LOCUS       NKJJ01000006.1         50276 bp    DNA     linear   PLN 19-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   NKJJ01000006
VERSION     NKJJ01000006.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 06:54:43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 574082
            Orig. end    :: 624358
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..50276
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[594082:594700](+),
                     [594939:601884](+), [601942:602223](+), [603375:603622](+),
                     [603693:603934](+), [603960:604167](+),
                     [604287:604358](+)}"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(20001..20618,20858..27802,27861..28141,29294..29540,
                     29612..29852,29879..30085,30206..30276)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..50276
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..50276
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T1PKS"
                     /region_number="4"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     mRNA            join(1285..2096,2160..2419,2497..2915)
                     /locus_tag="CAN33_10335"
                     /product="Cytochrome P450 family protein"
     gene            1285..2915
                     /locus_tag="CAN33_10335"
     CDS             join(1285..2096,2160..2419,2497..2915)
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002974"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="InterPro:IPR036396"
                     /db_xref="PFAM:PF00067"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 261.5; E-value: 2.5e-79)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_10335"
                     /note="SECRETED:SignalP(1-22); EggNog:ENOG41; GO_function:
                     GO:0020037 - heme binding [Evidence IEA]; GO_function:
                     GO:0005506 - iron ion binding [Evidence IEA]; GO_function:
                     GO:0016712 - oxidoreductase activity, acting on paired
                     donors, with incorporation or reduction of molecular
                     oxygen, reduced flavin or flavoprotein as one donor, and
                     incorporation of one atom of oxygen [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]; GO_process: GO:0055114 -
                     oxidation-reduction process [Evidence IEA]"
                     /product="Cytochrome P450 family protein"
                     /protein_id="ncbi_CAN33_10335-T1"
                     /sec_met_domain="p450 (E-value: 2.5e-50, bitscore: 165.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MALHGLHALAVIALLWPLLLQAIYRAFRASSCQRFRLLHGCQSAP
                     KGGRRSLPFGIDNLAVLWRATRENRVLETVESDFRSSGHTTMVQRHLNRRMVITCEPEN
                     IRTILSLKSEDYSVESRNQAFGPLVNTGILISDGVTWAHSRGILRRNFTRSHLANFEPL
                     EQTLQDLISLLPRDGVTVDLQPLFLRYTLDIASGLHLGQSLHSLRQKAASNGKPTRIDE
                     FKEAMGHAAKDVARRHHLGVLRYFFIDLRARKSYRTYQAFVDQLVEEALSGPYVALHEW
                     LEQTTDRRRLRDEVILMLLTSGDTTASLLGNLFSMLARHPTVWQKLRAEISSTLQGRRP
                     TYEELPRLQYLRYCINETLRLIPSIPLVDRVARRDTVLPVGGGPDGKSPLMVPQGSQMV
                     CCMYSLHRRVNHFGSDAEEFRPDRWATRQPGDEFMPFSTGPRACPGRQFALTVTEYVTV
                     RLVQLFPRLEGRDAQPWQGDLSAMLLPKNGVKVALWSA"
     mRNA            join(3356..3632,3685..3777,3838..4745)
                     /locus_tag="CAN33_10340"
                     /product="major facilitator superfamily protein"
     gene            3356..4745
                     /locus_tag="CAN33_10340"
     CDS             join(3356..3632,3685..3777,3838..4745)
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1137:Major
                     facilitator superfamily MFS 1 (Score: 288.5; E-value:
                     1.1e-87)"
                     /gene_kind="transport"
                     /locus_tag="CAN33_10340"
                     /note="EggNog:ENOG41; GO_component: GO:0005887 - integral
                     component of plasma membrane [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="major facilitator superfamily protein"
                     /protein_id="ncbi_CAN33_10340-T1"
                     /transl_table=1
                     /translation="MDMETKIAEPASPAMTDELSDLPHGYPEGGLEAWLVVLGAWCAMI
                     PSMGLLNCLGILHAWTSKHQLQDYSESSIGWIFGAYSFFLYAAGAQTGPILDTHGPNYV
                     IIPGSIGMVIALIGFSFSQEFYQIFLSFSVLGGLSACTLFIPAISCIGHWFDVRRGYAT
                     GIACTAGGLGGVIFPVIILFAAPRIGFPWAIRVIALISAVLLLISCLTLKTRLPKDKNV
                     GASVDFHALREKKYAATTIAVFLVEFAVFIPITYISSYGIHVGLDNTLAYALSIFLNLG
                     AVPGRLLPGLVADRLGRFNVMVVTSVICAALTLALWLASGANMPAIICYAVLFGFWSGA
                     AISLTPVCISQVCKTEDLGKRSGTTFTIASVGTLTGIPIAGAIQQQNHGAYWGLIVFGG
                     VLYAASAVAFAVARGICAGWKLKAKF"
     mRNA            join(5334..5467,5524..5600,6274..6377,6431..6678,
                     6732..6956,7022..7720,7785..8263,8368..8486)
                     /locus_tag="CAN33_10345"
                     /product="Fungal specific transcription factor domain
                     family protein"
     gene            5334..8486
                     /locus_tag="CAN33_10345"
     CDS             join(5334..5467,5524..5600,6274..6377,6431..6678,
                     6732..6956,7022..7720,7785..8263,8368..8486)
                     /codon_start=1
                     /db_xref="InterPro:IPR007219"
                     /db_xref="PFAM:PF04082"
                     /locus_tag="CAN33_10345"
                     /note="EggNog:ENOG41; GO_component: GO:0005634 - nucleus
                     [Evidence IEA]; GO_function: GO:0003677 - DNA binding
                     [Evidence IEA]; GO_function: GO:0008270 - zinc ion binding
                     [Evidence IEA]; GO_process: GO:0006351 - transcription,
                     DNA-templated [Evidence IEA]"
                     /product="Fungal specific transcription factor domain
                     family protein"
                     /protein_id="ncbi_CAN33_10345-T1"
                     /transl_table=1
                     /translation="MDLKQKVISLKARLCCRFPPVDKVDEPNKRDARQTTPSPDTATVK
                     NETAMLPTYSESCETFTPSYPVFYNDQNDIHHVTNAAGESYAVKLITTAVVSAVQLRVT
                     LGTVPPKPLSPETRPVATGDLQPTEQLVVDQDPPVPHQAVEIPFFELDSVRFSADPGGT
                     RPHTPSAFKERHTHQTIQTLDGLGVHCKFNDRGFLSFHQVHFRNAGGVPFDEKIPCHFL
                     VSSDQLYEPSKAQLLPPEPLTTHEQLNHLVPPECGQRLIVLFMRFIFPTLPIISRSHFG
                     LAAAGTVPDQTILQKTSLCLLAAIYASAQPFAKFDDYLCLLDAYAPPPTDLLWRMVLDL
                     VLRDIHTARLSTLQAGILYLHRPVSVTESAVADSAFTWSLVGMLVGVAMSLGLQLDCRL
                     MGLPLWEKRIRRRLWWAIYAEDKWRCLLIGRPSYIGSDDWDAADLNDDDFVMSESLRLA
                     LQQPPSASHSSHILLSAQPFQQFILLSRIADELQRSLFTLKASQRLSPDFHATLEIARP
                     LLQKLKEWYAHSPVSVRQPDHLPTTMDSIYCQSNCLRFACILLEVFVFRALLRPMVRSA
                     APPPLLEESFETTEFTNQFNDLLAQLFDADEIEPSMAIDMSDENGMGNAVLRAADNCAA
                     KVIRLVMRMTTSDLSSFWYRFSYCYCLYKRPRKTTLSVLKALWTFGVKHYGIRAQGVRP
                     "
     mRNA            complement(9005..9961)
                     /locus_tag="CAN33_10350"
                     /product="hypothetical protein"
     gene            complement(9005..9961)
                     /locus_tag="CAN33_10350"
     CDS             complement(9005..9961)
                     /codon_start=1
                     /locus_tag="CAN33_10350"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CAN33_10350-T1"
                     /transl_table=1
                     /translation="MPAASLIDQRASEPAKRDCSRECMATIVDQILASMVVHNPYTLPM
                     ATVYQATENSHPAALGMMTAWRTVTKAGPPSLLAIDTTQGSAYFALDVSEGSDTTESVL
                     RGRVKVVDQEITELELFINRYRGDHGFSFSAAELPSNYEVLMSPPDNRTKASRATLTAL
                     SEALFATSSNLSVSVDAKCQFTEVGWKVIDTGTYDNGTTTPLSCSWPTDHPTDEKARVG
                     LVIDEELGFVVTSGMIPGKVYPYQNVSAFIPDAMTSSQEAQDVWLNEAKAQGIKGLLAP
                     TEGTGETLEVLQYYNDALQAMQINVYMSGPNMTSAWL"
     mRNA            join(11120..11788,11841..11876)
                     /locus_tag="CAN33_10355"
                     /product="hypothetical protein"
     gene            11120..11876
                     /locus_tag="CAN33_10355"
     CDS             join(11120..11788,11841..11876)
                     /NRPS_PKS="Domain: PKS_ER (24-219). E-value: 3e-17. Score:
                     54.4. Matches aSDomain:
                     nrpspksdomains_CAN33_10355_PKS_ER.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR036291"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 119.5; E-value: 2.9e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_10355"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CAN33_10355-T1"
                     /transl_table=1
                     /translation="MSTETTRALIQPTTESNADGLTLQTDVAVNSNPAKGEHLIHVHAC
                     SPCAGELLWPRNFPPPTKRLLIPCPDVSGTVVSAPPDSPFQPGAEIYARTSYVRPGNAR
                     DYTIATTDELARKPESLTWVEAAAVPVSAETAWQILFINAGIVPPEAVMDIPRAQLAWK
                     GKRILVTAASGGVGLWVMQLAARVLGVEVIGTCGPDNVDLVRSMGAKEAVNYRATDLKA
                     WEDEHSRMLGGL"
     aSDomain        11192..11776
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_10355_PKS_ER.1"
                     /evalue="3.00E-17"
                     /label="CAN33_10355_PKS_ER.1"
                     /locus_tag="CAN33_10355"
                     /score="54.4"
                     /tool="antismash"
                     /translation="TDVAVNSNPAKGEHLIHVHACSPCAGELLWPRNFPPPTKRLLIPC
                     PDVSGTVVSAPPDSPFQPGAEIYARTSYVRPGNARDYTIATTDELARKPESLTWVEAAA
                     VPVSAETAWQILFINAGIVPPEAVMDIPRAQLAWKGKRILVTAASGGVGLWVMQLAARV
                     LGVEVIGTCGPDNVDLVRSMGAKEAVNYRATDL"
     CDS_motif       11609..11671
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_10355_0001"
                     /evalue="2.00E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="CAN33_10355"
                     /score="17.2"
                     /tool="antismash"
                     /translation="GKRILVTAASGGVGLWVMQLAA"
     mRNA            complement(14756..16363)
                     /locus_tag="CAN33_10360"
                     /product="GMC oxidoreductase family protein"
     gene            complement(14756..16363)
                     /locus_tag="CAN33_10360"
     CDS             complement(14756..16363)
                     /codon_start=1
                     /db_xref="InterPro:IPR000172"
                     /db_xref="InterPro:IPR007867"
                     /db_xref="InterPro:IPR012132"
                     /db_xref="InterPro:IPR036188"
                     /db_xref="PFAM:PF00732"
                     /db_xref="PFAM:PF05199"
                     /locus_tag="CAN33_10360"
                     /note="CAZy:AA3_2; CAZy:AA3; CAZy:AA3_3; EggNog:ENOG41;
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]; GO_function: GO:0016614 -
                     oxidoreductase activity, acting on CH-OH group of donors
                     [Evidence IEA]; GO_process: GO:0055114 -
                     oxidation-reduction process [Evidence IEA]"
                     /product="GMC oxidoreductase family protein"
                     /protein_id="ncbi_CAN33_10360-T1"
                     /transl_table=1
                     /translation="MSKTYEYVICGGGTVGCVLASRLSQAGHSVLVVEAGPEDYNDKIM
                     SPVAAPHLHGTEWEYNLMTAKQPGLGNRSVPNYVGKLLSGSSGINYGLWTRGHSVDYDS
                     WAKAVGDERWNYANMLKFFKMAQTHHDPTGSPEKYGFSGPISTTAAARTYPLREQIRNA
                     MLAAGLEYNPDTNGGSPLGFGPFTENWKDALRQPASKAYDLSKATVLTNSVIARVNFDD
                     SKTATGITLTDGTQYTASREVLVTCGAIKTPQLLMLSGIGPQQHLAQHNIPTIADLPVG
                     ENYHDKISATFFWKLRNPEKGYALGSPLFNKPEFRHGNPIEWVATVPTPHAELIEAAQK
                     DRIDAEDPYLQEPRGNVEVMVAYAPIAGGGSEFRVPMDGNHISSPVVLLLPTSRGSVTL
                     ASADPTADPVLDPRYLDTETDRAAIRAGMRVALRVMETDSAKEVIDGETPPPGHEPITS
                     ASSNADLDRRVQIVGSSFFQNGGTAAMGTVVDTQCRVKGVQNLRVCDASVLPLPLAGHY
                     QAPMYAFGEAVADMLLAQ"
     mRNA            join(17333..17509,17576..18146,18210..18556)
                     /locus_tag="CAN33_10365"
                     /product="putative integral membrane protein"
     gene            17333..18556
                     /locus_tag="CAN33_10365"
     CDS             join(17333..17509,17576..18146,18210..18556)
                     /codon_start=1
                     /locus_tag="CAN33_10365"
                     /note="EggNog:ENOG41"
                     /product="putative integral membrane protein"
                     /protein_id="ncbi_CAN33_10365-T1"
                     /transl_table=1
                     /translation="MGSTSSPGYDSSATRVPIIIGVCVPMVVLAILATALRIWARVMTN
                     VKLWWDDWLCIVGLAFPAQPFAILPSIFDFVQINNGFGRPMATVPADKLVTYSLFLYIL
                     MLFYNLGLAFFKLSCLALYIRMFGIHRWIRYMSYVIGLMVIAWVLANELVLAFRCHPID
                     LAWKGTAEQQAKFCVTQTNIFIAQSGPTIFFDLLILIMPIRVVWGLHLQSAQKLGAILV
                     FSLGLLVTVISMIRLADTLHSTDTDLTYGYVELGMWSAVEPVTGLICCSLMTYGPFIKK
                     LRQAGKGYIRGKSSHHRQSHSSNSFATQNKLTGHRSAEYDQSDLELTFCSFSNEAPVVG
                     KADTFGKIHDGAINITHEFQVRRD"
     mRNA            join(20001..20618,20858..27802,27861..28141,29294..29540,
                     29612..29852,29879..30085,30206..30276)
                     /locus_tag="CAN33_10370"
                     /product="Beta-ketoacyl synthase N-terminal domain family
                     protein"
     gene            20001..30276
                     /locus_tag="CAN33_10370"
     CDS             join(20001..20618,20858..27802,27861..28141,29294..29540,
                     29612..29852,29879..30085,30206..30276)
                     /NRPS_PKS="Domain: PKS_KS (400-821). E-value: 1.5e-149.
                     Score: 490.2. Matches aSDomain:
                     nrpspksdomains_CAN33_10370_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (925-1204). E-value: 2.9e-63.
                     Score: 205.6. Matches aSDomain:
                     nrpspksdomains_CAN33_10370_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (1319-1409). E-value: 1.3e-09.
                     Score: 30.3. Matches aSDomain:
                     nrpspksdomains_CAN33_10370_PKS_DH.1"
                     /NRPS_PKS="Domain: cMT (2048-2235). E-value: 2.9e-60.
