LOCUS       ch2                    22112 bp    DNA     linear   PLN 26-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   ch2
VERSION     ch2
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-03 01:15:18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1547326
            Orig. end    :: 1569438
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22112
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1557326:1559438](+)"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12112
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..22112
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22112
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            complement(1135..2919)
                     /locus_tag="KYF_001798"
                     /product="hypothetical protein"
     gene            complement(1135..2919)
                     /locus_tag="KYF_001798"
     CDS             complement(1135..2919)
                     /codon_start=1
                     /db_xref="InterPro:IPR006101"
                     /db_xref="InterPro:IPR006102"
                     /db_xref="InterPro:IPR006103"
                     /db_xref="InterPro:IPR006104"
                     /db_xref="InterPro:IPR008979"
                     /db_xref="InterPro:IPR013783"
                     /db_xref="InterPro:IPR017853"
                     /db_xref="InterPro:IPR023230"
                     /db_xref="InterPro:IPR023232"
                     /db_xref="InterPro:IPR036156"
                     /db_xref="PFAM:PF00703"
                     /db_xref="PFAM:PF02836"
                     /db_xref="PFAM:PF02837"
                     /locus_tag="KYF_001798"
                     /note="CAZy:GH2; antiSMASH:Cluster_15; GO_function:
                     GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl
                     compounds [Evidence IEA]; GO_process: GO:0005975 -
                     carbohydrate metabolic process [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_001798-T1"
                     /transl_table=1
                     /translation="MLKPQQTPFRDIVSLDGIWKFALGSSDNETATPWTAPLATDLECP
                     VPASYNDIFVDRQIHDHVGWVYYQRQAIVPRGWSQQQYLVRVDAATHKGRIYINDHLVA
                     EHVGGYTPFEADITSLVSAGDSFRLTIAVNNVLTHETIPPGRIEVLEYTGKKTQVYQHD
                     FFNYAGLARSVSLYSVPKQHIQDIKVVTDVNGATGQIKYLVTVTNATTERIKIDVVDED
                     GRTVAEASGTHGNVTIDSVRLWQPGDAYLYQFRVSIVGLDDSILDTYSVATGVRTVKVS
                     GNKFLINDKPFYFTGFGKHEDSNVRGKGYDAAYMVHDFQLMNWMGANSFRTSHYPYAEE
                     VMEFADRHGIVVIDETPAVGLAYSIGAGVSSEDSPQTFTPEGINNNTREAHKQAIRELI
                     ARDKNHASVVMWSIANEPASQEAGAREYFTPLVDLAHELDSDRPICFANYGDATYEVDR
                     ISDMFDVLCLNRYFGWYSQTGEIEEAEAALETELLGWEGKYDKPIVMTEYGADTLAGLH
                     SVLGLPWSEEFQVELLDMYHRVFDRVESVVGEHVWNFADFQAVVGVGRVDGNKKGVFTR
                     DRKPKAAVQTLRSRWSQL"
     mRNA            complement(6540..7178)
                     /locus_tag="KYF_001799"
                     /product="hypothetical protein"
     gene            complement(6540..7178)
                     /locus_tag="KYF_001799"
     CDS             complement(6540..7178)
                     /codon_start=1
                     /db_xref="InterPro:IPR036259"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 76.7; E-value:
                     2e-23)"
                     /gene_kind="transport"
                     /locus_tag="KYF_001799"
                     /note="antiSMASH:Cluster_15"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_001799-T1"
                     /transl_table=1
                     /translation="MPIYFQTVKGNSAQDSGIRTLPLIVSAGVMAVFGAIGFGISGYPT
                     PFLLFGAMLISVGAGLLYTLDLVTLSSHWIPYQILAGLGIGAALQVPIIMNQATVDESD
                     MSTMTSITLFFKCLGASVFMQTGQTIFLEKVKRNLDMMTVADVNPNQILTGGLVRVQAI
                     DSASSIALRTAYLGGLKDVFLLVAALSGLAALLASLMGRYKMDTARLRL"
     mRNA            10001..12112
                     /locus_tag="KYF_001800"
                     /product="terpene cyclase"
     gene            10001..12112
                     /locus_tag="KYF_001800"
     CDS             10001..12112
                     /codon_start=1
                     /db_xref="InterPro:IPR006400"
                     /db_xref="InterPro:IPR008930"
                     /db_xref="InterPro:IPR018333"
                     /db_xref="InterPro:IPR032696"
                     /db_xref="InterPro:IPR032697"
                     /db_xref="PFAM:PF00432"
                     /db_xref="PFAM:PF13243"
                     /db_xref="PFAM:PF13249"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: terpene_cyclase"
                     /gene_kind="biosynthetic"
                     /locus_tag="KYF_001800"
                     /note="antiSMASH:Cluster_15; GO_component: GO:0005811 -
                     lipid droplet [Evidence IEA]; GO_function: GO:0016866 -
                     intramolecular transferase activity [Evidence IEA];
                     GO_function: GO:0000250 - lanosterol synthase activity
                     [Evidence IEA]; GO_function: GO:0042300 - beta-amyrin
                     synthase activity [Evidence IEA]; GO_process: GO:0019746 -
                     hopanoid biosynthetic process [Evidence IEA]; GO_process:
                     GO:0016104 - triterpenoid biosynthetic process [Evidence
