LOCUS       ch8                    22325 bp    DNA     linear   PLN 04-MAY-2020
DEFINITION  Aspergillus niger strain KJC3.
ACCESSION   ch8
VERSION     ch8
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Circumdati.
COMMENT     'Annotated using 1.7.1'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-03 01:23:18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4803564
            Orig. end    :: 4825889
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22325
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[4813564:4813973](+),
                     [4814042:4814274](+), [4814343:4815889](+)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(10001..10409,10479..10710,10780..12325)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..22325
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22325
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="10"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            join(433..5410,5469..5957,6025..6140,6193..6627)
                     /locus_tag="KJC3_012868"
                     /product="hypothetical protein"
     gene            433..6627
                     /locus_tag="KJC3_012868"
     CDS             join(433..5410,5469..5957,6025..6140,6193..6627)
                     /NRPS_PKS="Domain: SAT (150-381). E-value: 6.6e-13. Score:
                     40.4. Matches aSDomain: nrpspksdomains_KJC3_012868_SAT.1"
                     /NRPS_PKS="Domain: PKS_AT (1621-1816). E-value: 1.6e-21.
                     Score: 68.6. Matches aSDomain:
                     nrpspksdomains_KJC3_012868_PKS_AT.1"
                     /NRPS_PKS="type: PKS/NRPS-like protein"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 29.8; E-value: 4.4e-09)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="KJC3_012868"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KJC3_012868-T1"
                     /sec_met_domain="PKS_AT (E-value: 5.5e-20, bitscore: 68.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTATTELHPNPSPSPSGDGPSVAFTLEHGEATAALSVSSAVATTL
                     QPYRASWLADDTISPLSLTLSFLGHLTRQKAPLSAVQTAVRAFETQYLAGIDIHTAVTI
                     LPDALGAKKTALRDYYAAAAYTGQPLSNSPSALFKSAQTGTSRITTIFGGQGTANPSCV
                     RDLRSLYTTYRPILTQLMQECGPVLSSLSQRPDTQSYFRGRSIDLNSWLAGATTLNEDF
                     VSAAPVSLPILGLFDLAHYCVISSVLGQTPGQVATSMHAISGHSQGIVVAAAVARADSW
                     TSFYDNARLAVELLFWIGFESHQDAPHLFIAPELVEQTKEQGHGVPSPMLSVRGLERPA
                     LEKLLAQCNQVLPESRQLHIALINARTNHIVAGPAASLCGLSHVLAELQAAGEKDQTRI
                     PFSQRKPAVTHSFLPISTPFHTPYLQAASQRIKERLADRAFSADQLQVPVLHTATGEDL
                     RVNPQSNVIEALVDAITTEPVDFPGLLADATTTHFLVLGAGRLSELVKQIRQGYGQQII
                     AASELKPSSADIGSQADLFAPTLRPAPSSWADAYQPRLVQTANGRLILDTKLSRLLQVP
                     PIITAGMTPTTVPWDFVAAVINAGYFIELAGGGYHTEDEMRVAIEKIAAAIPPGRGITC
                     NLIYVNPKAIAWQTRLIRKLIRQGVPIDGLTIGAGVPSLEVAREYIDDLGIKHISFKPG
                     SVDAINAVLQIADDRPDFPIGLQWTGGRGGGHHSYEDFHAPILATYAEIRKRDNICLVA
                     GSGFGAGDDTYPYLTGQWSVARGYPAMPFDGILLGSRMMLCREAHTSPAVKQLLATTPG
                     VPDGEWEKSYKGSAGGIITVRSEMGQPIHKVATRGVRLWADFDQTLFRHPRPKMVEELA
                     KRKTEIIARLNKDYAKPWFGQDARGQPIDLADMTYAGVLARMVELMYVAHQQRWIHPSY
                     QRLVSDVAVRTLERVAPSVELSLDLLDAPASFLQVLSEKCPAAATQRLHPDDAAFFLRR
                     CQARGQKPVNFIPILDENFETWFKKDSLWQSEDLEAVVGQDPERVCILHGPVAVRYATD
                     KDESAQEILDGIATSHTHAALQDFYRGDLQRVPKVVNASAATSHTQPESSYEVSSLDLV
                     TDSSFSWVRDLLETPTIIREGIRKKNTFRSILAVKPGQKLVVNHTQQRIVLCESSTEQP
                     VISIQSDGTRTISVDLHQPSSFTAAPAVLSLQYKARSAGLSPALEEVVDGRNDRIKTFY
                     RNLWLGEAADPTKDSHSTFHGPEITLTRDLLEDMYRTLGLSPTGIRPESLPMDIAIVIA
                     WEPLVEPLVCAGVEGDLLRLVHRSNDIDYVPSATPFQVGDVLRSSSQIQSITIEPTGKS
                     IVVKATIERAGEPIAFVTSTFFMRGTYTDYASCFERITEPETMLEVSTPVDEELLRSRP
                     WLQLDEPTTPLVGKTLCFRLETSIDWKDQTTFQTLQTSGTVSLRSWNGKQTPIGRVSFE
                     ARDGKANPVSDFLRRRGQPLVARKPLEVTQELNQTSEGVQIPASNAGYSTFSKDFNPIH
                     ISSEFAQYVELPGTITHGMYTSAVVRAVTERCAAQGDLTRFRRWACSFVGMVLPSDQLE
                     VRVQHVAMIEGRLLLNVTAIKAGTDEAVIQAEAEVDQPSTVYVFTGQGSQSPGMGMSLY
                     KSSAAARAIWDAADKFFIETYGWSVLELVRQNPTALTVHFRGKRGRQIKANYMAMTIDA
                     YRADGTLVKEPILPELTPKSTSYTFADPRGLVFSTQFAQPLVLLLERAAVEDLRQRGVV
                     QGDAAFAGHSLGEYGALASFGEFMPFTDLLRVVFYRGLAMQVAIERDDQGRTNFSMAAV
                     NPARVGKFFTEKALRQIVTQIATTTHALLEIVNFNVDGEQYVCAGTLENLHALAAITDT
                     IARSPTGAALAREFTDATTIGNADLASTKLVEQCIAEARQLPAPVSLKRSLATIPLQGI
                     DVPFHSAHLRPGVASYRNFLEERIPKTEVDPQKLVGKWIPNVMGTPFSLSREYVEGVYG
                     LTQSPILKEVLAR"
     aSDomain        883..1575
                     /aSDomain="SAT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KJC3_012868_SAT.1"
                     /evalue="6.60E-13"
                     /label="KJC3_012868_SAT.1"
                     /locus_tag="KJC3_012868"
                     /score="40.4"
                     /tool="antismash"
                     /translation="IFGGQGTANPSCVRDLRSLYTTYRPILTQLMQECGPVLSSLSQRP
                     DTQSYFRGRSIDLNSWLAGATTLNEDFVSAAPVSLPILGLFDLAHYCVISSVLGQTPGQ
                     VATSMHAISGHSQGIVVAAAVARADSWTSFYDNARLAVELLFWIGFESHQDAPHLFIAP
                     ELVEQTKEQGHGVPSPMLSVRGLERPALEKLLAQCNQVLPESRQLHIALINARTNHIVA