                     Score: 195.1. Matches aSDomain:
                     nrpspksdomains_CAN33_10370_cMT.1"
                     /NRPS_PKS="Domain: TD (2290-2535). E-value: 1.6e-37. Score:
                     120.7. Matches aSDomain: nrpspksdomains_CAN33_10370_TD.1"
                     /NRPS_PKS="type: Type I Iterative PKS"
                     /codon_start=1
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR005123"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="InterPro:IPR013217"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR020801"
                     /db_xref="InterPro:IPR020807"
                     /db_xref="InterPro:IPR020841"
                     /db_xref="InterPro:IPR026992"
                     /db_xref="InterPro:IPR027443"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="InterPro:IPR032088"
                     /db_xref="InterPro:IPR032821"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="InterPro:IPR036736"
                     /db_xref="InterPro:IPR041068"
                     /db_xref="InterPro:IPR042104"
                     /db_xref="PFAM:PF00109"
                     /db_xref="PFAM:PF00550"
                     /db_xref="PFAM:PF00698"
                     /db_xref="PFAM:PF01370"
                     /db_xref="PFAM:PF02801"
                     /db_xref="PFAM:PF03171"
                     /db_xref="PFAM:PF07993"
                     /db_xref="PFAM:PF08241"
                     /db_xref="PFAM:PF08242"
                     /db_xref="PFAM:PF08659"
                     /db_xref="PFAM:PF13489"
                     /db_xref="PFAM:PF13649"
                     /db_xref="PFAM:PF13847"
                     /db_xref="PFAM:PF14226"
                     /db_xref="PFAM:PF14765"
                     /db_xref="PFAM:PF16073"
                     /db_xref="PFAM:PF16197"
                     /db_xref="PFAM:PF18558"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2OG-FeII_Oxy"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 234.3; E-value:
                     4.3e-71)"
                     /gene_kind="biosynthetic"
                     /locus_tag="CAN33_10370"
                     /note="EggNog:ENOG41; GO_function: GO:0016740 - transferase
                     activity [Evidence IEA]; GO_function: GO:0016491 -
                     oxidoreductase activity [Evidence IEA]; GO_function:
                     GO:0003824 - catalytic activity [Evidence IEA]; GO_process:
                     GO:0055114 - oxidation-reduction process [Evidence IEA]"
                     /product="Beta-ketoacyl synthase N-terminal domain family
                     protein"
                     /protein_id="ncbi_CAN33_10370-T1"
                     /sec_met_domain="PP-binding (E-value: 7.7e-10, bitscore:
                     33.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.4e-62, bitscore: 205.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 1.3e-151, bitscore:
                     499.0, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.4e-32, bitscore:
                     105.8, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="2OG-FeII_Oxy (E-value: 3.4e-13, bitscore:
                     43.9, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MEQPALVIFGPQISWPSNSSAERIRRDLVQEPSLAPFADAIRKIP
                     ELWASLVEIEPRLRETQGRRNLEQLRDWVEIGSLPRRDSPDEILPNGFATPFTVIAQSI
                     EYWRCFPRGGLQWLHSRSEAGPALEGMCTGFLTAIAAATSKDSTEFFTMAAIAVRLAAC
                     IGTFVDLNGNTSDGTGEARALVVRWSSPIQESCLLRILEEQPNAYVSVLKDETSRTITV
                     PASEIPSTAEKLLMNGLRVHALELKGRFHHASNEDIANKLLQMCQLNADLHFPDAQGLL
                     TTLRRNSDGRRLSKGPLHIIAIRSLLLDQVDWLSTMTSALESAVIKDKPPKILVFGSVN
                     VVPHCLIQRSGARVCVSNDMIQPLSNITTTVKDFVPEPDMTKPGVKSLPDAPGCDNHDN
                     SIAIVGMACRFPGADSAEEFWELLECGKSMLSVLPESRFPTKGLRRSADDTVFWGNFIQ
                     DPDQFDNRFFQISSREAASMDPQQRLILQVAYQALESSGYFDGQRKPTHTNIGCYLGVG
                     SVDYEANIYSHQPNSYSALGSLKAFVSGRVSHYFGWTGPSITYDTACSSSVVALHSACK
                     ALLSGECTSALSGGVNVITNPALYQNLRAASFLSPTGATKAFDAAADGYSRGEGCGLFV
                     LKRLENALADGDQVLGVIAASAVNQTQREYGTSITAPVSKSQQSLYRHVLSQAGLEPSD
                     VTYIEAHGTGTPRGDPIECESIRTVFGSTNTGRQQTLYFGSVKGNIGHLEAGSGAAALF
                     KSVLMLQKKKIPKHMNFNKLNPQIPPLEPEKLAIPTKTISWDAPFRAICISNYGAAGSN
                     GALVLREAPEPLKSTCARPTGNGPLRCQLISIAADSAESLQAYCNQLLRYLADVNERHF
                     PDVAYKLARIQNPAHKYRLSFVTRSISELRSFLSAQSHVTPTPSFSGTVKPVVLCFGGQ
                     SKSSVGINKQLYDSISLFRHHLDRVEAACQALGKTIYPFIFSKEVIQDSVTLHCCLFAS
                     QYACARSWIDAGIKVATVIGHSFGQISALCVCGVLSLEDAVKYVIERALLFDINWSAEK
                     GTMLALKGDTQIVTRLVSTSQVEIACYNGPRDVVVAGSIQAIEGFQSRAKAAGIDVRCL
                     DVARAFHSSLMDPALPQLRRIANALTFYRPYIPIQTCTQGHGRDSFDPEFLVDHSRQPV
                     FFHDAVQRIESQLGPCTWIEAGSSSFGTTLASRIASQLNSFIPVDIGGPSPAESLANAT
                     LKLQALGYNVQFWAYHRSQRDAFRVFNVPPYQFAKSKHWLEFKEFNSLAKESSHTDDND
                     QHSKLLLFVQSRDREKGIAEFKVNANSDYFRACVSGHAVLGHSLCPASLYLELAAQAAV
                     YICENESPVLPQVEDLQISAPLGLNPSATIKLLLSLKEPKVWRFSLLSTTGAEDIHHAS
                     GTIQVPANADFLVSESSLYERLIGADRCNSILQDASIKSINGLVYNVFGAVVDYKDFYQ
                     GVQRISATKSEASGVVSLPVAAAGIMQDSVYDPLALDNFLQVSGIHINCFRDFGRQEVY
                     VCTSIGKLKVYQSLEKVRDQSWLVYSNTKQGGPGVLESDIFAFNKTTGSLMVALFGVRF
                     AKVSVNSLTKTLSALNHGKPVQRLKDSTPPSTPLSNLGLGTSPKTELDGNVLLRLQRLL
                     SRVTDCPVEDILQVNSLEALGIDSLMRSEVTAEIRQEFGLDISTDTLAKASTLFHLTTL
                     ISSSQKWPVQIVNTPSSSESHTTLSMRDSTSSTLKDILSAITDIPVDEIGNDSTLEALG
                     IDSLMRKEVQSELRKNLGRADIPENLHEYSVTSLAAYLADQDCGKRNDLSCGTPPGSVS
                     LGRHCDIKALGSHTQLMAPEMISGLEERQELVKRNDRSQLFQLSSPPKPLCSSTVGGFT
                     LKDLAASFEEIKGAFDQLSDESQFLNFYAQVHPRQMKLATAYVVEAFRSLGCPLSSMSP
                     GESLSLSPVSYEPRHGNLMKQLYRLLQDAGLISLDNLGEYKRTSKPVDCTSSADLLDAI
                     IQDFPQHQLEHRLLSITGSRLASCLSGELDALDLIFGDRTAKDLVSDVYLKAPVFVTGT
                     KLLCKFLLSCLRQRTQPIRILEIGAGTGGTTADVVRCLISSNIPFEYCFTDLSPSLVAA
                     ARKKFKWCPNMEFNVLDIEQEPPSVNQYDLVVSTNCIHATRNLTATTKNIHKLLKEGGI
                     LCLVELTRNLPWFDLVFGLLEGWWLFNDGRQHALAHELFWKDSLRQAGFSYINWTTGDT
                     KESEQLRLIISVKMDHQYDLSKWETGSEKCTGDNFEIVTSRQPLSVYSTPDLLKEPGLS
                     GSVVLLTGGTGNLGTHVLHQLINRADVRRVICLNRLTTNDDPIQRQRRALRDKGIDLKE
                     RQWEKIEVLEAKSSHTALGLQTEQYQRLRDQVTHIVHNAWPMSFKRSLHTFEPQFKTLQ
                     NLLKLCHEAKYGARLLFISSIGVVGRHPNTFANKPVPEDPVRDCQSSLGFGYSQAKYHC
                     EQIINRALEQDTRLEASYVRIGQITGSQHFGLWNTEEHVPALLRTSQTIGALPHLDGLA
                     SWLPIDIAAATVSELLLDTAHLRMVYHVENPVRQPWCELLGYLSAHLRLPIIPYKEWLS
                     RMETNGDSVTGSPNPAKNLRDFFKNDFLHMSCGEAANDVCQAIRVACLHTGFFQVIGHG
                     VSMSTMTRAFEASRRFYALPLEEKQKLDITKHLGFRGYDGIGTQSYGGDTLPDLKESFF
                     IGRDVSQSHTDYGRILTGPNIWPSFQVLPAVAFKESVEALFSALMELACKILEILARTL
                     PYGEGIFDRFKRDPATPMRAMDAAAVDDERQLGASAHTDFGAITLLLQDQVSGLQVHDS
                     DTGNWVDVPPRQDSIVVNIGDMITRWTAAPGESITVEQHMVECIRSSYASK"
     aSDomain        21440..22702
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_10370_PKS_KS.1"
                     /evalue="1.50E-149"
                     /label="CAN33_10370_PKS_KS.1"
                     /locus_tag="CAN33_10370"
                     /score="490.2"
                     /tool="antismash"
                     /translation="IAIVGMACRFPGADSAEEFWELLECGKSMLSVLPESRFPTKGLRR
                     SADDTVFWGNFIQDPDQFDNRFFQISSREAASMDPQQRLILQVAYQALESSGYFDGQRK
                     PTHTNIGCYLGVGSVDYEANIYSHQPNSYSALGSLKAFVSGRVSHYFGWTGPSITYDTA
                     CSSSVVALHSACKALLSGECTSALSGGVNVITNPALYQNLRAASFLSPTGATKAFDAAA
                     DGYSRGEGCGLFVLKRLENALADGDQVLGVIAASAVNQTQREYGTSITAPVSKSQQSLY
                     RHVLSQAGLEPSDVTYIEAHGTGTPRGDPIECESIRTVFGSTNTGRQQTLYFGSVKGNI
                     GHLEAGSGAAALFKSVLMLQKKKIPKHMNFNKLNPQIPPLEPEKLAIPTKTISWDAPFR
                     AICISNYGAAGSNGALVLREAPE"
     CDS_motif       21902..21949
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_10370_0001"
                     /evalue="3.30E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="CAN33_10370"
                     /score="16.1"
                     /tool="antismash"
                     /translation="GPSITYDTACSSSVVAL"
     CDS_motif       22091..22129
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_10370_0002"
                     /evalue="2.80E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="CAN33_10370"
                     /score="11.0"
                     /tool="antismash"
                     /translation="FDAAADGYSRGEGC"
     CDS_motif       22328..22375
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_10370_0003"
                     /evalue="1.40E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="CAN33_10370"
                     /score="11.2"
                     /tool="antismash"
                     /translation="YIEAHGTGTPRGDPIEC"
     aSDomain        23015..23851
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: False"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_10370_PKS_AT.1"
                     /evalue="2.90E-63"
                     /label="CAN33_10370_PKS_AT.1"
                     /locus_tag="CAN33_10370"
                     /score="205.6"
                     /specificity="Minowa: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="consensus: mal"
                     /tool="antismash"
                     /translation="CFGGQSKSSVGINKQLYDSISLFRHHLDRVEAACQALGKTIYPFI
                     FSKEVIQDSVTLHCCLFASQYACARSWIDAGIKVATVIGHSFGQISALCVCGVLSLEDA
                     VKYVIERALLFDINWSAEKGTMLALKGDTQIVTRLVSTSQVEIACYNGPRDVVVAGSIQ
                     AIEGFQSRAKAAGIDVRCLDVARAFHSSLMDPALPQLRRIANALTFYRPYIPIQTCTQG
                     HGRDSFDPEFLVDHSRQPVFFHDAVQRIESQLGPCTWIEAGSSSFGTTLASRIASQLN"
     CDS_motif       23252..23356
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_10370_0004"
                     /evalue="2.30E-13"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="CAN33_10370"
                     /score="42.2"
                     /tool="antismash"
                     /translation="ATVIGHSFGQISALCVCGVLSLEDAVKYVIERALLF"
     aSDomain        24197..24466
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_10370_PKS_DH.1"
                     /evalue="1.30E-09"
                     /label="CAN33_10370_PKS_DH.1"
                     /locus_tag="CAN33_10370"
                     /score="30.3"
                     /tool="antismash"
                     /translation="GHAVLGHSLCPASLYLELAAQAAVYICENESPVLPQVEDLQISAP
                     LGLNPSATIKLLLSLKEPKVWRFSLLSTTGAEDIHHASGTIQVPAN"
     aSDomain        26384..26944
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_10370_cMT.1"
                     /domain_subtype="cMT"
                     /evalue="2.90E-60"
                     /label="CAN33_10370_cMT.1"
                     /locus_tag="CAN33_10370"
                     /score="195.1"
                     /tool="antismash"
                     /translation="TGTKLLCKFLLSCLRQRTQPIRILEIGAGTGGTTADVVRCLISSN
                     IPFEYCFTDLSPSLVAAARKKFKWCPNMEFNVLDIEQEPPSVNQYDLVVSTNCIHATRN
                     LTATTKNIHKLLKEGGILCLVELTRNLPWFDLVFGLLEGWWLFNDGRQHALAHELFWKD
                     SLRQAGFSYINWTTGDTKESEQLRL"
     CDS_motif       27107..27175
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_10370_0005"
                     /evalue="6.50E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="CAN33_10370"
                     /score="12.4"
                     /tool="antismash"
                     /translation="VVLLTGGTGNLGTHVLHQLINRAD"
     aSDomain        join(27110..27802,27861..27902)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_10370_TD.1"
                     /evalue="1.60E-37"
                     /label="CAN33_10370_TD.1"
                     /locus_tag="CAN33_10370"
                     /score="120.7"
                     /tool="antismash"
                     /translation="VLLTGGTGNLGTHVLHQLINRADVRRVICLNRLTTNDDPIQRQRR
                     ALRDKGIDLKERQWEKIEVLEAKSSHTALGLQTEQYQRLRDQVTHIVHNAWPMSFKRSL
                     HTFEPQFKTLQNLLKLCHEAKYGARLLFISSIGVVGRHPNTFANKPVPEDPVRDCQSSL
                     GFGYSQAKYHCEQIINRALEQDTRLEASYVRIGQITGSQHFGLWNTEEHVPALLRTSQT
                     IGALPHLDGLASWLPIDIAAATVS"
     mRNA            complement(join(31900..33088,33149..33516))
                     /locus_tag="CAN33_10375"
                     /product="major facilitator superfamily protein"
     gene            complement(31900..33516)
                     /locus_tag="CAN33_10375"
     CDS             complement(join(31900..33088,33149..33516))
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 216.4; E-value: 8.4e-66)"
                     /gene_kind="transport"
                     /locus_tag="CAN33_10375"
                     /note="EggNog:ENOG41; GO_component: GO:0005887 - integral
                     component of plasma membrane [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="major facilitator superfamily protein"
                     /protein_id="ncbi_CAN33_10375-T1"
                     /transl_table=1
                     /translation="MTTQPNEKDVLKVPPNHDMEQADTEVQRGEIKHGETRDFDPALQF
                     MVDGEIEYTPEESRKVLFKIDRVLMPLLCWVYLIQFADKTSLNYASLMGIREDAHLDPE
                     SQQYSWVSSIFYAGYIFWEFPTTYLLRRLPLGKYTSANILIWGVVLLCHVAADSYAGLL
                     CVRFFLGAFEATITPAFVLFTSCWYKQEEQAKRMGFWLACNGVAQILIAAIAYGLSGVQ
                     EASIPVWKILFLVLGLPTVLTGFLYFWFMPNNQIQAKFLSHREKHIAVDRIRGNFQGIG
                     NRTWKWAHFFEAFRDPRTYLYVLFSFLMNIPNGGITTFGSLIISSFGFSSRMSLMLNMP
                     MGLVDISCKLGLTYMSDRLLDRTLFAIIAILIPMVGGILMIVLPFHAKAGLLVGYYCIG
                     AAGTSWCLVMVMISNNTLGYTKKATVNGLQILAYAAGNWIGPQTFRSNQAPEYFDGKLL
                     VAIMYALAAATLLVIRLVNIMENKKRDRQASSDPDRENVIVGTEFLDLTDFEQPAFRYV
                     L"
     mRNA            complement(join(34496..34614,34682..34771,34832..35152,
                     35181..35655,35718..35747))
                     /locus_tag="CAN33_10380"
                     /product="Aminotransferase class I and II family protein"
     gene            complement(34496..35747)
                     /locus_tag="CAN33_10380"
     CDS             complement(join(34496..34614,34682..34771,34832..35152,
                     35181..35655,35718..35747))
                     /NRPS_PKS="Domain: Aminotran_1_2 (4-334). E-value: 5e-46.
