYYRGYMVSFNQKKGAMLAVGLGADQGAEYVRQAGMEGRVKVAAINSPASITM
                     SGDADAIEQLSVQLTQEAIFNRQLRTGGLAYHSHHMLSFGHDYAQAVDDGLQRLASLGI
                     NDTTSRYSNIPWASSVVPQKSSTMPREEVTASYWKANLESPVRFTDAVSKLLDMDDLRI
                     GATVEIGPHPALKGPLGQIVKGLGRTIPHVASVERGQDARRSLLGLAGTLFALNADVDL
                     VAVNAVDESHGAGKRTLIHGCMAIDLPPYRYTYGPIKYHESRLSKEYRLRRWPRHDLLG
                     ARVPGTTRLRPQWRNILRLKDLPWLNDHRVPPHVLHPGAAHIVMAMLAAEQAYAEFPDA
                     LPVAGLTLRNVSIKKTLVVPQDDKGIEIVLSMELEDGATAASPGWASFSIASVVNDSEQ
                     WTEHCSGLVKVDVVAFNAPAAIDTTTMDGRAVDAQAWYTRFADMGLQFGPSFQGYSDIW
                     ADPFSNVALAKLSLNTTAGLFPGGESRYPIHPASLDLVIRLGLMACNGGQAETASVQLP
                     IHFDQMRFKLGCLQGRDWITGVSRGELRGLRGAYAQLQLLDDSGEAILDVDNMRFTSLN
                     NEQQSSAQDFSGQAYSSPFARLVWRPDSRTLSRDQWNKLLASVDGTTTFSRLSYLFDLV
                     GHANPDLRILQLSAGSDDRNAGQAVLKSLVGHNGIKRYREYVATDTSAERLDSFRETVS
                     AFRDVRYSVLDISQDPSEQEFQIGTYDMILWSNVEHGPATEQALANAKKLLHPGGHLVL
                     VDRMNSSELAWDQCLRRVGFDSGYKLVCREADLHSTIILSTLPDPVPTTKSGNPVVHLL
                     HGSQGTSALLHHLARAMEQHGLSIRISPMDQAINVLAPNSRVVAFLDGENLLFAADQRR
                     LGLFQHLAANTASMVWVTSCGLVKGRNPDGAFVSGLLRTLGTENLAGQFLSVDVDAEDF
                     QVPGLEMDELVRCLVEQELLLQPTLDDKGPPEVNRDLVWQDGCMWTSRIVPDGQLQGYA
                     EVAPTRQEVDVSSRPLSSLGPVRAAFETPGILTSLYFRPYTELLQPLPRDYIDVKVDAV
                     GLNWKDLGLCSGRFDANNLSNEYCGVVTQVGADVTRLSIGDRVYGMGKGHFGTHTRVPA
                     GLAQKLAADVNAIEAATMPLVRPWSGSHPAGAVQGATIYATAGTADKVRFLTDHMGVPA
                     SQIFSSRDLASLNRATQQHGGFDVILSTAQGDMLYESVKALAPLGHLVDVGRLDVTSSQ
                     TMGLELFQKSAGFTSFDLGLVVERDSVLGAELMQSVDAHFRAGHIGPIKPYSVADIGHL
                     DQTLLQFSQGTHIGKRVITYQDPSTLLRTLPTSSATPARFDPAARYILVGGLTGLGRSI
                     VRWMSSRGARDMEVWSRRGQATLPPKHSV"
     aSDomain        join(20034..20052,20108..20954,21020..21431)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_31740_PKS_KS.1"
                     /evalue="2.00E-148"
                     /label="CAN33_31740_PKS_KS.1"
                     /locus_tag="CAN33_31740"
                     /score="486.5"
                     /tool="antismash"
                     /translation="IAIVGMGCRLPGGVQDIPALWEFLRDQKDAHGEFAAPRFSAEGFY
                     HANSDRPGTAVASSGFLLKEDPRLFDPSFFGITDVEAETMDASQRKLLEVTYEAFENAG
                     ETWDSVSGSRIGVFVGDISFDNYVSQTRDWDYSGKYSATGAFPNMLANRIHYVFNLKGP
                     SLLINSACTSAMYALHLAITSMRNGDCDSAIVAGSNWVMDPNCHIAMGKLGALSPSSRS
                     HTFDASADGYARGEGFAALYLKTVSLATQDASPIRALIRGSAVNANGRTSGITNPSGPA
                     QETVIREAYKNAGDLDPSETTLLECHGTGTRVGDPIEVTAAGNVFGPSRSTVHEDRLVV
                     GSVKTNVGHLEGACALPGILKVVASLEAGEIPATLGFQTPNPRIDFDQAKARVVNKTEP
                     WPKDRLKRASVTSAGFGGTNGHCIIDHV"
     CDS_motif       20761..20799
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_31740_0001"
                     /evalue="2.30E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="CAN33_31740"
                     /score="14.1"
                     /tool="antismash"
                     /translation="FDASADGYARGEGF"
     CDS_motif       21063..21107
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_31740_0002"
                     /evalue="5.20E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="CAN33_31740"
                     /score="12.3"
                     /tool="antismash"
                     /translation="LECHGTGTRVGDPIEV"
     CDS_motif       21174..21215
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_31740_0003"
                     /evalue="1.10E-02"
                     /label="PKSI-KS_m6"
                     /locus_tag="CAN33_31740"
                     /score="8.8"
                     /tool="antismash"
                     /translation="GSVKTNVGHLEGACA"
     CDS_motif       21879..21929
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_31740_0004"
                     /evalue="1.30E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="CAN33_31740"
                     /score="17.6"
                     /tool="antismash"
                     /translation="FVFTGQGAQWPAMGAELF"
     aSDomain        21882..22832
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_31740_PKS_AT.1"
                     /evalue="6.80E-83"
                     /label="CAN33_31740_PKS_AT.1"
                     /locus_tag="CAN33_31740"
                     /score="270.1"
                     /specificity="Minowa: mxmal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="consensus: pk"
                     /tool="antismash"
                     /translation="VFTGQGAQWPAMGAELFEYAVFRDTIAYLDTVLAVLPQPAPWKLV
                     DILCGNCDKDLIQKPAVSQTVCTALQMGLVDLLASWSVRPAGVVGHSSGEMAAAYAAGR
                     ITAAEAITIAYYRGYMVSFNQKKGAMLAVGLGADQGAEYVRQAGMEGRVKVAAINSPAS
                     ITMSGDADAIEQLSVQLTQEAIFNRQLRTGGLAYHSHHMLSFGHDYAQAVDDGLQRLAS
                     LGINDTTSRYSNIPWASSVVPQKSSTMPREEVTASYWKANLESPVRFTDAVSKLLDMDD
                     LRIGATVEIGPHPALKGPLGQIVKGLGRTIPHVASVE"
     CDS_motif       22128..22223
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_31740_0005"
                     /evalue="3.40E-08"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="CAN33_31740"
                     /score="26.1"
                     /tool="antismash"
                     /translation="VRPAGVVGHSSGEMAAAYAAGRITAAEAITIAY"
     CDS_motif       22647..22688
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_31740_0006"
                     /evalue="3.70E-03"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="CAN33_31740"
                     /score="10.1"
                     /tool="antismash"
                     /translation="ASYWKANLESPVRFT"
     aSDomain        23073..23603
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_31740_PKS_DH.1"
                     /evalue="4.70E-33"
                     /label="CAN33_31740_PKS_DH.1"
                     /locus_tag="CAN33_31740"
                     /score="106.6"
                     /tool="antismash"
                     /translation="HDLLGARVPGTTRLRPQWRNILRLKDLPWLNDHRVPPHVLHPGAA
                     HIVMAMLAAEQAYAEFPDALPVAGLTLRNVSIKKTLVVPQDDKGIEIVLSMELEDGATA
                     ASPGWASFSIASVVNDSEQWTEHCSGLVKVDVVAFNAPAAIDTTTMDGRAVDAQAWYTR
                     FADMGLQFGPSFQGY"
     CDS_motif       23157..23234
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_31740_0007"
                     /evalue="3.80E-06"
                     /label="PKSI-DH_m2"
                     /locus_tag="CAN33_31740"
                     /score="19.5"
                     /tool="antismash"
                     /translation="WLNDHRVPPHVLHPGAAHIVMAMLAAE"
     aSDomain        join(25305..25627,25708..26230)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_31740_PKS_ER.1"
                     /evalue="2.30E-32"
                     /label="CAN33_31740_PKS_ER.1"
                     /locus_tag="CAN33_31740"
                     /score="104.0"
                     /tool="antismash"
                     /translation="LTSLYFRPYTELLQPLPRDYIDVKVDAVGLNWKDLGLCSGRFDAN
                     NLSNEYCGVVTQVGADVTRLSIGDRVYGMGKGHFGTHTRVPAGLAQKLAADVNAIEAAT
                     MPLVRPWSGSHPAGAVQGATIYATAGTADKVRFLTDHMGVPASQIFSSRDLASLNRATQ
                     QHGGFDVILSTAQGDMLYESVKALAPLGHLVDVGRLDVTSSQTMGLELFQKSAGFTSFD
                     LGLVVERDSVLGAELMQSVDAHFRAGHIGPIKPYSVADIGHLDQTLLQFSQGTHIGKRV
                     IT"
     CDS_motif       25748..25798
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_31740_0008"
                     /evalue="5.90E-05"
                     /label="PKSI-ER_m6"
                     /locus_tag="CAN33_31740"
                     /score="15.8"
                     /tool="antismash"
                     /translation="GATIYATAGTADKVRFLT"
     CDS_motif       26312..26383
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_31740_0009"
                     /evalue="6.10E-10"
                     /label="PKSI-KR_m1"
                     /locus_tag="CAN33_31740"
                     /score="31.7"
                     /tool="antismash"
                     /translation="YILVGGLTGLGRSIVRWMSSRGARD"
     mRNA            join(26524..27462,27492..27527)
                     /locus_tag="CAN33_31745"
                     /product="KR domain family protein"
     gene            26524..27527
                     /locus_tag="CAN33_31745"
     CDS             join(26524..27462,27492..27527)
                     /NRPS_PKS="Domain: PKS_KR (8-109). E-value: 1.7e-30. Score:
                     98.0. Matches aSDomain:
                     nrpspksdomains_CAN33_31745_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="InterPro:IPR020806"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="InterPro:IPR036736"
                     /db_xref="PFAM:PF00550"
                     /db_xref="PFAM:PF08659"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_31745"
                     /note="EggNog:ENOG41; GO_function: GO:0031177 -
                     phosphopantetheine binding [Evidence IEA]"
                     /product="KR domain family protein"
                     /protein_id="ncbi_CAN33_31745-T1"
                     /sec_met_domain="PP-binding (E-value: 1.4e-05, bitscore:
                     20.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MRSAHVDPTRPVRGVFHFAVSYQDISFDKMTEAQFNQGMAAKVFG
                     VKHLHDATASIPLDFFAMTSSLGTVYAFPTQSTYLAANNYLDYFARYRRRLGLPATTVA
                     LGFINDLGPLTNDPVTVNLFVRAKGQTMTGAQVVRMLEPAFVNEQPNALWLGHTDDPLS
                     ASHIVTGIDPAVLAKMARSSAASLASSTIPRWYHDSRVSLMLRALEDASSATSSLSSSD
                     IHASDASPTAQLRRQFDHSVATLRAGGKDSKEDAWTETIKFVTEAIQATVAGMLFVDVG
                     SVNPNKTVAEHGIDSLLAAEFRNWFQGAFGRGDESSVVGEVGS"
     aSDomain        26548..26850
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_31745_PKS_KR.1"
                     /evalue="1.70E-30"
                     /label="CAN33_31745_PKS_KR.1"
                     /locus_tag="CAN33_31745"
                     /score="98.0"
                     /specificity="KR stereochemistry: (unknown)"
