LOCUS       ch1                    18638 bp    DNA     linear   PLN 04-MAY-2020
DEFINITION  Aspergillus niger strain KJC3.
ACCESSION   ch1
VERSION     ch1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Circumdati.
COMMENT     'Annotated using 1.7.1'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-03 01:23:18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 720383
            Orig. end    :: 739021
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18638
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[728935:729892](+)"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8553..9509
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..18638
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..18638
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            join(1..131,191..221,285..422,479..779,892..1937)
                     /locus_tag="KJC3_000391"
                     /product="hypothetical protein"
     gene            1..1937
                     /locus_tag="KJC3_000391"
     CDS             join(1..131,191..221,285..422,479..779,892..1937)
                     /codon_start=1
                     /locus_tag="KJC3_000391"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KJC3_000391-T1"
                     /transl_table=1
                     /translation="MHTIPITVSLYAFLATTFLFSCSAYVAQAPLSDDKCTETTVAILG
                     GGMAGIAAAQALSNASIDDFIILEYRDTLGGRVWHTDFGKDKQGKPYVIELGANWLQGL
                     GSEAIENPVWALAKKYRLKNTYSNYSSIRTYNETGYTDYRYLLDEYAQAYHIAARDAGR
                     ILTQNLQDQTARTGLALAGWRPRKNDMAAQAVEWWSWDWEDAHTPETSSLVFGIAGENL
                     TFNQFGKANHLVLDPRGYSTIIQNEALGFLPNPSDGRLRLNTRVTRIEYSPRGVTIHTT
                     NDNNKNSNTCIRAAYAICTFSLGVLQNKAVTFDPPLPSWKQTAIEKFNMGTYTKIFMQF
                     PETFWPTDTQFFLYASPTTRGYYPVFQSLSTENFLPESNILFATVVDEQAYRVERQSLT
                     QTKDQILNVLREMFPDKHIPEPTAFTYPRWTNEPWVYGSYSNWPAGTTLEMHQNLRANT
                     GRLWFAGEATSAAYFGFLHGAWYEGRDAGENVAALLQGRCVEDVSTTSTASGKEEKEEA
                     CGERVFYEQLNGTTPLDAYSRLNGWPAVSYY"
     tRNA            2079..2150
                     /locus_tag="KJC3_000392"
                     /product="tRNA-Arg"
     gene            2079..2150
                     /locus_tag="KJC3_000392"
     mRNA            complement(2573..4108)
                     /locus_tag="KJC3_000393"
                     /product="hypothetical protein"
     gene            complement(2573..4108)
                     /locus_tag="KJC3_000393"
     CDS             complement(2573..4108)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 73.2; E-value:
                     2.3e-22)"
                     /gene_kind="transport"
                     /locus_tag="KJC3_000393"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KJC3_000393-T1"
                     /transl_table=1
                     /translation="MATCTEKYSPTPTEVFQDHIASNESDTATLSWDDDNDPENPYNWS
                     VGRKWTLTCLAAFTTFLAMMNGTIITVAHFEISEHFHVNEDAFPNSYWPVTTWATGGAC
                     SALFILPLAEDFGTRPIFLTTYLLFICFLVPQAVAHNFATLVVTRFFAGGCVAILANTA
                     AGVVGNLWSTEWSRSIPVSLYILGYMSGSSTGPVIGAAIFHSLGWRWISYMQLIWFGAL
                     FPIYYFFLHESRGSAILARRARRNRKNGDETSGYAGSGDVSSRLNLHSLVVSATRPVIL
                     FSTEPVLFVSTLWSAFTVGTLFLFTQSVEQVFMGLYNWDVSQTGYVQCAIVIGECLGWL
                     VNFLSRKLYFASASRNTEVPGTPIPEARLYMAVVGGVLGLSGGMFIYAWTSYSSLPWIA
                     PTVGLALVGAGSVCVVTGVSDYVVDSYSQFSGSAMGAVAAGENVFSAFLPLATMSMYRV
                     LGYQWASTLLAFICLVLSLIPTLMFVWGKEVRARSAFMNEMANDATKKRSEVV"
     mRNA            complement(5897..7105)
                     /locus_tag="KJC3_000394"
                     /product="hypothetical protein"
     gene            complement(5897..7105)
                     /locus_tag="KJC3_000394"