                     GPAASLCGLS"
     CDS_motif       886..927
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KJC3_012868_0001"
                     /evalue="9.80E+00"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="KJC3_012868"
                     /score="0.2"
                     /tool="antismash"
                     /translation="FGGQGTANPSCVRDL"
     CDS_motif       1210..1266
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KJC3_012868_0002"
                     /evalue="1.70E-03"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="KJC3_012868"
                     /score="11.3"
                     /tool="antismash"
                     /translation="HAISGHSQGIVVAAAVARAD"
     CDS_motif       5290..5346
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KJC3_012868_0003"
                     /evalue="1.60E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="KJC3_012868"
                     /score="17.3"
                     /tool="antismash"
                     /translation="VYVFTGQGSQSPGMGMSLYK"
     aSDomain        join(5296..5410,5469..5938)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KJC3_012868_PKS_AT.1"
                     /evalue="1.60E-21"
                     /label="KJC3_012868_PKS_AT.1"
                     /locus_tag="KJC3_012868"
                     /score="68.6"
                     /specificity="Minowa: trans-1,2-CPDA"
                     /specificity="PKS signature: (unknown)"
                     /specificity="consensus: pk"
                     /tool="antismash"
                     /translation="VFTGQGSQSPGMGMSLYKSSAAARAIWDAADKFFIETYGWSVLEL
                     VRQNPTALTVHFRGKRGRQIKANYMAMTIDAYRADGTLVKEPILPELTPKSTSYTFADP
                     RGLVFSTQFAQPLVLLLERAAVEDLRQRGVVQGDAAFAGHSLGEYGALASFGEFMPFTD
                     LLRVVFYRGLAMQVAIERDDQGRTNFSMAAVNP"
     CDS_motif       5771..5881
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_KJC3_012868_0004"
                     /evalue="7.20E-06"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="KJC3_012868"
                     /score="17.9"
                     /tool="antismash"
                     /translation="AFAGHSLGEYGALASFGEFMPFTDLLRVVFYRGLAMQV"
     tRNA            7377..7447
                     /locus_tag="KJC3_012869"
                     /product="tRNA-Gly"
     gene            7377..7447
                     /locus_tag="KJC3_012869"
     mRNA            join(10001..10409,10479..10710,10780..12325)
                     /locus_tag="KJC3_012870"
                     /product="hypothetical protein"
     gene            10001..12325
                     /locus_tag="KJC3_012870"
     CDS             join(10001..10409,10479..10710,10780..12325)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Terpene_synth_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 125.8; E-value:
                     3e-38)"
                     /gene_kind="biosynthetic"
                     /locus_tag="KJC3_012870"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KJC3_012870-T1"
                     /sec_met_domain="Terpene_synth_C (E-value: 2.8e-06,
                     bitscore: 23.7, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MFKQYSHILSHKRRRSRGSTINQVLSGAQSEPASEAATVSEPVEV
                     WTHSQVLPEDDEHRKDCFTTLTPRIHKYDHVAQRGSDRFVQDLTAALNLDEPQTSYLSS
                     PVGNYASFLYPECLPERLETVAYLTELGNLHDGKQQGKKTDESAESPRVAARKQLLEKA
                     MSELSDKDKDGHEIIDCYRSNWLVTPEVPTAENCANLDDYVARRRLNAGIDVYWTLMGF
                     AHGTRLGKEDQAVVRDALDAAERTMFFTNDYYSWPKEKRVSKKKPVANVILFLMEHQNM
                     SEEDAVAKAKQLIIDNEHEFVRRREALYQANSDLAPQLRKWMEVLGASLAGIHYWCKNA
                     PRYAVPETAEESEEEESSEEDGSDEEESSSDEDTDDDDEEEEEEEEEKAAPVEVVPEPE
                     ESEEPVEVAVWTPLVTEEETPDVHLDTSALLAPSSYARSISRSTLHSDLLTSLNAWLQV
                     PARPLAFIRQVITELQDSTGMLADVQDQAALRDQRTPAHLVYGPAQCMNSAAYLFVRAA
                     RIVTSLNCPGMLDGLLQELEAHFVGQSWELNWRFSTHCPGETEYLAMVDQKAGASFRLL
                     TRLMQAASMGGATLDLEPFTKVLGRLSQIRHEYLGLLESAASDRSFGEDLDQAKVTYPI
                     VRACNLDPAGRAVIFGIFRQKPAGTVLPIESKRQIVSLVQQTGALQATYDLIRQLGREA
                     MNTLSELETAAEELNPSLRAVVKSLVEVPAPDHL"
     mRNA            complement(join(12606..13741,13804..14137))
                     /locus_tag="KJC3_012871"
                     /product="hypothetical protein"
     gene            complement(12606..14137)
                     /locus_tag="KJC3_012871"
     CDS             complement(join(12606..13741,13804..14137))
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 449.9; E-value:
                     1.4e-136)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="KJC3_012871"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KJC3_012871-T1"
                     /transl_table=1
                     /translation="MSQSIPQHPGQRENIETRLFINGEFVPSLSGSKFDLYNPATEELS
                     ASVYEAGPEDVDRAVAAAKAAFPAWSETGALQRAQLLEKWADRLEACADEMAYLDAICM
                     GKPAYSDNVGRIMPLFVRVYAAKALDITGESSLNTPGFVNVSLRQPFGVCGAIVPWNGP
                     VVTMIFKAAAALVTGNTIVIKSSEKAPLSCLVAARCAQEAGIPPGVFNMLSGFGRPCGE
                     AIARHMEIRKISFTGSTATGRAIQKMAAESNLKSVTLELGGKSPLVIWDDADMSKAVPA
                     AAMSILTNSGQVCVASSRVYVHEAIAPQFLEQLKTTMTEMGKSGHPLIPGTTRGPQADA
                     AQFARVQGYLDLAKQEGVSVYLGGEREGDKGYFVQPTILKDVPEESRLMKEEIFGPVVA
                     VNTFTDEEDVMARANDSEYGLYASIYTRDISRALRAAKKFEAGTVGVNCTSPTMAFDMP
