LOCUS       NKJJ01000020.1         46437 bp    DNA     linear   PLN 19-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   NKJJ01000020
VERSION     NKJJ01000020.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 06:54:43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1629874
            Orig. end    :: 1676311
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..46437
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[1644480:1645413](+),
                     [1645482:1645845](+), [1645945:1646617](+),
                     [1646677:1648224](+), [1648277:1651305](+),
                     [1651366:1651958](+), [1652013:1656578](+)}"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(14607..15539,15609..15971,16072..16743,16804..18350,
                     18404..21431,21493..22084,22140..26704)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     protocluster    1..46437
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[1644480:1645413](+),
                     [1645482:1645845](+), [1645945:1646617](+),
                     [1646677:1648224](+), [1648277:1651305](+),
                     [1651366:1651958](+), [1652013:1656578](+)}"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      join(14607..15539,15609..15971,16072..16743,16804..18350,
                     18404..21431,21493..22084,22140..26704)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
     cand_cluster    1..46437
                     /SMILES="C([*])C(-O)NC([*])C(=O)"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="(cds(Condensation and (AMP-binding or
                     A-OX)) or (Condensation and AMP-binding))"
                     /kind="chemical_hybrid"
                     /product="T1PKS"
                     /product="NRPS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..46437
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T1PKS"
                     /product="NRPS"
                     /region_number="4"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="(cds(Condensation and (AMP-binding or A-OX)) or
                     (Condensation and AMP-binding))"
                     /tool="antismash"
     mRNA            complement(join(1..571,638..1072,1099..1547))
                     /locus_tag="CAN33_52615"
                     /product="Flavin containing amine oxidoreductase family
                     protein"
     gene            complement(1..1547)
                     /locus_tag="CAN33_52615"
     CDS             complement(join(1..571,638..1072,1099..1547))
                     /codon_start=1
                     /db_xref="InterPro:IPR001613"
                     /db_xref="InterPro:IPR002937"
                     /db_xref="InterPro:IPR036188"
                     /db_xref="PFAM:PF01266"
                     /db_xref="PFAM:PF01593"
                     /db_xref="PFAM:PF13450"
                     /locus_tag="CAN33_52615"
                     /note="GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]; GO_process: GO:0055114 -
                     oxidation-reduction process [Evidence IEA]"
                     /product="Flavin containing amine oxidoreductase family
                     protein"
                     /protein_id="ncbi_CAN33_52615-T1"
                     /transl_table=1
                     /translation="MSRSSEGYLWTPKQATSGLPTDAVHPSTPALRTHYDVIVIGAGFA
                     GLIAARDLSRKHNLNVLLLEARDRIGGRTWTAKVLGEEIEMGGTWVHWNQPHLYAELHR
                     YGLHRNLKTSAGSFTPVDQWFKSSSGPVEKVSVGDYQATLERVAENRALMPYPHDSLRG
                     PAPWKRYDYLSVEERLEMSDLDGLSRWEKVLFASNVSTFGSAPVKDIGFVEALRWFALG
                     GHSMAGVFELAGVYKLGSGGMTSFARAILGEFTGHVSFGTVVEQIDHGRDMVEVVTKDG
                     RRVGARAVVSTVPLNCLNDIQFQPPLTPLRQAAITKGHINKGAKIHFKLRETLPGWFFT
                     AHDGSDSSFVFAFSDHNGTQLTGPSGTWCIGFGYNDQLTNKKDSKYILQRFKHDVNPDV
                     DIDAYATHDWMNDPYAKGAWACWGPNTASEYLEELQKPHGRVVFASADWADGWRGFVDG
                     AIERGQAAVGEVLGMLEGREGGRARL"
     mRNA            complement(join(3049..3984,4045..4803,4864..4889,
                     4949..4994))
                     /locus_tag="CAN33_52620"
                     /product="Fungal specific transcription factor domain
                     family protein"
     gene            complement(3049..4994)
                     /locus_tag="CAN33_52620"
     CDS             complement(join(3049..3984,4045..4803,4864..4889,
                     4949..4994))
                     /codon_start=1
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR021858"
                     /db_xref="InterPro:IPR036864"
                     /db_xref="PFAM:PF00172"
                     /db_xref="PFAM:PF11951"
                     /locus_tag="CAN33_52620"
                     /note="EggNog:ENOG41; GO_component: GO:0005634 - nucleus
                     [Evidence IEA]; GO_function: GO:0008270 - zinc ion binding
                     [Evidence IEA]; GO_function: GO:0000981 - DNA-binding
                     transcription factor activity, RNA polymerase II-specific
                     [Evidence IEA]; GO_process: GO:0006355 - regulation of
                     transcription, DNA-templated [Evidence IEA]"
                     /product="Fungal specific transcription factor domain
                     family protein"
                     /protein_id="ncbi_CAN33_52620-T1"
                     /transl_table=1
                     /translation="MSDPQPTSRRRFKTRNGCLRCKQRRIKCDETLPVCNQCTRKRFEC
                     PGYKRPLKWSSKYEVGRSGNNSAVLSSSEQVLQRIEPVQPLRPILFQSTVPDDATRSLP
                     VQTDVQPAQNETAVGSDQASISAANSSPPKDIWIPSTMVGNDCGELWTGTILAEPTLST
                     QKDDDAALLRHYFSNVCRVNSCFDSHKNFFRAEVGSLISSRPLIHYCVLSMSAAHLTAR
                     QRDMLTITLRHRTEALSCLKARITQGVLTQEINNGSPLDNVAEILIGSILLGMTEGWHD
                     PTQLGVTHLRGARTLFRKWITTVPACCPRTRTMITGIMSYWEAVASFVHNQSLDSISYL
                     MPFSFETCHVYVNPWTGICTPLFIHLAQIGILTRQRSLARQLPVGFWGHVGPDMLERAK
                     AIEDALQSYRTLSIHQIEDTADSRTPVDHLQRIASIYRLVGLLQLYMTFPELHGAHSVD
                     FSLTHSILGLATNVLTTIGVLPHTSGVYCLLTIPLIIAGSALQLPCFSSDVPTSMLQQD
                     TYLFWRNFVRERVKTVQEIVGLVTIGRAQKILDKVWFLADMRRAAEDPDQEWEYIQWTE
                     VMSSENLESIFG"
     mRNA            join(5400..5498,5575..5767,5818..5872,5929..6020,
                     6081..6452,6509..6829,6881..7332)
                     /locus_tag="CAN33_52625"
                     /product="Amino acid permease family protein"
     gene            5400..7332
                     /locus_tag="CAN33_52625"
     CDS             join(5400..5498,5575..5767,5818..5872,5929..6020,
                     6081..6452,6509..6829,6881..7332)
                     /codon_start=1
                     /db_xref="InterPro:IPR002293"
                     /db_xref="PFAM:PF00324"
                     /db_xref="PFAM:PF13520"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038:phenylalanine-specific permease (Score: 229.6;
                     E-value: 8.9e-70)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_52625"
                     /note="EggNog:ENOG41; GO_component: GO:0016020 - membrane
                     [Evidence IEA]; GO_function: GO:0022857 - transmembrane
                     transporter activity [Evidence IEA]; GO_process: GO:0055085
                     - transmembrane transport [Evidence IEA]"
                     /product="Amino acid permease family protein"
                     /protein_id="ncbi_CAN33_52625-T1"
                     /transl_table=1
                     /translation="MSPSMKAPADTMTAKSADEGENELRIGEAIPIKKPFSRLTIFSLT
                     VVLMSTWEALSRYSPTFTIQHHNLVSDHTIHDSTMSSGLVSGGPVSLIYGFILAIVGSM
                     ATAASLGEMVSMYPTAGGQYHFIAKFAPDKWQNILSWFVGWIGTFGWVSFTASAPYLAA
                     GMIQGLVVLTCEAYQPQRWHLSLIYWALVGFATALNIWGSRLFSLVETASLVIHLVGFV
                     VVLIVMWVCVPAKHNATFVFTTFLNSTGWSSNGLAWCLGMLSSCYVLAGYDGAIHLCEE
                     MVNPETAVPYCMLGSLTINDILGFVFLLTILFCMGDMENALDTPTNYPIIEIFRSVTGS
                     SAGSCALTAVLIIAAWLGTIALLASTARMVLSLARDRALPFSGYLSQLDTHTDLPKRAI
                     ITTSSLLVLFGLINIASTTAFNAILSLAVLGLHISYLVPILFFLWRRLSAPHSLSYGPW
                     RLGRAGVAINVIAIIYLLFTSIFMVFPSYQPVTPSNMNYASLIFGFVWLMSVVFWIVRG
                     RKEYDGPAVL"
     mRNA            complement(join(8111..9536,9645..9778))
                     /locus_tag="CAN33_52630"
                     /product="major facilitator superfamily protein"
     gene            complement(8111..9778)
                     /locus_tag="CAN33_52630"
     CDS             complement(join(8111..9536,9645..9778))
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 300.8; E-value:
                     2.2e-91)"
                     /gene_kind="transport"
                     /locus_tag="CAN33_52630"
                     /note="SECRETED:SignalP(1-23); EggNog:ENOG41; GO_component:
                     GO:0005887 - integral component of plasma membrane
                     [Evidence IEA]; GO_process: GO:0055085 - transmembrane
                     transport [Evidence IEA]"
                     /product="major facilitator superfamily protein"
                     /protein_id="ncbi_CAN33_52630-T1"
                     /transl_table=1
                     /translation="MAARGWRFWLIIAGLSITSLLTAIECTVPSTALPTISRDLNAGES
                     TAVQPLFGQLADVFGRRWPLISAVAFFALGSGISGGASSTAMLIAGRTIQGVGLGGVNM
                     LIDVVVCDLVPLRERGQVTALIFVVFAVGSSIGPFIGGAFTQHVTWRWAFYISLPIAGS
                     AMVFMILFLQVKSQKHTTFADKMKRIDWLGNTILVAAVVAVLIALSFGGTSYPWSSWRV
                     IVPLVLGLIGLIAFALVQVTPKLCPEPTMPPRLFANRTTFAAFVISFLHGMLMYWELYF
                     LPVYFQGVQLSTSTRSGVELLPTVIVTVPAAIVAGALVTKTGRYKPIQISGFAFMALGM
                     GLFSLLDQNSSTGAWVGYQLLAAIGSGFIVTSTLPAAQAALSEADVATSTATWAFCRAF
                     GAVWGVSIPAAIFNNRFAAQVSAQNDTGHAAQVLQNTGNAYQQASREFVMQFSPEVQSM
                     IIDAYTAALQRVWQISVVFAGLGFLFAWLEKEVELRTTLETEYGPEKKEPSPEVEDVTV
                     SK"
     mRNA            complement(join(10394..11272,11361..11624))
                     /locus_tag="CAN33_52635"
                     /product="hypothetical protein"
     gene            complement(10394..11624)
                     /locus_tag="CAN33_52635"
     CDS             complement(join(10394..11272,11361..11624))
                     /codon_start=1
                     /locus_tag="CAN33_52635"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CAN33_52635-T1"
                     /transl_table=1
                     /translation="MATSSTAGEVDALLSDHSTSNRGPEMLGACITSMIFCVIGLSIRV
                     WAQSLIHRIWTADCILIILAAIFTLATAGCVIAAVASGMGQHAYWVISEDPHPPERMAF
                     VVEMSYIITIIQAPALMFTKLSVLVFYQRAFSTIVRGVRWTIWGLFAFCLGLGVASTIV
                     FVCACLPPQMFWLRVYPIFGYEAPQPLEDYTCMPQRTHLCIPLLLDSFSELILLGIPAV
                     VLWNLQMALRRKIIIIFTFSLGLFVTAISAVRFYYAWTMVLGGDMTWADTDTCIWTTVQ
                     LCFGIVTACIPASAPLLRLRQTPNPRPWNKQGGYMLSINYASNSRKRKDMGTESMLDLQ
                     RSPEDDVEDSATRGTSWETPPSHELRKIEVVRKVEIHHGP"
     mRNA            12082..13131
                     /locus_tag="CAN33_52640"
                     /product="Zinc-binding dehydrogenase family protein"
     gene            12082..13131
                     /locus_tag="CAN33_52640"
     CDS             12082..13131
                     /NRPS_PKS="Domain: PKS_ER (19-218). E-value: 5.8e-28.
                     Score: 89.6. Matches aSDomain:
                     nrpspksdomains_CAN33_52640_PKS_ER.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="InterPro:IPR020843"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF08240"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 208.2; E-value: 3e-63)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="CAN33_52640"
                     /note="EggNog:ENOG41; GO_function: GO:0016491 -
                     oxidoreductase activity [Evidence IEA]; GO_process:
                     GO:0055114 - oxidation-reduction process [Evidence IEA]"
                     /product="Zinc-binding dehydrogenase family protein"
                     /protein_id="ncbi_CAN33_52640-T1"
                     /transl_table=1
                     /translation="MILPDSQYALVVQGPGSLQLLSHAPVPSLGADQVLIEVKGVALNP
                     SDWKMLDTAAANPGTISGGDFAGVVVACGREVTEAAIGDRLCGFVFGAASSGAFAQFVM
                     VHPSLCFRIPPSMSFEAAASLGLGLMTGGLMLQSLHLNPLRAAESTPDHWVLVYGGSTA
                     TGTLAIQLLRYHGYRVITTCSPRNFELVRRVGAVATFDYTSPTCKEDIRAYTGGTLMHV
                     MDCIADSRATTICYGAIGEAGGRYCALNQFPAQLHRRRASVSPEWIHSATIFGGDVQLA
                     GSYYRTARPEDREFAIEWARYCTELLAQGKLQPHPLQVQQGGLARVVEDLVLLRNQQIT
                     GKKLVYPLY"
     aSDomain        12139..12735
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_52640_PKS_ER.1"
                     /evalue="5.80E-28"
                     /label="CAN33_52640_PKS_ER.1"
                     /locus_tag="CAN33_52640"
                     /score="89.6"
                     /tool="antismash"
                     /translation="LLSHAPVPSLGADQVLIEVKGVALNPSDWKMLDTAAANPGTISGG
                     DFAGVVVACGREVTEAAIGDRLCGFVFGAASSGAFAQFVMVHPSLCFRIPPSMSFEAAA
                     SLGLGLMTGGLMLQSLHLNPLRAAESTPDHWVLVYGGSTATGTLAIQLLRYHGYRVITT
                     CSPRNFELVRRVGAVATFDYTSPTCKEDIRAYTGGTL"
     mRNA            complement(join(13281..13619,13694..13849))
                     /locus_tag="CAN33_52645"
                     /product="EthD domain family protein"
     gene            complement(13281..13849)
                     /locus_tag="CAN33_52645"
     CDS             complement(join(13281..13619,13694..13849))
                     /codon_start=1
                     /db_xref="InterPro:IPR009799"
                     /db_xref="InterPro:IPR011008"
                     /db_xref="PFAM:PF07110"
                     /locus_tag="CAN33_52645"
                     /note="EggNog:ENOG41"
                     /product="EthD domain family protein"
                     /protein_id="ncbi_CAN33_52645-T1"
                     /transl_table=1
                     /translation="MAPQKQLVLKLTSFRYKKEGISWKDFHEYGTRQHAPKAARIQERH
                     GAYKITHVYTPPITKSLITDKIPWAVRPGWIVDDHDVSVSMYVPDPETLQAIVTDPEFQ
                     SLVAGEDHILDQERATVTAGWEEVFVDEGKIVDIDRESWEAFTAMGQGSKKTDAPEDVR
                     I"
     mRNA            join(14607..15539,15609..15971,16072..16743,16804..18350,
                     18404..21431,21493..22084,22140..26704)
                     /locus_tag="CAN33_52650"
                     /product="AMP-binding enzyme family protein"
     gene            14607..26704
                     /locus_tag="CAN33_52650"
     CDS             join(14607..15539,15609..15971,16072..16743,16804..18350,
                     18404..21431,21493..22084,22140..26704)
                     /NRPS_PKS="Domain: PKS_KS (8-437). E-value: 2.4e-169.
                     Score: 555.4. Matches aSDomain:
                     nrpspksdomains_CAN33_52650_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (557-872). E-value: 9.8e-86.
                     Score: 279.4. Matches aSDomain:
                     nrpspksdomains_CAN33_52650_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (946-1126). E-value: 3.9e-19.
                     Score: 61.3. Matches aSDomain:
                     nrpspksdomains_CAN33_52650_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (2031-2205). E-value: 4.6e-52.