                     /specificity="KR activity: active"
                     /tool="antismash"
                     /translation="TRPVRGVFHFAVSYQDISFDKMTEAQFNQGMAAKVFGVKHLHDAT
                     ASIPLDFFAMTSSLGTVYAFPTQSTYLAANNYLDYFARYRRRLGLPATTVALGFIND"
     CDS_motif       26695..26805
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_31745_0001"
                     /evalue="5.10E-14"
                     /label="PKSI-KR_m4"
                     /locus_tag="CAN33_31745"
                     /score="44.8"
                     /tool="antismash"
                     /translation="LDFFAMTSSLGTVYAFPTQSTYLAANNYLDYFARYRRR"
     mRNA            complement(join(27623..27630,27698..28976,29630..29958,
                     30026..30628,30688..30756,30826..30928,30999..31322))
                     /locus_tag="CAN33_31750"
                     /product="Cytochrome P450 family protein"
     gene            complement(27623..31322)
                     /locus_tag="CAN33_31750"
     CDS             complement(join(27623..27630,27698..28976,29630..29958,
                     30026..30628,30688..30756,30826..30928,30999..31322))
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR002403"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="InterPro:IPR036396"
                     /db_xref="PFAM:PF00067"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 113.3; E-value: 2.4e-34)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_31750"
                     /note="EggNog:ENOG41; GO_component: GO:0005634 - nucleus
                     [Evidence IEA]; GO_function: GO:0016705 - oxidoreductase
                     activity, acting on paired donors, with incorporation or
                     reduction of molecular oxygen [Evidence IEA]; GO_function:
                     GO:0020037 - heme binding [Evidence IEA]; GO_function:
                     GO:0005506 - iron ion binding [Evidence IEA]; GO_function:
                     GO:0004497 - monooxygenase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0000981 - DNA-binding transcription factor
                     activity, RNA polymerase II-specific [Evidence IEA];
                     GO_process: GO:0055114 - oxidation-reduction process
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     transcription, DNA-templated [Evidence IEA]"
                     /product="Cytochrome P450 family protein"
                     /protein_id="ncbi_CAN33_31750-T1"
                     /sec_met_domain="p450 (E-value: 1.4e-35, bitscore: 118.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MENMLGYTSMPVPVLVSLALGLAFLLLQSFRYKDPALNPKKPFEL
                     TSTRVKQEYFSNARRLLWDWFTTHSNTPVLLHTDTGKVTILPPSMANEIRNDDRLSFSR
                     WTFEAFHGNLPGFDGFREGSQDSGIVQAVIGNDLTKYLNKVTEPLANETSVAVRELLTD
                     NEEWHTIQLRTVMVALISRISSRVFLGEKLCRNEEWLRVTQDYTTDGFLAAEELRMWPA
                     AIRPIVHWFLPRCRKLRAQVKVARKVMGPILEERRQFKKHLHAKGKQSQGFDDAIEWFE
                     KAAKGRPYDPVSAQLILSVAAIHTTSDLTSQTMTHLVQNPEILEPLRKEIVDTLQQHGW
                     KKTALYNMKLLDSVIRESQRLKPINNASMRRVALKEVKLSDGTVIPKNGMLAVSAHKLW
                     DDDTYENAAAWDGYRFYKMREDPERQTKAQLVTTAPENLAFGHGKHACPGRFFAANEVK
                     IALIYLLLRYDWKLLEGTCDEIKPHCTNCLRHSIECDYSFKPQTNSSSSPQSQQSDSVS
                     PPSQGPSTDSYTFYTSSSVNFQPPKRGHGTPLTSGPDTTQPSPPSNNDLAKRPFQYTAL
                     DMLLFHHFSTSPELTGAQPKARQQLSQIAFSHHYVMHILLAFSGFHLVRRSDDQQWSQS
                     MGFTEAEIYTEAERHFNVAIRDVSATLPHLDRDNSPAMYASAIFIFISSLARGPQPGEY
                     LAFRSDGTPGHLSLFLGVRSVFELCSGDMPTSVFSIHGEGDDSSSRTTPQTEHENSHIA
                     SQNKTKLEDYPHHLETYRALLTTTIPIDDPRLSIYLQTLDRLGHSLDAIMGPDPQGTMG
                     MALFPLVFAWLYQLPDAVVGDLQRREPVALILFAFFLYPLDRLDHVWFICGWPRHILEG
                     IQWHLDGRYRGYIQWAVDHVGGGRLSEGLGVAR"
     mRNA            complement(join(33094..33256,33318..33435,33517..33798,
                     33872..34012,34064..34124,34194..34206,34267..34316))
                     /locus_tag="CAN33_31755"
                     /product="Ceramidase family protein"
     gene            complement(33094..34316)
                     /locus_tag="CAN33_31755"
     CDS             complement(join(33094..33256,33318..33435,33517..33798,
                     33872..34012,34064..34124,34194..34206,34267..34316))
                     /codon_start=1
                     /db_xref="InterPro:IPR008901"
                     /db_xref="PFAM:PF05875"
                     /locus_tag="CAN33_31755"
                     /note="GO_component: GO:0016021 - integral component of
                     membrane [Evidence IEA]; GO_function: GO:0016811 -
                     hydrolase activity, acting on carbon-nitrogen (but not
                     peptide) bonds, in linear amides [Evidence IEA];
                     GO_process: GO:0006672 - ceramide metabolic process
                     [Evidence IEA]"
                     /product="Ceramidase family protein"
                     /protein_id="ncbi_CAN33_31755-T1"
                     /transl_table=1
                     /translation="MASAISPFWGAPTSYLNFCEEDYVITRYVAEFINTLSSFVYILYG
                     IYGLWQLHSRRQTGPRSITYCGLIGVGVCSAGYHMTLKYHTQMSDELSMHLLTTPLLYR
                     ILSFQATPQYTKTVGIILSVLFTIVMVVHMVMDEFLLHAVTFGAAVCLITTRTLKIIPR
                     EIPDVEARKRIQSVALFGCASFIFGYLVWLIDEFVCQSLIVARHAVGLPVAFLLELHGW
                     WHVFTAIGGYIAVAVIDLITSGEVQRDSVAQLAWPLPTVARLLGPAAGETKRE"
     mRNA            complement(join(35156..35527,35581..35693,35757..36535,
                     36630..36786,36842..37052,37104..37154))
                     /locus_tag="CAN33_31760"
                     /product="Sulfatase family protein"
     gene            complement(35156..37154)
                     /locus_tag="CAN33_31760"
     CDS             complement(join(35156..35527,35581..35693,35757..36535,
                     36630..36786,36842..37052,37104..37154))
                     /codon_start=1
                     /db_xref="InterPro:IPR000917"
                     /db_xref="InterPro:IPR012083"
                     /db_xref="InterPro:IPR017850"
                     /db_xref="InterPro:IPR024607"
                     /db_xref="PFAM:PF00884"
                     /locus_tag="CAN33_31760"
                     /note="SECRETED:SignalP(1-16); EggNog:ENOG41; GO_function:
                     GO:0004065 - arylsulfatase activity [Evidence IEA];
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]; GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]; GO_process: GO:0018958 -
                     phenol-containing compound metabolic process [Evidence
                     IEA]"
                     /product="Sulfatase family protein"
                     /protein_id="ncbi_CAN33_31760-T1"
                     /transl_table=1
                     /translation="MRHLVYLLALAGLTTKSPNVVFILTDDQDAHLASLDYMPYVRKHL
                     LDKGTHYRSHYCTTSVCCPSRVTLWTGKLAHNTNVTDVNPPHGGYPKFISQGLNDNYFP
                     VWLQEAGYNTYYTGKLFNVHTVDNYNAPSQLGSPATTFQRDHEIPQSYEGEYSTDVLAQ
                     KAYRLLNEAVTAQKPFFLTVAPIAPHCNVFMNGTGLDANPKFSFSAPIPAKRHEHLFPD
                     VKVPRTPSFNPEIPSGANWIKTLKRQNDTNVDYNDHFYRQRLRTLQAVDELVDGLFTRL
                     KEYNILDNTYIVYSSDNGYHIGQHRLQPGKSCGYEEDINVPLIIRGPDIAQNVSTDIVT
                     THTDLAPTFLELLGIPLREDFDGNPISLTRSQIERAQEERQEHVTVEYWGYAAGEGIYD
                     FDLSAYNNTYKALRIKGIGYNLYYSVWCNNEHELYDMTTDPHQLHNLLSAIEQPSATSH
                     TILNVDLSKVVQRLDSLLLVLKSCKAQVCVKPWDALHPRGEVMTLKDALDVHYDHFYEV
                     EQTTRVQFNECARGYFLDAEGPQFDSGTDYEVLRDGLPWYEWV"
     tRNA            37868..37941
                     /locus_tag="CAN33_57575"
                     /product="tRNA-Ile"
     gene            37868..37941
                     /locus_tag="CAN33_57575"
     mRNA            40172..41692
                     /locus_tag="CAN33_31765"
                     /product="major facilitator superfamily protein"
     gene            40172..41692
                     /locus_tag="CAN33_31765"
     CDS             40172..41692
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 97; E-value: 1.5e-29)"
                     /gene_kind="transport"
                     /locus_tag="CAN33_31765"
                     /note="EggNog:ENOG41; GO_component: GO:0005887 - integral
                     component of plasma membrane [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="major facilitator superfamily protein"
                     /protein_id="ncbi_CAN33_31765-T1"
                     /transl_table=1
                     /translation="MTSKSAGLSAAEPIFPQIPRVALVPQDDASSPLSSLELHSIEPIG
                     ANTPHSRRTRHAGSTKPSEVDEMFNVVQSAAAENYGAQDTNRKTASIHPRRNTIWRLAS
                     ACLMNFGNGMNDSAPGALIPYIEDDYGIGYAIISLIFIANAVGFVLAAPLTHTIQVRIG
                     HAKSYALSMSLVTAGYVAIVCHPPFPVVVTAFLLLGFGMALSIALNNVFCANLNSYATA
                     LGFFSGAYGIGGVISPLLATAMVSHGIRWTYFYFITLVISTLNMLLAAVVFRNYKDEGA
                     ASRAPTQQTSPSLASQTAQPNENDSHNSHTRLQTLKRAIRNLTTILGSLFIFAYQGAEV
                     SISGWIVSFLINYRGGDSRRVGYVSAGFWAGITLGRFLLVYPANRIGEKLAVGLLVVGA
                     IAFQLMTWLIPNIVGEAVAVAVVGLLLGPMYPCSTAVFAKLLPRSIQLTSMSFITALGS
                     SGGAVFPFLTGILSQEVGTIVLHPICLALYAAMVVCWCFLPAISKRSE"
     mRNA            complement(join(42861..44175,44231..44298))
                     /locus_tag="CAN33_31770"
                     /product="major facilitator superfamily protein"
     gene            complement(42861..44298)
                     /locus_tag="CAN33_31770"
     CDS             complement(join(42861..44175,44231..44298))
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1137:Major
                     facilitator superfamily MFS 1 (Score: 229; E-value:
                     1.3e-69)"
                     /gene_kind="transport"
                     /locus_tag="CAN33_31770"
                     /note="EggNog:ENOG41; GO_component: GO:0005887 - integral
                     component of plasma membrane [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="major facilitator superfamily protein"
                     /protein_id="ncbi_CAN33_31770-T1"
                     /transl_table=1
