LOCUS       ch4                    21742 bp    DNA     linear   PLN 26-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   ch4
VERSION     ch4
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-03 01:15:18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 150540
            Orig. end    :: 172282
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21742
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[160428:160451](+),
                     [160513:160613](+), [160672:161025](+), [161076:161247](+),
                     [161298:161583](+), [161630:162435](+)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(9889..9911,9974..10073,10133..10485,10537..10707,
                     10759..11043,11091..11895)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..21742
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21742
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            complement(join(1..169,221..379,434..614,659..845,
                     892..1780,1840..1907,1977..2009))
                     /locus_tag="KYF_004308"
                     /product="hypothetical protein"
     gene            complement(1..2009)
                     /locus_tag="KYF_004308"
     CDS             complement(join(1..169,221..379,434..614,659..845,
                     892..1780,1840..1907,1977..2009))
                     /codon_start=1
                     /db_xref="InterPro:IPR007219"
                     /db_xref="PFAM:PF04082"
                     /locus_tag="KYF_004308"
                     /note="EggNog:ENOG41; antiSMASH:Cluster_29; GO_component:
                     GO:0005634 - nucleus [Evidence IEA]; GO_function:
                     GO:0008270 - zinc ion binding [Evidence IEA]; GO_function:
                     GO:0003677 - DNA binding [Evidence IEA]; GO_process:
                     GO:0006351 - transcription, DNA-templated [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_004308-T1"
                     /transl_table=1
                     /translation="MSSQESSGHRQMRPCQNCLALNVPCEIGVSKRGKYPRKKSARQQT
                     DGNSVQLPASSAKGGNHSFTVSAGDKSDAKESHVHPIPGDAASAHPTVFFGESSPLTVV
                     IDEGRRSPEKGTNEMHMTRFHYAIPEKLDAFNTRDEAFRAHKIKQEGQLRADGAFSYPP
                     PETCETLLRAYFDWFHPCFPILDCAAVYESYVQGSMSPLLLQAILFIGVSLCTDEVFAR
                     TEFSVRYWAKFLFYSRAKAIYDAEWESNKTVKIQALFLLSFWRGGPSEERDIRFWLGIA
                     IDLAQKRGMHLMYVFFCLTLSPVNSVRSKFPFASRREAGLWKRIWWSLYTRDQQSAAAL
                     GLPPHIRDEDCDVDMLEPEDIREEAVGGQSHFGVQCIEDLSYPAEMAKLAKLLRSIVST
                     QYSPLGPSSNGASRAALHQQLRDWEANMPLELKLENATTPRAKFLAGLLHMTYQNLYIL
                     LYRPSFLHPPDGDLDSQGQIALNAATKSTRVLEDMLSHNLVQHGSSHLIIHVFLTLCIH
                     TIHFRRTSGTGRKLAEHRARLCLLSLQELQKSWDLENWVLNLFF"
     mRNA            complement(2480..3733)
                     /locus_tag="KYF_004309"
                     /product="hypothetical protein"
     gene            complement(2480..3733)
                     /locus_tag="KYF_004309"
     CDS             complement(2480..3733)
                     /codon_start=1
                     /db_xref="InterPro:IPR003673"
                     /db_xref="InterPro:IPR023606"
                     /db_xref="PFAM:PF02515"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189:L-carnitine dehydratase/bile acid-inducible
                     (Score: 346.4; E-value: 3.1e-105)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="KYF_004309"