     CDS             complement(5897..7105)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 281.2; E-value: 2.8e-85)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="KJC3_000394"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KJC3_000394-T1"
                     /sec_met_domain="p450 (E-value: 6.9e-55, bitscore: 182.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MLAASRIPVTYASLKGIQTQWLHNLHLKYGPVLRVAPNELSFIDP
                     QAWKDIYSSSPTEPQSMRRGSDFFRYLEDDDNRPSILAANEIDHPRIRRAYVPAFSRRA
                     LARQESILAKYGDALVERLSGIEGQITNIRNMFHYTLFDIVGHLHFGEELGVLRTGAHK
                     SWVHSQHRLVRAATLLSALAEFSWINLLFRSTIPWMSKWLRKAYFKPSNDLIDRRLQLQ
                     SDEPDLIGLAFRNSRSLSLTEKDIRANAHIMMTGGAETTTALMTALTAYLLQHPECLAR
                     LKNDIRTAFHDKSQVSLESVSNLAYLDACIKEALRLYPSVPGALHRATPAGGARIAGRW
                     VSGNTRVYIPIFAATHSPTHFWSPDKFIPDRWLDGADDPYQKDNKTAFHPFSTGPRGCI
                     GQE"
     mRNA            8553..9509
                     /locus_tag="KJC3_000395"
                     /product="hypothetical protein"
     gene            8553..9509
                     /locus_tag="KJC3_000395"
     CDS             8553..9509
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: TRI5"
                     /gene_kind="biosynthetic"
                     /locus_tag="KJC3_000395"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KJC3_000395-T1"
                     /sec_met_domain="TRI5 (E-value: 1.4e-26, bitscore: 89.6,
                     seeds: 3, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTKAQTAVSPDEFFKIITPFLNEIIPNIPPFAPDEAFYKAVFDKF
                     AAASGLPEDSIPHFVGTGEVLARCFYPSLPRDLQISIGVLTAYVFSIDDQCADPEFREQ
                     IKSYRSVFLGQSTTNLQYIKGLYNTLHDIVSHYEWYAGDMIIKSTMDFVSINIVEAEQT
                     GDFMVSPSTKLFPDFLRQKSGIGEAYAFFYFPGSDWGLGDYFTLIPDIAGIIEQLNDVL
                     SFYKESVLGNEPGTWVKQTCVCKGISEGEAFRERVDQCLGSIRRLRAASEGNPRLLKTV
                     NEFINGYPLFHLNAGRYKLDQFGSYHGWQGEKTAGGN"
     mRNA            17910..18638
                     /locus_tag="KJC3_000396"
                     /product="hypothetical protein"
     gene            17910..18638
                     /locus_tag="KJC3_000396"
     CDS             17910..18638
                     /codon_start=1
                     /locus_tag="KJC3_000396"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KJC3_000396-T1"
                     /transl_table=1
                     /translation="MAPILLSNNIRTPFRYLNRIIHLRKGEDKGKTRAQPDLSSALTRL
                     FANSENDDEESSITHITESTSQIWVEDQDPALVDLLATLSFTITTSTSDSSTLLALLAS
                     ALDILSTYAQNHKVNTLPIYTALLRHLDTYTSYLIWDHEILLTDAEIIFTASSIPTPKH
                     RDNIILQLESAYVSNYETCKTLVTRLNQLVDIELMERADWIFPRQIGWVEVRREVIRLE
                     KTLKEIRWAGKLKEVEYVNC"
ORIGIN
        1 atgcatacga tacccatcac cgtttcttta tacgccttcc tagcgacgac ctttctgttc
       61 tcctgctccg cttatgttgc acaggcaccg ctgagcgatg acaagtgcac cgaaacaacg
      121 gtggccatct tgtaggagct tcccactaat gcttgatatc gtgttggagc ttagcgtcta
      181 acgttaacag gggtggaggg atggccggca ttgcagctgc agtaggtgac cctcaggccc
      241 ctttgcccta aatcccgacc ggcaatgctc accaacacgt ctagcaagcc ttgtccaacg
      301 catctatcga cgactttatc atcctcgaat atcgcgatac cctaggtggc cgtgtctggc
      361 atacggactt cggcaaggat aaacaaggca agccatacgt gattgagcta ggagccaact
      421 gggtatgaca atctacatac atcccgtcaa atgaacatcc gcctcaccat aacaacagct
      481 ccaaggactc ggctccgaag ctatcgagaa tccagtctgg gcactagcca aaaaataccg
      541 tctcaaaaac acctactcta actacagctc catccgaaca tacaacgaaa ccggctacac
      601 cgactaccgc tatttgctcg acgaatacgc gcaagcctac cacattgccg cccgcgatgc
      661 tggccgcatt ctgacccaga acctacaaga ccaaaccgca cgcaccgggc tcgccctcgc
      721 cggctggaga ccacgcaaga atgacatggc ggcacaagcc gtggaatggt ggagctgggg
