LOCUS       ch1                    18644 bp    DNA     linear   PLN 26-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   ch1
VERSION     ch1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-03 01:15:18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 541178
            Orig. end    :: 559822
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18644
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[549751:550708](+)"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8574..9530
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..18644
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..18644
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            join(1..131,191..221,285..422,479..779,892..1937)
                     /locus_tag="KYF_000340"
                     /product="hypothetical protein"
     gene            1..1937
                     /locus_tag="KYF_000340"
     CDS             join(1..131,191..221,285..422,479..779,892..1937)
                     /codon_start=1
                     /db_xref="InterPro:IPR001613"
                     /db_xref="InterPro:IPR002937"
                     /db_xref="InterPro:IPR036188"
                     /db_xref="PFAM:PF01593"
                     /db_xref="PFAM:PF13450"
                     /locus_tag="KYF_000340"
                     /note="SECRETED:SignalP(1-24); antiSMASH:Cluster_3;
                     GO_function: GO:0016491 - oxidoreductase activity [Evidence
                     IEA]; GO_process: GO:0055114 - oxidation-reduction process
                     [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_000340-T1"
                     /transl_table=1
                     /translation="MHTIPITVSLYAFLATTFLFSCSAYVAQAPLSDDKCTETTVAILG
                     GGMAGIAAAQALSNASIDDFIILEYRDTLGGRVWHTDFGKDKQGKPYVIELGANWLQGL
                     GSEAIENPVWALAKKYRLKNTYSNYSSIRTYNETGYTDYRYLLDEYAQAYHIAARDAGR
                     ILTQNLQDQTARTGLALAGWRPRKNDMAAQAVEWWSWDWEDAHTPETSSLVFGIAGENL
                     TFNQFGKANHLVLDPRGYSTIIQNEALGFLPNPSDGRLRLNTRVTRIEYSPRGVTIHTT
                     NDNNKNSNTCIRAAYAICTFSLGVLQNKAVTFDPPLPSWKQTAIEKFNMGTYTKIFMQF
                     PETFWPTDTQFFLYASPTTRGYYPVFQSLSTENFLPESNILFATVVDEQAYRVERQSLT
                     QTKDQILNVLREMFPDKHIPEPTAFTYPRWTNEPWVYGSYSNWPAGTTLEMHQNLRANT
                     GRLWFAGEATSAAYFGFLHGAWYEGRDAGENVAALLQGRCVEDVSTTSTASGKEEKEEA
                     CGERVFYEQLNGTTPLDAYSRLNGWPAVSYY"
     tRNA            2079..2150
                     /locus_tag="KYF_000341"
                     /product="tRNA-Arg"
     gene            2079..2150
                     /locus_tag="KYF_000341"
     mRNA            complement(join(2460..2567,2645..4108))
                     /locus_tag="KYF_000342"
                     /product="hypothetical protein"
     gene            complement(2460..4108)
                     /locus_tag="KYF_000342"
     CDS             complement(join(2460..2567,2645..4108))
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 73.1; E-value:
                     2.4e-22)"
                     /gene_kind="transport"
                     /locus_tag="KYF_000342"
                     /note="EggNog:ENOG41; antiSMASH:Cluster_3; GO_component:
                     GO:0005887 - integral component of plasma membrane
                     [Evidence IEA]; GO_process: GO:0055085 - transmembrane
                     transport [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_000342-T1"
                     /transl_table=1
                     /translation="MATCTEKYSPTPTEVFQDHIASNESDTATLSWDDDNDPENPYNWS
                     VGRKWTLTCLAAFTTFLAMMNGTIITVAHFEISEHFHVNEDAFPNSYWPVTTWATGGAC
                     SALFILPLAEDFGTRPIFLTTYLLFICFLVPQAVAHNFATLVVTRFFAGGCVAILANTA
