LOCUS       NKJJ01000004.1         23786 bp    DNA     linear   PLN 19-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   NKJJ01000004
VERSION     NKJJ01000004.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 06:54:43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 150044
            Orig. end    :: 173830
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23786
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[160044:160067](+),
                     [160129:160229](+), [160288:160641](+), [160692:160863](+),
                     [160914:161199](+), [161246:162012](+),
                     [162903:163830](+)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(10001..10023,10086..10185,10245..10597,10649..10819,
                     10871..11155,11203..11968,12860..13786)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..23786
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23786
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            complement(2592..3845)
                     /locus_tag="CAN33_0335"
                     /product="CoA-transferase family III family protein"
     gene            complement(2592..3845)
                     /locus_tag="CAN33_0335"
     CDS             complement(2592..3845)
                     /codon_start=1
                     /db_xref="InterPro:IPR003673"
                     /db_xref="InterPro:IPR023606"
                     /db_xref="PFAM:PF02515"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189:L-carnitine dehydratase/bile acid-inducible
                     (Score: 346.4; E-value: 3.1e-105)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_0335"
                     /note="EggNog:ENOG41; GO_function: GO:0008410 -
                     CoA-transferase activity [Evidence IEA]"
                     /product="CoA-transferase family III family protein"
                     /protein_id="ncbi_CAN33_0335-T1"
                     /transl_table=1
                     /translation="MPNTRPLVRAACHNLSGMRHASTSATKKAGPLAGITVVSLEQAIA
                     APFCTRQLADLGARVIKVERPGVGDFARNYDTRVNGLASHFVWTNRSKESLALDLKKPS
                     DHSVLMRLLGRADVLVQNLAPGASARLGLSYDDLKAAHPSLIVCNISGYGPDGPYRDKK
                     AYDLLIQSEAGMLSVTGTGKEPAKVGISIADISAGSYAYSNILAALYQRERDPSKRGCN
                     IDISMLESMVEWMGFPMYYTYENAPGPTPAGASHAAIYPYGPFETGDGTVMLGIQNERE
                     WAKFCDIVLGQPSLATNERFVNNSLRSQNRDELKKIICDVFSSLSAEQVIARLDAAAIA
                     NASVNDMQGVWNHPQLKARQRWTDVKTPAGSVPALLPPGMTMGDEDTYGARMDAVPDVG
                     EHNKAILAELGLDEGTEK"
     mRNA            join(5984..6108,6163..6750,6802..6897,6956..7240,
                     7294..7459)
                     /locus_tag="CAN33_0340"
                     /product="major facilitator superfamily protein"
     gene            5984..7459
                     /locus_tag="CAN33_0340"
     CDS             join(5984..6108,6163..6750,6802..6897,6956..7240,
                     7294..7459)
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1137:Major
                     facilitator superfamily MFS 1 (Score: 361.5; E-value:
                     7.3e-110)"
                     /gene_kind="transport"
                     /locus_tag="CAN33_0340"
                     /note="EggNog:ENOG41; GO_component: GO:0005887 - integral
                     component of plasma membrane [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="major facilitator superfamily protein"
                     /protein_id="ncbi_CAN33_0340-T1"
                     /transl_table=1
                     /translation="MSEPKNQPVEEPTIPPEEGVKGWLTVAGSFCALFSSFGFLNAIGV
                     FQTTYQQTSLKDYDASDISWIFAVQLALMWAPGPLWGRMIDTYGPIPVLWPCSILCVLG
                     LCMTSLAHEYYQIFLAQGLCFGIGAGGVFTSAMICVGQWFVRRRGLATGIAVSGSSLGG
                     VIFPIFLDRVINDIGFYGAVRYTALFVGIMLAIACLLIRSRLPRKEWNGKAAWVDLTLL
                     KDTAFGLYTAGAFFIMWGLWAPFDYISSMAENAGFSSTLALYLISIINAASIFGRLIPP
                     QLADVFGHFNVLTLCCFGTGVSMLCLWLPFNYHPSHAGIIVFSAVYGFVSGAVVSLMMP
                     CVAKVGDLQTLGQRFGTFQLIMSVSCLTGLPIMGAILEKQNYTDYSGLQLFGACCGILG
                     SVLIGAATFLLRKMRNTSKI"
     mRNA            join(7966..8768,8818..9043,9100..9303)
                     /locus_tag="CAN33_0345"
                     /product="Ring hydroxylating alpha subunit (catalytic
                     domain) family protein"
     gene            7966..9303
                     /locus_tag="CAN33_0345"
     CDS             join(7966..8768,8818..9043,9100..9303)
                     /codon_start=1
                     /db_xref="InterPro:IPR001663"
                     /db_xref="InterPro:IPR015879"
                     /db_xref="InterPro:IPR015881"
                     /db_xref="InterPro:IPR017941"
                     /db_xref="InterPro:IPR036922"
                     /db_xref="PFAM:PF00355"
                     /locus_tag="CAN33_0345"
                     /note="EggNog:ENOG41; GO_function: GO:0051537 - 2 iron, 2
                     sulfur cluster binding [Evidence IEA]; GO_function:
                     GO:0016491 - oxidoreductase activity [Evidence IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_process: GO:0044237 - cellular metabolic process
                     [Evidence IEA]; GO_process: GO:0055114 -
                     oxidation-reduction process [Evidence IEA]"
                     /product="Ring hydroxylating alpha subunit (catalytic
                     domain) family protein"
                     /protein_id="ncbi_CAN33_0345-T1"
                     /transl_table=1
                     /translation="MWRLLGRSSNTSEKSSPPRSLPGSWYRSDAMYQLERRAIFSKRWM
                     LLTHSSRLTKPGDFLSFTISNFSFFLTRDREGSINGFHNICRHRAYPVVQARSGATSIL