                     Score: 149.1. Matches aSDomain:
                     nrpspksdomains_CAN33_10380_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="InterPro:IPR000796"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="PFAM:PF00155"
                     /locus_tag="CAN33_10380"
                     /note="GO_function: GO:0008483 - transaminase activity
                     [Evidence IEA]; GO_function: GO:0003824 - catalytic
                     activity [Evidence IEA]; GO_function: GO:0030170 -
                     pyridoxal phosphate binding [Evidence IEA]; GO_process:
                     GO:0006520 - cellular amino acid metabolic process
                     [Evidence IEA]; GO_process: GO:0009058 - biosynthetic
                     process [Evidence IEA]"
                     /product="Aminotransferase class I and II family protein"
                     /protein_id="ncbi_CAN33_10380-T1"
                     /transl_table=1
                     /translation="MDSTAIRESRVASCQALSGTGALHMAGMMLMRTSICDQTGYITNP
                     SWSNHRQLFESVGFSVREFNYASSSGVDMQSLFRAMTEADPMSIFVLHASAHNPSGWDP
                     TPEQWRKIGALMKERTLFPLFDAAYLGLTSDNYDEDAYAIRYFAEELNLQMGVCISFAK
                     SMGMYGSVGSQVNLCFTFQYLLSLTRSLILMGERTGLCAFVSRNHSIATNVESNLAQLI
                     RCDISNPPAFGAGIVATVLGDGGLFSQWQRDLMTMSSRITGMRKRLFGELTALGTPGDW
                     KKLTQQKGMFCVLGLTPDRVHYVKKFHHIYMAESSRFSIAGLNEGNVRYVAECIHQIVC
                     RREE"
     aSDomain        complement(join(34529..34614,34682..34771,34832..35152,
                     35181..35655,35718..35735))
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_10380_Aminotran_1_2.1"
                     /evalue="5.00E-46"
                     /label="CAN33_10380_Aminotran_1_2.1"
                     /locus_tag="CAN33_10380"
                     /score="149.1"
                     /tool="antismash"
                     /translation="AIRESRVASCQALSGTGALHMAGMMLMRTSICDQTGYITNPSWSN
                     HRQLFESVGFSVREFNYASSSGVDMQSLFRAMTEADPMSIFVLHASAHNPSGWDPTPEQ
                     WRKIGALMKERTLFPLFDAAYLGLTSDNYDEDAYAIRYFAEELNLQMGVCISFAKSMGM
                     YGSVGSQVNLCFTFQYLLSLTRSLILMGERTGLCAFVSRNHSIATNVESNLAQLIRCDI
                     SNPPAFGAGIVATVLGDGGLFSQWQRDLMTMSSRITGMRKRLFGELTALGTPGDWKKLT
                     QQKGMFCVLGLTPDRVHYVKKFHHIYMAESSRFSIAGLNEGNVRYVAECI"
     mRNA            join(36284..36679,36747..37286)
                     /locus_tag="CAN33_10385"
                     /product="Dihydrodipicolinate synthetase family protein"
     gene            36284..37286
                     /locus_tag="CAN33_10385"
     CDS             join(36284..36679,36747..37286)
                     /codon_start=1
                     /db_xref="InterPro:IPR002220"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="PFAM:PF00701"
                     /locus_tag="CAN33_10385"
                     /note="GO_function: GO:0016829 - lyase activity [Evidence
                     IEA]; GO_function: GO:0003824 - catalytic activity
                     [Evidence IEA]"
                     /product="Dihydrodipicolinate synthetase family protein"
                     /protein_id="ncbi_CAN33_10385-T1"
                     /transl_table=1
                     /translation="MVPLTPKFGVYTPLVTFFTEDKSLDIESTLTHAKRMAEGDVAGLV
                     LQGSNGEAPHLDHEERKYLVRAVRDHLNELGYVQIQLIVGCGAPSVRETLTHITEAKES
                     GADFALVLPPSYWVLAMSTDVIEGFFDDVASSSPLPVLIYNFPGVTGGIDISSDSTIRL
                     AQSNSNIVGCKLTCGNVGKLQRISSTLPTTSFAAFGGKSDFFLPALVAGSNGIIAALAN
                     IAPKVHVELLRRYENGDIKGAQELQSLLSHADGALVKVGVTGVKAIVAHCFKYGSGQGR
                     KPLRNSTIATLSPNILEPILRVVEREKMCN"
     mRNA            complement(join(37784..38192,38258..38589,38657..38842,
                     38906..38935))
                     /locus_tag="CAN33_10390"
                     /product="NAD binding domain of 6-phosphogluconate
                     dehydrogenase family protein"
     gene            complement(37784..38935)
                     /locus_tag="CAN33_10390"
     CDS             complement(join(37784..38192,38258..38589,38657..38842,
                     38906..38935))
                     /codon_start=1
                     /db_xref="InterPro:IPR006115"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="InterPro:IPR013328"
                     /db_xref="InterPro:IPR015815"
                     /db_xref="InterPro:IPR029154"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF03446"
                     /db_xref="PFAM:PF14833"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100:3-hydroxyisobutyrate dehydrogenase (Score: 121.9;
                     E-value: 5.8e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_10390"
                     /note="EggNog:ENOG41; GO_function: GO:0050661 - NADP
                     binding [Evidence IEA]; GO_function: GO:0016491 -
                     oxidoreductase activity [Evidence IEA]; GO_function:
                     GO:0051287 - NAD binding [Evidence IEA]; GO_process:
                     GO:0055114 - oxidation-reduction process [Evidence IEA]"
                     /product="NAD binding domain of 6-phosphogluconate
                     dehydrogenase family protein"
                     /protein_id="ncbi_CAN33_10390-T1"
                     /transl_table=1
                     /translation="MSPSIPQVGWYGLGSMGLGMSLNLQRYLQAKNLPPLRYSNRTISK
                     GDILRDAGAVPEEFDALVQKSNVIFTMISTDDVLIDLLERASTMGNSLKGKIFVDTSTI
                     HPDTSEWAAKRLKEHGATFIAAPVFGASPVAAAGKLIFAVAGPVTVVETIRPLIMNVMG
                     RSIIEMGEDVRKSSLLKISGNILVISFMEVIAEAQVFAEVAGISTQQMEKFIGNMFGSV
                     LQSYSKRITSGAYAPPLDTAPGFAAALACKDMKHALSIADSHNVRLHTLETASKRLNTA
                     REYAGENLDSSAIYGIARQEAGLSFWSANSRQQSESS"
     mRNA            complement(join(39103..39532,39595..40421,40478..40615,
                     40678..40680))
                     /locus_tag="CAN33_10395"
                     /product="hypothetical protein"
     gene            complement(39103..40680)
                     /locus_tag="CAN33_10395"
     CDS             complement(join(39103..39532,39595..40421,40478..40615,
                     40678..40680))
                     /codon_start=1
                     /locus_tag="CAN33_10395"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CAN33_10395-T1"
                     /transl_table=1
                     /translation="MVSNQCGEIRKPWVMQAWILYMIYGVYAGGEASLFRTAREMLRQI
                     VDAVREVGLSQQEVAMPESQSWLYDIGYPRGDESRTLYTRWTSYIAAESTRVALYTLFF
                     LDSHLFVPCNSRPLMSSMELGWELPFPTKLWEAKDPEIWIRRFGEYFGVSAFSFTNDLL
                     QRPRGLAAASLTMATQQVMTEAPGTELSAALEASPFAAFCVLANLDTLVRDFTRCYYQM
                     PPSYSDPNPFHILTQSQTKSVYMAIRNIGKIVKDAATASDSPQSFQWRTNSLFIVSLQV
                     NLCRPDQLLIGGIVDNSLIAGLAASTHLMRGNFVAVRRSAPFPRQHISDDSQNVSYEAP
                     WVTVTSYGVLLCIWGALRCATTEIRDHLNTFNELPRTSEPCMLIFNALIEATLLYSPAT
                     RRDRDARDPRLWSTDREVFSTLLEQGQLLFADLVKVFCQQRLVWSIGPSMLAVLREIPD
                     AATCDSE"
     mRNA            complement(join(44376..45196,45253..45454,45509..45787,
                     45844..45950,46013..47112,47174..48335,48400..48585,
                     48654..48696))
                     /locus_tag="CAN33_10400"
                     /product="Hydantoinase B/oxoprolinase family protein"
     gene            complement(44376..48696)
                     /locus_tag="CAN33_10400"
     CDS             complement(join(44376..45196,45253..45454,45509..45787,
                     45844..45950,46013..47112,47174..48335,48400..48585,
                     48654..48696))
                     /codon_start=1
                     /db_xref="InterPro:IPR002821"
                     /db_xref="InterPro:IPR003692"
                     /db_xref="InterPro:IPR008040"
                     /db_xref="PFAM:PF01968"
                     /db_xref="PFAM:PF02538"
                     /db_xref="PFAM:PF05378"
                     /locus_tag="CAN33_10400"
                     /note="GO_function: GO:0003824 - catalytic activity
                     [Evidence IEA]; GO_function: GO:0016787 - hydrolase
                     activity [Evidence IEA]"
                     /product="Hydantoinase B/oxoprolinase family protein"
                     /protein_id="ncbi_CAN33_10400-T1"
                     /transl_table=1
                     /translation="MPKIPTTKPLRISIDRGGTFTDCISQVVDGPDIVAKILSVDPKNY
                     ADAPTEAIRRVLEQYYGSPIPRGTELDLRDVEWIRMGTTVATNALLERKGEKTALLITE
                     GFKDVLQIRTQSRPHMFDLTIRRPIPLYSKTFEVRERVTVQNCSDSDLRNIHLSSPEPV
                     DSVIAASGEIIQVLQPLDTASTKVQLQSIYEEGFRSLAVCLMHSYSFSKHELEIRDMAL
                     EIGFENVSLSHEISSRPKLVPRGNSTVVDAYLAPSIKQYLERFSRSFPNIGNSRTRLEF
                     MQSDGGLVPSSSLSGLHSILSGPAGGVIGFSRTCFDTETRAPVIGFDMGGTSTDVSRYD
                     GELDHIFETITAGITIHAPQLNVNTIAAGGGSILTWRNGLMSVGPESASSNPGPACYRK
                     GGPLTVTDANLALGRLIPEEFPSVFGVNEDEPLDKDIVLTKFKELTQVINKETGMSLTW
                     AEVADGFLQVANSAMCGPIRSLTLEKGHDVAKHHLASFGGAGGQHACAIASDLGIKRVL
                     IHKYSSILSAYGIGLAEVVHEEERVCAKAFEGSAIDVINDSLDSLVDYARCSKTMESFS
                     SIRACRFLNMRYDGSETSIMIPWESPDSDAKQAFVKAHHQQFGFTPVNRVVYVDTIRVR
                     AIGCSVSPEDSSYLQVKSLSSSTSATAAATPSSRVSTRFSSLGWVNTPVYHLNTLSEGT
                     EIEGPAMIIDKTQTVVVSPDSKATIARDLLILDIDPPAPKSTSSETIDPIQLSIFRHRF
                     MGVAEQMGRVLQNVSTSANIKDPLDFTCAIFTPEGELVANAPHVPAMIGSMAFAVKSQI
                     TEWRGKLQDGDVLLSNTPAYGGVHLPDLTVITPVFDAAGRNIIFWAASRGHHADVGGIL
                     PGSMPPTSKLLSEEGAIFNSHLLVRAGHFDEDELHRVLCVEPARFPGSSGSRRYQDNVT
                     DLKAQVAANHCGTQLMQRLIEEYSLPTVQVYMRAIQEAAELAVRTLLKRLAHERRGEDI
                     SAVDYMDDGTPIKLKVTINPTDGSAIFDFTGTGPEVYGNWNAPIAICNSAVIFALRCMV
                     NSDIPLNHGCIKPVQIIVPNGSLLCPDSEAAVCAGNVLTSQRIVDVIFKSFRVCAASQG
                     CMNNLTFGNDGGNGFGYYETIAGGSGGGPSWAGTDGVHTNMTNTRITDPESLERRYPVI
                     LRRFSFRSGSGGAGIYPGGDGVIRDIELRLPMSVSILSERRSFAPYGMAGGEDGQRGKN
                     TWITKDGRCINVGGKNSIRVQHGDRFVIETPGGGGYGALEDGVSRKRDESVVMPAFIPV
                     ANGSVAANRTLAEQV"
ORIGIN
        1 ttttacagca gaacaattct gtgaaggagg ctggccaaag cccagatgag gatagagggt
       61 acctgcttcg acatctatag ttcaatagtc caggattata gacgaatgat tattgctcca
      121 gaatggtgaa gtatttctag cagaccatga cgcgtacgca acatagaccg ctccatgtta
      181 ctgactgcga ctgtatttgg aggattgagg aaaggtagat aaaagtatat actacaaaac
      241 cgccataaca gcaaccgacg cctcgagtca cagtggcatc aatgccgggt gggcttcttg
      301 atacggtgag tcagatgcct tcgacccaac gcgggtgaac tagtcagtga atgtacgtag
      361 agtgatcgag catgtaaata ggtccatatt attcaaggcg cctagggtaa cgccacattt
      421 gaggaggcgt cgcatgaggc gtcattctat ctgcaccaac cactctatgg gataccatga
      481 ccagagtaac catactggtc taagtcttag aattggagat atagaggaca aacaaaagaa
      541 tacacactta ttctcatgcc tcctagtccc ggccagccga ctaagtaggt ccgtgtacga
      601 tatcaagaac gttgctatac tttgccatga aatgttttgt agggttatcg ccccaaatgc
      661 tgcaggacta atggcggtga agaacactgc ggccgttacg gcatgtcctg cacgggggct
      721 tacttgcata tcccgtcgtc agatactgcc gaatacgggc caaatattgg agaacagcag
      781 atgcccaggc accgatattg tctatattaa ttgccaatct ggtggtgaaa acccgttaca
      841 atactaaata tgcctattca gggcttgacc tgtcatttca ggtcagctca aaatctgggg
      901 attaggacgt gctcccacct caccgagccc caccagtatg gcgaagcttt cgcaggatta
      961 acgccaccat gatgcatgac cagatatgtt catttatgct tctgaaatgc ctctcgtggg
     1021 agacgaggaa atcaatatga gtatcaatta tctatctagg atcactatag tgttttctgc
     1081 tgtcaatgcc gatgaacgtt aatttctgca ttgcatatac gtagtgggtg catcggttgc
     1141 caactaaatg cgattcagag tccgaagaag ttctgggaga ggaagaaata cgatataagt
     1201 tgataccccc ggctcacctt ggatcaggag ctattccatt tcatctccaa catccacaca
     1261 taatatctcc ccacctcgtc catcatggca ctacacggcc tacacgcctt agccgttatt
     1321 gctttacttt ggccacttct cctccaggcc atctatcgtg cttttcgtgc aagctcttgc
     1381 caacgcttcc gtctgcttca tggatgccag tctgcgccaa aaggtgggcg gcgtagcctt
     1441 ccttttggta tcgacaatct tgccgtcctt tggcgagcga cccgagagaa tcgcgttctt
     1501 gagacagtag aatctgactt ccgctccagt ggacatacca ccatggtcca aagacacctc
     1561 aaccggcgga tggtcatcac ctgtgagcca gagaatattc ggacaatcct gtctctcaaa
     1621 tcagaggatt acagtgttga gagtcgtaac caagccttcg gtcccttggt caatacaggg