                     AGVVGNLWSTEWSRSIPVSLYILGYMSGSSTGPVIGAAIFHSLGWRWISYMQLIWFGAL
                     FPIYYFFLHESRGSAILARRARRNRKNGDETSGYAGSGDVSSRLNLHSLVVSATRPVIL
                     FSTEPVLFVSTLWSAFTVGTLFLFTQSVEQVFMGLYNWDVSQTGYVQCAIVIGECLGWL
                     VNFLSRKLYFASASRNTEVPGTPIPEARLYMAVVGGVLGLSGGMFIYAWTSYSSLPWIA
                     PTVGLALVGAGSVCVVTGVSDYVVDSYSQFSGSAMGAVAAGENVFSAFLPLATMSMYRV
                     LGYQWASTLLAFICLVLSLIPTLMFVWGKELLAETRTSDGCNSELGNIIASDGEGRSGW
                     TVGSYY"
     mRNA            8574..9530
                     /locus_tag="KYF_000343"
                     /product="terpene cyclase"
     gene            8574..9530
                     /locus_tag="KYF_000343"
     CDS             8574..9530
                     /codon_start=1
                     /db_xref="InterPro:IPR008949"
                     /db_xref="InterPro:IPR024652"
                     /db_xref="PFAM:PF06330"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: TRI5"
                     /gene_kind="biosynthetic"
                     /locus_tag="KYF_000343"
                     /note="EggNog:ENOG41; antiSMASH:Cluster_3; GO_function:
                     GO:0016838 - carbon-oxygen lyase activity, acting on
                     phosphates [Evidence IEA]"
                     /product="terpene cyclase"
                     /protein_id="ncbi_KYF_000343-T1"
                     /sec_met_domain="TRI5 (E-value: 1e-26, bitscore: 89.7,
                     seeds: 3, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTKAQTAVSPDEFFKIITPFLNEINPNIPPYAPDEAFYKEVFDKF
                     AAASGLPEDTIPHFVDTGEVLARCFYPSLPRDLQISIGVLTAYVFSIDDQCADPEFREQ
                     LKSYRSVFLRQSTTDLQYIKGLYNTLHDIVSHYEWYAGDMIIKSTMDFVSINIVEAEQT
                     GDFMVSSSTKLFPDFLRQKSGIGEAYAFFYFPGSDWGLGDYFTLIPDIAGIIEQLNDVL
                     SFYKESVLGNEPGTWVKQTCVCKGISEGEAFKERVDQCLGSIRRLRAASEENPRLVKTV
                     NEFINGYPLFHLNAGRYKLDQFGSYHGWQGEKTAGGN"
     mRNA            17916..18644
                     /locus_tag="KYF_000344"
                     /product="hypothetical protein"
     gene            17916..18644
                     /locus_tag="KYF_000344"
     CDS             17916..18644
                     /codon_start=1
                     /locus_tag="KYF_000344"
                     /note="antiSMASH:Cluster_3"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_000344-T1"
                     /transl_table=1
                     /translation="MAPILLSNNIRTPFRYLNRIIHLRKGKDKGKIRAQPDLSSALTRL
                     FANSENDDEESSITHITESTSQIWVEDQDPALVDLLATLSFTITTSTSDSSTLLALLAS
                     ALDILSTYAQNHKVNTLPIYTALLRHLDTYTSYLIWDHEILLTDAEIIFTASSIPTPKH
                     RDNIILQLESAYVSNYETCKTLVTRLNQLVDIELMERADWIFPRQIGWVEVRREVIRLE
                     KTLKEIRWAGKLKEVEYVNC"
ORIGIN
        1 atgcatacga tacccatcac cgtttcttta tacgccttcc tagcgacgac ctttctgttc
       61 tcctgctccg cttatgttgc acaggcaccg ctgagcgatg acaagtgcac cgaaacaacg
      121 gtggccatct tgtaggagct tcccactaat gcttgatatc gtgttggagc ttagcgtcta
      181 acgttaacag gggtggaggg atggccggca ttgcagctgc agtaggtgac cctcaggccc
      241 ctttgcccta aatcccgacc ggcaatgctc accaacacgt ctagcaagcc ttgtccaacg
      301 catctatcga cgactttatc atcctcgaat atcgcgatac cctaggtggc cgtgtctggc
      361 atacggactt cggcaaggat aaacaaggca agccatacgt gattgagcta ggagccaact
      421 gggtatgaca atctacatac atcccgtcaa atgaacatcc gcctcaccat aacaacagct
      481 ccaaggactc ggctccgaag ctatcgagaa tccagtctgg gcactagcca aaaaataccg
      541 tctcaaaaac acctactcta actacagctc catccgaaca tacaacgaaa ccggctacac
      601 cgactaccgc tatttgctcg acgaatacgc gcaagcctac cacattgccg cccgcgatgc
      661 tggccgcatt ctgacccaga acctacaaga ccaaaccgca cgcaccgggc tcgccctcgc
      721 cggctggaga ccacgcaaga atgacatggc ggcacaagcc gtggaatggt ggagctgggg
