LOCUS       NKJJ01000006.1         19590 bp    DNA     linear   PLN 19-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   NKJJ01000006
VERSION     NKJJ01000006.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 06:54:43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 436341
            Orig. end    :: 455931
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..19590
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[445683:446010](-),
                     [445276:445629](-), [444893:445221](-)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(join(8553..8880,8936..9288,9343..9669))
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..19590
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..19590
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            join(1..8,67..340,405..481,759..861,909..1153,1208..1355,
                     1409..2014)
                     /locus_tag="CAN33_10065"
                     /product="GXWXG protein family protein"
     gene            1..2014
                     /locus_tag="CAN33_10065"
     CDS             join(1..8,67..340,405..481,759..861,909..1153,1208..1355,
                     1409..2014)
                     /NRPS_PKS="Domain: NAD_binding_4 (136-362). E-value:
                     1.2e-13. Score: 42.4. Matches aSDomain:
                     nrpspksdomains_CAN33_10065_NAD_binding_4.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR025568"
                     /db_xref="InterPro:IPR025951"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF01370"
                     /db_xref="PFAM:PF07993"
                     /db_xref="PFAM:PF13460"
                     /db_xref="PFAM:PF14231"
                     /db_xref="PFAM:PF14232"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 97;
                     E-value: 2.4e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_10065"
                     /note="GO_function: GO:0003824 - catalytic activity
                     [Evidence IEA]; GO_function: GO:0050662 - coenzyme binding
                     [Evidence IEA]"
                     /product="GXWXG protein family protein"
                     /protein_id="ncbi_CAN33_10065-T1"
                     /sec_met_domain="NAD_binding_4 (E-value: 5.7e-13, bitscore:
                     42.4, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTSAAEQYRTLVQTKGKVAPATLSNLFDQLPPLKPEQLLGSWNGG
                     FFDTGHSVGPTLQRIGWIGKDFNTLDDVDPVIVLREGRRASWGQWGHATVREMVFRGVL
                     STVMIYDDRPIFDHFRYNIENMSSSGHGQHVLLTGANGFVASHILSILLDRGYTVTATV
                     RSQAKADEVVKAHPDWKGKIEFAIVSDFTSQKPFNTLFEENKIAFDYVIHTASPLKFDI
                     KDIQKEMIEPAVKGTTQILESAHQHGGSALKRFILLGSAVSVLDSFEDMSREGRPYTEK
                     SWNPVTAQQAIERNDTVLGYNVSKTQAERKAWEFMQANNPNFDLTVINPDIITGPMIHP
                     ITGKGSINETNHFAIASFIDGTNSKVEDVRFPFYHFVDVRDVARSHVDALSNPAAGGQR
                     ILLISGLITPQLVVNIIRKHFSELREKVPVGIPDRVLPEGVHPTGWDMRVSLDVLSKGK
                     GSQWQYIGLEESVKDAVQSMLQHNVLPV"
     aSDomain        join(808..861,909..1153,1208..1355,1409..1639)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_10065_NAD_binding_4.1"
                     /evalue="1.20E-13"
                     /label="CAN33_10065_NAD_binding_4.1"
                     /locus_tag="CAN33_10065"
                     /score="42.4"
                     /tool="antismash"
                     /translation="LTGANGFVASHILSILLDRGYTVTATVRSQAKADEVVKAHPDWKG
                     KIEFAIVSDFTSQKPFNTLFEENKIAFDYVIHTASPLKFDIKDIQKEMIEPAVKGTTQI
                     LESAHQHGGSALKRFILLGSAVSVLDSFEDMSREGRPYTEKSWNPVTAQQAIERNDTVL
                     GYNVSKTQAERKAWEFMQANNPNFDLTVINPDIITGPMIHPITGKGSINETNHFAIASF
                     IDGTN"
     mRNA            complement(2186..3274)
                     /locus_tag="CAN33_10070"
                     /product="2-dehydropantoate 2-reductase family protein"
     gene            complement(2186..3274)
                     /locus_tag="CAN33_10070"
     CDS             complement(2186..3274)
                     /codon_start=1
                     /db_xref="InterPro:IPR003710"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR013328"
                     /db_xref="InterPro:IPR013332"
                     /db_xref="InterPro:IPR013752"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF02558"
                     /db_xref="PFAM:PF08546"
                     /locus_tag="CAN33_10070"
                     /note="GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]; GO_function: GO:0008677 - 2-dehydropantoate
                     2-reductase activity [Evidence IEA]; GO_process: GO:0055114
                     - oxidation-reduction process [Evidence IEA]; GO_process:
                     GO:0015940 - pantothenate biosynthetic process [Evidence
                     IEA]"