     1681 atcttaatct cagatggtgt tacttgggct cattctcgag ggattttgcg gcgcaacttc
     1741 acccggagtc accttgccaa tttcgagccc ctagaacaga cactgcagga tctgatttcc
     1801 ctcttgccgc gtgatggagt cacagtcgat ctgcagccgc tattcctgag gtatacactg
     1861 gacatcgcga gcgggcttca cttgggccag tcgctgcata gtctgcgtca gaaggcggcc
     1921 tcgaatggga aaccgaccag aattgatgaa ttcaaggagg ccatgggtca tgctgcaaag
     1981 gacgttgcac gtcggcatca tctcggggtc ttgcggtact tctttatcga cctaagagcc
     2041 aggaagagct atcgcacata tcaggccttt gtggatcagt tggtcgaaga ggccctgtag
     2101 cagaaggtca ggcgggatag caagaagtca tcgttggctt cggagtcctc ctgcgccagc
     2161 tcgggcccat acgttgcttt acatgaatgg ctcgagcaga caaccgaccg tcggcgactc
     2221 cgtgatgagg ttattctaat gctgttgaca agcggggaca ctacagcctc cctgctcggt
     2281 aacctgtttt ccatgctggc gaggcacccg acggtgtggc agaagctgcg ggcggagatc
     2341 tcgtccacac tccagggtcg gcggccaacc tacgaggagc taccgcgatt gcagtactta
     2401 cgatactgca tcaatgaaag taagtagtct gaaatgccct tccccaggta ctcatatgcc
     2461 cgtacactgg ctgattgaat gttgtgtctt gataagctct tcgactcatt ccctcgatcc
     2521 cgcttgttga tcgcgtggcc agacgggaca cagtcctccc agtcggtggt ggtccggatg
     2581 gaaaatctcc tcttatggtg ccccagggtt cccagatggt atgctgcatg tactcccttc
     2641 atcgccgcgt aaatcacttt ggctcggatg ccgaagaatt ccggcctgat cggtgggcga
     2701 ctcgtcagcc cggggatgaa ttcatgccct tcagtaccgg gccacgcgca tgtccgggcc
     2761 ggcagttcgc gctcaccgtg accgagtatg ttactgttcg tctggtgcag ctgtttccga
     2821 ggttggaggg gcgcgatgcg cagccatggc agggggacct gtcggcaatg ctgctgccca
     2881 agaatggggt taaagtggcg ctgtggtcag cttaaacgct atgatgattg atccgtgccg
     2941 atagttgaat tgatatatac tccacgagcc ttccatctat ttctgttcct tagttatcag
     3001 tcagctgccc tttcgccgaa gtactaatgc cccacaaatg ggcaaatacc caatcaccta
     3061 ctaaggacac cgagatttac cgaaggtcca acaagatgat gccgagcatt actagtagta
     3121 gagaatacat gctctaattt gtcattatct tgtccatcga gaacggggta taagtccctt
     3181 gcttgaacgg tcgctggctg gccatccatg aagcattcgt caacgcacag tggtcgtcca
     3241 gaatcttttg ttgaggcagt agcttccacc ccgacaatat tttcaggcgt cgtacatgcc
     3301 acattagtct gccccgacaa ttctggcttg caaaagcatc atagtatccc cccttatgga
     3361 tatggagacc aagatagctg agcccgcctc ccccgcgatg accgatgaac tttcagattt
     3421 gccgcacgga tatcccgagg gcggactcga ggcctggttg gtggtgcttg gagcatggtg
     3481 tgcgatgatc ccttccatgg gattgcttaa ctgcctgggc attctccatg catggacgag
     3541 taagcaccag cttcaagact attccgagtc cagcattggc tggatctttg gcgcatacag
     3601 cttcttcttg tacgccgcgg gagcgcaaac cggtcagtga ccccccccat cacgttgaga
     3661 cctactcgcg ctgagaaatc ccaggaccaa tattggatac tcatggtccc aattatgtta
     3721 ttatcccagg gtcgatcggc atggttatag cactgattgg ctttagtttc agccaaggta
     3781 gggagcatct gtcttccgta cagcagtggt acagttgatg ctgactgact gatatagaat
     3841 tctaccagat attcctctca tttagtgttc ttggcggcct atctgcgtgt accctcttca
     3901 ttccagcaat ttcttgtatt ggacactggt tcgacgtgcg acgcggatat gcgaccggca
     3961 tcgcctgcac tgccgggggt ttaggaggag tcatcttccc cgttattatt ctttttgcag
     4021 cacctcgaat tggctttccc tgggccattc gtgttatcgc gctcatcagt gctgttcttt
     4081 tattgatctc atgtttgacg ctgaaaacac ggcttcccaa agacaagaat gttggcgcat
     4141 cggtcgactt ccatgctctg cgggagaaga aatatgccgc aaccacgata gcggtcttcc
     4201 tggtggaatt cgccgtcttc atccccatca cctacatttc atcttacggg attcacgttg
     4261 gcttggataa cactcttgcg tacgcgctaa gtatcttcct caacttaggt gctgttccag
     4321 gacggctcct accgggctta gtagcagatc ggctcggcag gttcaacgtg atggtagtaa
     4381 catctgtcat ctgtgcggcg ctcacactcg cgttatggct cgcttcaggg gcaaatatgc
     4441 ctgcaatcat ttgttacgcg gtactatttg gcttttggag cggtgccgcc atcagtctca
     4501 cccccgtgtg catctcgcag gtgtgtaaaa cggaggatct gggaaagaga agcgggacga
     4561 catttaccat agccagtgtt ggtacattga cgggcatccc gattgcgggt gctatccagc
     4621 agcagaacca tggggcatat tggggcctga ttgtctttgg aggcgtgttg tatgcggcct
     4681 ctgcggtcgc ttttgctgtt gccaggggaa tttgcgcggg ctggaaattg aaagccaagt
     4741 tctaaaggct gcgatagaca agcaagacag agaatgacta ccaagtagac caaacgagat
     4801 actagtatat ctcgtcgggc agtggtgcgt ctgtgtctac caacagtatg cattagaata
     4861 gatatagaag tgaatcacat tgcctctttt tgtcattttg tccttttgtc tcctttttct
     4921 ttttcttttc ttttcttttt tttttttctt tttggcattg ccatagtgag gagtaatgat
     4981 ggcataaagt gttggattta ggagcagtct aacagggaaa ttctcggcga agtcaacatt
     5041 gaggccaaag ttgctcttct aggcaaccag atcggcgaaa tgcaggatgt agtcatcccc
     5101 actgcatgag tgaatggctg tcggctgatg aatgggccgg atggcttgtc ccgacgaggt
     5161 gtcttaccac tgcacaagca gacaaggccg aaagacaaag tgcttgatgt ctaaaggcag
     5221 gtagtattaa gactcatccc tcggccttat acctggcaca tataaagcgt ctctggccac
     5281 ttgcgctgcg tgtgaatttc gctgggaaat gcctcatgtt tctgctcctc atcatggatt
     5341 tgaaacagaa agtgattagc ctcaaagccc gactatgttg tcgtttccca cctgtggaca
     5401 aggtggatga accaaacaag agagacgcac ggcagactac accatccccc gacacggcga
     5461 cagtcaagtg agtgtccgaa gtcttcaaga ttacaaacca ttttgctcac ctccaatgtt
     5521 cagaaatgaa acagcgatgc ttccgacata tagtgagagt tgcgagactt tcacaccatc
     5581 ctaccctgtg ttctacaatg gtacctgact cactgccaca catatccgaa atcccttatc
     5641 attactattc acgagctaat ccgcaaaagg gatcaatgct ttggttcctg ttgtagggga
     5701 aatggatacc gctggtgatg gtcaacttga atgtcttgcg agactcttga tatggtgacc
     5761 gacgcgcccg agtttttttt ctttcgccga tcgacggcgg gggatattga agcaacgaaa
     5821 ttgtgaggtt tctagtggaa atctacataa tattgtccta gtcaattaaa atttatcaga
     5881 acagtatatt cgaaagaaca gccaaaacgg agtgaagctg tcgtagcaaa agtccttact
     5941 aactagtagt agtgcgcctt ccggcgatgc ttgagccaag caattcggcg gtgccatttg
     6001 gcggttgacg aatcaaacgg agaattcggc gaagtcctcg gccaactcgt tcttggccgc
     6061 tgtcgaattg acttcggcgg ataagttaaa tatcctttga tcggtagcgg cgattattga
     6121 tgttgctggt ctgactagta gtactccgaa acatcatctc gaattcgcaa atcaccgacc
     6181 gactgattgt cgcatggcgt caaattctcc aaatccaata accccccatc atctccaccc
     6241 tcgtacgccg cctcctacca ttcgtcccta tagatcaaaa cgacatccac catgtgacga
     6301 atgccgccgg agaaagctac gctgtgaagc tgatcacaac ggcagttgtc agcgctgtac
     6361 agctgcgggt cactcttgtt cctttgctcg tgttcgtcct cgccctcgcc ctcgacctcg
     6421 ttctcgtcag ggcaccgtgc cgccgaagcc gctctcacca gaaacccgac cggtggcaac
     6481 cggcgatttg caaccgaccg agcaacttgt ggtggaccaa gatcccccag ttccgcatca
     6541 agcggtcgag attcctttct tcgagctaga ctcggtgcga ttctcagcag atccaggcgg
     6601 tactcgcccg cacaccccct ctgccttcaa ggaaagacac acgcatcaaa ccatccagac
     6661 actcgatggt ttgggggtgt atcctaccag gtcaatggca cgtcagccga atctgacccg
     6721 tggctcctca gacactgcaa gttcaacgac agaggcttcc tctccttcca ccaagtgcac
     6781 ttccgaaacg cagggggtgt tccgtttgac gagaagattc cctgccattt tctggtctcg
     6841 tcggatcagc tctatgagcc ctccaaggct cagctgctgc cgccagaacc cctcactaca
     6901 catgagcaat taaatcatct tgtgccccct gaatgtggcc agagattgat cgtgctgtaa
     6961 gttgacattg ttaccacggt ttttccgttc agtagttgac atgagatggt tttctctcca
     7021 gcttcatgag gtttattttt ccgacgctgc cgatcatttc gcggtcgcat tttgggcttg
     7081 cagcggcagg cacagtgccc gatcagacta tccttcaaaa gacgtccctg tgtcttttgg
     7141 ctgcaattta cgcctcagca cagcctttcg ccaaatttga tgactacctt tgcttgcttg
     7201 atgcgtacgc tcctccccca actgatctac tctggcgcat ggttcttgac cttgtgctgc
     7261 gggacatcca cactgcccgt ctatcgaccc tccaagctgg aatcctctac cttcaccgac
     7321 cagtcagcgt cactgaaagt gctgtggcgg atagtgcctt tacctggtcc ttggtgggca
     7381 tgcttgtcgg tgtggccatg tcacttgggc ttcagttgga ttgccggcta atgggacttc
     7441 cgttatggga aaagaggatt cgccgtcggc tctggtgggc catctacgcc gaagacaaat
     7501 ggcgttgctt gcttatcggg cgtccatctt atataggaag cgacgactgg gatgccgcag
     7561 atctcaacga tgatgatttc gtcatgtccg aaagtctgcg cctggcccta cagcaacccc
     7621 cgtccgcctc acactcttct cacattcttc tcagtgctca accattccag caattcatct
     7681 tgttgtcgcg catcgctgat gaactacaac gctccctctt gtaggtctcc caactacgaa
     7741 tgtaatgttc atttacgcga tactgaccac ccctggcccc atagcacgct aaaggcgtcg
     7801 cagcgtttat cgccagattt tcatgcaacg ctggaaatcg cccgtcctct tctgcagaag
     7861 ctcaaggagt ggtacgcgca ctccccagta tcggtacgtc agcccgatca tttgcctacc
     7921 actatggaca gcatatactg ccagtccaac tgcctccgtt tcgcctgcat ccttctagag
     7981 gtctttgtat tccgcgctct cctgcggcca atggttcgct cggctgctcc acctccgttg
     8041 ctcgaggaga gcttcgagac aacggaattc acgaaccaat tcaacgatct actggctcag
     8101 ttgtttgacg ccgacgagat tgagccgtcc atggccattg acatgtccga tgaaaatggc
     8161 atgggaaatg cagtgctgag agcagccgac aactgtgcgg cgaaagtgat ccgtctggtg
     8221 atgcgtatga ctaccagtga tttgtccagt ttctggtaca gatgtatgtt ctgtcaattg
     8281 gagccacgcc tgtggatgag tcacatattc ggctggagat atactgactg agctagggtc
     8341 ccgtgtcgga tttgcaaccg tctccagttt cctactgcta ctgcttgtac aagcgcccac
     8401 gaaagaccac gctctccgtg ctaaaagcct tgtggacctt tggcgtcaaa cattacggaa
     8461 tcagagcaca gggtgtccgg ccatgaatct cggtttagtc agattagatg gctctctttg
     8521 gcctggactg gcgagaaatt actatctccc aaagcatgtg aaagaggttc tcgaaggata
     8581 ggaagcattt ctgcaggaat ggatgcatat gtggctgaag agctataacc acctccaccg
     8641 gtcggataac gcagacgtgc aaatgtacga gatcaggctc tgggaggcgt tccaagtgcg
     8701 tctattgact ttcaccataa ctgaaagata gaggctgata cactgtgatc aacttgatac
     8761 aatgattcag agcccggcac ctgccaggtg actgtttacg acttaagtac cgagatagag
     8821 gtaagcgaag gagtgctaaa gcaaacgacc ctaaagtccc cgacaccata tctcgcgtcg
     8881 actgaaaatt tagttcagct agcaaacaaa tatatgtgac gagtaaagta tgactccaga
     8941 tcagctcccc caaagacatc agtgcacttc catcgaataa gtctcctttg taccattcag
     9001 gtcttcacaa ccaggccgat gtcatatttg gaccgctcat atacacatta atctgcatgg
     9061 cttggagcgc atcgttgtag tattggagca cctcgagagt ctcccctgtt ccctcggtgg
     9121 gagccaaaag ccctttaatg ccctgtgctt tcgcctcgtt caaccacaca tcttgggcct
     9181 cctgcgagga agtcatggcg tccgggataa atgctgagac gttttggtaa gggtagacct
     9241 tacctggaat catgccgcta gtcacaacga agcccaactc ttcatcgatg actaggccga
     9301 cgcgcgcctt ctcatcagta ggatgatctg taggccagct gcaactgagc ggggtggtcg
     9361 ttccattgtc gtatgttccc gtatcgatga ccttccagcc cacttcggta aactggcatt
     9421 tggcatcgac gctcacggac aaattactcg aagtggcaaa gagagcctca ctcagggccg
     9481 tcaatgttgc ccgactcgcc tttgtccggt tatctggagg tgacatcaag acctcataat
     9541 tgctgggaag ctcagcggct gagaaggaga agccatggtc cccacggtag cggttgatga
     9601 acaattccag ctcggtgatc tcctggtcaa caaccttgac tcgtcccctg aggacggact
     9661 ccgtcgtgtc gctaccttcg ctgacgtcca atgcaaaata agccgaccct tgcgtggtgt
     9721 cgattgcgag caaactgggt ggtcctgctt tggtgacagt tcgccaggct gtcatcatcc
     9781 cgagcgctgc ggggtgagag ttttccgtag cctgatatac tgtggccatc ggcagggtgt
     9841 acgggttgtg cacgaccatt gaagccagaa tttgatccac gattgttgcc atgcactctc
     9901 gggaacagtc acgctttgct ggctctgaag cgcgctggtc aattagcgag gcggcaggca
     9961 ttggggaagc tcccgctgcg aggacgaggc ttgccactgt acttagaaac aaagacctca
    10021 ttattgctat gacgatactt tcttagatac caggcaagat acacgagagc ctttaaaagg
    10081 cacatctaat gctgcactaa aatgccgacc ggaccgctat gccagcatgc aatctaaata
    10141 gcttgataat tgcgcccagg aatcactacg actctcgaag caatcagcat agtctgccag
    10201 ggagtccaga agatcatgaa cctcgaatgc ccacattccg atgttcccca cgttgtccga
    10261 agatgaaaac cttccgacga attcttttag aagtatcgcg ttattggcaa cgatactgtg
    10321 cttgcagaag actagttgct tggctacgta agcgccgcct ccgatgtgga ggcacggaaa
    10381 gcggacccga ccccagactt tccatgcggg ggaaagtgta caacaaatgt tgagatctat
    10441 cgagattagc aaaagtgaaa tttccttcgt aaatggtcgg tggattaccc tgggacttca
    10501 gagagctgct ggctaaaagg gtcaatccaa ccaagccgct atacacgggc agtgttgcag
    10561 acagtagagg ctgaccgatc gcgatctaga gatcttttgc gtctttctta cgtggctggg
    10621 tatggacttc tttgcacagt gaaaggaatg tggagccagt cttgcaagac tcgccacggt
    10681 accattctca ttacccaaat agctgatatg ggtccccctt caattccatg cgactgagcc
    10741 acgtgtgaag gatattgcca cacgcggagt agggctgact tgctggtgaa cttgcactct
    10801 agtagccgga aacttggttg gggccggatg aaaggttatt tcgtcatcat tgctagaatg
    10861 ctaccctacc gggcatcgtc gaactgaata cgagaaaatc gcctgtctag atctaagatt
    10921 ccattcatgc cagccaatct ggccagagag ctgcggggat ttgagagtgt acccctctga
    10981 atacgagggc caggatcata cttcatggtt atacatatca tccctccgat caccacttca
    11041 tagtgtcaga atcgaatatg catctaccct ctctgttaac tcgtaattta caaaccacaa
    11101 ccacagccct aaaatcatca tgtctactga aaccacacgt gccctgattc aaccaaccac
    11161 tgaatccaat gcagatggtc taaccctcca aaccgacgta gccgtcaatt ccaacccagc
    11221 caaaggcgag cacctgattc atgtccatgc ctgctctccc tgcgctgggg agcttctctg
    11281 gcctagaaac ttccccccac ccactaaacg ccttctaatt ccctgtcccg atgtctccgg
    11341 taccgttgtc tccgcgcccc cagattcccc ttttcaaccc ggggccgaga tctatgctcg