                     Score: 168.2. Matches aSDomain:
                     nrpspksdomains_CAN33_52650_PKS_KR.1"
                     /NRPS_PKS="Domain: Condensation_LCL (2468-2755). E-value:
                     1.4e-43. Score: 140.7. Matches aSDomain:
                     nrpspksdomains_CAN33_52650_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (2920-3305). E-value:
                     4.6e-79. Score: 257.5. Matches aSDomain:
                     nrpspksdomains_CAN33_52650_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (3427-3495). E-value: 3.4e-12.
                     Score: 38.1. Matches aSDomain:
                     nrpspksdomains_CAN33_52650_PCP.1"
                     /NRPS_PKS="Domain: TD (3537-3775). E-value: 1.3e-48. Score:
                     157.0. Matches aSDomain: nrpspksdomains_CAN33_52650_TD.1"
                     /NRPS_PKS="type: Hybrid PKS-NRPS"
                     /codon_start=1
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR018201"
                     /db_xref="InterPro:IPR020801"
                     /db_xref="InterPro:IPR020806"
                     /db_xref="InterPro:IPR020807"
                     /db_xref="InterPro:IPR020841"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR023213"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="InterPro:IPR032821"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="InterPro:IPR036736"
                     /db_xref="InterPro:IPR042099"
                     /db_xref="InterPro:IPR042104"
                     /db_xref="PFAM:PF00106"
                     /db_xref="PFAM:PF00109"
                     /db_xref="PFAM:PF00501"
                     /db_xref="PFAM:PF00550"
                     /db_xref="PFAM:PF00668"
                     /db_xref="PFAM:PF00698"
                     /db_xref="PFAM:PF01370"
                     /db_xref="PFAM:PF02801"
                     /db_xref="PFAM:PF07993"
                     /db_xref="PFAM:PF08659"
                     /db_xref="PFAM:PF13561"
                     /db_xref="PFAM:PF14765"
                     /db_xref="PFAM:PF16197"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 231.8; E-value:
                     2.4e-70)"
                     /gene_kind="biosynthetic"
                     /locus_tag="CAN33_52650"
                     /note="GO_function: GO:0031177 - phosphopantetheine binding
                     [Evidence IEA]; GO_function: GO:0016740 - transferase
                     activity [Evidence IEA]; GO_function: GO:0003824 -
                     catalytic activity [Evidence IEA]"
                     /product="AMP-binding enzyme family protein"
                     /protein_id="ncbi_CAN33_52650-T1"
                     /sec_met_domain="Condensation (E-value: 2.6e-34, bitscore:
                     114.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.3e-79, bitscore:
                     262.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.2e-15, bitscore:
                     51.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.4e-84, bitscore: 279.4,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 5.7e-171, bitscore:
                     565.1, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 4.1e-42, bitscore:
                     140.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.8e-35, bitscore:
                     118.4, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MAYPQAEPVAIIGSACRFPGANSPEELWNLLLRPRDLSKKIPEDR
                     FSAAGFWNAVGSHHGTSNVTHSYFLEGDSRRFDANFFNINPREAASIDPQHRLLLETVY
                     EALESAGLSLEAMCGTNTGVYAGLMCADYLDLQLRDPDTIAQYHATGTARSILSNRVSY
                     FFDWKGPSMTIDTACSSSLVAVHLAVQALRHSECSTAIAAGANLILGPEMYIAESNLHM
                     LSPTGTSKMWDADANGYARGEGIGVVVLKRLGDALRAGDPIECVIRETAVNSDGRTNGI
                     TMPLATSQSSLIQETYRKAGLNPLSELDRHAHGTGTPVGDPLEAEAIKCAFFPDQHPAC
                     AEPPRHLLNVGSVKTVIGHTEGAAGIAGLLKASLALQNGVVPPNLHFNRLNPKIAPFYA
                     NLHVPTVPLSWPKVEVARASVNSFGFGGTNAHCILERYTPSVHGVQQLLPMCGSSLATT
                     AQHESPLIFPLSACSQRSLTRLVQRYAAYIAANPSVDLQNVAFTVRSRSALSAKHCFVA
                     LSRGSLIEQLSSYTAPSHSIGQGAHAQLARVTAGVPRVLGIFTGQGAQWPTMGRNLILR
                     SPVFAATIERLDIVLGRVPNPPDWCLRDELLADAGSSRCSDSEFSQPLCTAVQIALVDL
                     LHSVGVRFNVVVGHSSGEIAAAYTAGCLSAEEAITVAYYRGYYSHRASSTTGAKLSMMA
                     AGIGFAEALRMCDRAEYKGKIFPAASNAPFSTTISGDEKSLHQALSELASQERFARMLR
                     VDKAYHTPYMRPCALPYLNSLHQSNVQGRIGDPSCTWISSVHGFEMDMSSDPVNSDYWV
                     ENLLQPVLFSEALGQAIRDHGPFSLALEVGPHPAMKGPTGQNLKAFGHNEIPYHGSLTR
                     GEDDTLALGQCLASVWATFGPSAVNLSKLASSLGGEAASRPLRIMKALPTYPWDHETIH
                     WRESRRSKQYCSRPAPHELLGACTERSEGQICWRNIFHVHEISWLRDHKVHGEVVFPAA
                     GYCVMAIEAAMAFLAQPIRLIELQQLVIHRGVRIEDNSIGTEMISTLSLAPTGNGSRSS
                     PDLSTAAFNFSLTAGKADGTEQSSIRFETKISVTLGNPHIATLPASQRNSAEWPAADVD
                     RFYLSMQEIGLEYTGVFRSMTSCERRWKKASARIAPIPSSMIIHPGFLDTTFQTLFLGM
                     AAPGDESLRTTYLPTKIQSIRVNPAILEDGSPVAMPYHIDTTITDLHCPTQESQASFTG
                     DVDVYSDGNCVIQIEGLACVALGSLTKADDRNMFHTTTWELDILCGMSASRVSPESEYL
                     ALLEEYESIARQYVEGRCVSSSTLSSPTSPGEQLIDALHAGRNNHHTNGIENRSHSRDY
                     WQSGVGPQRIRKYLAQTAKQIAHKHPQMTIMQLIHVSDDEGSAVRMILDSLEDSFASYV
                     VTGLSEDVLRHAQACVATPDERVRFDVFDTFQRSVNGDSEQGFDLVIANLGQSPESDKA
                     HQVLNSVRQLLRPGGYVLLQAVTGRGLFPGLILDNLVGHSSGPMARSEATWERTLRNLG
                     YSGIQSMVYDSGMAHPHCHSLILSQAMTPSLSQILRPSIALDPLSSEEKILIIGGETAL
                     GSRVVRELQPLLRPWKNSILILPSLTDIASFDSHVAKHVLCLADFEAPIFRDFSPLHFD
                     ALQKLFQQPRNVFLVTRGFKQGDPYSSMTVGLARVLRTELPSSNVVLLDVDRDDNLDTA
                     QLATLFGQFISGIQLQSDDTRTLLKQELEMALENGDLYIPRIKHAKDMNDRFNSAFRQI
                     PATHQPQLTAQLNVPFEKPVPIRVLCRSSSALMVDDDASYFLCLGKARLGNLEQCVLAF
                     TPSADDLVFLEELSLLQCNIDKDMAPKVLPAVIGFYISARIQKFASSGRTVIFTNEPLL
                     ARALVSTVEETEHISITLATSNLSIALWHESIAYWHPYTATRNIKHLLPPDIDLFINLE
                     KEPNSLCDRVLNALSSKCTIRGREHFFSAHARQPQSGLSRSYKEYLQFLWSQYNGHANS
                     LPPATEIESLGATEVCAIEQYRSETLVRRLDARAFFRDDATYFLVGMTGELGHSLARWM
                     VAHGVRYLAIASRSPKPARWYQELEEQGCQVLVLSLDVCDREDLQRVHAQIHRAMPPIA
                     GIVNGAMVLADGAFVNMSYEDFVRVLEPKVKGTENLDQLYNQPGLDFFILLSSTATLIG
                     NSGQSNYSVANMYMQGVARRRQQRGLAGSCVDIGMVLGLGVVTRNVTHEKTLRKAGLLA
                     ISETDFHCIFAEAMRVGWEGVTDSPCFSTGLHVPPGQSRPQWYDDPRFAHFHVMEDLDS
                     KSQHRTRTQLLQDRLRNPVEMAVAESWIQEAFITMLQKLLQLPGPITNITQPLTQLGID
                     SLLSTEIKGWFYKELNFHVSVLKLLGGTSIIEICREATECFFQAESLYMNVSYEPKAVV
                     TTPTRNSEQIQEETESYADQSEGSSSDQGTSRASQFTPASTLDFTPQAVDDPQSSSTLS
                     LRNLLPLSVEQEKMYFMLATVDDPTMYNCTIQYELHGNLDMERFKIAVIHVAQRHESLR
                     TAFVTQAADGMPRRAILEISQIGWWERTSGDPLEASLEFSRVHSHEYDLAKGQSMVISI
                     LHTSLQHHIMTFGYHHLIMDGVSWQLLLREFAAAYQDPDLLAPVISQYSAFCDEALMRA
                     ASRNDALERPRLLETASPLPLFPFARVSFRQVHTCYETIQVSSQLDAGTSAKVKAVSSR
                     TGATSFHFHVAAIQLLIQKVLDIGKFMMGITNANRDNPRFEKVIGHMVEVVPLCCEPQS
                     SCTFTDLLQDTRARVLAALASPSASQKPMSAEQMHTTECNVAVNYIAKFTQDIRFDQST
                     LKYSTSQLARQPYDLVFTIRENEDGTMLLNFEAQKYLYYEKDLRILMSLYTQLTETFSM
                     GTESRLESYECIAASGMPSLHLQQGPVLDHPWSGCLTKRIRKTITTYPADLAIKDDSGM
                     RLTYETMHSRSLSIMQILLEAGVSFGTPVAVACGPSVDTVCTLLAIWWIGAIYMPVDLM
                     QGHQRLAHIIDASRPAAIVCKGPLGQLETSHIAPVIQLPQVLQPTTLGHQDYADENSPA
                     ALLHTSGSTGVPKGVLLSHRNLRCHFNATEQAFPIGRQVVLQHSSHSFDAGLFQILLAL
                     LHGGTLVITNNLKEPGQLAELMLREHVSVVTAVPSEYALWIGEAGQLLSELGSWRFAFC
                     VGEKLSRATIQAFVSLGLPDLTLINAYGPCETTMACTMGVIDYERVDGDSQSVSIGEPL
                     SSYGIAILNSQLKSVPQGWPGEICIAGAAVALGYLDVKDEEGRFVELDGVRVYRTGDRG
                     RLREDGSLEYLGRVDGDSQLKLRGIRLELDEISNALLQASAGALVDAATIAKGDPDDLY
                     LVSFVVLSRAVEIEDNIDLFIKQLLNTVALPPHAKPAQVSIVTRIPLTSSGKVDRKALG
                     RLPVGQSGSSSEQPVLEIIERKLLEMWKEYLPSTGLPITRETSFFELGGNSLRLLKLQA
                     RIRRVTGISIPITELFQSSTLGEMARLAGTVVTRIRASSKAIDWDSETAIPDYLDQIKP
                     LPTQPNGAVREVILTGATGYYGRAILEALVEIPSVARIHCIAIRPAPDGSPRQELPVKS
                     SKICLYSGDLSDPTCGLNAVDIDKLTRTVDCVIHNGADVSFVKPYAALRKANVLSTKYL
                     FSLCLARRISFHYISTASVTSLSERDTFSAASVAGFPPPSFNNDGHNPLVSGYVASKWA
                     SEVFLERACARFSDLMPDVHIYRPTSITTASSPHESPSDASAGDTNIIGAILDVSRFLH
                     AVPDTRDWRGYIDLIGLNGAVESLVRNITTTRSTALPSALNEASKENDGLPCQIRYMNV
                     CGETRFKASELREFMEGSDQAAYLQLPWGVWLEKARAGEVIDAGVADFLGEWEAATAAD
                     YWRTSPSSARSPFLLPWLE"
     aSDomain        join(14631..15539,15609..15971,16072..16086)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_52650_PKS_KS.1"
                     /evalue="2.40E-169"
                     /label="CAN33_52650_PKS_KS.1"
                     /locus_tag="CAN33_52650"
                     /score="555.4"
                     /tool="antismash"
                     /translation="VAIIGSACRFPGANSPEELWNLLLRPRDLSKKIPEDRFSAAGFWN
                     AVGSHHGTSNVTHSYFLEGDSRRFDANFFNINPREAASIDPQHRLLLETVYEALESAGL
                     SLEAMCGTNTGVYAGLMCADYLDLQLRDPDTIAQYHATGTARSILSNRVSYFFDWKGPS
                     MTIDTACSSSLVAVHLAVQALRHSECSTAIAAGANLILGPEMYIAESNLHMLSPTGTSK
                     MWDADANGYARGEGIGVVVLKRLGDALRAGDPIECVIRETAVNSDGRTNGITMPLATSQ
                     SSLIQETYRKAGLNPLSELDRHAHGTGTPVGDPLEAEAIKCAFFPDQHPACAEPPRHLL
                     NVGSVKTVIGHTEGAAGIAGLLKASLALQNGVVPPNLHFNRLNPKIAPFYANLHVPTVP
                     LSWPKVEVARASVNSFGFGGTNAHCILERYT"
     CDS_motif       15111..15158
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0001"
                     /evalue="5.00E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="CAN33_52650"
                     /score="21.5"
                     /tool="antismash"
                     /translation="GPSMTIDTACSSSLVAV"
     CDS_motif       15300..15338
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0002"
                     /evalue="7.30E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="CAN33_52650"
                     /score="12.7"
                     /tool="antismash"
                     /translation="WDADANGYARGEGI"
     CDS_motif       16447..16497
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0003"
                     /evalue="8.90E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="CAN33_52650"
                     /score="15.1"
                     /tool="antismash"
                     /translation="IFTGQGAQWPTMGRNLIL"
     aSDomain        join(16447..16743,16804..17451)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_52650_PKS_AT.1"
                     /evalue="9.80E-86"
                     /label="CAN33_52650_PKS_AT.1"
                     /locus_tag="CAN33_52650"
                     /score="279.4"
                     /specificity="Minowa: mmal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="consensus: pk"
                     /tool="antismash"
                     /translation="IFTGQGAQWPTMGRNLILRSPVFAATIERLDIVLGRVPNPPDWCL
                     RDELLADAGSSRCSDSEFSQPLCTAVQIALVDLLHSVGVRFNVVVGHSSGEIAAAYTAG
                     CLSAEEAITVAYYRGYYSHRASSTTGAKLSMMAAGIGFAEALRMCDRAEYKGKIFPAAS
                     NAPFSTTISGDEKSLHQALSELASQERFARMLRVDKAYHTPYMRPCALPYLNSLHQSNV
                     QGRIGDPSCTWISSVHGFEMDMSSDPVNSDYWVENLLQPVLFSEALGQAIRDHGPFSLA
                     LEVGPHPAMKGPTGQNLKAFGHNEIPYHGSLTRGE"
     CDS_motif       join(16693..16743,16804..16854)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0004"
                     /evalue="1.10E-09"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="CAN33_52650"
                     /score="30.8"
                     /tool="antismash"
                     /translation="GVRFNVVVGHSSGEIAAAYTAGCLSAEEAITVAYY"
     CDS_motif       17284..17346
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0005"
                     /evalue="5.70E-01"
                     /label="C2_starter_024-063"
                     /locus_tag="CAN33_52650"