      781 tatgaacaat taccattaag agggggaaca cccaaccctt tttacaccca tcgggtcaac
      841 accaacccta tcccatagcc caccctcgac taacgcatat cccaaaacta gactgggaag
      901 acgcacatac gcccgaaacc agctccttgg tcttcggcat cgccggtgag aacctaacct
      961 tcaaccaatt cggcaaagcc aaccacctcg tcctcgaccc gcgcggctac agcaccatca
     1021 ttcaaaacga agccctcggt ttcctaccca acccctctga tggccgccta cgcctaaaca
     1081 cccgcgtcac tcgcattgaa tactccccaa ggggcgtaac aatccacacc accaacgaca
     1141 acaacaaaaa cagcaacacc tgcatccgag cggcctacgc aatctgcacc ttctccctgg
     1201 gcgtcctcca aaacaaagcc gtaaccttcg acccaccttt gccctcctgg aaacaaaccg
     1261 ccatcgagaa attcaacatg ggcacctaca ccaagatatt catgcaattc cctgagacct
     1321 tttggcccac agacacgcaa tttttcctat acgcttcccc aacaacaaga ggctactacc
     1381 ctgtcttcca atccctctcc acagagaact tcctccctga atcaaacatc ctcttcgcca
     1441 ccgtggtcga cgaacaagcc taccgcgttg aacgccaatc cttgactcaa acgaaggacc
     1501 agatcctcaa tgttctaaga gagatgttcc ctgataaaca catccctgag cctacggcgt
     1561 ttacttaccc ccgctggacg aatgaaccct gggtctacgg cagctactcc aactggccgg
     1621 cgggaacgac ccttgagatg catcagaatc tgcgggcgaa tacgggccgg ctgtggttcg
     1681 caggcgaagc gaccagtgcg gcgtatttcg ggttcttgca tggtgcgtgg tatgaggggc
     1741 gcgatgcggg tgagaatgtt gccgcgctgt tgcaggggag gtgtgttgag gatgttagta
     1801 ctactagtac tgctagtggg aaagaagaga aggaggaagc gtgtggagag agggtctttt
     1861 atgagcaatt aaatgggact acgccgctgg atgcgtatag tcggttgaac gggtggccgg
     1921 cggtaagtta ctactagaag tggtatggct ttgtagggtc tgctttagtt gttggataga
     1981 ttggatggat gaatggcgtt ggcatgggaa attacttttt tggaatttca tattagtctg
     2041 catcatgtag cgcaataatt tgggattata catcaactgg cctgctggcc caatggtaag
     2101 gcgcttgact acggatcaag agattgcagg ttcgagtcct gcgtaggtca ttctttttgc
     2161 ttttttctta ggtggagagt ggatctggta cggtggggcg ccttccgtac gggtactatc
     2221 gctggaaatt atctactcgt acagtcgcct ttctctgcgc tcaggttttc tttggggggt
     2281 gtggtatgaa tcggcatctt aagtcggttc ctgtcctttg ttatagcata tgcataattc
     2341 tcatcatagt ctcctagcaa ggtgctaccc aatggagttc aatgtcgtat taatcccctc
     2401 aaactactag tatgctatca atagtatata tttcgggcaa ctactacttc attctaggat
     2461 cagtagtagc taccaaccgt ccagcctgaa cgcccttcac cgtctgaagc aataatgttg
     2521 cccaattcgc tattgcatcc atcgctagtt cgtgtttctg ccaatagcta ccttaaacaa
     2581 cctctgaccg tttcttcgtt gcatcattcg ccatctcatt cataaaagca ctccgtgcac
     2641 gtacctcctt cccccagaca aacattaatg taggtataag cgacaacacc aagcaaataa
     2701 aggcaagtag cgtactagcc cactgatatc ctagcacccg gtacatgctc atcgttgcga
     2761 ggggcaagaa agcagagaag acattctctc ccgcagcaac agcacccatg gcacttcctg
     2821 aaaactgact gtaagagtcg accacatagt ctgatactcc agtcacgaca caaacactgc
     2881 cagcacctac caaggccaag ccaacagtag gtgcaatcca tggaagactc gaatatgaag
     2941 tccaagcata gatgaacata ccgcccgaga gaccgagaac ccctcccacc acagccatgt
     3001 atagcctcgc ctctgggatt ggagttcccg gcacctcggt atttctggaa gcagacgcga
     3061 aatagagctt ccgagaaagg aagttcacta gccagcctag acattctccg atgacgatgg
     3121 cgcattgaac ataaccggtt tgtgaaacgt cccagttata taggcccatg aacacctgct
     3181 caacggactg ggtaaagagg aaaagagtcc ccactgtgaa agcggaccaa agggtcgaca
     3241 cgaagagaac cggctccgta gaaaataaaa tcaccggtct tgtcgcgctg actacaagac
     3301 tatgcaggtt caaacgagag gaaacatccc cgctccctgc ataaccgctg gtctcgtcgc
     3361 cattcttgcg attacgtcgt gctcgtcgtg caagaatcgc gctgccacgc gactcatgaa
     3421 ggaagaagta atagattgga aagagagccc cgaaccaaat gagctgcata tagctaatcc
     3481 acctccagcc taaagagtgg aatatcgcgg cgccaatcac ggggcctgta ctgctgccgc
     3541 tcatgtaacc gagaatatat agactgactg ggatggacct ggaccactca gtgctccata
     3601 gatttccgac aacaccggcg gcggtattgg ccaggatagc gacacagccg ccggcgaaaa
     3661 agcgggtgac cactaatgtt gcgaagttat gagcaacggc ttgaggcacc aggaagcaaa
     3721 taaataatag atatgttgtg aggaagatag gcctcgtccc gaaatcctct gctaggggaa