                     /translation="MNAPASAEQHPPTEAPKNKHSRRQYVLIVLSGFMLNFTGCGVVFA
                     YGVYQAEYEKMATQKDTAFTGSSSAEITLIGSLSSAMMKLGAPFVVAWCKCFGPRIIVC
                     VGGLIFGLANILASFGTASWHFQLSQGLLLGIGSCLSYMPSMIVPPTWFSKRRGLALGI
                     ISAGTGIGGLVFAPVIQACIDTMGFRDTLRLVGCLSALLICASGAVLVWEPAMEQRLQE
                     EVAAKPSLVSRLFQFPLPPWSLVRQRKFIAQVLNAAFQSAAYYTPIYYISSYGQTLGYS
                     ESEGANWTSLSNACNAIGKVAIGYLADYIGRLNSFFLVTLLSAVGAVALWIPSTLLGST
                     LHDLVAAKGCFIVFTIFYGLFASAYIGLFSPALVELFGLQEMPRITGIMYMVQGAAGLV
                     GTPVSGVMVRTYNGETTSRSYLDMAIFVSALIVASTMTVAWARMEQGFDRVSGHLTWKW
                     KL"
     mRNA            45344..46300
                     /locus_tag="CAN33_31775"
                     /product="Pyridoxal-phosphate dependent enzyme family
                     protein"
     gene            45344..46300
                     /locus_tag="CAN33_31775"
     CDS             45344..46300
                     /codon_start=1
                     /db_xref="InterPro:IPR001926"
                     /db_xref="InterPro:IPR036052"
                     /db_xref="PFAM:PF00291"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081:cysteine synthase (Score: 262.9; E-value: 5e-80)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_31775"
                     /note="EggNog:ENOG41"
                     /product="Pyridoxal-phosphate dependent enzyme family
                     protein"
                     /protein_id="ncbi_CAN33_31775-T1"
                     /transl_table=1
                     /translation="MSLIPSVDSALDAIGNTPCVQLTRVVPQDCARVFIKLESLNPTGS
                     YKDRMALSVIEEAERRNDLRPGMTVVEATGGSTGSSLAFVCAVKGYTFRVVSSDAFAKE
                     KLNTMTAFGAHLDIVPSENGKITPQLIPSMRERARRIATEDKDPSSYYYADQFSNPDVF
                     PGYETLGREILAQVGEPIDAFCGAVGGAGMVMGVGKTLKQSWPACHVAVLEPASAPALT
                     KGHGGEHSVEGIGIGFPPPLLNKDWYDEARAIDEREGRSMCRRLAREEGLLVGTSSGLN
                     VVAAIQLAKELGPGKTVVTVGCDTGLKYVRGNLYTDS"
ORIGIN
        1 atgttataag tgaaagtagc ctctgacagg tcgcacggcc ccttgagttg gtaatgcatt
       61 ccctggtatc cttgctagtg cattgggatc agactcatgc gacaatgacc taacaactac
      121 atgggccgcg atgtaacgtc actaatgtcg tccttttgtc aactgagacc ggaacaccta
      181 ttcgctagct ttttaaaaag gagaataacg cgttgtgcga gaagtgacag tataagggtc
      241 gctacagcgg caagatgcac ttgggaatct cagggacctt gaaacacata acccacgatt
      301 ccatgatgat gatattgatg tctttcttga cacttgctgc aactgcctta acggcgccat
      361 cgcttcacat ccgggaagac ctcaggtacg ttcgagtaac agtgcaacaa cataagatca
      421 catccaagca gattgtggtg agagatagct ctactgaaat atcatcggct ctgcctgctc
      481 aaatgtcttg acaaccggag tgtttgccga cttcggtatc gtcgcagatg ttgggtctaa
      541 cggcgatggc aatatcactg ccgggacttc caccttcagc gttcatgaga atccccagta
      601 ttctggtggt atcacttttt acagaatgta caatgataat gagtcactca tggtgtgcga
      661 tggcgttcct ttgcccagca ccgtccaatt gaacccagtt aaagtgggcg acatatcccc
      721 ttgtttcagc gatcaagtcg acataacttt acagcgagca gcggagactg tccacgttat
      781 ggacactttt ccaatgcctc gtcgtgaagc aaattccact gacgctgtgt ctatgagaaa
      841 tttggagcag cgacaaaccg gcgcgtgcag aatgtggtca cccgctaagg aaagttggag
      901 acggcgatcc ccatcagaac tattggcgga aacagttggg cgtgagccga taatgcactt
      961 tcctttggtc tggtgctagc gactgatgtg cgacgaacag gagaatctgg attgcgggag
     1021 cgcacactat tgcactgttg gcgcatctca gtcaaagtcg tatacagttg gatggacggc
     1081 tactgcagat gcatcacaat ggatctctgg cggctttgcg gtgcaagcga gctggacaac
     1141 cgggcttgac tatcaatgca ctgctagctc ccatcagacc gtctgtatct ggtacaacac
     1201 cgctcatact gcgtacactg cccaaaacgg actttacaac gtgtgcacgg ggttcaaccc
     1261 caataatgat gccggcttcg tcatgttctc cccaaaccag aacaacaaag gcggtggatt
     1321 ttattgcgtt attggcacat gccgcagcca ggggcagaat tactgggaca agagtggtcc
     1381 tgcaggtggg ccttgactga tttcaactgg taccaatgat ggtggacatg agacttatta
     1441 ttgtgaaggg agtgtgttat tagtggatca gctgtattag aaaatgtttt tctctgatta
     1501 agtcttggca aagaagtctc atgtcttagt tggtctgaag accacagtct caagtcagaa
     1561 tcaggcttgt gaaagcgtat gcaccttcct gcttccatgt cctggttcac agcctctcgg
     1621 acagatgcaa cgggacacaa gtccttacgg acggagctga tatataaaga caataggtga
     1681 gaataatcga tcacaagtga ggttggactg cttggtaggg cagtcacttg ttcggaccat
     1741 tatcagacga gagggggtat ccactaggaa ccgaccgaat agtagggacc cactagagag
     1801 gagggaccaa ctcaagatca tgagctccgt ggagggtagg aatccactac aaaggaaacc
     1861 actatattcc agagccatcc gagtatagga ccggataaag caaggatata cggagagtca
     1921 ggtggcacca aacagtagaa tagagaccca tcgcaattat ggaccgacta aaatgctcta
     1981 cttccgataa gatattctac ttgtcttaaa ggtgtccttt ttaaggcagt tctttctatt
     2041 atcccgactg ggctcacgaa atgtccgtag gatatgcccg atttgatacg gcgcagtatt
     2101 gttttgtggc tgtacatact gattttgaat cttgcttatc gttctgtggt catgtaacct
     2161 tatgtcctaa aggcgcttaa ccgaacggct tgtggcgcgt ttgctaaact cggaaggtgg
     2221 atttaatcgc gggttttgtt tagcgcgtgt tcggttatca agcatcgata actattgtaa
     2281 ggaaagacca tatcgtgtag ggcggtccaa aagtggagct gatacattac agaccctcag
     2341 acagcattag cagtataggg aaagcctcat aattgatgtg aacattggcg catgctaact
     2401 ttgagtatga ccatggcacg ttcacccacc aaccctacgc gatgtggggc aaaataatag
     2461 aacatagcag tttcggaatt tcccgccagg tgtctttctc gcatttcccc ttggaaagca
     2521 ccgaggcagg accatctggg tggaggatgg gtagatttag gccgttctac ctgccttggg
     2581 caggtagcga taacaattaa cgtaaacctt ggggtatttg tctcaacgaa ccctgtattg
     2641 ctgattttca gcacactcag tcgggaaagg atctcacaca gcagatgctg aagttctttt
     2701 ccggtacagc tgatatagct aggtttatga aactttttat tgagtatagt aatctgtcat
     2761 tcgtacctgc ggacatactg tgatataatg aagtacaaaa ttaacagtcc gtgactcagc
     2821 gacagggcca cctctcctcc gttactccat cccatgtaat tccagatact tcgcacaagt
     2881 ggagtaacca ttgcgatata aggtaggcta aaagattagc ttcaaaaatt tggaaagcat
     2941 taatctaaga aatcatactt acgtccacgg actttgcacg atattccgaa gaacagtaac
     3001 ggttcgcgaa ggtgttgccg aagaggagga gtgagaaatt gacgtcgtgg ctttttcatt
     3061 ggtacccatt ttgttttatt cgacagtaga aaatattagc accgctggag gcaaggatat
     3121 attgtgtgga acagttgcac ccaggtacct aatggtagat gattagaagt ccggtggcta
     3181 cttcgaggta tttatgtacg aaggctagcg ctaaccccac tagctttgca agggttcgta
     3241 ggccggctat caactgttcc ccaactccac atcggagacc catggttcct ctcatactaa
     3301 aagcaccatt atttcaatag ctcattttta tgtgggtagc cattatatta tgtctcatgt
     3361 gcaaaccgta caattcaaag tcttgtatgt tctaaggaga atcgctcaac accaacatac
     3421 ggctataaat atggcgtagc gaacccccca aaaatgattt cctaagtggc acaaccatct
     3481 taaagcatca gcatgaaact ctcaaccttc ctcttctctc ttctggctac aagccaggtc
     3541 actttagcga caccaattcc aatagtggat gttgctgaac ttccttcaga caccggtctt
     3601 gaaatccgat ctcctaaccc ggctgacgag ctgctggcga ttctagagca gcggaatact
     3661 agagtctgtg agatacttaa tcgaacgatt cgttctattg gtaccagcaa atttacgtat
     3721 ggcgcatgct ctcctctcga tcaacaataa tcctcaaggg actaataatt tctagggtcg
     3781 tctatatcgt gatgggctca cgtcttgctc gacaagtctg tgaatatgcc ggtggcagta
     3841 gatgtgagga aatatcttat attatttcag acggtctcct cttggcctat gttgctgccg
     3901 cccattactc tggagccatt cccgaaggtc taccgggtaa gcgtgacgtc gatgtctccc
     3961 aggattattt ccagctgtgg gagactatgc tgtcaagtaa tggagatatc tcctatgatt
     4021 atctcactcc tctctcgaat acctcaaata ctcttccctt ggttagacgc caggatcagc
     4081 ctttaccgat ccacagaatt cagatcactg gtttcgccca taataactct ccgaagcacg
     4141 atatcatcgc caatcactat gaaaatggtg acaccgttct tcaacttcct cttgcaggag
     4201 gggttcctgg tgctaatgac actgaaggac ttgatttgag gaagcggttt gacaacccgg
     4261 ggtttaagat tgcgttcact accaggggta gatcacagct cactcaagcc catcaaaagt
     4321 ctatggcact ggcaggagct gctacatggg ctgtctatgc agacaatgcc aatcacaaga
     4381 tggatgactt catcggtttt gctgagactg atcatgcggc taacttctac taccgaatca
     4441 ttccggagct gagaggattc ggaactaatt acgagactgt tgatatttgt gggggaatgg
     4501 catcgtactt gtgaagagat tcggcaaatg gtgaggtcgc tgtcgtggat atgaaccgat
     4561 catgcattgc ttgtcaatgc atccatcatc gcactgacga ccagtgagga agtgatacgt
     4621 gcacgaattt atgaccacat atggaaagaa agaaatgaag gtcatattac cgataaggaa
     4681 aaagttgcta gggtcagtgt gggtacgggc tcagttttca tgcatgaagg gcagtcgctt
     4741 tggtttgcaa ttgacctgac atgcatcatg tatgatataa atcctcatat taggaggtgt
     4801 gagaagggaa aactcctata ctactaagac cagaacaaga ttataactaa tttaaatcct
     4861 atatgaaaac cttttttcta ttctccatat ctaaacaagc aaagcaacac ccagagtacc
     4921 agtatatacc acataattcg cacatacaac ctagtataac aacagcacta agcattaagg
     4981 ccgatgccga tcgcttgtgg cttcccgccg gtccctctcg cgcactggcc acccattcaa
     5041 accagagaca acagctagga agtgtctaga taaaacttgt ctaatgcatt ggctataatt
     5101 ttaatttttt ccgtaggtat gagatgggca gatatgcgac caagaggggc atgaagtgcg
     5161 gagttgagtc agtctgttga ggtaggttaa atgagtctcc ttctggtaga cacttcactc
     5221 gagtctgtcc ccgtgacatc tccttcggag tctagtcttt tcatctcgct gtatcagaaa
     5281 cgaactcaat attgataaga ttacaggtat ggtcttccct gaccttccct gaccatcaca
     5341 gcagctgatg attccctatg acacaggcgc tgtggggacc ggccgtacta actagtagac
     5401 gttagtactt agtagagatc aactaatcca taagtgtaga gctgacactg cgccagttct
     5461 acttagcgtg ggggcctttc cagaccccag tgagttgtca ctctatttat gccggatcac
     5521 ccgagccatg atccctgctc ttctccaggt ttcaaattcc tagattcagt ctgtccttcc
     5581 acctgcccct ccgcaatgac cacaatcaac ggtcactgcg atccggcctt caccggggtg
     5641 cgcgatctcc tacagcaatt gatcaacaat gaagaagagc taggagcatc catctgtgtc
     5701 aacatcgacg gtcaaaacgt cgtcgatctc tggggcggcc acgcagaccc agcgagaacc
     5761 aagccatggg aaaaggacac actaaccgtg gtatggtccg tttccaaagt aattaccgcc
     5821 atcgcaacca acattctcat cgaccgtggc ctcttagacc caaatgagaa ggtctccaaa
     5881 tactggcccg agttcgctgc gaacggcaag gagaatatcc ttgtgtccca gatcctcagt
     5941 cacacctctg gagtatcctc ctgggagctt cccaacacct tagacgacat atacgatgcg
     6001 aaaagaggag ccgataaact agcccgacag gccccctggt ggacgcccgg cgaacactcc
     6061 ggctaccacg taaccaacca gggccactta ctcggcgagc tggtgcatcg tgtaaccgga
     6121 aaaccgttgg atgagttcat ccgcgacgag cttgccagtc ctctggctgc ggacttccag
     6181 ctcggggtcc cagagaagga ctggccacga acagcagacg tttccccgcc gccgccactg
     6241 agtctcgacg gcgttgaccc gcagagtgtt atgttcaaga gctttgccag tctgcctata
     6301 ccggcggaag aaagtatgag tcctgggttt aggaaggcgt tgattggtgc cacgaatgga
     6361 ttctctaatg cccgaggcat tgcgcgcatt gcgtcggtca tttcgcttgg aggcacggtg