                     /score="3.0"
                     /tool="antismash"
                     /translation="QPVLFSEALGQAIRDHGPFSLA"
     aSDomain        17674..18213
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_52650_PKS_DH.1"
                     /evalue="3.90E-19"
                     /label="CAN33_52650_PKS_DH.1"
                     /locus_tag="CAN33_52650"
                     /score="61.3"
                     /tool="antismash"
                     /translation="HELLGACTERSEGQICWRNIFHVHEISWLRDHKVHGEVVFPAAGY
                     CVMAIEAAMAFLAQPIRLIELQQLVIHRGVRIEDNSIGTEMISTLSLAPTGNGSRSSPD
                     LSTAAFNFSLTAGKADGTEQSSIRFETKISVTLGNPHIATLPASQRNSAEWPAADVDRF
                     YLSMQEIGLEYTGVFRSM"
     CDS_motif       17755..17832
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0006"
                     /evalue="6.30E-15"
                     /label="PKSI-DH_m2"
                     /locus_tag="CAN33_52650"
                     /score="47.4"
                     /tool="antismash"
                     /translation="WLRDHKVHGEVVFPAAGYCVMAIEAAM"
     CDS_motif       19599..19649
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0007"
                     /evalue="1.20E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="CAN33_52650"
                     /score="-1.2"
                     /tool="antismash"
                     /translation="LIIGGETALGSRVVRELQ"
     aSDomain        join(20982..21431,21493..21564)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_52650_PKS_KR.1"
                     /evalue="4.60E-52"
                     /label="CAN33_52650_PKS_KR.1"
                     /locus_tag="CAN33_52650"
                     /score="168.2"
                     /specificity="KR stereochemistry: (unknown)"
                     /specificity="KR activity: active"
                     /tool="antismash"
                     /translation="ATYFLVGMTGELGHSLARWMVAHGVRYLAIASRSPKPARWYQELE
                     EQGCQVLVLSLDVCDREDLQRVHAQIHRAMPPIAGIVNGAMVLADGAFVNMSYEDFVRV
                     LEPKVKGTENLDQLYNQPGLDFFILLSSTATLIGNSGQSNYSVANMYMQGVARRRQQRG
                     LAGSCVDIGMVL"
     CDS_motif       20985..21083
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0008"
                     /evalue="5.30E-13"
                     /label="PKSI-KR_m1"
                     /locus_tag="CAN33_52650"
                     /score="41.5"
                     /tool="antismash"
                     /translation="TYFLVGMTGELGHSLARWMVAHGVRYLAIASRSP"
     CDS_motif       join(21351..21431,21493..21522)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0009"
                     /evalue="1.30E-16"
                     /label="PKSI-KR_m4"
                     /locus_tag="CAN33_52650"
                     /score="53.1"
                     /tool="antismash"
                     /translation="LDFFILLSSTATLIGNSGQSNYSVANMYMQGVARRRQQ"
     aSDomain        22409..23269
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_52650_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.40E-43"
                     /label="CAN33_52650_Condensation_LCL.1"
                     /locus_tag="CAN33_52650"
                     /score="140.7"
                     /tool="antismash"
                     /translation="LPLSVEQEKMYFMLATVDDPTMYNCTIQYELHGNLDMERFKIAVI
                     HVAQRHESLRTAFVTQAADGMPRRAILEISQIGWWERTSGDPLEASLEFSRVHSHEYDL
                     AKGQSMVISILHTSLQHHIMTFGYHHLIMDGVSWQLLLREFAAAYQDPDLLAPVISQYS
                     AFCDEALMRAASRNDALERPRLLETASPLPLFPFARVSFRQVHTCYETIQVSSQLDAGT
                     SAKVKAVSSRTGATSFHFHVAAIQLLIQKVLDIGKFMMGITNANRDNPRFEKVIGHMVE
                     VVPLCCE"
     CDS_motif       22469..22585
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0010"
                     /evalue="4.10E-12"
                     /label="C2_LCL_024-062"
                     /locus_tag="CAN33_52650"
                     /score="38.5"
                     /tool="antismash"
                     /translation="TMYNCTIQYELHGNLDMERFKIAVIHVAQRHESLRTAFVT"
     CDS_motif       22790..22855
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0011"
                     /evalue="2.90E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="CAN33_52650"
                     /score="26.3"
                     /tool="antismash"
                     /translation="YHHLIMDGVSWQLLLREFAAAYQ"
     CDS_motif       23189..23263
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0012"
                     /evalue="2.30E-04"
                     /label="C5_LCL_267-296"
                     /locus_tag="CAN33_52650"
                     /score="13.7"
                     /tool="antismash"
                     /translation="GITNANRDNPRFEKVIGHMVEVVPLC"
     aSDomain        23765..24919
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_52650_AMP-binding.1"
                     /evalue="4.60E-79"
                     /label="CAN33_52650_AMP-binding.1"
                     /locus_tag="CAN33_52650"
                     /score="257.5"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="ITTYPADLAIKDDSGMRLTYETMHSRSLSIMQILLEAGVSFGTPV
                     AVACGPSVDTVCTLLAIWWIGAIYMPVDLMQGHQRLAHIIDASRPAAIVCKGPLGQLET
                     SHIAPVIQLPQVLQPTTLGHQDYADENSPAALLHTSGSTGVPKGVLLSHRNLRCHFNAT
                     EQAFPIGRQVVLQHSSHSFDAGLFQILLALLHGGTLVITNNLKEPGQLAELMLREHVSV
                     VTAVPSEYALWIGEAGQLLSELGSWRFAFCVGEKLSRATIQAFVSLGLPDLTLINAYGP
                     CETTMACTMGVIDYERVDGDSQSVSIGEPLSSYGIAILNSQLKSVPQGWPGEICIAGAA
                     VALGYLDVKDEEGRFVELDGVRVYRTGDRGRLREDGSLEYLGRVDG"
     CDS_motif       24167..24223
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0013"
                     /evalue="1.60E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="CAN33_52650"
                     /score="20.6"
                     /tool="antismash"
                     /translation="ALLHTSGSTGVPKGVLLSHR"
     CDS_motif       24743..24805
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0014"
                     /evalue="1.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="CAN33_52650"
                     /score="20.4"
                     /tool="antismash"
                     /translation="PQGWPGEICIAGAAVALGYLDV"
     CDS_motif       24902..24970
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0015"
                     /evalue="3.50E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="CAN33_52650"
                     /score="13.4"
                     /tool="antismash"
                     /translation="YLGRVDGDSQLKLRGIRLELDEIS"
     aSDomain        25286..25489
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_52650_PCP.1"
                     /evalue="3.40E-12"
                     /label="CAN33_52650_PCP.1"
                     /locus_tag="CAN33_52650"
                     /score="38.1"
                     /tool="antismash"
                     /translation="ERKLLEMWKEYLPSTGLPITRETSFFELGGNSLRLLKLQARIRRV
                     TGISIPITELFQSSTLGEMARLAG"
     CDS_motif       25595..25654
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAN33_52650_0016"
                     /evalue="5.90E+00"
                     /label="NRPS-A_a6"
                     /locus_tag="CAN33_52650"
                     /score="-0.4"
                     /tool="antismash"
                     /translation="PNGAVREVILTGATGYYGRAI"
     aSDomain        25616..26329
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAN33_52650_TD.1"
                     /evalue="1.30E-48"
                     /label="CAN33_52650_TD.1"
                     /locus_tag="CAN33_52650"
                     /score="157.0"
                     /tool="antismash"
                     /translation="VILTGATGYYGRAILEALVEIPSVARIHCIAIRPAPDGSPRQELP
                     VKSSKICLYSGDLSDPTCGLNAVDIDKLTRTVDCVIHNGADVSFVKPYAALRKANVLST
                     KYLFSLCLARRISFHYISTASVTSLSERDTFSAASVAGFPPPSFNNDGHNPLVSGYVAS
                     KWASEVFLERACARFSDLMPDVHIYRPTSITTASSPHESPSDASAGDTNIIGAILDVSR
                     FLHAVPDTRDWRGYIDL"
     mRNA            join(35041..35170,35242..35426,35524..35687,35742..36000,
                     36064..36357,37215..37656,37732..38025,38073..38428)
                     /locus_tag="CAN33_52655"
                     /product="G-protein alpha subunit family protein"
     gene            35041..38428
                     /locus_tag="CAN33_52655"
     CDS             join(35041..35170,35242..35426,35524..35687,35742..36000,
                     36064..36357,37215..37656,37732..38025,38073..38428)
                     /codon_start=1
                     /db_xref="InterPro:IPR001019"
                     /db_xref="InterPro:IPR002975"
                     /db_xref="InterPro:IPR011025"
                     /db_xref="InterPro:IPR013177"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="PFAM:PF00025"
                     /db_xref="PFAM:PF00503"
                     /db_xref="PFAM:PF08213"
                     /locus_tag="CAN33_52655"
                     /note="GO_component: GO:0005834 - heterotrimeric G-protein
                     complex [Evidence IEA]; GO_function: GO:0003924 - GTPase
                     activity [Evidence IEA]; GO_function: GO:0031683 -
                     G-protein beta/gamma-subunit complex binding [Evidence
                     IEA]; GO_function: GO:0019001 - guanyl nucleotide binding
                     [Evidence IEA]; GO_function: GO:0005525 - GTP binding
                     [Evidence IEA]; GO_function: GO:0001664 - G protein-coupled
                     receptor binding [Evidence IEA]; GO_process: GO:0007186 - G
                     protein-coupled receptor signaling pathway [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /product="G-protein alpha subunit family protein"
                     /protein_id="ncbi_CAN33_52655-T1"
                     /transl_table=1
                     /translation="MGCMSSKPVDTADKDAVQRSARIEKVLKNDKKVMDRTIKILLLGA
                     GESGKSTIIKQMRIIHSGGFPEDERRQTRAVIYSNLVIAFKVLLDIMRAENIDFQLEKT
                     KPLAEYVDKLEPDVGSDEAFSDLKVRDALRDMWDDTGVQKAVARGHEFALHDNLHYFFD
                     SLDRIFTPGWLPDNQDMLQARLRTTGITETLFELGQMNFRMMDVGGQRSERKKWIHCFE
                     GVQCLLFMVALSGYDQCLVEDQNANQMHEAMMLFESLVNGEWFKRKPIILFLNKIDLFK
                     GKLHVSPVSNHFPDYNGSNTDFDAAARYFADRFRGINRIPDREIYIHYTNATDTTLLKA
                     TMDSFRMIGSNFDFASSFPTTSSPSFWALRRRKMLSSSLRRAAWAPMGPIAGISRATSQ
                     SITTSANGLIGSSQQHVRQRRYSSSSSKPSDGSNKVDSSSQTPAKGVNSAEKREGKASR
                     RRGKDSNGRNGSKQPTAFSRLPSVPSTQHLQPHDVHVASFFSIHRPISVSTTVPPTSTP
                     EAFDAIFTAKKPAKPEVDDVIFTLSSAVNSMENSAAHSGEQEGSLQYFDMEGNQLDGMN
                     LSDLKVSVEELTKPKDMAFSEFEDVPRETSSYSTVLTIHESIHSDGRKTYEAHTGPFVP
                     SGEMEAPGAIGESEAIIDVPHNSGTTYMERIRNNRTMHAISTKRRRRLKMKKHKLKKLR
                     KRTRTLRRKLEKA"
     mRNA            complement(join(39580..39644,39706..39809,39873..40029,
                     40118..40247,40334..40389,40474..40546))
                     /gene="VMA3_2"
                     /locus_tag="CAN33_52660"
                     /product="H(+)-transporting V0 sector ATPase subunit c"
     gene            complement(39580..40546)
                     /gene="VMA3_2"
                     /locus_tag="CAN33_52660"
     CDS             complement(join(39580..39644,39706..39809,39873..40029,
                     40118..40247,40334..40389,40474..40546))
                     /codon_start=1
                     /db_xref="InterPro:IPR000245"
                     /db_xref="InterPro:IPR002379"
                     /db_xref="InterPro:IPR011555"
                     /db_xref="InterPro:IPR035921"
                     /db_xref="PFAM:PF00137"
                     /gene="VMA3_2"
                     /locus_tag="CAN33_52660"
                     /note="GO_component: GO:0033179 - proton-transporting
                     V-type ATPase, V0 domain [Evidence IEA]; GO_component:
                     GO:0033177 - proton-transporting two-sector ATPase complex,
                     proton-transporting domain [Evidence IEA]; GO_function:
                     GO:0015078 - proton transmembrane transporter activity
