LOCUS       NKJJ01000020.1         21331 bp    DNA     linear   PLN 19-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   NKJJ01000020
VERSION     NKJJ01000020.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 06:54:43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 911166
            Orig. end    :: 932497
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21331
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[922429:922497](-),
                     [921291:922366](-), [921166:921241](-)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(join(10001..10075,10126..11200,11264..11331))
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..21331
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21331
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            join(604..1470,1531..2231,2657..3869,3922..4872)
                     /locus_tag="CAN33_51605"
                     /product="aconitate hydratase mitochondrial"
     gene            604..4872
                     /locus_tag="CAN33_51605"
     CDS             join(604..1470,1531..2231,2657..3869,3922..4872)
                     /codon_start=1
                     /db_xref="InterPro:IPR000573"
                     /db_xref="InterPro:IPR001030"
                     /db_xref="InterPro:IPR003663"
                     /db_xref="InterPro:IPR005828"
                     /db_xref="InterPro:IPR005829"
                     /db_xref="InterPro:IPR006248"
                     /db_xref="InterPro:IPR015928"
                     /db_xref="InterPro:IPR015931"
                     /db_xref="InterPro:IPR015932"
                     /db_xref="InterPro:IPR018136"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036008"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF00083"
                     /db_xref="PFAM:PF00330"
                     /db_xref="PFAM:PF00694"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1169:sugar
                     transport protein (Score: 262.9; E-value: 8.7e-80)"
                     /gene_kind="transport"
                     /locus_tag="CAN33_51605"
                     /note="GO_component: GO:0016021 - integral component of
                     membrane [Evidence IEA]; GO_component: GO:0016020 -
                     membrane [Evidence IEA]; GO_function: GO:0022857 -
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0003994 - aconitate hydratase activity
                     [Evidence IEA]; GO_function: GO:0051539 - 4 iron, 4 sulfur
                     cluster binding [Evidence IEA]; GO_process: GO:0055085 -
                     transmembrane transport [Evidence IEA]; GO_process:
                     GO:0006099 - tricarboxylic acid cycle [Evidence IEA]"
                     /product="aconitate hydratase mitochondrial"
                     /protein_id="ncbi_CAN33_51605-T1"
                     /transl_table=1
                     /translation="MAGLTLPVVGTRLQIALVLLIVAPSFILFGYNQAVLGSLLSLQSW
                     VSVFPAIDTINTSGAQKSHNSTSQGACNASFQMGCLIGALSLSLYSDKLGRRKTVFIGA
                     AITVLGQALQVSATTLVQLVVGRVILGFAIGQISGTVPVWLSECASPKYRGQLGICTGI
                     FISTGYTLCNWIDLGFSYLPSSTGQWRAPLSIPFLFSAMLLVSAFTFPESPRWLISRGR
                     VEEATASLCRYRGKDAHDEMIMGEIAHIQLALEGSGTMSVLDIFDRKDKTRLLLRFWLC
                     MGLNFFQQACGGNLISVYSSTIFQNYLHMTPTMSKVLASCVLSWKTLCCLLTFWTIDNW
                     GRRLSFMVSGAGMSICMAVLAVTTGLGKITHAMAIAYVAFMFVFNFFYPIGFMGGNFLY
                     TAEIAPVRLRAAMSSLATANHWLWNLVVVLVTPVAIDTIGCWYYVIYALISATIPVCVY
                     FFYPETRHRSLEMLDRVFVDAPSIWRIVPMARGLPLGEVGTAESGDTLREEKKAEDIDG
                     NVEMREYDRPLTYAEKVLYSHLDITFDERIERGKTQLKLRPQRIACQDATAQMALIQFM
                     SAGLDTAAVPTTVHCDHLIVSRDGETQDLARALDNHKEVYDFLESACQKYNMGFWKPGA
                     GIIHQIVLENYAFPSGMMVGTDSHTPNAGGLGMIAIGVGGADAVDVMAGLSLELQAPKV
                     LGVRLTGQLSGWASPKDIINAVAGTLSVKGGTGSIIEYFGPGAQTLSATGMATVCNMGA
                     ETGATTSIFPYAPQMADYLRANHRHEMADAVKSIAPELQADEGAEYDNVIELDLSTLEP
                     RINGPFTPDFSTPVSRFGEAVAENQWPVELTAALIGSCTNSSFEDMGRAASLAQQALDA
                     GLEPQMPLLVSPGSVQTRETLEDAGILPVFERLGATMLPNACGPCCGSWDRVDMPKGTP
                     NSIITSYNRNFSGRLDSNPATNVFLASPELVIAKAFSRDLSFNPTTDSLPTPSGEQFHF
                     LPPTSDSLPSKGYLSSDSAYAPPPANRDNISVKIDPSSLRLQKLSPFPPWPGHDFKDCA
                     ILIKTAGKCTTDHITPAGPWFRYRGHLENISNNTLIGATNAENGKVNSIRNQLTKQDGQ
                     EVPATARHYKENSVPWVVIADHNYGEGSSREHAALQPRYLGGVAIIAKSFARIHEANLK
                     KQGLLALTFDNEKDYERIRAEDRVSILGLREGEFVPGSTLRLVVNGGEWEAVLRHSFTE
                     EQIGYFRSGSALNVMAGK"
     mRNA            complement(4967..6268)
                     /locus_tag="CAN33_51610"
                     /product="Aminotransferase class I and II family protein"
     gene            complement(4967..6268)
                     /locus_tag="CAN33_51610"
     CDS             complement(4967..6268)
                     /NRPS_PKS="Domain: Aminotran_1_2 (75-426). E-value: 1e-48.