                     /product="2-dehydropantoate 2-reductase family protein"
                     /protein_id="ncbi_CAN33_10070-T1"
                     /transl_table=1
                     /translation="MPLQSHTTRPTIHVLGLGSIGTFTAHGLKDIPNPPAVTLLLHRES
                     LYQEYIRNNRQITLKPVTGDTMHHSDYNLEIYKQGAWHTPADSPADHQIDNLVVTVKAT
                     QTVSALRALRSRLSRASTVLFLQNGCGMIDEVNEHLFPDPATRPNYLAGVISHGVTLAS
                     PFNAIHTGASAISLGLVPRPHSQSSPNTRETGNQLQNRGGSEYMLHNMPVSPRLSAKSY
                     SFSDVFQIQLEKLAVNAFCNPVCALHDSKNSILFEFPKLRRAILTEISSIVLRLPELRG
                     VDGVEQRFAVDRLEETVNGILERTRETTCSMVVDLRNRRETEIHFINGYWVRRGKEVGV
                     STAINEELMDKVLRRSAALRSE"
     mRNA            complement(3995..5578)
                     /locus_tag="CAN33_10075"
                     /product="hypothetical protein"
     gene            complement(3995..5578)
                     /locus_tag="CAN33_10075"
     CDS             complement(3995..5578)
                     /codon_start=1
                     /db_xref="InterPro:IPR013087"
                     /locus_tag="CAN33_10075"
                     /note="EggNog:ENOG41; GO_function: GO:0003676 - nucleic
                     acid binding [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CAN33_10075-T1"
                     /transl_table=1
                     /translation="MECGEEFIDPSLLCHSTLDGHDLDSRHFNLSNPQPYDLNLQQVPA
                     VLPNAQQRAVPSELFEDATTNNTTAPRGQLPRRRSRYLTRHSGTQAYSVMIPKASSFSP
                     MERWRNSPPEEEGCLIPDIIDALRDNPSQGVQTNLQNPGDDYSAFHGYRRAASITSGES
                     SASSRSTQKSGRSSSSAQNPLAVQGRHGNIRAGKTTRRKTKITSTTAQRRYCCTFCCDR
                     FKSKYDWARHEKSLHVTLEAWHCAPYGTTIMSSNEPSMTRCAFCGLTNPDSDHLEEHAA
                     TACEDESSSRRSFRRKDHLVQHLRLVHNVDSPPQLDSWRIGQSAITSRCGFCSQALMTW
                     KERVDHLAEHFRTGSTMAEWRGDHDFPPDFAALVANALPPYLIGSESQSMIPFSATNCD
                     VEDHLAQIYSRANWDAKDQKEASTITAPSAPSVALPLRALAPGVAPERLSSFTQVLTLH
                     LSRFAQEQMKKGVIPSDEMFQQESRRVLYDSDDSWNQTIADNPEWLATFKDLHFDKEKG
                     VHDSGENFAS"
     mRNA            complement(join(6589..6967,7056..7125,7168..7361,
                     7431..7585,7636..7809))
                     /locus_tag="CAN33_10080"
                     /product="Polyprenyl synthetase family protein"
     gene            complement(6589..7809)
                     /locus_tag="CAN33_10080"
     CDS             complement(join(6589..6967,7056..7125,7168..7361,
                     7431..7585,7636..7809))
                     /codon_start=1
                     /db_xref="InterPro:IPR000092"
                     /db_xref="InterPro:IPR008949"
                     /db_xref="InterPro:IPR033749"
                     /db_xref="PFAM:PF00348"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 190.7; E-value:
                     5.1e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_10080"
                     /note="GO_process: GO:0008299 - isoprenoid biosynthetic
                     process [Evidence IEA]"
                     /product="Polyprenyl synthetase family protein"
                     /protein_id="ncbi_CAN33_10080-T1"
                     /transl_table=1
                     /translation="MLGFPMFSPETPDAWKMNTPYFPFVSSGVFSASIPSSPTNIEAAS
                     TSQSETSFLDKEKIVRGPLDYLLKSPGKDIRRKFIHAFNEWLRIPEEKLNIITEIVGLL
                     HTASLLIDDIQDNSKLRRGLPVAHSIFGIAQTINSANYAYFLAQERLRELNHPEAYEIY
                     TEELLRLHRGQEEDYIEMIANKTGGLFRLAIKLMHDVIELADLLGVIFQIRDDYQNLQS
                     GLYTKNKGFCEDLTEGKFSFLIIHSIHSNPNNHHLLNILRQRSEDDSVKKYAVEYIDST
                     GSFEYCRERLASLLEEADHMVKELESQVGHSKGIYEILSFLS"
     mRNA            complement(join(8553..8880,8936..9288,9343..9669))
                     /locus_tag="CAN33_10085"
                     /product="Polyprenyl synthetase family protein"
     gene            complement(8553..9669)
                     /locus_tag="CAN33_10085"
     CDS             complement(join(8553..8880,8936..9288,9343..9669))
                     /codon_start=1
                     /db_xref="InterPro:IPR000092"
                     /db_xref="InterPro:IPR008949"
                     /db_xref="PFAM:PF00348"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: fung_ggpps2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 89.2; E-value:
                     4e-27)"
                     /gene_kind="biosynthetic"
                     /locus_tag="CAN33_10085"
                     /note="GO_process: GO:0008299 - isoprenoid biosynthetic
                     process [Evidence IEA]"
                     /product="Polyprenyl synthetase family protein"
                     /protein_id="ncbi_CAN33_10085-T1"
                     /sec_met_domain="fung_ggpps2 (E-value: 2.1e-115, bitscore:
                     377.9, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MEPLQHHLPQTSLAFLALLAVPITALVWDRILNPLPTTKRAWLVG
                     KKQPSRITSLECPYSYIRQIYGKHHWAPFVDKLAPSLKLEDPPKYQLVLEIMDGIHLCL
                     ILVDDISDGSNFRKGHPAAHKIYGPSETANRAYYRVTQLLNRTVHEFPRLAPFLMQCLE
                     EILEGQDMSLVWRRDGLASFPVGPKERDAAYRQMASLKTGALFRLLGQLVLENKSMDAT
                     MTTVAWCSQLQNDCKNVYSTDYAKAKGALAEDLRNGELSFPIVVALDAPEGHLIARALE
                     YGSPHNIRNALRVIQREDVRSACLWDLKKSSASVQDWLEVWGRKEKMDVKSVKP"
     mRNA            complement(join(11205..12588,12647..13089,13170..13238))
                     /locus_tag="CAN33_10090"
                     /product="hypothetical protein"
     gene            complement(11205..13238)
                     /locus_tag="CAN33_10090"
     CDS             complement(join(11205..12588,12647..13089,13170..13238))
                     /codon_start=1
                     /locus_tag="CAN33_10090"
                     /note="SECRETED:SignalP(1-21); EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CAN33_10090-T1"
                     /transl_table=1
                     /translation="MGHLLMRGWILASLLMQTSIAMTLKVLAQSQAMHTQFFVVCSFFE
                     GSNSYSINHRGTLVECSPLTLYLACKGIANSQFKAGTQSFSSSPPALDLCIPAFTSAKP
                     VFGFVQSNSELFTPCPQTIWNHIQRSSRANPCWGRISSVEHFHILVSCNIRRVFHTAVN
                     YVGGPLYSTTLVTTETIVVSTTVCPVTEAARATRTDSASPTATDTAVNNGHGSGGAELT
                     TSTVFSTRTATITACPSSVTNCPLRSKTTYVTTETLVVSTTVCPVADITGSSGAVIATQ
                     SASHPSASVAVGDNWSSMGGFDITTSTILSTRVITVTACPSSVTNCPMRSKTTYASTET
                     LVVATTVYPVPKVSNTKAKTPLPSVTRASEEGPSLTTSTILSTRIATVASCTGDDCRSS
                     SSDSYVTTETLVVGTTVYTVYPEYVSVPTEGVDAMAAPTTAATLLQTANSAGSSPKVVS
                     SGSQPTSASETSTQGTGSSAGSSAESSEGSDAGSAADSSAVSGAGSGAAADTTYTTTII
                     VESCSNDGTCTEYGSTITMAQTSNLAQPTVPPSPYSYTSYLGSGLGWNHSTPVSSAHVW
                     PQSSHQAGMSTAMVTSTRSASAVNALYTGSASAGSQWSMLQVVGMAVAILTAVLV"
     mRNA            13723..14898
                     /locus_tag="CAN33_10095"
                     /product="hypothetical protein"
     gene            13723..14898
                     /locus_tag="CAN33_10095"
     CDS             13723..14898
                     /codon_start=1
                     /locus_tag="CAN33_10095"
                     /note="SECRETED:SignalP(1-19); EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CAN33_10095-T1"
                     /transl_table=1
                     /translation="MSIQGFIVAAGFLLGRVAAITPAASSPVASSQAYVPSVSCRTQLG
                     TNSVALVPTTTITRTIHDPTPVVVFSTTQDTVTVTPDASTVTVTDYETTTAISTADTVT
                     DTFSTTSTEYDTATVTITPAAVTAIVSVTISTTSTSTSTIASSSGFSPIVETLPTATAA
                     KRSLIEQDDCSSWLDDYQYPQEVECHQKILVKTTTVSTVTQSPATATAVTPTSTVTVTN
                     TITSTSVVAPSDVSTTLSYSTTSTITETTTAAAETTTVTSTTSAVAAVATTTFYEACGS
                     SNIAGDPLSSGFGSFAGQYMYLVTFTNVPGESLTVGDTSSAYDCCVSCMESSTCAMSYY
                     NAVTSSISYCYLIHTTTCSQSSVYAKASVHDASTTMQMSNGNCGRVVGVQG"
     mRNA            join(18926..19151,19202..19391,19509..19590)
                     /locus_tag="CAN33_10100"
                     /product="Ribonuclease III domain family protein"
     gene            18926..19590
                     /locus_tag="CAN33_10100"
     CDS             join(18926..19151,19202..19391,19509..19590)
                     /codon_start=1
                     /db_xref="InterPro:IPR000999"
                     /db_xref="InterPro:IPR036389"
                     /db_xref="PFAM:PF00636"
                     /locus_tag="CAN33_10100"
                     /note="GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA]; GO_process: GO:0006396 - RNA processing
                     [Evidence IEA]"
                     /product="Ribonuclease III domain family protein"
                     /protein_id="ncbi_CAN33_10100-T1"
                     /transl_table=1
                     /translation="MPSFSALAERAQALQNLIGYIFNDPKRAMEALVAAGVYMPGLINR
                     TDGHKQLALVGDAVLRMVLALDGYEARKGREFTNNILSTKAGNTYIAQAGRNLGLDKLV
                     IVNPAQAGMVSDKVMASAVEAIIGAVFMDSDGSVEAYKGPSASVPDSCYEEAPLATQDG
                     GT"
ORIGIN
        1 atgacatcgt aaggaacact cagccgaaca agagggagac aaaatattga ctcagctacc
       61 atcaagtgcg gcagagcaat accgcactct cgtgcaaacc aaggggaagg ttgctcccgc
      121 aacgctcagc aatctctttg accaactgcc tcctctaaag cccgaacaac tcttgggcag
      181 ctggaacggc gggtttttcg acacgggaca ctctgttggt ccaacgcttc aacgcatcgg
      241 ctggattggc aaggacttta acaccttgga tgatgtcgac cccgttattg tccttcgcga
      301 aggaaggaga gctagctggg ggcagtgggg gcacgcaacg gtatgcaagg acattatgcc
      361 tgtcatcgca tggaagtcca aattcagcta atgttgcgta ttaggtccgg gaaatggtgt
      421 ttcggggtgt gctgtcaact gtaatgatct atgacgacag accaattttt gaccatttcc
      481 ggtatgtgga tgacaacttg gtggcggggg tgatggaggg aaaggctgtt gagggagggg