                     [Evidence IEA]; GO_process: GO:1902600 - proton
                     transmembrane transport [Evidence IEA]"
                     /product="H(+)-transporting V0 sector ATPase subunit c"
                     /protein_id="ncbi_CAN33_52660-T1"
                     /transl_table=1
                     /translation="MATELWYVITSPTPFPSIPTIVPSFTCDPTLTDDTIELQATLKPF
                     FGALGCTSAIVFTCFGAAYGTAKAGVGVCGMAVLRPDLIVKNIVPIVMAGIIGIYGLVV
                     SVLIANDLGQKVPLYTGFIQLGAGLAVGLAGMAAGFAIGIVGDAGVRGTAQQPRLYVGM
                     ILILIFAEVLGLYGLIVALLMNSRSRIDATC"
     mRNA            join(44087..44103,44272..44406,44467..44488)
                     /gene="PMP3_2"
                     /locus_tag="CAN33_52665"
                     /product="plasma membrane proteolipid Pmp3"
     gene            44087..44488
                     /gene="PMP3_2"
                     /locus_tag="CAN33_52665"
     CDS             join(44087..44103,44272..44406,44467..44488)
                     /codon_start=1
                     /db_xref="InterPro:IPR000612"
                     /db_xref="PFAM:PF01679"
                     /gene="PMP3_2"
                     /locus_tag="CAN33_52665"
                     /note="EggNog:ENOG41; GO_component: GO:0016021 - integral
                     component of membrane [Evidence IEA]"
                     /product="plasma membrane proteolipid Pmp3"
                     /protein_id="ncbi_CAN33_52665-T1"
                     /transl_table=1
                     /translation="MPFTASDICKIIFAIILPPLGVFLERGCGADFLINICLTILGWLP
                     GVIHAFYIIFKY"
     mRNA            join(46108..46305,46390..46437)
                     /locus_tag="CAN33_52670"
                     /product="hypothetical protein"
     gene            46108..46437
                     /locus_tag="CAN33_52670"
     CDS             join(46108..46305,46390..46437)
                     /codon_start=1
                     /locus_tag="CAN33_52670"
                     /product="hypothetical protein"
                     /protein_id="ncbi_CAN33_52670-T1"
                     /transl_table=1
                     /translation="MFYENSLQRRLVRHLRLGTWSFATDSCYDHRDSDANRIKSHAKDC
                     NDDDDSDGAIYLQLQFGLQHWSFDGFNFAAFSHGNG"
ORIGIN
        1 ctacaaccta gccctccccc cctctctccc ctccagcatc cccaaaacct cccccacagc
       61 agcctgtccc ctctcaatcg caccatccac aaaccccctc cacccgtccg cccaatccgc
      121 gctcgcaaac acaacccgtc catgcggttt ctgaagttcc tccaagtatt ctgacgcagt
      181 atttggtccc cagcacgccc aagccccttt cgcatacgga tcattcatcc aatcatgggt
      241 ggcataggca tcaatatcca catccgggtt aacatcatgc ttgaatctct gcaagatata
      301 tttgctatcc ttcttattag taagttgatc gttgtaccca aatccaatgc accaggtgcc
      361 agacgggcct gttagctggg ttccattgtg atctgagaac gcaaagacaa agctggagtc
      421 actgccgtca tgtgcagtaa agaaccaacc cggtagtgtt tcgcgaagct tgaagtggat
      481 ctttgcgcct ttgttaatgt ggccttttgt gatggctgct tgtcggaggg gggtgagtgg
      541 gggttgaaat tggatgtcgt tgaggcagtt tctgtcgtta ggttagtcag gtggatatat
      601 ctaaagcaac agaaggtgag ataggaaaga aacatacagc ggaaccgtcg acaccaccgc
      661 acgagcccca accctcctcc catccttagt gacaacctcc accatatcac gaccatgatc
      721 aatctgctca acaaccgttc caaagctaac atgaccagtg aactccccca aaatagccct
      781 cgcaaaagaa gtcatccctc cactccccaa tttgtacacc cccgccaact caaacacccc
      841 agccatacta tgccctccca gcgcaaacca ccgcagcgcc tccacaaatc caatatcctt
      901 caccggcgca ctcccaaacg tactaacatt agacgcaaac agcactttct cccacctcga
      961 caacccatcc aaatccgaca tctccaaccg ctcctccaca ctaagataat catacctctt
     1021 ccacggcgcc ggccccctca gcgaatcatg cggatacggc atcaacgcac gactgtccag
     1081 cccatcaatt gcgaaaactt ctctgcaacg cgctcaagcg tagcctggta atctccaaca
     1141 gaaaccttct ccacaggacc actactggac ttgaaccact gatccacagg cgtgaatgac
     1201 cccgcagagg tcttcagatt ccggtgcagt ccgtaccgat gcagctcggc atacagatgc
     1261 ggctggttcc agtgaaccca ggtcccgccc atttcgatct cctcgccgag gaccttggct
     1321 gtccatgttc gaccgccgat gcggtcccgc gcttctagga gcaggacgtt gagattgtgc
     1381 ttcctgctta ggtcgcgggc tgcaattagt ccggcgaatc cggccccgat gactatcacg
     1441 tcgtagtggg tgcggagggc gggcgtgctg gggtggactg cgtctgtggg tagacctgag
     1501 gtggcttgct tgggagtcca gaggtagcct tcgctggagc gggacatgat taacgtacta
     1561 gggaatcgag tgatggtagt agttggggaa tgtggaggat cgcatgcgac ataaatatat
     1621 ctaaggtatg tgagagagga tgttgtgctg ttcaagtact actagttaat gaggacgggt
     1681 taccgagaga atccaggtga gtgttaagag tcctatccgt tacttccgag attggaatat
     1741 ccacgaccga tgctaaagtg tagctgatag tctcgacaat cgacgggcgg taggaaatag
     1801 tagagctgac gcactatttt gccaatttgg gtaatggtgc cgcccagcag gaatgggagt
     1861 atggatgagg agcatagatc agcgggtgtg ttggttctgg gcattgattg atcctttcat
     1921 tgagaatctc tcgtccatgc gcacgtagta acttttaggg catatccact attcgcaatg
     1981 ccaactgatt ctagttagtt caaacccctc cagtaaaaac atgagcgcaa ctggacgtta
     2041 tctattttct actatgcatg ttacagcaac aacaatttcc ttataaactc tgcacgattg
     2101 gcttgctaga cactatcaca taagatacaa ccgactcaac accgaatcct acaccataaa
     2161 ccaatgacat aaatcaaagc ctcgccattt cacgaccccc acacttccac gctacgccat
     2221 aactatctgt agaaaaagtg atagtacttc cccttggaaa gaagaacgta tcacctagcc
     2281 tcactgtagc ggtctgtcca ctctcgtcac gaagattgat ttccccttcg taaagataaa
     2341 agcgtaatca gccaaaacat atcttatcac cagcatccat ataaattggt ccacttaccc
     2401 tcaatgacca ccccaacctc atcatacgag tacgtcggag gcgtagcttc aggtcctttc
     2461 tcaattcgga accaagatcc gacgatagga ttcttctcct cgcttctgct tgttcctagc
     2521 aggtcctctg cgcctctgct gtcaatatct gtcaatgaga agggtggggg aaagaggagg
     2581 taccaaagaa gacgttaggt atgtctccgt atctggggac attgtacatt gcagctttgc
     2641 ttttcacttg gaggaccatt tcgatggtgg tttggttggg agatgggatt ggagactaat
     2701 tgagaaagtg ttgagtacta tggtaggctt ggagtgaagg ctattatata tgtaattatt
     2761 catcagtcaa ggaatgtatg gcttcgggtg gaattgctgt aacagattcc attgcatgag
     2821 agttattcag aagactaagt gccgaaggcg ggaataagag catgggtgca ctattacaag
     2881 ccatttcatc atactaacac tccgatgagg gattcatggc attccttact aggcaagttc
     2941 acgaccccca actggaagaa catctagaag tatgaaatct gaccaatcgc attccttgtt
     3001 ccagttgacg cactattttc cccaataagg tttagtgcca tacatgatct aaccaaagat
     3061 tgactccaaa ttctcggagc tcatgacctc ggtccactgg atgtactccc attcctggtc
     3121 aggatcctca gcggccctcc gcatgtcggc tagaaaccac accttatcga ggatcttctg
     3181 cgcgcggcca atggtaacga gtcctacaat ctcctgaacg gtctttaccc tctcccgcac
     3241 gaagttcctc cagaagagat aggtatcttg ctgcaacatg gaagtgggga cgtccgacga
     3301 gaaacaagga agttgcaaag cgctacccgc gataatcaat ggaatcgtga gcaaacagta
     3361 aaccccagac gtgtggggaa gcacgccaat ggtggttagc acattggtgg ccaggcccaa
     3421 gatgctgtgg gttaggctaa aatccacaga gtgggctcca tgcagttcag ggaaggtcat
     3481 gtagagctga agtaatccta caagccggta gatgcttgca attcgctgga ggtggtcgac
     3541 aggcgtccgg gaatcagctg tgtcttctat ctggtggatt gatagggttc tgtaggattg
     3601 gagcgcatct tcaatggctt tagcccgttc aagcatgtcg gggcctacat ggccccaaaa
     3661 gcctacaggc aattgtctgg ctagcgatcg ctgccttgtc aatataccaa tctgggccaa
     3721 atgtataaaa agtggcgtgc agatccctgt ccatggattg acgtatacat ggcatgtctc
     3781 gaaggagaat ggcatgaggt aggatatcga gtctagggac tggttgtgta caaacgaggc
     3841 gactgcttcc cagtaggaca taatgcccgt aatcatagtt ctggtccgag ggcagcatgc
     3901 cgggacggta gtaatccatt tccggaacaa cgtgcgtgca ccacggagat gtgtgacccc
     3961 gagttgagtg ggatcatgcc acccctacga aaggccatca gcttaacatc aaaaggctgg
     4021 catggacgca ctgagaatgg gtacctctgt catgcccaag agtatgctac caattaagat
     4081 ctcggcaacg ttatcgagtg gtgatccatt gtttatttct tgtgtcaaaa ccccctgtgt
     4141 gattctagct ttcaagcagg atagtgcttc tgtccggtgc cgcagcgtga tcgtcaacat
     4201 atctctttgt cttgccgtca gatgggcggc ggacatggac agtacgcagt agtgaatcag
     4261 aggacgggag cttatcaggg atcccacttc ggcacggaag aagttcttgt gggagtcaaa
     4321 gcacgaattg actcggcaaa cattggaaaa gtaatgcctg agaagagctg cgtcatcgtc
     4381 tttttgggta gacaaagtcg gttccgctaa tatggttcct gtccataatt caccacaatc
     4441 attacctacc atagtcgaag ggatccagat atctttcggt ggcgaactgt ttgccgcaga
     4501 gattgaggcc tggtctgatc caacagcagt ctcattctgc gcgggctgga catctgtctg
     4561 cacaggcagg gagcgtgtgg cgtcgtccgg cactgtggac tggaacaaga tgggtcgtaa
     4621 tggctggacg ggctctattc tttggagcac ctgctcggag gagctcagga ctgcgctatt
     4681 attcccactt ctccccacct catacttgga cgaccacttc aatgggcgtt tgtatcccgg
     4741 gcattcgaag cgtttgcggg tacattgatt acacacagga agcgtctcgt cgcatttgat
     4801 tcgctgtcaa ctaacttagc ctggatatta ggaggtagac acaattgggt ttgttacacc
     4861 caccctttgt ttgcatctta gacagccatc tggcatcaga ggcgtgtcag tttccgcaat
     4921 gtcattatcc catggctcag atactcactg cgagtcttga acctgcggcg agaggttggc
     4981 tgtggatctg acattgataa cgagtggaga gactaaagtg cagttttgct cgtgaagaca
     5041 atgatgtgaa gtggatgaag cttattgtac ctggcggcaa tgctccgcag gagttgataa
     5101 cgtatccaag ttcttccccg caattccgca gtcacgataa gcaccggaac gttccactgg
     5161 cccgcacttt ttatactatt tcagatacga aaagttaata gtctcgcagc agtatatcag
     5221 ctacaaaaag aacgaatagc gatagctgtt ccgaagatgc ttatcttcct ggatgcgacc
     5281 ggtcattgga cattcatgat ggactctata cctctcagtt tccgctttat acatgcgatt
     5341 cctaccaaaa tacgcttcaa ttttgttgag cccacggcat ccctattgct aaagacataa
     5401 tgtcgccgag tatgaaggcc cccgcagata ctatgactgc caagtcggca gacgagggcg
     5461 agaacgagct cagaattgga gaggctatcc caatcaaggt cagtattctt tttgagtagt
     5521 ccacaagcct ggcattgaaa tggacaacct ctgatgacga tgcttgatct atagaagccc
     5581 ttttctcgac ttacaatctt ttccctcact gtggttctca tgtcaacttg ggaggcgctt
     5641 tccaggtaca gtcccacgtt cactatccaa caccataatc tagtgtctga tcacaccatc
     5701 catgatagta caatgtcctc aggtctcgtt agcggtggcc ctgtatctct catctatgga
     5761 tttatacgtg tgttctgcct cttcgactat tcacaactag tctgaccccg atcaaagtgg
     5821 caatcgtggg ctccatggca acagcggcct ccttggggga gatggtgtcc atgtcagtac
     5881 cttgtgtttt cgcacttact accgttacct gaccttgctg agtggtaggt acccgacagc
     5941 tggaggtcag tatcacttta tcgcgaagtt cgcacccgac aaatggcaga atattctgag
     6001 ctggtttgta gggtggatag gtaggatgta ctatgataag gcttatattc caccgtgctc
     6061 atctttttct acattcatag gaacctttgg gtgggtatcg ttcactgcaa gcgctccata
     6121 tcttgctgca ggcatgatac aaggccttgt agttctcaca tgcgaggcgt atcagcctca
     6181 gcgctggcat ctatcattaa tatactgggc tcttgttggt ttcgccacag ctctcaacat
     6241 ctggggcagt cgtttgttct cactcgtaga gacggcgtct ctcgtcattc acctggtcgg
     6301 atttgtcgtt gtcctgatag ttatgtgggt ttgcgtccca gcaaaacaca acgccacatt
     6361 tgtctttact accttcctga atagcaccgg atggtcgagt aatggccttg cctggtgcct
     6421 aggaatgctc tccagctgct atgtactggc aggttcgtga gaatccaccc tggcatcgaa
     6481 aatctacatc ctgacccact gagcttaggc tacgacggag ccattcatct ttgcgaagag
     6541 atggttaatc cagaaaccgc cgtcccatac tgtatgctgg gctcgcttac catcaacgac
     6601 atattaggtt tcgtttttct actcaccatt ctgttctgca tgggagacat ggaaaacgca
     6661 cttgataccc cgaccaacta tccaataatc gaaatttttc gcagtgtaac gggatcatcg
     6721 gctggaagct gtgccctgac ggctgttttg ataatcgcag cctggctggg caccattgcg
     6781 ctgctggcat caaccgctcg tatggttctg tccttagctc gggatagagg tacgagcggc
     6841 cacctcatcc ctcccatttc tctttcactg acccacctag ctctcccatt ttccggttat
     6901 ctctctcagc ttgatactca cacagactta ccgaagcgcg caatcatcac aacgagcagt
     6961 ctgctcgtgc tgttcgggct gatcaacatc gcttccacta ctgctttcaa cgccatcctc
     7021 tcacttgccg tcttaggatt acacatctca taccttgtcc ctatcctatt tttcctatgg
     7081 cgccgccttt ccgccccaca cagtttaagc tatgggccat ggaggcttgg ccgcgctggc
     7141 gttgccatca atgttatcgc catcatctat ctgctattca ccagcatctt catggtgttt
     7201 ccctcctatc aacccgtcac tccatctaac atgaactacg cttctttgat ctttgggttt
     7261 gtttggctga tgagcgtggt tttctggatt gtgcggggtc gaaaggaata tgatggtcct
     7321 gctgttttgt gaggggacta ttttccatac aaataggaat ataaatggaa ggggcagttt
     7381 taaaggggac ataccatagc acatcaagac actagcagcc tcaacaacaa tggatagaaa
     7441 ggctatatgt ggggtcgttt acaggttcat aatcactgtt ttccctataa aaataaactt
     7501 acaccatgtt gagcaggtaa tgtattcacc aaaagcccta ttccggcatt cacatgttct
     7561 tatatacttc cgcccaaatc catgtattgg ctatgtattt cctccctcca ctgtctcctg
     7621 tcaatcccaa tgcgtatgat ggtactcttc gtcgagaatg ccagcttggc attatcgggt
     7681 aaggcagtca tatgagggga tctattacag taagaatgaa tatatattta ctttgccaag
     7741 atatgaaagc gttagcacga gcatcgattg atgaacgaac atcaagctct aggtgggaga
     7801 ctgaaatgac cggcttgact atgggagctg ggtgatggta atcttctaca tcttcatgtt