                     Score: 158.0. Matches aSDomain:
                     nrpspksdomains_CAN33_51610_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="InterPro:IPR004838"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="PFAM:PF00155"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 162.4; E-value:
                     2.6e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_51610"
                     /note="EggNog:ENOG41; GO_function: GO:0030170 - pyridoxal
                     phosphate binding [Evidence IEA]; GO_function: GO:0003824 -
                     catalytic activity [Evidence IEA]; GO_process: GO:0009058 -
                     biosynthetic process [Evidence IEA]"
                     /product="Aminotransferase class I and II family protein"
                     /protein_id="ncbi_CAN33_51610-T1"
                     /transl_table=1
                     /translation="METSALSQRARTVVSSRNNLMWDILKNPWCPTTKPDGYVNVGVAE
                     NALMHDYLLEYINTKLTLPAKYLTYNDGAIGAERLRRAMASFLNKHLQPFKPLTINDLL
                     VTNGVSSAIEHISWAFTDPGEGILLGRPYYGTFIPDMSLRPGATVVPVEFNDSDPFSLE
                     AVDCYERALLTFQQDTGRKVRALMLCHPHNPLGRCYPRETIIRLMQLCQKYQIHLISDE
                     IYALSVWENTVDEHTPVPFESALSIDTTGIIDPSLLHALWGMSKDFGANGIRLGVIISQ
                     NNPTLHKALQGVSLYSYSSSVSEHVAATVLEDTDFTTRYIQLNRQKMSESYAFAVQRLR
                     ENGIEYAPGVNSAFFLWVNLGKRYRELHPEQTADLGDEISDKVMQLLLQRKVFLASGVL
                     FGSEHSGWFRIVFTHPREYLEEALRRIVVALNDL"
     aSDomain        complement(4991..6043)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_51610_Aminotran_1_2.1"
                     /evalue="1.00E-48"
                     /label="CAN33_51610_Aminotran_1_2.1"
                     /locus_tag="CAN33_51610"
                     /score="158.0"
                     /tool="antismash"
                     /translation="GAERLRRAMASFLNKHLQPFKPLTINDLLVTNGVSSAIEHISWAF
                     TDPGEGILLGRPYYGTFIPDMSLRPGATVVPVEFNDSDPFSLEAVDCYERALLTFQQDT
                     GRKVRALMLCHPHNPLGRCYPRETIIRLMQLCQKYQIHLISDEIYALSVWENTVDEHTP
                     VPFESALSIDTTGIIDPSLLHALWGMSKDFGANGIRLGVIISQNNPTLHKALQGVSLYS
                     YSSSVSEHVAATVLEDTDFTTRYIQLNRQKMSESYAFAVQRLRENGIEYAPGVNSAFFL
                     WVNLGKRYRELHPEQTADLGDEISDKVMQLLLQRKVFLASGVLFGSEHSGWFRIVFTHP
                     REYLEEALRRIV"
     mRNA            complement(join(10001..10075,10126..11200,11264..11331))
                     /locus_tag="CAN33_51615"
                     /product="farnesyl-diphosphate farnesyltransferase"
     gene            complement(10001..11331)
                     /locus_tag="CAN33_51615"
     CDS             complement(join(10001..10075,10126..11200,11264..11331))
                     /codon_start=1
                     /db_xref="InterPro:IPR002060"
                     /db_xref="InterPro:IPR006449"
                     /db_xref="InterPro:IPR008949"
                     /db_xref="InterPro:IPR019845"
                     /db_xref="InterPro:IPR033904"
                     /db_xref="PFAM:PF00494"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="CAN33_51615"
                     /note="GO_component: GO:0016021 - integral component of
                     membrane [Evidence IEA]; GO_function: GO:0016740 -
                     transferase activity [Evidence IEA]; GO_function:
                     GO:0016765 - transferase activity, transferring alkyl or
                     aryl (other than methyl) groups [Evidence IEA];
                     GO_function: GO:0004310 - farnesyl-diphosphate
                     farnesyltransferase activity [Evidence IEA]; GO_function:
                     GO:0051996 - squalene synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]; GO_process: GO:0009058 - biosynthetic
                     process [Evidence IEA]; GO_process: GO:0006696 - ergosterol
                     biosynthetic process [Evidence IEA]"
                     /product="farnesyl-diphosphate farnesyltransferase"
                     /protein_id="ncbi_CAN33_51615-T1"
                     /sec_met_domain="phytoene_synt (E-value: 5.6e-07, bitscore:
                     25.2, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MEYISSALYYVFHPYQLRDILKWKIQHNRIYRLNLRNESESRKVC
                     FKFLDQTGRSFSAVIKELHPELLVPICIFYLVLRGLDTIEDDPSISVKAKAALLRGFED
                     VLVKDGWTYDGNRPEEKDRELLVHFHHVINEYKALKPACRLIIKDITRVMGNGMADFCH
                     KVTLSNPDKAGVMTIAEYDLYCYYVAGCVGEGLTRFFIEAQLCNSSLLDYPKLSRSMGA
                     FLQKTNIIRDVSEDHGDHRCFWPKQIWSKYVSDFADLFKPENCEAALDCSSEMILNALE
                     HAKDCLVYLAKLNEQSIFNFCAVPQSMAIATLELCFRNPALFEQDVNVKISRGDACQLM
                     IECTQGLPGLCRIVSRYARRIKTKNSQSATNLSEINTVCDSIEKAVEELFHTEEGQTHQ
                     CNEDEQ"
     mRNA            join(12814..13027,13089..13738)
                     /locus_tag="CAN33_51620"
                     /product="hypothetical protein"
     gene            12814..13738
                     /locus_tag="CAN33_51620"
     CDS             join(12814..13027,13089..13738)
                     /codon_start=1
                     /locus_tag="CAN33_51620"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CAN33_51620-T1"
                     /transl_table=1