                     IEA]"
                     /product="terpene cyclase"
                     /protein_id="ncbi_KYF_001800-T1"
                     /sec_met_domain="terpene_cyclase (E-value: 3.1e-23,
                     bitscore: 79.1, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MAHQETMASETSISLHTLACDATKLAGTYALRQVREDGHWYGEMK
                     SNATITAEYVFLAQALGFSIEEDRDDLIKYFLSEQNTDGSWSLAYDFPGDVSVTAEAYF
                     ALCLLGLDRSHPAMASAREFTLSKGGIAKVRVFTRMFFACFGLFPWSAVPELPAELILL
                     PAAAPMSIYQLASWARATVVPMLVIRHHRPIYALPNGRSSSNEYLDELWVDPTDKMVPY
                     SPSLWSLWNDDLTAFGFTLADNILKALGGLRWFPSRKIALRHCVAWILERQEPEGDIGG
                     IFPPLHAALFALALEGYGLESSPVRRGIDALQNTYAWRDSTGLRIQGCISPILDTILMT
                     IGLIDSSLPAESPLVARSSRYLKAHQQLGNEGDWRVYNGNVPSGGFNFEYFNSWYPDID
                     DTAAAILAMVKQDPNLLDLGPILSAVQWILGLQNDDGGWAAFDRENNYLFLNKIPFSDM
                     DSFCDPSTADVTGRVIECFGLLAKRGSVLSRNGKNPIPRFFIDDMSSATERAIDFLSTE
                     QEADGSWYGRWGSNYIYGTSAVLCGLVYHLEGWDDTYPVMEKRHKVDTHAALDWLKRHQ
                     NPDGGWGERLESYYEPSLAGNGPSTASQTAWALMGLLAYLAPTDESITRGIQYLSRTQI
                     KEGELAGSWKEDHYTGTGFPNHFYLCYTLYSQYFPMMALGRYTSLSGYRPLENLESTVE
                     DHKGNSSDC"
     mRNA            complement(join(12221..12506,13111..13262))
                     /locus_tag="KYF_001801"
                     /product="hypothetical protein"
     gene            complement(12221..13262)
                     /locus_tag="KYF_001801"
     CDS             complement(join(12221..12506,13111..13262))
                     /codon_start=1
                     /locus_tag="KYF_001801"
                     /note="SECRETED:SignalP(1-16); antiSMASH:Cluster_15"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_001801-T1"
                     /transl_table=1
                     /translation="MRLLTYLLLTIYATSAVSTDLSVEEECGSLGVMKVDPADLPEGVT
                     LADVRKDAPPAKRLLDEDIDGALDLPALAIAPAVIEIGAIPPQQCTRAHHRARSNVYPR
                     KPHRSVPQHGPIFDDNGLPAQPVHRAQARPIAKHHIVPNIH"
     mRNA            complement(join(13790..13915,13980..14078,14128..14227,
                     14281..14591))
                     /locus_tag="KYF_001802"
                     /product="hypothetical protein"
     gene            complement(13790..14591)
                     /locus_tag="KYF_001802"
     CDS             complement(join(13790..13915,13980..14078,14128..14227,
                     14281..14591))
                     /codon_start=1
                     /db_xref="InterPro:IPR000782"
                     /db_xref="InterPro:IPR036378"
                     /db_xref="PFAM:PF02469"
                     /locus_tag="KYF_001802"
                     /note="SECRETED:SignalP(1-20); EggNog:ENOG41;
                     antiSMASH:Cluster_15"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_001802-T1"
                     /transl_table=1
                     /translation="MIFSFAPIIGLLSLISPVIATTDPLNYRNIPGYVTSSSLNVTTLV
                     DFIKSRSDLSILSEKIDELGGFAQAFDTDPNWKFTFFAPNNDAFELYTGAYFDSFEPTP
                     KGKWWLGNTIIHHYVPNSRLTSSSFNETLQRFQTATYLFVGSQMQDGAIVLNQVANVVE
                     SDIPVTSGVVHIIDRILDPSTQIFEPDLPRLSQTFIAGSCSNPELSYC"
     mRNA            join(14964..15570,15635..16257)
                     /locus_tag="KYF_001803"
                     /product="hypothetical protein"
     gene            14964..16257
                     /locus_tag="KYF_001803"
     CDS             join(14964..15570,15635..16257)
                     /codon_start=1
                     /db_xref="InterPro:IPR002241"
                     /db_xref="InterPro:IPR013780"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="InterPro:IPR017853"
                     /db_xref="InterPro:IPR041233"
                     /db_xref="PFAM:PF16499"
                     /db_xref="PFAM:PF17801"
                     /locus_tag="KYF_001803"
                     /note="SECRETED:SignalP(1-27); antiSMASH:Cluster_15;
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]; GO_function:
                     GO:0003824 - catalytic activity [Evidence IEA]; GO_process:
                     GO:0005975 - carbohydrate metabolic process [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_001803-T1"
                     /transl_table=1
                     /translation="MMKRKSQLSSFTLVTAAILPFAHLVMGGTSLAQKPQMGWNSWNAF
                     KATVNYTIVQEVISLFDTLGLKEAGYEYVLLDDGWASYNRTSDGYLQANATSFPQGIKA
                     LAQEVHGKGLKLGLYGDSGHYTCAWRPGSWGYEERDAQTFAGWGVDYLKYDNCGGFQSM
                     TEAPQIRFGAMKNALTLSGRDIFYSVCGWGYQFPWHWGGDIGHSYRMSGDITTSFTNET
                     ECQCKTAYCLNTGYAGCSVLTIINKMKEISQYQTPGHWLDMDMLEVGNANFTLNQQQTH
                     FAFWAALKSPLIIGADLSKLSNDSLAVLTNKAIISINQDALGEPVTYREAHSKEGLFQV
                     WAGKVEDGYVVLLLNEKSYPQTVSLSFASLGLGSPQKVTELWSGQTLQDLSKFNGTLGS
                     YQTLVFKVKA"
     mRNA            17768..18676
                     /locus_tag="KYF_001804"
                     /product="hypothetical protein"
     gene            17768..18676
                     /locus_tag="KYF_001804"
     CDS             17768..18676
                     /codon_start=1
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR007219"
                     /db_xref="InterPro:IPR036864"
                     /db_xref="PFAM:PF00172"
                     /locus_tag="KYF_001804"