     7861 ctgcggtctt gtatgccctg ccatggaggt ctctgttaca ctatctcttt ttcctctctc
     7921 tcttttaatc taccagtgtc gtacatagag gtacttggaa ctgatggaca attgcgtagt
     7981 ctctatcatt cttaatccgt ggaatatccg tggagctatg tgaaacctat tgactcaaga
     8041 ggtctggttt cattgctttg atagtggaac ccaaagtaga tctaaacagc tcagcactat
     8101 catagacgat tcacttggac actgtaacgt cctccacctc gggcgacggc tctttctttt
     8161 ccggcccgta ttctgtctcc agcgtggttc gcaactccac ctccttctcc agccacgcaa
     8221 ataagaagcc tagtccagca aacaccacag aaatctgcca cactcgctgg agcgctgcgg
     8281 tatacgcgtc gataatcatc gattgaacct cgggcgaaaa ttgcatgaca aattcccgcg
     8341 aggcttgctg gtacgcgtta cccgtgtttt gtagcacctg cgccgcgtgt cccgtatcgt
     8401 tctgcgcgct cacctgcgcg gcgaatcgat tattgaagat agcggccggg atggagacgc
     8461 cccagacggc gccaaatgcg cggcaaaatg cccaggttgc tgtcgaggtg gccacgtcag
     8521 cctcggacag cgcggcctgg gcagctggca gggttgaggt gacgatgaag cctgagccaa
     8581 tggccgctag cagctggtag ccgacccagg ctcctgtgct ggagttctgg tcgagaaggc
     8641 tgaagaggcc catgccgagg gccatgaagg cgaagccact gatttgtatg ggcttgtacc
     8701 ggccggtctt agtaacaaga gcaccggcaa cgatggcggc agggacagtg acgattacag
     8761 tgggcaacaa ttccactccg gatcgagtcg acgtgcttag ctgaactcct tggaagtata
     8821 ccggcaggaa gtatagctcc cagtacatca gcatcccatg cagaaagctg ataacgaacg
     8881 cggcaaaggt ggtgcggttc gcgaagagac gagggggcat ggttggctct ggacagagct
     8941 tgggcgtcac ctgcaccagg gcgaaggcga tcagtccaat gagtcccagc actaacggca
     9001 caatgacacg ccagcttgac caggggtatg aggtgccacc gaaactgagc gcgatgagaa
     9061 ctgctaccac cgcggcgacc agtatagtat tacctagcca gtcaatgcgt ttcatcttgt
     9121 ccgcgaaggt ggtgtgcttc tgagatttga cctggaggaa gaggatcatg aacaccatcg
     9181 cgctgccggc gattggaaga ctgatataga atgcccaccg ccaggtgacg tgctgtgtaa
     9241 aggcaccccc gatgaagggc ccgatggacg atcccacggc gaacacgacg aagatgaggg
     9301 cggtcacttg gcctcgctcg cgtaagggga cgagatcaca gacgaccacg tcgatgagca
     9361 tgttgacacc tccgaggccc actccctgga ttgtgcgccc ggcaataagc atcgcggtcg
     9421 aactggcacc accgctgatg ccactgccta gagcaaagaa agccactgcg gagatcaggg
     9481 gccatcgtcg accgaagacg tcggccaatt gtccaaagag cggctggacg gcggtactga
     9541 aagggccatg gcggacgatt tagcgttaca ggaagaaaga agacgtgcgg aggagagaga
     9601 gtcaatacct tgatagaaag agtgcgttga caaaccaaac atacgactct cctgcgttca
     9661 aatcgcgcga gatcgtgggc agagcagtcg atggaaccgt acattcgatc gcagtgagga
     9721 gggatgttat tgacagtcca gcaataatca gccagaatcg ccaaccacga gcagccatgt
     9781 tttgcttcta tcagagaggg ctaatcagca ggatactttg ctccgatcga aggttgcaga
     9841 gcgttacttg tggtttaccc tttcttccta ttcttctttt tttttgctcc ggggagatgt
     9901 cgagcgggag cgagaggcgc cattggggac cggcgatggc tactgcaagc tgtcagcact
     9961 aagtgagtag tggatataac taaggcgttc aaggcggcag gagcaattag ttagcgaggc
    10021 ttagttgcat cggctaaggc tgaacccctg caaagcttcc cctgtgccac caagtgagca
    10081 gtgtgagttg gtgactttcg ggggttgcat cttacatgcg cctctagccc agccatcatg
    10141 ttcagaattc acgaagggga taaccccaat ctctttccta acggggaaag gatcttcctc
    10201 acagccttgt atctacatag taattcagag agaaggatga gggggttcat gacatggtag
    10261 tctttggttc ttacaaggta ctactaagcc ttttgattat tccgtccacc caaagtaagc
    10321 actagggcat agagactcca catcccctca tctcctttcc gtccgcaccc aacccacctt
    10381 ttgctcctcc ctctcacgga ccatgatgga tctccacctt ccggaccacc tcaatctttc
    10441 gtaattcgtg tgatggcggt gtttcccaac tcgtgcctcg ggtcgcagag tcctccacat
    10501 catcctcggg gcttctctga aggtccagca tgctttccgt ccccatgtcc ttccgctttc
    10561 tactgttgga tgcgtagtta atcgatagca tgtatcctcc ctgcttgttc catgggcggg
    10621 ggttgggagt ttggcggagt cgcaacaagg gagccgaggc ggggatgcat gcggtcacga
    10681 taccgaagca gagctgcact gtggtccaaa tgcaggtgtc tgtatctgcc catgtcatat
    10741 cgcccccaag taccatggtc caggcatagt agaagcgcac ggctgaaatc gccgtaacaa
    10801 acaatccaag tgagaaggtg aagatgatga tgattttccg gcggagggcc atctggaggt
    10861 tccacaagac caccgccgga ataccgagca gaattagttc ggaaaacgaa tcaagcagaa
    10921 gcggaataca cagatgggtc ctttgaggca tgcacgtata atcttccagg ggctgaggcg
    10981 cctcgtagcc gaagatgggg tagacacgaa gccagaacat ctgtggtggc aagcaggcac
    11041 agacgaagac gatcgtcgag gcgactccca agccaagaca gaaggcaaag agcccccaga
    11101 tggtccagcg aacccctcga acaatggtcg agaaggcccg ttggtaaaac actaagactg
    11161 acaacttggt gaacatgagt gcgggggctt ggattatcgt tatgatgtac gacatctcca
    11221 ctacaaatgc cattcgctct ggaggatgcg ggtcttcgct gatgacccag tactatccaa
    11281 aatcagattc ccatcaaacg gcatgattcc cccgccagaa aactaggcgg gagagaagag
    11341 gagatgctgg ggcctcttac tgcatgctga cccatgccgc tagccactgc ggcaatcaca
    11401 cagcccgcgg tcgccagggt gaaaatggcc gcgagaatga tgagaataca atctgccgtc
    11461 cagatcctgt gaatgagcga ttgtgcccac acacggatgc tcaaccctat gacacagaag
    11521 atcatgctag taatacatgc tcccagcatc tcgggtccgc gatttgatgt ggagtggtcg
    11581 ctgagcaagg catctacctc gccagcagtg ctggaagtag ccatattggt tcaaccgata
    11641 gaggggaggg agggtgacac tgagtctgac gatagtctcg aatcatgtca gagcaattgc
    11701 gagccggctt tcagaaacga gttaaataaa tattaccacc tcagggacga gacggaagca
    11761 aagcgtttca ggcagacttg ggggccaaat ctagatgcag gccttatgcg atcagattca
    11821 aggatggcta ggagttgagt cggcttccaa ggcttccaag gctctcttag ccaggctgag
    11881 gatgttcaaa tggtcagcct agcggaaagt acagagacgc aacccgctat taccgatggg
    11941 gataaagcat atacaacctc aagcggagag ccttagcttg aggtcagtgt ataaatatcc
    12001 gcaatatgac ggtccagaag gggggcggag aatgggcttc atcatcacat aactccaaga
    12061 ttgattggtt catcttcccc aatgattctt ccggattcgc agtatgcgtt ggtcgtgcag
    12121 gggcccggtt cattgcaatt gctcagccac gcccctgttc cctcgcttgg agcagatcag
    12181 gtcctgatcg aggtgaaggg ggtggcacta aacccctcag actggaagat gcttgatact
    12241 gcagcagcaa acccgggcac catcagtgga ggggactttg ctggggttgt cgttgcgtgt
    12301 gggagggagg tgaccgaggc ggcgattggg gatcgtctgt gtggattcgt ttttggagca
    12361 gcttcatccg gcgcatttgc ccagttcgtc atggtccatc ccagtctctg ttttcgaatc
    12421 ccaccctcca tgtcgtttga ggccgccgcc tcccttggac tagggctaat gacgggggga
    12481 ttgatgctgc agtctctcca cctcaatccg ctacgagctg cagagtccac gcctgatcat
    12541 tgggtgttgg tctatggcgg ctcaacggca acaggaaccc tcgccatcca gctcctacgc
    12601 tatcatggct atcgcgtcat caccacttgt tctcctcgga attttgaact agtgcgacgg
    12661 gtgggggcag tagctacgtt tgactatacc tcccccacct gcaaggagga cattcgggct
    12721 tacaccggtg gcactctcat gcatgtgatg gattgtattg cggattcacg cgctactaca
    12781 atttgttacg gggccatcgg cgaagcaggc gggcggtact gtgccttgaa tcaatttccc
    12841 gcgcaattgc accgccgtcg tgcctctgtc tctccggagt ggatccatag tgcgaccatc
    12901 ttcggaggcg atgttcagct ggcaggctcc tactaccgga cagcacgacc ggaggatcgt
    12961 gaatttgcca tagaatgggc gcgatattgt accgagcttc tagcccaggg aaaactacaa
    13021 ccgcatccac ttcaggtgca gcagggaggt cttgcgcgtg tggtcgagga cttggtcctt
    13081 ctacgcaatc agcaaatcac gggcaagaag ctggtatatc cactgtacta attgggattt
    13141 gtactgaatt cttttctgtt tttttgttat agattagtca acttcgtttt accaaacaat
    13201 aatgacattc acttgatgct attcactaac agctagatct aagcagccgg acgagagccc
    13261 accctgtaga gtagctcgtt tcagatacga acatcctcgg gagcatcagt cttcttgcta
    13321 ccctgaccca tggccgtaaa agcctcccag ctctcgcggt caatgtccac aattttgccc
    13381 tcatccacaa agacctcctc ccagcccgcg gtgactgtgg cccgctcctg atccagaata
    13441 tggtcctctc ctgcgacaag gctctggaat tccggatctg tgacgattgc ctgcagagtt
    13501 tcggggtcag gcacgtacat cgacaccgaa acgtcgtggt cgtcgacaat ccaaccggga
    13561 cggacagccc acgggatttt gtcggtgatc agactcttgg tgataggggg agtgtacacc
    13621 tagcaaggga aagagttttt agtcaattga agagggggag agatatgtaa gcaacaatcg
    13681 acagggcact tacgtgcgta atcttgtagg cgccatgtct ttcctggata cgggcagcct
    13741 taggtgcatg ctgtctggtt ccgtattcat ggaagtcctt ccaagagata ccctccttct
    13801 tgtagcgaaa ggaggtcagc ttaaggacca attgcttctg gggagccatg ttttgttcta
    13861 gtttgggaag aaggagaacg tgacaattgt aatttggaag agagaatgat gtgatgtgtt
    13921 tgaagaatga agggaagact gtcatatcaa cccgggaaaa gacctgaatt tatatccgtc
    13981 attcctactt cgtagagtgg catgacatcc agtagctgat actatcgagt ggtaaaacga
    14041 atccggctca tgaaggcaat aatcagcgta gtatccagac aaagaatggc ccgtgccggg
    14101 atcttccttt caggctgagg cgtttttcct ccgtcagcct gttcaccacc gagtaaatag
    14161 taggatccaa ctaatacaca ctaactttct agtttgctta cgctggaccg ccggccccac
    14221 ttcacttgcg tcgcccctca gacccactgc tagattaaac atcccccagt tagcatacca
    14281 acacttttag attatcacca cggaagagtc ctacaatcac atttgtacca tgcagcgcag
    14341 acacttcgcc ttcccagttg gtcttagacc gtgtctatgc aatttcaacc gcccccggtt
    14401 cagcctcgtc ggcagctttg gtgcggacgg ccgtggagat tacggcgtat cgtccggctc
    14461 gtccaatgcc cgccattaca attgacaatg atatcccgcg catacttctc ctctcgaggt
    14521 atctgatctt ctcgaaagaa gttgtggccg acacagactt acctttgatt acttgctagt
    14581 catctcgtct gacgttttcg gggaatatgg catacccaca agctgaaccg gtggccatta
    14641 tcgggagtgc ttgtcgcttt cctggcgcca atagtcccga ggagctttgg aatttacttc
    14701 tcagacctcg cgatctcagc aagaagattc ctgaggaccg attcagtgct gcgggctttt
    14761 ggaatgcagt tggatcgcat catggtactt ctaatgtaac gcattcatat ttcttggagg
    14821 gtgattcgcg acggtttgat gcaaacttct tcaatatcaa tccccgggaa gcagcatcaa
    14881 tcgaccctca acaccgcttg ctattagaaa ccgtctatga agcgttggag tccgccggcc
    14941 tctcgttgga ggcaatgtgc ggtaccaata ccggggtcta tgcaggcctg atgtgcgccg
    15001 actatctgga tttacagctg cgggatccag atactatagc acaataccat gcaacgggta
    15061 cagcccgcag catcttaagc aatcgggtat cttacttttt cgactggaag ggcccttcaa
    15121 tgactatcga cacggcctgc tcctcgagtc tggtggctgt acacttggct gtgcaggcac
    15181 ttcggcatag cgagtgctca acagctattg ctgccggagc aaacttgatt ttgggaccgg
    15241 agatgtatat cgcggagtca aatctacaca tgctatcccc aacaggcaca tccaaaatgt
    15301 gggatgccga tgctaatggc tatgcacggg gcgaagggat tggagtggta gtcctgaagc
    15361 ggttgggaga tgccttgcgt gcaggagatc cgattgaatg cgtgattcga gagactgcgg
    15421 tcaactccga tggacggaca aatggaatta caatgccctt ggccacaagc caatcgtcat
    15481 tgatccaaga aacctaccgc aaagcaggac tgaatccact cagtgagctt gaccggcatg
    15541 taccctcatt ccccagacca tgcagcctca accttgctaa cctgtctctc agatgccaat
    15601 tctttgaggc tcacggcaca ggaaccccag tgggagatcc gctagaagcg gaggctatca
    15661 aatgcgcttt ctttcccgat caacatcctg catgcgcaga accaccaagg catctattga
    15721 atgtcggctc cgttaagact gtcattggcc acacggaggg cgccgccggg atagcgggtc
    15781 ttcttaaagc ctcgctggca cttcagaatg gggttgttcc tccgaatctg catttcaacc
    15841 gtctgaatcc taagattgct ccgttttatg caaacttgca tgttccgacg gtgcctctgt
    15901 cgtggcctaa agttgaggtg gcccgcgcct cagtcaatag ctttggattt ggtggaacca
    15961 atgcacattg tgtatgtact tctactaaat cacgcagatt atttctcatt tttttattta
    16021 tttgtttatt tatttttatt tttatttttt tttactgatt taccgctcca gattcttgaa
    16081 cgttatacac catcagttca tggagtgcaa cagctccttc ccatgtgcgg aagttccctg
    16141 gcgacgaccg cgcaacatga atcaccactt atctttccat tatcggcgtg ttcacagcga
    16201 tctttgactc gcctggtgca aagatacgca gcatatattg ccgccaaccc atcagtggat
    16261 ttacaaaatg tggcatttac agtacggagt cgctctgctc tctctgccaa gcactgcttt
    16321 gttgcactat ctaggggctc gttaatcgag cagttaagct catacacggc acccagccac
    16381 agcattggac agggggcaca tgctcaactc gcaagagtta ctgctggtgt ccctcgtgtg
    16441 cttggtatct ttaccggcca gggcgcgcag tggccaacta tgggtcgcaa tctcattctt
    16501 cggtcgccag tctttgctgc cactattgaa cgtctggata tcgtgcttgg acgggttcca
    16561 aacccgccag actggtgtct ccgcgacgaa ttgcttgcag atgcgggttc atcgcgttgc
    16621 tctgattctg aattctctca gcctctttgt acggcagttc agattgcctt ggttgactta
    16681 cttcacagtg tgggggttcg gttcaacgtg gttgtgggac atagcagtgg ggaaattgct
    16741 gccgtaagta tacgcaaatc caagctgctt tcaatcatca attttctcac aacctgtata
    16801 caggcctata ccgcgggatg tctctcagct gaagaggcga ttacagtggc ttactaccgc
    16861 gggtactact cgcaccgagc ctcttcaaca actggggcta agctctcaat gatggccgct
    16921 ggaatcgggt ttgcggaagc cctacgcatg tgtgaccgtg ctgagtataa aggaaagatt
    16981 ttccccgcag ccagcaatgc gccattctca accacaatca gtggtgacga aaagtcactt
    17041 catcaagctc tgtcggaatt ggccagtcag gagaggtttg cacgcatgct acgggtcgac
    17101 aaagcgtatc atacgcctta tatgcgtccc tgcgcactgc cctacttgaa ttccttgcat
    17161 caatccaacg ttcaaggtcg gattggagat ccttcatgca catggatatc ttcagtacat
    17221 ggctttgaga tggatatgag ctctgacccg gtgaacagtg actactgggt agaaaacctt
    17281 ctccagcctg tccttttctc tgaagccctg ggccaagcta ttcgagatca tggccccttc
    17341 tcacttgctc tagaggtcgg tccgcatcct gctatgaagg ggccgaccgg acagaacctc
    17401 aaggcctttg gtcacaatga gattccttat cacggctcac tcactagagg tgaagatgac
    17461 acactcgctc tcggccagtg tctggctagt gtgtgggcaa cattcggccc ctctgcggtc