                     /note="EggNog:ENOG41; antiSMASH:Cluster_29; GO_function:
                     GO:0008410 - CoA-transferase activity [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_004309-T1"
                     /transl_table=1
                     /translation="MPNTRPLVRAACHNLSGMRHASTSATKKAGPLAGITVVSLEQAIA
                     APFCTRQLADLGARVIKVERPGVGDFARNYDTRVNGLASHFVWTNRSKESLALDLKKPS
                     DHSVLMRLLGRADVLVQNLAPGASARLGLSYDDLKAAHPSLIVCNISGYGPDGPYRDKK
                     AYDLLIQSEAGMLSVTGTGKEPAKVGISIADISAGSYAYSNILAALYQRERDPSKRGCN
                     IDISMLESMVEWMGFPMYYTYENAPGPTPAGASHAAIYPYGPFETGDGTVMLGIQNERE
                     WAKFCDIVLGQPSLATNERFVNNSLRSQNRDELKKIICDVFSSLSAEQVIARLDAAAIA
                     NASVNDMQGVWNHPQLKARQRWTDVKTPAGSVPALLPPGMTMGDEDTYGARMDAVPDVG
                     EHNKAILAELGLDEGTEK"
     mRNA            join(5872..5996,6051..6789)
                     /locus_tag="KYF_004310"
                     /product="hypothetical protein"
     gene            5872..6789
                     /locus_tag="KYF_004310"
     CDS             join(5872..5996,6051..6789)
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1137:Major
                     facilitator superfamily MFS 1 (Score: 215.5; E-value:
                     1.6e-65)"
                     /gene_kind="transport"
                     /locus_tag="KYF_004310"
                     /note="EggNog:ENOG41; antiSMASH:Cluster_29; GO_component:
                     GO:0005887 - integral component of plasma membrane
                     [Evidence IEA]; GO_process: GO:0055085 - transmembrane
                     transport [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_004310-T1"
                     /transl_table=1
                     /translation="MSEPKNQPVEEPTIPPEEGVKGWLTVAGSFCALFSSFGFLNAIGV
                     FQTTYQQTSLKDYDASDISWIFAVQLALMWAPGPLWGRMIDTYGPIPVLWPCSILCVLG
                     LCMTSLAHEYYQIFLAQGLCFGIGAGGVFTSAMICVGQWFVRRRGLATGIAVSGSSLGG
                     VIFPIFLDRVINDIGFYGAVRYTALFVGIMLAIACLLIRSRLPRKEWNGKAAWVDLTLL
                     KDTAFGLYTAGAFFIMFVIRSYQWPYPSTDSDRWGLWAPFDYISSMAENAGFSSTLALY
                     LISIIK"
     mRNA            join(7854..8656,8706..8931,8988..9191)
                     /locus_tag="KYF_004311"
                     /product="hypothetical protein"
     gene            7854..9191
                     /locus_tag="KYF_004311"
     CDS             join(7854..8656,8706..8931,8988..9191)
                     /codon_start=1
                     /db_xref="InterPro:IPR001663"
                     /db_xref="InterPro:IPR015879"
                     /db_xref="InterPro:IPR015881"
                     /db_xref="InterPro:IPR017941"
                     /db_xref="InterPro:IPR036922"
                     /db_xref="PFAM:PF00355"
                     /locus_tag="KYF_004311"
                     /note="EggNog:ENOG41; antiSMASH:Cluster_29; GO_function:
                     GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence
                     IEA]; GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]; GO_function: GO:0005506 - iron ion binding
                     [Evidence IEA]; GO_process: GO:0044237 - cellular metabolic
                     process [Evidence IEA]; GO_process: GO:0055114 -
                     oxidation-reduction process [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_004311-T1"