                     /note="EggNog:ENOG41; antiSMASH:Cluster_15; GO_component:
                     GO:0005634 - nucleus [Evidence IEA]; GO_function:
                     GO:0000981 - DNA-binding transcription factor activity, RNA
                     polymerase II-specific [Evidence IEA]; GO_function:
                     GO:0008270 - zinc ion binding [Evidence IEA]; GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_process:
                     GO:0006355 - regulation of transcription, DNA-templated
                     [Evidence IEA]; GO_process: GO:0006351 - transcription,
                     DNA-templated [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_001804-T1"
                     /transl_table=1
                     /translation="MPPKSHPATANANVGDLPETTNKGEEEIPACQFCRKKKAKCNRAQ
                     PCSQCMRSDVLCVYDDRRTKPGLRAGAVDQLYRRVETLENMFLGQEMLWQQMWKALFPN
                     TEPPRSLDKGTTAATTLTERREQLKASLQEPPPLAAKRSLTVADADNSAPLDCVPLPAK
                     RARVEDEVAPHAAVLEPEPFLANSLPDIVLNELVDFYFVNIHPWIPILHVKRFRERMRS
                     PEERGHINCILHAIISVCARFSQNGPNGDTLNLKEIAKKSRQEVILQSTETFSVENLQA
                     LVIVAFETVSKRPTPWISGNK"
     mRNA            18741..20285
                     /locus_tag="KYF_001805"
                     /product="hypothetical protein"
     gene            18741..20285
                     /locus_tag="KYF_001805"
     CDS             18741..20285
                     /codon_start=1
                     /db_xref="InterPro:IPR007219"
                     /locus_tag="KYF_001805"
                     /note="EggNog:ENOG41; antiSMASH:Cluster_15; GO_component:
                     GO:0005634 - nucleus [Evidence IEA]; GO_function:
                     GO:0008270 - zinc ion binding [Evidence IEA]; GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_process:
                     GO:0006351 - transcription, DNA-templated [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_001805-T1"
                     /transl_table=1
                     /translation="MAGTVEQLQLGVEEDDLYRVKRMGERLIRRMVFLTPSRSWSEAEE
                     RRRVFWAVFLMDRFCSVSTGWKISLRNADVKRRLPCEGALWEKEQEVCTPYFGISDFKN
                     TSMPNSHSTSMDGSEEQAIGAFAYIIEATESLALVTNFYLHHVFLINDASKARLWLVKF
                     KELDLRLIQYVSSLPKGCLNTSDADARRWKIHLPPKWREACVLNEHRVMDPNLTLAHIT
                     HNTAVILLHQGIAYPPSHWQYCPIKLPSASSADTCLEAASEIATIANKFLSFSPIFTNP
                     QFSFCLFIAGRTLLAHARYNRVPPSPALNTLIANLMEISQRWTRHHDASESQQEESLAF
                     KFATRLIEAQQNRTSASRPSLDIRTTAYSDESKEEMYKDPMRTNQDDLPDYESLSRPLQ
                     LASFPSQESTSCTFDPFSLAFPPLPPAFQQDFSPTGLDPLSFYNMQLPSESMSSPLGTR
                     SHGSGSQHDSESSMTSLLPTDISHLFDMTSSPGQRISYYGNTRGVTNNSIVEGADN"
     mRNA            complement(join(20412..21683,21748..21891))
                     /locus_tag="KYF_001806"
                     /product="hypothetical protein"
     gene            complement(20412..21891)
                     /locus_tag="KYF_001806"
     CDS             complement(join(20412..21683,21748..21891))
                     /codon_start=1
                     /db_xref="InterPro:IPR008928"
                     /db_xref="InterPro:IPR010905"
                     /db_xref="PFAM:PF07470"
                     /locus_tag="KYF_001806"
                     /note="CAZy:GH88; EggNog:ENOG41; antiSMASH:Cluster_15;
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_001806-T1"
                     /transl_table=1
                     /translation="MSIEAGPPTTINGTEVLPTKQWARVLEALFSESLLAKVWFVASKA
                     MGSTTPPTFYPEYTGEDKTTYIYRTLDFWTSGFFPGSLYLLLERSTLFRDRHLILQRQT
                     SESILHPHPLQHEHLCRWWTANLHQNALRKDTHDLGFMITPWAMKAWTLHRDPAAYNTL
                     ILAAHSLASRFNESTQCIRSWDQCITKRYAYRNSSQDFLFIIDNMLNLDLLFWAARETG
                     CRRLYDIARAHAITTQKHHIRDDYTTFHVVDLDLETGEVKKKFTNQGYSDDSCWARGQA
                     WGIMGFAQTFEWTREMRFLRTARALADVFLARLPDDGVPYWDFDAPVTDTSPRDTSAAM
                     IAACGMLLLYKAYKKMHDVEAANHYLRAAMKLVDCTVVGYLNPPMRFEAGPASEISVYA
                     DQCSTHHTETRNGAEVLRVVGDVAETILTGATINNYEFAPRRWSDHGLVYADYYFLLFG
                     NMLLEMDLVDPHI"
ORIGIN
        1 aggatgtgta tgataagata cgacgacagt taattatatg gacttgcgta cactcaggga
       61 tgtcatcaca acggcgaccc tttgcttgct ctgatgatca gtgggaaagt catcctcagc
      121 tgcttcggta ggggcatctt ttcccagatc atgcttgaaa tggttggata ggttatggtc
      181 ctcttctagg tgttggtacg gtcggggaga gggatcttgc tccgtattga cagccatgta
      241 acagagactg gcgtgaagaa ttgaaagaag aaaggaatgt gagagctctg aagaagaggg
      301 aaatgcaata acaagtggaa atgatgaacg agcggattcg actaggtgct gtgcagaaga
      361 ataaaatatc ggaaaaagct gtggtgagat agtcttcccc ggacaataat catcagagtc
      421 cagaggactt aatatgtagg cagcactcct tgacaccctc atgggcagca tgtggggaaa
      481 tggatcgatc atcaatttac acaacgtcat ggctattcta ggctctgatc acgatgctga
      541 ttactggttg gatctgtctg tgtctaaggt ggagaagaag gaacatcaag aaaggggcag
      601 cagagagggt ttgcgctcgg cacagacata agcgatgtct ggttttctct actatgatac
      661 taaactattc tatatggcta ctattcaagt tagttataat tcaatataat atgttcattg
      721 atacaagggg tgtgcctcat aaaatcgctg tatcagtcct ttactggaat gacagcatta
      781 gggggacgga cccagttgga aaaggtccta ctggccgatg agccgctcgg caaatctaca
      841 ggaaaaaatt caacacacgt ggcctgcaat tgtgggcccc aattcccttt ctctgactgg
      901 taaatttaaa gccggaattg ccagtagaca atcgacaccg gcccgtaccg tgagatggga