     6421 gatggaaagc agtatctctc gcctgaaact attgaccgca tgctggagga gcaaataagt
     6481 gggccagatt tggtcttgat gtatcatttg cgttggggtc ttggtgttgg gttgcccgtc
     6541 ccggagactt ttccttggtt gcccgacggt cgcattgctt tttggacggg ctggggaggt
     6601 tcagttgttg ttatggacct ggagaaacgg atgacgattg cctatgtgat gaataagatg
     6661 ggacaaggca cgttgggttc ggataggacg gcggcttatg tgcgggctgt ttatgattgt
     6721 cttgcataga tagtatgtta aggctcgcga atggaacacg atatataaac tgaaaatagt
     6781 caagcggttc aaagtctgcg cccctccatt gcgaacactg attagaagta gtaggctgtc
     6841 ttgagttctt gtgtagaaca tagtggtttg gcaggagaag tttcatttga aaaaaaaaaa
     6901 aataaaaaaa taaaaaacta aaggtgtcta cgttcgttgt gactgatggg gtggttgtac
     6961 gctgccgaaa aaacaaaagg gcaaaaaaga atgaccagac tggggctcga tcccaggacc
     7021 ttatcggtgt taacgatacg tgataaccaa ctacaccatc cggccaattc aatgaaagta
     7081 actgtcactt aaagactcat tatcctataa aaacgattcc gagaagttct tgttggttag
     7141 cataatcgtt gggtcggctg tgctgattta ggctgcgaca tagcggtatt ggataagatc
     7201 ttcacgccgc tctcctgagt cggatccagg cagagcttta atcggtggga aagattcaga
     7261 gctctttcaa actaagacgt aatgcatctg taagtttgta aacattgaca tggttcgaat
     7321 tctcaaggtc tctaaataat tccagacttg gaagcgctcc aactgagatt aagctcaggc
     7381 gattacccag accgccgctg ttagcataag acacgatatg acgggctttg aaataatacc
     7441 tttagcattg tatccaagat actgatctga attatgaata aacaatatcg ggtttcagtc
     7501 tagcaggttg accttactac ttcgcccgag tcataagtag attcttcgtg acctcttact
     7561 tggctctcat ccgttctatg cttcgccctg gcaagacttt agctatagtt gcactaagct
     7621 atacaattga tgctaggtat tatgaatcag tagatgaatc aaaggctcta agagtacata
     7681 aagatataaa ttctacatgg gcttttggta catgggtata atttgggcgg cctcgtagcc
     7741 taaggcagag ttgtgcgtcg tcagctttta gcgcgccgaa ctcaaccaac tggtagtagt
     7801 catcctgcgc agcacgtcag ccttgtgtac ttggtgcctt ctactcatca acttagagat
     7861 ccccggaagt gctactcgac taaacaagag cagattctct ctagtcggtg aaggcacctc
     7921 acgatgtcgg gaaatgacgt accttcttac gatgagtttg ccgtgggctg gatctgtgcc
     7981 ctaccactgg agatgaccgc agctaaagcc gtcctcgacg aagaatatcc aagtctacat
     8041 ttacctaagc agcatcacaa cacctacgtg cttggaagga tttccggaca taaagtggtg
     8101 attacatgtc ttccattcgg gatttacgga actacgtcgg cgactgcggt agttgagcag
     8161 atgctattca cctttcggtc catccgcttt ggcctcatgg tcgggattgg cggaggagtc
     8221 ccgtctgctg tcgatgtcag actgggagat gtggtcgtaa gtaagccgac tgctggcctt
     8281 cccggagtga tccagtacga ttatggcaag accgttgctt caggtcgctt tgagcagacc
     8341 gggacactca acaagccgcc gatagttctc ctatcagcgt tgtcgtcgct ggaagcagat
     8401 cgtctggctg gaggcagcga cattggtacc tatgagaaga ttatcgcgga ttctctaagg
     8461 gctgccaaag atccatccgt gtttcggtat ccgggtgccg aacatgattg gctcttcgat
     8521 gcctcctatg accatgatcc tcgcttcgca tcctgtgctg agtgtgaccc agaacgacgg
     8581 gtgagacgca agcctcgacg ctcatgcaca ccggtcgtac attatggcaa cattgcgtcg
     8641 ggcaatcaag tcatgaagca tggcctcacg cgcgatcgca ttgcgcagac aacacagggg
     8701 atcttgtgtt ttgaaatgga ggcggcgggg atcatggatt accttccgtg cctcgtgatc
     8761 agagggattt gtgactattc tgactcccac aagaagaaag agtggcaggg gttcgcggct
     8821 ttgacagccg cggcctatgc gaaattgcta ttgtcgaaga ttcctgtcca tcggagtgag
     8881 gcgtctacgc tgatacaggc acctggttcg aagaatagta gtacgtgggg cccaagcatg
     8941 gtgtacttta tacccagaga gctattactg atgttaatga aggcgattcg ttcgatgttc
     9001 gcttcgacac aatcgaaatg ccacaggctg ccatttctgt gggccgggag gcagagcttg
     9061 caatgataac gaagagtctt ctatcagaca aatttcgagg cattgtcacc ctatatggaa
     9121 tgggtggaat tgggaaaacc gaactctcga ttatgtacat catgcgccat cggcaaaagt
     9181 attcatctgt cttctggatt gatggtagca gtcttgacaa gttatattcc agctatacac
     9241 aagcggcaat gcggatcata catgatcatc caggtgacca gtctttgaga aaggccttga
     9301 aggaaggtga tcagattcaa ttggttggat cagtcaatga gtggctgagt cgcccttcaa
     9361 acaatcggtg gttactcata tacgatggct tcgaccttcc tatggtcgaa ggttttgaca
     9421 aagccgaaat catgaaaatg agactgcctc caagcaagca gggtcatatc attattacaa
     9481 tgagaagtta tgatattgga ataggtgatc agattcaagt aagaaagctg gcagcaattg
     9541 atgacggcct cgatcttctg actcatgtgt gcggacgacc gaatctacga gatggcaagt
     9601 aacccgtcgt ccctgctatg catttctatt aacagctgac tggtactact tagaccccta
     9661 catcgcagaa ctattaactc agctagatgg gctgccactg gccatcgtgt ctgctggggc
     9721 ctatctcaaa cagagtgtga taacttgccg cgagtatctc aaattatata aagaatcttg
     9781 gctgcagtta caacaactat cgccgcagca atcttcgctt gaacaaaagt caatgcatac
     9841 aacgtggaaa atcacactaa accagattat gcgccagcat agacatgccg ccgtactgct
     9901 taagcagtgg atagctttta atagtaacga tatctggtat ggcctcttcc agagtgctcg
     9961 accagaatca gcgtccgacc ccttagtgtt cgatacagca atggctgtgc taagtaggta
    10021 tggatgggtc gaaccagggc ctgtcgcagc aggaaattct cagcagggtc ggggctatag
    10081 ccttcaaaaa tgcattcatg cctggcttca atacgaggac tgcttcgtgt cagatattga
    10141 cctgctaacg cagcttgcag ttttgaagat cagtacttac cagttggatc tggtcaccaa
    10201 attcaatttt ttctcactgg aactccctga tagaaaccgt cttcttcctc atgcagaccg
    10261 atgcctggaa atctatcttt ctagcggcaa ggataaatac aacagcctct ttgatctgaa
    10321 agcgcagtta cgacttgccg atttatatat gatttggagt acccgggcct cacccatcta
    10381 tacttgctat cttgatttcc tgtgccagcc atatgaggaa aagcgaaatc tggccaaatc
    10441 ccaggacctc tactgtctcc taatggaaaa gcttgatatg caacaggatc agtcgaacag
    10501 ggaagtgcaa gatatgatgt ccaaggtgta tcaccagcgc gggcttatca tgtttcgcaa
    10561 ccagcagttt gtcatggcca gcaagatgtt tcgattgtct atccatagta acgctccggc
    10621 ttatgtctca catataaagc tgacgcagtt tttgagcggg ccaatttttc ttatcccact
    10681 aaatgggctt atcttctata ttttacttcg agaggaagac ttcaggaagg acgtcccgct
    10741 aaatatgttg ctgctcttcg tgaaaccaat tgtgtttctt cacttattga tatctcaaag
    10801 gatgcaacgg tggaaaacct tgttgctgtg ggcagttggc cacgcctgtt tccaggtgta
    10861 ttactcgtca attcagccta cgcttaattg gggggctttc atctgcggaa catatggaga
    10921 ggtagcaatt gtattgctgc taatgccaat gctcttccgt gaggggattt attaatcctt
    10981 ctctttgatc cgccccgcag agacgaaaaa gcgaaaaata cgacgtacat tgtggctaat
    11041 atgaagcatt tgcgtgtaaa ttagcgtgat atatcttctt tcccgctcat acctttcata
    11101 tttgagccat accatattca ctcaatttat accctagcat cactttattt tcctctatac
    11161 ctccaccccg gacaagatat ctacccaaac aacctctccc tcctcatccc cagcgaactc
    11221 accaccccca ccgctccggc caccaacgga ataataaacg ccctggccat cgcatccgta
    11281 atagccttga tagcccgatc cctcaactcc ccactcaagc tcttcaacaa cgtactctgc
    11341 acacccgcta cagcattccg tatctccgcc tcactatatc ccctcccatc caacacccct
    11401 ttcagattct ttactgcagt agactgaaac acctgacttg ccaccacaag acagataact
    11461 gtagctccaa tctgcgccac attctgcaaa ttgatcgcgc tgaagatatc ctcgggaggc
    11521 accttgagac tagctaccgc ataccccagc tgcatggtca tgccggtgcc gacagccatg
    11581 aggatcgtga aaccgtagat ctgtcctgcc ggggtagagg gtgagaggta tccgacaaag
    11641 agggcgctgg cgagggtgag gaggatgcct gagatgaggc acagcggcat gtaatatttg
    11701 gcttttggga ggagccagcc gatggcgagg ttgatggtga tcgttacgag gaggtagggg
    11761 agaaggcgca cggcagccat tagggaggag tcgttgcgcg tgaactggaa gtagattggg
    11821 atgtagaagg tcgtgaagaa catggcggtg ttggcgcagg tcgttgtgat gtagaggagg
    11881 atttgggtgc gggagcggag gagatggccg gggaaggagc gcgtttgggg cgtagtgaag
    11941 atgcataagt attgttggag ggcgtaaagg atgaatagga cgccgaagag cacgattagc
    12001 gcgatggtgg cgccggagtc ccacgcccag atgcctcctg cagagatgaa gccaagtgcg
    12061 aaggtcaccc acattgccgc gctgaggacg aatcccagat agtcgagtcg cgttaagcgt
    12121 ttgcgaagag attggcccgc gccggggtga atggcgggga ggtagaagag gtacacgggg
    12181 gctgtgatgg cgccgattac caggttcagg taaaaacccc agcgccaggt ggcggaggag
    12241 tcggagaatc cgcctcccac gacgggaccc aggatggcac ccacgcccca gacaaatccg
    12301 gttcctgtaa gataggtgcc gcgctcgttg cgggtggtca tggcagagaa atggttaagt
    12361 ccaccgagat agattcctgt acctccagcg cctgcaatca cacggccgac aataagggcg
    12421 ttcatatttg gagcaccacc acagagagca gaaccacctt ggaataacac gattccagca
    12481 atgtagagcc acttcatatt catgacggta tagagaaacc cgtaggggag aatcacggca
    12541 actgaaccga gtgggaaacc ggctccaatc catgcaagtt gcgacacgtc cccgaatctc
    12601 tcaatcacgg cgccctgcac atccgcagcg atggttgtat caagtccata catcagagca
    12661 gagagataca gagcagcgca aatcagaaac catcggaaac cggtaatctt gcggacatca
    12721 tcatcggtgg cactggcgtc ggcgtcatgt cctttctcat cggactcttc gcgatgaggg
    12781 agatgattat tcacagcgaa gtctgattcc tgactcgagg gcagtgaatg cgctgcagct
    12841 tccattttgg cgaacccgag agggctattg tttctcgttg ggaggactga gcggctgggg
    12901 aggatcgcgc atatgtatag tgtcgagaca gggcagatca cccattgctt ctccttatgt
    12961 ccgttatgac cggcggacca cgtcgtggat taaccacgcc agggacactg caggacaaat
    13021 agtctctaaa aacgaagctc tagtgcttcc acgatggcgg gattaggagt ttagcattgt
    13081 ctatccccgt gggaggccgg gggatcatca tataacaaac acgtcgctca cccgaaattc
    13141 gtcggccgaa gatagaatgg cccacgcact cacccgacaa agagcacaat gcatccgaga
    13201 tcaccccaac caacaaccgg agcacgcact ggctccaatg caaattcaaa actcatggat
    13261 tattgccaaa atcctgcccg atggcaaaat gcagatcgtc gaccggcccg aaggattcac
    13321 actggataca gctctcgggt ggcgcccatc cacgaaacgt aggtagcgat ttgcttataa
    13381 gcttagaagc ctttcattgg ggttgatctg aacctaacag aaaggaaaag aaggggattt
    13441 tgttgtggct aaacacacag caagaagaag aaaaattacc tgctaggtcg acacagggct
    13501 acgtttcgat gatcagggtc tggaacatgt atactaatgt cgtactattt tctctcatca
    13561 ttactggaca atacgagtag ccaatttaaa ttgcatttca aatatcctga gcaaactaag
    13621 tgcgctgggt acagaaacat tggcctcggg ttgcagcgcc tgcttgttat gcgcttaccg
    13681 ggatctcaga cgcaaatatc ccttcttggc gcggtaggag atgtcgtagg ttgcctcatg
    13741 accagccaat gcctcaggta catcgagaaa atcaaacttc caagtcatca tgacagtcat
    13801 gatcctcatc tctagctgag ccagtcgccg cccccagcaa gcccgaatgc ccagcccgaa
    13861 cgccaactgc gggtacgacg agccatcaaa ctcgagttca ccgcgctcat tctggactag
    13921 ccaacgctcc ggatcaaatg cctcaagatc agggttacca ccacctgggt acttccgggt
    13981 cgtcttcacg tcactccagt acagggagga tggcgaagag gagtagtccg gtccctgaca
    14041 gacgagaagg acgaccgtgc ctttcgggat ccggcggccc agaagctctg tgtcacgggt
    14101 agcgtcgcga ggaacaagca tggcagcgcg aagccgcaag gtctcctcca atactgcgtc
    14161 caaatacggg agtcggaatt ggatgatctc agctgcagtg ggtaggcgac cctcttggac
    14221 tgcggccgcg catactgtct gcagctcgtc gcgaagcctt gtctgaacgg caggatgctc
    14281 agccagtagc ttgagaatcc atactagcgc cgcactggtt gtgtgttggc cggcaatgag
    14341 atttccgtat gcctagatgc aatgacccgg tgtcttagta gagatttcag aggccgaaag