                     /translation="MIQGSRNFPGDDLLVQMIKLQRITSKVTDVRIQLRDADCEQSTRL
                     ISPYISALNSQLAETRKSFPPQVAADKVLEAMALHTEICINDLIFIRLRQTPLLADTSS
                     MEALLTCLNAAKRAVDIMFNFKPTDYIYFPFFLWRQFRTVILTLIRLASLEDPAWDVNM
                     VRRTVDITSILDRTAENLSNVQPTSDEGDDHENVVAKSLAWVKRMRSCLLAVYGQSTDA
                     QTPTSEVNGSMGIPGVKTLLSGQAAWDVSLLNGGSGMDIFSSFEEDIFGEDISGWWPQL
                     YSENGL"
     mRNA            complement(13965..14639)
                     /locus_tag="CAN33_51625"
                     /product="Glutathione S-transferase N-terminal domain
                     family protein"
     gene            complement(13965..14639)
                     /locus_tag="CAN33_51625"
     CDS             complement(13965..14639)
                     /codon_start=1
                     /db_xref="InterPro:IPR004045"
                     /db_xref="InterPro:IPR036249"
                     /db_xref="PFAM:PF13409"
                     /db_xref="PFAM:PF13417"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_N_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_51625"
                     /note="EggNog:ENOG41; GO_function: GO:0005515 - protein
                     binding [Evidence IEA]"
                     /product="Glutathione S-transferase N-terminal domain
                     family protein"
                     /protein_id="ncbi_CAN33_51625-T1"
                     /sec_met_domain="GST_N_3 (E-value: 1.1e-06, bitscore: 25.2,
                     seeds: 52, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MRPPVTRNAAAVNPWKARLALNFKNAPYSTTWVKLPEVSKVRRSL
                     NLPACRKFADGSDFYTLPILSDPTTNSLIGDSFDIAVYLQKTYPASGGGDLFPPQNLDY
                     ELKEELKVLVPLSERNDIEYADYARFNNNVDAAFSVHTMLMVQKMPFDPETAEESKAEF
                     VRRAGLKSWDDFTLEGEKREQVLASFREMLKDLARMFERDPSGPFLLGRGRVMRILLSE
                     GG"
     mRNA            complement(join(15434..15548,15609..16516))
                     /locus_tag="CAN33_51630"
                     /product="short chain dehydrogenase family protein"
     gene            complement(15434..16516)
                     /locus_tag="CAN33_51630"
     CDS             complement(join(15434..15548,15609..16516))
                     /codon_start=1
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF00106"
                     /db_xref="PFAM:PF08659"
                     /db_xref="PFAM:PF13561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     102.9; E-value: 3.2e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_51630"
                     /note="EggNog:ENOG41"
                     /product="short chain dehydrogenase family protein"
                     /protein_id="ncbi_CAN33_51630-T1"
                     /transl_table=1
                     /translation="MASKDLSPSTAPFFPNVFFYNQFCAKPNWPPATTNLSGQVAIITG
                     GNTGLGFECASQLLSLQLSHLILAVRSLEKGEAAAAKLRAVNPTSTIDVWPLDMSSYDS
                     IQSFAKRVENNLSRLDIAILNAGVRQAQFTTNPSTGHEETIQVNYLSTMLLAILLLPSL
                     RDKSPKGVPGRLTIVSAALSLLPSLPNVKDAPLLKLFDRPDTYDANGIYCMSKLLAHAF
                     LYKLVEYVGADDVIVNLADPAFVKGTDLSRDSPGLAKAGLAVFGVLTGRTVKVGASTFI
                     DAAVLKGKESHGCFLMSWKIEPFNASLYTPEGKQSIEQLWQETMDELDFAGVRRILETL
                     "
     mRNA            complement(join(17001..17539,17588..17680,17728..18193,
                     18258..18353))
                     /locus_tag="CAN33_51635"
                     /product="hypothetical protein"
     gene            complement(17001..18353)
                     /locus_tag="CAN33_51635"
     CDS             complement(join(17001..17539,17588..17680,17728..18193,
                     18258..18353))
                     /codon_start=1
                     /locus_tag="CAN33_51635"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CAN33_51635-T1"
                     /transl_table=1
                     /translation="MDSAALNITSSQASQTPPAIGDIGRITQRQYGIAVGVFFALASLS
                     FFGRIFIRLFTRRRLYLDDAFLSFAFTTLLIGTVLGFLRAYTIYFQMAALEGNVGAVLF
                     LASHLNEHAKDYGFNIAFIVLLWTTVFAVKWCYLAFFQPLLVGMSRWFIIYYRFTVGLS
                     VISWILSAFVAPIVPCPYTGMKAISKCFPTLPVPNSTVLAMIWLPPILDAVTDLMIISI
                     PIRLLYKVQLRTLTKLGLGCFLCLSIFMCTCSIIRTAGTWYHGLLDYPWQVFWLHLEGC
                     IGVTMGSITVYRSTLIGSNEVSTAFKKYFTRIKDAVLGSSSGTAQASPTEENKTRTRQF
                     GLPSIPQATITGLRTWFGLSRRDPAASNDASGISSFNSDIDYHTLLKAPKAAAGHRQ"
ORIGIN
        1 aagatattcc aatttctcaa gcgggagtaa attccctgta atgatcgtga ttgtactttg
       61 ccattaacgt aataaccatt agtcatgact atatataatc tgtcggaaca tacaccgtag
      121 ccacaaaccc accaagacct ttactcggtc aagatataac gcacctgcct gcttttcgaa
      181 acttcactaa gcattatcat gagacgacta tgcactaggc tggtatctgc atagtactcc
      241 atatgaacca cactgcctta taggttcatt cgccacctgt gagtcgtttg ataaagtcta
      301 tcggagcatc cgatggaaat tgagtgcagc gacactcata cccacctggg atgccaaacc
      361 cacaactgat gatcagacgg tcgagacgag ggacaagaaa gacaacgcca gacagtcata
      421 gacatcttcc aatcagacaa tagcagatat aatgactaga accgatcata ccatggagac
      481 gtgtgcaccc cgctttttct tccttgacgc cacatcctct tccccacggg ggatcagacg
      541 gaaagtactt aagccgccta gtaagtctct gaaccaaagg tcaagcaggg aatgaaagtg
      601 aaaatggcag gccttactct ccctgttgtc ggtacccggc tccagatcgc tctggtactt