      781 tatgaacaat taccattaag agggggaaca cccaaccctt tttacaccca tcgggtcaac
      841 accaacccta tcccatagcc caccctcgac taacgcatat cccaaaacta gactgggaag
      901 acgcacatac gcccgaaacc agctccttgg tcttcggcat cgccggtgag aacctaacct
      961 tcaaccaatt cggcaaagcc aaccacctcg tcctcgaccc gcgcggctac agcaccatca
     1021 ttcaaaacga agccctcggt ttcctaccca acccctctga tggccgccta cgcctaaaca
     1081 cccgcgtcac tcgcattgaa tactccccaa ggggcgtaac aatccacacc accaacgaca
     1141 acaacaaaaa cagcaacacc tgcatccgag cggcctacgc aatctgcacc ttctccctgg
     1201 gcgtcctcca aaacaaagcc gtaaccttcg acccaccttt gccctcctgg aaacaaaccg
     1261 ccatcgagaa attcaacatg ggcacctaca ccaagatatt catgcaattc cctgagacct
     1321 tttggcccac agacacgcaa tttttcctat acgcttcccc aacaacaaga ggctactacc
     1381 ctgtcttcca atccctctcc acagagaact tcctccctga atcaaacatc ctcttcgcca
     1441 ccgtggtcga cgaacaagcc taccgcgttg aacgccaatc cttgactcaa acgaaggacc
     1501 agatcctcaa tgttctaaga gagatgttcc ctgataaaca catccctgag cctacggcgt
     1561 ttacttaccc ccgctggacg aatgaaccct gggtctacgg cagctactcc aactggccgg
     1621 cgggaacgac ccttgagatg catcagaatc tgcgggcgaa tacgggccgg ctgtggttcg
     1681 caggcgaagc gaccagtgcg gcgtatttcg ggttcttgca tggtgcgtgg tatgaggggc
     1741 gcgatgcggg tgagaatgtt gccgcgctgt tgcaggggag gtgtgttgag gatgttagta
     1801 ctactagtac tgctagtggg aaagaagaga aggaggaagc gtgtggagag agggtctttt
     1861 atgagcaatt aaatgggact acgccgctgg atgcgtatag tcggttgaac gggtggccgg
     1921 cggtaagtta ctactagaag tggtatggct ttgtagggtc tgctttagtt gttggataga
     1981 ttggatggat gaatggcgtt ggcatgggaa attacttttt tggaatttca tattagtctg
     2041 catcatgtaa cgcaataatt tgggattata catcaactgg cctgctggcc caatggtaag
     2101 gcgcttgact acggatcaag agattgcagg ttcgagtcct gcgtaggtca ttctttttgc
     2161 ttttttctta ggtggagagt ggatctggta cggtggggcg ccttccgtac gggtactatc
     2221 gctggaaatt atctactcgt acagtcgcct ttctctgcgc tcaggttttc tttggggggt
     2281 gtggtatgaa tcggcatctt aagtcggttc ctgtcctttg ttatagcata tgcataattc
     2341 tcatcatagt ctcctagcaa ggtgctaccc aatggagttc aatgtcgtat taatcccctc
     2401 aaactactag tatgctatca atagtatata tttcgggcaa ctactacttc attctaggat
     2461 cagtagtagc taccaaccgt ccagcctgaa cgcccttcac cgtctgaagc aataatgttg
     2521 cccaattcgc tattgcatcc atcgctagtt cgtgtttctg ccaatagcta ccttaaacaa
     2581 cctctgaccg tttcttcgtt gcatcattcg ccatctcatt cataaaagca ctccgtgcac
     2641 gtacctcctt cccccagaca aacattaatg taggtataag cgacaacacc aagcaaataa
     2701 aggcaagtag cgtactagcc cactgatatc ctagcacccg gtacatgctc atcgttgcga
     2761 ggggcaagaa agcagagaag acattctctc ccgcagcaac agcacccatg gcacttcctg
     2821 aaaactgact gtaagagtcg accacatagt ctgatactcc agtcacgaca caaacactgc
     2881 cagcacctac caaggccaag ccaacagtag gtgcaatcca tggaagactc gaatatgaag
     2941 tccaagcata gatgaacata ccgcccgaga gaccgagaac ccctcccacc acagccatgt
     3001 atagcctcgc ctctgggatt ggagttcccg gcacctcggt atttctggaa gcagacgcga
     3061 aatagagctt ccgagaaagg aagttcacta gccagcctag acattctccg atgacgatgg
     3121 cgcattgaac ataaccggtt tgtgaaacgt cccagttata taggcccatg aacacctgct
     3181 caacggactg ggtaaagagg aaaagagtcc ccactgtgaa agcggaccaa agggtcgaca
     3241 cgaagagaac cggctccgta gaaaataaaa tcaccggtct tgtcgcgctg actacaagac
     3301 tatgcaggtt caaacgagag gaaacatccc cgctccctgc ataaccgctg gtctcgtcgc
     3361 cattcttgcg attacgtcgt gctcgtcgtg caagaatcgc gctgccacgc gactcatgaa
     3421 ggaagaagta atagattgga aagagagccc cgaaccaaat gagctgcata tagctaatcc
     3481 acctccagcc taaagagtgg aatatcgcgg cgccaatcac ggggcctgta ctgctgccgc
     3541 tcatgtaacc gagaatatat agactgactg ggatggacct ggaccactca gtgctccata
     3601 gatttccgac aacaccggcg gcggtattgg ccaggatagc gacacagccg ccggcgaaaa
     3661 agcgggtgac cactaatgtt gcgaagttat gagcaacggc ttgaggcacc aggaagcaaa