                     FGGWKGSGEGRELSRYATDYWTELKSVLIAL"
     mRNA            15397..17205
                     /locus_tag="KJC3_012872"
                     /product="hypothetical protein"
     gene            15397..17205
                     /locus_tag="KJC3_012872"
     CDS             15397..17205
                     /codon_start=1
                     /locus_tag="KJC3_012872"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KJC3_012872-T1"
                     /transl_table=1
                     /translation="MTGSLPSVLQTLLADSHYFSLQRSVCHHNHHRQHDIASIESMDSW
                     AQFRLMKQLLCVRHPRQSLPSSLLREIDQVLLEERANRLLLDAASIPALPTPSSSSKPL
                     PATLHLWQGDITTLDGVTAITNAANEQMLGCFQPAHRCLDNVIHARAGPRLREECFHHM
                     DQGQRTLPVGHACATKGYCLPAPYVIHTVGPQLDAGQPVPTAHQRQQLRQCYEAVLDVA
                     EALPASDPRGKSIALCGISTGLFAFPVEEAASIAIQSVLDWLRHHLHTSITNIIFNTFT
                     DTDTAVYQQTLKKMHYPVPSLVPPPRVHGSSLIQAKAWLAAADTILISCGAGISAATGL
                     DYTSTTLFDRHFPAFKQYQLRRLYDTFGRTNRDWPSESVRWGFYFSHLAMVRRWPRSSL
                     YTSLLKWLASRFQPDRVHVRTSNADGLFAAHGLPEAQLSTPQGQYAFLQCLENCRPDAV
                     FPSAPYLDAALPHLDPQTQVVTAQDKIPTCSFCGGAMSICVRAGDWFNERPFAPGETRW
                     HQFREAFLTDLTRNVVIIELGVGLSTPGVLRWENEELIEQGDGRVRLVRAGLGDAVQVP
                     GELAAAQLATSIEGDLQDVVRAIVAP"
     mRNA            join(17813..17872,17933..19592,19649..19926)
                     /locus_tag="KJC3_012873"
                     /product="hypothetical protein"
     gene            17813..19926
                     /locus_tag="KJC3_012873"
     CDS             join(17813..17872,17933..19592,19649..19926)
                     /codon_start=1
                     /locus_tag="KJC3_012873"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KJC3_012873-T1"
                     /transl_table=1
                     /translation="MPRYNWWYSPLVLGVIYSALVPSLVTADSLHNVHLDFLDSSFEGH
                     INLFYGDCHTGQGHHEIGHIVIERDAHPERFVWITPADAPHLHCLHAISGSTLLARSDP
                     IPIATRLARRESIADVADVMGPWFDGVAYMQGKEPGKAVVSAAKNSSVAIIGGGISGMM
                     TSLLLNSVGMTNWHIVESSHRLGGRIRTHYLNDSRPDQYQYQELGAMRLPMNITYADTN
                     ETLQIQDMRLVLQLADVLNELNADADPALRVNFIPFIQDNPNLPTDTGGVRLPDGRIPT
                     VAQVAANSSLAYTAPPDNASAVADAKAQYMQYAQTDKMGKIREVARNMYRAHKAALEDG
                     FYHWSEAAYMRYALGENADVVDYAAGTANNPIWDGFYDSVYFAATTWFTIDQGMESLVR
                     AFLPHVADKATLGRKVDGLSYNESSGKIAYTWRDSPVQITPERSEEYDYAVVAAPFTKV
                     RMWELPRYSSILSRAISETNYEPACKLALLYKTRFWEHQEQPIFGGCGTVDIPGVQYVC
                     YPSFNLNGTGPAAVLGAYSHGSPARSVQALKLEDWVALARRSMVEIHGAIAEEQFTGIS
                     HGHCWENDEHQNGAWTHPLVGQQEIFLPAYYQTEFQTIFVGEHTTYTHGWIAAALDSAV
                     RGTTQLLLDLGLVDEAKAIVHEWMGRWIEL"
     mRNA            complement(join(20368..20427,20488..21558,21606..21775,
                     21826..21960,22012..22180))
                     /locus_tag="KJC3_012874"
                     /product="hypothetical protein"
     gene            complement(20368..22180)
                     /locus_tag="KJC3_012874"
     CDS             complement(join(20368..20427,20488..21558,21606..21775,
                     21826..21960,22012..22180))
                     /codon_start=1
                     /locus_tag="KJC3_012874"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KJC3_012874-T1"
                     /transl_table=1
                     /translation="MADKKIDVDCIEHVDQVLVDEAGRIQRLPVPSDDPNDPLNFALWE
                     KTGIVVCCCWFSIMSLSVIGGLGSVLDVFFQMYGAEGHSTNQVVWLSTFPSLFVGIGNY
                     IILPLALVCGRRPVMLIANTVLLGSLIGCALSQNWAQHFGLRILLGFATGATESLLPLM
                     LAEVTFIHQRGTIYGIYWATQNIVTSLLTLASSYEVAALGWRWFYWVFVITVAVGLVLV
                     VFACFETRFQRRPIFVGDHAVVTDQYGVTRVLTATETQEYLTSEEGRSYADLDGDTPPK
                     KTYRQMLSAWPRLCPHPLRDVLLTWWQMLETFSSPGIIYATLLSAVILGGSVGVSLTYD
                     TVLQYNYGWGAASIGLINLGGVFGGLGGMLYAGILGDRVIVWLARRAGGVHKPEHHLLL
                     LIFPGLLAVASLLLYGFTASGDATWGGPFMGWTLYQVAFVSTLIRTTSFATEAWEKNPG
                     PALVTVVGTKNIIGFGVSYGLNPMVAKYSYPAAMGILAGVVGGVLLLGVPVYFYNPMWR
                     RYISQQRTRDRGQSGGP"
ORIGIN
        1 tagggcttgc gcgagttgtc gtcggcggca ggaatgacag tcatgctgga cggggcaatg
       61 attggaggat aagagaacgc actagatctt ctctctcctc ttcctttcaa tgaggaatca
      121 tttgttgcct ttcaagtact ttatgaaatg ttgcattcag ggcagtggcg ggccggatct
      181 tgcatcctgg cgtggttcgg gtttcggccg ccggatgaga ctctgcagca acaccgaatc
      241 aattgctgag agatgctttt gctgccgaac agctttcaat cggcaggatt tggtctgtct
      301 gactcagcta tcgaagcaat gtgagacaac gaagtcagtc ttataatcga cctcaaaagc
      361 tatctatctc tggcctcttc ttcttgccca ggttgttgtt atcccgacca aatgtcgccc
      421 tagtcaccca ccatgactgc gacaaccgag cttcatccca acccttcacc ctcgccttct
      481 ggggatgggc catccgtggc ttttaccctc gagcatggcg aggccactgc cgcgctgtct
      541 gtgagtagtg ctgtggccac cacactgcag ccctaccgcg ccagctggct ggccgacgac
      601 accatctctc ccctcagtct aacgctgtcc ttcctcggcc atttgacccg ccaaaaagcc
      661 cctctatcgg cagtccagac cgctgtgagg gcctttgaaa cacagtatct cgcaggcatt
      721 gacatccaca cggctgtcac tatcctgcca gacgcccttg gtgccaaaaa gactgccctg
      781 cgggattact atgccgccgc agcctatacc ggtcagccct tatccaactc acccagtgcc
      841 ttgttcaaat ccgcccagac aggcacctca cgcatcacaa caatctttgg cggccaagga
      901 acggccaatc catcgtgtgt gcgcgattta cggtctctct ataccaccta ccgccccata