    11401 tacgagttat gtcagacctg gcaacgctcg tgactataca atcgctacta cggacgagct
    11461 cgccagaaag ccagaaagct tgacttgggt tgaggctgct gcggtgccag tgtcagccga
    11521 gactgcttgg caaattctct ttatcaacgc cgggatagtc cctcccgagg ctgtgatgga
    11581 tatccccaga gcacaattgg catggaaagg caaaagaatc ctggtcacgg ctgcatctgg
    11641 gggcgtggga ctgtgggtta tgcagcttgc agcgagggtg ctgggcgtcg aggtgatcgg
    11701 gacgtgtgga cccgacaacg tcgacctggt gcgatctatg ggggccaagg aggctgttaa
    11761 ttatcgagcc actgacctga aggcctgggt agaggaggag gaggagggaa ggcgggtaga
    11821 tgtggttgtt gactgtgtag gaggacgagc actcgaggat gcttggtgga ctgtgaagga
    11881 cggaggcaca gtggtgagta tcttccaacc tcccagaaca ttatgtccat ggaaggatcc
    11941 gagtgcaaga ggtgttaagg atatattctt tgtaatggag ccaagtggca atcagctggg
    12001 ggcggtcact gagttgattg aattaggaaa gtgtcaggga agggtggata gtgtttggcc
    12061 gttggagcat tttcggtcag catttcaaag gctggcgact gggcacgcca gcgggaagat
    12121 tgtatttgac ttgagcttga acaggtagca gagactccat cgcagcggtc ataggtagga
    12181 aggtggttgt ttgtatagga taccaagttc agcccatgcg ttcaaaccag aggacaattg
    12241 aagagatagg gaagcgtgat gaagaggact gcgaaaggta gtgatttaga aatatgtagg
    12301 taaaagggga ttcataacag tcatatctat ttctcctatc ccagaatatt atcatgatat
    12361 ttgagagata gcacaagtac catccggtct ctgaggtagc tgtggcaaca tcattgtttt
    12421 tgtgttcaac ttaagtagga gtagtgccag cagcaaggcc atagctccgt ctgcaaagaa
    12481 ccgagtgtac aagcgaatac tacgaccagc attcatggca gtattgattt tagctataca
    12541 tactagtaac atatatttgc caggggatcg ggtcagaccc cgctgcagac agataacgat
    12601 ctactttctg tctcctggtc cgaggttgat tgcctgagca ataaccaagc atctcaatat
    12661 gacagaagga gcatttaatg gcattcagtt gacatgatat taataaggct ccagtatcag
    12721 agtatcagtt ttgttaacct acgtgttgct atcttacaac caaagcaatt cccaacgcat
    12781 accagggggc caacaaggtg ttaactcgat taactatcag gaagtgattc agcaagttaa
    12841 tgtggaagag catggataca caagacgatg ggtgattcca gacagccatc tctgggacaa
    12901 tatctccttg gatccctatc cccatctcat tgactcgcaa ggaagcggtg ttctcggaga
    12961 tgtcattgcc gcagcttaaa attagaaacc atgcgttaca ccgcgccggt gaccctatat
    13021 tcatcggggg tgcttcaatg ggctgcctag tctcgcattc ttgcatccca actactgcta
    13081 cctatcgagt attgccgtct ctttgcggac tagccatatc gagaacagcc aatcatatat
    13141 cgaacttccc cttcaaaatg tctagaccta tataggacta gcccagatgc taaaagagcc
    13201 taggtaatca ggcagtacct cgtggatcag gcctaagcct caagtcctaa cttgcggttc
    13261 ccgaatatga tacaacaccg cttaaaagaa gcgtttctgg cccccaaatg gctaccggga
    13321 tcattaaagg ccagatccag gatgagactt gacgggacat tgacgcggga ggattgcgcg
    13381 ccggaagatt ttcaggtggt atgatcgatg cctcggtagg aagggccgta gagattcagc
    13441 ctgcttatgt tgggggccaa acctgccagc atggcagcgg gcagagcgag taagcactag
    13501 ttgggggcca aacttgcaag cagggcagcg cgcacagaga gagagatata tagagtaagc
    13561 actagttggg cggtattaca cacgtgtcct gtgtataaca taaaacggta ttgtacatgt
    13621 aagcaaacac gtatgataca ttactcgact cggtattatt tggaccgcat acgaggctcc
    13681 gaccggtaga tgagggctta tctctatggc ctcctactag atacagaaaa atgtttcaca
    13741 aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aaaaaccaag acaaacaaac agccatggct
    13801 gtcatgacca gcgaagctcc actgcagcga ttgttgcagc acgtttagat ctgcttaaaa
    13861 ctcataaaat gcttgttatt accagtgtcc atgtgcagca acgttcctgc accaaccaca
    13921 ttcaaagagg agaaacaaag gaacatcatt acgtcaaggc aagtgaaatc ctgctgtcag
    13981 gcgcccactc taatcccgct gcattgccgc catctttgtg catctggacc aaatcgcctc
    14041 cgggacacag atgccacctg ccacatggaa tgatctacct gcggccacct gccgctgtga
    14101 tgtctgcact ccaggccaat gccggcggtg ctgccaaacc gtttcatact gaattgttga
    14161 cttcctatat actccaaagc tattaacttc aacatgtaca atagtcaatc ctaatccaga
    14221 atgaaccaac ctatctacgt tgaataataa cgtttcttaa ggaacatctg tttcagtagt
    14281 tctgggatta agcgaccggc tttcaggaat gttctttgga actataccgc aatccagttg
    14341 ttcctagtct atcttactta tgatcctgga tatatgtata tctcttatta gagcttctgg
    14401 gcctcaggaa accatggtta cccttgcaag gaagcactag gattgtgcag gggaatttca
    14461 caggagtaat agcaagaatc agtacaacgt catttccgga aactactgca aggcaagcaa
    14521 aacttggagc agaaacctcc tttcttacat catgcacgga catttagctg ggctacagct
    14581 cgagagtgca aaatctggta atatcagaag gtgtagatta gggcccctcc ttcacccaga
    14641 agttggctga tgtgatccga tcaacttctc tcttgacatc gtttgggagt gctactagtc
    14701 cgaattaatt ggctcaaaaa agggtggtgt attcagggat atacagaaga tactcctact
    14761 gagcaagcag catatcagcc acggcttctc caaaagcata cataggagcc tggtaatgac
    14821 ctgccagtgg caaaggaagc acactagcgt cgcaaactcg aaggttctga acacccttaa
    14881 cccgacactg ggtgtccacc accgtcccca tagcggccgt acctccattt tggaaaaaac
    14941 tactccccac aatctgcaca cgtcggtcta ggtctgcatt actggatgca ctggtgatgg
    15001 gctcatggcc cggcggcggt gtctcgccat cgataacctc ctttgcagaa tctgtttcca
    15061 taacgcgcaa ggcgactcgc ataccagcgc gtatcgcggc acgatctgtc tcagtgtcga
    15121 gatatctcgg gtccagtact ggatcagcag tgggatcagc actcgcgagc gtgacactac
    15181 ctcgactggt tggaagaagg agaaccacgg ggctgctgat gtggtttccg tccataggga
    15241 cccggaattc ggaaccacca ccggcgattg gtgcgtaggc taccatcact tccacattgc
    15301 cgcggggttc ttgtaggtaa gggtcttccg cgtcgatcct gtctttttgg gctgcctcga
    15361 tgagctctgc gtgcggtgta ggaaccgttg caacccattc tatggggttg ccgtgccgaa
    15421 actcgggctt gttaaagagt ggggagccaa gtgcataccc cttctccggg ttccgtagct
    15481 tccagaagaa ggttgccgag attttatcgt ggtaattttc tccaacaggt agatctgcga
    15541 tggtggggat gttgtgttgt gcgagatgct gctggggtcc aatgccggat aacatcagca
    15601 actgaggtgt tttgatagca ccgcacgtca cgagcacttc tctcgatgcc gtgtattgag
    15661 tcccatcggt cagtgtgata ccggtagccg tcttggagtc gtcgaaattc acccgtgcga
    15721 tgacggagtt cgtcagcact gtcgccttgg aaagatcgta ggccttgctg gctggttgtc
    15781 ggagagcatc cttccagttc tccgtgaatg gtccaaagcc aagaggactg ccgccgttgg
    15841 tatcaggatt gtattccaga cccgcagcca acattgcatt gcggatctgt tctcgcagcg
    15901 ggtaggtacg agccgcggcc gttgtcgaaa tcggcccact gaacccatac ttttcagggc
    15961 taccggtcgg atcgtggtga gtctgcgcca tcttgaaaaa cttaagcata ttcgcatagt
    16021 tccaccgctc gtctcccact gccttcgccc aggagtcata gtcgactgag tgacctcgag
    16081 tccacagacc gtagttgatg ccactagagc ccgacagcaa tttgcccacg taattgggaa
    16141 cagagcggtt gcccagtcct ggctgcttgg ctgtcatcag gttgtattcc cattcagtgc
    16201 catggagatg cggtgcagca acaggactca tgatcttgtc gttgtagtct tcgggaccag
    16261 cctcgacgac cagtacgctg tgtcccgcct gggagaggcg acttgcgaga acgcatccca
    16321 cggtaccacc tccacagata acatattcgt aggtcttgct catcatgtca attggttcga
    16381 atgtcactct gtagaggaat agacaaaagt atattgtttt atcgtgtgga atgagcgctg
    16441 tgaatgacct ctcacttgag acaaagtaag attttatatc ttcattgagt ctaatgtaac
    16501 agctggcggg gttctcatgc cacccgaact agcgaaatca tcgaaggact atgagggaat
    16561 tacaagatcc ctgtcaaaat ttttgggctt acttgcactt ttcgccagcc tcatgtcacg
    16621 taaccatatg gcccccaaga agatccacgg ccgcgcatga ttgtgattgg cgtagctacg
    16681 tgtactgtgg cgcaagtctc ccgaggggag ttccaatcca catcatttat ttcccctcct
    16741 gataagcgct aaggaatata tatttcaact agtaaaaaag tttcacggca gattcctcta
    16801 tcttgctggc tccctccacc ctgtcggtcc ccttttgaga tccgtccgca aaaccgccgg
    16861 tttgcatcta ctttaagtac aacaacttta taggcgaaag gagccgcgcc cccccgcccc
    16921 cgtccacaaa ggttaataac aattcaaata agagcattgt caatacgagt atcgtgatat
    16981 agtgggaccc gcccccgtca gaggacattt gtcacaatca tttctccttg gcccccacca
    17041 acgtgattaa tttcaggcat tttggccccc cttcttgtgc ataagtatta aacatacaca
    17101 gaattaaatg agaaaggatt cttgcaagat cacagccggc atttactggc tagcgtaact
    17161 tttagagttc aggttccccc agcccgccag gcaacctgcc tcaaaccgaa gtcctcgccg
    17221 acgtattgat attgcggcac catagacttt catgaggtct tggattttgt gctcctcgtt
    17281 ctgaagggga caacactccg cttttgtggt atacacctcg ataaagacca aaatgggatc
    17341 cacttcgtct ccaggatatg attccagtgc aactcgtgtg cctatcatta ttggagtttg
    17401 tgtacctatg gttgttctgg ccattctagc aaccgctctt cgcatctggg cacgggtcat
    17461 gaccaacgtc aaattgtggt gggatgattg gttatgcatc gtgggactcg tacgcctgcc
    17521 tccccctcaa ccctaataaa acatcttact cgttccacga gaagctaata gaaaggcttt
    17581 tcccgcacag ccatttgcaa tcctgccttc catcttcgac ttcgttcaaa tcaataatgg
    17641 cttcggacga ccgatggcaa cagtgccagc tgataaactg gttacataca gtctattcct
    17701 gtacattctg atgttgttct ataacctggg actagcattc ttcaagctgt cgtgcctggc
    17761 actgtatatt cggatgtttg gaattcatcg ttggatccgc tacatgagtt atgtcatcgg
    17821 tctgatggtc attgcctggg tcttggccaa tgaattggtc ctggctttcc gatgccatcc
    17881 aattgatctg gcctggaagg gaactgcaga acagcaggca aaattctgcg tcacgcagac
    17941 gaacatattc atcgcgcagt ccggtccgac aatattcttc gatctactta ttctcatcat
    18001 gcccattcga gtcgtctggg gtctgcattt gcaatcggca caaaagcttg gtgccatcct
    18061 tgttttttct ttgggattgc tggttaccgt cattagtatg atccgcctcg cagatacact
    18121 tcactcgaca gacacagact tgacctgtac gttctttagc ttcatgagac ttagatgcgc
    18181 cagtgaaaga atctgacatt tgatgacaga cggatacgtc gaattaggca tgtggtctgc
    18241 ggtcgagccc gtgactggct tgatttgctg ttccctcatg acttatggcc catttatcaa
    18301 gaaacttcgc caagctggca aaggatacat tcgaggcaaa tccagccacc atagacagtc
    18361 gcactcttca aattcttttg ccactcaaaa taaactcaca ggtcatcgat ccgcggagta
    18421 tgatcagtct gacctcgaat tgaccttttg ctcattcagc aatgaggccc ccgtcgtggg
    18481 taaggccgat acctttggaa aaatacatga cggtgcgata aacatcaccc acgagttcca
    18541 agttcgacga gactaagctg ttcgcttgga aagcccccaa gcgctggagg acggcatatc
    18601 tccagatact caatttaatt attattatta cctttcaaag attattgagc cgttactcag
    18661 ttcacccttt tacaccgaca tccatgctgg aaatgacgtt cctctatgta agcttccctt
    18721 atgtaagcgt gccactccaa gcgtggtaga tcaagcacgt tgttttcacc ttcgaattcc
    18781 ggaaagctca gttcccatac gcatgtgtat ccacgggaag aatgaacagg accaagatat
    18841 ttgttgcatt agagcactat caacgtgtag ggaccgtata tggttccaag ttgttttaaa
    18901 acgggatgca ctgaatatgg gaatgtggag ttggcggcgc cggtggagag atgggctgaa
    18961 tagcgtctct ggaaattccc gggtgtaaaa tccacaatca atgagtgaac gaaagttgag
    19021 tcactccaac caatcacatc tcacagtctt tcttgggtac ccgagtggtt cagtgcacca
    19081 accaagcccc tcatcactac tagtggggac attgatttcc gcccccgtgc aggtaaacgt
    19141 tggagcgatc aggcaatcac agatgaatgg aggccaaagc tgcgattctg caagggcgac
    19201 gtacgaatca tgcacctcac gtggaacaca tggtcctgtc tctgtactag ctgtaaacct
    19261 atgagtggag tctttctttt ggcggttggg ggcgataaag ccccggagcc ttacccgtgg
    19321 ccgtggagac gacttctcat tgagtacgta tcgccccagt tgacgttgac ttaatttaac
    19381 ggtgtatttt tcgtctttct tatcgcggaa tttgatccag aaagttattt gttttcttac
    19441 ggagtgcatc caaagtgtaa gcgctagcac tggtgtaatc tgctgtttct gtaaaacagt
    19501 attgttagtt aagttacaag caaaggctag cgccaacact tttggtgcaa acctccacac
    19561 gcccaaggta tttatcttga gggctttcaa tctcctatgg atatagctag gtggcgctcg
    19621 gccggaacgg aattgagcaa atcagccccc atgtttgtgt gataacggcc cccatactga
    19681 agcggctcac gcagattagc cgacctgatc tataatctca cctatttcta ttaggctaga
    19741 ccgaacggtt gggcttcatg ccccgataga gagtaatacg acccaatcag ggaatctact
    19801 atagaaaatg tgcccacaag cctccatggt tcaaggtctt gaaaaaagaa tatctacagc
    19861 caattgatcc ttagtccctc atcagatttg tacaaaccga ctttggctct ttgggttacg
    19921 ataaaacaag ttcaatagtc tctgaacact tataaaagac tctgttgagt catcaatcaa
    19981 gatcgttccc catggcaatc atggaacagc cagcactggt tatatttggc cctcagattt
    20041 cttggcccag caattcaagt gcagagcgca tccggcgtga tctcgtccag gagccttctc
    20101 tcgcaccatt tgcggatgct attagaaaga ttcctgagct ctgggcttca ctggtcgaga
    20161 ttgaaccacg acttcgagaa acacagggaa gacggaactt ggaacagctt cgggactggg
    20221 tcgagatagg atccctacct aggagagaca gtccggacga aatactacca aatgggtttg
    20281 caactccgtt cacggtcatt gcccagtcca ttgaatactg gcgatgcttc ccacgtggcg
    20341 gcttgcagtg gcttcactca agatcagaag ctggtcctgc cctggagggg atgtgtactg
    20401 ggtttttaac agcaatcgcg gcagcaacct cgaaagattc gacagagttt tttaccatgg
    20461 cggcaatcgc tgttcgtttg gcagcctgca tcggcacctt cgtcgaccta aacggaaaca
    20521 cttcggatgg cacaggagaa gcaagagcat tggtggtcag atggagttcg cccatccagg
    20581 agtcgtgtct tctgagaata ctggaagaac agccgaatgt aagttctaca attcttccga
    20641 gtgccttaag tcaaggcttt ttcatcacag aaagacagga attatgagga tggaagaagg
    20701 agggaggggt tccagtctcc gaggagtgtt cgggttatcg caatccagca tactgatcaa
    20761 aaaagaatta ctccctcact ccgttctttc cttcacactt cggctgatcc tctcgatgcc
    20821 tagagtcaga gaaaatgtga ttactaactc aatataggct tatgtttcgg tactgaagga
    20881 cgagacaagc cgcactatca cggtcccggc atccgaaatt ccaagtaccg cggaaaaact
    20941 tttgatgaac gggttgcggg tacatgcgct ggagctaaaa gggaggtttc accacgcaag
    21001 caatgaagat attgcaaata agctccttca gatgtgccaa ttgaacgccg atctgcattt
    21061 tcctgatgcc caaggccttc tgacaaccct tcgacggaat tctgacggta gacgtctttc