      661 cttatcgttg ccccttcgtt cattctcttc ggatacaatc aagcggtcct gggcagttta
      721 ctcagcctcc aaagttgggt ctctgtattt ccagccatcg acaccataaa cacctcgggg
      781 gcacagaagt cccataactc aacatcccaa ggcgcctgca atgcctcgtt tcagatggga
      841 tgtctgatag gtgccctgtc cctctctctt tatagcgaca aactcggacg ccgtaagaca
      901 gtctttatcg gagctgccat caccgtcctc ggtcaggctc tacaggtctc tgcaaccaca
      961 ttggttcagt tggtcgttgg ccgagttatc ctagggttcg ctatcggcca aatcagcggc
     1021 accgtgcctg tctggctctc ggagtgtgcc tctcccaagt accgcggaca gctcggtatc
     1081 tgtacgggta ttttcatcag cacgggctac acattgtgca actggattga tttgggattc
     1141 agctatctac cctcttctac tggacaatgg agagctccgc tctctatacc ctttctcttc
     1201 tcagcaatgt tactggtttc tgctttcacg tttccggagt cgcctcgttg gctgatctct
     1261 agaggaaggg tcgaagaagc tactgcaagt ctctgtcggt atcgaggaaa ggatgcgcat
     1321 gatgagatga ttatgggcga gatagcccat attcagcttg ctctagaggg cagtgggacc
     1381 atgtccgtcc tggatatttt cgatcgcaag gacaagacgc gtctgttgtt gcgattttgg
     1441 ctctgcatgg ggttaaactt tttccaacag gtgagtatcg cggctcctat agcacttggc
     1501 tctccaaatg taccaccgct aatccattag gcctgcggag gcaacctcat atccgtctat
     1561 agttccacca ttttccaaaa ttacctacac atgacaccca ccatgtctaa agtcctggcg
     1621 tcctgtgtac tatcatggaa aacgctctgc tgtctattaa cgttttggac tatcgacaac
     1681 tggggccgcc gtctatcctt catggtaagc ggagcaggga tgtccatctg catggccgtg
     1741 ctagcggtca ccaccggctt gggcaaaatc acgcatgcga tggcaatagc atacgttgcc
     1801 ttcatgttcg tcttcaactt cttctaccca atcggcttca tgggtggcaa cttcctgtac
     1861 acggctgaga ttgcgcctgt gcgtctgcga gcggccatgt cctccctcgc gactgctaat
     1921 cactggctat ggaatttggt ggttgttctg gttacgccag ttgctataga tacgattgga
     1981 tgctggtact atgtgatcta tgcgcttata tctgcgacta tcccggtctg cgtgtacttc
     2041 ttctatccgg agacgaggca ccgtagtttg gagatgcttg atcgggtgtt tgtggatgcc
     2101 ccttctatct ggcggattgt gccgatggcc agggggttgc cgctcggaga agtcggcaca
     2161 gcagagagtg gagatacact gcgcgaggaa aagaaggcag aggatataga tggtaatgtt
     2221 gagatgcggg agtatgtcta gatggattag ctggacagcg ttgctattgt aattagttgt
     2281 tcctcgggta gaagagatgc gatatgccca tcggcccagc cgacggaacc atccgaagct
     2341 gacactagga agaccgagga gtaaatcagc cacagctgga gatgttacat agacccttgt
     2401 gatttatatc tactgtctta tccaatagat cactcttgtt taccaatgca tcatcaagat
     2461 gatcagaaca cgagtgagct gtcccaagtt agccagaggc tatgcctccc acacccaagt
     2521 gccaataagt cgacttgaac aacataaaat aaacatctcc cagtttcctt ctgccatcca
     2581 atcactaaga aagcggtagc tactcacttc gcacctacgc tgcattatta gacccctact
     2641 gatatccaca tcatagatac gaccgccccc tcacatacgc cgaaaaagtc ctttacagcc
     2701 atcttgacat cacttttgac gagcgcatcg agcgcggcaa aacccaactc aaactacgcc
     2761 cgcaacgcat agcatgccaa gatgcgacag cccaaatggc acttatccag ttcatgtccg
     2821 cgggactaga cacagcggcc gtaccaacca cagtccactg cgatcatttg atcgtcagtc
     2881 gtgacggcga aacacaggac ctcgctcgag cgctggacaa ccataaagaa gtgtacgatt
     2941 tcctcgagtc tgcctgccag aaatacaaca tggggttctg gaagcccggc gcgggaatca
     3001 ttcaccagat tgtgctggag aactacgcct tccctagtgg aatgatggtc gggacggact
     3061 ctcatactcc caacgcagga ggccttggca tgatagccat cggagttggt ggtgccgatg
     3121 cggtagacgt gatggctgga ttgtcgctgg agctccaagc gccaaaggta ttgggtgtcc
     3181 gattgacggg gcagttgtcc ggatgggctt cgccgaagga tattatcaat gctgtagccg
     3241 ggacgctttc cgttaaggga ggtactgggt ccattattga atactttgga cctggggcgc
     3301 agactctgtc agccacgggc atggcaactg tgtgcaatat gggtgcggaa acaggtgcca
     3361 caacatccat cttcccttat gcgccacaga tggcggatta tcttcgtgct aatcatcgcc
     3421 atgagatggc tgatgctgtt aagagcattg caccggaatt gcaggctgat gagggggctg
     3481 agtatgataa tgttattgag ctcgatttgt ccactctcga gccacggatc aatggacctt
     3541 tcacgccgga cttttctacc ccggtgtcgc ggttcggtga agccgtggcg gagaaccagt
     3601 ggccggttga attgacggca gctttgattg gatcttgtac taactcttcg tttgaagata
     3661 tgggacgtgc agctagtctt gcccagcagg cattggatgc aggactggaa ccacaaatgc
     3721 cccttctggt gtcgccaggt agtgttcaga cgcgcgagac gttggaagat gccggtattc
     3781 tgccggtctt cgagagactc ggggcgacga tgcttcccaa cgcctgtggt ccatgctgtg
     3841 ggtcgtggga tcgagttgat atgccaaagg tatagtatgg ccatcccatc taccgaaaga
     3901 ctgtcttttg acatatatta gggcacccca aactccataa taacctccta caaccggaac
     3961 ttctccggcc gtctagattc caacccagca accaacgtct tcctagcatc gcccgagctc
     4021 gtcattgcaa aggccttctc ccgcgacctc tccttcaacc caacaactga ctcgctccca
     4081 accccatccg gcgagcaatt ccacttcctc cctccaacca gcgattccct cccctcaaag
     4141 ggctacctct cctccgactc cgcctacgca cccccaccgg caaaccggga taacatctcc
     4201 gtcaaaatcg acccgtcatc cctccgcctc cagaaattgt ccccattccc accctggccc
     4261 ggccacgact tcaaagactg cgccatccta atcaaaacag ccgggaaatg cacaacggac
     4321 cacatcaccc ccgctggccc gtggttccgc tatagaggcc acctagaaaa catctccaac
     4381 aataccctca tcggcgcaac caacgccgag aacggcaagg tgaacagtat ccggaaccag
     4441 ctcacgaagc aagatggaca ggaagtgcct gctacagcac gccactacaa agagaacagc
     4501 gtgccgtggg tggttatcgc tgaccataac tacggggagg gcagttcgcg ggaacatgcg
     4561 gcgctgcagc cgaggtatct aggtggtgtg gcgattatcg cgaagtcatt tgcaagaatc
     4621 catgaggcga atttgaagaa gcaggggttg ttggcactga ctttcgacaa tgagaaggat
     4681 tatgaaagga ttagggctga ggatcgggtt agtattttgg ggcttaggga gggggagttt
     4741 gttccgggga gcactttgag gttggtagtt aatgggggcg agtgggaggc tgtgctcagg