      961 agagagttgc gaagaagctt ggcctcgtta ctggataagc gggccatcca caggccttct
     1021 agcagtcgcg cattcgaata ccctaaaagc aaagaccggt tttcccgccc ctaaagcccc
     1081 atgatattgg ctgcacatga ttaacctttc aaataatatt cgtaactccg caccctacaa
     1141 ttgactccat cgacttctca gagtctgaac tgcagccttt ggtttcctat ccctggtaaa
     1201 gacccccttc ttgttcccgt ccaccctgcc gacccctacg accgcctgaa agtccgcaaa
     1261 gttccaaacg tgctctccca ccactgattc gacacggtca aacactcgat ggtacatgtc
     1321 gagcagttcg acctggaact cctcgctcca cggaagccca agcaccgaat ggaggccagc
     1381 caaggtatcc gccccgtatt ctgtcatgac gatgggtttg tcgtatttgc cctcccagcc
     1441 caatagctct gtttcgagag ccgcttccgc ctcctcaatc tcaccggttt gcgaatacca
     1501 cccgaaatag cggttgaggc agaggacgtc aaacatatcc gagattcgat ccacctcata
     1561 tgtggcgtct ccgtaatttg caaaacagat ggggcgatct gagtcaagct cgtgggccag
     1621 gtcaacgagt ggcgtgaaat actcacgggc tcctgcttct tgtgatgcag gctcatttgc
     1681 aatcgaccac atgacaacac tggcgtggtt cttatcccga gcaatgagct cccggattgc
     1741 ttgcttgtga gcttcgcggg tgttattgtt gatcccttcc ggggtaaatg tctgtgggct
     1801 gtcttcgcta gaaactccag ccccaatgga gtacgccagg ccaacggcgg gcgtctcgtc
     1861 aatgacaacg attccgtgcc ggtccgcaaa ttccatgacc tcttcggcgt acggataatg
     1921 cgaggtgcgg aatgagttgg ctcccatcca attcatcaac tggaaatcgt gcaccatgta
     1981 cgctgcgtca tagcctttgc cgcgcacatt gctgtcctcg tgcttcccaa agccggtgaa
     2041 gtagaacggc ttgtcgttga tgaggaattt gttaccgctg actttgactg tacgtacgcc
     2101 cgtcgcaaca ctataagtgt caagtatact gtcgtccaag cccacgatgc tcacccgaaa
     2161 ttgatacaga tatgcatctc ccggctgcca cagcctgaca gagtctattg taacattacc
     2221 atgagtacct gaagcttcgg ccacagttct gccgtcctca tcgaccacgt cgatcttgat
     2281 gcgctctgta gtcgcgttgg tcaccgtgac gaggtatttt atctgcccgg ttgcgccgtt
     2341 cacgtccgtg acgactttga tatcctggat gtgctgcttc ggaacagaat acagcgagac
     2401 ggagcgcgca agtcccgcgt aattgaagaa atcatgctgg tagacttgcg tctttttacc
     2461 tgtgtattcc aatacttcta tcctgcctgg cggaatagtc tcgtgagtca gcacgttatt
     2521 gacagcgata gtcagtcgga agctgtcacc agcagagaca agactcgtga tatctgcttc
     2581 aaaaggtgtg tagccgccca catgctcggc gactagatgg tcgtttatat agatacgacc
     2641 tttgtgtgtg gcggcatcaa cccgcacgag atattgctgc tgtgaccagc ctctggggac
     2701 aatagcttgg cgctggtagt aaacccatcc gacatggtca tggatctgac gatcgacaaa
     2761 gatgtcgtta taagaggctg gaacgggaca ctccagatcg gtggctaatg gagctgtcca
     2821 gggtgtcgcc gtctcattat cgctggaacc gagagcaaac ttccaaatcc cgtcgaggga
     2881 gactatatct ctaaaaggtg tttgttgggg cttcagcatt gctggtctct gctggaccat
     2941 ttgacgtggg tgaataagtg aagggttaga agatacatgc tgaattaggg aaagtattga
     3001 caatcctaag aggaccttca tcatgacaga gtcaagggag aaatcaccag ttttctcgac
     3061 atcgccagga gtagctacat cggtgacgac gtgagctggt aattggtatt aaatgataga
     3121 aggcggcaat tgactgccac accgtcggct gttgatgcac ttgtcatgtt attgcttggc
     3181 aaggactaat tctttaattc caacagtaat atctagtcaa tgctcccttg gcagcattgc
     3241 caagcacatg tctcttttat tctttgcaga tgtggtcccg aaatggaccc gaagagggtc
     3301 caggatgcag ccaagaacca aagtgcggag aaaatagagt ttggtgccct ccaacccgat
     3361 ggataccgtc atcatcaatt gccgaccaag gatggacttt cttgaatgtc tttggagagc
     3421 atgatgcttc cagcgaggcg atagatggcg accctaattg atatcagtcc ttatacgtac
     3481 cacctagctg tgactgtgtc agctaggttg tattatattt gaaagtactt gacaataata
     3541 gtcataggaa ttgcattact caccttcgca ggaatacttg tctcttgtca ttccattgaa
     3601 ctttggactc tattatcatg gaaatgcaat tctcccattt gcgtcggcgt agcgaggcta
     3661 atatgaagaa accttagcct ctcaccaagc attctacatc tgatcattga ataaaaagct
     3721 tcacctgcgg tattatagcg gtacaaataa tggctgcaat tttcattgac tgacccgttt
     3781 caattacttt tgaatcaatc gatcaactat tgggtcacaa ggaacaagga catggtatca
     3841 gggggaataa gatgtggcat tccatgagaa tggaattttt gagactgaga tcaaccagtt
     3901 gggccttcac ggccggatgc gtgtagcgac gaagacgtaa gcggatgagt cgaagatggt
     3961 caaagtgaat ttgggtattt ctggtgttca cagatgaaca gcactaggaa aagtgatgag
     4021 cagtggatga accggctgaa ctacgttgac cacggccggt gaagttaaac attcatccat
     4081 gacatgctat accaatgcat tgaatgcaca ttttttgtgc gctgattaac gcaacgcact
     4141 gggcgtcact gtgtagaaaa atattacatt cacctttggg gtaaactacg taaacagatt
     4201 gggatattta atcccacctt ttaccccccc gaaatgcctt cccctttctc ctctgaacat
     4261 gatcgttgaa tcccccaatc tgatgagatg tacctgggtc ttacctatta tacagatccg
     4321 ggcacttccc gtcaacgtca ggtactccgg catatataaa ggtctccgtg ttgtcgtttg
     4381 gaatcttcct accactcggc aacatcgaaa ctcaagtgtt gatcttttac atttttacaa
     4441 acatgtcaca atggcgacac ctcctcccac agatacaacc tcacttgaca aaacagtcgg
     4501 gaaaagagaa gagctcctga gcgacacagc aatgacaatt ctaactcaac ttagtgagac
     4561 atcgaatatc ttcttccagc catcctgcac ctaacaggac agacctttct gttatttctc
     4621 actcatcctc gttgcggaca tacatcagtt ggcaagttat atgtactggg caatttcgtg
     4681 ccacggtggc tgtgtggagt tttcatcgaa ctgtacaatg tccatttttg aatgggatat
     4741 cgctatattc tacggaaatg gacatgctcg ggcattaaga tccatcaaaa gaccgcagac
     4801 ttctaaaagc aattatatac atactggagt tacagaggag ttacagaatt gtctagaatc
     4861 tcaaaaacgg acaatcatcc atattgaaca agacgatgct ttaagtgacc aacagcatga
     4921 atcacatatg attattccca gaatgaaagc ccggttggag agccgcaaag gatgcgggta
     4981 tttcgagagc taaagggaat aggacatgtt gactagaaag ggagggccat gggagagttg
     5041 atgaggtagc acagtggctt ccaccagctc ttctgttgtg gattatcttg tgtctgaaga
     5101 tatgttctgg tgagtcgact ttaccacagc aaaggactgc gattaatgct gaccgagatt