    21121 taaaggtccg ctacatatca ttgccatcag atccctacta ttggaccagg tggactggct
    21181 ctccacaatg acctctgctt tggagtcagc tgtcattaag gacaaacccc caaaaatatt
    21241 ggtatttggg tcggtcaacg tggttccaca ttgcttgatt cagagaagtg gagctcgtgt
    21301 ctgcgtctct aatgacatga ttcaacctct ttctaacatc acgactaccg tcaaagactt
    21361 cgttcccgag cccgatatga ccaaacctgg ggttaagtct cttcctgacg ctccagggtg
    21421 tgacaatcat gacaactcga tcgccatagt cggcatggct tgtcgatttc cgggtgcaga
    21481 ctcggcggag gagttctggg aattgctcga gtgtggaaaa tcaatgcttt ccgtcttgcc
    21541 agaaagcagg tttccaacca aaggtctacg aagatctgca gacgataccg tcttttgggg
    21601 gaacttcatt caagaccccg accaatttga caatcgtttc ttccaaatat cgagccggga
    21661 ggcagcttcc atggatccac agcagcgttt gattctacag gtcgcttacc aagctctgga
    21721 gtcatctggc tactttgatg gccaacggaa acctacccat accaacattg gatgctatct
    21781 tggagtggga tcggttgatt acgaagccaa catctactcc catcagccca attcatattc
    21841 tgctttaggg tcattgaaag ccttcgtcag tgggagagtc tctcactatt ttggttggac
    21901 cggtccgtcg attacatacg acacagcatg ttcatcatcg gtcgtagctt tgcactctgc
    21961 ctgtaaggcg cttctcagcg gcgaatgcac aagtgccctg tccggcggtg ttaatgtgat
    22021 aacgaatcca gctctgtatc aaaatctccg tgctgcgtct ttcctcagtc caactggtgc
    22081 gactaaagca tttgatgcag ctgctgatgg ctacagtcgg ggagagggat gcggtctttt
    22141 tgttcttaaa agactagaaa acgcattggc tgacggagac caagtacttg gggtcatcgc
    22201 tgcctccgcc gtaaaccaaa cacagcgaga gtacggaacg tcaataacag cgccggtgtc
    22261 caagtctcag caatccctct accggcatgt tctcagccag gccggcctag agccatcgga
    22321 tgtgacgtac atcgaggccc atggaacggg taccccaagg ggagacccga ttgaatgcga
    22381 aagtattcga actgtctttg ggagtactaa tacaggacgc cagcaaacgc tctatttcgg
    22441 atctgtgaaa ggaaacattg gacacctgga ggcaggctca ggtgctgcgg cacttttcaa
    22501 gtcagtcctt atgcttcaga agaaaaagat tccaaaacac atgaacttca acaaattgaa
    22561 tccccagata cctccattgg aaccggagaa gttggccatt cccacaaaga ctatttcgtg
    22621 ggatgccccg ttccgcgcca tttgcatcag caattatggc gcagctggaa gtaatggtgc
    22681 actcgttctg cgcgaggctc ccgagcccct gaaatcgacc tgcgcaagac ccactggaaa
    22741 tggccctttg cgatgtcaac tgatatccat cgctgctgat tcagctgaga gccttcaggc
    22801 ttactgcaat cagctattgc ggtaccttgc tgatgtaaat gagaggcatt ttcccgatgt
    22861 cgcctacaag ctggcccgca ttcaaaatcc agcacacaaa tatcgactgt catttgtcac
    22921 acgctccatc agtgagctgc ggtctttcct ttccgcacaa agtcatgtga caccgactcc
    22981 ttcattctct ggaacggtca agcccgttgt tctttgcttt ggtggccaat ccaagtccag
    23041 tgttggtatc aacaagcagc tatacgactc gatttcgcta ttccgccacc atctcgatcg
    23101 tgttgaagct gcctgccaag cgttggggaa aacaatctac ccgtttatat tttcgaaaga
    23161 agtcattcaa gactctgtta cccttcattg ttgcttattt gcctcgcagt atgcctgtgc
    23221 cagatcttgg attgatgcgg gaatcaaggt tgcgacagtc attggccaca gctttggcca
    23281 gattagcgct ctttgtgtct gcggtgtgct ttccttggaa gatgcagtga aatatgtcat
    23341 tgagcgagcg ttgctgttcg acattaattg gagtgcagaa aaaggtacca tgcttgctct
    23401 gaagggcgat actcagattg taacacgact ggtatccaca agtcaagtcg agatagcctg
    23461 ctacaatggt ccaagggatg tcgtggttgc aggatctata caagctattg agggctttca
    23521 atcccgagcc aaggctgctg ggatcgacgt ccgatgcctg gatgtagctc gtgcatttca
    23581 ttcaagtttg atggatccag ctttgccgca gcttcgaaga atcgcgaacg cacttacatt
    23641 ctatcggcca tatattccaa ttcagacttg cactcaaggt cacggccggg actcctttga
    23701 cccagaattt ctggtcgatc attcgcgcca accggtgttc tttcatgatg ccgttcaacg
    23761 aatagaatcc cagcttggac cgtgtacctg gattgaggca ggttcatctt ccttcggtac
    23821 cacattggcg tcgagaattg cgagtcaact aaactcattt atccctgtgg atattggcgg
    23881 ccccagccct gcagagtctt tggcaaatgc aacactaaag ctacaagctc ttggctacaa
    23941 tgtgcagttc tgggcatatc accgcagcca acgagatgcc tttagggtct tcaacgttcc
    24001 tccataccag ttcgccaaat cgaaacattg gctagaattc aaagagttta acagccttgc
    24061 aaaggagtca agtcatactg atgacaacga tcaacattcc aaattgcttc tgttcgtcca
    24121 gtcgagagat agggagaaag gaattgctga gttcaaagtc aacgcgaatt ccgactattt
    24181 ccgggcttgt gtcagcggtc atgcagttct cggccattcc ctttgtcccg catcattgta
    24241 tctcgagctc gctgcccagg ccgcggtata tatatgcgaa aacgaatccc ccgtactgcc
    24301 acaggtggaa gacctccaga taagtgctcc tctagggctg aatccatccg caaccatcaa
    24361 gcttcttctt tccctgaagg agcccaaagt atggagattt tcgctcttga gtactactgg
    24421 agctgaggat atccatcacg cgtccgggac tattcaggtc cctgccaatg cagacttttt
    24481 ggtatcggaa tccagcctgt atgagcgctt aattggagca gatcgttgca actcaatcct
    24541 tcaggacgca tccataaaat caatcaatgg actcgtgtac aatgtgtttg gtgcggttgt
    24601 ggactataaa gacttttatc agggcgtcca acgcatctct gctaccaaat ctgaagcatc
    24661 cggagttgta tcccttccag tggccgctgc cggaatcatg caagattctg tatacgatcc
    24721 tctagcgctt gacaattttc ttcaagtttc tggaattcac atcaactgct ttcgtgattt
    24781 tggaagacaa gaagtttatg tctgtacgtc aattgggaag ctgaaagtgt accagtctct
    24841 agagaaggtg cgggatcaat cttggcttgt ttattccaat actaagcagg gtggacctgg
    24901 ggtattggaa agtgatatct tcgcattcaa taagaccacc ggatctctca tggtggctct
    24961 ttttggcgtt cgatttgcca aggtgtctgt aaactctctg accaaaactt tgtccgccct
    25021 caatcacgga aagcccgttc aacgattgaa ggattccacg ccgccatcga ctcctttgag
    25081 caatctaggt ctaggcacat caccaaaaac agagcttgac ggaaatgttc tgcttcgttt
    25141 acagcgtctt ctaagcagag tgacagattg tcccgtggaa gatattcttc aggtcaactc
    25201 tttggaagca ttgggaattg actctttgat gagatcagaa gtcacagccg aaattcgaca
    25261 ggaatttggc ctcgacatat cgaccgacac gttagccaag gcttcaaccc tattccattt
    25321 gaccacattg atatcatcgt cacaaaagtg gcctgttcaa attgttaata caccctcatc
    25381 gtccgaaagc cacacaactc tctcgatgcg tgactcaacc tcttccactc ttaaagatat
    25441 cctttcggcc attaccgata ttcctgtgga tgagattggc aatgacagca ctcttgaagc
    25501 acttggaata gattctctta tgagaaaaga ggtccaatct gagctccgga agaatctggg
    25561 ccgtgcagat attccagaaa atcttcatga atactctgtc acatcacttg ccgcatatct
    25621 cgccgaccag gattgtggta aaaggaatga cctttcgtgc ggtacgccgc cgggcagtgt
    25681 ttctcttgga aggcattgcg atattaaagc gctgggttct catacgcaat tgatggcccc
    25741 agaaatgata tcaggattgg aagagaggca ggaactcgtg aaaagaaatg atagaagcca
    25801 gctatttcag ctatcgagtc caccgaaacc tctttgttcc agcaccgttg ggggattcac
    25861 actaaaggac cttgctgcct cattcgaaga aatcaaagga gctttcgatc aactttcgga
    25921 tgaatctcag tttctcaatt tctacgctca ggtccatccc cgtcagatga aacttgccac
    25981 ggcctacgtc gtcgaagctt tcagaagtct gggctgtccc ctttcttcga tgtctccagg
    26041 ggagagcttg tcgctatcgc ccgtttccta tgagccacga catggaaacc tcatgaagca
    26101 gctatacaga ctgttacaag acgcagggct catttcactc gacaacttgg gagagtacaa
    26161 gcgaacatct aagcccgtgg actgcacttc ctccgccgat ctcctcgacg cgatcataca
    26221 agactttccc caacaccaat tagagcaccg tctcctgagt atcactggct ccaggcttgc
    26281 gtcctgtctg tctggcgagc tagatgctct cgatttgata tttggggatc ggacagccaa
    26341 ggacctggtt agcgatgtat atctcaaagc ccctgtgttt gtgacaggaa cgaagcttct
    26401 ctgcaaattc ctgctatcat gccttagaca aagaactcag cccatcagga ttctagaaat
    26461 cggagccggc actggaggaa ctaccgctga tgtggttcgc tgtcttatca gcagcaatat
    26521 tccattcgag tactgcttca ccgatctttc cccatcccta gtcgcagcag ccaggaaaaa
    26581 gttcaaatgg tgtcccaaca tggagttcaa tgtcctggat atcgaacaag aacctccatc
    26641 tgtaaatcag tacgatctgg ttgtatccac gaattgtatt catgcgacga ggaatctcac
    26701 tgcgacaacc aaaaatatcc acaaactgct caaagaagga ggcatcctct gtcttgtgga
    26761 actcacacgg aatttaccgt ggtttgattt agtttttgga ctacttgaag gatggtggct
    26821 attcaatgat ggtcgtcaac atgcgcttgc gcatgagctt ttctggaaag atagtttgag
    26881 acaagcaggc ttttcatata tcaattggac taccggcgac acgaaggagt cagagcagct
    26941 ccgcttgata ataagcgtga agatggatca tcaatacgac ctttccaagt gggaaactgg
    27001 tagcgagaag tgcacagggg acaattttga aatagtcact tcacgtcaac cattgtcagt
    27061 atattcaaca cctgatctac ttaaggaacc tgggcttagt gggtcagttg tgcttctaac
    27121 tggcggcaca ggtaatcttg gcacccacgt cctccaccag ctgattaatc gagcagacgt
    27181 ccgccgggtg atatgcttga atcgattgac aacaaatgat gatccaattc aacggcaacg
    27241 acgtgctctc agagataaag gtattgatct taaagaacga cagtgggaaa aaattgaagt
    27301 tctcgaagca aaatcaagcc acacggccct cggtttgcaa accgaacaat accagcgatt
    27361 acgagaccaa gtaacccata ttgtccacaa cgcgtggcca atgagcttca agcggtccct
    27421 gcacacattt gaacctcaat ttaaaacact gcaaaacctg ttgaagctct gccacgaagc
    27481 caagtacggt gcaagactct tattcatctc ctcgataggc gtagttggcc gccaccccaa
    27541 tacatttgcg aataagccag ttccggagga tccggtgagg gactgtcaaa gttcactcgg
    27601 attcggatac agccaggcga aatatcactg cgagcagatc ataaatcggg cgctagagca
    27661 agatacccgc ctcgaagctt cctacgtccg aattggacag ataacgggtt ctcaacactt
    27721 cggtttgtgg aatacagagg agcacgttcc ggctttactg agaacatcgc aaacaatagg
    27781 cgctctgccc caccttgatg gagtaagttc ttggcatagt ttgaattggc atttgtgaac
    27841 tgctacttac gatgacacag cttgcctcct ggctcccaat cgatattgcc gctgccaccg
    27901 tcagtgagct cctattggat acggctcatc ttcggatggt gtatcatgtc gaaaaccctg
    27961 ttcgtcagcc gtggtgtgag ctgcttggtt atctctctgc gcatttgagg ctgcctatca
    28021 ttccgtataa ggaatggctg agtcgaatgg agaccaatgg agactccgtg acagggtcac
    28081 ctaatccggc gaagaactta agggatttct tcaaaaatga ttttcttcat atgtcctgtg
    28141 ggtcagttgt gatgagtacg accagtacag cgtctgtctc tgcggctcta cgatcagccg
    28201 gtcccgtgag tccaggaact ctgttattgt atattgagca gtggaggagg actggctttc
    28261 tggggtgata gatatatgtc agctccacat ggcctctgca tcgacaagag ggttgcttgt
    28321 cagccgccgt ttcccgagaa caggtcaagc aatattaatg cccggtctcg gtattgggtg
    28381 aagtctgatt tggaagattt tcatctctgt aggagcggtt tctatgataa gaacctcggt
    28441 aaattaactc acttcaggcg aggttccata aacgtgaaca gataatatac catcgcgccg
    28501 tcatggcttt gctccaggtt ttaagtattt ggctaagaga aacctgatga gtggactcgg
    28561 caagtacaat tgttggacgt cactatattc tgttgtgata atctatagag acgcgactct
    28621 ttgaacattt gcttcgtggc cagcccgact catgggtacc tatagcagtt ggactgttaa
    28681 gggaggtaca gttaacttag aagccgtatt gctttaccac aatttcgccc tacgtaacgt
    28741 tatagctcga aggattgggg ccaaaattgg gggccaggct tatttagttc aggcggggtc
    28801 ataattgcta cagtatgtaa tgttgtagga tatgtataat ggttgtattc tttagtaggg
    28861 ttgtgggtta cgacgccgta ttacagatac gggtaaaccc atagcgcaag aaaagggcgt
    28921 atctggggcg tctctggatg acatgacaat accgcaagta cagatgattc aacatgtagc
    28981 aatttaagcg ggggaagatc gtcgtgggct cgtggtatat ttaggttcgt cagtatcccg
    29041 agcctcacag gcttttcact cacacctctg acaatctcca aattcgttcc gacaaaagtc
    29101 cggccaacgc tttgtacaaa taaagtgact ccaataagtg ccattgagat accatattgg
    29161 cttctgtacc tatatttgtc accttcgact cgcaacccat gtctgatttt gcgtctcccg
    29221 cctctggccc ctcttcttca tcttctttag tccccactat tgatatctcc ccatttcttc
    29281 taaatccaac tagcgaagca gcaaatgatg tatgccaggc tattcgtgtg gcgtgtttgc
    29341 acacaggctt cttccaggtt attggccatg gcgtgtctat gtctaccatg actagagcct
    29401 ttgaggcatc gcgtcgtttc tatgcgctgc ctctggagga aaagcagaag cttgatataa
    29461 cgaaacatct tggattccgc ggatatgatg ggataggaac tcagtcatac ggtggagata
    29521 ccttgcctga tctgaaagag gtaagtcttt acatgaactc actacctcca ttccattcgc
    29581 cttgtgtatt cacaaagaac acttgttgca gagttttttc attggccgcg atgtttctca
    29641 atcacataca gactatggcc gcatactcac aggcccaaat atctggcctt cttttcaggt
    29701 cctccccgca gtcgcattca aggagtctgt agaagcattg ttctcggccc tgatggaact
    29761 agcatgcaag atcctagaga tactagcgcg gactctacca tacggcgaag ggatcttcga
    29821 tcgttttaag cgcgatcctg ctacgcctat gcgtatgtta cactatccac ccacggaggg
    29881 gcaatggatg ccgctgcggt cgacgacgag agacagctcg gtgcttcggc gcacacggac
    29941 ttcggtgcaa ttactctctt gttacaagac caagtatctg gattgcaggt gcacgactcg
    30001 gatacaggta actgggtaga cgtaccacct cgtcaagatt ctatcgttgt caatatcggc
    30061 gatatgatca cgcgttggac cgcgggtgag tataagagca gcgtccatcg agttatcaat
    30121 cgttccagta cagataggta ctcaatcgcc tttttttttg atgggaatat tgactgtcca
    30181 cttgatcctc tcgatggcac aacagctcct ggtgagtcta ttacggttga gcaacatatg
    30241 gttgagtgta tacgttcatc gtatgcgagc aagtagattt atcatttgtg tgggcgcatc
    30301 tggataatcc gggttacaag gtataaatac ctggcaaaat gacaatttat ttgtcgcttg
    30361 tcctattggg tatataggga tacataaagt gtttgcgatg aatgacaccc tgaatcgtca
    30421 ttagatccca atgccataaa gcctccctta tcgatctgaa agaaaagaaa ctcaaccggc
    30481 tcattctggg aagcgaagga tgaaacaccg ttgatgggca agactgattc taatcgactt
    30541 gtaggagggg taacgatccc tccagtgtac atgttgatca ggaaattggg cacattcggt
    30601 caaagtccca cgtcaggacc aggagatttc agtacagttc aaatcaacct tcaaaatgag
    30661 atactgatct ctctatctaa aattttcaca caggactctg tcattattcc atgcttctac
    30721 aagggactgg gaaaggaaaa agaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaggaaatga
    30781 tcccgagggt taattgactc gtccgcctat ttctactttc ccttgcgtgc cttcacgatg