                     SCKYHGWSYGLKGNLSKAPRFETVSNFDKSQHGLLPIHVHIDKAGFVWVNLEAGDPEVK
                     WEDDFQKIDEQPRMQDFDFDGEYTFDHYWEMDVEANWKLLIENYNECYHCATSHPLING
                     VSDLPRYRVEPKARYMEHHIFNKDNIDAQFRRSITYFYPTTSVTVTDKFFYIQRMIPVS
                     ATMSKIENEVYRHRDATDEEFANINAFYRQVLDEDRDLCVGAQENLSAGVFINGELHPD
                     KEKGPIHFQDHVKTMVMEHRRKEEEQGGEEIWPAVPKVTGEMRTGKLAEEERFCSQLEA
                     ASCMARSELAW"
     mRNA            join(10001..10023,10086..10185,10245..10597,10649..10819,
                     10871..11155,11203..11968,12860..13786)
                     /locus_tag="CAN33_0350"
                     /product="Squalene/phytoene synthase family protein"
     gene            10001..13786
                     /locus_tag="CAN33_0350"
     CDS             join(10001..10023,10086..10185,10245..10597,10649..10819,
                     10871..11155,11203..11968,12860..13786)
                     /codon_start=1
                     /db_xref="InterPro:IPR000537"
                     /db_xref="InterPro:IPR002060"
                     /db_xref="InterPro:IPR008949"
                     /db_xref="InterPro:IPR017825"
                     /db_xref="InterPro:IPR019845"
                     /db_xref="PFAM:PF00494"
                     /db_xref="PFAM:PF01040"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="CAN33_0350"
                     /note="GO_component: GO:0016021 - integral component of
                     membrane [Evidence IEA]; GO_function: GO:0016872 -
                     intramolecular lyase activity [Evidence IEA]; GO_function:
                     GO:0016765 - transferase activity, transferring alkyl or
                     aryl (other than methyl) groups [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]; GO_process: GO:0009058 - biosynthetic process
                     [Evidence IEA]"
                     /product="Squalene/phytoene synthase family protein"
                     /protein_id="ncbi_CAN33_0350-T1"
                     /sec_met_domain="phytoene_synt (E-value: 3.1e-20, bitscore:
                     68.1, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MGLDYVILHCTYTIPAASALTVLYYPFFTAQDRCKICILITIAIL
                     ATLPWDSYLIRSAIWTYPPDAVVGLKILDIPIEEVFFFAIQTYITSLTYCIFTKPLVRP
                     MYLRSHLERRGTRYVVATVILALMGGGTACLLLGRRMTYLGLILVWACPILLFQWMMSY
                     PFLSELPWKPTITSICLPTLHLWFADSRAMGTGTWRIEEGTKLNFRIGGLELEEALFFL
                     VSNMMVVLGLVGCDYAYALQEYESLSQPASDVYITLRKALSLLARPLPIDASLISALSQ
                     AVYRLQEKSQSMFLGSALFQGQLRIDLIFLYSFCRVMDDLIDEAEDEQEARFWVTECRH
                     LLDSTHRSEPHSDHFYTGKKGEEHERLRQSISYLPPSHLSNDSFDDLLKGFEIDLKFNP
                     QREAFPIQSEYCLDQYAGFVAGTVGVLVFDLTLFHCGHYFIQDVPRLRRAAKDMGKAMQ
                     CINIARDIHRDAAIGRVYIPTTWLGEVGLTPGDVLQCPNSPVTYDLQERMLQKADEYYQ
                     VSRGAMEELPRGVREPLRATVASYMDIGLLLRERKGTSLAQASKMKVPLEEWSWKDLVL
                     TIWLFTADDFTTFVIPETAFGICAALSGPLLTDDNTPDLLSVVSRIPIVMLWNWLNLFV
                     FNLANQRHPDSVAEDKINRPWRPLPAGRISILQTRRLLLLAIPMVLASSVYLGAWEETA
                     LLYTLNWVYNDLSGGDDGFILRNVLLALAFSQYNKGSLRVATGTGFDILPRAWRWIWVT
                     SAVIGTTMHIQDIKDVEGDRAKNRRTMPIVMGDGPARWSVAVPVAIWSVVCPAFWELDV
                     ARYVLPVAVGMTIAGRILLLREKAADKRTWKMWTAWTAVIWVLPLFKNASVFVRFGKKL
                     GVV"
     tRNA            13994..14064
                     /locus_tag="CAN33_57420"
                     /product="tRNA-Gly"
     gene            13994..14064
                     /locus_tag="CAN33_57420"
     mRNA            complement(join(14635..15821,15874..16073,16127..16257))
                     /locus_tag="CAN33_0355"
                     /product="Aldehyde dehydrogenase family protein"
     gene            complement(14635..16257)
                     /locus_tag="CAN33_0355"
     CDS             complement(join(14635..15821,15874..16073,16127..16257))
                     /codon_start=1
                     /db_xref="InterPro:IPR015590"
                     /db_xref="InterPro:IPR016161"
                     /db_xref="InterPro:IPR016162"
                     /db_xref="InterPro:IPR016163"
                     /db_xref="InterPro:IPR029510"
                     /db_xref="PFAM:PF00171"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 505.1; E-value:
                     2.4e-153)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_0355"
                     /note="GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]; GO_function: GO:0016620 - oxidoreductase
                     activity, acting on the aldehyde or oxo group of donors,
                     NAD or NADP as acceptor [Evidence IEA]; GO_process:
                     GO:0055114 - oxidation-reduction process [Evidence IEA]"
                     /product="Aldehyde dehydrogenase family protein"
                     /protein_id="ncbi_CAN33_0355-T1"
                     /transl_table=1
                     /translation="MADSLFVDITTPNGRQYQQPTGLFINNEFRPSSSGQTIVSLDPAT
                     DKPIATVHAATAEDVDAAVQAAKAALSHPSWKLLPATERGQLMGRLADLMEENRALFAA
                     IDAWDNGKPYHVALTEDLTEAITTIRYYSGWADKTFGQTISTTPQKFAYTIRQPIGVVG
                     QIIPWNYPLSMATWKLGPALACGNTVVIKAAEQTPLSILVLATLIKKAGFPPGVVNVIN
                     GYGKEAGAALVQHPLVDKIAFTGSTATAREIIKMAAGTLKNITLETGGKSPLIVFPDAD
                     LEQAVKWSHFGIMSNKGEICTATSRIFVHRSILASFLEKFKKEIETTSKIGDQWDENTY
                     QGPQVTRAQYERVLSYIETAKKEGATLVTGGKAYTPKDEKNAKGYFVEPTVFTDVTDDM
                     RICQEEVFGPVVVILPFDSEEESVRRANDTTYGLGAAVFTTDLERAHRVAADIEAGMVW
                     INSSQDCDPRVPFGGVKQSGIGRELGEAGLEAYSQVKAVHVNMGSRL"
     mRNA            16860..17780
                     /locus_tag="CAN33_0360"
                     /product="Dihydrodipicolinate synthetase family protein"