    14401 aagctgttta cccacctcgt caatcatgat ctgtttgcca tacataggct gccggtcggc
    14461 cttgcgagat gccttctgct ctctatacac catatagtca ataccagtct tagcctcttc
    14521 gtcgttgccg aagcgctgca gtgctaggtt aatatgcttg cggataaagc gatctttgcc
    14581 gacgaagaac ttccggtaat atggggacat gtaccgtgcc caccaggaca cgatggaggg
    14641 aggccattta gtcgtgtaga tggcagccat ccggtcaccc acatcggtta aaccctgttg
    14701 gaatgggtgc aacgaggcct gaggaaagat gacgtcggtg tgcttcccaa cccctaactg
    14761 agagttgtcc agctgctcga caaactcaat ttgcctacgc agagccgagt cctggaagtc
    14821 ttgtccgaag tggaagcgca cgataacatc aagagctagg gttttcaggt cggccagcat
    14881 actgaatggc cttccatttg ctacccgggc tttggattcc caaagatgga taaggttgag
    14941 caccgaagag tggatgatgg gacccacggt ctggtgcaga tagtgcggag ctagaaggtc
    15001 tttcaaccag ctgcgggagg ttctccagga gtccccagtc ttcatgttaa ggtggaactc
    15061 tccaaataac gggaaccgat cgataatgta agacgatcgg tcgaagtcac ttcgtcccat
    15121 cagcagctcg cgggtctggc cgacgtcagc cacaaggacc accggcttgg agagcgggcc
    15181 catcagcgcc tggcatatcg gagacccatg ctcctcaagc tgcttgctgc accacttagc
    15241 cagtccggca ggatcgcccc tcagagcagg cacgtcgccc aaaattgatg tagcggcctg
    15301 cttgttgtaa ggaattcctg gtaatgggct cgggagaagc catcgataaa ggacgtataa
    15361 ccccaccagg caaatcgtaa tcgagaagac agcagggtat ccatgaaaaa gctcaacaaa
    15421 gctggcaatg taagaaggcg ccattatgtc atgcgaccga tgaattttgt atttccaata
    15481 ggatttggac aaggtaggca atatccaatt taccttccgg acggctgttc tgagctaaat
    15541 attcatggat ctttgaggcc aagtataggc ccttaatgct aatactaatc atgtcttcgg
    15601 aataaccaac aacgaggccg atgttctttg gttcatggat cataaccgta tattcctttc
    15661 ggccatcatc gaaggttaga tactgatttg gaaagccccg cttccttctc agccacgctt
    15721 gcagtcgagt gccaatgtaa gaagggagtg atgtttcggg tggcgggctg tgttgaaagc
    15781 tcgtccgaaa tatgtcggac gcacctctac ccgttaattc accccacgga agcgagcagg
    15841 ttcgacctgg aatgtagtca gactacgtga atatctcctt ctccatggtt gcgtagacac
    15901 agtggccacc ctccacatct acaaatggca ggtgcaggag ttccgaatcc gttaatgtaa
    15961 gcactagcag tccatcgaac tgtatattcc gctaacaact atttactgct tatcgggttg
    16021 atgcttcacc ggaaaatcca agtgaaggaa gacctgctac gaatcacgaa cgccagcctt
    16081 gaacgggtgt ccatatcctc gccggcagtg attacaagcc tgactctgct tggaggaaaa
    16141 taattccact ttacgagtgg aaattgccat tccaagacgt gaggtctaga gagggaaatt
    16201 gcagcattga gtatgagtca ccgtgcgcta ttgtggataa catgtctggc atcaaggtcg
    16261 gatcctctga agacatccag agtccagagc cgtcttctag gttgaggaag ttcgaaagga
    16321 tggctggaga tgaagagctc cggcttgact cattaggtgt atatggctcg agggaatgct
    16381 ccatcctggc agccttcgca aaaagctgcg tcacaacctg tgccccagag gcagccattt
    16441 cgctgacctc agctaacatt tgaagacgtc ccagggcttt ctcaaccgcc cgcattgccc
    16501 ggggccgagt cagagtggcc actcttaagc cgagaatatc gggatgatcc tcgccttgat
    16561 caaatggaaa gtctttctgc gtacaaagta tcagaagaac aacggcggct tcaaacgtgt
    16621 tgaatatgat ggcgctgaaa cgcgtgtggg agcctccaaa catgatatgc agagctgtga
    16681 cggcatccag ctcttccaga gcggccagag ccagcttctg cttctgcgat tggagaagaa
    16741 cttgcttata agggggtaga ctggtgactt ggcctggttt cagcaacagt aaaggacgaa
    16801 aattccaaca gactgaatcg aatatggcaa tgtagagcag ctgtctctgc atgggtaatt
    16861 taggaagttg gccgtcccac ctccgatctg gattcagtgc ataggctggt ggtagggtag
    16921 ggatatactc tgcgcagaat cgctcatacc gctgttcgcc gtgagtaggg tcgtacggta
    16981 ggttccgtct ggaaccgaag cttctccaga atctgcccag ccggacttgc atgagacgct
    17041 cggtgaagtc ttcaggtgca tctgcagacg cagccaagtc gccaataaac ggggcaagac
    17101 gtaatcgggg taaagtctca aggacaaggt tatcagggag aaaagggacc cggtcaagct
    17161 gtcgggcgag atggcttatt gatccggcca cgtcagcgca aggttgcagt gccaagagca
    17221 tggcatacgc acctgtccag aacatacagc ccacataatg tcctccggcg catctccttt
    17281 tctaatactt gagaactatc ttcccccggc actggagcca ctgtgtgaat ccccgccttc
    17341 tgcgccgcac tacaagcaga ggcgatgcct tcccaaaatt tatcagtcct cccttcacaa
    17401 gaggatctga aagcggcaaa taaaatgtgc tggacccgga ccagagaccc tttccagttt
    17461 agagacagac aggctctggc aagctcacca ccgaggtgac tgcaggtgtc acgaatgtcc
    17521 gagagtgact gcccccggat ccgatcaaga gtgtgcgtcg gagaaggcag gaattgcgcc
    17581 gagtaggcac caatccgaag taccagagcg gcaaactcaa tgtcatccac agggaggggc
    17641 cactccttag tccaccaatg ctgatactgt gtcagaaagc tgggtgggtg gatgatctgt
    17701 ttcatcctgt tccatggggc atcagtcgac catgaatcta atatgatcac taacaaggga
    17761 cctaccagtt caattcatcg acaaaatact gcatcaggaa atctaggatg ggacggggag
    17821 ggattttttc caggacttgt ttgactgtct ctagcaccgc agttgacagg ccctgggtgc
    17881 tttgatctgt gtccccttca ctgtccagat cccactatgc cgtttgagat tagccatatg
    17941 tcaagagggt ggatccacag ttgcatgtgt gcttctcact tttttgagca gagccatggt
    18001 attggagtca ctgtgctcga agtagccaaa ggatttagcc agagctgagt gtgaattaga
    18061 cgcgctattc tgtgcctcgg caggcgaggc cttggaagat ccatttggta actggacatt
    18121 gggtggttcc tggggctcag ggtctctcgc tggctccaag aggaaagtgt tggaggggtc
    18181 tccagtaatg atggactggt agacacattc ctccggccgt cgacgtcggg tgcaatggtt
    18241 gcacgggtac tggcggttgc actaattttt tttttagttc gcattaggac tcaagctttc
    18301 agctgcccag tgtaggatta gcgatgttta cgcactctct gtttcctagt gtagcagggc
    18361 acacaggtgg tgacccgacg ctttcggccg gtgggatgca ttgcggctcc tcccatctgg
    18421 tcgacaactc acacaacacc agcgggcccg atgcccttgt tatgtctagc tgtcgcacaa
    18481 gattaagcta ttcttcttcc agataattat accttagtgg agggatgagg gggaatatct
    18541 caatgtggga ctgtttctgt gcctggaggt cgcttcgggg tagtgggggg cgtgtctcca
    18601 ccagcatttg ggagggacaa gccagacaga cacagaagac cagataggca gactgtcaga
    18661 ccgtcagaca tttggggtca gacggccaga cggtccgtga gcctgcatgg atttaacttc
    18721 agtccggata agatcggcca cgcggaacgg aagaacccgc cggatctact tggttatgct
    18781 tactcggttt actcggcttc aaactctcat caacaggaaa cgtgcggctc tctggctgtt
    18841 tctgatggtg ttattggtgg cctaaatccc gtgcatccca attacactga aactaaccct
    18901 cctgatttgt tcccatggca cccgggccat cccggagctg tgcctaatat gcttgatcta
    18961 tcacgtcctg tgaagtacgt tcaacgtaga ctagactcca gcagaacctg taagatcaga
    19021 caagctgcat ctgcaacctt caatgaattc gttgaccagc aggatcgcca cgcttatctc
    19081 aacaacaccc acttggagcc gctcattgta ctgcatatca catttttgta ctacgtaccg
    19141 tcagtggtcc gtgcgagtgg gttggagcat ggggaggatt tgatcttcgt cagagggccg
    19201 ttaaccccat aattatcaac agtctggttt catcccatct cggcaccttt taccttccca
    19261 atatggcatg cttctcagtc cggcttgctt gggatcccct caatctgggg gaaaggaagg
    19321 tggggaagga tgaagggggc caaaaaggac ctctgaggaa gaggtctagt cttaggcgcc
    19381 cgggactgtg gctgaaggta ggcaatcctt ccatttattg ccaatgacag aagccagcaa
    19441 acttcggctc gcaacagaga aggaatcgaa tccatgcgaa gtgtctcgct tctgagtagt
    19501 gctgacgaaa gtcacggccc cgacatccat cggtcgcatc gggcgatttc gcccgtccct
    19561 cctccgtcca gcttatcacg atcagcatca acacgagccg ccaagaaaag gaatctgagg
    19621 acttgtctgt tcctccaacg tcttcggccg aggtccgtag acagcacacg gcgtcttcat
    19681 caactggaat acccgaatgt gaaggctgcc acgaaacggc cgacgcgggg cttaatgagt
    19741 gcagtagctt catgcacgta tggtgaacat ggcagcagat acaccatcag aaagaagaca
    19801 actacagcta ttcaccgtag atagtgcagg agtcaggatt caagaacagg atgaattgct
    19861 atatagggcc tgtgttgcca tggacgagac agttcatttg gcaaatacag caacttctct
    19921 attgaattcg acaaaaagca cgaacgatct ctatacttca tctttaccac tctcataccc
    19981 atattcctta ctgagccatc atgacacccc caagatcaaa tgagtgcgag ccaattgcca
    20041 ttgttggcat gggtgagttg attatatcgg gctttggaga gaaatcaagc attgttaaca
    20101 tgaataggct gtcgcctacc gggaggtgtt caggacattc ctgcgttgtg ggagttcctc
    20161 cgggaccaga aggatgctca cggggagttt gccgcgccgc gtttttcagc cgaaggcttc
    20221 tatcatgcca attcagaccg gcctgggact gctgtagcca gcagtggctt cctcttgaaa
    20281 gaggacccgc ggctttttga cccgtctttc ttcggaatta ccgatgtcga agcggaaacc
    20341 atggacgcct cgcaacgcaa gctactcgaa gtgacgtatg aagcatttga gaatgcaggg
    20401 gagacatggg acagtgtgtc cggtagccga atcggcgttt tcgtcggcga tatctcgttc
    20461 gacaattatg tgtcccagac gcgtgattgg gactatagcg gcaaatactc ggctactgga
    20521 gcctttccca acatgctggc caaccgcatc cactacgttt tcaacctcaa aggtccgagt
    20581 ctgctaatca acagtgcatg cacctcggcc atgtatgcgc tccacctggc tattacctct
    20641 atgcgcaatg gggattgcga ttcggccatc gtagccggat ccaactgggt tatggacccc
    20701 aactgccaca ttgctatggg caagctggga gccctgtcac cttcttccag aagccacact
    20761 ttcgatgcct ccgcagacgg gtacgcccgc ggcgaaggtt tcgcagcact ctatctaaag
    20821 acagtctcgc ttgcaaccca agatgcgtct ccgattcgcg ccctaatcag aggcagtgcg
    20881 gtcaacgcca acgggcgtac gagtggtatc accaacccga gtggccccgc acaagagact
    20941 gtcattcgag aagcgtgagc tctatccatg ttacacactt tgcacctcac gcatgacctt
    21001 ctaatactga cttgaacagc tacaagaacg caggggatct cgatccctcc gaaacaaccc
    21061 ttctcgagtg ccacggaaca ggcacccgcg ttggggaccc aattgaggtg acggcagctg
    21121 ggaatgtgtt tgggccatca cggtctactg tccatgaaga tcgcctggtt gtcggatctg
    21181 ttaaaactaa cgtgggccat ctggaaggtg cgtgcgcctt gccaggtatc cttaaggtgg
    21241 tcgcttctct cgaggccgga gagatccccg cgacgctcgg tttccagacc cccaatccac
    21301 gcatcgactt tgaccaggcc aaggctcgcg tcgtcaataa gacagagccc tggcctaaag
    21361 accgacttaa gcgtgccagt gttacttcgg caggctttgg agggaccaac ggacattgca
    21421 tcatcgacca cgtccacaat gtcatcccgg agtatgtgaa gcctggcgtc atttacgagc
    21481 aagttgagca gtccaatggt acaaacgggc atgctgttaa tggtaccaat ggcactaatg
    21541 gcacccacgg caccaagcca gaagcactct cccagctgca ccgtcctata ctccattctc
    21601 cgaccctcgt tagacgggcc gatgccacca ctcgccagat ggtggttctc cccttctccg
    21661 cgcacaacca gtcttctctg attgcgaaca tggaggcgct gcaacgatcc attcctcatc
    21721 actcattagc cgacgtggcc tacactctcg cagctaaacg ctctcgattc tcgcaacgag
    21781 ccttctcgat tgttgacaag gaccaggtca cccaggtcgg atcggtcacc gacaacggac
    21841 caaaggtgtt cgcctcgcct caacgggtaa acgtcggttt tgtcttcacg ggtcagggtg
    21901 ctcaatggcc agccatgggg gcggagctgt ttgagtacgc tgtgttccga gatacaatcg
    21961 catacctcga caccgtgctg gctgtgttgc cccagcccgc tccatggaag cttgtagaca
    22021 ttctgtgtgg gaactgtgac aaggatctca tccagaagcc tgccgtgtct caaactgtat
    22081 gcaccgcgct acagatgggt cttgttgacc tgctagcatc atggtctgtc cgcccggctg
    22141 gcgtcgtggg tcattcatcg ggcgaaatgg ccgcagcgta tgccgccggt cggatcacag
    22201 ccgcagaggc catcaccatt gcttactacc gtggatacat ggtctcattc aaccagaaaa
    22261 agggtgctat gttggctgtc gggcttggag cagaccaggg tgccgagtat gtccggcagg
    22321 ccggtatgga gggaagagtc aaggtcgcgg cgatcaactc tccggcgagc atcaccatgt
    22381 ctggtgacgc tgatgccatt gagcagctga gcgtccagct cacccaagaa gctatcttta