     3721 taaataatag atatgttgtg aggaagatag gcctcgtccc gaaatcctct gctaggggaa
     3781 gaatgaataa agctgagcat gcaccgccgg tagcccatgt tgttaccggc cagtaagaat
     3841 taggaaatgc atcctcgttg acatggaagt gttctgagat ctcgaagtgc gccacagtaa
     3901 tgatggttcc gttcatcatc gccaggaagg tagtgaaagc agcgaggcat gtcagggtcc
     3961 atttccgtcc cactgaccag ttgtaggggt tttcgggatc attatcgtca tcccaagaga
     4021 gagtcgcggt gtcactttca tttgacgcga tatggtcttg gaagacttcg gtcggggttg
     4081 gagaatattt ctctgtgcag gttgccatgt attcgttgtg cttggttctt actgctcacg
     4141 ataattcacg agtgtatgtc aaatagagat agtaatcatc cgccatatgg ctatggaccc
     4201 tactgtatga cctatatatc attgacagca acatatccag ggctttgtga agcgtcttgc
     4261 ttctcacaat agtgcccttt ttgggaatag ttaattgata gttacttata gtcttggctt
     4321 gatgcagcgg agccctatcg ggaaggctga tggatgcaac tttgcggtaa ctcgcttgac
     4381 ttcgggttcg tgagccgatt agccgccgtg aacacagtgg tatcagtcgg caaccttgaa
     4441 ccgagaaaat gaaaacggtc caacaggccc attgtggaca ttgaatgccc tgcattactt
     4501 ggagttactt tgtagaccta gtatgactgt aaagcgtaat aatgatcata attaccatga
     4561 tgcatgtttt ttgtagctat taattacatc cccaagatcc tagtgatacc ggcgatgaga
     4621 aagaacagct gtactatgcg acgatgaagc cacgaacttg caggtaccgg atcacggtct
     4681 ggtagaatgc caggctacaa tgatcattgt cccgatatgc atcggttatg cttgggaatg
     4741 caacttgcgt gactttcctt actaagaatg tgccgaaaag cgactattag cagctgacga
     4801 agatccgact gaagtccagt tcacgagcca atggttcaca cggcgtttta agactagtat
     4861 attgggctaa tcagtctaga acaccatctt acaagtagga atatcggagt gcgtgcaaat
     4921 gcgcgcccgc taatctatga caagaatgag aatctgagcc tcagcagact gagttactgc
     4981 taactcaatt aggtgaacga tcggagaacc agaagaactc tacggatttc gcccgcattg
     5041 ggcttgatga tcttcactgc atatctgcca agtcaatcat tcttcccgag cagcccatgc
     5101 cttcacttcc taatcgagaa cccgacgcct ggaagatccc gagggtatct cggaaaggca
     5161 cccgaaggca tatgtacatt gtaacttagg ccatacccgc ggacaggctg aatccagacc
     5221 acaaaataag ttaaactaac ttcggtttgg cgcatccgcg catcccagag atacagtgaa
     5281 gccgaagacc aactgacagt tgggccgtgg accacgggca accagccacc gcgggactgt
     5341 aattataggc cacggtgttg gacccagaaa taccgttacg gtctttacgg atatcatatt
     5401 caagccggcc cggattcgaa tgagctagtt aatgtattat tcatttcttc ttttccattg
     5461 ataacattct ttccctttct cttgagatgt gctgagtacg aagctgatat gagatgcatc
     5521 tagggcacct gtggccacaa cgagaaggat agtcaagtac aaagatgaca cgacaaactg
     5581 accatactca aggttatcac tacatcgtca ttctttccat gtcccatgtt tcacgaacgt
     5641 catatcccaa tattatatcc caatcagctg ctaacctttt ctgctggctt gcacctggat
     5701 acacgcacca tgagtggtgg cacttcccat gttgtccatg aacgatgacc tgcgagccag
     5761 gggctagatt cattaactgc aagttcacag tcaaactccg ttacaaattt gcagaatact
     5821 atttttgtca tggcatatgc catgctattt tacatatcag ttagacaatt tcatgcataa
     5881 taggtattag gttcacttac tcttgaccaa tacaaccccg cggacctgtg gaaaatggat
     5941 gaaatgccgt tttattatct ttctggtacg ggtcatctgc accatctagc cagcgatcag
     6001 gaataaattt gtcagggctc cagaagtggg tgggggaatg tgtggctgca aaaattggaa
     6061 tatagacccg cgtgtttcct gagacccatc gaccggctat gcgcgccccg cctgcagggg
     6121 tagcacggtg taaagctcca gggaccgagg gatacagcct taaagcctcc ttgatacagg
     6181 catccaagta cgcgagattc gacacagatt ccagagatac ctggctctta tcgtgaaatg
     6241 ctgtgcgaat gtcatttttg agacgcgcaa gacactcagg gtgctgaagg agatatgcag
     6301 ttaaggctgt catgagcgct gtggtcgttt ctgctcctcc agtcatcata atgtgggcgt
     6361 tggcacggat gtctttttca gtcaacgaca agctgcgact gttgcgaaat gcaaggccga
     6421 taaggtctgg ttcgtcgctt tgcaattgaa gccgacggtc tatgaggtca ttcgaaggct
     6481 tgaagtaagc cttgcggagc catttcgaca tccagggtat ggtcgaccgg aataaaaggt
     6541 taatccagga gaattcagcg agagctgata ataaagtcgc ggcacgtacc agcctgtgct
     6601 ggctgtgtac ccacgattta tgtgctcctg ttcgcaagac gcccaattcc tcgccaaagt
     6661 gcaaatgccc aacgatgtca aaaagcgtgt aatggaacat gttgcgtata tttgtgattt