     4801 catagtttta cggaggagca gattgggtat tttagaagtg ggagtgcgtt gaatgttatg
     4861 gcggggaagt agttgaagtg tctagatgat gggctgtgtg gtggtttgtt gatagatttg
     4921 tctatagcca atgtgtattt gtatgctatg tgatactcta accatatcat aaatcattca
     4981 acgccaccac tatcctccgc aacgcctcct ccagatactc tctcggatgc gtgaacacaa
     5041 tccggaacca cccactatgc tcagacccaa acaacacccc actagccaga aacaccttcc
     5101 tctgcaagag aagctgcatc accttgtcgc tgatctcatc acccaaatcc gcagtctgct
     5161 cgggatgtag ttcgcgatac cgcttgccca agttaaccca aaggaagaac gcagaattga
     5221 cacccggagc atattcaatc ccattctccc ttagccgttg aacagcgaac gcatacgact
     5281 cggacatctt ctgccggtta agctggatat acctcgtagt gaaatctgta tcttcaagaa
     5341 ccgtagcagc gacatgctcc gagacagagg aggaataact atataacgag acgccctgca
     5401 acgccttatg aagcgtgggg ttgttctgag agataatcac tccgagacgg ataccattgg
     5461 cgccaaagtc cttgctcatt ccccacagcg catggagtaa actagggtca atgatgccgg
     5521 tcgtgtcgat cgataaggca gattcgaatg gcacgggagt gtgctcgtca acggtattct
     5581 cccacacaga caaagcgtat atctcgtcgc ttatcagatg gatctgatat ttctgacaca
     5641 gctgcatcag acggatgata gtttcccggg ggtagcaccg gcccaacggg ttatgtgggt
     5701 gacagagcat gagggcgcgg actttccggc cagtgtcttg ctgaaacgtg agcagtgcgc
     5761 gctcgtagca gtccacggcc tcgagactga atggatcgct gtcgttgaat tctacaggga
     5821 caactgtcgc cccggggcgg agggacatat ctgggatgaa ggtgccgtag tagggtctgc
     5881 ccaagaggat gccttcgcca gggtcggtga aggcccatga gatgtgctcg atggcggagg
     5941 agacgccatt tgtgacgagt aggtcgttga tggtcagtgg tttgaatggt tgaaggtgtt
     6001 tgttcagaaa agatgccatg gcgcgtcgga ggcgctctgc accaattgcg ccgtcattgt
     6061 aggtgaggta tttggctggg agggtgagtt tggtgttgat gtattcgagg aggtagtcat
     6121 gcatcagtgc gttttcggca acccccacgt tcacgtagcc gtcgggttta gttgtgggac
     6181 accatgggtt ctttaggatg tcccacatga ggttgttgcg ggaggagacg actgtgcggg
     6241 ctctctggga gagggcggag gtctccatct tgttggatgc agggctgtat actacgatta
     6301 gggtgtgttt gtggtaaaat atgggcttgg ggagccagaa gagaagtgag gatttgacac
     6361 acgtgaggag gttgactcca ctggatgata cggatatccg cgggttcttg gcagttccag
     6421 aaaacactga ggtgttctgg ataagtagtt gagatgttag ggtattcaag ggacggtgat
     6481 ggtaccgata ctgttgatac ggaagtgagc tggacgcagt gtagacacct tactttccat
     6541 agatgtagac tgcttctgtg cgcccaggag ctcagtgaat tacatcacag tgaagcatgt
     6601 gaaccaaatt ctgctttgtg tttggtggtt cgcttagtgt tgactcaagg ttggtcggga
     6661 acctaatatc cccaccatgg atgcgctggt ggagaaagtt tacgggagat gaagaacttg
     6721 tgtggtatac cggagggtgt ggttcggcag gccgagctcg gtgaagtggg tcatcacggg
     6781 tttctgtttg tcaatcttgt ggatgcttca tgatgtgggt gataaccacc tcctttactc
     6841 cgcattgagg acaggaatgc cagcctaaag aggggcgatc accggcaatc ccttgcggga
     6901 gacagttaag gtagaaggcc aaatagtatg cctgataagc tctgtgacac atcgcgtcta
     6961 agatggcctg tatggtgaat gcgtctcaaa gcatgtggcg atactttctt ttggtctcaa
     7021 gcaggatgga gtcacgaata taagcaggct ctgagaagag attgtgtacc aaaaatttcc
     7081 atcttttggg ggacacgcct ggcgtaactg tggtcgtctt ggttatgtag cacaaggtac
     7141 ataactgggc tctaatttct ggtgactgca cgtccactgt ataaaatatt gtagtgatca
     7201 gagtagaaag acgcaatgaa ggtgacagaa cccgaaagat taactatctg aacgttgggg
     7261 agacggataa caatgggctc agtcctgtct ctttccccgg aattcagggc tagtgggaaa
     7321 gcatttcagt atttgactgg gataacgggc gtaacatgag gccaaacttc tataggggat
     7381 gtggatcttg ggggcataca ccgacgacgt aaattcattg actgggcaga agggagctat
     7441 tcttgaggca attcgagaat agctcaatgc cggtgtcata accgtcacat ctgcctgatg
     7501 ctcctcattt atctggaata gccagcacgg ggttcgaaag aagcgatagc ccatctcctt
     7561 atcatccgga gcccaataag ttccacatga aggttcttaa tccccagcaa ccatcagtta
     7621 acgtgtgtcc catctagcat gcactagtcg tcgtcatgga ggtacctggg ggttggtggt
     7681 catcagccac gttcgaatct tgccagaaga gactcaatag gcccggataa caagtcattt
     7741 gtccagaata tagtcagcta ccaacagata gaatatatgg ccaacgaata ctatcactga
     7801 accacgtagt tgaagtgtgt gtgttttact taaccatcca ggaactctcg ctagcttggg
     7861 catagagtgt caacatacag agataccact tgcatctggt tttgccggct tacaatattt
     7921 tttcaagcga gaaggatgat aacaagctag ggtctcaatt tgaattgcta tagcagatta
     7981 ctaactagtc cgagaagaca acgggcatta ctttgtagta ctgattgcac cccactgcag
     8041 ctatcactat gaatgtagta aaccataggg gccgcgtgag ctagttattg gataacttca
     8101 ggacttccat ttacggttcc cgtatttgaa ttccatggtg gtggcattac atcctcattg
     8161 aaatccaccc atccagggtc atcgttggga tctttgtgtt caacccaaaa ttgattcttc
     8221 acgtctcccc attcgtattc gtcgccacgg ggaactcggg ggtaagcccg cattggttgg
     8281 taacaggctt tgtaggcagc acacgttaga aaatgctccg gtagatcggc ctctcgatac
     8341 gaccgatgat aggcccacct acttggtggg taatccgcgt gttcatcaga gctcatggcc
     8401 cttgaccagt cgtgatagca agcccagcaa taagtccctc gctccaaggt ttttgtgtcc
     8461 ttatcccaaa aagggaatgg agcggtagcc atgaattgta actgttcgca gccgttttca
     8521 taccaaacac tcgcgctccg ctgatgtcca aaaccccgat atagaggccc tgacagatcc
     8581 cattctccga aagccgctcc taaactttca atggtacgat gtacttcacg tgttatcttc
     8641 aatgatcctt tgggcccgtg aagtatgata gctatagcgt tcccatgagg gacgcttacg
     8701 agacgggccc cggatttcca cgtactgtgg acaattggaa tatcccggag atctgtttct
     8761 ttcagaccga aataaaaaca aagatccttc acgctggcca ttctgtacat tagattgtga
     8821 taattacaat tgtaacagca acgggtgagc gttgcaaggt gcaggtatgg tccgaagtca
     8881 ttacaggttc gacaccgagg gtgggtgaac tcggtatata gctgttcaat ggtgaaatag