     gene            16860..17780
                     /locus_tag="CAN33_0360"
     CDS             16860..17780
                     /codon_start=1
                     /db_xref="InterPro:IPR002220"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="InterPro:IPR020624"
                     /db_xref="PFAM:PF00701"
                     /locus_tag="CAN33_0360"
                     /note="EggNog:ENOG41; GO_function: GO:0016829 - lyase
                     activity [Evidence IEA]; GO_function: GO:0003824 -
                     catalytic activity [Evidence IEA]"
                     /product="Dihydrodipicolinate synthetase family protein"
                     /protein_id="ncbi_CAN33_0360-T1"
                     /transl_table=1
                     /translation="MTVTQQTPALHGIMVALITPFTDDKTQIDAARLKSHIDHLIGAGV
                     HGLVPGGSTGEFTTMTREERKQLTELCVEYAAGRVPVVAGTGSTSTEEAVDLARHAAQA
                     GAAAVMVVPPFYDPLNVEQLTELMSEIHEASQLPIVYYNIPSASGLTLTPQQIADLSKV
                     GVKYLKDTSGNAPAYTELVFGLSDQITAFNGWDTLTFYGLAAGSPGAVWGAANIIPELA
                     VELWNAVSVEGDLKKGRELWAKAWPICKFLESHNYAAAVKTGVELRGQATGGLRKPFAL
                     LKDDLQSELAQLMVNANVNVVKRSS"
     mRNA            complement(join(17869..18912,18962..19897))
                     /locus_tag="CAN33_0365"
                     /product="Fungal specific transcription factor domain
                     family protein"
     gene            complement(17869..19897)
                     /locus_tag="CAN33_0365"
     CDS             complement(join(17869..18912,18962..19897))
                     /codon_start=1
                     /db_xref="InterPro:IPR021858"
                     /db_xref="PFAM:PF11951"
                     /locus_tag="CAN33_0365"
                     /product="Fungal specific transcription factor domain
                     family protein"
                     /protein_id="ncbi_CAN33_0365-T1"
                     /transl_table=1
                     /translation="MSDALSADLVSGSIDASLAEIETRSRDTERPSQGDIVVGPFAVLD
                     FSLTEPKSASRAHPTDETTVANDVILPSGDTLAEGASGVSPALSQESIAYMNDLLQWSD
                     ILSLDPQLQSATLSGTFDLGDWLPLDLGTQAPMLEHNLLGEAPSLMDDTAALYHCVPGQ
                     DNASKMVPPVDSNPPDVLADAHYLLRHFQDHVISRMMAVPLDQKSPWKILNVPSAVVTY
                     SDITFLGSQNITHARLANLYCLLACSALHLTVNPSMRTSDSTERWKPVAEYAYHLAKDH
                     MQMSLKHETQEPKKAKYKDQLMAICALTEFAILSSQQQDARCYMIDAERLLRLRGLPKQ
                     RISQKARLLHHTYTWLRIVGESTYALHNYTPSDAFMEALKYRFRYQKVENTQAAGYRTS
                     RLDDFLRLDRRPSDSDLDIDEPKEDDVGLYDIHLQDSRKYPATLYSQIYGVSETWLSLV
                     SQTTRLANVMETFRVAREMRQGNNASLEAWEALHRRSARLESMVCTFASRRTEDNICDS
                     TNILAKSHGCLLQALNSALVIFFYRRIRQVHPAILESQVDKVISSLNEFDVALVEADHT
                     GPGTVWPLFIAGCEATTPERRQSITLLLDKGEARCGFSAYHTVRDVMNQVWDKQDAHFT
                     RSRGETFPTWLDVVKSKQIWPILA"
     mRNA            complement(join(20611..20868,20929..21392,21445..21522,
                     21581..21786,21839..21855))
                     /locus_tag="CAN33_0370"
                     /product="NAD dependent epimerase/dehydratase family
                     protein"
     gene            complement(20611..21855)
                     /locus_tag="CAN33_0370"
     CDS             complement(join(20611..20868,20929..21392,21445..21522,
                     21581..21786,21839..21855))
                     /codon_start=1
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF13460"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 34.2;
                     E-value: 3e-10)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_0370"
                     /note="EggNog:ENOG41"
                     /product="NAD dependent epimerase/dehydratase family
                     protein"
                     /protein_id="ncbi_CAN33_0370-T1"
                     /transl_table=1
                     /translation="MAKIFLTGASGYIGGDVLHALKSALPTCQYTVLLRDEAKAQKLSQ
                     AYPDVQVVLGDLDASSTLEQQAREADIVIHTASSNHVKSAEAIARGLTAPERPKPGHWL
                     QISGASVLSIPDIVASAFGGPSNKIYSDVDGADELRELIRQYSAKRVVDNLVLSLPHTS
                     SRPKTALIFPPIIYGRGRGPINQRSIQIPELARVTMQRRGGVQVGRGEATWSNVHISDV
                     SNIFVKLAEKALQSEEGKLWNENGLYFPGSRAISFGSISARVAQEVKKLGLAESESVTE
                     ISHEEADSLTPHGGVLWGTNAQQVAQRAAKYLKWVPEGRTLEEEIPHTVLAEAQRLGLK
                     "
ORIGIN
        1 gagaagggaa aacatccggg gtggcggaga caagatcacg gctctcgagt tttggggagg
       61 gagcagtggg atcgaccggt cgcagagtgc gggccgtgcg atcgtccaaa catcggaaga
      121 acaggtttag tacccagttc tccaagtccc aagatttttg cagctcttgt aggctcaaga
      181 gacagagccg ggctcggtgt tccgccaatt tgcgacctgt cccggacgtg cgacggaaat
      241 gaatggtgtg gatgcagagg gttgaaaacg cgtgtgtgat tctacatggt cagcttgaat
      301 cctctatagc atatcggcgg ggacggtctt acagatgagg agggccgtgt tggaccaagt
      361 tgtgcgaaag catatcctcc aacactcgtg tacttttcgt cgcggcatcc aaggctatct
      421 gaccttgact atccagatct ccatcaggag ggtgaagaaa ggacggtcgg taaagcagga
      481 tgtagagatt tctaatggca ttcgatcagt gaaatacact caagtaccca atacatgcca
      541 cctactggta tgtcatatgt aagagtccgg ccagaaactt ggctcgtgga gttgtggcat
      601 tttccagctt cagctcaaga ggcatattgg cttcccagtc cctcagttgc tggtgcaatg
      661 ccgctcgtga cgcaccgtta gatgacggac ccagcggcga gtactgggtc gagacaatag
      721 aacgcactga acagtgagca aagattcgca gtatggaggt tcggacatac ataatttggc
      781 taactttgcc atttcggctg gataagagag gtcttcgata cactgcaccc caaaatgact
      841 ttggccgccc acagcctcct ctcggatatc ctcaggctct agcatgtcga catcgcagtc
      901 ttcgtcccga atgtgtggcg gaagcccaag tgctgcggcg ctttgctggt ctcgggtcta
      961 gcaacggtca gcatctacat caggcttacg agaggtgaca tacgtaaagc gaccaccaaa
     1021 tccgcttcca tagacctgcc tctcgacggg aggcaaacgg gaatttggac ctgactgagt