    22441 accgacagct tcgcaccgga ggacttgcct accattcaca ccacatgctg tcatttggtc
    22501 acgattacgc tcaggcagtt gatgatgggt tacagcgtct tgccagccta ggaatcaatg
    22561 acaccacttc caggtactcc aacattcctt gggcttcttc agtggtgcca caaaaaagct
    22621 caaccatgcc tcgcgaggaa gtgactgctt catactggaa agcaaatctg gagtcacccg
    22681 tacggtttac cgatgccgta tccaagctcc tcgacatgga tgacctgaga atcggcgcaa
    22741 cggtggagat cggcccacac ccagcgctga aaggcccatt ggggcagata gtcaaaggtc
    22801 tgggacgtac gattccccac gttgcctcgg tagagagagg ccaggatgct cgccgctcgc
    22861 tacttggact cgccggaacg ctatttgccc tgaatgccga cgtcgatttg gtggcagtca
    22921 acgccgtcga tgagtcgcat ggtgcgggaa aaagaacgct catacatgga tgcatggcta
    22981 ttgacctgcc gccctaccgg tacacctatg ggcctatcaa gtaccacgag agccgtctaa
    23041 gcaaggagta ccgactccgg cgctggcccc ggcatgatct gcttggagcc cgtgtgccag
    23101 ggacaactcg actgcgtccg caatggcgaa acatactccg cttgaaggat ctgccatggc
    23161 ttaatgacca tcgcgtgcct cctcacgttc tgcatcccgg agcggcgcat attgtgatgg
    23221 ccatgctcgc agcagagcaa gcctatgcgg aattccccga tgcgttacct gttgctggct
    23281 tgactctccg gaacgtctcg atcaagaaga ccctggttgt cccgcaagat gacaagggga
    23341 ttgagatcgt gctcagcatg gagctcgagg atggtgccac cgccgcatct cctggatggg
    23401 caagcttttc catcgcttcg gtcgttaacg actccgagca gtggacggaa cactgctcag
    23461 gtctagtcaa ggttgatgtc gttgccttta acgcgcctgc ggccattgat acaactacca
    23521 tggatggacg cgctgtagat gcgcaggcct ggtacactcg ctttgccgac atgggactcc
    23581 agtttgggcc ctcgttccaa gggtattccg atatctgggc tgacccgttc agcaacgtgg
    23641 cattggccaa gctatcgcta aacaccactg caggattgtt ccctggaggc gagtccaggt
    23701 atcccatcca ccccgcctcc ttggatcttg ttatccgcct gggactcatg gcatgtaatg
    23761 gcggccaggc agaaacggcc agtgtccagc tgcctatcca tttcgatcag atgcggttca
    23821 aacttggctg cctccaaggc cgtgactgga tcacaggggt atcgcgcggc gagctacgtg
    23881 ggttgcgtgg agcgtacgcc caactgcaac tgttggatga ctccggcgag gctatcttgg
    23941 acgtggacaa catgcgcttc accagcctga acaatgagca gcagtcctcc gcacaggatt
    24001 tttctggcca agcttattcc agtcctttcg cgcgtcttgt ctggaggcct gatagtcgca
    24061 cattgagtcg ggatcagtgg aacaaacttc ttgcgtctgt ggacgggacc acgactttct
    24121 ctcggctctc ctacctcttc gacctcgtag gccatgccaa cccagatctt cgaatcctgc
    24181 agcttagcgc tggcagcgat gaccggaatg ctggtcaagc agtgctaaag tcccttgtcg
    24241 gccacaatgg catcaagcgc taccgggaat acgtcgcaac ggacacctct gccgagcgac
    24301 tggactcctt ccgtgagact gtctcagctt tccgcgacgt cagatactcc gtgctggata
    24361 tcagccaaga tccctcggaa caggaattcc aaatagggac ctacgacatg atcctctgga
    24421 gcaatgtgga acatggcccg gctactgagc aggccctggc aaacgccaag aagctcctcc
    24481 atcccggggg ccaccttgta ctagtggacc gcatgaatag cagcgaactg gcatgggacc
    24541 aatgccttcg gcgagttgga ttcgactcag gatataagct agtctgtcgc gaagctgatc
    24601 tgcactccac catcatccta tccaccctgc ccgatccggt accaactacc aagagcggca
    24661 accctgtggt ccaccttcta cacgggtctc aaggcacttc agcgcttctc catcatctcg
    24721 cccgggctat ggaacagcac ggcctatcta tccggatcag tcctatggac caagcaataa
    24781 acgtactcgc tcccaattct cgcgtggtgg ctttccttga cggagaaaac cttctgtttg
    24841 ccgccgatca acgccgactg ggactattcc aacatctagc tgcaaacacg gcgagcatgg
    24901 tttgggttac ctcgtgcggc ctagtgaagg gccgaaatcc cgacggcgca tttgttagcg
    24961 ggcttctacg taccttggga actgagaatc tcgcagggca gttcttgtca gtcgacgttg
    25021 atgcggaaga ctttcaggtt cctggcctgg agatggacga gctggtccgc tgcttggtcg
    25081 aacaggagct cctcctgcag cccaccctcg atgataaagg acctcccgag gtgaatcggg
    25141 acctggtttg gcaagacggc tgcatgtgga cgagccggat cgtgcctgat gggcagctgc
    25201 agggatacgc ggaggtggct cccaccaggc aggaagttga cgtgtcctca cggccactga
    25261 gcagccttgg acccgtacga gcggcctttg agacacctgg tattctcacc tccctctatt
    25321 tccgtccgta tacagagctg ttgcaacccc tgcctcggga ttatatcgac gtcaaggtgg
    25381 atgctgtcgg gctcaactgg aaagacctgg ggctgtgttc cggtcgattt gatgcgaaca
    25441 acctctccaa cgaatactgc ggtgttgtta cccaggtagg agctgatgtt actagattat
    25501 ctattggcga ccgggtttat ggaatgggca agggacactt tggcacgcac actcgtgtgc
    25561 ccgcaggtct ggcacagaag ctggccgcgg acgtcaacgc catcgaggcg gctactatgc
    25621 cgctggtgta tatgactgca gtttatgcct tcgagcatgt tactcgcctc aagcctggcc
    25681 acaaggtact gatccaatcg gctacaggcg gccttggtct ggcagccatc cagctggcgc
    25741 ggtccaaggg gccaccatct acgcgacggc aggcactgca gacaaagtcc gtttcctgac
    25801 agaccacatg ggtgttccag catcgcagat cttctcgtcc cgcgacttgg ccagtctgaa
    25861 ccgcgccact cagcaacatg gagggtttga tgtcatcctt agcaccgccc agggcgatat
    25921 gttgtacgag tccgtcaaag ccctcgcccc cttgggtcat ttagtcgacg tgggtcgcct
    25981 ggatgtcact agttcccaaa ccatgggcct ggaacttttc caaaagagtg ctgggtttac
    26041 ctcctttgac cttggcctcg ttgtggaacg cgactctgtc ctcggggcgg agctgatgca
    26101 gtccgtcgac gcgcacttcc gcgctggcca catcggaccc attaagccct attccgttgc
    26161 ggacattggc cacctggacc aaactctctt gcagttctcg caaggcaccc atattggaaa
    26221 gcgtgtcatt acctaccaag acccgtccac cttgctgcgc actctcccca cctcatccgc
    26281 aaccccggcg cgcttcgacc cagccgcccg ctacatcctc gtcggcgggc tgaccggcct
    26341 cggccgctcc atcgtgcggt ggatgagcag ccgtggtgct cgcgacatgg aggtttggtc
    26401 ccgccggggg caagcaacct tgcccccgaa gcacagcgta tgatcactga gctggcagcc
    26461 caaggcatcc gagtccagcc cgttgcctgc gacgtaacca accgtgacgc cgtgctccac
    26521 accatgcgat ctgcgcatgt tgatcccaca cgacctgttc gtggtgtctt ccactttgcc
    26581 gtatcctacc aggatatctc ctttgacaag atgaccgaag cccaattcaa ccaaggcatg
    26641 gcggccaagg tcttcggcgt caagcacctc cacgatgcca cggcctccat ccctctcgac
    26701 ttcttcgcta tgacctcctc cttgggaact gtctatgcct tccctaccca gagcacctat
    26761 ctcgctgcca acaactacct tgattacttt gcccgctacc gccgccggct cggtctccct
    26821 gccacgaccg tcgccctagg cttcatcaac gacctgggcc cgctaaccaa tgaccccgtc
    26881 accgtcaacc tcttcgtccg cgccaaaggc caaaccatga cgggagctca ggtcgtgcgc
    26941 atgctcgagc cagcctttgt gaatgagcaa cccaatgccc tctggctcgg ccataccgat
    27001 gaccccctct ccgcatccca catagtcact ggcatcgacc cagccgtcct cgccaagatg
    27061 gcccggtcat cagctgcctc cctcgcctct tctaccattc ccagatggta ccacgactct
    27121 cgtgtctcct taatgttgcg tgccctagaa gacgcctcgt ccgctacctc ttctctcagt
    27181 agctcggaca tccatgcctc agacgcatca cctactgccc aactgagacg acaattcgac
    27241 cactccgttg cgacgctccg tgcgggaggt aaagattcca aggaggatgc atggacggag
    27301 accatcaaat tcgtgactga ggccatccag gccaccgtgg caggcatgtt gtttgtggat
    27361 gtgggaagcg tgaatcccaa caagacggtg gcggagcatg gcattgatag tttgctggcg
    27421 gcggagtttc gcaattggtt ccagggggcg tttgggaggg gggtgagtat gttggagttg
    27481 atggatgcga ggatgagtct agcgttgttg gcgaggtcgg tagttgaggg gcggtgggtg
    27541 tgtgatattt acccacattg agtactactc ttcttagtac tctatagact gatatcataa
    27601 aggaagtagt ttatttacac cctcatcttg ctaatgtcca ttacatatta tcccaacaag
    27661 tatacagacg acattcatct actaacaacc tccataccta cccccaaacc ctctgataat
    27721 ctaccacccc caacatgatc cactgcccac tgaatatacc cccgatacct gccatccaaa
    27781 tgccactgaa tcccctcgag aatatgccgc ggccacccac aaataaacca aacatgatcc
    27841 agccgatcaa gcggatacaa aaagaacgca aacagaatca acgccaccgg ctccctccgc
    27901 tgcaaatcac ccaccactgc gtccggcaac tgatacaacc acgcaaagac aagcgggaag
    27961 agagccattc ccattgtacc ctgcggatcg ggacccatga tggcgtcgag gctgtggcct
    28021 agtcggtcta gtgtttgcag atagattgag agccgtgggt cgtcgatggg gatggttgtg
    28081 gtaaggaggg cgcggtaagt ttctaggtgg tgcgggtaat cttctaactt ggttttgttt
    28141 tgtgatgcga tatgggagtt ttcatgttcg gtttgaggtg tggtgcgaga agaagaatca
    28201 tcgccctctc catggatgga gaaaacgctc gttggcatat ctccgctaca tagctcgaat
    28261 acagaccgca caccgaggaa caaagacaag tggcctgggg tgccatcgct ccggaacgcg
    28321 aggtactccc ccggttgagg gccacgggcg agacttgaga tgaagatgaa tattgcggag
    28381 gcatacatcg cgggactgtt gtcgcggtca aggtgcggta aggtggctga gacatctcga
    28441 atagcaacgt taaagtggcg ttcggcttca gtgtatattt ctgcttctgt gaaacccatg
    28501 gattgggacc attgctgatc gtctgatcgt cgcacgaggt ggaagccgga gaaggcgagg
    28561 aggatgtgca tgacgtagtg gtgggaaaaa gcgatttgag ataattgctg acgggctttt
    28621 ggttgggcgc cggttagttc aggggaagtg gagaagtggt gaaagaggag catgtccagg
    28681 gctgtgtatt ggaaggggcg cttggctagg tcgttgtttg atgggggtga tggttgggtt
    28741 gtgtctggtc ctgatgtgag aggtgtgcca tggcctcgtt ttgggggttg aaagttgacg
    28801 gatgaggatg tgtagaaggt gtagctatct gtgctggggc cctgtgaggg tggtgatacc
    28861 gagtctgatt gctgtgattg tggagaggag ctggagttag tttggggctt aaagctgtag
    28921 tcgcactcta ttgaatggcg gaggcagttg gtgcagtgtg gcttgatctc atcgcactgg
    28981 ggatcggtta gtatctctca ctcattgaag cgcccagagt ggagaaggcg tcgggaactg
    29041 actttaattc tacgcctctt acagttctta catcccagac gagacttgcg atggcttttc
    29101 cgcgataacg tttgagtgta tggagtgaga gaagcgccca ttatctcaca gtacaggtgc
    29161 tttgattaag gtgaatgagg tggaggtttg gtcactggca cgcctggaag gctagataac
    29221 tagttgagga atgcggcgta gacaccagtg gcatgcttga attttaaaca gagcgaataa
    29281 cgttggttcc agaagggctt cagggggcgt tgccccactt cactgccttt gcagcctgcc
    29341 cggggaaatc ccggttctac ttcggtggat tttccggcaa catctggtcc agtaattgta
    29401 ggttctgttt cctcttgcga catgcatatc tccatttcat gcctggtatc tgcatagcca
    29461 ttgttttctc gcttcatgac ctgtacattt gtatagtgaa caaagcggtc tctgtgatgg
    29521 ataccgactg cgggctttat attcccatct cctctcgacg ccttttaacc tccattttca
    29581 gactcgggtc aactgccata ctaaacccac catagcgaat ctttggtacc gtcccttcca
    29641 atagcttcca gtcgtaccgc agtaggagat agatcaaggc aatcttaacc tcattggcgg
    29701 cgaagaagcg tcccggacaa gcatgtttgc catgtccaaa agccaaattt tccggagccg
    29761 ttgtgaccag ctgcgccttg gtctgtcgct cagggtcttc gcgcatcttg tagaaccggt
    29821 acccgtccca ggcagctgca ttttcgtagg tgtcatcatc ccagagcttg tgggccgata
    29881 ccgcaagcat gccattcttg gggatgaccg tcccgtcgga gagcttcact tccttgagag
    29941 ctacccggcg cattgaggct gttgacaatt tattcagcca aaccagtgga aggtatcaaa
    30001 acagatgggt ttatgctctg ctcaccgttg ttgattggtt tcagcctttg gctctcccgg
    30061 ataacactat ccagcagttt catgttatac agagcggtct ttttccaacc atgctgttgg
    30121 agagtgtcaa caatttcctt gcgtaaaggc tccaaaatct ccggattttg cacgagatgg
    30181 gtcattgtct gagatgtcag gtcggaagtt gtgtggatgg ccgccacgga aaggattagc
    30241 tgcgcactaa cagggtcata gggacgacct ttggcggcct tctcaaacca ttcgatagca
    30301 tcatcgaacc cttgtgattg tttacccttt gcatgaaggt gtttcttaaa ttgacgcctc
    30361 tcctctagta ttggtcccat gactttccta gctactttca cctgggccct aagcttacgg