     5161 agcttcttga tagtgctctg ctacggccta acaacttcca gtacaaataa aaccgaaact
     5221 ggatgattat tgtcttcttg ttgtgacgtt gagacattat gagcacttgt ttgctgttat
     5281 tgggagaaca tggctctatc agacatccaa atttacagca gcagtacagc tttaaactca
     5341 gttaagacat tgattaccgg ataatgtctt tcaggaagga gaatagtgga tgcactatca
     5401 tttttgcaga catgtgatga tcataaatat attttgatat gatgactggg ctgtggctcg
     5461 cattagagct tggttgtgac ttctgaaagg tacgtgaatg tattaccctt ccaggagaga
     5521 acgagaacga atgaacaatt cacttatcca atacatgttt gctaactata gagcacctta
     5581 ggctcacatg gcaccataac atgctcgata ttgctcgctg ccacaaaata tctttgttca
     5641 cggccatgca ctctgcctgg ttcactggtt cacagtctac ctacttgctg ccccacatta
     5701 taacttgctc gctgccacga gctctctttg tttacaaccg ggaatcctgc ctttctcgct
     5761 gccgcagaag gatcctactt cataggcttt ccgtatacag cctacttctc agggaattgg
     5821 cccatatcct ccctcacgaa tggggttgct ccaaaggtat aaagcctttc tcccaccatg
     5881 tcggttgtct cgcttttctt tactctccca gttcccactg ctctgctcag acattgttcg
     5941 taacaatggt ttgggacgag ttggataagg ttttgctagt cataggtctt attggctttg
     6001 ctatcgttct caaaaacgag gcacccaagc ttcgaaagtg gtatcgcaag cgacaggacg
     6061 ccaggcctga tcaaccgggc gcctctgtaa tccagcggct ggcagcgatt cgttcgccac
     6121 ctccagcttt gctgccgatc catttacatc caccaatcga actcgacttc tgggagaatt
     6181 aaggtgccct tggggaaggc actcgtactg aggacgcagg gaacggggag atcggatgtg
     6241 gtatggaaat gaggcacagt ggtagctgcg tgaacatttc gttggcttgg gaaataatct
     6301 ctgattgagc ggttggtaga gtttgggggc gcccaccggt gatgagtcta cccttctacg
     6361 tagggccggt gattagtagc cttcgggcga agctaagatg gactcagatg taattagatt
     6421 gaatgcaagt attttgtatt ttgcatgtat gttcttcttc tcctagctct ttccaacggt
     6481 gttgcttctc taaactcgag tttgagaaaa ccgggttatg agaaacgtaa ctcgactatt
     6541 catagccgca gtcgtgcagt atccatctta tatcgaccca taagtgacgc aagcagagcg
     6601 gcaaggcccg agagtgctgc taccaacaag aatacatctt tcagacctcc aaggtacgca
     6661 gtgcggagtg ctatacttga ggccgaatcg atggcttgta cacgcacaag gcctccggtg
     6721 agtatttggt tggggttcac atcggcaaca gtcatcatgt ccagattccg cttcaccttc
     6781 tcgaggaata tggtctgccc tgtctgcata aataccgaag cccccagaca tttgaagaac
     6841 aaggttatag atgtcatggt tgacatgtcc gattcatcga cagtagcctg gttcatgatg
     6901 attggtacct gaagtgcggc tcctatccca agccctgcta aaatctggta cgggatccag
     6961 tgactcgaca gcgtgacaag atccaacgtg tatagcagtc cggctcctac actgatcagc
     7021 atcgcaccaa acagcaagaa cggtgtcggg tagccgctga taccaaaccc tatcgctcca
     7081 aatactgcca taacgccagc tgacacgatc aatggcaggg tgcgtatccc tgagtcctgg
     7141 gctgagttac ctttgactgt ctggaagtag atgggcatgt aatataggag catgaaaaac
     7201 gcgcccgcca ggagaaaaat gacaatgaga ttgacaacaa cttctttctc gagaagcaat
     7261 cgacgtggaa tcatcgcccg gtcatcccag aagaattcat tcgtgatgaa cagccctgtg
     7321 aggattggaa aaccgaccag acatccaatc acatctctat catgccagga cttgctcact
     7381 ccccactcaa ggctgagtag aaaacagagt aatgcacctc ttaatgtaat gacccccggt
     7441 atatcgagct ggaggatgat ctctttccgt gatactccta cattcgcgcg tcgaaagggt
     7501 ggccgaaata agaggaggag gacagcgaaa gtagctccgc caacaggtac attgatccag
     7561 aagcaccatc tccaagttaa gttgcttgta aattctcccc cgataacggg gccggcaaag
     7621 ctggcgagca agaatgccag acccgttacg ccaaccagta tagggcgttt tttgggtggg
     7681 acgcagaccc caatgaccgt atatatcccc gacccaatgc ctgatccacc tattcctgca
     7741 attgctctgc caattatgaa tgttggggag ttgtgggaaa tagcacaaag caaagacccc
     7801 aactcaaaca tgagtaggct gaggaggtag gtccatttaa tatcgaaaag tccgtatagt
     7861 tttccccatg gtgcttgagt tacagcgctt cccagaagaa atgcagctcc ataccagcca
     7921 acatcagcag tggagttaaa ttcgtctgtg atctgaggaa tagcggttga gataatagtc
     7981 gtgtcaaggg aaaccaggaa catggccaca gctaggcaaa gcacaatcac atgcaataac
     8041 accccatcga tgtatttctc atgtgcatca gaatctctgt cggtatctcg atgactgact
     8101 actttggttt catgcagcgg agattcgctg tcaacttgtg acgttgctgt ggtcggcggc
     8161 tttaacgccg tcaaatcact gggatctgat ggcatcttgc ggccttgtcc tgaagatgca
     8221 aaacacaaca gctgcaggaa ggactcagca cgaactggaa tgagcaaggc gaaaaaaaag
     8281 tctaaacaaa tgggtttgct tttagtcttt caccgctgcc tcggagaagt caaagcatgg
     8341 gtatagacac tttcagaatg ggctttcaca gaagaaattg actggtaaaa tgctaagttt
     8401 aaaatttgca tagcatggcc ccaaaggatt gcttcattac caacgcagac tagggtggcc
     8461 cttcctgtcc tcacaaatta ccggctggct gggaaagctt atcccatatt atcattttaa
     8521 tcacttcaaa aaagagtaat gatcgtccaa gacatgctcg tttgcgattt acccctgcaa
     8581 ttattttaca ggtcgggagt agacacatta ctccgtacag tcttaggcaa tgtaagtcga
     8641 acaaggactc ctcaggattc cggacccaca tgtctcgatc tatgtggctg cctgacatgc
     8701 agagttgccc tctctcctcg gaaaggccaa agatatgatg tcgatgagct caggtatata
     8761 cgcgaaaaca tttcaatcga gtcttttgta atcgcagacg gttctgatta gtaggggttt
     8821 aatccaagtg tgggaacttg tattaagtat agtattcatc tgcttcaaga catgtctatc
     8881 tattttccat taagattctt cagctcttag gaaattacgc aagaagctat cgatatgcag
     8941 aatcatacaa gatgatgcat tgagacacct cagaactaac gtttcgcttc cgatcggtca
     9001 gatctttagc aaatgaaaat gtcctcataa attgtatctg acggatcaca taacaaggag
     9061 gcaacgataa caacatagcg ggccataata tagcattata tagtagtata tttgttttca
     9121 gttaattatt aggttttttc ttttcttctt ctttccgaag aaggaaagaa agagaacgag
     9181 acttacagat tcctgctttt tcgatgcatg gtaaataccc actgaagtat cagccagcca
     9241 tttcactaaa gagtaataag tgaaaagata cagtcgatac cccttacaga ctccagtgca
     9301 aaataaactt tggtgttagc tatgcaggac ctagatacca agaacaacca ttgttcatga
     9361 aaggaaggga cagggaaaga tgggaaatac tcccttgttt cctttctttt cttttcttcc