      541 acttttactt ttacttgacg cgatagatta taaatcgagg ttaaggttca gatcccgttc
      601 agatatgacg tttgcgtaca cgtacctctt acatggagta tctcgtaacc tttaagtggc
      661 gtgacatcgg ctctcaagaa attaaatcgg actttgcagt ctccaagagg atttcttgat
      721 tgacaggccc agaggccttt tgacacgacc atctatagtt acaacattga gaacatgtca
      781 tcgtcaggac acggccagca tgttctttta accggggcaa acggttttgt cgcatcgcat
      841 atcctctcta tcttgctgga tgtaggtgac tactctctaa cgagacgtgc aggatctgac
      901 aggctcagcg tggctacacg gtgaccgcga cagtgcgatc tcaagcaaaa gcggacgaag
      961 tggttaaggc tcaccctgat tggaaaggga agattgaatt tgcgatcgtg tcggatttca
     1021 cctcccaaaa accgtttaac accttgttcg aagagaacaa aattgccttc gattatgtca
     1081 ttcatacggc atccccattg aagtttgaca ttaaggatat ccagaaagaa atgattgaac
     1141 cggctgtcaa ggggtaagcc aatagtgtct tcgcaaccgt gttataacca ctaaaataca
     1201 cctccagcac gactcaaatt ctggaaagcg ctcaccaaca cggtggaagc gcgctcaaac
     1261 gcttcatcct tttaggcagc gcggtctcag tcctggattc cttcgaagac atgagtcgag
     1321 aaggacgccc atacaccgag aaaagttgga atccagttcg tcgttcaaga acctgaaacc
     1381 ggcaagacac acgctaatgg aagtctaggt aactgcgcaa caggcaatcg agcgtaatga
     1441 cacagtgctg ggctataacg tttctaagac ccaagccgag cgcaaagcct gggaatttat
     1501 gcaggcaaat aatcccaact ttgacctcac agttattaat cccgatatta tcactggacc
     1561 catgatccat ccaatcaccg ggaaggggtc gatcaatgaa actaatcatt ttgccattgc
     1621 gagcttcatc gacgggacta attccaaggt tgaggacgta cggtttccat tctatcactt
     1681 tgtcgacgtg cgcgacgtgg caaggagcca tgtggatgca ctttctaatc ccgctgccgg
     1741 agggcagcgt atcctgctga tctcggggct tattacaccg cagctagtag tcaatatcat
     1801 ccgaaagcat ttttcagaac tacgcgaaaa ggttccggtc ggtataccgg atagggtact
     1861 gcctgagggg gtgcatccta ccgggtggga tatgcgagtt agcttagacg tgctctccaa
     1921 gggaaagggc agtcagtggc agtatattgg cttggaggag agtgtgaagg atgcagtgca
     1981 gtctatgctt cagcacaacg tgttgcctgt ataatgtaac gcaattttgt acttacatgt
     2041 caatttgaca gagacattag tgaattgtag acttctcagt agacacattg gactcaaaat
     2101 cccctacacg ggcttcttat atccacattt cagccatcat tggtgtgtat tcacatctga
     2161 gcatccgaaa aacatggctc ccaagttact cagagcgcaa agcagcactc ctcctcaaca
     2221 ccttatccat caactcctca ttaattgcag tagacacacc aacctccttc cctcgtcgaa
     2281 cccagtaccc attgatgaag tgaatctccg tctcacgcct attccgcaaa tcaacaacca
     2341 tcgagcaagt ggtctctctc gtccgctcca agataccatt caccgtttct tctagcctgt
     2401 caaccgcaaa tcgttgctct actccatcca cacctcttaa ctctggcaag cgcagcacaa
     2461 tacttgatat ctctgtgagg atcgcccgac gtagtttggg aaattcgaaa agaatgctgt
     2521 tcttcgagtc gtggagcgca cagactgggt tacaaaatgc gttcacagct aacttttcca
     2581 gctggatctg gaacacatcc gaaaaagaat acgatttggc ggatagtctg ggggagactg
     2641 gcatgttgtg cagcatgtat tcggatccgc ctctgttttg tagctggtta ccggtctctc
     2701 gggtgtttgg ggaggactgt gaatgcgggc gaggaaccaa tcccaaagat attgcggatg
     2761 cgccagtgtg tatcgcatta aagggagacg caagcgttac tccgtgcgaa atgactccgg
     2821 caaggtagtt tggtctggtt gcggggtctg ggaacaggtg ttcgttgacc tcgtcgatca
     2881 taccacatcc attttgtagg aagagaacag tcgaggctcg agagagtcgg gatctgaggg
     2941 cacggagggc agataccgtt tgcgttgctt taactgttac aactagattg tcgatctggt
     3001 ggtctgctgg agagtcggcc ggggtatgcc aggcgccttg tttgtagatc tcgaggttgt
     3061 agtcgctgtg gtgcatcgtg tcaccggtca ctggttttag agttatctgg cgattattcc
     3121 gtatgtattc ttggtagagt gattctcgat ggaggagtaa ggtgacagct ggagggttcg
     3181 ggatgtcttt taggccgtga gccgtgaatg tgccaatgct gccgagaccg aggacgtgga
     3241 tcgtcggacg agtggtatgg gattgcagtg gcatgcttgt agagtagcac cgtgcaaact
     3301 gtttgtatat tggtttttgc attgttatcg agctctgtct gtgttgaaca ccttgctgtg
     3361 attgagaatc atcggtttta tcgaagtgtc gcttcatgta cgccttacgc cctacgccct
     3421 gtggcaagat gaagtttctt ccagcttttc cagtctaatc ctcaccttca tcacacccac
     3481 acctagctat tatccgaaca ttgaatgatt actttacata caatgtatga gaacatggct
     3541 aaccagcaaa gtttacagtt tacacgattt tgttccaacg ctcccacccc caaacccgcc
     3601 gaacgtgtcc ccgctagcct ttggctctcc ccttcaccac acattcgaga catcctgaag
     3661 acaatccttc ggcttacaca aatttccggt ctcaccaact ctcatagcgc catactatct
     3721 caccataggt ccatctcttc gttcaaagga tagccgaaac gctctctaac ccgctcatcc
     3781 ggtacctaca tcccatattt tgaccacagt gacgatcgct cccggagata cagatcggct
     3841 gttgcatctc cggttggcag cagcatcagc agccctgaga ttaggaagca cagactgctc
     3901 agggtatact acgctggggt ataagtacat cacccgagag tgaaggaaag aaagggagac
     3961 atgggaccct aagtacacgt tgtattcatt cggttcatga ggcaaagttt tcgccagaat
     4021 catgaacacc cttctcttta tcgaaatgca gatccttaaa agtagccagc cactccggat
     4081 tatctgcaat cgtctggttc catgaatcat ctgagtcata cagtactcgt ctggattcct
     4141 gctggaacat ctcgtcactc ggaatcacgc cctttttcat ctgttcctgt gcaaaccggc
     4201 tgagatgcag cgttagcact tgggtgaacg agctgagccg ctcgggggca acacccggtg
     4261 caagagcccg caagggcaag gctacacttg gagccgaagg ggctgtaata gtgctggcct