     6721 gcccttctat tccagaaagc ctttcaacga gagcgtcgcc atacttggca aggattgatt
     6781 cctggcgggc taaggctcgc cgtgaaaatg ccggtacgta tgctcgacgg attcttgggt
     6841 ggtctatttc attggccgca agaatagagg gccgattgtc atcatcctca agatatctga
     6901 aaaagtccga ccctctccgc atactctgtg gctcagtggg agaactgcta tatatgtctt
     6961 tccaggcttg tgggtcgata aagctcagct cattcggagc aacacgtagg actggtccat
     7021 atttgagatg aaggttatgg agccactgtg tttgaatccc cttgagtgag gcataagtca
     7081 cgggaatcct gctggcggcc agcattcgcg ggccggggac ctctttcagt ggatgaatga
     7141 acagattata agtaaccatt gataggtact atagatcact ctcggtctta gttctctcaa
     7201 tcactgaagt atcttctgaa gaatagcagc ctttcataac tgaccagaaa aatccctgtt
     7261 gccacaagaa tgcttgccac gttttcttcc ggcatcttgg ctccgaagat atgtcgtgca
     7321 aggccattta aatgtcgacg gggagtgtta tatcaaatag aggaagtgag agaacaatgc
     7381 agagtggtag attgacttgc tcgtagaaaa gttatctcca ccaactattt tcagagtcga
     7441 ataactgcat ctacacgagg catgggaagt catcaaaagt cgatctacaa gtggtaagtt
     7501 tttcaaacag gacgatccag ggtgtgagta ggatgttcct gtgaccttgt gtaaccgacc
     7561 tcattattcc ataaacccct tacatcaacc accgctggaa ccataagagg catacatgat
     7621 tattccatag ccaagggcta tatattagca gaagaaatca ctgtctgctg ggtgagcaat
     7681 aataatggtt cctctatctc atgtcaaagc agccgcctcg ctatagccaa aaattcaaat
     7741 cactcatatc ggttagtatc ttgaagaaaa ccttgacaga agcaatgcac agagatggat
     7801 tatcatagtg cccaaatagg acggatgcag agctgtcaca caatgttcta tacctccttg
     7861 aagcgagcac ctggatttcc cttgctaact cggacagcac gacacttgct attagtcccc
     7921 cggtcatttt caccgtcaaa agatcaatac cctattgatg gtcttgtacg ctaattaggg
     7981 tgtagtagca gaccggttga gatacaaagc acacccatcc agagatcagc ctatactctt
     8041 gcaagcttac aacattcctc gacccacaag cacatcatac gtcgaggatg catatctgca
     8101 aatccccacg gctgaacact tgctgatctc tttcattctg agtagcttgt gcataagcca
     8161 ttaacttgca cttaccgcgc aaacatcatc tcatttgtct ataccattat tcatccatgt
     8221 catctcacac aacatgacca tccttgcatg cagatgtctc atggcaaact cacccatact
     8281 ttttcgtcag tgtgacaaag ctgtgcaaat gcctcttgct ccaatgtcaa cgccagtcat
     8341 atcaacgata tgacgacatt gactttctta tcaaagccac agacaccatt attgtccttg
     8401 agaatgtgcg atgaatccga tatggcaacc taatgacgta gtgaaatgtt ttttttgacg
     8461 aacagctcca actacactca tccgctttaa tagtaccttc ccaataccta gtacatccca
     8521 caacaccata accattagca cggtctgcaa caatgacaaa agcgcaaacc gcagtatcac
     8581 ccgacgaatt cttcaaaatc atcaccccct tcctaaacga aatcattccc aacatcccgc
     8641 ccttcgcgcc cgacgaagca ttctacaaag cagtcttcga caaattcgca gctgcctccg
     8701 gcctcccaga agacagcatc ccccacttcg tcggaacagg cgaagtccta gcacgatgct
     8761 tctaccccag cctaccccga gatctacaaa tatccatagg agtcttaaca gcatacgtct
     8821 tctcaatcga cgatcaatgc gcagaccccg agttccgcga gcagatcaaa tcgtaccgct
     8881 cagtctttct cggccaatct accacgaacc tccagtatat caagggtcta tacaataccc
     8941 ttcacgatat agtcagtcac tatgagtggt atgctggtga catgatcatc aaatcaacca
     9001 tggacttcgt gagtatcaat attgtggagg cggagcagac tggtgatttc atggtctctc
     9061 catctaccaa gttgtttccg gacttcttgc gacagaaaag tggtatcggt gaggcttatg
     9121 cgttttttta tttccctggg agtgattggg gtctggggga ttattttacg ttgatccccg
     9181 atatagcggg tattattgag cagttgaatg atgtgctgtc gttttataag gagtctgttc
     9241 taggaaatga gcccggaacg tgggttaagc agacttgtgt ctgtaagggg atttctgaag
     9301 gtgaggcttt cagggagaga gtggatcagt gcttaggcag tattcggaga ctgcgtgctg
     9361 catctgaggg aaatccgaga ctgctaaaga cagtcaatga gttcattaat gggtatcctc
     9421 tcttccatct taacgcgggt aggtataagc tggatcagtt tggcagttat catggttggc
     9481 agggtgagaa gacggcgggt gggaattgat agtataacag gccaacgcag ctggaaggga
     9541 ttggaataag attgaactcg ggtcaaagca tttaagacta agaatatact ggtgtcaaca
     9601 acgtgaagag ggacgttcat tgcaatttgg gggccatcac gattctatat actaaggcgg
     9661 agcgagagtg acagggccgc gttgctcaaa ctttcacagc acaatactag gatacctttc