      961 ctcactcagc ttatgcaaga atgtggccct gtcctgtcct ctctgtccca gcgcccggac
     1021 acacagtcct actttcgcgg tcgttctatc gacttgaatt cctggctggc cggcgcaaca
     1081 accctcaatg aggactttgt cagcgccgcg cctgtcagcc tgcccattct aggactcttc
     1141 gacctggccc actactgcgt catctccagt gttttgggtc agacccccgg gcaagtggct
     1201 acttcgatgc atgccatctc tggccattcc cagggcattg ttgttgccgc tgctgtggct
     1261 cgtgccgact cgtggacatc gttctacgac aacgcccggc tggctgtcga gctgctgttc
     1321 tggattggct ttgagagcca ccaagatgcg cctcacttgt tcatcgcgcc cgagcttgtt
     1381 gagcaaacca aggaacaagg gcatggagtt ccttcgccaa tgctttccgt tcgaggactt
     1441 gagcggccag cactggaaaa gcttctcgcc cagtgtaatc aggttctccc tgagtcgcgc
     1501 cagctgcata tcgccctcat taatgcccgc acaaaccaca tcgtcgcagg tcctgcagcg
     1561 tcactgtgcg gtctcagtca tgttctcgcc gagctgcaag ccgctgggga gaaggatcag
     1621 actcgcatcc ccttcagcca acgcaagccc gccgtcaccc actccttcct ccccatcagc
     1681 actcctttcc atacccccta cctgcaggca gcgtcccagc gcattaagga gcggcttgcc
     1741 gatcgcgcgt tttccgcaga ccagctacaa gttcctgttt tgcacaccgc gacgggtgaa
     1801 gatctacgag tcaaccctca gtccaatgtc attgaagccc tcgtggatgc catcaccacc
     1861 gagcccgttg acttccccgg tctgttggcc gacgcaacca ccacccactt tctcgttctc
     1921 ggggctggtc gcctcagcga gctagtcaag caaattagac aggggtatgg ccagcagatc
     1981 atcgccgcca gcgagctcaa gccttccagt gccgacatcg gtagccaggc cgacctcttt
     2041 gcaccaaccc tccgcccggc tccttcatcc tgggcggacg cctatcaacc tcgcctggtg
     2101 caaacggcca acggccggtt gatcctcgat acgaaactca gtcgcctgct gcaggtaccc
     2161 ccgatcatca ccgccggtat gacgcccact accgtgccct gggacttcgt ggcagctgtc
     2221 atcaacgctg gttactttat cgagctggcc ggcggaggct accacaccga agacgagatg
     2281 cgggtcgcca tcgagaagat cgctgccgcc attcctcctg gccgcggcat tacctgcaat
     2341 ctcatctacg tcaatcccaa ggcaatcgcc tggcagacac ggctgatccg caagctcatc
     2401 cgccaaggag tacccattga cgggcttact atcggtgccg gtgtgccgtc gctcgaggtt
     2461 gctcgcgagt acatcgacga ccttggcatc aagcacatct ccttcaagcc tggatcggtc
     2521 gatgccatca acgctgtgct gcagatcgct gatgaccgac ccgacttccc catcggactc
     2581 cagtggaccg gtggccgggg aggcggccat cactcgtatg aggacttcca cgcgcccatc
     2641 ctggccacct acgcggaaat tcgcaagcgt gacaacatct gcctcgttgc cggcagtgga
     2701 tttggtgctg gagatgatac ctacccttac ctgaccggcc agtggtcagt tgctcggggc
     2761 taccccgcca tgccgtttga cggtattttg ttgggcagcc gcatgatgct ttgtcgcgaa
     2821 gcccacacca gtccagcagt aaagcagctg ctcgccacca cacccggtgt tcctgatggc
     2881 gagtgggaga agagctacaa aggcagcgcg ggtggcatca ttacagttcg gtcggaaatg
     2941 ggccagccta tccacaaggt ggccacgcga ggagtccggc tgtgggccga ctttgaccag
     3001 acgctgttcc gccaccctcg tccgaagatg gtggaggagc tggccaagcg caagactgaa
     3061 atcattgccc ggctgaacaa ggattatgcc aaaccctggt ttggtcagga tgcccgtgga
     3121 cagccgattg acctggcaga catgacttat gctggagtgc tggcccgcat ggttgagctg
     3181 atgtatgtgg cccatcagca gcgctggatc catccgtcat accagcgcct ggtgtcagat
     3241 gtggccgtac gcaccctcga acgcgtcgct ccgtccgtgg aactgagcct tgatctgctg
     3301 gatgcaccag ctagtttcct gcaggtgctg tccgagaagt gtccagctgc tgccacgcaa
     3361 cgcctgcatc ccgacgatgc ggctttcttc ctgcggcgct gccaggcgcg tggccagaag
     3421 cctgtcaatt tcattccgat tctggacgag aacttcgaaa catggttcaa gaaggattcg
     3481 ttgtggcagt cagaggacct ggaggccgtc gtagggcagg atcctgagcg cgtgtgcatc
     3541 ttgcatggcc ctgttgccgt ccgctatgcc accgacaagg acgagtcagc ccaggagatc
     3601 ctcgacggca ttgcgacctc gcatacccac gcggcactgc aggactttta ccggggtgat
     3661 ctccaacgag tgcctaaagt cgttaatgca tctgccgcca cctcccatac ccagcccgaa
     3721 tcttcgtatg aagtgagctc cctggatctg gtgacagaca gctcttttag ctgggtacgt
     3781 gaccttctcg agacgcctac tatcatccgc gaaggcatcc gcaagaagaa cacattccgc
     3841 agcatcctgg ctgtaaagcc aggtcagaag ctggtcgtca atcacacgca gcagcgcatc
     3901 gtcctctgtg aaagcagcac ggaacagcca gtgatcagca tacaaagcga tggtaccagg
     3961 accatttctg tggaccttca tcagcccagc agctttaccg ctgcccctgc agtcctctca
     4021 ctccagtaca aggctcgttc cgctggactc tctccagcgc tggaggaggt tgtagacgga
     4081 cgcaatgacc gcatcaagac cttctaccgc aacctttggc tgggagaggc ggcagaccct
     4141 accaaggata gccactccac cttccacgga cctgagataa ccctcactcg cgacctgctc
     4201 gaggacatgt accggacttt gggtctttcg ccgacgggca tccgaccgga atctctgccc
     4261 atggacatcg ccattgtgat cgcctgggaa ccgctggtcg agccgcttgt ctgcgcggga
     4321 gttgaagggg atctgctgcg actcgtgcac cgctccaacg acattgacta tgtgccctcc
     4381 gctacacctt tccaggtcgg agatgtcctg cgctcgagta gccagatcca gtccatcacc
     4441 attgagccga caggcaagtc gatcgttgtg aaggccacca ttgagcgggc cggagaaccc
     4501 atcgccttcg tcacctccac cttctttatg cgcggcacat acaccgacta tgcctcctgc
     4561 tttgaacgca tcaccgaacc ggagaccatg ctcgaggtct ctactcccgt agatgaggag
     4621 ctgctgcgat cccgaccgtg gcttcagttg gatgaaccca cgaccccgct cgtcggcaag
     4681 acgctctgct tccgactgga gacatccatc gactggaagg atcaaacgac cttccagaca
     4741 cttcaaacga gcggtactgt ctccctccgc tcctggaacg gcaagcaaac gcccatcggt
     4801 cgggtctcct tcgaagctcg cgacggcaag gccaatccgg tgtcggactt cctacgtcga
     4861 cgcgggcagc cactggtcgc tcgcaagccg ctcgaagtca ctcaagagct gaaccagacc
     4921 tcggagggcg tgcagattcc cgcatccaac gcgggctata gtaccttctc caaggacttc
     4981 aatcccattc acatctcgtc tgagtttgca cagtatgttg agttgcctgg cactatcact
     5041 catggcatgt acacgtcggc tgtggtacgc gcagtcactg agcgctgtgc ggcgcagggt
     5101 gatctgacac gtttccgccg ctgggcctgc tcgtttgtcg gcatggtgct gccgagcgat
     5161 cagctggaag tgcgcgtaca gcacgtcgct atgatcgagg gacgattgct gctgaatgtg