     4321 ctttctggtc tttcgcgtcc caattagctc gggagtaaat ctgcgccaaa tgatcttcca
     4381 catcgcaatt tgtcgctgaa aatggaatca tgctctgaga ttctgagccg atgaggtaag
     4441 ggggcaatgc attggctact agggcggcga aatcaggcgg gaagtcatgg tcgccgcgcc
     4501 actctgccat tgtcgagcct gtccgaaagt gttcggctag atggtccaca cgctctttcc
     4561 aggtcatcag cgcttgactg cagaagccgc accgcgaggt gatggcggac tgtccgatcc
     4621 tccaactgtc gagttgtggc ggggagtcga cattgtgtac gagccgtaga tgctgcacta
     4681 agtgatcttt acggcggaag gaacgtcgac tgctggactc gtcctcgcaa gctgtggcgg
     4741 cgtgttcctc cagatggtcg gagtcggggt tagtaagccc acagaaggca catctagtca
     4801 tagaaggttc attagaggac ataatggtag tgccataagg cgcgcagtgc catgcttcca
     4861 aggtgacgtg gagcgatttc tcatgtcgtg cccagtcata cttgcttttg aaccggtcgc
     4921 agcagaatgt gcagcagtat cgacgctgag cagtggtcga agtaatcttc gtctttcgtc
     4981 tcgtagtctt gcccgccctg atgttgccgt gacgcccctg taccgccaat ggattctggg
     5041 ccgatgagct tgaacgcccg gatttctggg tgcttcgcga ggatgcacta gactccccgc
     5101 tagtaattga agcagctctc cgatacccat ggaacgcact gtagtcgtcg ccggggtttt
     5161 gcaagttggt ttggacccct tggcttgggt tgtctctgag agcatcgatg atatcgggga
     5221 ttaggcaacc ttcttcctca gggggcgaat tccgccagcg ctccatagga ctgaagctgc
     5281 ttgcttttgg tatcatcaca gagtatgctt gtgtccccga atgcctcgtt aagtaccgac
     5341 ttctacgccg tggaagttgg ccccgcgggg cagtagtgtt gttggtggtc gcatcctcaa
     5401 atagctcgct tggcacagcc cgttgctggg cgttgggcag gaccgctggt acttgctgga
     5461 gattcagatc ataaggctgc ggattggaaa gattaaaatg cctggagtcc aaatcatgcc
     5521 cgtcgagcgt cgagtggcac agcagagatg gatcgatgaa ctcttcgcca cattccatgc
     5581 tggcagctgc agctattcta agcaaagttt ctcttcagag tttcggataa taagggtctg
     5641 cgggctaacc attatcgcat tctcctaccc aatagacatc atggaaagga agcaagagta
     5701 acttcattcc tcttcatcct attttgggtg ccggtgcttg agacattatg taatctattc
     5761 tgcctcaggc caacagggtg gcggtcggcc tctcagcaaa tcccgatgaa actatccagt
     5821 tcatggttga ggccctgtgg ctacaatttg agccttgaat ggtcactgcc gacgtgacag
     5881 agattgggta gcactccgca aatcgattca aaatacacca tctattgaat taagggggaa
     5941 ttgtcctcta cattgtccta gtagacagta gcggcggcaa tgtatcctgg ccattgaacc
     6001 gtgattgatt cctcatcgac atgtgatgat acatgaatga atgccttacg aatcaaatat
     6061 tggagcttca atacactcca taagacccat tgacattgtt gttctcgctg aagaccaagc
     6121 agactgggta tcaacgcggc acctgcagac agactcagcg tgcatctgtc ggctaaattc
     6181 tcctgggagc caaccagcct tgggacaata atgataagca cagcccatca aacttgaaat
     6241 gcatgtgtag tattcagctt ctccttgtcg cccaacattc catttcctcc tgcacctctg
     6301 accccatact gtgagctaat acatgtaagc cagtgtaacc gaaagacggt cacaagtcac
     6361 gggtgggtga agttcaacgg gctttgaaat ctcaccatgc cagtttatga tatcttgttc
     6421 atactgaaag actgtaatat ctatccgtat aatatctctg attttttgaa acaaaaatgt
     6481 gagtatcaaa cgcacttcat ttctagacgc aagtgacgac aagacaacaa cactatttgt
     6541 ttcagcaaga tacctagcaa tgaagcacag gccccccaca tctagcaatt acgacaaaaa
     6601 gctcaatatt tcgtagatcc ccttcgaatg tccaacctga ctctctagct ctttgaccat
     6661 atgatccgcc tcttccaaca aggaagcgag ccgttcccga caatattcga aactccctgt
     6721 cgagtcgata tactccacag catacttctt caccgaatcg tcttcgctcc gttgccgcaa
     6781 tatattcagc agatgatgat tattcgggtt actgtggata ctgtggatga tcaggaagga
     6841 aaatttgccc tccgtcaaat cctcacagaa tcccttgttc ttcgtgtata gtccgctctg
     6901 caaattttgg taatcatctc gaatctgaaa gatcaccccc aacaaatctg ctagctcgat
     6961 gacatcgctg catagagtca gtctgctgtg tgacaaggag ctttacagta ttgtgacaga
     7021 tatgtaacac ttgccttttt gtttcagttt ccaactgcat aagcttgata gccagtcgga
     7081 aaaggccacc cgtcttattt gcgatcatct cgatatagtc ctcctctgtg ggacaggtca
     7141 gagaatcccg ccagtacaag tccatacctt gaccgcggtg cagacggagc agttcttcgg
     7201 tgtatatttc gtacgcttcg ggatgattca gttcgcggag ccgctcctgc gccaaaaagt
     7261 acgcataatt agcagagttg atggtctggg caatgccgaa gatgctgtgg gccactggga
     7321 ggccgcgtcg aagtttggaa ttgtcctgaa tgtcatcgat tcttcaaaag atcagctagt
     7381 ttccgagaca ttaagaactt cgatcatgtg ggaaatgaaa aggaatatac agtagggaag
     7441 ctgtgtggag caatccaaca atctctgtaa tgatattcaa tttctcttct gggatgcgca
     7501 gccactcgtt gaatgcgtgg atgaatttgc gacgaatatc cttcccaggt gatttaagaa
     7561 ggtagtcaag tggtcctcga acaatctgtt atctcacatc agacgaagac tgaccatgga
     7621 caggaagctt cagacctttt ccttgtccag aaagcttgtt tcagactgtg aagtactcgc
     7681 agcttctata ttggtgggtg atgatggtat cgatgcagag aagacacccg aggaaacaaa
     7741 aggaaagtag ggggtattca tcttccaggc gtcaggtgtc tctgggctga acattggaaa
     7801 tccgagcatt ttttcgtctc ttgtaggtca agagcactgt acggatcgag gttgatggaa
     7861 aagaaggcta ctaagaagga actaaacgtg tgctttcgag ggagaagcat tgatatctct
     7921 caggtatata agagtacgcc ttctattagt ctcaccttat agaactgttt tggcttctgc
     7981 tacatgtttt gctgtcactt ggcgtagctt tactgggcac ttgtcatcag caaattagtg
     8041 acgtcgacaa gctcttggaa gcacgtctag tcagcaagca atctcagaga acattcatca
     8101 aatagccttg ctactggtac tggtgagttg ctccgtgtcc gcgtgttaac cttgtgtttg