     8941 tgggagagac gcatccggtg cattagatgc aatgtttcag aggctttgtc tctaagcaag
     9001 agatacgggc ggactgattc aacttggaat tttgataccg tatccactag aagcatcttc
     9061 cctatgctgg ccaagttgag gtagagaagt atatgctgaa ttatctcaaa cggcaggaaa
     9121 agaccgagga atcgactagg atcagcatta gattccctgt tgcccttcga caagagtgtc
     9181 atctctctcc ggtccgggag atgtggctgt tcatagttgg gaaaatggaa gacctcgctg
     9241 atcgggttgt cgatccgata ggcaaagccg gatgccatcg tgtaagacga gagggtttta
     9301 gaagttattg actagattga gaaagtgagt tagattattt ccaaatggct aatctggtgt
     9361 gatggagaac aggttcatac aggtgtttgt cgaagtcgac acgtaggatg cacagttgta
     9421 tgtgatagta ggagagttga ggaattctct gtatcacaat gtgaatgaga tattataccc
     9481 cgcatcgtcg cggcaacact atgatagcac cagtacgtgc aactgcaaac agcaacttgg
     9541 gccgaaatcc aatctgtgaa tgacgacgca gcacaatgtc gtaaatactt taactcccaa
     9601 tgagctactg ctaactgcag atgctatcat atactacgaa ggttgtttat aaagatcttc
     9661 gacattccct gccaacgtct acagtttgtc caacatatcg ctatttgaag atcgctgcta
     9721 gctgcattga gacagccgct gttgacccgt gttccttgtt tgatttgata ggggaggctc
     9781 ggattgttgt tagaatggac aatccggata atgaccaagt tccgtaggct tctgtccagc
     9841 aagatgctcg cgaaggcgca ggaagagctc aatcaggtat actattttga cgcccttata
     9901 ttattattca gatgtaggat attcttccag cgattccata atgtggatcc ctcgagtaca
     9961 ctctttaccg ttgcccatcc tgctatctag cagtagtgca ttactgttca tcctcattgc
    10021 actgatgagt ttgtccttct tccgtatgaa ataattcttc gactgctttc tcgatctatg
    10081 gttgttagga ctcgcccact atgaagtaca aatgagataa cataccgaat cgcacaccgt
    10141 attgatttcg gaaagattgg tggcactttg tgaattcttg gttttgatgc gtcgtgcata
    10201 tcgactgaca atacgacaca gccccggcag gccctgtgtg cactcaatca tcagctgaca
    10261 tgcatcaccc ctgctgattt taacattgac gtcctgctca aacagagcgg gattgcggaa
    10321 gcacagctct agcgtcgcga tagccatgct ctggggtaca gcgcagaaat taaagatgct
    10381 ctgctcattc aacttagcca gatagacaag acagtccttg gcatgttcta gtgcgttaag
    10441 aatcatctca gaactgcagt ctaaggccgc ctcacaattt tctggcttaa atagatctgc
    10501 gaagtcgctg acgtacttag accatatctg tttgggccaa aagcaacggt ggtctccgtg
    10561 atcttcactg acgtcgcgga tgatgttggt cttctggagg aaggcaccca ttgaccggga
    10621 taacttcggg tagtcgagca acgacgagtt gcaaagttgc gcttcgatga agaagcgggt
    10681 aaggccctcg ccgacacagc cggcaacata atagcagtac agatcatact cggctatagt
    10741 catgacaccg gctttatcag gattgctcag ggtaaccttg tgacagaagt cggccattcc
    10801 attacccatt accctggtga tgtccttgat aataagtctg caggctggct tcaaagcttt
    10861 gtactcgttg ataacgtggt ggaagtgaac aagcagttcg cggtccttct cttcgggacg
    10921 gttgccatcg tatgtccacc cgtccttcac caatacatcc tcgaagccgc gaagcaaggc
    10981 agccttagcc ttcacagaaa tagaagggtc gtcttctatg gtgtcgagac cacggaggac
    11041 caggtagaag atacaaatag ggacgagcag ttcggggtgg agctccttga taacggcact
    11101 gaagctccgg ccggtctgat cgaggaactt gaaacagacc ttccgggatt cactctcatt
    11161 cctgagattc aatcgataga ttcgattgtg ttggatcttc ctatgaccgt agcatgcctc
    11221 ccgtcagcta tcaatagtag gttaatgggt gagtgataac caccatttca gaatatctct
    11281 caattgatat ggatgaaaga cgtagtagag agcgctgctg atatactcca ttctcatatg
    11341 tggataaata agagaaacac ctcttgtaac gatgatactc atggtttggg ctccgggcct
    11401 tttaagggta tagaaagtgg aagcggagcg gagcgggatt cgcaacccgc tattttagtt
    11461 gccgaagcgg atttcgaatt ttcaacctcc cgaaatccgt ccgctggggg gttcagccaa
    11521 ttccagagac accatattcg cgttgcagcc acgccagacc tcaaattgga ctatacagct
    11581 tcacaattat atccatcttc acagtgcccc attaaatgga agatataaca catagtcgtg
    11641 gaaaggcggc cccatatggc cgagcgtgcg tcagctgtgc ccgcgtaaaa cgcaagtgca
    11701 tactgcgagc caatggagat ggatgtgaaa gctaattttc ggaaagacta ttggtgatga
    11761 ttggctcata ttcatggtca gatgctttcg tctaaaagta gaatgcagac cttctcctac
    11821 cgtccgcagg cgtggctcca agcccaacgg ctctcaagcc gctcgtctag agcagaaatt
    11881 agatgggctc gtttcattat taaaagctcg ccagggttgc cctgagatcg gagatacagc
    11941 atcatcatcc gcgtccttca catcagctct gtctcacgct tcagtgcctg cagatcgtgg
    12001 gtcccacgca caaccgcttg ttggtgatct tgatagagta gctacagatc atggcaagtc
    12061 tcgccattgt ccattaccaa gatcagccct tttaacagaa agctcgagct ttcccccgta
    12121 tagccttccg gctggcgtgg agccaactcc tcgcaataca aaacaacgtt tgaggacatt
    12181 ttgcaaccac tacgctaaat tcctccctct tatatatctc gagaacggtt tgacttcgga
    12241 aaagttgtat cgagagtcac cattcctctg gctatgtata atggctgtga catctacaaa
    12301 tgccaaagaa cagagcactc tgggaaaggc ggttcgagag gttgccgctc gtgaggtaat
    12361 tgtagaaggc aaatgtacaa cggatctgtt acatggtctc ctctgtttca tcggttggtc
    12421 cgtttttctt atcacacttt gctatccgcg tgactgatag tgatatatag gggacacttt
    12481 cggttctcta tgggatcact tcttactatt ttgtctcatc tgtgcactgc tttgacggta
    12541 gatctggaac ttcgaagtcg gcattatgga gagggcaatt tgtgtcatat atttccgcga
    12601 cccatagcag cccaaatcca gggagctact gggacatatc aaccgaggag ctttgaaaat
    12661 gcacggacag cattagcttg ctactttctc acgtcatggt tagcccttct ttggaatatt
    12721 tagaatgccg ctaatagcac gatcagtatt gcaacattcc agacagtagg ggagaacttg
    12781 gcctggtcac catacatgga agaatgcttg aaaatgatac agggttcgag gaattttcct
    12841 ggagacgatc ttctcgtgca gatgatcaag cttcaacgca taacgagcaa ggtcactgat
    12901 gtccggatac aattaagaga tgccgactgc gaacaaagta cgcgtcttat ctctccatac
    12961 atatctgccc tcaactccca gttagcggag accaggaaat cgtttccacc acaagtggcc
    13021 gcggatagta cgttcaaccc acaaatagct gacagaaatc cacgctaact ctgattcgaa