     9421 ctgttttttg ttcattcatt attactctta caggaattat gaaaatatga tacatggatc
     9481 atatctagtc aacctggctg aagttttgac aatccctcaa gatctgtcta cagccacctt
     9541 tctgattatc tatgctcgat tgcagccaca tgtttactat tgcgttctat caagggttta
     9601 ttatatttat taatgttata atcgagttat cacctactcc atcagaagcc gagaaggaag
     9661 aagatgatga gaaagatgaa ttctgcaagt tctagacaac tatactctcc accagtgggc
     9721 cggcccgggc aattgtgaaa ggttagccag gcacaaagat gccattccct tgcactcaca
     9781 tgctccactg tagagtagac ttgtgttgac tgggggactc aggcaccgtt tgccaatagt
     9841 actgctttga tggtggatca atgggtccgg gtctcattca gctaacttta atgccccctt
     9901 gagtggcaag tccggctaaa tagatgctgg acgcccgctc attttaccag gaaatcagca
     9961 agccctgagc aaactcacaa tttacctttc tttggatacc atggcacacc aagaaactat
    10021 ggccagcgaa acttccatat ctctacatac cctggcttgc gatgccacca agctcgccgg
    10081 cacatacgca ctgcgccaag tgcgggaaga tggtcattgg tacggtgaaa tgaaatccaa
    10141 tgctactatt acagcggaat atgtctttct tgcgcaagcc ttagggttca gcattgagga
    10201 agaccgggac gatctcatca agtatttcct ttccgagcaa aatacagacg gttcatggag
    10261 cctggcatat gactttcccg gggacgtttc tgtaaccgca gaagcctact tcgccttgtg
    10321 cctgttgggc ctcgaccgca gccacccagc gatggcttca gcgcgcgagt tcaccctctc
    10381 caaaggtggc atagccaagg tacgcgtgtt tactcgcatg ttcttcgctt gcttcgggct
    10441 atttccttgg tctgcagtgc ccgaattgcc agccgagttg atcctactcc ctgctgcagc
    10501 cccgatgagc atctaccagc tagcaagttg ggccagggcg acagtggttc ccatgctggt
    10561 catccgacat catcgtccca tttatgcttt gccaaatgga agatcatctt caaatgaata
    10621 tttggacgag ctttgggtcg atccaaccga caaaatggtc ccctattcgc cttctttgtg
    10681 gtcattatgg aacgatgatc ttacagcatt tggcttcact ctagccgaca atattctgaa
    10741 agccttaggt ggcctgcggt ggttcccttc aagaaaaatt gcacttcgac attgtgtggc
    10801 gtggatcctt gaacgccagg agcccgaagg cgatatcgga ggtatcttcc ctcctctgca
    10861 tgccgcattg tttgctctcg cgctggaagg ttatggcctc gagtctagcc ctgtacgtcg
    10921 aggtattgac gcccttcaaa acacctacgc gtggagagac agcactggtt tgagaataca
    10981 aggctgtatc tcgccaattt tggataccat cctcatgacc atcggcctga ttgactcaag
    11041 ccttccggcc gaaagtcccc tcgttgcacg atcgtcacga taccttaagg cccaccaaca
    11101 gcttggaaac gagggcgatt ggagggtgta taacggaaat gtcccatccg gcgggttcaa
    11161 tttcgagtac tttaattcgt ggtatccgga tattgacgat actgctgcgg caatcttggc
    11221 gatggtgaag caggatccaa acctattaga cttaggcccc atactatctg cagttcaatg
    11281 gatcctggga ttgcagaacg atgacggtgg atgggccgca ttcgaccggg agaacaacta
    11341 cctgttcctc aacaaaatcc ctttcagcga catggacagt ttttgcgacc catccaccgc
    11401 ggatgtgact gggcgtgtca ttgaatgctt tggcctgtta gctaagaggg gttctgtgct
    11461 gtccagaaat ggtaaaaacc caatccctcg gttcttcatc gacgacatgt cctcagctac
    11521 tgagcgtgca atcgactttc tttcaacgga acaagaggcc gatgggtcat ggtacggccg
    11581 ctggggctcg aactacatct atggaactag cgcggtactt tgcggtttgg tctaccactt
    11641 ggaaggctgg gatgatacgt atcccgtcat ggaaaagagg cacaaagtgg acactcatgc
    11701 cgccctggac tggctcaaaa gacaccaaaa tcccgacggt ggctggggcg agcgcctcga
    11761 atcctattat gaacctagtc tcgcaggcaa cgggccatcc acagcatcgc agacggcctg
    11821 ggcattgatg ggcctgcttg catatttagc ccctacagat gagtcaatca cccggggcat
    11881 tcagtacctt tcacggacac aaataaagga gggggaactg gcggggtctt ggaaggagga
    11941 tcactacact ggcactggct ttccaaacca tttctacctt tgctataccc tgtattctca
    12001 atactttcca atgatggcct tgggtcggta taccagtttg tccggttaca gaccactaga
    12061 aaatctggaa agcacagtgg aagaccataa aggcaactct agtgactgtt gatgggtagg
    12121 gtttgaccga cccgatgccc ggtatgttaa atttaatatc aaacttatta gccttcgtag
    12181 caccgtgaaa acttcacaga aactaatccc aggttttgac ctaatggata ttgggaacga
    12241 tgtggtgttt ggcaatcggt cgtgcctggg cacggtggac aggctgggca ggaagcccat
    12301 tgtcatcaaa gatggggcca tgctggggga ccgatctgtg gggcttccga gggtaaacat
    12361 tggaacgcgc acgatggtgg gctcgggtgc attgctgcgg cggaatggct cctatctcga
    12421 tgaccgcagg agctattgcc agcgctggca gatccagcgc accatcgata tcctcatcga
    12481 ggagtctttt ggcgggaggg gcatccctgt cgttaatcag cgggacagcg tacctgagct
    12541 ggttctatcg ggcgatgggg gccaagatcg ggtctgattg tgcgttgagc gccaacgggg
    12601 aaccgcacat atttctcacc gagccggact tggtgacgct gggggatcgg gtgacggtgg
    12661 atgatgccag cctggtatgc catctcaata ccagagggaa ttttgagctg caaagaaaca
    12721 atggctctgt ggggcgtaca ttatggctga gtgggcaggt atacaggtac caatctaaca
    12781 ggaaatgctg aaataatagt aggatttcca cttcagtatc gcccaagtag cagctcttgt
    12841 tcttccagct tttggcagat gtacagccgc ccaaacaaaa gcttcatcct ccttccaatc
    12901 acacaaaaat gcccatagga aagtctcaga tttccccctt cccaacgcac atattgttct
    12961 cagctactac accttggcca tatttaagcc aaggcatgat gcagggaata acaccccttt
    13021 caaaacatcc aaccaggcag aatacgttgc aacacaccac ctgtagcagc cccggggtgc
    13081 ggcagatgtc ccagcggatg gtctgcgcac ttgcgcacat ccgcgagagt gactccttcg
    13141 ggaagatcgg ctgggtcgac tttcattact ccgagggagc cgcactcttc ttcgacactg
    13201 aggtcggtgg atacggcgct ggtggcgtag atggtgagaa ggaggtaggt aaggagtctc
    13261 attttggggt gtctttgttc gaggtttggg tgacaataaa ggtattgatt ttgctgaggg
    13321 tgaaggtggg agaagagaga gtatgtagat tttagttggt tttactagta gtagtctaac
    13381 tgtgtggcgg ccctagggcg aaatttgctg ctgctttaaa tactggcgtg gaaaataaac
    13441 agacaacgtg gcaggactgg ccttgacagt tgcctgctgt ctgtacgacc tattcctttg
    13501 ttccatggtg tattgatagc cgcctggtat tgatgggtcc aagtggatgg atgatgccaa
    13561 tgactcatgg gaatcatggt gattgatttg gtaggtttta acttgaggat ttgatctaca
    13621 gggatacgat tcccgtgaat gaaaccaaca ctcggtgaga cttgattagt tagtctatat