                     /transl_table=1
                     /translation="MWRLLGRSSNTSEKSSPPRSLPGSWYRSDAMYQLERRAIFSKRWM
                     LLTHSSRLTKPGDFLSFTISNFSFFLTRDREGSINGFHNICRHRAYPVVQARSGATSIL
                     SCKYHGWSYGLKGNLSKAPRFETVSNFDKSQHGLLPIHVHIDKAGFVWVNLEAGDPEVK
                     WEDDFQKIDEQPRMQDFDFDGEYTFDHYWEMDVEANWKLLIENYNECYHCATSHPLING
                     VSDLPRYRVEPKARYMEHHIFNKDNIDAQFRRSITYFYPTTSVTVTDKFFYIQRMIPVS
                     ATMSKIENEVYRHRDATDEEFANINAFYRQVLDEDRDLCVGAQENLSAGVFINGELHPD
                     KEKGPIHFQDHVKTMVMEHRRKEEEQGGEEIWPAVPKVTGEMRTGKLAEEERFCSQLEA
                     ASCMARSELAW"
     mRNA            join(9889..9911,9974..10073,10133..10485,10537..10707,
                     10759..11043,11091..11895)
                     /locus_tag="KYF_004312"
                     /product="terpene cyclase"
     gene            9889..11895
                     /locus_tag="KYF_004312"
     CDS             join(9889..9911,9974..10073,10133..10485,10537..10707,
                     10759..11043,11091..11895)
                     /codon_start=1
                     /db_xref="InterPro:IPR002060"
                     /db_xref="InterPro:IPR008949"
                     /db_xref="InterPro:IPR017825"
                     /db_xref="InterPro:IPR019845"
                     /db_xref="PFAM:PF00494"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="KYF_004312"
                     /note="antiSMASH:Cluster_29; GO_function: GO:0016872 -
                     intramolecular lyase activity [Evidence IEA]; GO_function:
                     GO:0016740 - transferase activity [Evidence IEA];
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]; GO_process: GO:0009058 - biosynthetic
                     process [Evidence IEA]"
                     /product="terpene cyclase"
                     /protein_id="ncbi_KYF_004312-T1"
                     /sec_met_domain="phytoene_synt (E-value: 3.3e-20, bitscore:
                     69.3, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MGLDYVILHCTYTIPAASALTVLYYPFFTAQDRCKICILITIAIL
                     ATLPWDSYLIRSAIWTYPPDAVVGLKILDIPIEEVFFFAIQTYITSLTYCIFTKPLVRP
                     MYLRSHLERRGTRYVVATVILALMGGGTACLLLGRRMTYLGLILVWACPILLFQWMMSY
                     PFLSELPWKPTITSICLPTLHLWFADSRAMGTGTWRIEEGTKLNFRIGGLELEEALFFL
                     VSNMMVVLGLVGCDYAYALQEYESLSQPASDVYITLRKALSLLARPLPIDASLISALSQ
                     AVYRLQEKSQSMFLGSALFQGQLRIDLIFLYSFCRVMDDLIDEAEDEQEARFWVTECRH
                     LLDSTHRSEPHSDHFYTGKKGEEHERLRQSISYLPPSHLSNDSFDDLLKGFEIDLKFNP
                     QREAFPIQSEYCLDQYAGFVAGTVGVLVFDLTLFHCGHYFIQDVPRLRRAAKDMGKAMQ
                     CINIARDIHRDAAIGRVYIPTTWLGEVGLTPGDVLQCPNSPVTYDLQERMLQKADEYYQ
                     VSRGAMEELPRGVREPLRATVASYMDIGLLLRERKGTSLAQASKMKVPLVRRLKVGWLA
                     ML"
     mRNA            join(12565..12696,12749..13675)
                     /locus_tag="KYF_004313"
                     /product="hypothetical protein"
     gene            12565..13675
                     /locus_tag="KYF_004313"
     CDS             join(12565..12696,12749..13675)
                     /codon_start=1
                     /db_xref="InterPro:IPR000537"
                     /db_xref="PFAM:PF01040"
                     /locus_tag="KYF_004313"
                     /note="EggNog:ENOG41; antiSMASH:Cluster_29; GO_component:
                     GO:0016021 - integral component of membrane [Evidence IEA];
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_004313-T1"
                     /transl_table=1
                     /translation="MQRKLELVDFTCFYEFCTYLLGAAGALLESDVVKTRPNNTRAYKE
                     EWSWKDLVLTIWLFTADDFTTFVIPETAFGICAALSGPLLTDDNTPDLLSVVSRISIVM
                     LWNWLNLFVFNLANQRHPDSVAEDKINRPWRPLPAGRISILQTRRLLLLAIPMVLASSV
                     YLGAWEETALLYTLNWVYNDLSGGDDGFILRNVLLALAFSQYNKGSLRVATGTGFDILP
                     RAWRWIWVTSAVIGTTMHIQDIKDVEGDRAKNRRTMPIVMGDGPARWSVAVPVAIWSVV
                     CPAFWELDVARYVLPVAVGMTIAGRILLLREKAADKRTWKMWTAWTAVIWVLPLFKNAS
                     VFVRFGKKLGVV"
     tRNA            13881..13951
                     /locus_tag="KYF_004314"
                     /product="tRNA-Gly"
     gene            13881..13951
                     /locus_tag="KYF_004314"
     mRNA            complement(join(14522..15708,15761..15960,16014..16144))
                     /locus_tag="KYF_004315"
                     /product="hypothetical protein"
     gene            complement(14522..16144)
                     /locus_tag="KYF_004315"
     CDS             complement(join(14522..15708,15761..15960,16014..16144))
                     /codon_start=1
                     /db_xref="InterPro:IPR015590"
                     /db_xref="InterPro:IPR016161"
                     /db_xref="InterPro:IPR016162"
                     /db_xref="InterPro:IPR016163"
                     /db_xref="InterPro:IPR029510"
                     /db_xref="PFAM:PF00171"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 505.1; E-value:
                     2.4e-153)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="KYF_004315"
                     /note="antiSMASH:Cluster_29; GO_function: GO:0016491 -
                     oxidoreductase activity [Evidence IEA]; GO_function:
                     GO:0016620 - oxidoreductase activity, acting on the
                     aldehyde or oxo group of donors, NAD or NADP as acceptor
                     [Evidence IEA]; GO_process: GO:0055114 -
                     oxidation-reduction process [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_004315-T1"
                     /transl_table=1
                     /translation="MADSLFVDITTPNGRQYQQPTGLFINNEFRPSSSGQTIVSLDPAT
                     DKPIATVHAATAEDVDAAVQAAKAALSHPSWKLLPATERGQLMGRLADLMEENRALFAA
                     IDAWDNGKPYHVALTEDLTEAITTIRYYSGWADKTFGQTISTTPQKFAYTIRQPIGVVG
                     QIIPWNYPLSMATWKLGPALACGNTVVIKAAEQTPLSILVLATLIKKAGFPPGVVNVIN
                     GYGKEAGAALVQHPLVDKIAFTGSTATAREIIKMAAGTLKNITLETGGKSPLIVFPDAD
                     LEQAVKWSHFGIMSNKGEICTATSRIFVHRSILASFLEKFKKEIETTSKIGDQWDENTY
                     QGPQVTRAQYERVLSYIETAKKEGATLVTGGKAYTPKDEKNAKGYFVEPTVFTDVTDDM
                     RICQEEVFGPVVVILPFDSEEESVRRANDTTYGLGAAVFTTDLERAHRVAADIEAGMVW
                     INSSQDCDPRVPFGGVKQSGIGRELGEAGLEAYSQVKAVHVNMGSRL"
     mRNA            16747..17667
                     /locus_tag="KYF_004316"
                     /product="hypothetical protein"
     gene            16747..17667
                     /locus_tag="KYF_004316"
     CDS             16747..17667
                     /codon_start=1
                     /db_xref="InterPro:IPR002220"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="InterPro:IPR020624"