     1081 taacaggaga cagggtaaga caaaagaata catacatcaa atgcatgccg cgcttttgtg
     1141 ccaggtcaat ggcaatgcca agccagaatc gaatgtcccg ctcctcagat ggtcctccac
     1201 gccagaagct caacaaaaac agcgcttgaa tcttgaccgt cttgttagac tcccattcag
     1261 catcgtagat tgcctttgct cggctgtaaa agagaaactt ggcccagtat cgaacagaaa
     1321 actccgtccg ggcaaacacc tcatccgtgc aaaggctgac gcctatgaac agtatcgcct
     1381 ggagtaagag gggcgacatg ctcccctgca catagctctc atacaccgca gcacaatcaa
     1441 ggattgggaa acaggggtga aaccagtcaa agtacgcccg cagaagagtt tcgcatgtct
     1501 ctggcggcgg gtacgagaag gccccatcag ctctcagctg gccttcctgc ttgatcttgt
     1561 gtgctcggaa agcctcatca cgggtgttga aggcatcaag tttctcagga atggcataat
     1621 gaaagcgagt catatgcatc tcattagttc ccttttcagg cgaccggcgc ccttcgtcaa
     1681 tcactacagt gagtggactc gattcaccaa agaacactgt tggatgcgca ctcgcagcat
     1741 cccctggtat cgggtgaaca tgcgactctt ttgcgtcgga tttatcacct gctgacacgg
     1801 tgaatgaatg gttccctccc ttcgcagatg atgccggcaa ttggaccgag ttgccgtcgg
     1861 tttgttgccg agcactcttc ttacggggat acctaagcca ttgaatcagt ctacgccaaa
     1921 ctaccataat gacgaaaccg tgaaaacata ctttcctcgc tttgaaacgc ctatctcaca
     1981 gggtacattc aatgccagac aattctggca tgggcgcatc tgtagcacat tgcagcggat
     2041 tcgccgctta ttgcagtgga gacaagcctg cttggccctg gttcttacct gtcggtggcc
     2101 cgatgactcc tgactggaca tgatcctcga attagctcca attaccaatg aaagagatcg
     2161 tccacagtgg agttcagagg tggccaggca gaatgcaagt agccgtagtc gaggataaag
     2221 cggctttatg ctgcctcggt cttggcgggc atgtcggctt tttgcctgtt ttcccgatcc
     2281 acttgcttcg gcgatgggta tattgcgccg atattcactt tacgctggat accgtcgcgg
     2341 ggtgatatta ggggcagcag gggtaggttg cctgaattgg attaaactgt aagatccata
     2401 ttgtggtcga ctagttctac gtctgaacat cctttgacat gcaggtatct tcaacctcgt
     2461 gagtggacag tagaattgcc cgaggtgaat ccatcgcact gagttattta caaagggcct
     2521 aaaagttcca atactcgcaa ggatagccaa gtccactagc tcaactgtac atgtcattaa
     2581 ttcaactgca gctatttctc cgtaccctcg tcgagcccca actcggccag aatagccttg
     2641 ttatgctcac ccacatcagg gacagcgtcc atgcgcgccc cataagtatc ctcatccccc
     2701 atggtcattc caggaggtag cagagccggc acacttcctg cgggcgtctt aacatctgtc
     2761 catcgctgcc gagccttgag ctgtgggtgg ttccagacgc cttgcatatc attgacgctg
     2821 gcattagcaa tcgccgctgc atccagtcga gcaatcacct gctccgccga aagcgacgag
     2881 aagacgtcac agattatctt cttcaactca tcacggttct gcgagcgcag cgagttattc
     2941 acaaaccgct cattcgtagc aagactgggt tgacccaaga cgatgtcaca gaacttagcc
     3001 cactcacgct cattctggat ccccaacatc accgttccat ctcccgtctc aaacgggcca
     3061 taaggataga tagccgcatg cgaagcaccc gctggtgtcg ggcccggggc attctcataa
     3121 gtataataca tagggaagcc catccactca accatgctct ccaacatgga gatatcaatg
     3181 ttacaccccc gcttcgaggg atccctctcc cgctgataca acgccgccag gatattggag
     3241 taggcatagc taccagcgga aatatcagcg atggagatgc ccaccttggc gggctctttt
     3301 cccgtccccg tgacggagag catgccagcc tcgctctgga tcaacagatc gtaggccttc
     3361 ttatcgcggt acggtccgtc aggaccatac ccggagatgt tgcacacaat caaggatgga
     3421 tgagccgctt tgagatcatc gtaggataaa cccagtcgag cactggcgcc gggagcgagg
     3481 ttctggacga ggacatcggc gcggccgagc aggcgcatga gcacgctgtg atcggacggc
     3541 tttttgaggt ccaaggcgag actctcttta gaccggttgg tccagacgaa gtgggaggct
     3601 aggccgttaa cgcgggtgtc ataattgcga gcaaagtctc cgacgccagg tcgttcgact
     3661 ttgatgactc gggctcctag gtcggctagt tggcgggtac agaagggagc ggctatggct
     3721 tgttccagac tgacgacagt gatgccggcg agggggccag cctttttcgt ggcgctagta
     3781 gaagcatggc gcatgccgga gagattatgg catgccgcac ggacaagggg acgggtgtta
     3841 ggcatggtgc tggttgtgaa ttggggatat tttcgtgggg gatgaccccg gtttttgagg
     3901 ccatcgtcga ccggagaacg tcgccgaccg tggggtcgcg ggctctctgg ggtcggttat
     3961 atgccccggg ctggcctcgg tcccaccatt agtttattgg gagatgatgt actataagag
     4021 gatgaaagtc ctgccctgat cattttccag aagaacaatg aaatctccag aagatatgta
     4081 tcaggcaaag tgtgttgttc ccaaagaact agatatcctt ccaccctagt aacaatctgt
     4141 ctgcaaagat tgtgatagca ggtattgaaa catttttgct attcattgca tctcaaggct
     4201 tgatcacggc ctatcttctg ctaattgttc attcacagct tttcccagct tgagcatggt
     4261 tgtaggaatg atactggaat ctccatctcg cagtcaatcc atcaatgatt cggttactaa
     4321 tttcgcgcgg tcgcataagg tctactacca gaattcaatc acggcctgct tatttctgat
     4381 cgtagcgagg gctttagaaa ggttatatag gaattgaatt gccgcattac gaaggagcaa
     4441 tgtgctatga ggcctggtga ccatagctta ttccagccac gtcgctagca tgccacttgg
     4501 aaaacgatca cccatataac tgcgcagctc gaactcacaa gttctagaca gctacctata
     4561 tgcaaaccga caaggatact ccctgccaaa tacagccacg gggctattcg gctgaacacc
     4621 tgctggatac cgccggaggt gatcctggac gatgttcatc ccaatgcaag caccctggag
     4681 gcttttggtc taatatgctg tactactgca cctcgtatgc gaccaaatac cggagggtcg
     4741 tcataacggc cattgctgat gtcggtcact tacaagggac acaagcagcc ttaaccccca
     4801 attgtgaagc tatactactt aaagacggga aggtcacact tgaacatctg ttcctgaagt
     4861 agctcggttc aacgggctag tattcccatc cagcagatgg ataatggctg ttccatcggg
     4921 gaggacggca tcgtccaggg aactcgcttg acgatcatcg ggctagcatc aggcctccct
     4981 ggcgtctgat tggtggggtt aatgtgccgt tcacgtcacc aactttgaga cggggaatat
     5041 tccgatgaat gagacgtgcc tttttcatgt cggtgtgcag ccgcaagcag atgtttcgga
     5101 tacatccgaa attctccgat cagaagcatt tgtgctatga cctgagcaga actgatgccc
     5161 aagtcaatac tcggtctgca ttctttagtg cggacggaat tgtaaatcta ggccaaactg
     5221 aggactggcc gtgaagggta tattagcgaa tcatattgcc cgctgtcgat atgaatcaag
     5281 tgtcgcatga acacgtccca atgtccggcg cagcctgccg tagtccatga agtccgctgc
     5341 cctgtacatt gatccggcag ttggcatcag agtttaggta tcctgcggta gttcagcaca
     5401 gtggagccat gtgggccggc atcatcccaa taatgggttc gagagtcctc cggccagggt
     5461 tccctggtgt agcttgctcg cagccgcttt gtgggatcca gcaggtcgcg agcggaagaa
     5521 aaaagactac cagttgaatg ctcctggttg ctgtcatttg gctccagctc atcgtccgac
     5581 caatgtccac agcatatgta ttttctttta ttgaagattg aacgggtcag atggcattct