    30841 agcagcgaag gacctgtccc attgattgcg tctgtcctgt tcggaaggga tcataagatg
    30901 tcatcattcc tcttcaaacc ctcgggataa gcttttagat cgagacccgt aagtgcagaa
    30961 agtgaatcag agtctttgta tcattgtcta gtagctagca gcttagagta gtcaaagagt
    31021 aaatgcaatt attcaactag aataatctca tagtggaatg gataaagtat aagtattgta
    31081 atcactaaga atggcggtgg tcacatcatt ctctctctag ctctctgttt cgtttctctg
    31141 gcatgtatct cgagctatct ggtcattttc atagctgaca gatcataagc ccaaaaaggt
    31201 tgaaaatcat tctagttata ttaaatttaa acaagaatca ttattttatc ttcaaatcca
    31261 gtaaaatcta tatatattct atttatttta ctatttcatt tgttttgcta ctagttgata
    31321 ctaagatatt gtaaggaggt gaatccatac aaggtccccg ccttattccg tgtgtacctg
    31381 agtatatagg gctccctatc ggtcctcagg gaatctgcgg gtcatgatgg cctttggtct
    31441 tgcattaacg tttccctcta gaagagtccc ttactatatt aactatcaag tttactgttt
    31501 taatattaat aaataaagaa agaaggaagc tgattcatga tttcaatata tgactatcta
    31561 attaatatta caggactaaa tctccagtgc ttatattatt agctaagacc cctacctaat
    31621 aatccattga ctactcactg acgagaggag atgtagccaa gcccctggaa ttgcatatcc
    31681 agtaggacaa actacggagg ctactccgac cagggaagct ttatttcacg gggaatattt
    31741 gtacagggtg tagagagacg gtaacaacat attaattcaa gaactgctac agctatacaa
    31801 cataataata aacccagcag tcaagtaaca cgccttaggc gcaagcgtct atggccatcc
    31861 agtagcttct accaatccca tcgcttacgt gacaatccat cagagcacat agcggaaggc
    31921 tggctgctcg aaatccgtca aatcgaggaa ctcagtccca acaataacgt tctcgcggtc
    31981 gggatcagaa cttgcctgcc ggtcgcgttt cttattttcc ataatgttca ccagacgaat
    32041 taccaataag gtagccgctg ccagagcgta catgatggca acgagcaact tgccgtcgaa
    32101 gtactccggc gcttgattcg agcggaacgt ctgcggtccg atccagtttc cagcagcata
    32161 ggccaatatc tgaagaccat tcacagttgc cttcttggtg taacccagcg tattgttaga
    32221 tatcatcacc atgaccaaac accacgaggt cccggcagca ccgatacaat agtaacccac
    32281 caacaagccg gcttttgcgt gaaagggaag gacaatcatc aagatgccgc caaccatagg
    32341 tataaggata gcgatgatgg caaagagggt tcggtcaagt aatctgtccg acatgtacgt
    32401 caaccccagc ttgcaggaga tatcaacaag acccattggc atgttaagca tgagggacat
    32461 ccggctagag aagccgaaag agctgataat gagagaaccg aaggtagtga ttcctccatt
    32521 tggaatattc atcaagaatg aaaatagaac gtagaggtat gtgcgtggat cccggaatgc
    32581 ttcgaagaaa tgtgcccatt tccaagtacg gttcccaatg ccttgaaaat tgcctctgat
    32641 gcgatcaaca gcaatatgct tctcgcggtg gctcaggaat ttggcctgga tttgattgtt
    32701 aggcatgaac caaaaataaa gaaagccggt gagaacggta ggcaagccaa gcaccaggaa
    32761 gagtatcttc cacacaggaa tagatgcctc ctgcacacct gacagtccat acgcgattgc
    32821 cgcaatcagt atctgagcga caccgttgca agcaagccag aagcccatac gcttggcctg
    32881 ctcctcttgt ttataccaac aggaggtaaa caggacgaag gccggagtta ttgtcgcttc
    32941 gaacgcgccg aggaaaaagc gaacacagag cagtccagcg taactatcag ctgcgacatg
    33001 gcagagaagc acgacgcccc aaatcagaat attggctgaa gtatatttcc ctagcggaag
    33061 tcgacgtagc agataggtag tgggaaatct ataccaaaat tagcatggac ctagaaaagg
    33121 gaggtagaga gaatttaatg gtacatactc ccagaatatg tatccagcgt agaaaatgct
    33181 cgagacccag ctgtattgct gtgactcagg gtccaagtgt gcgtcctcgc ggattcccat
    33241 tagggaggca taattcaaag acgttttgtc ggcaaattgg atcaaataaa cccaacacag
    33301 caaaggcatc aggactcggt cgatcttgaa caacactttg cgggattctt caggggtata
    33361 ttcgatttcg ccatcaacca taaactgcag ggctgggtcg aagtctcgcg tctctccatg
    33421 cttgatctcg ccacgctgga cttcagtatc cgcttgctcc atatcatggt tgggtggaac
    33481 ttttaaaacg tctttttcgt tgggttgggt agtcatattg ctatgtcaca atcacttgat
    33541 ccatcatatt cggaaatcat cgatttgcgg agtcatacgc tccttaaatg ggtccttgca
    33601 cggacctgat aaggatgggg caaatggccc cggattttcc aaataccaaa gtttgttccg
    33661 gagatatgta cagcggttaa taccggtgac cgggcaataa tagtatttta gataagatac
    33721 gcgatctaat cagattttat accaattctg ccggcactta aacaccaaga aatcattatt
    33781 gcccgatggc cgctattagc cgccgtagat atgcaatttg cggggttggt ggagctccac
    33841 cgcctatggg tttcgtatct cttccgggct tctcctggaa tcttttcatc gataagtcac
    33901 aagaggccga aatacgaaga aagatttgcg taggttccca agccatgaaa gcctacgcaa
    33961 tcggctggag aattgtacca aggacgaacc gaccacctgg ttcagaattc cctacccctc
    34021 agccaccagt ccgtttcgcg ctcgactccc ggtatagttt aatgtatccc gtttttgtct
    34081 caccctaaaa cacctcattt tgttgtttct ctggtgaacg tagcagtcta gaaccaattg
    34141 tgatgaaggt tttaacgtga caaaacagaa cggagctggc tttcaggtat gtatagtgcc
    34201 cttttccatt ttgccctctt gttatagaat caacttattc agaaatcgga aattcatttg
    34261 gctatgtgga tcgatccttc cattatcaaa tctcccatga tgtacgctgt tttctggttt
    34321 acgccttaaa ctcaggtaca atgtacatcc caaatttcga aatcagaggt ctggaatggg
    34381 ggtggtcagt agctttcgta gaacaatcta attctattgc aagaatataa atccataact
    34441 taaaccagtg ttgacaacaa ataacggtgg gtgaagtagc ttgcgacttt gccagctact
    34501 cttctcgccg acatacgatt tgatggatac attcggccac atagcgcaca ttgccttcgt
    34561 tgagcccggc tatagagaat ctggagcttt cagccatgta aatatgatgg aattctgaat
    34621 tttaagggtg aataagcttg attctctcac gcaatctgaa agcctctgag gtttgactta
    34681 cttttcacgt aatgaactcg gtcgggtgtg agaccaagca cgcaaaacat gcctttctgc
    34741 tgtgttaatt tcttccaatc gcccggagta cctggtagag aattagttcc tgggatgaaa
    34801 gtgtgttgaa aagggtaaga atttgcgata cctaatgccg tcagttcacc gaataaccgc
    34861 ttcctcattc cagtaatgcg cgagctcatc gtcataagat cacgctgcca ctgagagaag
    34921 aggcctccat ctccgagaac cgtagcgacg ataccagcac caaatgctgg gggattagat
    34981 atatcgcagc ggatcaactg ggccaaattt gactcgacgt tcgtggcgat gctgtggttc
    35041 cgtgatacga aagcacatag tccggttctc tcgcccatga gaataagcga acgtgtgagt
    35101 gagagtagat actggaaggt aaagcacaga ttgacctgcg acccaactga gcctactggg
    35161 acaacaaagc gaacacatac catacattcc catgcttttg gcgaaggaaa tgcagacacc
    35221 catctgaaga ttgagctcct ccgcaaagta ccggattgcg taggcgtctt catcgtagtt
    35281 gtcagacgtc aatcccaagt acgcagcgtc aaaaagaggg aatagcgttc tctccttcat
    35341 gagagcgcca atctttctcc attgttctgg cgtaggatcc cagccacttg gattgtgtgc
    35401 actagcatga agaacaaaaa tcgacatcgg atctgcttcg gtcatcgctc gaaatagtga
    35461 ttgcatgtca acaccactac ttgaggcata gttgaattct cggactgaga agcctactga
    35521 ttcgaaaagc tgcctgtggt tggaccagct cggattggtg atgtatccag tttgatcaca
    35581 aatagatgtc cgcatgagca tcattcctgc catatgcagt gcaccagtac ccgataatgc
    35641 ttgacaggag gcgacctatt aggaagggat tgacatatta gtttcttgtg gcaatgataa
    35701 ggctctaaat tgtttacccg actctcccgt atagcggtag aatccatctt gaagaccaat
    35761 tccgtaacta attttcgaaa ttctggatga cccaggatcg gaaggtattc gtgttcgcaa
    35821 tctttgatag cttccttggc tgctttaact gctgggagta gttaaggaat tccttaatta
    35881 tctttgtatg tgccttggcc caagttcgct ttgtgagtgt ctggatcagc tttgtaatct
    35941 ttggtgagtt cgaatatcgc gtccggggcg tataggccac gtcttcaaag aatgtagaaa
    36001 atgacaacat tgcgcggaag aacaagtgag actagtcttg accagacaca aacaaacaac
    36061 tcggaattga tggggcaatc catgatcccc gtatgggcca cctgtcttga tggcgaatgt
    36121 gcagtggaca aatctatggt ggagctccac tcgccatcga tacagagagc aagcaccagc
    36181 actgatagat aaattgatca ctccgcgaaa tcctactaca tctctactca gagtgttctc
    36241 ggacaagaca aacattcttg aaatatcagc attcacaacg gcaatggttc cactaacgcc
    36301 caaattcggt gtatacacac cattagtgac cttctttacg gaagacaaat ctctcgatat
    36361 tgaaagtacc ttgacacatg ctaagcgcat ggctgaaggc gatgttgctg ggctagtcct
    36421 tcaaggaagt aacggagaag caccacatct ggatcacgaa gaacgcaaat acttggtgcg
    36481 cgcagtgcgc gaccatctca acgagttggg gtatgtgcag atacagctga ttgttggatg
    36541 cggcgcaccc agtgtccgag aaacattgac gcatattact gaagcaaaag aatctggcgc
    36601 cgactttgca ctggtgttgc ccccgtcata ttgggtctta gctatgagca ctgacgtaat
    36661 tgaagggttc ttcgacgatg tattttccct agtttccagt catttcagat tacttatcta
    36721 gattacctta cctgactgga tcacaggtag catctagctc tccacttcca gttctgatct
    36781 acaacttccc tggagtgact ggtggtatcg acataagttc agactcaacc atccggctcg
    36841 cccagtccaa ctccaatatt gttgggtgca agctcacttg cggaaatgtt ggaaagcttc
    36901 agcgtatatc atctacactt cctaccactt cctttgccgc atttggagga aagtcggact
    36961 tttttttgcc cgccctcgta gccgggtcca atggaatcat cgcagctctt gccaacatcg
    37021 cgccaaaagt gcatgtggaa ttgctgagaa gatatgagaa tggtgatatc aagggtgctc
    37081 aagagcttca atctttgctc agtcatgcag acggtgctct tgtcaaagtg ggcgttactg
    37141 gtgtcaaagc tattgtggca cattgtttca aatatggttc agggcaaggg cgaaagcccc
    37201 tgcgaaattc tactatcgcg acactgagcc cgaacattct ggagcccatt ctaagagtgg
    37261 ttgagcggga aaaaatgtgt aattagacaa tgtatttgaa ttagaaaggt cttgaatctg
    37321 cggtggtata gaagctctga atatcacatc aatgatgaag cctgcacatc tcggccacga
    37381 tcgcaatctt taaatctccg aagaatgccg tatggacggc ggaaaataaa gcagacagca
    37441 ggagacgtag ccatccttta gctcggcgtt ttaagcagat gacaaacaca atcgacaagc
    37501 aggtctgatg gcgctagtcg tgccattacg caagggaagc aggacgcgga gcaacttctc
    37561 tcggttcgaa tatcttggag aacaaactct tcgaagaata ggaaggaaaa agagaggaaa
    37621 agagaaagaa ataaagaaag gtcggacagg gcaacctgcg ctggcctgga aacattctac
    37681 aggggaatct cagagaaagt cccgtgcgca tttcctacag ggagttctcc atcagaattc
    37741 aatttcaagt aaaataatat caagttttaa catgaactac tagctaagag gattcgcttt
    37801 gttgccgact attcgcactc cagaatgaca gccccgcctc ttgacgagca atgccataga
    37861 tagcggagct atctaaattc tcgccagcat actcgcgtgc agtatttagc cgtttggaag
    37921 ccgtttcaag cgtgtgtagg cggacattat gactgtcggc aatagataga gcgtgcttca
    37981 tgtccttgca tgcaagagca gccgcaaacc caggcgccgt gtccaaagga ggtgcataag
    38041 ctccactcgt gattcgtttg ctgtaacttt gcaatacgga cccgaacata tttccaataa
    38101 atttttccat ctgctgagtg ctgattcctg ctacctcggc aaagacctgt gcttcagcaa
    38161 tgacctccat gaagctgatg acaaggatgt tcctgcatag acgaaaagag ttaatacatg
    38221 aaaaataacc aaatgaggaa gaagatgatt tatttaccct gagattttga ggagacttga
    38281 tttgcgcacg tcttctccca tttcaataat gctgcgtccc ataacattca tgataagagg
    38341 tctgattgtt tccactactg taacaggacc agcaacagcg aatatgagct ttccagcggc
    38401 tgcgactggg cttgcgccaa acactggtgc tgcaatgaat gtcgcaccat gctctttgag
    38461 acgtttcgct gcccactcag atgtgtctgg gtgaatagta gatgtgtcaa cgaagatttt
    38521 accctttaga gagttcccca tggtggaagc tctctccaat agatcgatca acacatcatc
    38581 ggtggagatc ttcaagttgt tagtagttct ctcaaaccga atatcttgga ggtgattgaa
    38641 caacagcggc acctaccatt gtgaaaatta cattggattt ctgaactagt gcatcgaatt
    38701 cttcaggcac agcccctgca tcgcgaagaa tatctccctt ggagattgtt ctgttgctgt
    38761 atcgaagcgg aggcaagttc tttgcttgaa ggtacctctg gaggttcaat gacatgccaa
    38821 ggcccataga tccaaggccg tactgtcatt tcagtgagtg agtcaagtgt acaagtggga
    38881 tctggtgttc aaagttcaaa cctacccagc caacttgtgg gatagatggg ctcatccttg
    38941 tttgcggata gcgaatattc tccccaaaga aagttttgag tatagtgtac ggtacatgca
    39001 ccaagctcat gtggctgtct taaatgggcg ctggctggag ggcgctgata gctaaagtgg
    39061 agcataagag gtcttggcca agtggagctc cacattttcc acttactctg aatcacaggt
    39121 agcggcatcg ggaatttctc tcagcaccgc caacatcgac ggcccgatgc tccacacaag
    39181 tcgctgctgg cagaaaacct tgactagatc cgcaaacaac aactgccctt gctctagtaa
    39241 agtagaaaag acttcacggt ctgtagacca caagcgtgga tctcgagcat ctcggtcacg
    39301 tctcgtcgcc ggagagtaca gcaaggtggc ttcaatgagg gcgttgaaga tcagcataca
    39361 tggttcggat gtccgtggga gttcgttgaa tgtgttcaaa tggtcacgaa tttcagtggt
    39421 tgcacacctg agcgctcccc agatacacag aaggaccccg tagctggtaa ctgtgaccca
    39481 gggcgcctca taagaaacat tttgcgaatc atcgctaata tgctggcgag ggctgcagaa
    39541 agctcactga gtaaagctaa tacgccttcg ttgctgccaa gacgaggggc caacaaaggt
    39601 gcagatcgtc gaaccgcgac aaagttacct ctcataagat gggtcgaggc agccaggccg
    39661 gcaatcaagc tattgtcaac gatgcccccg atcagcagct ggtcaggtcg acacaaattg
    39721 acctggaggg atacaataaa tagcgagttt gttctccatt gaaaagactg ggggctgtca
    39781 ctcgctgtag ccgcgtcttt cacgatcttc ccaatattac gtattgccat ataaacactc
    39841 ttggtctgac tttgagtcag aatgtggaac gggttgggat cagaatagct gggtggcatt
    39901 tggtagtaac accgtgtgaa gtcccgcacc aaggtatcga gattcgccag tacgcagaac
    39961 gctgcgaacg gagatgcttc tagggcagca gataactcgg taccgggagc ttcagtcatg
    40021 acttgctgcg ttgccatcgt caaagatgct gctgctaatc cgcgaggcct ttgaagcaga
    40081 tcgttggtga atgaaaaagc agagacaccg aaatattcgc caaacctccg aatccatatt
    40141 tcagggtctt tggcctccca cagtttggtg gggaaaggga gctcccatcc aagttccatt
    40201 gaagacatta gtggcctaga attgcaaggt acaaataggt gtgagtccag gaaaaataac
    40261 gtatatagcg ccactcgcgt ggactcggca gctatatagg aggtccatcg agtataaagt
    40321 gttcgcgatt cgtctccgcg tggataaccg atgtcataca gccaggattg tgactctggc
    40381 atggcaacct cttgttgaga gagtccgacc tcgcgtacag cctagaattc aatcagtttg
    40441 gcagcacgga agaaaagcaa gaagattcgg gaccaacatc aacaatctgc cgtagcatct
    40501 ctcgtgctgt ccggaacagg gatgcctccc ctcctgcgta gaccccatag atcatgtaaa