    30421 catcggggca agaaccagtg tacgatgggt cgaatagctg caggccacat gcgaagctct
    30481 tccgccgcta agaatccatc agtagtatag tcttgagtga ctcgcagcca ttcttcattc
    30541 cggcacaact tttccccaag gaagacacgg gaggaaatgc gggaaataag agccaccatc
    30601 acagttctca actggatcgt gtgccattct aatcatgaca cacattagca ttcctatcgt
    30661 cgaattggaa agtatgagat tgtctacctt cattatctgt caacagttca cggacggcga
    30721 cagatgtctc gttggcaagg ggctcggtga ccttgtctgc caagatgccg aattgtgagt
    30781 tagtatacag tcatgccacc agtgccgtga agtccgataa ctaactcagg tattttgtca
    30841 agtcgtttcc gataacagcc tggacaatcc ccgagtcttg actaccttcg cggaatccgt
    30901 caaatccagg tagattgcca tgaaatgcct ggcatcttgt cagctacttt cacacgagct
    30961 ccggatcaaa cataaaacac atgaaagtcg gaacacactt cgaatgtcca tcgagagaag
    31021 ctcaggcggt cgtcattcct gatctcattc gccatactcg gagggagaat tgtcactttc
    31081 ccagtgtcgg tatgcaagag cactggcgta tttgaatgag ttgtaaacca atcccatagc
    31141 agtcttcgcg cattggagaa gtattcttgc tttactctag tagacgtgag ctcgaagggc
    31201 ttctttggat tcagggccgg gtccttgtat ctgaagcttt gaagtaggag aaacgcgagg
    31261 cctaaagcca gcgatacaag gacgggtact ggcatcgagg tataacccag catgttctcc
    31321 atgcttgcac gcaagggcct aaaaggggtg tctgtaaaga acataacgta gtagtgctaa
    31381 caaaaaagat gagatagggt agcggcatca attccaacaa cggatgagga tagacgccta
    31441 tcgatactta cttaaatact tccaaattgt gaggggcttt aggcgttgag atggccagga
    31501 tgtagttgaa acaatgcctc gttagtatgc cgcatttccc gcttgatctg caagaagcgc
    31561 cgtcagggtg gaaccccact gattcagcgg ttatgcattg catacgggca tagcaggaag
    31621 tgtctcgtca tccattagga tcattcatca tttaccatga ataagagagt ttgtgcactg
    31681 gcattgaacg cattgatgcg ccagtatgtt tgatctgtcg gtctcgactc caatgcagga
    31741 cattatttat ccgagacata atactcgtag tagacgatgc atcgaataat cgatatgcct
    31801 ctgaagtggt aagcacagga tgaaagcaac tgctaagttt aggtgaaatt tccatcccta
    31861 agatagtgtt gttcacaagg aacaagactc gcaatatgaa ccacaaccac acataattga
    31921 acagaagctg ttactcctgt ggatagctgc attgagttac tctacctgag ttgcggggaa
    31981 tgtcaaatca gccctaactg attggccgcg tgtttttggt tccttgtcca gcccacgcag
    32041 agtcgtcatc actatccact tccaatcgaa aacgactgag cccaaccaca agagaatatc
    32101 agtatgcttc ggttcaaatc gtcccttctg cataagatat acgcgtagac gtttgaacta
    32161 gtctaaatct ggtataggct tcatgcatga attgtcccca cgtaaacttc ctatcccgag
    32221 gacataagca atgattcagc gcttccgaga cgcctgcagt cggtgcatca gcccactcat
    32281 tgctgggaag ccaccttgtc tgttaaccgc atgactggct tggtataaat cctttgactt
    32341 tcatttgaag gtatcaggtt gacgtcaagg atcatttaac ctagtgcccg gttttggatt
    32401 tgacaccttt cagatccaag caaacttgac atttgggtaa gtttcattgg ccaaagaaca
    32461 gcccattcca tctcagtcca tctgactttg ttagccagat gatatgtaac atcatgcttg
    32521 gcgatgaaag agtcatacgg gtgttttggt cgaaaagctc gtctccaccg tcatccaccg
    32581 aagtttggac aaaatgattc acgtcgttct atattgccga gctaacacat ttgtcccagt
    32641 tcttggtgtc tattttgtct tagcgcacct taagtgggtt ttctattgtt tctgataccc
    32701 cagtcctatc gggataccat agggacccca aagtacatac aagatctact aagtatacag
    32761 tacattagag caggcggtat ttactgcgaa ggattgaaac ggagtatcct agtttcagtt
    32821 tagagaccgt gcactcagcg acacaataga acatggtttt ctatgtgcaa gtgttagttg
    32881 tttctggaca caccctcctc gtttacttgc aatcatctac aaatcatgtc ccgagtggag
    32941 agcacaataa atccatatca ttctataaac atcaatggga ctcgtctctc tatcaaccac
    33001 tccgcctcaa ctatccatcc atgccactgt tcttctattc gtactatatt cttacccccg
    33061 ccccctttcc ccaacactaa tccctgcaca attctactcc cgcttcgtct ctcctgcagc
    33121 aggcccaagc aacctcgcaa cagtcggcag cggccacgcg agctgtgcaa ccgagtcccg
    33181 ttgcacttcc ccggaagtaa tcaaatcaat gaccgccacg gcgatatatc caccaatggc
    33241 agtgaagaca tgccaccttg tatgacttgt tagccaagtt caagtttatc ccggaccatg
    33301 gggaaagatc tacataccag ccatgcagct caagcaagaa cgccacgggt agcccgaccg
    33361 cgtgtctggc tacgatcaag gattgacaca caaactcgtc aatcagccag acgagatatc
    33421 cgaagatgaa gcttgctgca tacatgttag aattaactac attctcatct cattcaccta
    33481 gtaggtaagc caataataag agtgtagata acataccaca tccaaacagc gccacggact
    33541 gaatcctttt acgggcctca acgtccggga tctcgcgagg aatgatcttg agcgtgcgag
    33601 tcgtgatcag acacactgcg gccccgaatg tcacggcgtg aagcaggaac tcatccatga
    33661 ccatgtggac gaccatgacg atcgtgaaca gtacagagag aatgattcct actgtctttg
    33721 tgtactgagg ggtggcctgg aaagatagaa tgcggtagag gagtggtgta gtcaagaggt
    33781 gcatggaaag ttcatccgct gttgagacgg atcagctcag atcacgataa ttatcattcc
    33841 gagtaagctg aagaatagag ggaggcagta cacatctggg tgtgatattt cagagtcata
    33901 tggtaaccgg cagagcaaac accgacgcca atcaatccgc agtatgtgat tgagcgtggc
    33961 ccggtttggc gtctgctgtg gagctgccag agaccgtaga tgccatatag aactagagaa
    34021 gagtgttaat ttgtggacta ctgtaagggg ggaataaacg cactatagac aaagctgcta
    34081 agagtattaa taaactccgc aacatatcgc gtaattacat agtcctagag gacaaatcag
    34141 cgattattgt tgtgggccaa gaaaagacca gattgcgctt gctgtagacg gacctcttca
    34201 cagaagctgt cgacattggt tagtctccga cgtatacttc aattggctat taattaattg
    34261 acatacttca aataagaggt cggggcaccc cagaaaggcg aaatcgcgga agccattgtc
    34321 gcgagcgttc ctggcgatca atatggggga gttgggaatg agaaagaatg gggagattgg
    34381 cagacgggct ggaataataa taaatcggct ccttcgggaa ctccaccgcg acggtgaccc
    34441 actcgtgtct cccgtgctta gcaggccttg ttcctgcacg gtttccgggg ttgaagacaa
    34501 ttacagtttt gcatacggga tgatgtagcc aattttgaac ctatatcccc acttgatccc
    34561 gtcaaccaag tgcctaagag ggtgaagtca ttacaggcac ctggaataca ttttggaccg
    34621 cctgatgggc ttacccgacc gttccggacg gggctggctc ggcttctatc cccagtcttg
    34681 gcattggcgt tgaacaaggt atgaatctcc tggactattt caaagttgct caaaaacgat
    34741 gttttgcttg tataaactaa gccaatttag tctcaaaggc gatactcgct ctcttcaaag
    34801 ttcaattctg cgatgcaggt attagcccct agcatatccg acttgccctg tggatataat
    34861 agtttgctgc ctgaggcctc gcaatctaca caaacaacgc gtcaacacct ccttcttgcg
    34921 aatggttcaa cagaattcga ggctcctcaa cggctagtcc gcgtttgaaa ggttcctacg
    34981 tttataatat tgcgtctctc aagaaaagac cccgattccc catcatttcg catatttata
    35041 agtagccaca aaacttagat gtaggatatg atggtcacat aacactcacc catgcagctg
    35101 aatgtcgtca catgtgtaac aactatttcc ctcaatattt ccacactcca cagatttaaa
    35161 cccactcata ccacggcaaa ccatctcgaa gaacctcata atctgtccct gagtcaaatt
    35221 gcgggccctc cgcatctagg aaatatccac gcgcacactc gttaaactgg acccgcgtcg
    35281 tctgctccac ctcatagaaa tgatcgtagt gcacatccaa cgcgtctttc aacgtcataa
    35341 cctccccacg cggatgcaag gcgtcccatg gcttgacgca tacttgggcc ttgcaggact
    35401 tgagcacgag aagaagggag tcgagtcgct gaacgacttt ggaaagatca acgtttaaga
    35461 tggtgtgaga ggtcgcactg ggttgttcaa ttgcggaaag gagattatga agttgatgag
    35521 ggtcagtctg tctctttggt cagatttccc aagagaaatg ggtttgggag gggccaatac
    35581 agtcatatca tagagttcat gctcattgtt acaccaaacg gaatagtaaa gattatatcc
    35641 aattcccttg atgcggaggg ctttgtatgt gttgttgtat gccgataggt caactttcat
    35701 tatcaagatt agctcagcca tggtcaaaga gtggggtgta ggagtagagt acgcacagtc
    35761 gtatataccc tcgcccgccg catatcccca atattcaacc gtgacatgtt cctgtctctc
    35821 ttcttgggcc ctctcgatct ggctcctcgt caacgaaata gggttgccat cgaagtcctc
    35881 tcgaagggga atacccagca gctcgagaaa agtgggagca agatccgtat gcgtggtgac
    35941 aatatccgta gatacattct gcgcgatatc gggaccacga ataatcaaag gaacattgat
    36001 gtcttcctcg tatccacacg acttgcctgg ctgaagtcgg tgttgaccaa tgtggtatcc
    36061 attgtcacta ctatagacta tatatgtatt gtcaaggata ttgtattcct tcaaacgtgt
    36121 aaataagcca tcaaccagct cgtcaacggc ctggagggtg cgtagacgct ggcggtaaaa
    36181 atgatcgttg tagtcaacat tagtatcgtt ttgtcgcttg agagtcttaa tccagttggc
    36241 gcctgaaggg atttccggat tgaaggaggg ggtgcgggga actttgacat ctgggaatag
    36301 gtgctcgtgt cgcttcgcgg ggataggtgc gctgaagctg aatttagggt tggcgtctaa
    36361 gccagttcca ttcatgaaaa cgttgcaatg cggtgcaatt ggagcaaccg tgagaaagaa
    36421 gggcttttgg gccgtgactg cttcgttgag gaggcgatat gccttttgtg cgaggacatc
    36481 agtgctgtat tcgccttcgt agctttgggg tatttcgtgg tctcgttgga aggtactgtt
    36541 aaggtagtcg tatgtgaatg gatcgaggag gaagtcctac atgacagatt agagtgccga
    36601 ctgaatagaa agtctgctgg atgactcacg ttgccggtga acccagctgg gaaggggcgt
    36661 tgtagttgtc gaccgtgtgg acgttgaaca gtttaccagt gtagtaagtg ttgtaccccg
    36721 cttcctgcag ccaaacaggg aaataattgt catttagacc ttgagagata aattttggat
    36781 agccgcctga aagcgtatga gaatattccc cgatataagt ggcgatgtgc agtacactca
    36841 ccatgcggag gattgacatc cgtgacgttc gtattgtggg ccagctttcc cgtccaaagg
    36901 gtcacacgcg atggacaaca gacactggtt gtacagtagt gactgcgata gtgtgttcct
    36961 ttgtctagga ggtgctttcg tacataaggc atgtaatcca aagaggcgag atgggcgtct
    37021 tgatcatcgg ttaatatgaa gacgacgttg ggcttggcgg tcgcagaaag cggctgctgc
    37081 tgctgctgct tctgctgccc taccgatttt gtagtaagcc cagccagggc taacaaatag
    37141 accaggtgtc gcatattgct ggtatagtat gagtttgtgg gcttcgatgt caaagcagat
    37201 gaacggcaga tgcagtgagg ttcaaggtaa ttgcttaata accccgcgca taacgcaatc
    37261 cgggtcaaag cggaccaagc acaactagtt accttgcagg atgcccagag cataaaagtg
    37321 tgatatagag atgcttaata tcttaatatt ctttcaaggc attgttatta tctgaccgcg
    37381 tgctgaagca cgatcgtcat acctcatgtc aatgaaaact ttcgtcgaca cttcatttaa
    37441 gcatttcgga tactgcttga cttagtactt agtacttagt actagcaagt cgtggcggat
    37501 gtatcgaggt tgagaaaaat atatcatgat ggatgatctg gcaaaataaa tggcagccct
    37561 gcactgcgga ctattgcccg cgacaactgc acaattccta acgtgtcaga aaaatggaac
    37621 aacaggaatg gaatcattgt tatggctcga ttgaaagaga taatgattag aatacaaaag
    37681 tagcgagtac attactgcgg aatgagtact tacaagtact actatgtggg cgtcaccgca
    37741 gcgaccattt tctgccgcgc tctgaagggc ggacaggatt agctttgtct gccacggctc
    37801 catttgcgga cgatgggcca ctgcggggcg tcttcagatt cattcaagcg gccagtttca
    37861 acaactgggt cccatagctc agttggttag agcgtgacgc taataacgtc aaagtcgagg
    37921 gttcgagccc ctctgggacc atctcttttt tgcttttgac tattcttcac atctttttgc
    37981 tccagcaagc ttttgccgct ggcaaatcaa atgacatgct cgttggttgg cattggttgg
    38041 tgctgactaa aagccaaata ctccctttgt cagtgtcaat tttttttgtt tactatcaca
    38101 gtaaaacacc tatacaagca accactgata tagggcatcc tccacttaaa gtaacgttaa
    38161 aatatgtgcg gctagcctgg aggagcaagc tggaaagggc cacttaagga gccgtcttca
    38221 ttgtgatgtt tcctttggtt ttagcaagcc cgagtacagg ttttgttcat gacgcaaaac
    38281 tagcgagagc ctggcaatct taatctggta ctgcgcgtat gtttgttggc gcaagctttc
    38341 aaggaagtct ggacacgtcc tcaacaaagc agatggaatg gagtaaggtt agtgaatggt
    38401 tccatttgca tgctgccgga gaagctcttg acggttcgtg ggatgatagg caggatacaa