     5641 gccactgcga tgacacggtc aatttcatgc ccaaagcgac aagcgttcgc ataattagcg
     5701 cgaccctggt gagccaaatc cttgtcgtgt tcgccccatc ggacataacg agagccgagg
     5761 gtccgaggcg aagcttctca tcgaaaccca gatacttatc ttagcgcccg cttttattcg
     5821 gtcggactta gccagtcgta gaccgaatcg ctgtccggag ggaccctgtg gaggcttttc
     5881 cctccagaat ttgtcattcg cttcatgcat cttcaaatat ttgacaaggg ctctacatat
     5941 attggaggga atatctgctt gagagttctg ggcaagacaa accatgtctg agcctaagaa
     6001 ccagccggta gaggagccaa ccatcccgcc cgaagaaggg gtcaagggct ggctgacggt
     6061 ggccggaagc ttttgcgccc tattctcctc ctttgggttc ctgaatgcgt atgtatagcc
     6121 tgggtgaatt tgcccaccta cttcatactg accttatcac agtatcggag tcttccaaac
     6181 aacatatcaa cagacgtcgc tcaaagatta cgacgcgtcc gacatatcat ggattttcgc
     6241 cgtgcagctg gccctcatgt gggcgccggg accgctatgg ggccgcatga ttgacactta
     6301 tggcccgatc ccggtcctct ggccatgcag cattctctgt gtgctaggac tttgtatgac
     6361 tagcctggcg cacgagtact atcaaatatt ccttgcgcaa ggcctctgct tcggcatcgg
     6421 agccggtggt gttttcactt cggccatgat ttgcgtcggc caatggttcg ttcgccgccg
     6481 aggccttgca actggcattg cggtatcggg aagttcactt gggggtgtta tctttcccat
     6541 attccttgac cgggtcatca atgacatcgg cttctatggt gccgttcggt atacagcgct
     6601 attcgtcgga attatgctgg caatagcctg cctactgatc cgcagccgtc ttccgcgcaa
     6661 agagtggaac ggtaaagcag cgtgggtcga cctgactctg ctgaaggata ccgcatttgg
     6721 attgtacacc gctggcgcat ttttcatcat gttcgtcatt cgttcctatc aatggcctta
     6781 cccatccact gacagtgaca ggtggggtct ctgggcccct ttcgactata tttccagcat
     6841 ggcagagaac gcgggatttt cgtcgactct tgctctctac ctgatttcta tcatcaagta
     6901 aggttgcgca aaacctttcc tcgcatctat gatggctgac tcctgtggac ttcagtgccg
     6961 cctccatctt cggacgtctc atccctcctc agctagcaga cgtgtttggt cacttcaacg
     7021 tcctgacact ctgctgcttc ggtactggag tgtcaatgct ctgtctttgg cttcctttca
     7081 actatcaccc ttcacatgcg ggcattatcg tcttctcggc ggtctatggc ttcgtcagtg
     7141 gcgcggttgt ctcccttatg atgccatgtg ttgccaaagt gggagatctg caaaccctgg
     7201 gtcagcgatt tggaacattt cagctaatca tgtcagtaag gtgagtatca gacctttaag
     7261 caagtcaaat ttaccggttg ctaactttgg cagctgcctg accgggttgc cgatcatggg
     7321 agccatactc gaaaagcaaa attacacgga ttactcaggg ttgcagcttt ttggtgcttg
     7381 ctgtgggata ttagggtcag ttttgatcgg agcagcgacg ttcttgctca ggaaaatgcg
     7441 gaatacgagc aaaatatgag ttgagttggt ggctatcccg ccagccggaa aaagaagaga
     7501 agagaagact ctggtcgttg ggacaggacg atgtgagtcg cataaaaatg acttgaacga
     7561 cttatacatg taataaatag cataatatag acaggaccct ttggcactca ccaaagatag
     7621 acatggttga ttgtttgaat tgtatcgaaa aatcccgtct gtggcccaat gtggcgatat
     7681 gcagcagcga ctagcaagtg aaacaggata agcacccatg ttattctatc gtttctctca
     7741 gttggttgac agccatcgtg gcagcagaaa gatatgatag ataagccgat gatccttatc
     7801 caatggctta tcagtggtgt cctcggacga gctcccaacg cccccatctc tgatgctgca
     7861 acgccgaagc cgagacccca cttaccagca cttctccatt atatagaaac agcgacaatc
     7921 agagctcctc cgagctgccc gaacaatttt ctctcgtccg acagcatgtg gcgactactt
     7981 ggccggtcat ccaacacttc cgagaaaagc tctccgcctc ggagccttcc ggggtcatgg
     8041 tatcgctccg atgccatgta tcagctggag cgacgagcca tcttctccaa gcgttggatg
     8101 ctactcacac attctagccg actaaccaaa cccggcgact tcctttcctt taccatctcc
     8161 aatttctcct tctttctaac tcgggaccgc gaaggtagca tcaatggatt tcacaacatt
     8221 tgtcgacatc gcgcataccc agttgtccaa gctcggtctg gggccacctc gatcctcagc
     8281 tgcaaatatc atggctggtc ctacggactg aagggcaacc tatcgaaggc acctcgcttc
     8341 gagactgtat caaacttcga caaaagtcag cacggactcc tcccaatcca tgtacatatt
     8401 gataaagcgg gcttcgtctg ggtgaatcta gaagccgggg acccggaggt caagtgggag
     8461 gatgacttcc aaaagatcga tgagcagccg cggatgcaag actttgactt tgacggggaa
     8521 tacacttttg accattattg ggagatggac gtggaggcga actggaagct tctgattgag
     8581 aactacaatg aatgttatca ctgcgcgacc tcacatccac tgatcaatgg agtgtcggat
     8641 ctccctcggt accgggtcga gcccaaggcg aggtacatgg agcatcatat cttcaacaag
     8701 gacaatattg atgcgcagtt ccgacgatca atcacgtact tttacccgac gacgtcggtc
     8761 acagtcacgt aagtttgtat ccgaaaggga aggtcgatgg tcaattgaca caagcaggga
     8821 caaattcttc tatattcaac gcatgatccc agttagcgcg acaatgagca agatcgaaaa
     8881 cgaagtatat cgacacagag atgccaccga cgaggaattc gccaatatca acgcgtttta
     8941 ccgacaggtc ttagacgaag atcgggacct ctgtgttgga gcgcaagaaa atctgagcgc
     9001 gggggtgttc atcaacggcg aactccaccc ggacaaggaa aaggtattta tgacactgtc
     9061 cagacaggtg taaaattagc aagcgctaat tgtgagcagg gacccatcca ttttcaagac
     9121 catgtcaaga caatggtcat ggagcaccgg cgaaaagaag aggagcaagg cggggaagaa
     9181 atctggccag ctgttcccaa agtgactggg gagatgagga cagggaagct ggcagaggag
     9241 gagaggttct gttctcagct ggaagcggcc agttgcatgg cccgatcaga gcttgcttgg
     9301 taatgtttta tctgaatgtg atgttataaa gtgataagcg ttcggggcat tgcatattag
     9361 agacatttgc attgagcagt cacttcagtc agactgtgtt gatttggaga atgaaaacat
     9421 acccacccaa ctgtcaaggg tgggggagtt ccctcatcta ctccgataac gtaacccatc
     9481 cccttttccc taattggctc tcccactgca gcttcatact tactactatt ttccactcat
     9541 gcgttcgtcg cgtcaatccc gtgctttgtc gccacagctc aataacgttg aaaaagagca
     9601 gctggtcatt atttcatgca ttgctcacta cccggtcagc ttactcctgt catgaggtca
     9661 gagtacgtca gagcctccct ggtctgtcga tcggataccc agtgaggaca tttccttata
     9721 tgattgacga caggtggaca gtttctgaac tacttagcat taacttaact agccattctc
     9781 aattctaccc tgttttatgg gtggcaatga gcatcccaga gcaaactttc caacgttcat
     9841 aaagcagaga cgcatccgca gatggtccct ttccggaagc tggggtagga aaacaggatt
     9901 cggctaaacc ttgcagagag gactgaacgc cctttgactg atatatgttc cataagctca
     9961 gtagtcgcca taagggaatg agagataacc atgaatcaaa atgggactcg actatgttat
    10021 tctgtaagag aggtacctcc tacaagcttt gtttctgcac ctgctaacta taagcgcgca
    10081 agcagtcatt gcacttatac catccctgca gcgtcggcac tgacagtgct gtactatcca