    13081 ttcaatagag gttcttgaag caatggctct gcacacagaa atatgcatta atgaccttat
    13141 ctttatacgc ctccgacaga cacctctcct tgctgatacc agcagcatgg aggctcttct
    13201 cacttgtctc aatgcagcga aacgcgcagt ggacattatg tttaacttta aaccaaccga
    13261 ctacatatac tttcccttct ttctctggag gcaattccga acagttattc tcacactcat
    13321 tcgactcgca tccctcgaag atccggcgtg ggatgtgaac atggttcgac gaaccgtaga
    13381 tattacgtct attctcgaca ggaccgccga gaacctgagc aacgtacaac ccaccagcga
    13441 cgagggtgat gatcacgaaa acgtggttgc gaaatcatta gcctgggtga aaaggatgag
    13501 gtcttgctta ctagccgtct atggccagtc aacagacgcc cagaccccta cctctgaagt
    13561 gaacggctca atggggattc caggtgtgaa aacgttgctg tcagggcagg cggcctggga
    13621 cgtgtctctg ttaaacggag gctcggggat ggatatcttc tcatcttttg aagaagatat
    13681 cttcggggaa gatatttctg ggtggtggcc acagctatat tctgaaaacg gattataaag
    13741 attccttgct gttccatgag actttgtatg actacacgag tgaataagaa atatattcaa
    13801 ttgttgtaca ggacttttcc ttctatccat cttgtattta taactttcaa tctatttaac
    13861 ctcagcataa acatccaacg catcatgcaa ccttccaaaa acacccccat gccactctct
    13921 caactgctcc cactccgtcg acggcagcgt aaccctcgac atcctcaacc accctccgac
    13981 aataaaatcc gcatgactcg gcctctcccc aacaaaaacg gcccactggg atctctctca
    14041 aacatcctcg ccagatcctt caacatctcc cggaacgaag ccaacacctg ctccctcttc
    14101 tccccctcaa gtgtaaaatc atcccacgac ttaagccctg cccgccggac aaactccgcc
    14161 ttactctcct ccgccgtctc cggatcaaac ggcatcttct gcaccatcaa catagtatgc
    14221 acactaaacg ccgcatcgac attattatta aaccgggcat agtccgcata ttcgatatca
    14281 ttccgctccg atagcggcac cagcaccttc agctcctctt tcaattcata atccaggttc
    14341 tgcggaggga agagatcccc gccaccggag gcgggatagg tcttttgtag gtagacagcg
    14401 atatcgaaag agtcgccgat gagggagttc gtggtgggat cggagaggat agggagggtg
    14461 tagaagtcgc tgccgtcggc gaatttgcga catgcgggga ggttcaggct gcggcgcact
    14521 ttggatactt cagggagctt gacccacgtt gtggagtagg gggcgttttt gaaattcagt
    14581 gcgagtcgcg ctttccaggg atttacggct gcggcgttgc gggttactgg aggtcgcatg
    14641 gcgatgtcgt agtaggtcat tgttggagtg gggtttgagg tggtggttgt ggttgccatt
    14701 gtggatggtg gggggttcat ataatgatta gagagttgaa ttggtattaa ttgtgagtgg
    14761 aatgaaggta ataatcgaca agtgtgtgca attgagctct ttggatggcg agtttaagtg
    14821 atattcatgg cgattgaggt tgagttatat agctgggcct gggaggtaac gtcacgtgta
    14881 acattaatct cgggtggggc aggcttccca aacctggggt tctttaggcg agagatgtct
    14941 gctaaagtgt acggttctag tctttccatg gctaattctg gaaactgcaa gctgtttggg
    15001 ctggagagtg ggctgtgcaa tgatcatgat ttgatgttct catgtcgact cagaatgact
    15061 catgcccact catgctgccc aagtgggccc atgtggggtc ctatccccac tacccgattg
    15121 atctggagat cataagaggc atgcggtctt cttcaacgtc atagagttat gaaacctcct
    15181 tttattgtac tatattaggt atgcttatgc agaacatatt caaagtttga atggatcctc
    15241 ataaagcaca ggctgcagat ggggatttct tctgcacttt gccgatccaa tttttcatca
    15301 atccctaggg ccaatttcag tctgttgctg ccaacattat aattatgcag acatagcaag
    15361 tccgaatcga gcttggtaaa caagcattaa aagaggtgac tgagcgtttg cttgtttgct
    15421 cccttctaaa aaattacaga gtctcaagta tccttcgaac accagcaaaa tcaagttcat
    15481 ccatcgtctc ctgccacagc tgttcaatag attgtttccc ctctggagta tacaatgacg
    15541 cattaaacct gaacatacgt gtgtcagcca tgacgtgaaa aattcaaagg aaaggtggga
    15601 atacttacgg ttcaatcttc caactcataa ggaagcaccc atgcgactcc ttccccttca
    15661 acacggcagc atcaataaac gtcgatgcac caaccttgac tgtcctcccc gtcaaaaccc
    15721 caaacactgc tagcccagcc ttcgcaaggc caggcgaatc ccggctcagg tcagtgccct
    15781 tgacgaaggc cggatctgcc aggttcacaa tcacatcatc tgcaccgaca tattcaacca
    15841 acttgtagag aaacgcatga gcgagaagct tcgacatgca gtaaatgcca ttggcatcat
    15901 atgtatctgg acgatcgaac aacttcagaa gtggcgcatc cttcacgttt ggtaagcttg
    15961 gcaggagcga tagtgccgcg ctgacgatag ttaatcgccc tggcactcct ttcggagatt
    16021 tgtccctcaa gcttggaagg agtaggatag cgagaagcat ggtggagaga tagttgactt
    16081 gaattgtttc ctcgtggccg gtgcttggat tggtggtgaa ctgggcttgt ctcaccccag
    16141 cattgaggat agcgatatct aggcgggaaa ggttgttttc gacccgcttt gcaaagcttt
    16201 gtatggagtc atatgagctc atgtcaagtg gccagacatc tattgttgac gtgggattaa
    16261 cggcccgaag cttggccgct gcggcttcgc ctttttcgag agagcgaacg gcgaggatca
    16321 agtggctaag ctgaagagat agaagctgag atgcacactc aaatcccagg ccagtattcc
    16381 ctccggtgat tatggccact tgaccagaga gatttgtggt tgcgggtggc caattgggtt
    16441 tggcacagaa ttggttataa aagaagacgt tggggaagaa gggagcggtc gatggagaga
    16501 ggtcctttga cgccattgta agatattaat gtcagagaaa gacttcagat actttgaacc
    16561 gaaaggtgtt atttgtagag cagaagcagg ctgtctagtt ctcttgatac aagttcctga
    16621 tgatcctata tattacggtt gtcagccact aagcccaaag cggcacccaa tgtccgcgga
    16681 cttaagccgg gtgtttgccg cggtcgatcc atccttcact tcgtcttatt gttgtgctgg
    16741 agatatccta tccccgcgta tatcatatat ggcaaggcac atcttaactc cgatcccagt
    16801 aatactgtgt tgagacttgc gctgtagcca gggatcgctt gatccttcgc cacctctgtc
    16861 tacgtggtct ctgaccacca ccgcctccta cctaccaccc aaccatcatc ttgagatcta
    16921 gatagatcaa atacacacac attcgaatat cgtcctgccc tctgtctaga gaaaagattt
    16981 gcagcaatca agcctaggac tcattgacgg tgacccgccg ctgccttggg agctttcaac
    17041 aaagtatggt aatcgatatc gctgttaaag ctactgatcc cggaagcatc attggaagcg
    17101 gcaggatccc tcctggagag accgaaccac gtgcgcaacc ccgtaattgt tgcttgtgga
    17161 atggacggca gtccaaattg acgtgtccga gtcttgtttt cctctgttgg tgacgcttgt