     5221 acggccatca aggctgggac ggatgaagcg gtcatccagg cggaggccga ggtggatcag
     5281 ccctcgacgg tgtatgtctt taccggacaa ggcagccagt cgccaggcat ggggatgagc
     5341 ctgtacaagt ccagtgcggc tgcccgggcc atctgggacg cagcggacaa gttcttcatt
     5401 gagacctacg gtatgtaata ccccttgttt ttctgtatcc cctctagcaa gctaataatg
     5461 gcattcagga tggtcggttc tcgagctcgt ccgccagaat ccaacagctt tgacggtgca
     5521 cttccggggc aaacgcgggc gtcagatcaa ggccaactat atggccatga ctatcgatgc
     5581 atacagggcc gatggaacgt tggtgaagga gcccattctt ccggaactca cgcccaagtc
     5641 cacttcatac acatttgccg acccgcgcgg tttggtgttc tcgacgcagt ttgcacagcc
     5701 tctggtcttg ttgttggagc gcgcggcggt cgaggatctc cgccagcggg gagtagttca
     5761 gggggatgct gcgtttgcag gacactcact gggcgaatat ggagcattgg catcgtttgg
     5821 cgagtttatg cccttcacgg atctcctgcg agtggtgttc tatcggggtt tggccatgca
     5881 ggtggccatt gagcgcgatg atcagggacg gacgaacttt tccatggcgg cggtgaatcc
     5941 ggctcgtgtg ggcaagtgtg agtaaccatt gatactctcc tgtgtggatg tggggtttac
     6001 cgtgaatgct gacatggggt ttagtcttca cggagaaggc attgcggcag attgtgacac
     6061 agatcgctac gacaacgcac gccctgctcg agattgtcaa cttcaatgtc gatggcgagc
     6121 aatatgtgtg tgctggaacg gtgagttctc tttcccccac aacgaggtat gttctttcgc
     6181 tcatgatatc agctcgagaa cctccatgcc ctggccgcca tcaccgacac tattgcgcgg
     6241 tctcctactg gggctgctct cgcacgcgaa tttaccgacg ctaccacgat cggtaatgca
     6301 gaccttgcat cgacgaagct ggtagagcaa tgcattgcgg aagcacgcca gctccccgcg
     6361 ccagtgagct tgaagcgcag cctcgcgaca attcccctgc agggcatcga cgtgcccttc
     6421 cactcggcac atctgcgacc gggagtggca tcgtatcgca acttcttgga ggaacgtatc
     6481 cccaagactg aggtggatcc gcagaagctg gtgggcaagt ggattcccaa tgtaatgggg
     6541 acgccgttct cgcttagtcg ggagtatgtc gagggggtgt atgggctgac gcagagtccg
     6601 atcttgaagg aggtgctagc acgatagaga agagtagggt tgtgctgtgg gcctttatgt
     6661 gtatatgata gactgtctga cgattcgtct gtgtttcttg ttaccttgta gtagttggtt
     6721 gctgtctact tctacccttt tggaatacat ttaccaatca cttcaattat cacagtacag
     6781 tagaataaca ttcccgcgct agctgctctc gatataaaga tactactcga gtatgcttga
     6841 ccgggtcttt gggttttgta gacatgttcg tgtctttatg accctcgtcc ccggtggtcg
     6901 cgttgtgcat caatcttgga tccctttctc ttttctacgc gcctctactg tgtctttata
     6961 ttcttggtgc tcggtcggtt gtttattgca agagataaga aaggaagtgg aattatatga
     7021 aatactattc cagttaagtt caaactagtt cacttgcaaa caaccatagc agcagtacta
     7081 gtaggtgttt cctagtactc cattatatat tttggggcaa ctcaggtata gtactcgtat
     7141 tacgtgttat gttttttaaa gtaggccaaa cagcgtgtgc atggaagaac tcagtggctc
     7201 cttgcatctt aatcggacgg gcttgaaaag agatagggct tcaataccat atgttcaatt
     7261 gttggactta tggaggtact acacgctggg ctcttcattc agagggtcta cttggagatt
     7321 gactgtaagt gtgtcaacta cttgtaacac aagtattcac tccataatat ataccagcat
     7381 cattggtcta gtggtagaat tcatcgttgc catcgatgag gcccgtgttc gattcacgga
     7441 tgatgcactc ttcttttttc ctctttcctc tttttccccc ccgctcttcc ttcccagcca
     7501 tgtctattcg ttcattctac tatctatttt tgctatctcg tatctcctct cctctgtctg
     7561 ctgtcaatcc acctccaatc atcgccagcc ctcagactgc cgccctgcag ctctcgggcc
     7621 tgccgatcgc aacccaccgc tgcagttccc ccactccacg gctcatcttt agcagaagtt
     7681 tagacctgcc tatctgtcta ctttgtgtct tttggatggc tgtctggttc aacggttatc
     7741 cacagttgat caagtgactc tgttgccagt ggaacagcta ccctgcacct aactcttttc
     7801 tctctcttca gccacttgcc agccaacggg gtcccttctg cctctgatat tggaggatga
     7861 cgctatccat ctcgcacttc tctcgctggg tttcgctggc agcttcacat tggcccgttg
     7921 aggttgacat gactaactac ggttcaaagt agtgcaaagg ctatcttctt agcttaggat
     7981 ggatgctcag aacgaatcat cgggccggga ttcgctggtg atcgggggtc agccgagggg
     8041 aggaatgacg agcttccctg gaagtgccat catcaacctt ggtgggaggg gcaaaccaga
     8101 ggaggaaacg acaaacgagt aaggcaaagc aaaggcaatg caatgcaatg cgagaaccaa
     8161 agcacagtca gtggattcca ccttcacaga gggagaaaga gaacaaaact caccagagta
     8221 aggcaatgat ccgcaaacca aggtccaatg ggaaacccga cggagaatta acaacgcccg
     8281 gttccaccgt aaagatgtca ggttgattgc cttggagggg gaccctctct cgtctcctct
     8341 ctgtatctcc cagaacttgt tggaattacc cactgtggaa aaagtgatgc tatctcggga
     8401 caatgaggac cctcctggcc cgagcgtttg cagcctgcag agattgtcgc tgggatcgct
     8461 ggcagaaact ctacttctct cctacaataa ctttttcttc ttttatcttt tcaatcatct
     8521 tggaggggaa actaaactta aacatgggaa tagactttgg attgatgccc agccacatta
     8581 ctactcaagt ttatgtagcc gagaaaatca taatgtgact ggggatggga ggctaacgag
     8641 agagatcgca ccatctgcac tcatggtatg actgaaccct ctccaagcga tggtaacgag
     8701 ggcaaccaca accgcccatt tgaacagtga ctgtgccagt gtcagtgccc tccagagtct
     8761 ttaccgcgat cgcgatggcg tcgattccaa ccaaattgtt atgctttctc cctctcgggc
     8821 aggtggggcc gttgcgtaac tcggaattct gattgcatcg cgaaaccgaa aatattcccc
     8881 aagcaaaagg tgtgagtgag tgatggatcg atggcagtgg aagtgtaaaa agtagtgact
     8941 atcaagaagt tgtcgatcct gcggagtcta tctcctctcc cagactactt tgtgtactcc
     9001 gtactacttt ttttttttac tacgtatact tcctagtgct gcctgccata tcaacccctc
     9061 cctccgatca tcatcctttt tctgactaga tactgtagac ttgttgactg cctaatcaac
     9121 tgaaaacgag ctaactactc ggtagtctgc cttgatagtc tttcgtagtc ttctgcacca
     9181 ctccgatctc tgctcgccag ccaccgggac aggcgatatt tgcaaggcaa tttggcccct
     9241 ctacgaacct actttcgccc gacaagttga acatgaaaaa tcgaaagcaa aaaatattcg
     9301 cccccgcggc ggacagatga attctttcgc accttcggag acaaaacatc gtcatatctg
     9361 ctggtggaca tgcgttggcc caatgagaag gacagccagc agcgcgtcga ggatgaagcg
     9421 gtgaagggca cagcgatgga gatccacatc gggcaagccg tggaggtgaa gctaaaaacc