     3781 gaatgaataa agctgagcat gcaccgccgg tagcccatgt tgttaccggc cagtaagaat
     3841 taggaaatgc atcctcgttg acatggaagt gttctgagat ctcgaagtgc gccacagtaa
     3901 tgatggttcc gttcatcatc gccaggaagg tagtgaaagc agcgaggcat gtcagggtcc
     3961 atttccgtcc cactgaccag ttgtaggggt tttcgggatc attatcgtca tcccaagaga
     4021 gagtcgcggt gtcactttca tttgacgcga tatggtcttg gaagacttcg gtcggggttg
     4081 gagaatattt ctctgtgcag gttgccatgt attcgttgtg cttggttctt actgctcacg
     4141 ataattcacg agtgtatgtc aaatagagat agtaatcatc cgccatatgg ctatggaccc
     4201 tactgtatga cctatatatc attgacagca acatatccag ggctttgtga agcgtcttgc
     4261 ttctcacaat agtgcccttt ttgggaatag ttaattgata gttacttata gtcttggctt
     4321 gatgcagcgg agccctatcg ggaaggctga tggatgcaac tttgcggtaa ctcgcttgac
     4381 ttcgggttcg tgagccgatt agccgccgtg aacacagtgg tatcagtcgg caaccttgaa
     4441 ccgagaaaat gaaaacggtc caacaggccc attgtggaca ttgaatgccc tgcattactt
     4501 ggagttactt tgtagaccta gtatgactgt aaagcgtaat aatgatcata attaccatga
     4561 tgcatgattt ttgtagctat taattacatc cccaagatcc tagtgatacc ggcgatgaga
     4621 aagaacagct gtactatgcg acgatgaagc cacgaacttg caggtaccgg atcacggtct
     4681 ggtagaatgc caggctacaa tgatcattgt cccgatatgc atcggttatg cttgggaatg
     4741 caacttgcgt gactttcctt actaagaatg tgccgaaaag cgactattag cagctgacga
     4801 agatccgact gaagtccagt tcacgagcca atggttcaca cggcgtttta agactagtat
     4861 attgggctaa tcagtctaga acaccatctt acaagtagga atatcggagt gcgtgcaaat
     4921 gcgcgcccgc taatctatga caagaatgag aatctgagcc tcagcagact gagttactgc
     4981 taactcaatt aggtgaacga tcggagaacc agaagaactc tacggatttc gcccgcattg
     5041 ggcttgatga tcttcactgc atatctgcca agtcaatcat tcttcccgag cagcccatgc
     5101 cttcacttcc taatcgagaa cccgacgcct ggaagatccc gagggtatct cggaaaggca
     5161 cccgaaggca tatttacatt gtaacttagg ccatacccgc ggacaggctg aatccagacc
     5221 acaaaataag ttaaactaac ttcggtttgg cgcatccgcg catcccagat atacggtgaa
     5281 gccgaagacc aactgacagt tgggccgtgg accacgggca accagccacc gcgggactgt
     5341 aattataggc cacggtgttg gacccagaaa taccgttact gtccttacgg atatcatatt
     5401 caaggcggct cggctttcaa tgagctagtt taatgtaaca ttcatttctt catttctatt
     5461 gacgacattc tttccttttc tcttgagatg tgctgagtac gaagctgata tgagatgcat
     5521 ctagcgcacc tgtggccgca acgagaagga tattcaagta caaaaattac acacgtaaat
     5581 cacgacaaat tttccacact caaggtactc agggttatca ctacatcatc attcttccca
     5641 tgtcccatgt ttcacgaacg tcatatacca atatcatatc ccaatcagct gctgaccttc
     5701 tctgctagct tgcacctaga tacacgcacc atgagtggtg gcacttccca tgttgtccat
     5761 gaacgatgac ctgctagcca ggggctagat tcattagctg caagttcaca gtcgaactcc
     5821 gttacaaact tgcagaatac tatttttgtc atggcatatg ccatgctatt ttacatatca
     5881 gtcaggcaat tccatgctta ataggtatca gcttcactta ctcttgacca atacaacccc
     5941 gcgggcctgt ggaaaatgga tgaaatgccg ctttgttatc tttctggtac ggtccctctg
     6001 caccatctag ccagcgatca ggaataaatt tgtcagggtt ccagaagtga gtgggggaat
     6061 gtgtggctgc gaaaattgga atatagaccc gcgtgtttcc tgcgacccat cgaccggcta
     6121 tgtgcgcccc gcctgcaggg gtagcacggt gtaaagctcc agggaccggg ggatacagcc
     6181 ttaaagcctc cttgatacaa gcatccaagt acgcgagatt cgacacagat tccagagata
     6241 cctggctctt atcgtgaaac gctgtgcgaa tctcattttt aagacgcgca aaacactcag
     6301 ggtgctcaag gagatatgcg gttaaggctg tcatgagggc tgtggtcgtt tctgctcctc
     6361 cagtcatcat aatgtgggcg ttggcacgga tgtctttttc agtcaacgac aagctgcgac
     6421 tgttgcgaaa tgcaaggccg ataaggtctg gttcgtcgct ttgcaattga agccgacggt
     6481 ctatgaggtc attcgaaggc ttgaagtaag ccttgcggag ccatttcgac atccagggta
     6541 tggtcgaccg gaataaaagg ttgatccagg agaattcagc gagagctgat aataaagtcg
     6601 cggcacgtaa cagcctgtgc tggctgtgta cccacgattt atgtgctcct gttcgcaaga
     6661 cgcccaattc ctcgccaaac tgcaaatgcc caacgatgtc aaaaagcgtg taatggaaca