    17521 aacctgtcca aactggcatc ttccttgggc ggcgaggctg cctctcgacc actcaggatc
    17581 atgaaggctc tgcccacata cccgtgggat cacgagacaa tacactggag ggagtctcgc
    17641 cggtcaaaac agtactgtag ccgtccggct ccccacgagc tgcttggtgc atgcaccgaa
    17701 cggtccgaag gccaaatctg ctggcgcaac atattccatg tccatgaaat ctcgtggctg
    17761 cgggatcaca aagtgcacgg ggaagttgtc ttccccgccg cgggttactg tgtgatggcc
    17821 attgaagcgg caatggcatt tttggcccaa ccgattcgtc tcattgagct acagcagctt
    17881 gttatccacc ggggagtccg tatcgaagat aattctattg gcaccgagat gatttccact
    17941 ctgtcactgg cccctacagg gaacggtagc aggtcctctc cagacctgtc cactgccgcc
    18001 tttaatttct ctctcaccgc gggaaaggca gatggtacgg agcaatccag cattcgattt
    18061 gaaactaaga tctcggtcac attgggcaat ccccatatcg ccacgctccc tgcgtcccag
    18121 cgaaactcag cagagtggcc cgctgccgat gttgacaggt tctatctgtc catgcaggag
    18181 attggtttgg agtatactgg cgtcttccgc tcaatgacga gctgtgaacg caggtggaag
    18241 aaagcttccg ctcgtatagc accgatcccc agctccatga tcatacaccc gggattcctg
    18301 gataccactt tccaaacgct cttcctagga atggcagcgc caggggatga gtaagtatta
    18361 ttacttgttg gagtcaacat gagagtcatt gacattcgtt taggagcctt cggactacat
    18421 atctgccgac gaagatacag tctatccgag tcaatcccgc aatattggaa gatggtagtc
    18481 ctgttgcgat gccatatcat attgacacaa ctattacaga ccttcattgc ccgactcagg
    18541 aaagtcaggc atcgttcact ggagacgttg acgtgtacag tgatgggaac tgcgtaattc
    18601 agatcgaagg gctcgcatgc gtggcccttg ggtcgctgac aaaggctgac gaccgcaaca
    18661 tgttccacac gaccacctgg gagctagata ttctatgcgg aatgtcggca tcccgggtgt
    18721 ctcctgagtc agagtatctt gcgttactgg aggagtacga gagcatagcc cgtcagtacg
    18781 ttgaaggacg ttgcgtctcc agttccacgt tgtcgagccc gacgtcgcct ggtgaacaat
    18841 tgatagatgc actgcatgcg ggaagaaaca accatcatac caatgggatc gaaaaccggt
    18901 ctcactcacg agactattgg cagtcaggcg ttggtcctca acgcatccgc aaatatctag
    18961 cgcagactgc caagcagatc gcccataaac accctcagat gacaatcatg caactgattc
    19021 atgtcagtga tgatgaggga tccgctgttc ggatgatact cgattcattg gaagattctt
    19081 tcgcgtcgta tgtggttaca ggcctgtccg aagatgtgtt gaggcatgcg caggcctgcg
    19141 tagccacccc cgatgagcgg gtgcgattcg acgtcttcga tacattccag cgcagtgtca
    19201 atggagacag tgagcagggc tttgacctcg tgattgcgaa ccttggtcag tcacctgaat
    19261 cagacaaggc tcaccaggtg ctgaatagtg tccgacaatt attgagaccg ggtggatatg
    19321 tcctccttca agctgttact ggaaggggtc tttttcccgg cctgatcctt gataaccttg
    19381 tggggcatag ctcggggccg atggctagga gtgaggcaac gtgggagagg acgctgagaa
    19441 atctcggata ttctggcatt caatcaatgg tatatgattc aggaatggcc caccctcact
    19501 gccattccct aatcctgtcg caagccatga cgccctcctt gagccagatc ctacgaccat
    19561 caatcgcact cgacccgctt tcttcggaag aaaagatact aataattggt ggcgagacag
    19621 cactcggttc gcgtgtagta cgcgagcttc aacctcttct taggccatgg aagaactcta
    19681 tactcattct tccttcttta actgatattg cttccttcga ctcgcatgtt gcgaaacatg
    19741 tcctatgtct ggccgacttt gaagctccca tctttcgaga cttcagcccc ttacacttcg
    19801 atgcccttca gaagcttttt caacagcccc ggaacgtatt tttggtgaca aggggtttca
    19861 aacaaggtga tccctatagc tccatgactg ttggacttgc ccgcgttctc cgtactgagc
    19921 tgccttcatc gaatgtggtc cttctggatg tggatcgaga cgacaatctg gataccgccc
    19981 agcttgccac actgtttggc caattcataa gcggaattca gctacagtca gacgacacgc
    20041 ggacccttct aaagcaagag ttagagatgg cactggaaaa cggcgatctt tacatccctc
    20101 gaatcaagca tgcaaaagat atgaatgacc gattcaattc cgcgtttcga caaatcccgg
    20161 cgactcatca acctcagctc actgcgcagc tcaacgtccc attcgagaag ccagtaccta
    20221 ttcgagtcct ttgccgctcc tccagtgcct tgatggttga cgacgatgca tcttactttc
    20281 tctgcttggg gaaggcgcgg ttgggcaact tggagcagtg tgtactcgcg tttacaccct
    20341 ctgcggatga tctggtcttc cttgaggaac tgtctcttct ccaatgcaat attgataaag
    20401 atatggcccc caaagtacta cctgcagtaa tcggtttcta tatttccgcg cgcatacaaa
    20461 aatttgcctc aagtggcaga acagttatct tcaccaacga acccttgttg gcccgagctc
    20521 tcgtttcgac tgtggaggaa acagagcaca tatctataac actcgctact tcgaacctat
    20581 cgatcgcact gtggcacgaa tctatagctt actggcatcc atacactgcc acacggaaca
    20641 tcaagcatct tcttccacct gacatagatc tcttcatcaa cctagaaaag gagccaaact
    20701 cactgtgcga tcgtgtcctc aatgcactgt cgtcaaaatg taccatacgc ggaagagaac
    20761 atttcttctc tgcgcatgca aggcaacccc aaagtgggtt gagcagaagc tacaaagagt
    20821 acttgcaatt tctatggagt cagtacaacg gacacgcaaa ctctctacca cctgcgactg
    20881 aaatcgagtc actcggggcc accgaagttt gtgcaatcga gcagtatcga tcggagacgc
    20941 tagttcgacg cctagatgcc cgagcattct tccgcgatga tgccacatac ttcttggtcg
    21001 gcatgacagg tgaactgggt cactccttgg cgcgttggat ggtcgcgcac ggggtgcgct
    21061 acctcgcaat cgccagtcga tcccccaagc ctgcgagatg gtatcaagaa cttgaggagc
    21121 aggggtgcca agtattggtc ctgagcctcg atgtctgtga ccgtgaagat ttgcagcgcg
    21181 ttcatgcgca gattcatcga gcgatgccac caatcgccgg cattgtgaac ggagccatgg
    21241 tgctcgccga tggtgcgttc gtgaacatgt cctacgaaga ttttgttcgg gtcttggaac
    21301 caaaagtgaa ggggacagag aacctggatc agctatacaa tcagccaggc ttggacttct
    21361 tcatcctctt gtctagcact gccaccctga ttggcaattc gggacaaagt aactactcag
    21421 tagccaatat ggtatgtgtc tgacctctac caccgtgtct ttgctataaa acaaattctc
    21481 actctatcct agtatatgca aggggttgca aggcgacgac agcagcgggg actggcggga
    21541 tcgtgtgttg atattggcat ggtcctgggt ctcggtgtgg tgactcgtaa cgtgactcat
    21601 gagaagaccc tacgcaaggc tggtctgctc gcgatttcgg agacggactt ccactgcatc
    21661 ttcgcagaag ctatgcgcgt aggatgggaa ggtgtcacgg actcgccatg tttctcaact
    21721 ggcctgcatg ttcccccggg gcaatcgagg ccgcagtggt acgatgaccc gcgatttgcg
    21781 cactttcatg taatggaaga tctggattcg aagtcgcagc accgaacaag aactcaactc
    21841 ctccaagatc gcctcagaaa ccctgtcgaa atggccgttg ccgaatcttg gattcaggaa
    21901 gcgttcatta caatgctgca aaaactcctg cagttgccgg gtccaatcac caatatcacg
    21961 caacccttga cccagttggg aattgattcc ttactcagca cagagatcaa agggtggttt
    22021 tataaggagc tgaactttca cgtttcggtt ctgaagcttc taggaggtac ttctatcatc
    22081 gaaagtaagc ctctccccat tccggacccg tatgaatgag tcctgacgtg ttcccttagt
    22141 atgtcgagaa gcaacggaat gttttttcca ggccgagtcc ttatacatga acgtgagcta
    22201 tgagccaaag gctgtagtaa ccaccccaac gcgtaatagt gagcagattc aggaggagac
    22261 agaatcttat gccgatcaaa gtgaaggttc tagctcggat caggggacat ctcgggcgag
    22321 tcaattcaca cctgccagta ccctagattt cacccctcag gcagtggatg acccccagag
    22381 ctcgagtaca ctctctttga gaaacctgct cccattgtct gtggagcaag aaaagatgta
    22441 cttcatgctg gccaccgtgg atgatccgac catgtataat tgcaccatcc agtacgagct
    22501 gcacggcaat ctggatatgg aacgctttaa aatcgcggtc attcacgtcg cgcagaggca
    22561 cgaatcactc cgaacagcgt ttgtcactca agctgccgat ggcatgcccc ggcgagcaat
    22621 tttagaaatt tcgcaaatcg gctggtggga gcggactagc ggtgatcctc tggaagcatc
    22681 ccttgagttt tcccgggtcc acagtcacga gtacgacctg gccaaagggc agagtatggt
    22741 aatatctatt ttacacacca gtcttcagca tcatatcatg acatttggct accaccatct
    22801 aatcatggat ggagtcagtt ggcaactatt actacgcgaa tttgctgccg cctatcaaga
    22861 tccagatctc ctggcccccg tcatctcgca gtacagtgca ttctgtgacg aagcactcat
    22921 gagagccgct tcaaggaacg acgcccttga acgtccaagg cttcttgaaa cagcatcgcc
    22981 tcttccttta ttcccttttg cccgggtgag cttccgccag gttcacacct gctatgagac
    23041 gattcaggtg agttcgcagc tggatgcagg cacatctgcc aaagtcaaag ctgtgagctc
    23101 ccgtactggt gctacatcct tccattttca tgtcgctgct attcagttgt taatacagaa
    23161 agttctcgac atcggcaagt tcatgatggg gataaccaat gccaaccgag acaaccctcg
    23221 cttcgaaaag gtaattggac atatggttga ggttgtgcct ttgtgctgtg agccgcagag
    23281 cagttgtacg ttcacagacc tgctgcagga tactcgagct cgagtcttag cagcactggc
    23341 ttctcccagc gcatcacaaa agccaatgtc cgctgagcag atgcacacca cggaatgcaa
    23401 tgtggcagtg aactatatcg ccaaattcac ccaggatatc cgttttgacc aatccactct
    23461 aaaatattcg acctcacagc tcgctcgaca accctatgac ttggtattca cgatccgtga
    23521 gaatgaagat ggaacaatgc tactcaactt tgaggcccaa aagtatctct attatgagaa
    23581 agaccttcgt attttaatgt cgctgtacac acagctgact gagacttttt ccatggggac
    23641 agagtctcgt ctcgagtcct atgaatgcat tgcagcttct gggatgcctt ctcttcatct
    23701 gcaacaaggg cccgtgttgg accatccttg gtcaggatgc ctgaccaagc gcatcaggaa
    23761 aacgataact acatacccgg cggatctagc catcaaagat gactccggga tgcgtcttac
    23821 gtatgagacc atgcactccc gaagtctctc aatcatgcaa attctgctgg aagcaggggt
    23881 cagctttggt acgccagtag cagtagcctg tggaccttcg gtggataccg tgtgcaccct
    23941 cctggctatt tggtggattg gtgcaatcta tatgccggtg gatttgatgc aggggcatca
    24001 gcgcctagct catatcatcg acgccagccg acccgcggcc attgtgtgca agggtccact
    24061 cggccagctc gaaacctcgc atatcgcccc ggtcattcaa ctcccccagg tcctccaacc
    24121 caccactctt ggccatcagg actatgcaga tgaaaactcg ccagccgcct tgctccacac
    24181 tagtggttcg actggggtgc ccaagggtgt tcttctaagc catcggaatc ttcgatgcca
    24241 cttcaatgcc acggagcaag cattcccgat tggccggcaa gtggtcttac aacatagttc
    24301 gcatagcttt gatgccgggc ttttccaaat tctgttggcc ctcctgcacg gtgggacatt
    24361 ggtcatcacc aacaacctta aagagcccgg tcagctagct gaactcatgc ttcgcgaaca
    24421 tgtctccgta gtcacagcag taccctctga atatgccctc tggattggcg aggctggtca
    24481 attgctgagc gagcttggct cctggcgatt tgcattctgc gttggagaga agctgagcag
    24541 ggccaccatt caggcgtttg ttagccttgg gcttccggac ctgaccttga ttaacgcata
    24601 cggcccatgt gagacaacta tggcttgcac aatgggggtg atagattacg aacgcgtcga
    24661 tggggattcc cagagtgtct ctatcgggga accgctgtca tcatatggga ttgcgattct
    24721 aaattcgcag ttaaagtccg ttccacaagg gtggccgggt gagatttgca ttgccggtgc
    24781 tgccgttgct ctcgggtatt tggacgttaa ggacgaagag ggtcgcttcg tcgaactaga
    24841 tggcgttcga gtttatcgga ctggggaccg tggccgactg cgagaggatg gatcactcga
    24901 ataccttggg agagttgatg gagattcgca attaaaactg cgaggtattc gattggagtt
    24961 ggacgagatt tccaatgctc tcctccaagc gtcggcggga gcattggtcg atgcagcaac
    25021 cattgccaag ggtgatccag atgacctata tctggtcagc ttcgtagttc tatctcgcgc
    25081 agtagagata gaggataaca ttgacctttt cattaagcag ttactaaata ctgtggcgct
    25141 acctccgcac gcaaaaccgg cccaagtcag tatcgtgact aggattcctc tgacttcaag
    25201 tggcaaggtg gacagaaaag ccctaggtcg gcttcccgtc ggtcaatccg ggtcttcgtc
    25261 ggaacaacca gtgctcgaaa ttatcgaacg gaagctgcta gaaatgtgga aagagtatct
    25321 gccctcaact gggctaccaa tcactcgaga aactagtttt ttcgagctgg ggggcaattc
    25381 actacggctt ttaaaacttc aggcacgaat ccggcgcgtg accggtatca gcataccgat
    25441 cactgagttg ttccagtcgt ccacattggg ggaaatggct cggttggctg gaacggtggt
    25501 caccaggatc agagcctcct caaaagcgat tgactgggac tctgagacag caattcctga
    25561 ctacctggat cagatcaagc ctcttcccac gcagccaaat ggagctgttc gggaggtgat
    25621 tctgacgggt gccacaggat attacggaag ggcaattttg gaggcgctgg tagagattcc
    25681 gtctgtggct cgcattcatt gcattgccat acggcctgct cccgacggtt ccccgcgtca
    25741 agaactgccc gtcaaatcct cgaagatttg tctctacagt ggcgatctat cggacccaac
    25801 atgtgggctc aatgctgtgg atatcgacaa actgacacgc accgtggact gtgtcattca
    25861 caatggggcc gatgtttcct tcgtcaaacc ctatgctgct ctacgaaagg ctaatgtcct
    25921 gtcaaccaag tacttgttct ctctctgtct cgcgcgccgt atctcttttc attatatttc
    25981 cacggccagt gtgaccagcc tttcggaacg tgatacgttt tccgccgcat cagtggcggg
    26041 atttcccccg ccatcattca acaatgatgg tcacaatccg ttggtgtcgg gctatgtagc
    26101 tagcaaatgg gccagcgagg tattcctcga gcgagcctgt gcccggttct cggatctcat
    26161 gccagatgtg cacatctatc gtcccactag tatcaccacc gccagcagcc cccatgaatc
    26221 accgtccgat gcttctgcgg gggatacgaa tatcatcggc gcaatcttgg atgtgagtcg
    26281 gttcctgcac gcagtgcctg atactcgaga ttggagaggt tatatcgacc tgatcggttt
    26341 gaacggtgct gtcgaatcct tagtccggaa tatcaccacc actcgttcca cggccttacc
    26401 gtcagctctc aatgaggcat cgaaggagaa tgacggctta ccttgccaaa ttcgctacat
    26461 gaatgtctgc ggtgagacac gcttcaaggc tagtgagctc agggaattca tggaagggtc
    26521 tgatcaagca gcttatctac aactaccatg gggagtttgg ctggagaagg cccgggcagg
    26581 cgaggtgatt gatgctgggg ttgctgattt tctaggtgag tgggaagctg cgactgctgc
    26641 cgactactgg agaacatcgc cctcttctgc gcggtctcca ttcctgctac cttggttgga
    26701 ataaaacaga acagaacatg ggtcaaacag ggacactcgt cagtggcttg cgtgatgcag
    26761 aacggtgtaa ttgtttgcat ctatgtatgt acttgaagga ttgataccaa tcataaaacc
    26821 aacttataag attcttcaat gaaacgtttg cgtcggatct ttgtacatat tggaattcta
    26881 atgctgttat gatggttcgg cttccttatc acggctgaag ggaaaggata ccatgtcccg
    26941 atgctctctt ccaccccaac atcatgtatg tactttattt tggtgaagag cggtagtcgg
    27001 acgcagaaga ggaagatcca taaaccccac taggggtctc gataaaactt gttttgtgct
    27061 tctgttaggt ggttgtgaat tataagtggc catttaggta cttgttgtat ctgcttcttt