     9721 acaagactca aagagaggac agtcctttga tttcattact gatcacgagg tgtacgcaag
     9781 tgtcacactt cctccaaaaa gtattcgctt atttccaagc cgagtcctaa attaggtggg
     9841 aaaaaggacc ctatgatctg ccctgtgctt ggatcataag gaaggctctc atcgtaagta
     9901 tcctgagcgg tggtatcctt gtccgtatgc atgaggtcgg gactttctga agcaggctgg
     9961 ccttttaaat gggcttccag agaagttgac ggatctgaga gcggtagagg accacatcca
    10021 agttcattag tctgcggctc tggagcagac gaaagtccgg ttggtccagg tccaggcgta
    10081 acagaagtgc cgaatctgct agggatgggc gggttgggta aattcacgcc cgcatattgt
    10141 tcgatacggc gcaaaagacc ttcgcatagt aagcgagctt tctccgaggc cgcgttggta
    10201 tttgcgagta tagcaagcca tttaagtgct ctttcggtcg ccttagaaac catcgatgct
    10261 ttctctggta cgtggcaaac accaaaagac agttccatta aaaggaccgt ggttgcttgt
    10321 acaagaaaat gcagtataca ccaccaaggt gacattctgt acagcgcagc agcatctagc
    10381 ccatctggga acaatctcag catatggcaa gctgattcca cgcactcagc tgctgttctc
    10441 tgacagaaat cctgtatctt ttcatctgga gttttgccat cctgattcac aggattggga
    10501 cggcgcagac atggccgtgt tattccaatt ttggtgctat agaatataaa tgccaggctc
    10561 attcggtggt tagatatcga atgagtaacc tgcgtggatt gggtcgaggt aaagtcaaac
    10621 tcattaggaa ggctcagaag ccatgattcg atgtcagatg taagaccttg tatggcgaat
    10681 tctatcccca tccaagacgt gctcgctgct gagggactgt aaagcttagt tatcatcttc
    10741 tttgatatca gcatgagccg aatgacatgg aagaagtgca acgatccaga gggaggaccg
    10801 gaaattgcgc ctgtaccctt ggagattgct attgagtgtt tgcccatcaa atcaaaatct
    10861 gtatgaattc cttcagttcc gtgtgagaac cggaggcaat ttataacttc atccttcccg
    10921 aaatcctttt cgtcaaatgg tactggcaga ggtgttgtat agacagtatc atctatgaag
    10981 gaaggccgtc ccgtgattat gctaagtcgg tgatcaagcg tgtagagaga ccaccataca
    11041 cgatatcgaa tctccctgga agtatccgaa gcagacttgc tcatgttgcg cagatgcaac
    11101 ccaagaccaa gggctccccg aacagcactt ccacagattc tccaggcact tggtatattc
    11161 gtaagcactc acatgaatag ccgattcgta cctcccgaca tgatatacgt accggttgac
    11221 atgccccaat gaaagcatgt ataaagctgt tagcccttcc acttgtaatt gctgtaggtc
    11281 aggatgatga aagctccaat catctatact caagaccctc gctcttgaga aatacaacca
    11341 gtgattattc ttgttcagct gccattctgc ttcagagatg taagcatacc tagcagcaat
    11401 cgcaaataat aggttcaaga ctgcgagcca cttgttaccc gtatgtaacc tggtatcgtt
    11461 gaagaatgcg tggaactgtt ttccaaaagg tgtggttcct atgattggga aggtaggatg
    11521 cacccaatcc aaatagcagt tgtagagctt tgaagctaca tcctttgatg gtagtgcata
    11581 tgcctcttgt cgctcgatat ttggcagttc ttgatcatca acatggtaat tcgatgcgga
    11641 gataggacta ctatcagaga tcgataaaaa tatagcttcg ctcggagtac cgtgctcagt
    11701 gtctccattg atatctcggc ctaatgagtg tatccatgat atttcggagc tttgaccaat
    11761 ataaccagta gcttgggaaa tttcgtcctt gttgaagtct tcattgatgc aatcaaggca
    11821 gtggcttgag tcaacatata gtgacaactg ggaactggta gctgagagag gtctttgagt
    11881 tccgggcaag ggggttcgcc catcggggga caaggaagga ctagaggact cttcctactt
    11941 ccggtcagta taaacactcg aagagagagg acgaagagga tataacgggc tcaagaggat
    12001 caaaggatat ggtttcaacg agagcaaggc gaggggcctg tattcatacc acagtcaatg
    12061 caaggttcat cagctgctca ttcgtaatcc caaatctgct gctcaggttc ttcaaagcat
    12121 cttcgtaagt ccgtattttg gcctccaagc tagccaattg ccttggcgta ccaatttctc
    12181 tgaagtcagc cacggagcca tctaatcaga ttcagactca cctcttggat ttctcccttt
    12241 taccatctgt atagcagcaa atgatgccag cctcacggca gttgcgacaa ccggacttat
    12301 ctccagtgca ctttgtcttt ctctgtctgc aggattcaca tgctcggctc acgtggcgac
    12361 gatgaaatct acctggagtt gagaatgttt ccagcccttc tgctagccta ggaattgcca
    12421 tcttcttgct agtcaaagga tgctccgctc tgtgggagga caatgcatga gatgcactac
    12481 ccttgagatc ctcagttaac tttcggactg gtagatagac gagaggggga tcggatggcc
    12541 ctcaccacat cgctgtagtt gtgcgaaccg gtcgaggata tcctgaaggt cggttgttct
    12601 ggccaagatg gatactgcat tgtgctatga aggtctaagg aagaaagtcc acaattctgt