     6721 tgttgcgtat atttgtgatt tgcccttcta ttccagaaag gctttcaacg agagcgtcgc
     6781 catacttggc aaggattgat tcctggcggg ctaaggctcg ccgtgaaaat gccggtacgt
     6841 atgctcgacg gattcttggg tggtctattt cattggccgc aagaatagag ggccgattgt
     6901 catcatcctc aagatatctg aaaaagtccg accctctccg catactctgt ggctcagtgg
     6961 gagaactgct atatatgtct ttccaggctt gtgggtcgat aaagctcagc tcattcggag
     7021 caacacgtag gactggtcca tatttgagat gaaggttatg gagccactgt gtttgaatcc
     7081 ccttgagtga ggcataagtc acgggaatcc tgctggcggc cagcattcgc gggccgggga
     7141 actctttcag tggatgaatg aacagattat aagtaaccat tgataggtac tatagatcac
     7201 tctcggtctt agttctctca atcactgaag tatcttctga agaatagcag cctttcataa
     7261 ctgaccagaa aaatccctgt tgccacaaga atgcttgcca cgttttcttc cggcatcttg
     7321 gctccgaaga tatgtcgtgc aaggccattc aaatgtcgac ggggagtgtt atatcaaata
     7381 gagggagtga gagaacaatg cagagtggta gattgacttg ctcgtagaaa agttatctcc
     7441 accaactatt ttcagagtcg aataactgca tctacacgag gcatgggaag tcatcaaaag
     7501 tcgatctaca agtggtaagt ttttcaaaca ggacgatcca gggtgtgagt aggatgttcc
     7561 tgtgaccttg tgtaaccgac ctcattattc cataaacccc ttacatcaac caccgctgga
     7621 accataagag gcatacatga ttattccata gccaagggct atatattagc agaagaaatc
     7681 actgtctgct gggtgagcaa taataatggt tcctctatct catgtcaaag cagccgcctc
     7741 gctatagcca aaaattcaaa tcactcatat cggttagtat cttgaagaaa accttgacag
     7801 aagcaatgca cagagatgga ttatcatagt gcccaaatag gacggatgca gagctgtcac
     7861 acaatgttct atacctcctt gaagcgagca cctggatttc ccttgctaac tcggacagca
     7921 cgacacttgc tattagtccc ccggtcattt tcaccgtcaa aagatcaata ccctattgat
     7981 ggtcttgtac gctaattagg gtgtagtagc agaacggttg agatacaaag cacacccatc
     8041 cagagatcag cctatactct tgcaagctta caacattcct cgacccacaa gcacatcata
     8101 cgtcgaggat gcatatctgc aaatccccac ggctgaacac ttgctgatct ctttcattct
     8161 gagtagcttg tgcataagcc attgacttgc acttaccgcg caaacatcat ttcatttgtc
     8221 tataccatta ttcatccatg tcatctcaca caacatgacc atccttgcat gcagatgtct
     8281 catggcaatc tcacccataa tttatcgtca gtgtgacaaa gctgtgcaaa tgcctcttgc
     8341 tccaatgtca atgccagtca tattaaggat atgacgacat tgactttctt atcaaagcca
     8401 gagacaccat tattgtcctt gagaatgtgc gttgaatccg atatggcaac ctaatgacgt
     8461 agtgaaatgt tttttttgac gaacagctcc aactacactc atccgcttta atagtacctt
     8521 cccgatacct agtacatccc acaacaccat aaccatcggc acggtctgca acaatgacaa
     8581 aagcccaaac cgcagtatca cccgacgaat tcttcaaaat catcaccccc ttcctaaacg
     8641 aaatcaatcc caacatccca ccttacgcgc ccgacgaagc attctacaaa gaagtcttcg
     8701 acaaattcgc agctgcctcc ggcctcccag aagacaccat cccccacttc gtcgacacag
     8761 gcgaagtcct agcacgatgc ttctacccca gtctaccccg agatttacaa atatccatag
     8821 gagtcttaac agcatacgtc ttctcaatcg acgatcaatg cgcagacccc gagttccgcg
     8881 agcagctcaa atcgtaccgc tcagtctttc tccgccaatc caccacggac ctccagtata
     8941 tcaagggtct atacaatacc cttcacgata tcgtcagtca ctatgagtgg tatgctggtg
     9001 acatgatcat caaatcaacc atggacttcg tgagtatcaa tattgtggag gcggagcaga
     9061 ctggtgattt catggtctct tcatctacca agttgtttcc ggacttcttg cgacagaaaa
     9121 gtggtatcgg ggaggcttat gcgttttttt atttccctgg gagtgattgg ggtctggggg
     9181 attattttac gttgatcccc gatatagcgg gtattattga gcagttgaat gatgtgctgt
     9241 cgttttataa ggagtctgtt ctgggaaatg agcccggaac gtgggttaag cagacttgtg
     9301 tctgtaaggg gatttctgaa ggtgaggctt tcaaggagag agtggatcag tgcttaggca
     9361 gtattcggag actgcgtgct gcatctgagg aaaatccgag actggtaaag acagtcaatg
     9421 agttcattaa tgggtatccc ctcttccatc ttaacgcggg taggtataag ctggatcagt
     9481 ttggcagtta tcatggttgg cagggtgaga agacggcggg tggaaattga tagtataaca
     9541 ggccaacgca gctggaaggg attggaataa gattgaactc gggtcaaagc atttaagact
     9601 aagaatatac tggtgtcaac aacgtgaaga gggacgttca ttgcaatttg ggggccatca
     9661 cgattctata tactaaggcg gagcgagagt gacagggccg cgttgctcaa acttttacag