     8161 ccaaagactc ttctacatcc gggatgctat gcgttggttt caaacaagac caggtcgctt
     8221 aggtcgcccg agtcatagag attggctcga taaagtttct ccgttcagct tcctagccaa
     8281 ttctccttat aactcgagaa tggtcattgt ggccagctta tcggcaaaat agcagaatac
     8341 ctatcgtgaa agcgctgcta atgcaagatg cggcgtagtt atacggtacc atcttacact
     8401 gtcgtacaga ccttatccct gtgcctcagt gcaaagctta tcgcagtcag taatgagaat
     8461 cctataggat agagagatta aattctctta aataaggagt attgcaacag tttccatcac
     8521 taagcaaagt attcgcctat ctacattccc gcttacggct tcacactctt gacatccatt
     8581 ttttccttcc gaccccaaac ttccagccaa tcctgtacgg aggcacttga tttcttcaaa
     8641 tcccacaagc aggcgctacg cacatcttct ctttgaatta ctcgtagagc attacggata
     8701 ttatggggtg agccgtattc caaggcgcgc gctatcagat gaccctcggg agcatccaat
     8761 gccaccacta tggggaagga aagctcgccg ttgcgcaggt cttctgccag tgcacctttg
     8821 gctttcgcat aatcggtcga ataaacgttc ttgcagtcat tctgcagctg tgagcaccac
     8881 ctgtgtagac gtcaatcagc cataatcccc aatgctcgga tgtctttgca catacgccac
     8941 cgtagtcatg gtagcatcca tggacttatt ctctagtacc agctgaccga gcaaacgaaa
     9001 caatgcgccc gttttcagcg acgccatttg ccgatatgct gcatcccgtt cctttggacc
     9061 cactggaaag ctggcaagac catcccttcg ccatacaagg gacatatctt ggccttccag
     9121 gatctcctcc aggcactgca tcagaaaggg cgcaagacga ggaaattcgt ggacggtccg
     9181 gtttaaaagt tgtgtcacgc gatagtaggc acggttcgca gtctctgaag ggccgtatat
     9241 cttgtgcgcg gcgggatgtc ccttgcgaaa gttactcccg tccgagatct tatggggtta
     9301 ttagctctct actccatatg ttcagtgggg tgctgcactt acatcatcaa ccagtatcaa
     9361 acagagatgg atgccgtcca taatctcaag gaccagctgg tacttcggcg ggtcctccaa
     9421 cttgaggctg ggcgccagct tgtcgacaaa tggggcccag tggtgtttac cgtagatttg
     9481 gcggatgtag ctgtaggggc actccagtga agtgatccga gatggttgct tcttgccaac
     9541 aagccaagcc cgctttgttg tcggaagtgg gttcaatatg cgatcccata ccagcgccgt
     9601 tatcgggacg gccagtaagg cgagaaaagc cagcgaagtt tgcggaagat gatgctggag
     9661 gggctccatg atgatagccg tgttaagaaa tgagaaaggc tccatataag tcattcgact
     9721 agatgatgaa gacctggatc ttgtaaccgg aatagctgca ggacgtacag ggcagatata
     9781 tgaatgatgt tatctctcga gcgtaccttg gctgttagct cgctaagaat tcaaggaatt
     9841 cttcgtcgca taatatatgc tttaacaaac aaatctgcaa ctccgtacag gcttaagtat
     9901 gcgaaaggcg tccaattggc tggtcacttc aacttatcat gaaagttgct gcgctttggc
     9961 ggctgcatta catgtcctga gtcagtcagt gaagatataa cttttgacta ctgccccacc
    10021 ttaatatgcg cccccaacaa tttggcccat agctattaat gctgcatacg catttactga
    10081 cctgggtaaa tatatttggc gctacaatct gaacatgggt agatgaacgc gcaatctaaa
    10141 tccacaaaaa gccaattcgc tatcaagaat cgaataaaga accattacta tcatcgttga
    10201 atcatcgcat ctgtcttgtg gaatatttgc actccctatg tagtgttcag ggaatttctg
    10261 gtacgaacac atggattttc cgagggacta cgcagaatat gccgcagatt ccaaactaat
    10321 gtcctggctt gacattggcg ccagtgaaat ctcattgact tttgtggcaa actgcaggtg
    10381 acaggatagt cctataattg aggcttcgat gcaggtctcg tcatacggcg ctggcaaact
    10441 ccatatcata aattgcagca aacatgttag ccgtccgtac ccatggccag cagtatgtcg
    10501 ccagatttcc aatccgtcgg cgcacatatc caaggacctt ttaattaaat tatagtaatg
    10561 gcaaggaatg ctcagtatca attactttaa tgtacagcat tacgagagta cctgccgcat
    10621 gtaagatgat atttttctac aacagataag ttgggcccta tgagtatccc actataacct
    10681 tcttagccgt tctggtgcaa cacaggcgct gctattaggt actacagagt tggcacagtg
    10741 agggcttgct aaatcgagtc aatcggcccc gggggcaaga aactccgaca ctccatcctt
    10801 gctaccagtt tgtatgggga tagtgccaca gccattccga tcaacattgg caagaggaac
    10861 ccaactggct atgctgatct ggtttgcttt gattctgact aatccacaca aatatggtat
    10921 attgggcttg ttagttgctt gtatgtacgt ataaaaagtc ttatctgcaa agaaaattaa
    10981 ggatgatcac agtagttgtg tcctggccca tgtggctgcc cgttgatcaa tacttgcggg
    11041 ctcaagttta ctagggaata attaatggcc atacccatta ggccatgctc ccaccgcaaa
    11101 agtcaaataa gcctggagga ccttcaattg aacatagcac aatagtatac attgtaatca
    11161 gacgacatac aacattcaaa gttatactat aaccccacac gtaactagac aagaacagcc
    11221 gtcagaattg ctaccgccat tccgaccacc tgcagcatcg accactggga acctgcagaa
    11281 gcagacccag tgtacaatgc attaacggca cttgcgcttc ttgtgctagt aaccatagcc
    11341 gtgctcatgc cagcttggtg actgctctgg ggccagacat gtgctgaaga gacaggagta
    11401 ctgtggttcc aacccaatcc tgagcccaag tacgaggtgt acgaatacgg ggagggaggc
    11461 acagtgggct gagcaagatt ggaggtctgg gccattgtga tggtactgcc atactcggtg
    11521 caggttccgt cattggagca tgattcgacg ataatcgtgg tggtgtaggt tgtgtctgcg
    11581 gctgcacctg agcccgcacc ggacactgcg ctggagtctg cagcagagcc ggcatccgat
    11641 ccttcacttg actccgcact tgagcctgca cttgagcctg taccctgagt gctagtctca
    11701 cttgcagatg tgggctgcga tccagatgaa acaaccttgg gggagctacc cgctgagttg
    11761 gcagtctgga ggagcgtggc agcggtcgta ggagcagcca tagcatcaac accttcggtt
    11821 gggacggata catattctgg atatactgtg taaacggtcg ttcctacaac gagggtctca
    11881 gtcgtgacat aagagtcaga cgatgaactg cgacagtcat ccccagtgca gctggcaact
    11941 gtggcaatgc gggtgctcag gatggtggag gtggtgagtg atggtccctc ttccgatgct