    12661 ccaagcaatc attagtagct gttctgtagc agcgccttag agagctcatc ttgatgtcac
    12721 ccatcactga taccttagag agttgaacaa ttgcaggatg atacaccaga gtaattgaga
    12781 ggatgtcgat aacgtttaca gaaaaggtag ctgagctgaa tcttaatata taattttaag
    12841 actgagttct tcaacgaaag tatagggatg taactcagcc cgaaagagag tgaaactagc
    12901 tttgaaagag taacgtctca cggttcatca aaaatcgaac cctcgatcag tttcttcccc
    12961 ccaacaagat ttcttttggt gaaaagtgca ggcggaaagc gcagtcgtgg ctacttccct
    13021 tgtgtctctt gtttccctcc agccgaggat cggcccgtct ctgagtctag atgctaggta
    13081 ccaaattatc aaccagaaaa gcgagaactc taggagacca ggtattaggg agaccagaat
    13141 tgccgctgat ttccatggat atgaaatggt agagtgctac cagctccgga aaatgcaggg
    13201 aatgtagacg gattattcac catgattagc cagccgctca ctgagtaccg tttgcttcaa
    13261 gcgtaaccgc aacattttct ttgactggct agacggcagt gttatgagag agggttgagg
    13321 gcttgacaca aggttaaatc tggaccagtt catcgttgta tttaggcagg atatggagta
    13381 cgtgatgggc ccacgaggat acttccatca tcttcgttgg ggccaagcta aacaatgtgc
    13441 tcatagtgat tagctccttt gggcgaacca cggtcgacat cagcagagtc tgtactgcat
    13501 gtaacgttct cagagtttct ccgtcatgtg cctgccagcc tagcggaaat cctggataat
    13561 ggcccagagg attaaacttt gccctgcgca actaatacgc atacagaata aattttccac
    13621 tccatgaaga atatttaggt gcctattcgg acccgaccag ccgaatatat ccctgtatcc
    13681 gggtcaccct cttcgtagtc ggttatttgc agcggcttaa ggtgatagtt tactgatcca
    13741 agaacattcg cgtgtacacc atcaaaatat ctgttatttc tagaaaaaac tgacactacc
    13801 attcgaaaac agattgatga taagtgagtc aaaaatcaat aaataaaaaa aaaacacaaa
    13861 gctttgttat catgaatcgt acatataatg tggcccgatg gctttgtttt aacatgcgta
    13921 gtggatgata actattactc gagcagatga attatagttc aaagtacgta ttgagtgaaa
    13981 catagattct tttcaaatta acagacaata gatgaaatga tctttagaat tccttacaat
    14041 tgtccactgg atggacgaga ctggagttgc agaatgcggt agcgggccag gacaacagac
    14101 actgccataa gcccctccca ggcagatata ttgagtatcg tgttagtcat agtctaatgt
    14161 attcaggacg aaggtgcacc atctgtgata ctgtgacaag cgatttcacc atagcatcct
    14221 gatcgattca cggagtagcc tgatagtcca tctccgtagc ctttcagcca taaggaaatt
    14281 tcatcggctg tgtgcaaact tgagcaggag atttataggg ataatatggt cctacgttac
    14341 actcctaact taaaatcgaa tcactcatta gttgatcggt accctccaca tttaccttgt
    14401 caattgccac agtatcatgc cactttccgt gtcgaatatg ttacctaaag ccttaggcct
    14461 gatccacggt acaagggctg gactagaggc tcatgttctg cagcctgatt acacataacg
    14521 agaataatga aataagtttg tagttttatt atctccagat tggaccccca ccattttact
    14581 cttaaccaat gcatcggtga tatccaccga acagaattac atctgaagtg atactgatga
    14641 agaaagctgg cccagacagg cgttgattgc tttggccagg ttgtggtttc gtgaagcagg
    14701 aattagtggt ggtggtggag gacatagagc aggcgttgtc ctgtatacca atttcgcaaa
    14761 ccggtgcaaa ttctcaggaa tcggtcatat tggactgtgg ggaatatgaa tgactttgac
    14821 tgctgtaata gacgccttga ggctcgatga ggcagtctgg ttgctggaag tgatataaac
    14881 agagaataag gctacagtga agaaccatgc agccttggct ttgcccgtta aattatcttg
    14941 agtcacagaa ctcgcacatt ttctttcacg gcacgtcccg ctttcacgct gcttggttgt
    15001 gtgtgctaca ataggtatat aaatccctgc ttccctcgct tttctctgtc tatccaatct
    15061 tccttctcat cacatctgaa gttctgcagc ctcttagtca ccgaaacgca tgttacgtat
    15121 ttgatcccta cagtccgata ggttataata aagcgaccta tatacccgtt gatgtctcta
    15181 ccacattgtg tacaatggaa agtggtgtac ccccaaagct tcatgactct cacgacacat
    15241 cgaaatgctc tacgtatcac tttggatatg agactataac tgacccatgc tgaacatata
    15301 cggcagatcc tcctctggcc cgaagaatgg gattccatga cgctatgcct cgtacgaaga
    15361 gagccatcgg cgcatccacc gcaagctgag ggacagatga actagaaacc ttaagagcat
    15421 acataagaga ttctcctcag gctcagcgat atcaatgagt tctgagcttt ggaatgattg
    15481 agtcacttct tggggttgcg ttcggcacgt atatataatc ggaactggat tataggtagt
    15541 acctaattca cgacgtcatg gaaattcacg cggctgttct tcagttgagg atgactggct
    15601 gttgcatatg agcgtgggta aaggagcatt ctccacctcg ctgaagacag ctttagaact