     9721 cacaatacta ggataccttt cacaagactc aaagagagga cagtcctttg attccattac
     9781 tgatcacgag gtgtacgcaa gtgtcacact tcctccaaaa agtactcgct tatttccaac
     9841 ccgagtccta aattaggtgg gaaaaaggac cctatgatct gcccagtgct tggatcataa
     9901 ggaaggctct catcgtaagt atcctgagcg gtggtatcct tgtccgtatg catgaggtcg
     9961 ggactttctg aagcaggctg gccttttaaa tgggcttcca gagaagttga cggatctgag
    10021 agcggtaaag gaccacatcc aagttcatta gtctgcggct ctggagcaga cgaaagtccg
    10081 gttggcccag gtccaggcgt aacagaagtg ccgaatctgc tagggatggg cgggttgggt
    10141 aaattcacgc ccgcatattg ttcgatacgg cgcaaaagac cttcgcatag taagcgagct
    10201 ttctccgagg ccgcgttggt atttgcgagt atagcaagcc atttaagtgc tctttcggtc
    10261 gccttagaaa ccatcgatgc tttctctggt acgtgacaaa caccaaaaga cagttccatt
    10321 aaaaggaccg tggttgcttg tacaagaaaa tgcagtatac accaccaagg tgacattctg
    10381 tacagcgcag cagcatctag cccatctggg aacaatctca ccatatggca agctgattcc
    10441 acgcactcag ctgctgttct ctgacagaaa tcctgtatct tttcatctgg agttttgcca
    10501 tcctgattca caggattgga acggcgcaga catggccgtg ttattccaat tttggtgcta
    10561 tagaatataa atgccaggct cattcggtgg ttagatatcg aataagtaac ctgcgtggat
    10621 tgggtcgagg taaagtcaaa ctccttagga aggctcagaa gccatgattc aacgtcagat
    10681 ataagacctt gtatagcgaa ttctatcccc atccaagacg tgctcgctgc tgagggactg
    10741 taaagcttat ttatcatctt ctttgatatc agcatgagcc gaatgacatg gaggaagtgc
    10801 aacgatccgg agggaggacc ggaaattgcg cctgtactct tggagattgc tattgagtgt
    10861 ttgcccatca aatcaaaatc tgtatgaatt ccttcagttc cgtgtgagaa ccggaggcaa
    10921 tttataactt catccttccc gaaatccttt tcgtcaaatg gtactggcag aggtgttgtg
    10981 tagacagtat catctatgaa ggaaggccgt cccgtgatta tgctaagtcg gtgatcaagc
    11041 gtgtagagag accaccatac acgatatcga atctccctgg aagtatccga agcagacttg
    11101 ctcatgttgc gcagatgcaa cccaagacca agggctcccc gaacagcact tccacagatt
    11161 ctccaggcac ttggtatatt cgtaagcact cacatgaata gccgattcgt ccctcccgac
    11221 atgatatacg taccggttga catgccccaa tgaaagcatg tataaagctg ttagcccttc
    11281 cacttgtaat tgctgtaggt caggatgatg aaagctccaa tcatctatac tcaagaccct
    11341 cgctcttgag aaatacaacc agtgattatt cttgttcagc tgccattctg cttcagagat
    11401 gtaagcatac ctagcagcaa tcgcaaataa taggttcaag actgcgagcc acttgttacc
    11461 cgtatgtaac ctggtatcgt tgaagaatgc gtggaactgt tttccaaaag gtgtggttcc
    11521 tatgattggg aaggtaggat gcacccaatc caaatagcag ttgtagagct ttgaagctac
    11581 atcctttgat ggtagtgcat atgcctcttg tcgctcgata tttggcagtt cttgatcatc
    11641 aacatggtaa ttcgatgcgg agataggact actatcagag atcgataaaa atatagcttc
    11701 gctcggagta ccgtgctcag tgtctccatt gatatctcgg cctaatgagt gtatccatga
    11761 tatttcggag ctttgaccaa tataaccagt agcttgggaa atttcgtcct tgttgaagtc
    11821 ttcattgatg caatcaaggc agtggcttga gtcaacatat agtgacaact gggaactggt
    11881 agctgagaga ggtctttgag ttccgggcaa gggggttcgc ccatcgaggg acaaggaagg
    11941 actagaggac tcttcctact tccggtcagt ataaacactc gaagagagag gacgaagagg
    12001 atataacggg ctcaagagga tcaaaggata tggtttcaac gagagcaagg cgaggggcct
    12061 gtattcatac cacagtcaat gcaaggttca tcagctgctc attcgtaatc ccaaatctgc
    12121 tgctcaggtt cttcaaagca tcttcgtaag tccgtatttt ggcctccaag ctagccaatt
    12181 gccttggcgt accaatttct ctgaagtcag ccacggagcc atctaatcag attcagactc
    12241 acctcttgga tttctccctt ttaccatctg tatagcagca aatgatgcca gcctcacggc
    12301 agttgcgaca accggactta tctccagtgc actttgtctt tctctgtctg caggattcac
    12361 atgctcggct cacgtggcga cgatgaaatc tacctggagt tgagaatgtt tccagccctt
    12421 ctgctagcct aggaattgcc atcttcttgc tagtcaaagg atgctccgct ctgtgggagg
    12481 acaatgcatg agatgcacta cccttgagat cctcagttaa ctttcggact ggtagataga
    12541 cgagaggggg atcggatggc cctcaccaca tcgctgtagt tgtgcgaacc ggtcgaggat
    12601 atcctgaagg tcggttgttc tggccaagat ggatactgca ttgtgctatg aaggtctaag
    12661 gaagaaagtc cacaattctg tccaagcaat cattagtagc tgttctgtag cagcgcctta