                     /db_xref="PFAM:PF00701"
                     /locus_tag="KYF_004316"
                     /note="EggNog:ENOG41; antiSMASH:Cluster_29; GO_function:
                     GO:0016829 - lyase activity [Evidence IEA]; GO_function:
                     GO:0003824 - catalytic activity [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_004316-T1"
                     /transl_table=1
                     /translation="MTVTQQTPALHGIMVALITPFTDDKTQIDAARLKSHIDHLIGAGV
                     HGLVPGGSTGEFTTMTREERKQLTELCVEYAAGRVPVVAGTGSTSTEEAVDLARHAAQA
                     GAAAVMVVPPFYDPLNVEQLTELMSEIHEASQLPIVYYNIPSASGLTLTPQQIADLSKV
                     GVKYLKDTSGNAPAYTELVFGLSDQITAFNGWDTLTFYGLAAGSPGAVWGAANIIPELA
                     VELWNAVSVEGDLKKGRELWAKAWPICKFLESHNYAAAVKTGVELRGQATGGLRKPFAL
                     LKDDLQSELAQLMVNANVNVVKRSS"
     mRNA            complement(join(17756..18799,18849..19801,19877..20138))
                     /locus_tag="KYF_004317"
                     /product="hypothetical protein"
     gene            complement(17756..20138)
                     /locus_tag="KYF_004317"
     CDS             complement(join(17756..18799,18849..19801,19877..20138))
                     /codon_start=1
                     /db_xref="InterPro:IPR001138"
                     /db_xref="InterPro:IPR021858"
                     /db_xref="InterPro:IPR036864"
                     /db_xref="PFAM:PF00172"
                     /db_xref="PFAM:PF11951"
                     /locus_tag="KYF_004317"
                     /note="antiSMASH:Cluster_29; GO_component: GO:0005634 -
                     nucleus [Evidence IEA]; GO_function: GO:0000981 -
                     DNA-binding transcription factor activity, RNA polymerase
                     II-specific [Evidence IEA]; GO_function: GO:0008270 - zinc
                     ion binding [Evidence IEA]; GO_process: GO:0006355 -
                     regulation of transcription, DNA-templated [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_004317-T1"
                     /transl_table=1
                     /translation="MTSSKQSGRRTRRSHALGACRTCRRRHAKCDQKRPTCQMCRATGV
                     VCEGFVDEIRWMSDRKSQPSSGTTAKKANDPEKQGPRRHLYTEKSRVSMSDALSADLVS
                     GSIDASLAEIETRSRDTERPSQGDIVVGPFAVLDFSLTEPKSASRAHPTDETTVANDVI
                     LPSGDTLAEGASGVSPALSQESIAYMNDLLQWSDILSLDPQLQSATLSGTFDLGDWLPL
                     DLGTQAPMLEHNLLGEAPSLMDDTAALYHCVPGQDNASKMVPPVDSNPPDVLADAHYLL
                     RHFQDHVISRMMAVPLDQKSPWKILNVPSAVVTYSDITFLGSQNITHARLANLYCLLAC
                     SALHLTVNPSMRTSDSTERWKPVAEYAYHLAKDHMQMSLKHETQEPKKAKYKDQLMAIC
                     ALTEFAILSSQQQDARCYMIDAERLLRLRGLPKQRISQKARLLHHTYTWLRIVGESTYA
                     LHNYTPSDAFMEALKYRFRYQKVENTQAAGYRTSRLDDFLRLDRRPSDSDLDIDEPKED
                     DVGLYDIHLQDSRKYPATLYSQIYGVSETWLSLVSQTTRLANVMETFRVAREMRQGNNA
                     SLEAWEALHRRSARLESMVCTFASRRTEDNICDSTNILAKSHGCLLQALNSALVIFFYR
                     RIRQVHPAILESQVDKVISSLNEFDVALVEADHTGPGTVWPLFIAGCEATTPERRQSIT
                     LLLDKGEARCGFSAYHTVRDVMNQVWDKQDAHFTRSRGETFPTWLDVVKSKQIWPILA"
     mRNA            complement(join(20498..20755,20816..21279,21332..21409,
                     21468..21673,21726..21742))
                     /locus_tag="KYF_004318"
                     /product="hypothetical protein"
     gene            complement(20498..21742)
                     /locus_tag="KYF_004318"