    12001 cttgtgacag atggaagagg agtctttgct ttggtattag agaccttcgg gactgggtac
    12061 acagtcgtcg cgacaaccag tgtctcagtg cttgcataag tcgtcttgga cctcatggga
    12121 cagttggtca cggaagaggg acatgcagta acagtgatca cacgggtgct caagatcgta
    12181 gaagtagtaa tgtcaaatcc acccatgctg ctccagttgt caccaacagc cacgctagcc
    12241 gaaggatgag atgcagactg ggtagcaatt acagcgccgc tgctaccagt gatgtcggct
    12301 acggggcaaa cagtggttga gactaccaag gtctcggtgg tcacataggt cgttttcgac
    12361 ctgagcgggc aatttgttac cgaggaaggg cacgcagtta tggtagcagt gcgagtgctg
    12421 aaaaccgtgg aagttgtaag ctccgctcca ccgctgccat gaccattgtt gacagcagtg
    12481 tcggttgctg tcggcgaggc agaatccgtc cgagtcgcac gagcagcctc ggtaactggg
    12541 catactgtgg tggacaccac aatggtctct gtggtgacaa gggttgttct cgagcgtgga
    12601 ggacaatctg ggactgcaga tgggcatgca gtaattgtgg ccgtacgagt agagaggacc
    12661 gccgacgtag ttaactgcag tgtggaagac tcggcgaatg ttgcagctga cgaggatgtg
    12721 aaaatgttcg actgaggaaa tgcggcccca acaggggtta gcgcgggaac tgcgctggat
    12781 gtgattccag atagtctggg gacagggagt gaagagctcg gaattgctct ggacgaagcc
    12841 gaacactggc ttcgctgagg taaaggccgg gatacatagg tccaatgcgg gcggggagct
    12901 gctgaacgac tgggtaccgg ccttgaactg ggagttggcg attcccttac aggcgaggta
    12961 gagggtgagg ggactgcact cgacgagggt accacgatga ttgatggagt aggagttgct
    13021 gccttcgaag aaggaacaga cgacgaaaaa ctgggtgtgc atggcctgcg actgggcaag
    13081 gaccttgagc tataggacca gtgatgatgc gtatgtgcga tagcagagga agtagtggta
    13141 gaagtcgcag ctgctggctc aacaacgacc gtcatggcga tgctggtttg catcaataac
    13201 gaggcgagga tccatcctcg catcagcagg tgacccattc tgacagcgat cgactcagct
    13261 caaccgtatc aaatgaagat tattaaggaa agtagaattg attgatcaag agtaatcagg
    13321 tagcatgaaa tataaatgaa tgacttgtgg ttgaattcca atgagaaagg actgtcaaaa
    13381 gagggtgtgg gaaaccgagc cctgattctc tcttgcaaga ggcgggtcac tgtatataga
    13441 tcactcaagg atttcctctc ggtcggagat tcggcaaaga gaatacaaag aaggaatgca
    13501 cacgcgacgg agctattttc tggttcctgt ctcagccttc gtattcagct ggactattga
    13561 cgcccactgg gtcgcgggtc tatcaatgac ggcgaaaata gccgacaccg aatcccacca
    13621 gaattcaggg acggagtact tattgcgagg acactccgaa cctaccgagg gttttgagta
    13681 attgccatac atatttactt catattttgc caacctgtga gaatgtcaat ccagggcttc
    13741 attgtcgccg cgggctttct gctcggtcgg gtcgcagcca tcacccccgc ggccagctcg
    13801 cctgtggcca gcagtcaggc ctatgtgcct tcggtgtcct gccgcacgca gctgggaaca
    13861 aactcagtgg cacttgttcc taccactacc attacgcgca ccatccatga cccgacaccg
    13921 gttgttgtct tttcgacgac acaagacact gtcactgtga cccctgacgc ctcgactgtc
    13981 accgtcaccg actatgagac gaccacggcc atttccacag ctgacacggt cactgatact
    14041 ttctcgacaa cctcaactga gtatgacact gcaacggtga ctatcactcc tgctgctgtc
    14101 actgccattg tatctgtcac catctccacc acgagcacga gcacgtccac aattgccagc
    14161 tcttcaggtt tttctcccat tgtggaaaca ctgcctacag ctactgctgc caagcggtcc
    14221 ttgatcgagc aggacgattg ttcctcctgg ctggacgact atcaatatcc tcaagaggtc
    14281 gagtgccacc agaagattct tgtcaagacc acaaccgtct ccacagtgac ccaatctccc
    14341 gcgactgcta ccgcagtcac tcctacatcc accgtgactg tgacaaacac tatcaccagt
    14401 acttcagtcg tggccccttc cgatgtctca accacgctga gctacagtac cacgtccacc
    14461 atcactgaaa ccacaaccgc ggctgccgaa acaaccaccg tgacgtcaac taccagcgcc
    14521 gtggccgccg tggctaccac caccttctac gaggcgtgcg ggtctagcaa tattgctggc
    14581 gaccctctct cctctggatt tggctctttt gcgggccaat acatgtacct ggtcaccttc
    14641 accaacgttc ccggtgaaag cttgactgtt ggcgacacca gctctgcata tgattgctgt
    14701 gtcagctgca tggagagctc tacctgcgcc atgtcctact acaacgcggt aacttcctcc
    14761 atcagttact gctatctcat tcacaccaca acctgctcgc agtcttccgt ttacgccaag
    14821 gcgtctgttc atgacgcttc gactaccatg cagatgtcca acggaaattg cggtcgtgtt
    14881 gtgggcgtac aggggtaacg ttatagcaaa tgtagaaggt tgtcattata ccttagagaa
    14941 acactagtca aactttaccg cttataatat tacatccgct gctcgatgca ttttttaatt
    15001 gtcctaagta gagataagtc aacatgcctt cagcagactg cgtagaatgc agacctattc
    15061 cctctctaca tctcgagtca gtacctcccc actcaagatc cacgctagtt gaaaatctca
    15121 accacataac accactttgc cactcgtatc gcggagatta aatcgacatt agcgcatggc
    15181 catcaaggaa ctcacgaatc tgatcggcac tttttacctt ttagatattg ggatcaggta
    15241 cccggtgggt ctgattggcg gggacattta ctagcatcca agaaaccggt ccagactgaa
    15301 aactattgcg ccaccggaac ctttaacacc gaacagctcg gatatctccg agtgctaagc
    15361 tcgaatgcca agttcatgtc gtattccctt ctattggtgg gtgaacatac cagagtaagt
    15421 tccgttctcc agaaatagta cgcaaaaaaa atgttgttcg atcaatgaga acggatgaat
    15481 taaggtcaaa gtagccgaga gactggattt atttttcgct gtgaatcatg gcaataaccc
    15541 cttttttact ttcgactctg aaagagctat taatttggcg gtgcactgcg tacagggagt
    15601 gctgagttag aagaggtccg attgtccggt cgaaaacaaa tgcaggcaaa gtctggaatg
    15661 cccctggaca cctcaatcta gctcccagca gcttactcac gtcaatcagg caaacacgtc
    15721 tgttgtgagt cacggtaagt agatagttgc cacgtcgttg gccatgtgac tgtgagaaga