    10141 ttcttcactg cacaagatcg atgcaagata tgcatcctaa ttacggtaca ccaattttac
    10201 cctgcggcaa ggacaacttc agttgatatg accgggaatg acagattgcc atactcgcga
    10261 cgctcccgtg ggattcctac ctcatacggt ccgctatctg gacttatccg ccagacgcag
    10321 tagtcggcct caagatactt gatattccga ttgaagaggt tttctttttc gccatacaga
    10381 catacatcac gagcttgaca tactgtatct tcactaagcc gcttgtgcga cccatgtacc
    10441 ttcggtcaca tctggagaga cgtggaacaa gatatgtggt agcaactgtc attttggcat
    10501 tgatgggtgg tgggacagcg tgcctgctgt tgggacggcg tatgacttac ctaggcctga
    10561 ttcttgtgtg ggcgtgtcct atcctgctat tccagtggta tgtttggtct acgcgtgaat
    10621 ccattgaggt gctcatgcga gaacacagga tgatgtctta cccttttcta tccgaacttc
    10681 cctggaaacc aacaatcacc tcaatctgcc tccccacgct acacctctgg tttgcagatt
    10741 cacgtgctat gggtaccggg acttggagga tcgaggaggg cacaaaattg aactttcgta
    10801 tcggaggtct agaacttgag tcagtcaggc ccaccggtgc attattagac gtcggatcta
    10861 acagtagcag agaagcgctc ttctttctgg tgagcaatat gatggtcgtg ttaggactgg
    10921 ttgggtgtga ctacgcatac gctcttcaag aatacgaatc cctatcacag ccagcgtcag
    10981 acgtctacat tacattaaga aaagcactgt ccttattggc caggccgctt ccaattgacg
    11041 catctctcat atctgcattg tcccaggctg tatatcgtct gcaagagaag agtcagagca
    11101 tgtttctcgg cagcgcatta ttccagggtc agctgcgcat tgatctgata ttcctgtatt
    11161 accccttagt ccaaacgtgc ttcattgttc tgacatgcat aggtactcct tctgccgcgt
    11221 catggatgat ctcattgacg aagccgagga tgaacaggag gccagatttt gggttacaga
    11281 gtgcaggcat ctcctagatt caacccatcg cagtgaacca cattccgacc acttttacac
    11341 tggtaaaaag ggggaggaac atgaaagact acgtcaatct atcagctacc ttcctccctc
    11401 acatctatct aatgactctt ttgatgatct tttaaaaggg tttgagatcg acctcaaatt
    11461 taatccccag agagaagctt tcccgatcca gtcggagtat tgtctagacc aatacgcagg
    11521 atttgtagct ggcactgtcg gtgtactggt cttcgacctt accttattcc attgcggtca
    11581 ttactttatc caggatgtac cgcgattgag gcgagcggcc aaggatatgg ggaaagccat
    11641 gcaatgtatc aatattgcac gtgatatcca tcgcgatgca gcaatcggac gagtatacat
    11701 tcctacaaca tggttgggcg aagtgggttt aactccggga gatgtattac aatgtcctaa
    11761 ctccccagtc acgtatgatc tacaggagag aatgctgcag aaagcagatg aatattatca
    11821 ggtcagccga ggggcgatgg aggagctacc tcggggcgta agagagccat tgcgggcaac
    11881 cgtggcgagc tatatggata ttggactact gctgagggag cggaaaggca caagcctggc
    11941 gcaagcgtcg aagatgaagg tgcctttggt gcgacggcta aaagttggtt ggctggcgat
    12001 gttataactg aactctgtat gttgaattgt gtgctacaca tatttttcac aggtcactgc
    12061 ttcattcagg ccgaatatgt gatttatctc gtcaggcatc agaacgctag tgctgacact
    12121 cttgtcctat tgtcagctcc gtctatcggc tggaatgacc acatctgttc ttgggacctt
    12181 ggcttttgca ccagccggcg cagacaacta ggcccggggg tttcagctaa cttcacagat
    12241 gagatttatc tgacagtctg aagaaatcgc ctcggcgcta ctgtccaccc gtctgacaag
    12301 agcatgtgtg gcgttattca gctctgcaac ggttcggcca cgacttgtat caagagagcg
    12361 tcatcggcaa ggacaaccaa aacctcgtct tttgcttagc cttgtcttcc acaacaactc
    12421 tccggcttta ccgataggtc tagctagaga ttgatacagc cagccactgc aaaaattccg
    12481 cagacaagag ctgaaaaagc gaccctgaga tttccgggat actcacaatc ttttcagtgc
    12541 ccactagaag gttgacctga tatggttcca cgaatataag ggtgctaagc acccaagact
    12601 gggagccttc tgaagaatac ttttcaaaca ccgacgcaga catctctata ctgcgtaagc
    12661 agaataaaat ctaaaatgca ggggaaactg gaacttgttg attttacttg cttctacgag
    12721 ttttgcactt atttactcgg cgctgcaggt gctttgcttg aaagcgatgt cgtaaagaca
    12781 agaccaaaca atacaagggc ttacaaagtg agtgaacatt gctattactc atgtttccag
    12841 aaggctcaca agtgtatagg aagaatggtc ctggaaggac cttgtcttga ctatctggct
    12901 atttaccgcg gatgacttta ccacatttgt catacctgaa acagcattcg ggatatgcgc
    12961 cgctctttcc gggccgcttc tgacggacga taacactccg gacttactct cagtcgttag
    13021 tcggataccc attgtcatgc tctggaactg gctaaacctg tttgtgttta acctggcgaa
    13081 tcaaaggcac ccggactccg tggcagaaga taagatcaac cgaccctgga gaccactacc
    13141 ggcaggtcgg atcagcatcc tgcagactcg ccggttgctt ctacttgcaa ttccaatggt
    13201 gctcgcatcc agcgtgtatc taggtgcatg ggaggagact gctctccttt acacccttaa
    13261 ctgggtatac aatgacctca gcggtggtga cgacgggttc attctacgga atgtccttct
    13321 tgccctcgcg ttcagccaat acaacaaggg atcattacgt gttgcgaccg gaactggatt
    13381 cgatatactc cctagagcat ggcggtggat ctgggtcacc agtgccgtga tcggcacgac
    13441 gatgcatatt caagatatca aggacgtgga aggagaccgt gccaagaacc gccggacaat
    13501 gcccattgtg atgggtgacg ggccggcccg gtggtccgtt gcagttcctg ttgcaatttg
    13561 gtccgttgtt tgtcctgcgt tttgggagct agacgttgcc aggtacgttc tcccggttgc
    13621 ggtgggaatg actattgctg ggaggatctt gttattgcgg gaaaaggctg ctgataaacg
    13681 cacgtggaaa atgtggacgg cgtggactgc agttatttgg gtgcttcctt tgttcaagaa
    13741 tgctagtgtt tttgtcaggt ttggtaagaa gcttggggtg gtgtgaggca ttgctcaagc
    13801 caagtgagcg agaatttact tcgcttgcag gctgttgtgg tcatgtcact taagtaacaa
    13861 tgtgacatga caagtagcta tatcgcacgg gagagttgac agatccagta ttttagaaat
    13921 cagatggtct tctgaaattt cttccagttt actagatctt agatcattca agtgccaaga
    13981 actacaagca gtagcatcat tggtctagtg gtagaattca tcgttgccat cgatgaggcc
    14041 cgtgttcgat tcacggatga tgcaagcgaa tttctttttg cttttacccg atagcgtcca
    14101 tagtggggtt gttcctgact actattttct tctgcggaaa acccattttt tacagcgtcg
    14161 cggattgaga tgggcagcaa tggacgatgc agagaacgac aaatctaatt tgttttctac
    14221 catcgatgaa aagccaatct cttaaacaga ggatccacca cgaaatatat tactaatcat
    14281 tctggtcgag gccacttcag gaatactaat tggacacgat tgttgtgtta aatcagatat
    14341 atatatctgc tccgttcagg tagaggtaat tttctctatg aagctgctga gacgagcaac
    14401 aaaattacta ctgcccctac tatcatcatt tcaacctttc aatacttggc gtaggcatcg
    14461 tattactaga ttgtgtagat ggaatttcca gtctccagca agacgtaaac atgctcgttc
    14521 catatactat actaccagct tacggacagt aacaggacac aaccaaccta cccaaaacat
    14581 tgaatataac ttcataatct attcgtcaaa gcatgctccc atctctatag tagcttacag
    14641 tctactcccc atattaacat gcaccgcctt aacctgcgag tacgcctcca gtcccgcctc