    13681 ctgtctgact acttagtttc tcttggcagg gtccacaaca caacatgaca ttcttataat
    13741 gacaagtaac tcaggacaag cctggcctat tcgcagtggc tgactgaagt caacaatatg
    13801 agagctcagg attcgagcaa ctccctgcaa tgaatgtttg tgacagccgt ggaaggtcgg
    13861 gttcgaagat ctgtgttgat gggtctagaa tacgatcgat tatatgcacc acaccctatg
    13921 tctagtatta ataagaggat agtattcgcc ggtattgcaa ggaaggaatg agttcgtaca
    13981 ctagtaaccg ggatatctga ttccaccaca tttgccactt gattaagaac aatcgcacca
    14041 tcctgcattt gcgatcccac aaagaggtag gtggcagtct aagctagaca tcagttgatt
    14101 acattgtaat cggacgggta ttctcacctg aaaacgctgc aaagtctcat tgaaactact
    14161 cgatgtgagc ctagagttag gcacatagtg gtgtatgatg gtgtttccca gccaccattt
    14221 ccctttccta tgcaggatca gcaacgttga tgcaagatca gaaagattga tctgacatac
    14281 ggagtcggct caaaactatc aaagtatgcc ccggtatata attcaaaggc atcgttgttc
    14341 ggtgcaaaga atgtaaattt ccaatttgga tcggtgtcaa acgcttgtgc aaatccgcca
    14401 agttcatcga ttttctcaga caggatgctt aagtccgacc gagatttgat gaaatccaca
    14461 agagtcgtca cattcaagga gctggaagtg acatagccgg ggatgtttcg gtagttcaga
    14521 ggatcagttg tggctatgac tggactaatc aaagaaagga gtcctataat tggagcgaat
    14581 gagaatatca tattgtgagt ctcgttatct ggataagttg aggtaacaac ttcagcacgc
    14641 gagtcctggg aaaataaaga gatacctcag aggcttcatg atgcaatttg ttcagggtca
    14701 ctagtttggc cgctggatct cccggagcat ctccgcaact tcatccccct gacccggcca
    14761 atgagattat accactcggc tgaaaggctg cagccttatt agctagtatc tttactctac
    14821 ctagcccctt tactccggtg gggattccgg acaagctccg gaggttgcat agaaaagatc
    14881 tgctgcagtt gatctcttat aactacccca aaaatggctt cccggttact gcacatcacg
    14941 tacccttggg caaacccggc aacatgatga aacgcaaatc tcagctgtca tcattcacct
    15001 tagtgacggc ggcaatttta ccttttgccc atcttgtgat gggaggcaca agtctcgcac
    15061 aaaagcctca gatgggctgg aactcatgga acgcattcaa agcgacggtc aactatacga
    15121 tagttcaaga agttatttcg ctgttcgata cgcttgggct gaaagaggcg ggctacgagt
    15181 acgtgctgct tgatgatgga tgggcaagtt acaatcgcac gtccgacggg tatcttcaag
    15241 ccaatgcaac atcctttcct cagggtatta aggcactggc gcaagaggtg cacggtaagg
    15301 gcctaaaact aggcctttat ggagatagtg gtcattacac ctgtgcgtgg agaccgggaa
    15361 gctggggata cgaagagcga gacgctcaaa cgttcgcggg ctggggcgtc gactacctca
    15421 agtacgacaa ttgtggcgga tttcagtcga tgacagaggc ccctcagata cgctttgggg
    15481 caatgaagaa tgctctcacg ctttcgggtc gagatatctt ctattccgtg tgtggatggg
    15541 gttatcagtt tccctggcac tggggaggag gtgagataca ccctgcaaac caaccaatct
    15601 tctaccttaa gatactcatt ccacccgcct gcagatattg gtcactcata cagaatgtct
    15661 ggtgacatta caacaagctt caccaacgaa actgagtgcc agtgcaagac cgcctactgt
    15721 ctcaataccg ggtatgccgg ttgctcagta ctgaccatca tcaacaaaat gaaagaaatc
    15781 agccaatatc agacgccagg tcattggttg gatatggaca tgctagaagt cggaaatgca
    15841 aatttcacac tcaaccagca gcagacgcac tttgcattct gggcggcgct gaagtctccc
    15901 ttgatcattg gtgctgatct cagcaagctt tccaatgaca gtttagctgt tctcaccaac
    15961 aaggctatca tttcgatcaa tcaagacgcg ctgggggagc ctgtgacgta tcgcgaagca
    16021 catagcaaag aaggtctctt ccaggtatgg gctgggaagg ttgaggacgg atatgttgtt
    16081 ctgctgctga atgagaaaag ctatccgcaa actgtgtctc tgagctttgc cagtttggga
    16141 cttggctcac ctcagaaggt cactgaactt tggtcggggc agactttgca ggatcttagt
    16201 aagttcaatg ggactttggg gtcttatcaa actcttgttt tcaaagtgaa ggcatgaaaa
    16261 actgaggcat ggtgtggctt taaactgtca accttcatct tcataacata ttttcttatt
    16321 atattcgctg gaagagtctg tagatttctg caaacccaca aagtagacaa atagacatat
    16381 tgaatataaa gtaggcttga ttatgtctca aggctgaaat tacgctcgat tgtcttctaa
    16441 ttgcccgccg tattcccaaa taagacaagt ttgaggacgg caaatcccag taaccacaat
    16501 tgttaaatta ggtgaaaagc atgagccttt gagcagagat ataccactac atcccattgt
    16561 gatctttcta taagaaattc gtacacattg cttgtgccaa ccgcccaata tggaagtagt
    16621 tggaaggaaa aataggcctt gaagaaatac ataccggcat atgccaagct ccgtcctcat
    16681 tgtttagcgc gtaacgcttc cgcgaacata tcaatcgggg gtgacggagg tgaggatgtt
    16741 ccatctcatg tccctgcagt ctcggctgat agtggcaaca gttcattcca caaccctcgt
    16801 gtcgagggag tggcatgttg gtaagtggta tcccaagctt ctttggctgg cccctgaaat
    16861 gttaagttga tgctaaattt tggttcttac ttcttgtctc tgacaggtgg actgattggt
    16921 gggtcgacgg gttgcgtggc tcactggatc ccgtgcacta gggttcgaca actgcctccc
    16981 ttttcgtccg ccacacatta actaccctgc ctggactccg tagataggga taaagtactc
    17041 atgatcaaat gaattgcagg tttctcatga cgcactctct cacgcggaga gagtctttag
    17101 tgctcctgcg catacgtaag ttcgccgccg atccttccct gaagacatgg accctggata
    17161 ttaactgcag gtgggtctgt cttgcactcc gcaggaaata ttttctccta tttcctgtac
    17221 atatcggtgg aaccaaaccc tagaacttta aaagaacgga aacgatagtc taataagaat
    17281 ccggtgctat tcgagaatct atacgcgcga tagtgaaggg cattttctgt acggttaggg
    17341 ccagcgcgcc ccaaatctta atgaagactc aatagtagcg acgagcctct gcgtggactg
    17401 acaagcggaa gttcctggcc attatctatt taattatgtc gatccattgc ctattcgact
    17461 ttcaattaag catatcgaac cacttgctaa gtcattctgg gaaaatctcc ggcgtcggac
    17521 actcgccggc aattaccccg cccgccgaca ggaagctgat tggcgcagcg tatgtctcca
    17581 tgtctacgaa ctcaacggtg cagaggatgt gccaggagtg gcatgacaag tgcagattgc
    17641 ggggaagaca attcccccat gggggcgtcg gtctttgtgc atgcctgact ctgtatgtca
    17701 gacatctcct tcctggagac aatgttcaca tggtaaatct ctcaataatc tcaactctgc
    17761 ctacccgatg ccccccaaat cccatcccgc aacagccaac gccaacgtag gagacttgcc
    17821 agagacaacc aacaaaggag aggaggagat tccagcctgt cagttctgtc gcaagaaaaa