     9481 ctaacggcac taagaagacg cagaatgatc agaatcctcc atcccagcag ctaatggacc
     9541 cacgaactgc tgtagccgca agacagctgc cgttgtgtcg ccaatcagcg agctttcggc
     9601 cgcgtagctt gcatcccgtc cactcggcag cttctcaact cctccctctt cgtttgcttt
     9661 ttttcgctgc tactcactgc ttctcgggga ccaactggag gtccatgctg ttttcccttt
     9721 cgataaggat gtgaaaattt ttcttgttgg tcagaccatg acgccgacac caatctggag
     9781 gggtggacat ctttgcgcat gagccagcga tctcaaattg ctattaaaga ctccatctgg
     9841 ttcctcttct gctccctctt tctctcttcc ctttcttcct tttcaactta tccgcgtcga
     9901 tcgcgttgtg aaatattttt atattgtgac cgcattgctg gtcctgtatc actactctta
     9961 ttaccttttt ctttcaattg ttctgttgtg aatcatccca atgttcaagc agtactccca
    10021 catcctgtcc cacaagaggc gtcgcagcag gggaagcacc atcaaccaag tcctgtcggg
    10081 cgctcagtcg gagcctgcat ccgaagcagc cactgtcagc gagcccgtcg aagtatggac
    10141 gcactcgcag gtgctgcccg aggatgatga gcatcgcaag gactgcttca ccaccctgac
    10201 cccgcgcatt cacaagtacg accatgtcgc ccagcgcggc agcgatcgct tcgtccagga
    10261 cctgacggca gcgctgaacc tggatgagcc ccagaccagc tacctttcct cccccgtcgg
    10321 caactatgcc agcttcctct acccagagtg tctgcccgaa cgtcttgaga ctgtcgctta
    10381 tttgacggaa ctgggcaatc tgcatgatgg tatgtgaaac cccattaatt accatcacca
    10441 tctcctggca tggctcggac ccaccactga cgtcttaggc aaacaacaag gcaagaaaac
    10501 cgatgaatcc gccgaatccc cccgtgtcgc tgcccggaag caactgctgg aaaaggccat
    10561 gtcggagctg tcggacaagg acaaggatgg ccacgagatc atcgactgct accgcagtaa
    10621 ctggctggtc accccggagg tccccacggc cgagaactgc gccaacctcg acgactatgt
    10681 cgcccggaga cgcctcaatg cgggcattga gtaagtcacc ttcacctccc ccccttgcat
    10741 agccatacat atacaatgga ttgctaacgt ggataccagc gtctactgga ccctcatggg
    10801 cttcgcgcac ggcactcgtc tcggaaaaga ggaccaggcg gtggtgcgcg acgcactgga
    10861 tgccgccgag cgcaccatgt tcttcaccaa cgactactac agctggccca aggagaagcg
    10921 cgtctccaag aagaagcccg tcgccaacgt gattctcttc ctcatggaac accagaacat
    10981 gtccgaggag gatgccgtcg ccaaggcgaa gcagctgatc atcgacaacg agcacgagtt
    11041 tgtccgccgt cgcgaggcgc tctaccaggc caactcggac ctggcaccac agctccgcaa
    11101 atggatggag gtgctgggcg cctccctggc tggtattcac tactggtgta agaatgctcc
    11161 gcgctatgcg gtccccgaaa ccgcagagga gagtgaagag gaggagtcgt ccgaggaaga
    11221 tggctctgat gaggaagaat cttcctctga cgaagacacc gacgacgacg acgaggaaga
    11281 ggaagaggaa gaggaagaaa aggctgcacc cgttgaggtg gtgccggaac ccgaggagag
    11341 tgaggaaccc gtggaggtgg ctgtctggac tcccctggtc accgaggagg aaacccccga
    11401 cgtgcatctg gatacctccg ccctgctggc ccccagcagc tacgcccgct cgatttcccg
    11461 cagcaccctg cacagtgatc tgctcacatc tctgaatgcc tggctgcagg tccccgcccg
    11521 cccgctggcc ttcattcgcc aggttatcac cgagctgcag gactcgaccg gcatgctggc
    11581 cgacgtgcag gaccaagccg cgctgcgcga ccagcgcacc ccggcccacc tggtgtacgg
    11641 acccgcacag tgcatgaaca gtgcggcgta cctgtttgtg cgcgccgccc gcattgtcac
    11701 cagcctcaac tgccccggca tgctggacgg gctgctgcag gaactggagg cgcactttgt
    11761 cggccagtcg tgggagctga actggcgctt ctcgacccac tgccccggcg agaccgagta
    11821 tctggccatg gtggaccaga aggccggcgc cagcttccgt ctgctgacgc gcctcatgca
    11881 ggcggccagc atgggcggcg cgaccctgga cttggagcct ttcaccaagg tgctgggtcg
    11941 cttgtcgcag atccgccacg agtacctggg tctgctggag tccgcggcca gcgaccgctc
    12001 gttcggcgag gacctggatc aggccaaggt gacgtacccc atcgtgcggg cctgcaacct
    12061 ggaccctgct ggccgggcgg tcatctttgg catcttccgc cagaagccgg cgggcacggt
    12121 cctccccatc gagagtaagc gccagatcgt gtcgctggtg caacagaccg gggcgctgca
    12181 ggccacctac gacctgatcc ggcagctggg ccgcgaggcc atgaacacgc tgagcgagct
    12241 ggagacggcg gcggaggagc tgaacccgtc gttgcgcgcg gtggtgaagt ctctggttga
    12301 ggtgccggcc ccggatcacc tgtaaaaaaa tttgatacct ttgacggaga cgatgcatgg
    12361 tggttgatac gatgatgatg acgatgatga ggatgacact ccttgtttct ctaatgtcta
    12421 catgtctatt ttcctttggc gtttttctgt gatgatgatt tacgagactt tccttgatgt
    12481 acggctatga gatgatatga ttaatgacga ttatattcaa gtattcgaac gactgccttg
    12541 tgtaaacatg tagaaagaag agtcttattc tcagtacaca gtattatcgc tacaaacatc
    12601 atgaattaca acgcaatcaa caccgacttc agctcggtcc agtagtctgt ggcatatcga
    12661 ctcagctctc gtccctctcc actgcccttc cagcccccaa atggcatgtc aaacgccatg
    12721 gttggactgg tgcagttgac tcccacggtg ccggcctcga acttcttggc tgcccgcagc
    12781 gcccgcgaga tatcccgcgt gtatatactg gcatacagcc cgtactcgct gtcgttggcg
    12841 cgtgccatca cgtcttcctc gtcggtgaag gtgttgacgg ccaccacggg accgaaaatc
    12901 tcctccttca tcaagcgcga ctcctccggc acatctttca ggatggtcgg ctgcacaaag
    12961 taccctttgt cgccctcgcg ctcaccgccc aagtacaccg agacaccttc ttgcttcgcc
    13021 aggtccaggt agccctgcac gcgcgcaaac tgggcggcat cggcctgcgg gccgcgcgtg
    13081 gtacccggga tgagagggtg gccactcttg cccatctccg tcatggtggt cttgagctgc
    13141 tcgaggaact gaggggcaat agcctcgtgc acgtagaccc gcgagctggc aacgcagacc
    13201 tggccggaat tggtgaggat ggacatggcg gcggccggca cggccttgct catatcggca
    13261 tcatcccaga tcaccagcgg ggacttgccg cccagctcga gggtgacgct cttgaggttc
    13321 gattcggcag ccatcttctg gatggcgcga cccgtggcgg tcgagccggt gaaggagatc
    13381 ttgcggatct ccatgtgacg ggcaatggcc tcgccgcaag ggcgaccaaa gccgctaagc
    13441 atgttgaaga cgcccggggg gatgcctgct tcctgagcac agcgagcagc caccaggcaa
    13501 ctcagagggg ccttttcgga ggacttgatg acgatggtgt tgccggtgac taaggccgcg
    13561 gcagccttaa agatcatggt cacgacgggg ccattccagg ggacaatggc accacaaacg
    13621 ccaaagggtt ggcgcaagct gacattgacg aagccgggag tattcaagga ggattcgcca
    13681 gtgatatcaa gggccttggc agcatagacc ctcacgaaga ggggcatgat gcggccgacg
    13741 tctgggtttt ggtcatgagt tagacatgtc tgtctgatag gaatgacgag ggaatgagct