    12721 gagagctcat cttgatgtca cccatcactg ataccttaga gagttgaaca attgcaggat
    12781 gatacaccag ggtaatcgag aggatgtcga taatgtttac ggaaaaggta gctgagctga
    12841 gtctgaatat ataattttaa gactgagttc ttcaacgaaa gtatagggat gtaactcagc
    12901 ccgaaagaga gtgaaactag ctttgaaaga gtaacgtctc atggttcatc aaatatcgaa
    12961 ccctcgatca gtttcttccc cccaacaaga tttcttttgg tggaaagtgc aggcggaaag
    13021 cgcagtcgtg gctacttccc ttgtgtctct tgtttccctc cagccgaaga tcggcccgtc
    13081 tctgagtcta gatgctaggt accaaattat caaccagaaa agcgagaact ctaggagacc
    13141 agaattgccg ctgatttcca tggatatgaa atggtagagt gctcccagcc ccggaaaatg
    13201 cagggaatgt agacagatta ttctccatga ttagcaagcc gctcactgag taccgtttgc
    13261 ttcaagcgta accgcatcat tctctttgac tggctagacg gcagtgttat gagagagggt
    13321 tgagggcttg acacaaggtt aaatctggac cagttcatcg ttgtatttag gcaggatatg
    13381 gagtacgtga tgggcccacg aggatacttc catcatcttc gttggggcca agctaaacaa
    13441 tgtgctcata gtgattagct tctttgggcg aaccacggtc gacatcagca gagtctgtac
    13501 tgcatgtaac gttctcagag tttctccgtc atgtgcctgc cagtctagcg gaaatcctgg
    13561 ataatggccc agaggattaa actttcctgc gcaactaata cgcatacaga ataaattttc
    13621 cactccatga agcatattaa ggtgcatatt cggacccgac cagccgaata tatccctgta
    13681 tccgcgcacc ctcttcgtag tcggttattt gcagcggctt aaggtgataa tttactgatc
    13741 caagaacatt cgcatgtaca ccatcagaat atctgttatc tctagaaaag tctgacacta
    13801 ccattcgaaa acagattgat gatatgtgag tcaaaaataa ataaaaaaaa cacaaagatt
    13861 tgttatcatg aatcgtacat ataatgtggc ccgatggctt tgttttaaca tgcgtagtgg
    13921 atgataacta ttactcgagc agatgaatta tagttcaaag taggtattga gtgaaacata
    13981 gattcttttc aaattaacag acaatagatg aaatgatctt tagaattcct tacaattgtc
    14041 cactggatgg acgagactgg agttgcagaa tgcggtagcg ggccgggaca acagacactg
    14101 ccataggccc ctcccaggca gatatattga gtatcgtgtt agtcatagtc tagtaatgta
    14161 ttcaggacga aggtgcacca tctgtgatac tgtgacaagc gatttcacca taccatcctg
    14221 atcgattcac ggagtagcct gatagtccat ctccgtagcc ttccagccat aaggaaattt
    14281 catctgcagt gtgcaaactt gagcaggaga tttataggga taatatggtc ctacgttaca
    14341 ctcctaaccc aaaatcgaat cactcattag ttgatcggta ccctccacat ttaccttgtc
    14401 aattgccaca gtatcatgcc actttccgtg tagaatatgt tacctaaagc cttaggcctg
    14461 atccacggta caagggctaa actaaaggct catgttctgc agcctaatta cacataacga
    14521 gaataatgaa ataagtttgt agttttattc agggcttatc tccagaatga acccccacta
    14581 ttactcttaa ccaatgcatc ggtgatatcc accgaacaga attacatctg aagtgatact
    14641 gatgaagaaa gctggcccag acaggcgttg attgctttgg ccaggttgtg gtttcgtgaa
    14701 gcaggaatta gtggtggtgg tggaggacat agagcaggcg ttgtcctgta taccaatttc
    14761 gcaaaccggt gcaaattctc aggaatcggt catattggac tgtggggaat atgaatgact
    14821 ttgactgctg taatagacgc cttgaggctc gatgaggcag tctggttgct ggaagtgata
    14881 taaacagaga ataaggctac agtgaagaac catgcagcct tggctttgcc cgttaaatta
    14941 tcttgagtca cagaactcgc acattttctt tcacggcacg tcccgctttc acgctgcttg
    15001 gttgtgtgtg ctacaatagg tatataaatc cctgcttccc tcgcttttct ctgtctatcc
    15061 aatcttcctt ctcatcacat ctgaagttct gcagcctctt agtcaccgaa acgcatgtta
    15121 cgtatttgat ccctacagtc cgataggtta taataaagcg acctatatac ccgttgatgt
    15181 ctctaccaca ttgtgtacaa tggaaagtgg tgtaccccca aagcttcatg actctcacga
    15241 cacatcgaaa tgctctacgt atcactttgg atatgagact ataactgacc catgctgaac
    15301 atatacggca gatcctcctc tggcccgaag aatgggattc catgacgcta tgcctcgtac
    15361 gaagagagcc accggcgcat ccaccgcaag ctgagggaca gatgaactag aaaccttaag
    15421 agcatacata agagattctc ctcaggctca gcgatatcaa tgagttctga gctttggaat
    15481 gattgagtcg cttcttgggg ttgcgttcgg cacgtatata taatcggaac tggattatag
    15541 gtagtaccta attcacgacg tcatggaaat tcacgcggct gttcttcagt tgaggatgac
    15601 tggctgttgc atatgagcgt gggtaaagga gcattctcca cctcgctgaa gacagcttta