    38461 catattctaa ggaaacagtc aggaaggtgt ccagatggac tttatcaggg catttaaaca
    38521 ccccttggat acgcaaatgc tccagatctt caggcagaat atgtcttagc tgcagaaaat
    38581 taaaagaaat cgggctggtg ctcctttgcc gagaaggagg tcccggataa tacagattta
    38641 gtcgggcctt actcaaatcg cccagtacca tagccaaagg aaaggattct ccaaggtaaa
    38701 aaaatccagt attcatcaat tacattccgt actatctttg tggctattca ggaagtggtc
    38761 gaacatggca gaacaggaga tacctctata aaatatagta atatttatcc aagcctccag
    38821 agggctgtta gaacggtgaa tcggcaagtc cagcactatt cagcggaaga gaataatccc
    38881 tgattgacat tggttaacac agtaagtata gtgcatttcc aaaactgagg atttgacgct
    38941 gctgcagtag ttgtctggtg ggatatggga gtctggacgg gggcgacagt agcggcgtgt
    39001 tgcatgaagt gaccgtggtg gtcgacattg cgaggacgta gctttcgggt atatgtgccc
    39061 cgcctgatct tgcggggact gcaataaatt tatcactcta agcgcaattt ataaagggaa
    39121 ttcgatgctg agcatcacat ctgatgcgct tctagttaca tcacctacat gccttgcccg
    39181 ctcaaactcg cggctgagct ggctttctcg tataattctg cgctttgggc attcgtggaa
    39241 gagtttcggt aaagttgcga ccgtagactc tcaagtgtcc atcagtcttc gcaggatgat
    39301 ctgggcagga gaacattgaa caacgaagag caggcaaaca gtgggagaga atatcatgtc
    39361 tggtttatat acactattgg acatatagat gaggggatgg ttgcataaag cctgttatat
    39421 agtaagctag caacagtcac ttaactaact agggagcgct tactgccctt acaaggttga
    39481 aaatttcatc gtgcctaaag cgccagagga acccagctga agttttagaa gaaaggcgca
    39541 acactttgtt cgggagggta gtcctcaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
    39601 ggaatacaat actaatgact ccgtctacaa tgagccaggg aagtaatctc ttttgttgcg
    39661 gagaagcggg gacgaccgaa tgcagtgaac aagagcgacg ctaaccaatt tttccctagg
    39721 gtctgatctg aaccaagcag ttagatctga agtattagcc aggtgctgat ctcttgggta
    39781 atgggccgta agatgtatct atacccagct attctctctg gcttctctgg tttcccctta
    39841 cgttttcctc atcctgcgaa ttcatctttc attggacatc accgtaaaat ccttctgtat
    39901 tgtaccaaca gccttcttcc tagcgccaca cagcagcact cgtaggttca gaccttccca
    39961 tttcccggat aatacccagt ggatctgctg gacgagccgg ttgatttgta atccaccgca
    40021 tgaggaactt ccctggcgat atcctcctag agcataagcc tggtcttcct ctatgtcgcg
    40081 tcgggctgtt ctctttccat taatgtgatt cagaggacat acaccttata tattcttcca
    40141 gaagggcata tccgtgcttg ctcaactgac catgaccagc aagtctgccg ggctctccgc
    40201 agccgaaccg atatttccac aaattccacg tgtcgcccta gtcccgcaag acgatgcctc
    40261 gtccccattg tcaagtctgg agttgcattc cattgaaccg ataggggcca atacgccgca
    40321 tagtaggcgc acaaggcatg ccgggtcaac aaaaccctcc gaagtcgacg agatgttcaa
    40381 cgtcgtgcag tcagcagcag cagagaacta tggagctcaa gacacaaata ggaaaacagc
    40441 ctcgatacac ccgcgcagga acacgatctg gcgactagct agcgcgtgcc tgatgaactt
    40501 tggcaacgga atgaacgaca gtgcacccgg tgccctaatc ccttatattg aggatgatta
    40561 cgggattggc tacgccatca tctcactgat cttcatcgcc aacgccgtcg gattcgttct
    40621 tgccgcgccc cttactcaca caatccaagt ccgaatcggc cacgccaaaa gctatgctct
    40681 ctcgatgagt ctcgtcacag cgggctacgt tgccatcgta tgccacccgc cctttccggt
    40741 cgttgtcacg gcgtttctcc tcctcggctt cgggatggcg ttaagcatcg cgcttaacaa
    40801 tgtcttctgc gcaaacctaa acagctatgc cacagcactg ggctttttct ccggtgcgta
    40861 tggcatcggt ggggtgatct ccccactatt ggccacggcc atggtgtcac acggcatccg
    40921 ctggacatac ttctacttca tcacactggt gatttcgacg ttgaatatgt tgcttgcggc
    40981 tgtcgtcttt cgcaattata aggacgaagg tgccgcttcg agggcgccca ctcagcaaac
    41041 atccccctcc cttgcttctc agacggccca gccaaacgag aatgattccc ataactccca
    41101 cactcgcctc caaaccctga aacgagccat ccggaatctc acaacgatcc taggatcact
    41161 ctttatcttc gcataccaag gagccgaagt ctctatttcc ggctggatcg tctcattcct
    41221 catcaactac cgaggaggtg attcgcgacg tgtcggctac gtgagcgctg gcttctgggc
    41281 cggaattacc ctcgggcgct tcctccttgt atacccggca aaccgaattg gtgagaagct
    41341 tgccgtagga ctgctggttg tcggagcgat agcgttccag ctcatgactt ggctgatccc
    41401 caacattgtc ggcgaagcgg tggcggtggc ggtcgtgggc ttgctgctag ggcccatgta
    41461 tccatgctcg acggccgtgt ttgcgaaact actaccccgg agcattcagc tgactagcat
    41521 gagcttcatc actgcgctgg gaagtagcgg gggtgcagtg tttccctttc tgacgggtat
    41581 tctgtcacaa gaggtgggaa cgatagtcct gcatccaatt tgtttggcgc tctatgcagc
    41641 gatggttgtt tgttggtgct ttttgcctgc gatttcgaag agatcggagt agggtcgttc
    41701 gctataagtt tcgtactgaa tgtgatcaat ttcatataac tagaaataat ggtgtttcac
    41761 attgataggt cggatgatag cagacctctg tagtgtaaag aaggctgtgt cagaatacct
    41821 cagcacatta tacaaaacta aaactatata ggagttgtgc ggatgatcct gctgttacca
    41881 gtaatgttac agagtagaag ataatgcact gggtagctaa aactgtttag tcagaattag
    41941 caactactgt tctaaacagt tcaatgacca gcatgttctg gacattgtgg tgctgagcaa
    42001 ttttggtcgc tcgcgatagg catgcccagg gctctggaaa atgatgaatc attgtcacat
    42061 gaacctccac agcctgtgac aatcggcgcc gtgcttaccg taaaagtgga cgtggagtgg
    42121 ttcatcaaat cgcagagagt tcctcagagt gagcatgcac gtttggaaat tcttggcttt
    42181 cccttggccc cattcatcaa ccaatctcgg aaaatacact gcggcacttg gaaaccacta
    42241 gacagacctt ttcggccgat aggacctgga tgtggaccga gggaaccttg tcttgccagt
    42301 aacagccata acttactagt agttagccgc gtttccttcc caccgtgagc cgtggcaagc
    42361 cgcttgcgta tttctgatag ccactcagta atgatcagcc ttacgctttt gtctgcctct
    42421 tagtttctag tcggatttct cactcggagt tttgcaacac acactgtgta tgcgggccgc
    42481 catttccaca gccgagccga gtcctaccga cagtggtgga tggttccaac ctttagggct
    42541 tcgaatagtt gcagcacttc tctcccagat aacatattta atgtcataag gttccactgg
    42601 tgactttgtc ggcgcgtgta tctgtctagg ccatatgaag ccgcgtagtt cacagcatag
    42661 actgttaatc ttgccttatg agcttagaaa ccgaagcgat ggtgcttcta tcttagagtt
    42721 ttcgtggggc ataaaaggcc ccatgagcgc accagcatca tctgctggct acgccctgtg
    42781 ctgggataaa aattacccaa actagaaggt atactcattt aagttacaaa tattggtatt
    42841 atgcacatta tcacggaagc ctagagcttc cacttccagg taagatggcc actaacacgg
    42901 tcgaatccct gttccattcg tgcccaggca accgtcatgg tagatgccac tatcaacgca
    42961 ctgacaaaga tagccatatc caaatagcta cgcgaggtag tctcgccatt gtacgtgcgt
    43021 accatgactc cagacaccgg ggtgcccacc aacccagccg ctccctgcac catgtacatg
    43081 atacccgtga tacggggcat ctcctgcaaa ccaaagagtt ccacgagagc cggcgagaac
    43141 agcccaatat aggcactagc gaagagaccg tagaaaatgg tgaaaacaat gaagcagccc
    43201 ttggccgcca ccaggtcatg caacgtggac ccaagcaagg tactggggat ccagagtgcc
    43261 accgcaccca cagcactgag aagagtgacc aggaagaagg aattcaatcg cccaatatag
    43321 tcagccaggt acccgatggc gaccttaccg atggcattgc acgcattgct gagagaggtc
    43381 cagttggctc cctcggactc gctgtagccc aacgtctgtc cgtacgacga gatgtagtag
    43441 atgggcgtgt agtaggctgc gctctgaaag gctgcgttga gcacctgtgc gatgaatttg
    43501 cgctggcgga ccagagacca aggaggcagt gggaactgga atagtcgaga cactaaggag
    43561 ggcttggctg ctacttcctc ctgcaagcgt tgctccatag cgggctccca taccagcaca
    43621 gcacccgaag cacaaatgag cagtgctgac aagcaaccca ccaagcggag tgtatcacgg
    43681 aaacccatag tatcgataca ggcctggatg acaggggcga agaccagacc gccaataccg
    43741 gttcccgcag agataatgcc aagggcgagt ccgcggcgct ttgagaacca tgtgggcggt
    43801 acgatcatcg agggcatgta ggaaagacag ctgccgatcc ccagaagaag gccttgagag
    43861 agttgaaaat gccaggatgc tgttccaaag ctggcgagaa tatttgctaa cccgaatata
    43921 agtcctccta cgcatacaat aatgcgagga ccaaaacact tgcaccatgc caccacgaag
    43981 ggggcgccaa gcttcatcat ggctgatgac aagctcccaa tcaatgtaat ctcggcggat
    44041 gaggatccgg tgaatgcagt gtccttttgg gtggccatct tctcgtactc agcttggtaa
    44101 actccgtagg cgaagacaac tccacagccg gtgaagttga gcatgaatcc ggagaggaca
    44161 atgaggacat attgcctaag caggtcagaa ggagccgagg gcaatactag cagttgtaag
    44221 gttgccgtac ctccgcgagt gcttgttctt gggagcctct gtgggcggat gctgttcggc
    44281 actggctggt gcgttcatcg tcttgggcag tgaagccgag accgtatatg gctattggtt
    44341 attcttggct ttctttaagt tgagacactg actagtcgta tatagtaaaa tctgcgccag
    44401 agcatatggt catttatagc atgtctcata gtgggcgata ttatgccgtc tcggacttgg
    44461 tctactgctc cccgttcatt atcgatctcc aaattacagc cctgatgatt gtttggtcca
    44521 tggttcagtt tgctgctaac tttaacatgt acagttgcat ctccgcgggc tcttccttgt
    44581 tctgtctttt ttgttgcccg aaaactattt gaatgactga aacctcggcc tttcacgaaa
    44641 agactgagag atccaactgc aatacagtat attactgtca ttttctgggc ctatgtgcca
    44701 cggttgccgt cggccatctg attttgcctc attgttccag gcggggaagt ggagaaggga
    44761 tgcggtccct gaaaattaca cactcgacag tttttgcagg tggcgctttt ggattcgcaa
    44821 cgctatacca tatctggtta gcctcgttca ggtactcccg aaagggctag gctcggtagt
    44881 gaatcgccga cttggcagtt tgggattgtt accatttctt ctccgctaac tatctatagc
    44941 tagtctaatg agagtaaagg tgcaacccgg tctgcaacca ctcggagctc ggacagaatt
    45001 gctggtctta gatactctag agtcatgtac ctgatatgat acctggttgg accttccata
    45061 tccagtcggt aaaatatggg gtcatgtggc aagtgggaag aacttttccg gtagagttcc
    45121 gtaacattcc ataccctgga tcgcattgta acctcaagtc gcaatagtca ccctcttggt
    45181 aatccgttta acccctaggg ctagagacag tcaagcagag ccgtccacac taagatttga
    45241 gtcactcgac atcatcttct cacttcccag ttcctctaag catcccaatt cattccagca
    45301 tcttcctttc tctctgtcct caccagctcc aacataccac aaaatgtcac tcataccaag
    45361 cgttgacagt gctctcgacg caattggaaa cacaccatgt gttcaattga cccgcgtagt
    45421 acctcaggac tgcgctcgag tgttcataaa gctagaaagc ttgaatccta ccggctcgta
    45481 caaggaccgc atggctctct ctgtcatcga ggaagcggag cgtcgtaatg accttcgtcc
    45541 gggaatgaca gtcgtggaag ccaccggcgg cagcaccggg tcgtccctcg ccttcgtctg
    45601 cgccgtcaag ggctacacct tccgtgtagt ctcctccgat gcctttgcga aggagaagct
    45661 taacaccatg actgcgtttg gggcgcacct ggacatcgtg ccgagtgaga atgggaaaat
    45721 cacaccgcaa ctgattccct ctatgcgaga gcgagcacgc cgtattgcca cagaggataa
    45781 agatccttct tcttattact acgccgacca atttagcaat ccagatgtct ttccaggtta
    45841 tgaaaccctt ggtcgtgaga tactagcaca ggttggagaa cctattgacg ccttttgtgg
    45901 cgcggttggg ggcgcaggga tggtgatggg tgtcgggaaa actctgaagc agagctggcc
    45961 ggcgtgccat gtagctgtgc ttgagcctgc ttcggcgcct gccttgacca agggccatgg
    46021 cggcgagcac tcggtggaag gaatcggtat tggattccct cctcctctac ttaacaaaga
    46081 ctggtatgac gaggcacggg cgattgatga gagggaaggg cgttccatgt gtcgacgact
    46141 agcgagggag gagggtcttt tggttggcac ttcttcgggt cttaatgtgg tcgccgcgat
    46201 acagttggct aaggaactgg gtcctgggaa aacagtggtg actgtggggt gtgatactgg
    46261 tctgaagtat gttcgaggaa acctgtacac agatagctga aagtgatcac cgggccgaga
    46321 cttgtgtcaa gaatgcaatt tccttctact gacgtttcca ttacacttat ccaactggtc
    46381 agggcttcat aaaccaaaca tgaaagttgt tgcaaatttt gaaacaaaac cttaactcgt
    46441 ggt
//