    13801 tactgtcact gtaagcgggt ttgcccatgc aaatggcatc aaggtaggcc atctcatcgg
    13861 cgcatgcctc cagacgatcg gcccatttct ccagtaactg ggcccgctgc agggctcccg
    13921 tttccgacca ggctgggaag gcggctttgg cggctgcaac ggcgcgatca acatcctcgg
    13981 gaccggcttc gtagaccgag gcactcagct cctcggtggc agggttgtac agatcaaact
    14041 tggaccccga gagggagggg acaaactcgc cgttgatgaa gaggcgagtc tcaatgttct
    14101 cccgctggcc gggatgttgg gggatggatt gagacatgat gataacaact caataaagtg
    14161 aatgaagagg aaatagatgt gagtattgac aggtaggaga gcaagagggc catgatgacc
    14221 gggttaatat acgaaaatta aaggatatta ggccaaccgc agcaatgagg ggttatgatg
    14281 gctcggcctc tgcactaatg cactggtgta accgattcct cctatgagag tcccaaagca
    14341 aattcgtatc cctgaaagat cgtcatccgt ggctccatga tcgaggagct ctgacattcc
    14401 agatgttttt ggatgctgtc atgggatgag agttgcttgc cgttctttga gacagctcga
    14461 caggggagag agcctgctgc tgactgccgt ggagtcacta gtcactagct attccgcatg
    14521 cgggatagag tttcaagcac acgaagatct cgcccccaag ctactaatag ctactatggt
    14581 acattatgct gacggtctgg atgtatggcc tggctcgtct caagtggggc gctgagagct
    14641 gaagtatgaa gtgagttgtt cgatggaaat gatatattag taactactaa tagccatccc
    14701 ttgatgtggg actgagacgc agactatatt gcgatgtcct tcattgttca gagggagcac
    14761 aaaagtcctg gatggttgca caattcagtc ggtatgattg cctcctggca tgagtggttg
    14821 aatgattcct tgcgacagcg tcatcaccat ggttgttgaa tgtcatcctg tcatcccctc
    14881 gagtggcgga gatagggacg gatatcggag ttatcgtatc cggggatgat ggtggttgtc
    14941 tcgacctgtt ccatcaggct ataatattgg tagtaagatg aagatgatga ggtgtaaatg
    15001 ctgcagtcag aaaaaaagga atgtgactag ccatctttgt ttctttatgc cagcattgcc
    15061 gatgattctg gttatataat tatgttggcc tgtccatcac ggcggaattt ccccccgagt
    15121 ggataacacc ttcccattcc ggaaatatgt cccgtctaga caaacagtgc aaatgtaaca
    15181 tacagtggtt ccacaaaaat acatggtatt tgcattatgg acaaacagaa caagccagat
    15241 aaacccgctc aatgccaata ataactatgg aacgatcgaa ggggaatcga tgagggaaag
    15301 agagctacaa aagaccccca atatccccct gaataaagat gggaacttct ttcgagatgt
    15361 atcttccact aaaattgtca aacatctctg tcagtcatga ctggctcact accgtcagtc
    15421 ctgcagacct tactggctga ttcccactac ttctccctgc agagatccgt ctgccaccat
    15481 aaccaccacc gccagcatga catcgcctcc atcgaatcca tggattcatg ggcccagttc
    15541 cgtctcatga agcagctgct ctgtgtcagg catcctcgcc agtctcttcc atcctcctta
    15601 ctccgggaga ttgatcaggt gttgcttgag gaacgtgcca atcgccttct tcttgacgct
    15661 gcttccattc cagctcttcc aactccatca tcatcatcaa agcctctccc cgccacgctc
    15721 catctgtggc aaggagacat taccacgttg gatggcgtta ctgccatcac caatgcggcc
    15781 aacgagcaga tgctgggatg tttccagccg gcccatcgat gcctggacaa tgtcatccat
    15841 gcccgggcag gtccccgctt gcgcgaagaa tgtttccacc acatggatca gggacagcgc
    15901 accttgcccg tcggccacgc atgtgccacc aaaggatact gtcttcctgc cccctatgtg
    15961 attcacaccg taggccctca gctggacgcg ggacagcctg tgcccaccgc gcaccaacgt
    16021 caacagctgc ggcaatgcta tgaggccgtc ctggatgtcg cagaagctct gcctgcatcg
    16081 gatcctcggg gcaagtccat tgctctttgt ggcatctcga ccggactgtt tgcctttccc
    16141 gtggaggagg ctgcatccat tgccattcaa tccgttctcg actggctgcg gcaccatctg
    16201 cacacctcca tcaccaacat catcttcaac accttcaccg acaccgacac ggccgtctac
    16261 caacagacac tcaaaaaaat gcactatcca gttccttccc tagtgccacc tccccgggtc
    16321 catggatcct cccttatcca agccaaagct tggctggctg ctgccgatac cattttgatc
    16381 agctgcggag ccgggatctc ggcggccact ggactcgact atacctcgac cactctgttc
    16441 gatcgccact tcccggcatt caagcaatac cagctgcgac ggctgtatga tacctttggc
    16501 cgcaccaacc gtgactggcc atctgagagc gtccgctggg gattttactt ctcccatctg
    16561 gccatggtgc gtcgctggcc ccgctcgtcc ctctatacct cgctgctaaa atggctggca
    16621 tcacgttttc aaccggatcg ggttcacgtg cggacctcca atgcagacgg actctttgca
    16681 gctcatggac tgcccgaagc gcagctctcc acaccccagg gccagtatgc cttccttcaa
    16741 tgtctggaaa actgccgtcc ggatgctgtc ttcccatcgg caccgtatct tgacgctgcc
    16801 ctgccgcatc tggatccaca gacacaggtc gtaacggcgc aggacaaaat cccaacatgt
    16861 tcattctgtg gtggcgccat gtcgatctgt gttcgggcgg gagactggtt caacgaacga
    16921 cccttcgctc ccggcgaaac gcgatggcac caattccgcg aggcctttct cacggatctg
    16981 acacgaaacg tagttattat tgagctgggt gtcggccttt ccacgccagg ggtgctgcgg
    17041 tgggagaatg aggagctgat cgagcagggc gatggacgcg tacggctggt gcgcgcgggt
    17101 ttgggcgatg ccgtgcaggt ccctggggag ctggctgctg cgcagctggc caccagcatc
    17161 gaaggggact tgcaggatgt ggttcgggcg atagtggctc cgtagactgg ccaagtgaca
    17221 tgtagatgtg atacatctaa tttgctaaag cgattctttg ctggactttg ctgtttcttc
    17281 ctgacatggt ctatatattt ctccgggtac ggtagtccat cagctacaca tgcgtataac
    17341 taccaaagca gttttctgtc ctgcgcgatg gccttccatc gaatggaatt gtgaccattc
    17401 cgtgaaatag ccaggaggat gtgatccaag tcgggttagt cccgtcgttc tctccgcacc
    17461 aggcaatgtg gctgtcgaag atcggctttt ggcgcaaatt tccgagcggc aattattgaa
    17521 actagttcgg cgggtcacca ccaagtttgg ccttcagaaa tagacacgca aatggcagcg
    17581 tgtcagactg caataaatca acggcaccca taaacccctg tatctgcagg atcctcaatt
    17641 attgatatct tcttatgtag acacacatca tgtagggtaa ttgaaagact gagttagtga
    17701 tgagaactcg gtggtaatct ggaatggcgc cggtataaaa tcatgcatgg catccgtaca
    17761 atcacccccg tcatccgggc agagtgtgct gacctcaata cctcggcgcg ccatgcctcg
    17821 ctacaactgg tggtattctc cgcttgtcct gggcgtgata tatagcgcct tggtaggcgc
    17881 agtttcccaa catcccccca gagaggttca cagacatgtc ctgaattttc aggtgccgag
    17941 cctggtcacc gcagactccc tgcacaacgt tcatctggac tttctggaca gtagctttga
    18001 aggtcatatc aatctgttct acggggactg ccataccggc caggggcatc atgagatcgg