    14701 tcccagctcg cgcccaatac cactctgctt cacgcctccg aaagggaccc tgggatcgca
    14761 atcctggcta ctattaatcc agaccatacc ggcctcgata tccgccgcga cgcgatgcgc
    14821 cctctccaga tcggtcgtga agaccgccgc gcccagacca tacgtggtat cgttggcgcg
    14881 acgcaccgat tcctcctccg agtcgaatgg caggatgacc accacgggac cgaatacttc
    14941 ttcctggcag atgcgcatgt catccgtcac gtcagtgaac actgtcggct cgacaaagta
    15001 gcccttcgcg ttcttttcgt ccttgggagt ataggccttg ccgccggtaa ctagcgtagc
    15061 gccctccttt ttggctgttt cgatgtacga tagaacgcgc tcgtactgtg cccgggtaac
    15121 ttgcggcccc tgataggtat tttcgtccca ctggtcgccg atcttggaag tcgtctcgat
    15181 ctccttcttg aacttctcca agaaggaggc gagaatacta cgatgaacga agatcctcga
    15241 cgtagcagtg cagatctcgc ccttgttgga catgattccg aaatgcgacc acttaaccgc
    15301 ctgttcaaga tccgcatccg ggaatacgat caagggcgac tttccgcccg tctcaagggt
    15361 gatattcttc aatgtgccgg cagccatctt tatgatttct cgagcggtgg cagtagagcc
    15421 tgtgaaggca atcttatcga cgagcgggtg ctgaaccagc gcagcgccgg cttcttttcc
    15481 gtagccattg atgacattga ccactccggg tgggaatccg gctttcttga tgagtgttgc
    15541 gaggacaagg atgctgaggg gagtttgttc agcggccttg ataacgacgg tgtttccgca
    15601 ggcgagcgcg ggaccaagct tccacgtcgc catcgagagc gggtagttcc atgggatgat
    15661 ctgtccgacg acgccgatgg gctggcggat ggtgtatgcg aacttttgag gagtggtgct
    15721 gatcgtctgt ccaaaggtct tatcggccca gccgctgtag tagcggatgg tggtgatggc
    15781 ttcggtgagg tcctcggtca gggcgacgtg gtagggtttt cctgttggcc aagtcagtgt
    15841 ctgcatatcg gtgaggatgg tgagtatacg aaccgttatc ccaagcatcg atggcagcaa
    15901 atagtgcccg gttttcttcc atcaaatcgg ccagacgacc catcagctgt ccgcgctcgg
    15961 tggcagggag gagcttccat gaagggtgcg acagggccgc tttggcagct tggacggcgg
    16021 cgtcgacatc ctctgctgtt gcggcgtgga cagtggcgat gggcttgtcg gtactgtgaa
    16081 gattagcatg gaggcgtaga aggagacaag aattcgtagg tcttacgccg gatctaaaga
    16141 cacgatggtc tggccactgg acgaaggacg gaactcattg ttaatgaaca ggccggtcgg
    16201 ctgctggtac tgccgaccat tgggggtggt gatgtcgaca aagagggagt ctgccatgtt
    16261 ctcttcttac tcttcttcga aataacagat aacagtagta gcagaagaca gtgataatca
    16321 gcgcgagaca gagtgtcctg tcttgatata tgctacttgg ctagaacttc ctgttccgga
    16381 tgtgggatgt gcctccgcgc agaccacttg gcaattgacg tttgtcacta gtcagcaaat
    16441 cccccgtccg ataaggcgat aacaaggata agatcgtccg attacccctc acttctttga
    16501 tgtcgagacg caatcgatag tttggcgccg gtggatgcgc taatgcctcc ccactgcatg
    16561 ccggaactgc ctgccggtgg gtaatcccgc atcgccagaa tgggcaggtg gttccggcat
    16621 gtcttgttac ccctctgaga tcctatccag acagttaggg cttcgttcat actgccagaa
    16681 caatcatcaa aagtattgta tagacatgaa ggagggattg agagggaagg cagtcccgtc
    16741 gccgcatgaa ataaaaatgc cctcgagact cgactcacga gtccttcaat aattgttctt
    16801 tcagtccttc acgtcattct tccttgcctc aactatacca atcaacaact acaaccaaca
    16861 tgactgtcac acagcaaacc cccgcccttc acggcatcat ggttgccctg attaccccct
    16921 tcacagacga taagacccag atcgacgcag caagactcaa atcccacatc gaccacctga
    16981 tcggcgccgg cgtgcatggc ctcgtgccgg gcggcagcac aggcgaattc accaccatga
    17041 cccgcgaaga acgcaagcaa ctgactgagc tctgcgtcga gtatgcagct ggccgtgtcc
    17101 ctgtcgtagc gggcacaggc agtacctcca ctgaggaggc agtggatctg gcacgtcatg
    17161 ccgcgcaggc cggtgcggcc gctgtcatgg tcgtgccgcc attctacgac cccttgaacg
    17221 tggagcaatt gaccgagctc atgtccgaaa tccacgaagc cagtcaactg cccattgtct
    17281 actacaatat cccctctgcc agcgggttga ccctcacacc gcagcagatc gcggatctga
    17341 gcaaggtcgg cgtcaagtac ctcaaagaca catctggaaa tgctccagcc tacacggaat
    17401 tggtgttcgg gttgtcagat cagatcaccg ccttcaatgg ctgggatacc cttacgttct
    17461 atggactggc ggctggatcg ccgggagcag tttggggtgc tgccaacatc atcccagagt
    17521 tggcggtgga gctttggaat gccgtttcgg ttgaaggaga cctcaagaag ggtcgggaac
    17581 tgtgggccaa ggcatggccg atctgcaagt tccttgagtc gcacaattac gctgcagcgg
    17641 tcaagacagg cgtggagctg aggggacagg ccactggtgg gttgcggaag ccattcgccc
    17701 tcttgaagga tgatctccag agcgagctgg cccagttgat ggtgaatgcg aatgttaatg
    17761 ttgtcaagcg ttcgtcatga aatagtcgcc attggatata gaaaaataaa tttatgagga
    17821 catgtcatcg tatctcttgt agcgccttgt aacagacccc ggcggtcatc atgctagaat
    17881 gggccatatt tgcttgcttt tgacaacatc aagccaggtc ggaaaagtct ctcctctgct
    17941 tcgtgtaaag tgcgcatctt gtttgtccca tacctggttc atgacgtccc ggacagtatg
    18001 ataggcagaa aatccacatc gtgcttcgcc tttgtctagc agcagtgtga tcgattgccg
    18061 cctttcgggc gtcgtcgcct cgcacccagc aatgaaaaga ggccagactg tacctgggcc
    18121 ggtgtgatct gcttccacta gtgctacatc aaactcgttc aacgatgaga tcaccttgtc
    18181 cacctggctc tccaaaatag ccgggtggac ctgacggatg cgtctataga agaagataac
    18241 cagcgcagaa tttaaagcct gtaaaaggca tccatgtgac ttggccaata tgttggtcga
    18301 atcgcatatg ttgtcctctg ttctcctgga cgcgaatgtg cacaccatgc tctcgagacg
    18361 agcactgcgc cgatgcaatg cttcccatgc ttcgagactt gcattattcc cttgacgcat
    18421 ttcgcgcgca actcgaaagg tttccattac attggccagg cgtgttgttt gagataccaa
    18481 gctgagccac gtctccgata ccccgtaaat ctggctatat agtgtggcag gatacttgcg
    18541 cgaatcctgc aaatgaatat catataggcc aacgtcgtcc tccttcggct catcaatgtc
    18601 caggtcgcta tcggacgggc gccgatcgag gcgcaaaaag tcgtccaagc gtgatgttcg
    18661 gtacccagct gcttgagtat tttcgacttt ctggtaccga aaccgatatt tgagagcctc
    18721 cataaaggca tccgagggcg tgtagttgtg caaagcgtag gtgctctcac ctacaattcg
    18781 tagccacgta tatgtgtggt gtaggaggcg tgctttttga gaaatccgtt gtttaggcaa
    18841 ccctcggagg cggagcagcc gctcagcatc gatcatatag catcttgcat cctgctgctg
    18901 actacttagg atctgtttcc ctcagtaagc tacctcgaac aaagttagac aggaatcata
    18961 cagcaaattc agtcaaggcg caaattgcca tgagctggtc cttgtatttg gccttctttg
    19021 gctcttgtgt ttcatgcttc agagacatct gcatgtgatc ttttgccaga tggtaagcat
    19081 attccgctac cggcttccat cgttctgttg agtccgaggt cctcatggaa gggtttaccg
    19141 ttaaatggag ggctgaacag gccaagaggc agtacagatt ggctaatcga gcatgagtga
    19201 tgttttgcga ccccagaaaa gtgatatcgc tatatgttac aacagcagat ggcacattga