    17221 gctgtgccac ttgacgaccc caaaaccgcg tccttgatcc gggtaaagta tttcttgaat
    17281 gcggttgaaa cctcgtttga tccgatcaaa gtggaccggt agacggtgat agatcccatg
    17341 gtgactccga tacatccctc caaatgcagc cagaatacct gccatgggta gtcgagaagc
    17401 ccgtgatacc atgtgcctgc agtgcgaatg atggagcatg tgcacatgaa gatcgagaga
    17461 cacaggaagc atccaagtcc cagttttgtc aaggttcgca attggacctt atagagcaac
    17521 cggattggaa tactaattac tgggcaaggt cagtcatagc tagtctttgt ttggttaggt
    17581 gacatactca tcagatcggt gaccgcatcc agaattggtg gaagccaaat cattgcaaga
    17641 accgtgctgt tcgggactgg taaagtggga aagcatttgg ctatacatag ttagtggagg
    17701 agcctatcgc tgaccagagg tgcttacaaa ttgccttcat tcctgtgtac gggcaaggaa
    17761 cgatcggagc gacgaaggcg ctcaagatcc acgagataac agacagcccg acagtgaaac
    17821 ggtagtagat aataaaccag cgtgacattc ccaccaggag gggctggaag aatgccaggt
    17881 agcaccattt gacagcaaaa actgtggtcc agagaagaac tataaaggcg atgttgaagc
    17941 catagtcttt cgcatgttca tttaaatgcg aggcgagaaa gaggactgcg ccaacatttc
    18001 cttccaatgc tgccatctga aagtagatgg tgtatgcgcg gagaaagccc agtactgttc
    18061 ctatcaacag tgtggtaaaa gcaaagctaa ggaaagcatc gtccaaatag aggcgtcgtc
    18121 gagtgaagag tcggatgaag atgcgaccaa agaacgacag tgatgctaac gcaaagaaaa
    18181 cgccaactgc tatctggtaa tcatagatct ttcgttagag ttatactttc ggataattat
    18241 gcttggacta gccttacgcc atattgccgc tgggtaatcc gaccgatatc acctatggcc
    18301 ggcggggtct gagaagcttg actggaagtg atattcagcg ctgcgctgtc catcttgcag
    18361 gtttccggga tgagtgaggc atagccttta gaggtgcagg tgcaattctt gacgcacctc
    18421 acagacggga ccaccgcttt atgtagagac gggctgtcag actctgtggt tgcacgaatt
    18481 gtctgggttg gatgtgcggg gacttgggcg gcgcactgga tctcctccta cataatttat
    18541 gctgactgca tttgatcgac ctcaggaagt tgacaatgcc tcccagaaga agcaaggggc
    18601 tcaagttgcc ttgagattct tagtctccct tgggaaactc ggcctcgatt cccagccagc
    18661 gctgaggact ttgaatgagc gatattgaag tttaaatttt gttccagttc tcaacagttt
    18721 ggacgcgtgc tagtcaacag ccatgtagct cagcctcttg cgcgtgcctg ccgtcagtgg
    18781 gtgggaagag atatcccttc cgcgcctgac tagcgtcatc cctgtccaag tatcctgacc
    18841 accatcaaag acctccgtag ttaaccagac gatttgatat ataagttcac ttgaaggata
    18901 gcaggaaata ggttcctgct tatgttcaat gaccctcttc acctcactat ctatatagtg
    18961 tttatcggca tatccctctt cacaagcagc gtcgctcgga gctttgaata gtaaccgcca
    19021 tgtctcaacg tacagcctta acagtagact gggggctccg ttcagatcta catactcgtc
    19081 tcgaccaatg ccatcaattt gctgcttcgc catatgcatc caccactgga ggagatccac
    19141 acgaggcatc aagccggagg tgctgagtaa ggtcgaggaa ctgcggccgt gctctggtat
    19201 gatacaagca agggataatg cagcaagaca actgacaaga tgattcttta catcatcagt
    19261 cactatttgt agtgggggtc tgcgcattcg agcagaccag cggtggttgt gaatcgggct
    19321 tatctggaca tcattccaga cacagcctct ggcttacgct gtgatatcct ccgcaagggc
    19381 tctcaggata gtgaggctcc gcatgatgct attataagca ttgttagggt ctgcacacca
    19441 taccagcgac tgaggctgtt acccggttac catttaaggc aactgcccgc ctaatctcac
    19501 cgcctcctgc ccgagatccc ctaaagtaaa caaactgctt cctccgtttc tgccttggtg
    19561 gaagcgaggg acatcaagtc tgcaccaatg gctttcatca acctgttgct gaccatttgc
    19621 ttaccggttg ttgtaagcgt tgtcgcatat ggactccatg cgctttacca acaccggtcc
    19681 aaaatcaacc ggctccgcaa acaaggcata gtaactagaa acttcacctt tactgagatg
    19741 cttgtgtggt tgacattgtg tttaggcgat gccaccagga tggaactggc taactggtca
    19801 catgtttgtc ctgtcggagt atctcaaccg tttgcccccc gatgccaacg ttgtgcttgc
    19861 gacgcaagag ttggcttggg aatacaccga cacagagatc ttcctcttgg atgtctggcc
    19921 catgtccccc gcacaataca tagtgttcta tccggaagca gcgtcacagg ctaccactaa
    19981 atttaacctc cccaaaacag ttatacatga ccggttcatg cgaccgatca caggcgggcc
    20041 tagtatgatt tctgtaggga acgctgagtg gaagccttgg agatcaatct tcaacccggg
    20101 gttcagtgca ggtagcatgc aggatcttct gcctgaagtt atcaaatcag tcagtgtctt
    20161 ttgcgataaa ctacgcgaaa aagccgattc tggagagatg tttgccttgg atgatctgac
    20221 caccagatta actatggatg tcatcctcaa agtgaccctg ttagtttatc ctccttgatt
    20281 ctcgggtcac ctgctaactc gtgcagtgat gccgatgttg accatcaaaa ttctgacaac
    20341 atcattgcaa ctgctcttgg tcaaatcact aaatggcatt cattctggga tccccgcgta
    20401 agggcaaacc cactacgccc tttagttcaa ggatactatg gccgcgtcgc ggacaaatgg
    20461 attcgtaaag cactggctga ccgattctcc gagatgaagc aagtgaaacg ggatgcatca
    20521 atccgttcca agcgtgccaa atcgattctc actctagcct tggaggcata cctagagaat
    20581 aaaaatgaag agatctctga ggcaacagag ttagatgacg acttcgccaa acatgtaaca
    20641 tatcagattc gactgttcct cttcgctgga aatgacacca cttcaagcag tatcgcctac
    20701 gtgtatcacc tcttgtccaa gcaccctgaa gctttgaccc aagtccggga agaacatgac
    20761 cgcatattcg gaccagatcc ttccgctgcg gtgcagctac tctgcgaaca gccttcactg
    20821 ctgaacaaat gtccatatac catggcagtc atcaaagaaa ctcttcggct ctataccccc
    20881 gcaagtacta tgcgtcaagg catcgatggt ttgtcactga ccgataggca cggcaatcgc
    20941 tatcccttgg cggatgatct cagcgtttcc gtcttacacc aggcggtaca tctcaaccca
    21001 agggtatggc cacgagcaag agagttcctc cccgaacggt ggctggtgga tgcagaccac
    21061 gaactatatc ccgatccagc cgcatatcgc ccgtttgagc aagggcctcg caactgcatt
    21121 ggtcagactc ttgtatacaa cgagatgcgg acagtcctag tgatgaccgc ccggacattt
    21181 gagatcaagc cagcatacga tgaatgggac gcaacgaagg cgaaacaaaa gggctggttt
    21241 gatcagattg ctgaatctgt agggttccag aacaagaagc ctaagctgtt acacggcgaa
    21301 agagcatatc agtctgagaa agccggcact c
//