    18061 ccacattgtc atcgagcgtg acgctcatcc agagcgcttc gtctggatca cacccgccga
    18121 tgcgcctcat ctgcactgcc tccacgccat ttctggatcg actctgctcg ctcgttccga
    18181 tcccattcca attgccaccc gcttggctcg tcgggaaagc atcgccgacg tggctgatgt
    18241 gatgggcccc tggtttgacg gcgtcgcgta catgcaaggc aaggaacccg gaaaggctgt
    18301 ggtgtcggca gcaaagaact cttccgtggc tattatcggc ggtggcatct ccggaatgat
    18361 gacaagtctg ctgctcaact ctgtcggcat gaccaattgg cacattgtgg agtcatccca
    18421 tcgactaggt ggccgcattc gcactcacta tctgaacgat tcgcggcccg atcagtacca
    18481 ataccaggag ttgggggcta tgcgccttcc catgaacatc acctacgccg ataccaacga
    18541 gacactccag atccaggaca tgcgactagt ccttcagttg gccgatgtcc tcaatgagct
    18601 caacgccgac gctgatccag cgctgcgagt caacttcatt cctttcatcc aggataatcc
    18661 gaatcttccg actgacacgg gaggtgttcg tctgccagac ggccgaatcc ctactgtagc
    18721 ccaggttgcc gccaactcgt cgctggcata cacggcgcct cccgacaacg ccagtgccgt
    18781 tgcggacgcc aaagctcagt acatgcagta cgcccagaca gacaagatgg gtaagatccg
    18841 ggaggttgct cgcaacatgt accgcgcaca caaagcggct ctggaagacg ggttctacca
    18901 ctggtcggaa gccgcatata tgcggtacgc gctgggggag aacgcagatg tcgtcgacta
    18961 cgccgctggc acggccaaca atcccatttg ggatggattc tacgatagtg tctactttgc
    19021 ggccaccacc tggtttacca tcgaccaggg gatggagtct ctggtgcgag cattcctacc
    19081 gcacgtcgca gacaaagcca ccctcgggcg gaaagtggac gggctctcgt acaacgagag
    19141 ttcgggcaag attgcctaca cctggcgcga ctctccggtc caaatcaccc ccgagcgcag
    19201 cgaagaatat gactatgctg tcgtggccgc gcctttcacc aaggtgcgca tgtgggaatt
    19261 gccgcgatat tcgtcgatcc tgagccgggc catctccgag acaaactatg aacccgcctg
    19321 taagctcgcc ctgctgtata aaacccgctt ctgggagcac caggaacagc ccatcttcgg
    19381 gggctgcggc actgtggaca ttccgggggt gcaatatgta tgctatccat cgttcaatct
    19441 gaatggtacc ggcccggcgg cggttcttgg ggcatattcc catggaagcc cggcgcggag
    19501 tgtacaggcg ttgaaactcg aggattgggt cgcattggca cggcgcagca tggtggagat
    19561 tcacggggcg attgcagagg aacaattcac aggtaggccg gatcctttga ataagtagcc
    19621 ctcagtctca tgcttactgt cccgataggt atctcccatg gtcactgctg ggagaatgat
    19681 gaacaccaaa acggcgcctg gacacacccc cttgttgggc agcaagagat tttcctgccc
    19741 gcctactacc aaaccgagtt ccagaccatt ttcgttggcg agcataccac gtatacccat
    19801 ggctggatcg ccgcggctct agactccgcc gtgcgcggga ctacccaact cttgctggac
    19861 ctggggctgg tggatgaggc caaggcgatt gtgcatgagt ggatgggtcg atggattgaa
    19921 ttgtaagata taccggagct cagaagtgta caatctcaaa atacaataga ttttttcgtt
    19981 cacacttcca ggtaatttag attgtgtctg ggctaggatt atagcgaatc gggggttctc
    20041 gggcagcacc gaacagccga cggtgcctcc gaagtgcacg gtcatgcccc gaaggagcag
    20101 ttgtagatcc cccactttcc gaccgtcaac gtagtaatcc acggcgtcgg tcacctagga
    20161 agccattaga gaagatcagt agacttgtgt tcgtagcgtc tgttttgtat ggttatgaca
    20221 gtcgtagtca gatatgatta tagcaggtct acgagtatac aatccagcga gtagtgtatc
    20281 ccgacgattc tgtattccga gaacacaatg cagaacatcc aagtatcttg ctgtataaca
    20341 tacaaatgag agcgtccatc cttcccatta cggtcctcca gattgccccc ggtcgcgtgt
    20401 tcgttgctgg ctgatatacc gtctccactg aacctaagtt agcatagctg catctccgaa
    20461 aatcatcagc aaaaggcggg taagtaccat tggattgtag aagtagacgg gaacccccaa
    20521 cagcagaact ccacccacca cccccgccag aattcccatg gctgccggat aactatactt
    20581 ggccaccatg ggattcaaac catagctgac cccaaagcct atgatgttct tcgtccccac
    20641 gaccgtcacc agcgccggac caggattctt ctcccatgcc tccgtggcaa acgatgtcgt
    20701 gcggatgagg gtcgaaacga aggctacctg atagagcgtc cagcccatga aaggcccgcc
    20761 ccaagtcgca tcgccgctgg cggtgaatcc atataatagc agcgaggcta ctgccaacag
    20821 ccctgggaaa atcaataaga ggagatgatg ttcgggttta tgaacccccc cggcgcgtcg
    20881 ggccaaccaa acaatgacac ggtcgcccaa gatccccgcg tagagcatgc cgcccagccc
    20941 tccaaagacg ccgcctaagt tgatgaggcc aatgctggcg gcaccccagc cgtagttgta
    21001 ctgcaagact gtgtcatagg tgagagagac accgacggac ccgcctagga tgacagcaga
    21061 gagcagtgtg gcatagatga tgccgggcga gctgaaggtc tcgagcatct gccaccaggt
    21121 gagcaggacg tcgcgcaggg gatgagggca gaggcgtggc caagcgctga gcatctggcg
    21181 gtaggttttc ttgggaggcg tgtcgccgtc gaggtcggcg taagagcgac cctcttcact
    21241 agtgaggtat tcttgggttt ctgtggcagt caggactcgg gtcactccat attgatcggt
    21301 gacgacggcg tggtcgccca cgaagattgg ccgacgctgg aaccgcgtct caaagcaggc
    21361 aaacaccacc agcaccagtc cgacggcgac ggttataaca aacacccagt agaaccagcg
    21421 ccagcctagc gcagctactt catatgagct agccagcgtc agaaggctcg tcacgatgtt
    21481 ctgagtggcc cagtagatgc catagatggt gccgcgctgg tgaatgaagg ttacctctgc
    21541 caacatcaga gggagaagct atggtaggtt agatcaacca caaaaaagaa atacagctgt
    21601 cgcaccgatt ccgtcgctcc tgtagcgaat cccaaaagga tgcgtagccc aaaatgctgg
    21661 gcccagttct gtgacaaggc acagccgatc aacgacccca gcaggacggt gttggcgatg
    21721 agcatcaccg gtcgacgtcc gcagacaagg gctaacggca ggatgatgta gttccctgac
    21781 actggtgagt tgctgacggt agcagaactg gaaaagacac cttaccaatt ccgacaaata
    21841 gtgaggggaa agtcgagagc caaacaacct ggttggtgct gtgaccttct gcgccgtaca
    21901 tctgaaagaa aacatccaga acagagccca gcccaccaat gaccgagagt gacatgatag
    21961 ctgagagaat gagcttgaac tcaatagtca attgggggga agggaactta caaaaccaac
    22021 aacagcacac cacgatgcct gtcttctccc acagtgcaaa gttcaagggg tcattgggat
    22081 cgtcgctggg caccggcaga cgctggatgc gaccggcctc gtccaccagc acctgatcaa
    22141 catgctcgat gcaatcgaca tcaatcttct tgtcggccat tctgccggat actcctgctt
    22201 gaacaacaaa tgggtctcat cgcagcgcgc gacggagggt tttaagctcg ccgcttgtgt
    22261 ccactcccga agagactaag catattttag agaatgcggg gaagatatgg ggaatgctgg
    22321 acacg
//