    15661 cgcgaagctc ctatgcgcaa tcatgaccac ttgggcattc gagattttta agtgttgccc
    15721 tcatctcagt gttggcagac taagctacgg tccgctgctc ttgaggacgc aggagcatct
    15781 tgtgcgctgc gaatctgtac tttccatcgg gatcccttcc gggggtgtca tggtagttta
    15841 atgcgacaga gcttgccaga caaccgaaat ccatgaatgc agtctcaata tgcacacttc
    15901 aacatttcac gctcgcacaa atgcttttac gagccatggc tgctacaagt attgaaagat
    15961 acatcaaaaa ggaaaagcac aacgacttcc tcacaattca gagattgagg attttcgtgt
    16021 acccagcacg gagcaagcat gccataccgg ctgatcactc ccatgcccac gacagctatg
    16081 gactgcacgc cagtctgagt actgctggtg tcttcgccga tagaaaagac aaataaacag
    16141 cgaatcgcaa ggcaacgaag gatatgtctc acgggttctc tgagaaatga tagtctcatc
    16201 acgcaattac gtctccacca gtcccgaagc ccaggtccac cggcgcctgc ggatggaagt
    16261 agcatacaaa catctctaga ccttttcatt atcatgaatc gattcttaat attgtactgt
    16321 gaaagctgca tggttagctc atttcaacag tgcagtctct atcaggttgt atagtgtgaa
    16381 ctgggctgat gggattgaag aacatgaata aattctgaac ttgggcgagc tatcggctca
    16441 ttcccatttg tttagctttg cgttattgta tatgttttct ttggcgggtt taagcttatt
    16501 aacgatattc ttctccttcc gatggtgaag gacctgatgg ctaacacctg tgtaacagaa
    16561 ataatgagct ggaagactac gaatttcatt gggtaagttt tggagctttt cttcatctcg
    16621 aagattgcct ctctattaac aacttgtagc aaccggaaat ggcactgtga tatggcctcc
    16681 ttccctacgg agatatgcgt atgttcaata ccgaaggttg cttcaccgac gcaatgatat
    16741 cagactagcc ttcgacatag gaggatgact gctatgggca ttcaatgtcg atttcctact
    16801 gttgttagtc tatctccaag cgtagctttt gctatgacaa aactggacta gtatacagtt
    16861 aaaggttgac ttctgtgtct tctatacctg tcattgacag acccattcag ctatccggca
    16921 caactagaag gagcgtaaaa gccaagtaaa acgatattta ggaaatgggc gagtacgtcc
    16981 tagtaattta ggggaataaa atccagaaac atccacatcg ggcattacat agaaactgca
    17041 gggtgtgatt caacgcgatg taaccacaag catgcaggct gcatcaatat tgtgatctgc
    17101 gggatagaga tcttccgata tcaatgaaag gtccgacaga gcgtcgtgaa gaccttcgta
    17161 ctgctattgg agattatgga tcctgacctc ttcgacggag taggcaaagg taatatagga
    17221 ttccatccaa gaagagcaca acaggagccg tcttggaatg ccaagccagt cgcaagattt
    17281 aatggctatg gcatgtcaac gccattagcc atccccttcc atagaataaa accgcgaaag
    17341 atgcaatctt cattctggta gcttccggca acataaagac gaagcgagcg atctcaggag
    17401 aagcattcca gctttgtaca tttgctgttg ccaaattttg tggcctaatt aaccaaatga
    17461 cttctatttc tgctggtgac gataccacta cgctgcttcc tggcaggaac cgaagtgacc
    17521 agtatagcct gcgaagtcaa tatgtcatca atttctatat taagcctatg tgaatcaaag
    17581 tgacccatgg atgggaagaa aaatccgagt tcaagaacta tatcgtctat tcttagtttc
    17641 taatgttctg attgctgagt atctcttcta caaccctcaa cattatattc aagttttatc
    17701 atttgaacac tcctacccta ttatctacca gtttactagc aagcttccta cctttggaaa
    17761 ctccgctgga gaccatacca tcgctaccaa aattccgccc gaaacatctc agacaccgac
    17821 ttccctcaaa agctcctctg cataggcgac tctattcacc ctctgccctg tcaaccaaat
    17881 cttcagtacc catcttaacc atctataaga tggctcctat cctcctctcc aacaatatcc
    17941 gtactccctt cagatacttg aatcgcatca tccaccttcg caagggcgag gacaagggca
    18001 aaaccagagc ccagcccgat ctatcatcag ccctaacccg actcttcgcc aactctgaga
    18061 atgacgatga ggaatcgtct atcacccaca tcacggagtc tacttcccag atatgggtcg
    18121 aagaccaaga tccagccctc gttgacttac tcgccacact ctcctttacc ataacgacca
    18181 gcacatccga cagctctacg cttcttgcac ttcttgcttc tgccctcgac atcctatcca
    18241 cctacgctca aaatcacaaa gtcaatactc ttccaatcta taccgccctc ttgcgtcatc
    18301 tagacaccta taccagctat ctcatctggg atcatgagat ccttcttaca gatgcagaaa
    18361 ttatctttac cgcctccagt attccaaccc ctaaacaccg ggacaacatc atcctccagc
    18421 tggaatccgc atatgtctcg aactacgaga cgtgcaagac gctagtaact cgtcttaatc
    18481 aactagttga tatagagctg atggaacgtg cggattggat atttcctcgc caaattggct
    18541 gggtagaagt aaggagagaa gttataaggc ttgaaaagac tctgaaagaa atcagatggg
    18601 ctggcaagtt gaaagaagtt gaatacgtca attgctaa
//