    15661 gaactcgcga agctcctatg cgcaatcatg accacttggg cattcgagat ttttaagtgt
    15721 tgccctcatc tcagtgttgg cagactaagc tacggtccgc tgctcttgag gacgcaggag
    15781 catcttgtgc gctgcgaatc tgtactttcc atcgggatcc cttccggggg tgtcatggta
    15841 gtttaatgcg acagagcttg ccagacaacc gaaatccatg aatgcagcct caatatgcac
    15901 acttcaacat ttcacgctcg cacaaatgct tttacgagcc atggctgcta caagtattga
    15961 aagatacatc aaaaaggaaa agcacaacga cttcctcaca attcagagat tgaggatttt
    16021 tcgtgtaccc agcacggagc aagcatgcca taccggctga tcactcccat gcccacgaca
    16081 gctatggact gcacgccagt ctgagtactg ctggtgtctt cgccgataga aaagacaaat
    16141 aaacagcgaa tcgcaaggca acgaaggata tgtctcacgg gttctctgag aaatgatagt
    16201 ctcatcacgc aattacgtct ccaccagtcc cgaagcccag gtccaccggc gcctgcggat
    16261 ggaagtagca tacaaatatc tctagacctt ttcattatca tgaatcgatt cttaatattg
    16321 tactgtgaaa gctgcatggt tagctcattt caacagtgca gtctctatca ggttgtatag
    16381 tgtgaactgg gctgatggga ttgaagaaca tgaataaatt ctgaacttgg gcgagctatc
    16441 ggctcattcc catttgttta gctttgcgtt attgtatatg ttttctttgg cgggtttaag
    16501 cttattaacg atattcttct ccttccgatg gtgaaggacc tgatggctaa cacctgtgta
    16561 acagaaataa tgagctggaa gactacgaat ttcattgggt aagttttgga gcttttcttc
    16621 atctcgaaga ttgcctctct attaacaact tgtagcaacc ggaaatggca ctgtgatatg
    16681 gcctcattcc ctacggagat atgcgtatgt tcaataccga aggttgcttc accgacgcaa
    16741 tgatatcaga ctagccttcg acataggagg atgactgcta tgggcattca atgtcaattt
    16801 cctactgttg ttagtctatc tccgagcgta gcttttgcta tgacaaaact ggactagtat
    16861 acagttaaag gttgacttct gtgtcttcta tacctgtcat tgacagaccc attcagctat
    16921 ccggcacaac tagaaggagc gtaaaagcca agtaaaacga tatttaggaa atgggcgagt
    16981 acgtcctagt aatttagggg aataaaatcc agaaacatcc acatcgggca ttacatagaa
    17041 actgcagggt gtgattcaac gcgatgtaac cacaagcatg caggctgcat caatattgtg
    17101 atctgcggga tagagatctt ccgatatcaa tgaaaggtcc gacagagcgt cgtgaagacc
    17161 ttcgtactgc tattggagat tatggatcct gacctcttcg acggagtagg caaaggtaat
    17221 ataggattcc atccaagaag agcacaacag gagccgtctt ggaatgccaa gccagtcgca
    17281 agatttaatg gctatggcat gtcaacgcca ttagccatcc ccttccatag aataaaactg
    17341 cgaaagatgc aatcttcatt ctggtagctt ccggcaacat aaagacgaag cgagcgatct
    17401 caggagaagc attccagctt tgtacatttg ctgttgccaa attttgtggc ctaattaacc
    17461 aaatgacttc tatttctgct ggtgacgata ccactacgct gcttcctggc aggaaccgaa
    17521 gtgaccagta tagcctgcga agtcaatatg tcatcaattt ctatattaag cctatgtgaa
    17581 tcaaagtgac ccatggatgg aaagaaaaat ccgagttcaa gaactatatc gtctattctt
    17641 agtttctaat gttctgattg ctgagtatct cttctacaac cctcaacatt atattcaagt
    17701 tttatcattt gaacactcct accctattat ctaccagttt actagcaagc ttcctacctt
    17761 tggaaactcc gctggagacc ataccatcgc taccaaaatt ccgcccgaaa catctcagac
    17821 accgacttcc ctcaaaagct cctctgcata ggcgactcta ttcaccctct gccctgtcaa
    17881 ccaaatcttc agtacccatc ttaaccatct ataagatggc tcctatcctc ctctccaaca
    17941 atatccgtac tcccttcaga tacttgaatc gcatcatcca ccttcgcaag ggcaaggaca
    18001 agggcaaaat cagagcccag cccgatctat catcagccct aacccgactc ttcgccaact
    18061 ctgagaatga cgatgaggaa tcgtctatca cccacatcac ggagtctact tcccagatat
    18121 gggtcgaaga ccaagatcca gccctcgttg acttactcgc cacactctcc tttaccataa
    18181 cgaccagcac atccgacagc tctacgcttc ttgcacttct tgcttctgcc ctcgacatcc
    18241 tatccaccta cgctcaaaat cacaaagtca atactcttcc aatctatacc gccctcttgc
    18301 gtcatctaga cacctatacc agctatctca tctgggatca tgagatcctt cttacagatg
    18361 cagaaattat ctttaccgcc tccagtattc caacccctaa acaccgggac aacatcatcc
    18421 tccagctgga atccgcatat gtctcgaact acgagacgtg caagacgcta gtaactcgtc
    18481 ttaatcaact agttgatata gagctgatgg aacgtgcgga ttggatattt cctcgccaaa
    18541 ttggctgggt agaagtaagg agagaagtta taaggcttga aaagactctg aaagaaatca
    18601 gatgggctgg caagttgaaa gaagttgaat acgtcaattg ctaa
//