    27121 gtgcattata tttaagaatg gtatgtacat caatcctttc tctctctcct gagagaaaca
    27181 tgtataaaag ccggtgttga ataatctact actccgggcg tcttccagcc aggtgtaatg
    27241 taggatcgat catgtcttca actgtaagat tcccgtgtcg tccattgttc cgtgtatcag
    27301 cccgatatgc gcatccccct ttatcaattg tgtaaataga taggtaggga tattaatgca
    27361 ctcaccgatg acggcccgga aacggattac tgttagacgg ttcatctgca cacaaacccg
    27421 acatgattag taaccgtaga gttaagagtg tgaagaaacc aaacaaaaaa tccccaatca
    27481 tgggaatgat gtgtgataca catacacggc atccagcaca aaaagtaata agcggcggag
    27541 aagaatgaca ggatggcgaa tgcgacataa catgccgcgt agagcatcac cacccttgac
    27601 tttggtcgtc cattactatt aatgctatca tcaccactag cattgctcag aatctccgtg
    27661 tcatcgtcat cgtcatcatc gtcgtgttgc ctataccccc ggtagggctg acatttctca
    27721 atatcgggag ggtgattagt tggactgctg ctgctgctgc tgctgctatt gttgcggtag
    27781 cggtggttgt agttgtactt ctgcaccgta gtattttccg aatcaatgga atcttcttct
    27841 tcttcgctga gtcgcggtgg attaagtgtc agctgatggt agtacaatta attatacgta
    27901 ggtaggtggt atagggatgt agtagtagta gtagtaatgc tattgggtac attccccgta
    27961 tgcagggtcg ggatggattg gctaccaatc aatccctgca tagcggaaat gacaatcttg
    28021 gggtaaaagt gattgggttg aattgattgg agtagtaaag cagataagcg caccagataa
    28081 atcttctgag tggctaatca gaaacaaaaa aaaaaaaaaa aaaaaaagta aaataaaatg
    28141 aaagtaagac ttaagctgac tgactgacct tggcctcttc aggggaattg gtatgtggcc
    28201 gttctgcatg cgactcatct caccaaaaca accacgtaaa tcgtaggcgt cagtcagctc
    28261 ggaataaggt tcaagaccgg cgtatccttg tgatgatgac tggagctgag gaaaggggac
    28321 aacatttcgg agctgggaat agtagtaata ataataataa ttctgaattt cattgcgcaa
    28381 gctattattt acccgtagcc cctgtaaatc cgtagcgatg cgggcgtttc agtctaggct
    28441 cgttagtgaa ttggttagtg agtttgttca cttgagggcg gtgatgagtc agccgttcat
    28501 tggacggggc ataaattggg ttttatgtat catttaaggg ggtcaggaga tgggatgatg
    28561 atgatgatga tgggtggtgt ggttcagttg gtcagtgagt ggacgggaag gagatttctt
    28621 cattgctatt tacagatatg gatcatccca gaaggctgaa gaacttgttt ttttgcaact
    28681 gccactcatt ttagccgatg taacaacttg gccagcagaa agcacttaga tgtcatgcaa
    28741 ccccctggcg agcgtatgtg ccacgagtgt caaaaccaag ctacatgcta cattccatgc
    28801 gtcggttgaa cccccttcat gctgagggac cgccttattc tccgggcgac agctcggttg
    28861 aaaccttatg gcagtttggc tcacggttta accatggttg aaccacggag tagcaacacc
    28921 tctggtgtgt cactctacag gggttcccag aacgctgaaa acggccactg ccctacatcc
    28981 ctagctaggt cgggattgaa ctcggtactt ttacaatgca tggaaaggga aagagccatg
    29041 caggaatgag taggtcattc caagattaca agtcaaatgg gaaaaaaaaa taaaaaaagc
    29101 atccatttct acgatacccg gacacaatcc gctggtacgg atcacggcag taattgaagt
    29161 gttaccaatg agaaatcgca gtgactcgta ataaggctcc atttaccgag tccccaacag
    29221 gcaattagca gcaacggcaa ggtccaccac ggtggtacct gcagataccg tgctcgaata
    29281 aggtactgat agtcgaatgg aacctggtgg cttccttgac gcttcgggag ggcaccttga
    29341 cttgacagct tgacggacag ctttggccaa tgaccacaag ggtggaggct ttcacaagat
    29401 tgccttaaca cgggtcatgg ttggaagtta tccacttggc caaacggcta attctcgccc
    29461 gaggttcggg atcgcgaaat ctttcctgtc gtgttcctgg ccgatgtgtg tgcgtatggg
    29521 agggagggag agagtattgc agcccaagca acgttaggcg atcctgaata gaagccccaa
    29581 tgcgaaaagt aggctcaagt aagtttcgta ctagtcaact ttgtgctatt tagcaaagtt
    29641 gccaagctga attctatgca ccgcattggt atcaccattc tcccccggca tgtgacatgt
    29701 ctgcccagag tcaagttcgc ttcaaagtac cgacccctag tgcagcctag ctgccaagca
    29761 agatgggccg caatttaaaa gtattttgaa tgaggaccga caatcatcat tattgggtgc
    29821 ttatgggagt tcccgattgg cgatgaatga agatcgccat gcccactggc atgaataaag
    29881 gaatcactcg ggagtgcaac agggacttca attacttact tatgactgga tcgcccatta
    29941 atcaacgcca aagtggttag ttgactattt tcggaaggag ctcttccctg ttgggatcca
    30001 aagccggccg ttagaacttt agaaaagagg agaaaagcgg caagaccccg gcctgcattt
    30061 cccccggaat agaaaccacg cggtattccg gcctcaaccc tgacgagacc gctgaggaat
    30121 tggccaatgg catggggtgg ttgcggtcat tggaagatac aattgcctaa gtaataaggt
    30181 aaggttcctg taacctgcgg atgcattgcc gttacggagt atccagtatt acggagcgat
    30241 ttcccatgca gtttccagga cccccaatcc agccggtgga gtggagtcat atatacgaac
    30301 ggtaagagag gccaaaaagg taggggccgg aggaggggaa aagggaaaaa aaaagggggg
    30361 gttcaaactg cagaaggatt gttatgggca aaggcttgtt tggcgtttgc ccgtggcagc
    30421 ccattcacta gagatgcttc aactaaattt agggtctgaa ggatgggtgc aacattcaac
    30481 tattgcatcc cataaaagtt gctatctgtg tgcgggtcaa atagacactt aattctgtag
    30541 agtactttcc ggctggcagg caactaactg tctccgtcaa taagtttgcc ctggtctatg
    30601 cgcaaagcct ttttcttttg cctttctgtc tttctgtttc tggccatgca agggggtcgc
    30661 agtgcaccgt gaccaagtca atggcatgga aggagttcaa tgcgtcctgt caggactccg
    30721 ctttggttgt ggggtcgatg ggcggcactc gaaactggtg aaacagacta agaatcccac
    30781 agaggacgag ggggtgaagc acgtggttgg ggcgcgcaac cagtcgtatt taccgcgtat
    30841 cgtatcttcc cagtatgtat cgttactctt cgtgtgtatt acacagagat ggtatcatct
    30901 gcctgttatc tgttgtgggt aagcctgaag acaacactcg gagtatcttc cacaagataa
    30961 catggtccat catcagactc attcgataga aatagaacgg atgtggatgg ccatccttgc
    31021 tgtagatctc ttctaaaagg aaaaaaactc ccaagacacc gacagagcct agacccaagt
    31081 tagcgatggg ctaaggtttg tttgccattg tctataatca ataataattt tgagaggggt
    31141 gcttcaacca ccctagcggc tctctctggc cctaaatgag gcagcatatt gcccgaacca
    31201 tggtactcat cccgcgaact atcccgcggg aagcctgtct tgcacgtacc gagttaagat
    31261 ctaacgacta aggtatggcc atgactccca gggacactcg tggaacatga tcagatcaag
    31321 agaatgtgca cacccctatt cgcatgtcag gtgcacaacg gcgaaaggga atacgtccag
    31381 cttcgtttca tctgttcggg gttcggagga aatccaaatg cagaaggatt ttcgagttcc
    31441 actccgacat acttctcgaa ggagataaag aatgcgactc gggacgagct gctctgagat
    31501 tggatggaga ctgttatttt ttctgcgtcc gcctctcagt tctgtgggta ggtatgcagg
    31561 cttctcctgc attcgaggac gaatcttgga tagcgccgat gaccagcata tgatagatct
    31621 catggggaaa gacgaaaaag caaacatcca cacataaatg cgtctgctag actagactgt
    31681 gctcgccact tccgctacag ctgttcgctt ggagggtgtt ttcctgtggc taaggctaag
    31741 cgcccatctc acctccactg attgacgcga cggcagactg acggactgct gattaaagct
    31801 acccctgcct tagtggcccg acggcgtgtt ggccggcggg caagacgagt ccggaaaccc
    31861 ggaagaagcg aaagtgtctc cacattccca ttctccaaga agaagggaaa aaagaaaaaa
    31921 gtaatgcagt gcgagcacct ttccacggcg atttctggac ctcgagcctc gggtggtcaa
    31981 tgaacgatac gatctcccga ctcatgacag atcatgatat cgtaaataga gtttcacatg
    32041 gcatggtcct acccctacat aggtacgttt cgcattgatc cgaccgtgat gagatcatgg
    32101 gggatcttga tgatgaccac agaaccacag aagcaatcat gcaactatcg ctcaataatt
    32161 agacaaccat tgcaaatgcc tacttttcca acacttggaa ggaaatcgca tagctgtgga
    32221 gccaagtttc tgctagaact cagccgcaga ctcatgacag accaacggaa gataccgaaa
    32281 ttgtcgcggg tgagtttgaa aagaagccac ttgcgtagat aaagttctac agtaagctta
    32341 ggcaggttcg aattctcagc cctctatttc cctttgtttg tgatgcatcg cagagaatgg
    32401 cgatgatcta tgagagcccg aggcactagt tcaactcaat ttcccgaatc tttccttggt
    32461 ccaagagcga tgtacagtca gtgttttcta tagaccgacg gatcaaagac ccgggagctc
    32521 gaacatcgat aacactatca atagttcctc taccctctga tctaacaaat aatagtagac
    32581 aatttgatcg agatgggatt tgcaggcttc attcggactt cgtacttcgt accaaaccaa
    32641 tgtccatgga agcagatact actcgtcgat cggtgcatac caatgcatcc gattcgcgcc
    32701 tcgtggcgtc gtcgttcgct tgcatggctt ggcagtcgca gaagggcacc ggtgggaaca
    32761 tgactcgggg gtctcattcg ccccagagtt agagacatca caaggatgca tagcgcaaag
    32821 tacaaagcac tgaacactgg aactgatgct gatgtccagc gaccgtgaga ttgggggcta
    32881 aactaagttc ccaatgttta cgatccttgc ggttgaaagt gtattgagtt catatagatt
    32941 catataccca gattaaagga tggcggtcgg aaccatatcg atgggtaaga taatgtgtgg
    33001 cacgtggatg atggtggacg tgagaaggac atacttagtg ggagcaatgc tgcatttttg
    33061 agaatagtag tccatcttcc atccagatta attaggaatt aatttcacga agacccaggg
    33121 aggaaggatc tatggtcaat ccattgttca tgggcccgag ggtcaacgga gaggccggaa
    33181 cctgactcga acaagtacgt tatccctact aattaatagt caactgcttg gatatttccc
    33241 cagcaggaca ggcgttggtg ctgcagagaa taaatggagg atacggagaa ctccgtacca
    33301 aaccacgtat atactgggta atgacgtcgt ccggtattat aacgtgttgt gccacccgta
    33361 actcgcaaga ttcttactta ctacttactt agctgacggg cggtaaaaag agcactggac
    33421 cttaaatgac tccatttcca atcggctcga accaggctaa gagcggacga agaatgaatg
    33481 gagccattca tccggggtgg gccagcattg tttgtccaca gccagtgaga taagggccag
    33541 cccgtctact ttgtaccagg aagctcccag ccgggatgct atcacggact aaacaacact
    33601 aagaagccaa gggcttacgg ctaaggccct taggagacgg tagccacagc cggctagtcc
    33661 ctttctagat tcccagaacg gggcccaatg cgacgccgga aatctttcac acggttttca
    33721 cggtaataca ggcccccctc cccggggtgt cagggccact cacagccgaa ggtccccagc
    33781 aggatgacta cgccgaaggg gaactaagcc ggactaaact tactagcagc tcaactctgc
    33841 tggctccgtg gcccacttcg atcggacttg atggattatc gaacgaattg cgcgacacct
    33901 ccgcgaccaa cattcccacc agttactcct ccttccactg ctacctctaa actactacta
    33961 ttattattac cactactata gacctgcgag tctcccagac tgtccttact ctctcctctc
    34021 tctcctcctc tctttctccc tcgctccctc tctctctctt ttttcctctt ccctctctct
    34081 tgctttgctt cacgccctgg tcttccgctc ttttgcttgc ttcggttgcg atacggcgga
    34141 ggatgtacta atctcgctcc cccatttcct acctacctcc ctccccatct ttcccctcac
    34201 ctgagcgtct gcggtcagca tcttcgccca ccaccattac acgaaaaggg gaacgcctcg
    34261 aggctgcggt cagcatacct agcgaattct gccccagcat ttaatttgga cgacttcctc
    34321 cgtttaccga cacctcaatc ttgaaagtcg tgcgaacttc cgaaagccct ctcacttccg
    34381 cgatcgaccc cgtctcactc gatacctgtc tgaaccacca ctcaacctag cctgtcgagg
    34441 gaacttccgt cgtcacattc cttaattcga ttccacttct cgcggatatt agaaagccct
    34501 ggacagctgc gctgctcgcc attcaatttg gatatcgttc tcatacaaag cgggggtcac
    34561 tttgcgacag tcgtattgga acactccttc gactcccatc ctatccaagc tgttttgctt
    34621 tggaatagaa aataccgcga cgtacgtaca gtgaccgagt aacgttcgac tagacgttat
    34681 tccagctagc gacatgttct aatttgcgcc attcgggcgg gtttagtcaa aagatacatt
    34741 tgtctgtttc tcgtgcttgg tattacattc tgccttgggt aagttgcgct gtttactttg
    34801 tcgcctcttt ttcattgctc gagacctcgg gtctctctgg ttgacgtttc acacatgtct
    34861 caaagagagc cttccgtttg gttaactgcg gggtctgggc gtatccctga ttcagcctta
    34921 gactttattt gtgctgcgtc tattcttggt tacttcgcac agtataatca gcaaagtact
    34981 gactcacttc cagacaacat cgagagtcgc ttggtgaagt aaaacacgtc aatcttcaat
    35041 atgggctgca tgagttcaaa acccgtcgac acggcggata aagatgctgt tcaacgaagc
    35101 gctaggatag aaaaggttct gaagaatgac aagaaagtaa tggaccgaac gatcaagatt
    35161 ctccttcttg gtaggttctc agacgaaaca actccaattt gcagtcgtgg aaccggagag
    35221 tactgatgcc attttccgta ggtgctggag aatcgggcaa atcgacgatc ataaaacaaa
    35281 tgcgaatcat acattccggc ggcttccccg aggacgaacg acgccaaaca cgagctgtca
    35341 tctattcaaa tcttgttatc gccttcaaag ttctactgga tatcatgcgc gccgaaaaca
    35401 ttgatttcca gctcgaaaag acaaaggtaa cctcgtctgc tcggttgtct tgcaattttt
    35461 tcatcgcaag cggagatcga aatctttcca gtatgtgtgc taactcagcc cgttcttgat
    35521 cagccgttag ccgaatatgt agacaagctc gagcctgatg tcggttccga cgaggcattc
    35581 tcagatctca aggttcgcga tgccctcaga gacatgtggg acgacacggg tgttcagaaa
    35641 gctgttgctc ggggccacga gtttgctctt cacgataact tgcattagtg agtgccagga
    35701 accttctttt gagcaaacag gcaattcgtc taacctttta gcttttttga ttcgcttgat
    35761 cgaatattca ctcctgggtg gcttcccgac aaccaggaca tgttgcaggc tcgtttgcgg
    35821 acaaccggaa ttactgaaac tctctttgaa ctcggtcaaa tgaacttccg aatgatggac
    35881 gtcggtggac agcgatctga gcgaaagaag tggattcact gttttgaagg tgtacaatgc
    35941 cttctattca tggttgctct atctggttat gaccaatgtc tcgtggagga ccagaatgcc
    36001 gtacgttttc ccctgtcgcc ttcgtgaaag cacttgatct aaccgttgtt cccgaatgtg
    36061 cagaaccaaa tgcatgaggc aatgatgctg ttcgaatcct tggtcaatgg cgaatggttc
    36121 aagcgcaaac cgatcatctt gttcttgaac aagatcgatc tgttcaaggg aaagctgcat
    36181 gtttcgcctg tctccaacca tttccctgac tacaatggct ccaacacgga cttcgatgcg
    36241 gcagccagat actttgcaga ccggttccgg ggcatcaacc ggattcccga tcgtgagatc
    36301 tatatccatt acacgaatgc taccgatacg acgttgttga aggcaacaat ggattcggta
    36361 caagacatga ttattcaaaa gaatctccac accctcatac tataaggttg tgacctttgg
    36421 aacgatttga atttttacga gcgagtacga ggcgtcagcg atgctcaact tccgttcttc
    36481 ccctgcacac gtcaagcggt gaaagcacgc ttgcttttct tcgactattt ctattcactt
    36541 cactttatcc cttctcttcc tgtatgtttc tttctccttg tggactcctc gtctcagctt
    36601 ttcattcctt tcaaaagctt atatgttttc tccggttcag cgacgggtgc atttcttata
    36661 taatgcagat tgataccata taccatatgt tgtttgcgtc catgtctgcg ctttttgtca
    36721 cacctaacga gctcttttcc attttcctga gctgaacctt tccgtgcctt ttacgcctcc