    17881 agccaagtgc aatcgagcgc agccgtgttc gcaatgtatg cgatcggatg ttctttgcgt
    17941 ctacgatgat cgacggacga agcccggtct ccgagctggg gcggtcgacc agctctatcg
    18001 gcgcgtcgag acgctggaga atatgttttt gggtcaggag atgctctggc agcagatgtg
    18061 gaaggcttta ttcccgaaca ctgagccccc gcgatccctg gacaagggaa ccacggcagc
    18121 cacgaccctg acggagcgtc gggagcagtt gaaggcttca ttacaggagc ctccaccctt
    18181 agcagcgaag aggtcactta cagtggcaga cgccgacaat tctgcaccgc tggactgtgt
    18241 tcctctccca gccaaacgcg cccgtgtgga ggacgaagtg gctccccatg cggctgtcct
    18301 agagcccgag cctttcttgg ccaactcttt acctgacatc gtcttgaacg aactggtgga
    18361 tttctacttt gtcaacatcc atccgtggat accgatacta cacgttaaga gattccgtga
    18421 gcgcatgcga tcgccggagg aacgagggca tatcaattgc atcttacatg ccatcatctc
    18481 tgtctgtgcc cgcttttcac aaaatggccc aaatggcgat acgttgaact taaaagagat
    18541 cgccaagaaa agtcggcaag aggtaatatt gcaaagcact gaaaccttct ccgttgagaa
    18601 tctccaagcg ctagtgatcg tcgcatttga gacagtgagc aagaggccca cgccatggat
    18661 atccgggaac aagtagactg atttcattcg aacagattaa tcgcggccgt gggccctcct
    18721 catggtctat cattggcagc atggcgggaa ccgtggagca gcttcagctt ggcgtggaag
    18781 aagatgacct gtatcgtgtc aagcgcatgg gagaaagact gatcaggcgc atggtttttc
    18841 tgacaccatc tcggtcatgg agtgaagcag aagagcgtcg ccgtgtattc tgggcagtct
    18901 ttctcatgga ccgcttctgc agtgtctcga caggctggaa gatcagtctg aggaatgctg
    18961 atgtgaagcg ccgtctcccg tgtgaaggtg ctctgtggga aaaggaacaa gaggtctgca
    19021 ccccgtattt cggcatctct gatttcaaga acacttccat gcctaatagt cactcaactt
    19081 cgatggatgg ctctgaagaa caggccatcg gcgcatttgc ctacatcatc gaggctactg
    19141 agtcactggc cttagtgacc aacttctatc tccaccacgt ctttctgatt aacgatgcca
    19201 gcaaggcacg attatggctc gtcaaattca aggaactaga tctgcgactg attcagtacg
    19261 tatcatctct tcccaaggga tgtctaaaca ccagtgatgc tgacgcgcgc agatggaaaa
    19321 tccatttgcc tcccaaatgg cgcgaagcct gcgtcctaaa tgaacacaga gtcatggacc
    19381 ccaatctgac tctggcacac atcacccaca atacggcggt aattctgctg catcagggca
    19441 tcgcctatcc accatcgcat tggcagtact gtcccattaa gctcccatca gcatcctctg
    19501 ctgatacgtg ccttgaagcg gcttcagaga tagcaactat tgctaataaa ttcctgtcct
    19561 tttctcccat cttcacgaat ccccaatttt ctttttgtct attcatcgcc ggccgcacac
    19621 tcctcgcaca cgctaggtac aatagggtac cgccttcacc cgcactcaac accctcattg
    19681 caaacctgat ggagatctcg cagcggtgga caagacacca tgacgccagc gaatcccagc
    19741 aagaggagag cctggcattc aagtttgcca cccggctcat cgaagcccag cagaatcgaa
    19801 ccagtgcatc tcgtccgagt ctggatattc gcacgactgc gtattcagat gaatcaaaag
    19861 aggagatgta caaagacccc atgagaacaa accaggatga tctcccagac tatgaatcgc
    19921 ttagcagacc actgcagctg gcttcattcc cttcgcagga gtccacttcc tgcacgttcg
    19981 acccattcag tctggccttc ccaccgctgc caccagcctt tcagcaggat ttttcgccca
    20041 ctggtctcga cccgctctct ttctataata tgcaattgcc gtcggagtct atgtcttcgc
    20101 ctcttggtac gagaagccac ggatcgggtt ctcagcacga ttcggagagt tccatgacca
    20161 gtctcttgcc gacggatatt tctcatctct tcgatatgac gtctagtccg gggcagagaa
    20221 tcagttatta cggcaataca cggggagtga ccaacaattc gatagtcgag ggagccgaca
    20281 attagacgag taacagaact tgcgtgatca tatttcctct catttacgtt gtgcctctat
    20341 attttatgtc tacttccctg cccctcagag ggggttcttt aatgcttcta ctccctgcca
    20401 cactcgctgc cttatatatg aggatcgacc aagtccatct caaggagcat atttccaaac
    20461 agcaagaaat aataatcagc atagacgaga ccatggtccg accaccttcg cggagcaaac
    20521 tcatagttat tgattgttgc gcccgtcagt atagtttcag caacatcccc aaccaccctc
    20581 agcacttccg ccccgttccg agtctcagtg tgatgcgtcg agcactggtc tgcgtacacg
    20641 gagatttctg acgcaggacc agcctcgaac cgcatagggg gattcaaata ccccacaacc
    20701 gtacaatcaa ccagcttcat agcagcccga aggtagtggt tagccgcctc aacatcatgc
    20761 atcttcttgt aagccttata gagcaacaac atcccacagg cagcgatcat cgcagcagag
    20821 gtatcgcgtg gggaggtgtc agtaacaggc gcatcaaaat cccaatatgg gacgccatca
    20881 tccggcaatc tcgcaagaaa tacatccgcc agtgctctag cagtgcgaag gaatctcatc
    20941 tctcttgtcc actcgaatgt ctgcgcgaac cccatgattc cccacgcctg gcctcgtgcc
    21001 cagcagctat catcactata tccctgattt gtgaattttt tcttcacctc ccccgtctcc
    21061 aggtccagat caacaacgtg aaatgtcgta tagtcatctc ggatatgatg cttctgtgta
    21121 gtgatcgcat gagccctggc tatatcataa agcctccgac agcctgtttc tctcgctgcc
    21181 cagaaaagca aatccaggtt cagcatgttg tcgatgataa ataggaagtc ctgcgacgaa
    21241 tttctgtatg catagcgctt ggtgatgcac tggtcccagc tacgaataca ctgggttgat
    21301 tcattaaagc gactggcgag ggagtgggct gctagtatga gagtgttgta ggctgctggg
    21361 tctcgatgca gggtccatgc tttcatcgcc caaggggtga tcatgaaccc taggtcgtga
    21421 gtatccttgc gaagggcgtt ttggtgaagg tttgctgtcc accagcggca gaggtgctcg
    21481 tgttggaggg gatgggggtg gaggatggat tcgctggttt gtcgttggag aataagatgc
    21541 cggtcgcgga agagagtgct gcgttctaag aggaggtata aagagcctgg gaagaagccg
    21601 gaggtccaga agtcaagggt tcggtagata tatgtggtct tgtcttcgcc ggtatattcg
    21661 gggtagaagg ttggaggggt tgtctatgta gaatgtattt tgtttaggat agtgtgaaac
    21721 atttagcggt tcggcgaaat aactcacact acccatcgcc ttggatgcga cgaaccagac
    21781 cttggctagg agggattctg agaagagggc ttcgagtact cgcgcccatt gcttggtagg
    21841 gagtacttcg gtgccgttga tggttgttgg gggtcccgct tcgatagaca tcgttcctag
    21901 tcaatatatg gtttgcacgc tatagagagg aagacttcaa gataaactga atgagatgca
    21961 agatacaagg ttgaaagtgt gttcaagacc gtccatctac aagatctcct gctccatttg
    22021 aggctgtatg cattagccct cggaaggggg tccgggaatt cctccgcgcg agaactccct
    22081 gctaaaatgc actggacagg catttcgggc ta
//