    40561 gtatccaggc ttgcatcacc cagggtttcc gtatttcccc acattgattg gagacctatt
    40621 ttgacattta ttagcatcca agcacctaaa gccctaagag gatgatgtcc catgtaccat
    40681 atttcgaagt tcctgttgtc cactttgcca cgtggtacga cgccagtgta cacaagcttg
    40741 cgcttcttca tcattgcata tggtcgtcga acataggcta cctatcacgg ctacagcttt
    40801 gagcaatagc tttggtgccg ataatattgt aaatgtgggc cgatgtaaca agggtagaga
    40861 agggtggaag tgatcaaaat agtctttgac atatccttct aggtcatagt ggctcctatt
    40921 agtgagtctg tgatacttag agaagtcttc ttgcgcgcat gagatcaatc ttgctaggga
    40981 aaggcataca tcggggacgg caatatgtta tctcgagaaa gactagtagc aaaggagcta
    41041 tgtccctccc aaaagtgatc accaggcata acattcgcgg ccggcgcctc ggttgaagtt
    41101 aagacatcgg tcgcagttga aagcggtggc atgtcagcag ttccctggta gctctgctgc
    41161 ggactcgttt ctggacgaga tatatgatca ttcgatgctt caacgcggca acgaccccgg
    41221 tgccttttga acacgtcgct ggggtttggt cagtgatatt ggaacagaga agttggcgca
    41281 agtgtgagca agaccttcta gtaaaaacag cgtgacagcc atcacattca aaatcatgac
    41341 tcgtggcacg atcatggcct aagtgtacaa cagtcagtac cgtgagatcc tgtttgctcg
    41401 gttttaggcc gacgacttac gagcgcgctt atgtcttcgc aaattctcct gtatacacga
    41461 attctccgta ataagttttg ggttgttgga agaagaaact gatctgttac ttacatttct
    41521 ggtgaaagtt ttcgtacatt cgtcgcaagg gtatgggcga gaggaatcgt gaatcaggct
    41581 ctcttcgggg gctttgcagg gtcagcagcc attgggactg tttcaaacat ccaattgcca
    41641 aagaatggat ttcttcgctg atatcatgtg tactcagcag gatatgtcgg ttattgatgt
    41701 gatgtagaga agatggagac tcaactaaac tagcctcacg caggtggtat gtaacccctc
    41761 ttctgtacca catgaccatt accagctaac aggacagagt gggtcgtgag atagataact
    41821 ggtttaaatt gctatcttct cgtccgtccc cgggaggcac aattagcgcg attacgagcg
    41881 tattgtaacc gcgctttcgt attggccatg ctgctgtaag cgctctctaa tcaattaatc
    41941 cgaatcagaa ctatggcatg cactcaaaca tttctctttc acacatagcg ctttacctcc
    42001 acactttcta cgaccaggtc ttgaccggta cccgttgacc tcttttaccc atctgtctcc
    42061 tatacgggca ccatacgcaa gtttgctgcc tatccagccg aatccgctgg tgatttctag
    42121 gctcgatttg ctggtttagc ttagacctcg gcaggagtca cgactctccc ggtttgattc
    42181 gactcggaac cgccaggact caggttccga ttctaaggtg ttgtaaacga gatccgacta
    42241 ataacggctt ttggagtcgg acctgcgagg ctcgatttgg acctcagatt cctcaaacag
    42301 tgcaaacata aaattccaag aattacgcgt gtttttataa tgtattggag tgtgttttat
    42361 agaaaatgct taagcttatt aggtactaat ataaggaaag ataaagaaat ctagataaaa
    42421 tcagcatttc taattagcca gaccgtgaaa ctttaactct tagcttaaaa aatgtatttg
    42481 tatttagtgc agaaatatag taggaattcc atcatggaga ttactatata tcttcatctc
    42541 aaaatatcag atcccgacaa ctgccgatga ctactactac cagtaaagtt ttttgaaatt
    42601 tcaccactta aacgaatatc acttggtata tcttatgata ttgccgtaaa tacttctcta
    42661 taacgcgtga cggaacatat attacgtata attagtaaca ggtttattca actgcaaaag
    42721 gcaattcttg gcaaaaaata tacaattcaa gggtcttaag gttcgcacct gagtcgaacc
    42781 tgatagagtc gcgatctgag tcacgctcca aaacttaaaa tctgagaatc tcaggattag
    42841 gttcgaggtt ccgacctctg gaacctgagt cggaccatgc cgaggtctaa tttggccgag
    42901 gtcgtggtgg tggtgataat ggtggtgact gcaagtaaaa agagttcttg gtatagcctc
    42961 tcgcgaaaag ctaattggcc ctcagtcggc tactgatact actgctgctg cttgtagatt
    43021 tattgactga gataagcatt aacaatagct gcaacagaaa ggaaggcgag ccgtgggaac
    43081 cacgtgcgat tagtcttccg atggacatca taagcagccc gatactgact cgttatatca
    43141 acactaccca tataatggtt ctagacgttg ccagcgatac gaatctctaa ttactttttg
    43201 atatcagtac cgaaagggga acgtgcaata gctgtattgg ttgaggttgg cgctggccgc
    43261 tttcactcaa tcggtacaga gatacggcga atggatagag gatagaagta acactatatt
    43321 gttatcctgc catgcgtgac agagaacgct gttagctgca tacgcaaata attgtcccca
    43381 gggtgtgaag ggctgtagta gaatcgattc agttgtacta ggccaacatg ctgttttaca
    43441 gccatcttga ggaaagaaag aagaacagac aggagtcggt cgtggtcctt agagaggaag
    43501 aagtgccgga actgacatgc ctgccttcat atcgctcggt ctcctttgac cagttcgctc
    43561 aaaatcaccc actctatcta gacactgtat cccactgatt tccagcgcca cagaaagcct
    43621 ataaaggtct caaagaacac gacggaaaag aagccccgac ctacaccacg acgaaggatt
    43681 agggagcccc gactgctaaa cttgcctacg ataggagacc taggtaatag tagagcgccc
    43741 gaaaaagcac aagtacttat agagcaaaat actaccttgg ttaactagct taacgaatat
    43801 aaaacggcga ataggcctac ttattcgggc tatcgtgaat aggtcactat atacgcctac
    43861 ctctacgccc gctcctacgc ctacctaggc ggcgccggcg ataataacaa cgtaaggctt
    43921 agcaaactta actccattgc gatggattag cactggccat cttgcaaaat tacattgttc
    43981 tcgaattttc tttgactagc agtgccccaa cagctaaatg gggcacacgg cctgaactaa
    44041 tgagctgtat atccgacttg ggtacattga gggcaatttt caaaagtagc cctgggagct
    44101 ttcttgagtt tggagctaat ctagtcgatc agcttgcaat tggctttggt taataacgaa
    44161 atacactacc tcctgcttgg catctcatat aataatgtcc acatacaaag ccttagaaac
    44221 cggcttttcc ttcttcggaa ttttagtagc ttttatgtcg ttatcctagc ttaaaagttt
    44281 agcgttgacg tcaatcattc cgaaatccag tttcattctg gacgaatccg agaagccttg
    44341 attgagccct gacactagta catgtattca cagtcttaaa cttgctccgc cagagtccga
    44401 ttcgcagcca cgctgccatt agcaactggt atgaatgcgg gcatgacgac cgactcgtcc
    44461 ctttttctgc tgaccccatc ttcaagggct ccatagccac ctccaccggg tgtctcgatc
    44521 acgaaccgat cgccatgttg aactcggatc gaatttttac cgccgacgtt gatacagcga
    44581 ccatccttgg tgatccatgt attcttcccg cgctgaccgt cttctccacc cgccattcca
    44641 taaggtgcaa agctccgtcg ttccgaaaga atcgacacag acatggggag ccttagctca
    44701 atatccctga taactccgtc accacctggg tatatacccg caccaccact tccgctacgg
    44761 aaactgaaac gacgcaggat aactgggtat cttcgttcaa gagattcagg gtcagttatc
    44821 cgcgtgttag tcatgttggt gtgcacacca tctgttccag cccaactagg gcctccgccg
    44881 ctgccaccgg cgatagtctc ataatatcca aatccatttc cgccgtcgtt gccgaaggtc
    44941 aggttattca tgcatccttg gcttgcggcg catactctga agctcttgaa aatgacatct
    45001 acgatgcgtt gcgacgtcaa cacattgccg gcgcagacag cggcttcaga atctggacac
    45061 aggagcgatc cgttcggaac gattatttgg accggcttga tacacccatg gttgagcgga
    45121 atatcagaat tgaccatgca gcgcagtgcg aaaatgaccg ctgaattgca gattgcaatc
    45181 ggagcattcc agttccctgt catcaactcg gattagtttt aaattaagct gacagttata
    45241 gagcataatt accgtatacc tctgggccag tgcccgtgaa gtcgaaaatg gcggacccat
    45301 cggtaggatt gatcgtcact ttcagtttga ttggggtgcc atcatccatg tagtccacag
    45361 cagatatgtc ttctcctctg cgctcatgtg cgagacgctt caaaagagtg cgcacggcta
    45421 gctcagccgc ctcttggatt gcacgcatgt aaacctattg cgaattagct acacatcttc
    45481 cttcacgcac actgtgctta atatatacct gaacagtggg aagagaatac tcttcgatga
    45541 gacgttgcat gagttgagta ccacagtgat ttgcggccac ttgggccttg aggtcagtaa
    45601 cattgtcttg gtatcgtcgg gacccgctgc tgcctgggaa acgtgctggc tccacacata
    45661 gaacgcgatg aagctcatcc tcatcgaagt gaccagcacg aaccagcaga tgagagttga
    45721 agatagcacc ttcttccgag aggagctttg acgttggcgg catcgagccg gggagtatcc
    45781 caccaaccta ccggaaacaa tgagtggagg agataccaaa attcatgatt gaaagtcact
    45841 cacatcagca tgatggccgc gcgaagcagc ccagaatata atattcctcc cggcagcgtc
    45901 gaagaccgga gtgataaccg ttaagtcggg gagatgaaca cccccatagg cttactgaaa
    45961 gttagagaga ttttgacgtc ggcttgtgac caagaaaagc tggagcacgt acctggagta
    46021 tttgaaagta acacatcccc atcttgcagc tttccacgcc actcagtaat ctgcgatttt
    46081 actgcaaagg ccatactccc aatcatggcc ggtacatgag gggcgttggc aactaattcc
    46141 ccttctggcg tgaagatcgc acaagtgaaa tccagtggat ccttgatgtt cgcgctggta
    46201 ctgacattct gcaaaacgcg gcccatttgc tccgctactc ccatgaaccg atgtcggaaa
    46261 atggaaagct gaatggggtc aattgtttct gagctagtcg acttgggggc tggcggatct
    46321 atgtcaagga ttaaaagatc tcgagcgatg gtcgcttttg aatctggact cacgacgacc
    46381 gtctgcgttt tgtcaataat catagcgggc ccttcaatct cagttccctc cgaaagagta
    46441 ttaaggtgat agacaggcgt gttgacccaa cctagcgaac tgaaacgcgt ggaaaccctg
    46501 gagctgggcg tggctgcagc tgtagcagac gtggaacttg agagagactt gacctggaga
    46561 tatgaagagt cttccgggga aacgctgcat ccaattgctc ggacacgaat ggtgtccaca
    46621 taaacgacac ggttcacagg agtgaatccg aattgctgat gatgcgcttt gacgaatgct
    46681 tgtttcgcgt cactatcagg actctcccag ggtatcatga tggaggtttc gctgccatca
    46741 tatctcatgt tcaagaatcg acaagcccgg atgctgctga atgattccat agtcttgctg
    46801 catcgggcat agtcgacgag gctgtccagg gaatcattga taacatcaat ggcagaccct
    46861 tcaaaggctt tcgcgcagac tcgttcctct tcatgtacaa cttctgctag tccgatcccg
    46921 taggcagaca agatagagga atacttgtga atgagcacgc gtttgatacc aaggtcgctg
    46981 gcaatggcac aagcgtgctg gccacccgcg cccccaaatg aggcaagatg atgtttcgca
    47041 acatcatggc ccttctccag ggtcaaactc cgaatgggtc cacacattgc agaatttgcg
    47101 acctgtagga agctttttaa ataatactta ttagcgaatg aaacaatgag atatgattgt
    47161 gggtatcact tacccatctg caacctctgc ccatgtaagt gacatgccag tctccttgtt
    47221 tataacctgg gtcagctcct tgaatttagt gagaacgatg tctttgtcta atggctcgtc
    47281 ttcattaaca ccaaagacag atggaaattc ttcagggatc aaacggccga gcgcgagatt
    47341 tgcatctgtg acggtcagtg gacccccttt ccggtaacaa gcaggaccag gattggaaga
    47401 ggcgctctcg ggtccgaccg acatgagccc attcctccag gttaagatac taccgccgcc
    47461 agcggcaatt gtattgacat tcagctgtgg agcgtggata gtgatcccag cagttattgt
    47521 ctcgaagata tgatccagtt cgccgtcata tcgactaaca tcagtgctag ttcctcccat
    47581 atcaaaacca atcaccggag ctcgagtttc agtatcgaag catgttcgag aaaagccaat
    47641 aacgcctcca gctggccctg agaggataga gtgaagccct gaaaggctag acgaaggcac
    47701 caggcctccg tctgattgca tgaattctag tcgcgtccga gaattaccaa tattggggaa
    47761 gcttctggag aatctttcaa gatattgttt gatactcggt gccaaatatg cgtcaactac
    47821 cgtggagtta ccacggggga cgagctttgg tcttgaagat atctcatgcg agagtgatac
    47881 attttcaaac ccaatttcga gtgccatatc tctgatttct agttcgtgct ttgaaaagct
    47941 gtacgagtgc atcaggcaca ctgccaggga gcgaaaccct tcttcgtaga tactttggag
    48001 ttgaactttt gtgctggccg tatccagggg ctggagtact tgaattatct ctcctgatgc
    48061 tgcaatgacg gaatccacag gctctggaga ggacaaatga atattgcgga gatctgagtc
    48121 gctgcagttt tgcacagtca ctcgctctcg aacttcaaag gtttttgaat acaagggtat
    48181 cggccgccgg attgtcaagt caaacatatg gggccggctc tgagttctga tttgaagaac
    48241 atccttgaag ccttcagtaa tcagtaaggc tgtcttctct ccttttctct cgagtaacgc
    48301 atttgttgca actgttgtgc ccatacggat ccattctgtt atcgaaggag ttagtgctga
    48361 tagaagtctc aagctgttgg gtgaatccca gaatcatacc gacgtctctc aggtcgagct
    48421 ctgttccacg cgggatagga gaaccatagt attgctctaa gacgcgtcgg attgcctcag
    48481 tcggcgcatc cgcatagttc ttcgggtcca cggataagat ctttgctaca atatcaggcc
    48541 catcgacgac ttgggaaatg caatccgtaa aggtcccgcc tcggtctgct catcatattt
    48601 agaactgagt ctcatcaaat ggtcttggct tagagtatga gctctccact aaccaattga
    48661 tatgcgtaat ggctttgtgg ttggaatctt gggcattttg gtccgagctg tggcatgtaa
    48721 gttttgtgct cacgctgcgt atcagtttcg gtcttgaatg acaaacatat attgaaagtt
    48781 ttcggaaaga ttgatatttt ccaacaacac caactgcttt ttttacttgt cctccgctga
    48841 gccaaatata tataccattt atatgaagca taggaaaggc gttaatggtc cgcggtatct
    48901 gaaaagggat attgaagtgt tgttggaagt ggatttgaag ttcggagaac gctccgcggt
    48961 ggaggtggag gtggaggtgg agcgagcggg gtgggctggt ggagctccac cgaccggcca
    49021 acctgattag tgcaccagat aatttacaag acgggccgga caatcagcgg ctcggtaagc
    49081 attcctggga actaccttgg agattttctg gagccataag aaggtcatgt agcccgattg
    49141 ctactcgaga tttttggctg agccgaagcg ttgaaattca aacggcagat ccaatcttga
    49201 ctttcctttc tcatcatggg ctctatcggt gatcactatg agtcaaaggc tcgaaaagga
    49261 gctagtatgg gacggcatgt tccttacgag atcatcgatg agccaagccg ctctcgacgc
    49321 aaaatccgaa ttgttgtgat cggagcaggc gcaagtgcgt taaatttcgc gcacgatatt
    49381 gaccagagta cgttggacat cgagttagtg ctctatgaga agaaccccga ggttggtggt
    49441 acttggtttg agaatcgtta ccccggatgt ggatgtgaca ttccctctgt gaattatcaa
    49501 ttctcatggg cgccttctcc cgactggacc tcattgtacg tatagctcgg tccccgaatc
    49561 ttcatcttca tcgagctgat atgagccggt gcagttactc aagcgcgcct gagatattta
    49621 agtatttcaa aggcatcgcg gacaactatg gactacgcaa atatattcgc ctcgaccaca
    49681 gagtcgtggg cgcatcgtgg gacgaagata gcgaacagtg gcatgtgaag attcaaaggg
    49741 gtgacaatcc agcgaatgtg tttgaggatc gatgccacat cctagtcaac gcatccgggg
    49801 tcttgaagtg ggttaaacag gtaaaaattg atgtaatgac taagcaagca ctaaccttct
    49861 gagtagcaag tggaaatggc ctgctattca aggccgagaa acctttcaag ggcccatgct
    49921 tcatagtgcg cattgggatg atcaagtgga attgaaaggg aaacgcgtgg ctgtgattgg
    49981 ttcagggtcc tcagcggtac aaatcgttcc gactattcaa ccaagtgagt ttatgaacaa
    50041 ttgaactaag gtctcctttc tcacggtcaa tagcggtgtc ttccctgaaa tgctttatcc
    50101 gtagcgcctc ttgggtgact gcaggatttg gccagcgctt cgcgggaaag ggagggacga
    50161 acttcaaatg tcggactcct ttgcgcctta ttaagcaagg cagtgcgagc taacagcttt
    50221 cagatactgc gaaccagaag aacatatttc ggaacaaccc tcagaaatat ctagct
//