    15781 aatccgatgt gtccaattgg ccataccgtc taaaatgcca caatatgagt ggttgttgat
    15841 tggaaagata aggtagcgcg agctaaagcc gttttagtaa atcttggatg ctgattagcc
    15901 gctgtgtgca ttattcttcc acagccactt aggctgccaa atcatgcata ggatagattt
    15961 tggcgttgaa cggctgctct gagagtcacg ttatgattgt ttcagcttgt tcactttatg
    16021 caactaaggt atgacgcaat gcatctaacc cattgttacc tgcgtctcgt aggcatgacc
    16081 ttacttgtcg tttgattcga atactgaaat ataatttcat gtagaagttc aaacatttaa
    16141 ggcattgaat aaaagtactt tcacatagtc catatattgt gtaaaataca ccttacttgc
    16201 aatgtgcggt tgttgtgtac tgttgtcggc gttctgaagg cattcgaagc ctgcggtcag
    16261 ctatagccaa tgatatcgct tactagctgt ggtctagaca ctagtagact acatcacgca
    16321 ttagattaaa ttaacaatgg gccccctgac tcacgtcgag gatatagtct gtcggctaaa
    16381 gtgtctatgt cgtcattcaa ttcacaaata cccaggtgtc cagaccactg gccaagctcc
    16441 agagctttgg ggtagagact tcgatgcgag atattcatgc tgctttatgt gagatatacg
    16501 cagatgttag ggcctagata tgatgtggtt aatagctctt agctataata tgggggtcct
    16561 ctctcgatat acggcaaagt ctgaatcccg ctcttcccat actctgaata cctgcgccga
    16621 aggcatgaac aagatgttgc taagatattt tttccgtgag gctgaacatc acagctctca
    16681 gcgtcatggc attctagaac ggaaaaatgg gcacttgtgt ttccgccaag cccgtgagat
    16741 tttagctgtc tacccatcac atgcttgtct acgggaatgt cactgcgtta ggaaggccaa
    16801 tattgttgcc ttgaagcatt ctatacctca ctttagtata tcagccacat acggagtata
    16861 tataggccac ttcctctcgg gtaactgtcc ttttcatcca gcattgcttc attaccagct
    16921 tctcagactc ttactacaac ctcactctcc acctcgtaca aagaggaact tgaaattgaa
    16981 tcaaccacat tcagaatata aaaactactt tatctcgtgc gattattctt tgtgtcctgc
    17041 attgctttat caggacgcct tccatatctc ctacgatctc attctccagc tagtacgaag
    17101 gggaacttga acttaaagtc atcatccaaa ccacattatc cagtcaccat gtctcctaca
    17161 tctcgagctc cgaccatgcg catgaaccct tctggcacgc gtgacatgcc cacattcatc
    17221 gacgaacttg ctaaagatga ggcgaaaaac caaccaaagg gcgactcgga gagtactttt
    17281 tccgacgctt cgacactcca atgcaacgag caatctccga aaccaaaacg tgggcttttc
    17341 cgtaggctca tctcttcatc gctatccgca aatcaagatg cagtcaagaa gtagatcaag
    17401 ggggtggcca tctttgattg gataatgagg ttttgaattg agccctttga gagggtgatt
    17461 gcggtttcta catgccctct acttaatgtg tggactactg tcatattgtt tcaacctttg
    17521 tcagaagtgg ggtgttcggt atctggcatt ttcgtatctg cgctagttga tttcattggt
    17581 cagtatgcgc atgttttggg tgggaagtgg cgcagtggtt attgggaaaa gcatatcact
    17641 tccctcttat tctagttatt tcttaaatct tgtgaccagt ttcctctcca tatactcctc
    17701 tttctcactc ctgctagtta ccgcttcaat tatggcgtcc ctatgcctaa atgaaagtca
    17761 ctggcctcat atcaattcac aataattact ttcgctgctt ctaagagcct ccgagctcag
    17821 cttttacttt gatgtcaatg tgtcgctcag gcagccctgc agaagtggct gagcagatga
    17881 actaggagga gctggcgtgg cgcatgatgt tgctccatca aaaaagcgcc cagtatactc
    17941 tgtatcaatg cagcttatgc tattggtggg ttttatgcaa gggtatgatt gcggggttat
    18001 actcaacaat gctctgtccc cgaaagccac aggtgttgtg gtgcactgac cctttggtgc
    18061 taggactagc aaggctgcct agtaggcgat aacaccatgg gtgtagagaa agccttgcga
    18121 tacccataaa tatagataag ctctccttgt cacatagcag cagcagcaac aagttcaacc
    18181 ctgccaactg cttccaaatg ttgagccaga atcaaaggac agctgatatg ttcgctatac
    18241 tttccaacaa atgaatccct agctgatgcg atctgggggc tacagtcgta aatctttgtc
    18301 actggctcta gctgccaata gttagtgaac agccgttcac agcgttgttg atctagggtt
    18361 tgattgggcc agaatccaag ctccaagaca gactattcgg gtgggggtgc tgctaggcgc
    18421 aacctcaatt cagcctttgc gggatcgatg gggtgacccg cgaggctgag acacttaact
    18481 tgcgggggta cagtttcccg tttaaaacaa cgttcaaaat aagtctcata ttttgagcat
    18541 gaaacccggc ctagagtact ctcgtagcgt aaataaagag taaatatgtt gacaggttaa
    18601 gcggccgaaa gataagagaa gtatgtactg tatcctgtgg atgatagctg atccgttagt
    18661 attgaagggt caaggatacg ccaggcaagc tgaccaacga atgcaaggct agatagttgg
    18721 cgcagcacat gcagcaacat cacatgataa gtccctcccc aggggttggg gaggggttaa
    18781 aagggccatc ctcctcgcat ctgattgtcc ctcctcaccc atcccctacc aacccgtcct
    18841 ctcctacaaa gctcttttct tatatactcg ctttgaccgc tctgatactc gttataaccg
    18901 caccaagcaa ctgtacgacg acacaatgcc ttcattttct gctcttgcgg agagggccca
    18961 ggccctgcaa aaccttatcg ggtacatctt caatgacccg aagcgtgcga tggaagcact
    19021 agtcgctgct ggggtttaca tgcccggatt gatcaatcgc acggatggtc acaagcaact
    19081 tgccctcgtt ggggatgccg ttctcagaat ggttctggcg ctggacggat acgaagcccg
    19141 aaagggcaga ggtagatatt attccatttg accagaatca cattctcatc ccttatggca
    19201 gaattcacca acaatatcct ctcaacgaag gccggcaaca catacatcgc ccaggctggg
    19261 cgtaacctgg gcctggacaa acttgtcatt gtcaatccag cccaggccgg aatggtatcc
    19321 gacaaagtca tggccagcgc cgttgaagct attatcggag ctgtcttcat ggacagcgat
    19381 ggctctgttg agtccgtgcg acctgtcctg actattttgg gccttggctg gcccgcttga
    19441 gctccatgac tttgcgtgaa ctacctatgc aaagtgacgt gatctggaag ctagttgctt
    19501 accagtaggg cgtacaaagg cccgtctgca tcggtaccgg actcctgcta cgaggaagct
    19561 cctcttgcca ctcaggacgg cggcacttga
//