    36781 catgtgcctt tccttttctt cttacctgtt gacataatga gcccccaccc accctatcat
    36841 ttgctcgtgt cacttctggc agctctcact tggagctgta tcttctgtat ccgatcattc
    36901 aggctctcat aagtataatt gcccatactg taattgttcg gctcaagtga ggtgagcatg
    36961 gaacgaacag atacccaaat caaagccaat atagtgtctt agttcttgca aaatagtagt
    37021 tgtcaccaaa taatcagtgt gctcggtggt agtgcccgtt tatatcaacg gcgataggaa
    37081 attatgcagg ctgatcttga tcatagatgt ggacaaagtc atgtgaaatt actctgtaga
    37141 tagtttcctg caattccagg tcacctgatc tcatttggtg cctgaggcga caggtgactt
    37201 acataatcgc cgagttccgc atgatcggct ccaacttcga tttcgcctct tcgttcccga
    37261 caacatcgtc acccagcttc tgggctttac gacgtcggaa aatgctgtcg tcctcactgc
    37321 gccgggctgc atgggctcct atggggccca tcgccggtat atctcgcgca accagccaaa
    37381 gtattactac ctccgcgaac ggcctcatcg gctcgtcaca acaacatgtg cgtcaacgcc
    37441 gatactcctc ttcgtcctcg aaacccagcg atggatctaa taaagtcgat tcttcctctc
    37501 agacgcctgc gaagggagtg aattctgcag agaaacgtga ggggaaggct tccagacgga
    37561 ggggcaagga tagcaacggc cgcaatggct ccaagcagcc gacggctttt tcccgacttc
    37621 ccagtgttcc ctctacccaa catctccagc cgcatggtta gtcgccacaa tcctagtaac
    37681 tgtgcttgta ttactagact atgatgcgct aatcttctcc atttggtcca gacgttcacg
    37741 tcgcctcctt cttttccatc caccgtccca tctccgtttc caccaccgtt cctccgacct
    37801 cgacccccga agcgttcgac gccatcttca ccgcaaagaa gccggccaag cctgaggtgg
    37861 acgatgtcat cttcaccctc tcctccgccg tcaactccat ggagaactcc gctgcccact
    37921 ccggcgagca ggagggctct ctgcagtact tcgacatgga aggcaaccag ctggatggca
    37981 tgaacctttc cgatctgaaa gtctccgtcg aggaactcac gaagcgtctc cgtcccttcc
    38041 accccctccg ccgccggttc ccttcgacga agcgaaggac atggctttct ccgagttcga
    38101 ggacgtccct cgggagacct ccagctactc caccgtcctg accattcacg agtcgataca
    38161 ctctgatggt cgcaagacct acgaggccca caccggtcct ttcgtgccct ccggtgagat
    38221 ggaagctccc ggtgccattg gagagagcga ggccatcatc gatgtccccc acaactccgg
    38281 caccacctac atggagcgta tccgcaacaa ccgcaccatg cacgccatta gcaccaagag
    38341 acgtcgcaga ctgaagatga agaagcacaa gctgaagaag ctgcgcaaga ggacaaggac
    38401 tttgagacgg aagcttgaga aggcttgatt gattctttca tcatcagaga ccattaccat
    38461 ttgctgcagc tatttttttc tttttgctac gctacaatcc gaataaacct tcctcattta
    38521 atctcctcgt ttatctactt acatacttac aaccttacct ccccatttcc tctgcttcac
    38581 agagaagtca tcctagactt acgcatctga agctttgcgt ttattgctat gctcttcgca
    38641 tgtatgtgtg tgtgtatttg gcggcggcca ctgatgtgcc tgtccatatc gcatatatcc
    38701 ttacggcgtc gtcttgagtt tctttgacct ccttctttct cttgaatatt tggatgttca
    38761 tcgcattttg tttcgttcca tagacattac tttgtatgtt acatattgct atcctatcta
    38821 tatgccctgc ttgctcttgt gcaggtcagg tgcaatggta tctatattgc ttgactttgc
    38881 tcagttggaa aggtctatgt actgcttcgg ttcatttcca agacggtatt ttctagataa
    38941 cagaatacga gcaatctgtt gggtgctata acttagtagt acattcgcca cttggtacat
    39001 ttatgctata cggaaggacc acatacatga cttccagggc aggataggtt agaaagctaa
    39061 gtttgtacca aaaggatcct taaaactagc aggagaaaac atataagcat tgcaaagcaa
    39121 gtaatcctat gatccagctc aaggatacaa aagagtaagc gactcccata aagtacataa
    39181 tttcaaaaga ccttcaaaaa ccatgcaatg tatctaccac agcttcccac cttgtcctag
    39241 tctacaaact tggctagcac atccaattat gtcttgtcct ttgttatttg gggggtggtt
    39301 ggatgaaaga gaaagcatat gttatataac gtccgttttc tctttccaat cccccagcaa
    39361 tccacttctc cccatcccct ccagctgtca tcgggacaat gacgggaacc gtcattgtcg
    39421 gcaaataaag tctgaaaaca caagtcaaaa taaccgcatc acgttaacac atgttgagca
    39481 acccgggctc tgttcatcat atccgaggat atagggtggt tggcatcctc gggcgggtgt
    39541 tcacttgggc catttcgcgc ggaacgaagg agggttcgtt tagcaagtgg cgtcgatcct
    39601 cgaacgggag ttcatcagaa gagcaacgat aagaccgtac agacctgtaa aacatccttg
    39661 ttagatgggg cagaccaatt atatcgctat gttgttgtga ctcacccaag acttcagcga
    39721 aaatgagaat caaaatcatt ccgacataga gacggggctg ttgagcagtt ccacggacac
    39781 ctgcgtcacc aacgatacca atggcaaaac tagagatact gaattagtcc caagcttacc
    39841 ggaactgaaa ggtgccatgt tgagaagctt acccagctgc cataccagcc aaaccgacgg
    39901 cgagacctgc tcccagctga atgaaaccag tgtacaaggg gaccttctgt cccaaatcgt
    39961 ttgcaatcag gaccgacacg accagaccgt agataccaat gatacccgcc atgacaatgg
    40021 ggacaatgtc tgtatcacga gattagtatc acatcatccg aaattatatg cgatggcata
    40081 tcccagtggt ataaagctct gtgaagcttc cacgtactct tgacgatcag gtcaggtctg
    40141 aggacggcca ttccacagac accgacacca gccttggcag ttccataggc agctccgaag
    40201 caggtgaaga cgatggccga ggtgcagcca agggcaccga aaaagggcta tacaagttgg
    40261 agatcagtta accgtgtcga gagatgcttg ttcgatggca gattctccgc ttgatgcaac
    40321 gaagccaagc taccttgagg gtcgcttgga gctcgatggt gtcatcggtg agggtgggat
    40381 cacaagtgac ttactgcgta aacggggcta tcaagtccat atgtcagtat atcaagtcga
    40441 gaatcatccg taacattatt aaagtcgaga tacaagaggg cacaatggtt gggatgctgg
    40501 gaaaaggagt aggtgaggtg attacgtacc aaagttcggt ggccatcttg acagatttgg
    40561 cgaccttgcg ggcgatagaa gatggagtga aactatgaaa acagccgaaa ggaagagtga
    40621 cagggcaggg acaggccgcg tgtaaagcga tgtggtgatg ttgaggcttg gggaagcgag
    40681 acggagatga aggcgtgaag gcgaacacgc tggaggcttc ggggacgctg accgaccacc
    40741 tgcgtcatca cgtgatggcg gcttggcgct ggcccgtcgg ccgcgcatca cgataaccag
    40801 cttccccacc cagtcggtga tgaagcagca gtcgtgaaac agatacagct tgatgtaaaa
    40861 atataatatg tactacttgc tgtgctcact atagactatt ctctctcttt ttcatatata
    40921 gggctatcgc actctacatt gtgttcgagg atatcggagg tgtccgctcg agagataact
    40981 gaattacgaa tcaccgtccg gttttcctga tagaagaata acttcatata gagtgagact
    41041 gattgtatac ggtatagagt tgtaaactac gaagtctggc atctaagcca atatggctta
    41101 tatggcaagt gcgcgatact caaattggct tgaagtattg agataacgag acagtgatgg
    41161 ggaaatgcgg agactgcggg agtagctgcc aagccgtgat attttgggtc gtacagaata
    41221 gatcaagacc cctacctcta cattgtactt ctcaatcctt cgtcgcccat gtggcaaaag
    41281 atattcaatg cagcgctact agtgtctctg gctcatcaca gacagggtcg atcttcagtc
    41341 atgatgtcct tagattatat ttgtaagctt acttacgtac tatctatcac acaaaaagga
    41401 catgactgat agctaggtcc aaaatgtgtg cgctcatatc ggtctggtca atatctcctg
    41461 tctgtctttg cgatagggat gaccttatga aagctagtat gtctacacgt attgtattca
    41521 tacctttccc ttgtatatca tcaccgatta ctttaatcct ttccgccatc gcgcctttcc
    41581 ttgaccagat ctcagacggg gatcggctac agagcggttc tgacaatgtg gttgaattac
    41641 tgcactacca taaccactgg cgagtattgc ttcgaaactc agtacgctag aattatttag
    41701 tagaccttct ctctgaccat cagatatcaa tcatggtagc tagggtgctt gcgcttcatt
    41761 atatatagta agcaaaagga agaagggagt gactacttag tggtagctat gggttgataa
    41821 ggtcactttc catcgaagcg ggaggccaga tgtggatttg aaagataagt agaaatctcg
    41881 tgcgtagaga acgtgcaaaa aaaaaaaaga ggaagcagca aaatattcaa gcaatacaac
    41941 tatctcacta cgggtgcagt tttctctcgt gtcttgccga caaatgtatg taacatactc
    42001 tttacatact ctttctacac ctcctggctc acaccccttc agtgaggcat accttttctt
    42061 ctctcgaaca ccatttctgg ccgaatgact gcaatagagg ctcttttctg ttacttggac
    42121 atcaagagtt ggaagcatta ttcatcacaa acagacgcag acgaagtcgc agatgcagtg
    42181 gggatactgt aggctcatcc tgggtactgt ttccacaaat cccacctgct tgctcgcaac
    42241 agagcagtta gagtgtattg gtatactctt cataggattc tagagttctt ggtggtccta
    42301 ggctgcataa ttcaagttgt gcccactaaa aggtactagg cagacgttga acgtgtaggt
    42361 ggagggtgtt actgcgcctt gcgggtcact cgaacatcta tatatatatc cctggcgaga
    42421 tgctgctgta agatagggct atgcatatat aagctttaga tcgaatagcc tggagggacc
    42481 caccatcatg ttagccaggc agtgcttttc ttacgttgct ggttaaagta tgcggggtga
    42541 ccaggatgtt tccttctaga aataacaacg acacagggtg gcttggactg cggtgatatc
    42601 gatcacatga tactgcgtaa tgtcgatagg caacttgatc tcttattttt atcaactcta
    42661 tttttattct tctcgctgag gctatgtagt agtgggatgt ctccgtcatg atcagcagga
    42721 tcctcgtaaa cattcgacaa tataagcaac cgttttgtca ggtcatcatg gcagacggat
    42781 taactcgtaa tgatgtattt gcgatatgcg aacgataaga catttcatta tcgaacacat
    42841 gacgtctaaa atccggctga aacgtgcttt agtccaatga ttatctgcat agttagcgta
    42901 ggcgctgacg gatagatgcg tgtcaaatga tatcactttg ctttttccct ggaaatgagt
    42961 ccacgctagt ctagacacta caaagtcaag taccataatg gggaccggta tctgtccgac
    43021 attgttaaaa gctaccggca ccgtgattcg tgcgagagga accgtagggc tggatggccc
    43081 actaaattta tgctgaattc cgtctcccaa acctcctaga cacgggagtc atacccctat
    43141 tctgcacaag ggattgcgta gggggccagc tctagtccga taaaagcagt aggtatgaaa
    43201 tacgatgtgc tggtccgtcc cacccagaac cgaagcccag acgcttggag ccctctgcac
    43261 agagtgattt agtcaatatt ggcggcgtct aacctaagac taccggcgcc tcgcttcagc
    43321 ctggtaaggt ggtacggtgg aagcgccaag cccctgccag gcaacaaaat aaccatgaca
    43381 aaggagggcg gagggaggga aaaaaaaaaa aggtaaaaag tcaaaatgta ggcaatggga
    43441 ggaaagggga aaaagagggc gaaagttctc cccttactgt tgaacaaaac ccagctgcac
    43501 cgcccgatga caacatggtt cagttccaaa attggaggag catcagccac gggactgggg
    43561 aggtacaaaa tacaaaacgt cgatacgacg caaaagtcac ccgccgagag tctggttgag
    43621 gtgagctcgg agccaatcag caagcggcca aggcatcagc cacagttcgc agtgaaaagt
    43681 atgacgtagc gacaaacatg cacggcgagc ggaaaaggat cgtcctgact atcgttgtcg
    43741 tccgccccgg ttattctaat tatcactagc agctattggt cttttatctt attacctaaa
    43801 ggcgtatccg ttgaataact aatgcggatt cgaggacagt gctttacgta ggaggcatag
    43861 caccatcccc cccggcggag ggtagctact taattttgcc gcccatcatt taagagtccc
    43921 tgtggtcccg ctcccttcct ctcctgattt ttcttgttgc ttccccatca ttcatctgct
    43981 cgcaatcaga tacaaccttc atctggtcat atacatcatc tgctcactac tctctcctac
    44041 atcaaactag tcaacttgaa gagatctacg tctccctcga ttcacaatgc ctttcactgc
    44101 ctcgtaagtc ttgcaacccc tcgcgacgtc atcttttggc gatttcctat ccagtcgcgc
    44161 gcatacctgg accttgacga gctggagctg tcttgggata gcttgcgatc ccaataatct
    44221 gaatgacgag agcatagtgt cgtgggtatg ctaacgccgt tgggaccata gggatatctg
    44281 caagatcatc tttgcgatca tcttgccgcc actgggtgtt ttcctggagc gaggatgcgg
    44341 tgctgatttc ctgatcaaca tctgtttgac aatcctgggt tggctccctg gtgtcattca
    44401 tgccttgtac gtggcccgcc aagtgatgga tttccggaga ttccgaggct aactcgtttc
    44461 gttcagctat atcatattca aatactagac cgctcctcag gcccgtcatt accgcccact
    44521 tcgattcaaa acccgtcgat tgggggaata acctcgtcct acctacgatt tcttatccta
    44581 cggaatcgaa gattcgaaat ttagcgggtc ggggtgacgt tgtcaacatc attagtatcg
    44641 ttccgcgggc tcccgacgag tctagcctaa tgcaaccccg ccaacataag cgccgtcatt
    44701 gggcggatgt ccagcatgct cagtgcggcg tgtgtttgtg acagggtctt gatcgccttt
    44761 tttttctagt tttttcccct ttgttcttat ctccttgggt tgtcattttc ttatgtattg
    44821 cgcatgatac cagctcaccg tgtcactggg ctttgctttt gtcattatct cttagttggc
    44881 agtgatcaga tttatgattg atgacaatgt caaaccaatt aatcaaccgc attctgggct
    44941 caaatcgtag ctgcttatgc cataagcagc attgtaatct gcggagtggg tatggggaaa
    45001 cacgagttgc cgatcgggcc attgaaagca gcccaagctc aacaaatccc gtgatgcgtc
    45061 tgtctagccg cgtttcgcct tttagtctag tgtcgacaca tctagctgga tctacactcg
    45121 cagttgtgcc tggttgccct cagggtcttc gaatcaaaaa tagcctaaag gtgcgcggtt
    45181 aaggaaacgg acctaattcc attgcttgcg ccttgaacct ctcggatcgg ctcatctgac
    45241 atcatgtgct gttcatatcg gcagggtcgg cgccaacacg gcgcgtactt caacgccatc
    45301 gtctacccaa aacccaatca tgcaaagcga cagacctcct gaagaactgt gtccatgagc
    45361 tacgtgtatt atgtttggga cagtgttgcc atgtttcgcc ctggcgcgta taggaggctt
    45421 ggactactga tttgggtctc gaaccttgat tctctctctt cgcagccact cagcgccatg
    45481 gcagaacgtg gtttgacgcc catgttggca gtatgcggta catcgtgctg gtccctgaag
    45541 tcgctccttc ccccttatcg cagccgcttc tgtcttgaag ttggtgcttc tccatgctgt
    45601 ttggaaacca tcgcttctcc agatcctcag tgttctttgc actctttctt ccttgatcat
    45661 cttaggatga tatcctacga ttatcaatga ctccagaggt tggattccct ctgtagcgtc
    45721 actttttacg tgcataggta aggtatcgac cctgtgacct cccgttcgcg actccttggc
    45781 ttgcattata cctggcggtg atagtctact aacccgaaaa cgaagatgct tttacaagat
    45841 gtttatacct gctggacggt tattcacgat aatactgttg atgctgacaa gtctcgccta
    45901 tggttcccag accaccaatc ctaccgcatc agcaacatct ttgtccggtc tgatcccaag
    45961 ctgtgcggca gactgcatcg aagaatttat aatctccgat tacccaaagg gcgcatgctc
    46021 ggagtgggat ctcgactgtc tctgtcggac gaacacgaca agcggctata cgcttgggga
    46081 ggcggcattt cgctgtagcc tttccttatg ttctatgaaa acagtcttca gcgccgactt
    46141 gtacgacatt tgcgactcgg tacctggagc tttgccacgg actcatgcta cgatcaccgc
    46201 gacagtgatg ccaacaggat caagtcccac gcaaaggact gcaacgacga cgacgacagc
    46261 gacggtgcca tctacctcca gctccagttc ggcctccaac actgggtccg ggtctagctc
    46321 tagtacatcc tcacaaccga caagtcttag tactgagcat acctcggtaa ctactgagac
    46381 ttttcaaagt cctttgacgg tttcaacttc gcagcctttt ctcacggcaa cgggtag
//