    19261 gtatcttcca aggtgacttc tggtctagag gaacggccat catacgcgaa atgacatgat
    19321 cctggaaatg tcgtagtagg taatgagcat ctgctagtac atcaggtgga ttgctatcaa
    19381 ccggcggcac catcttggag gcattgtctt gcccagggac acaatggtag agagctgctg
    19441 tatcatccat cagactagga gcttcgccaa ggagattatg ttccagcata ggggcttgtg
    19501 tccccaaatc caggggcaac caatcgccca ggtcgaatgt gccagatagt gtagcactct
    19561 gcaactgagg atccaagcta agaatatctg accactgcag caggtcattc atgtaggcga
    19621 tcgactcttg cgacagagct ggactgactc cggaagcgcc ttcagccagg gtatcccccg
    19681 acggtagaat cacatcattt gcgaccgtag tctcgtcagt gggatgagcc cgacttgcag
    19741 atttgggttc ggtaaggcta aagtccagca cagcaaatgg tccaactaca atatcgccct
    19801 gtgagggcct ctccgtatcc cgggatcttg tttcgatctc agccaatgag gcatcaatag
    19861 agcccgacac caagtctgca ctcaatgcat cgctcatgga gactctcgac ttttctaatg
    19921 tctatacatt agctttacca ttttgaagcc ggtgatcaga tcatcgatgt atgagagagg
    19981 gtgatcaacc tgtgtagaga tggcgtcgag gcccctgctt ctccggatca tttgccttct
    20041 tagctgttgt ccccgaagaa ggctgggact tccgatcgga catccatcgg atctcatcaa
    20101 cgaacccctc acataccaca cctgttgccc gacacatctg gcaggtaggc ctcttttggt
    20161 cgcatttggc atgacgcctt cgacacgttc tgcaggctcc cagggcatga ctgcgacgag
    20221 tccggcggcc tgattgcttg gaggaagtca tgtcactcag agcagggcat tatcaacgaa
    20281 aacggaaaga aagggtaatc gaacagaatc tggggtatga gtcgggtggc cctggagctg
    20341 gaaggtgaag caattattag caggtccccc agaaaggagg gtgtggcccg accgggcagg
    20401 caggcggttc cggcggggcg gaatctcctt cctgttcgga ccagaacagc gtcggaagga
    20461 cctgctctcc cgggtttagc ctttcagtat cttggaagct tgatgacacc gagttgtatg
    20521 ggcgataact agatatgttg acttcggtgg gaatggacaa ttgtattgta agtgaattta
    20581 ttcaggtatt ctaataactc caagatagat ctatttcagt cccagtctct gggcctcggc
    20641 aagaacagtg tgtgggattt cctcttccaa cgtccttcct tcggggaccc atttcaggta
    20701 cttggccgct cgctgagcca cctgctgggc attggttccc cacaacactc cgccatgagg
    20761 cgtgagtgaa tcggcctctt catggctgat ctcagttacc gactcggact cagcaaggcc
    20821 gagctttttc acttcttgcg ccactcgtgc tgagatggaa ccgaatgact gtactctcgt
    20881 tagaatgtac cttgttctgt gcttaggtcg gagcatgtaa gaacttacga tagccctgga
    20941 accggggaaa tacaacccgt tctcattcca caatttccct tcctcacttt gcaaagcctt
    21001 ctcggccagc ttcacaaaga tgttgctgac atccgagatg tgcacattac tccatgtggc
    21061 ttctcctctg cccacctgaa ccccgccccg tcgctgcatg gtcactcttg ccagctccgg
    21121 gatttgtatg ctccgctggt taatcggtcc cctaccgcga ccgtaaatga tcgggggaaa
    21181 tattaacgcg gttttaggac gagaggaagt atggggaagg ctgaggacta gattgtcaac
    21241 cacacgcttg gcagagtact gtcgaatgag ctcccgcagc tcatcagcac catcgacatc
    21301 gctgtaaatc ttgttggagg gccctccaaa ggcgctggct acaatgtcag gaatggaaag
    21361 gacgcttgcg cctgatatct gaagccagtg acctgcttga ttcatgagaa gtgtgagggg
    21421 acggaacgaa tgggaggtaa ttacccggct ttggtctttc cggtgcagtc aatccacgcg
    21481 cgatggcttc ggcgctcttt acgtgatttg agcttgcggt gtctgagaaa ggaggccaat
    21541 attagcagaa ggcagaaaga attgaagcaa gaacactcac ggatgacgat atctgcttct
    21601 cgtgcctgtt gttccaaagt ggaagaggcg tccaaatctc ccaggactac ttgtacatca
    21661 gggtacgctt gagagagttt ctgagccttc gcctcgtctc tcagcaagac tgtatactgg
    21721 caagttggaa gggccgattt cagcgcatgg aggacatccc ctccaatata acctgaggct
    21781 cctgtactat gatttctgtt agtagcaagg aagaggacga atccctggat gtacctacag
    21841 aaagattttc gccattgtga ctggaatgtt catatgtgac tctagggagt gcaaggcaag
    21901 aaaaaaggat tttagtcaag gcgtgtagga acagctaaat tcaaagtaaa atgatgtgat
    21961 gaggggttgt tgtttctgag gggcagatat cgatgtggta ggtgattccg aggaaacacc
    22021 atcaccccag agtgggaatc cggggatagc tgataaggcc ctccaatgca cagaattgcc
    22081 aattggcata gagcagctga cgctttgtct gtccgtgcct tatgacagtg tcatgctagg
    22141 caggtatctg agattggttg tcttttgctt tcccctttcg gcgtcaagga atagctgcgg
    22201 tcgcaggaca acagaacaat caggaaagtc gatgacaccg agctatgata tatagtatca
    22261 agttaatgcc caattaggga cacgagcatt aatattgaac cttggaactt gcttctcctt
    22321 gattttattc ttgagcattc tgcactgaaa ccattgtcgg catggctcat cgcggcgaaa
    22381 cattccacaa agatgtcaac tgtatcgctg atcttaaggc gatggggagc aagaagctcc
    22441 caaagatggt cagaggtagg gcaatcgagc gaaaactaat atgcacttct gatgactaac
    22501 gctggtgatt attagattac tacaatgaag gtgccatgga cctgataacg tatgcgcgaa
    22561 tactcaaggc gaccaattta gaacaatcac taacggcaca gtctacgcga caacgaagcc
    22621 gcatttgacc gatacagaat tcgcccacgg gtcctggtaa atgtggccaa tatcgacacc
    22681 agtacggaga tacttgggac caaggtagca cacgtatcag tctaacagct cacagaatcg
    22741 ccgctgatac acttccttaa atacacaggt atcccttcct ttcggcttca gcccagcagc
    22801 cgcacacaaa ctcgcccatc ctgaaggaga gctcgcaact tctcgggccg cggcgaaatt
    22861 tggtatttgt atgggcctct cctcatactc gaccacccca ttggaagacg tcgccagtca
    22921 aggcggcggg aatccctatg caatgcagat gtgcgtgctg aaggatcggt ccatcacatt
    22981 acagttgctg gaacgagcag aaaaggcggg ctacaaggcg ttgttcttgt cggtggatgt
    23041 tcctgtcctc gggaagcggt tgaacgagta tcgcaacaat taccagctac ccgaagatat
    23101 gcaatggccc aatattctca gcgatgggaa agatacgtcc gatcgaacag attatggtta
    23161 gtccctaaca acatgggctc attcattgga cggcccgctg atatttacca gatgctagtc
    23221 ttgactggga tagtgcgatc ccctggctaa ggaaacatac taagcttcag atctggctaa
    23281 agggcagtaa gtagaagttt ctggatagga agcagacccg gattggctaa tgtgggcagt
    23341 ctacacaccc gaggatgtcg aactcgccat acaacacaag gttgacgggg taattgtttc
    23401 caaccacggt ggtcgccaac tcgacggtgc cccggccacc ttggatgcac tccgcgactg
    23461 cgcgcctgta gcaaaggggc gtatcccgat tgccatcgat ggtggaatcc gtcgaggctc
    23521 agacatattc aaggcgctag ctctgggggc agactactgt ttcatgggac ggattccgat
    23581 ttggggactt gcggtatgtg gagccaggaa ctgctgtgaa tattgtaatg actcgtttta
    23641 gtatgatggc caacaaggag tggagctggc tattcggata ttgcgccagg agttgatgat
    23701 cacaatggct ctggctgggt aagttgctgc ggatgatgac tggaaagtgc tatgctaacc
    23761 gttccagatg tcggtcgatt tctgaa
//