     CDS             complement(join(20498..20755,20816..21279,21332..21409,
                     21468..21673,21726..21742))
                     /codon_start=1
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF13460"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 34.2;
                     E-value: 3e-10)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="KYF_004318"
                     /note="EggNog:ENOG41; antiSMASH:Cluster_29"
                     /product="hypothetical protein"
                     /protein_id="ncbi_KYF_004318-T1"
                     /transl_table=1
                     /translation="MAKIFLTGASGYIGGDVLHALKSALPTCQYTVLLRDEAKAQKLSQ
                     AYPDVQVVLGDLDASSTLEQQAREADIVIHTASSNHVKSAEAIARGLTAPERPKPGHWL
                     QISGASVLSIPDIVASAFGGPSNKIYSDVDGADELRELIRQYSAKRVVDNLVLSLPHTS
                     SRPKTALIFPPIIYGRGRGPINQRSIQIPELARVTMQRRGGVQVGRGEATWSNVHISDV
                     SNIFVKLAEKALQSEEGKLWNENGLYFPGSRAISFGSISARVAQEVKKLGLAESESVTE
                     ISHEEADSLTPHGGVLWGTNAQQVAQRAAKYLKWVPEGRTLEEEIPHTVLAEAQRLGLK
                     "
ORIGIN
        1 tcagaagaac aggtttagta cccagttctc caagtcccaa gatttttgca gctcttgtag
       61 gctcaagaga cagagccggg ctcggtgttc cgccaattta cgacctgtcc cggacgtgcg
      121 acggaaatga atggtgtgga tgcagagggt taaaaacacg tgtatgattc tacatggtca
      181 gcttgaatcc tctatagcat atcggcgggg acggtcttac agatgagaag agccgtgttg
      241 gaccaagtta tgcgaaagca tatcctccaa cactcgtgta cttttcgtcg cggcattcaa
      301 ggctatctga ccttgactat ccagatctcc atcaggaggg tgaagaaagg acggtcggta
      361 aagcaggatg tagagatttc taatggcatt caatcagtga aatacactca agtacccaat
      421 acatgccacc tactggtatg tcatatgtaa gagtccggcc agaaacttgg ctcgtggagt
      481 tgtggcattt tccagcttca gctcaagagg catattggct tcccagtccc tcagttgctg
      541 gtgcaatgcc gctcgtgacg caccgttaga tgacggaccc agcggcgagt actgggtcga
      601 gacaatagaa cgcactgaac agtgagcaaa gattcgcagt atggaggttc ggacatacat
      661 aatttggcta actttgccat ttcggctgga taagagaggt cttcgataca ctgcacccca
      721 aaatgacttt ggccgcccac agcctcctct cggatatcct caggctctag catgtcgaca
      781 tcgcagtctt cgtcccgaat gtgtggcgga agcccaagtg ctgcggcgct ttgctggtct
      841 cgggtctagc aacggtcagc atctacatca ggcttacgag aggtgacata cgtaaagcga
      901 ccaccaaatc cgcttccata gacctgcctc tcgacgggag gcaaacggga atttggacct
      961 gactgagtta acaggagaca gggtaagaca aaagaataca tacatcaaat gcatgccgcg
     1021 cttttgtgcc aggtcaatgg caatgccaag ccagaatcga atgtcccgct cctcagatgg
     1081 tcctccacgc cagaagctca acaaaaacag cgcttgaatc ttgaccgtct tgttagactc
     1141 ccattcagca tcgtagattg cctttgctcg gctgtaaaag agaaacttgg cccagtaccg
     1201 aacagaaaac tccgtccggg caaacacctc atccgtgcaa aggctgacgc ctatgaacag
     1261 tatcgcctgg agtaagaggg gcgacatgct cccctgcaca tagctctcat acaccgcagc
     1321 acaatcaagg attgggaaac aggggtgaaa ccagtcaaag tacgcccgca gaagagtttc
     1381 gcatgtctct ggcggcgggt acgagaaggc cccatcagct ctcagctggc cttcctgctt
     1441 gatcttgtgt gctcggaaag cctcatcacg ggtgttgaag gcatcaagtt tctcaggaat
     1501 ggcataatga aagcgagtca tatgcatctc attagttccc ttttcaggcg accggcgccc
     1561 ttcgtcaatc actacagtga gtggactcga ttcaccaaag aacactgttg gatgcgcact
     1621 cgcagcatcc cctggtatcg ggtgaacatg cgactctttt gcgtcggatt tatcacctgc
     1681 tgacacggtg aatgaatggt tccctccctt cgcagatgat gccggcaatt ggaccgagtt
     1741 gccgtcggtt tgttgccgag cactcttctt acggggatac ctaagccatt gaatcagtct
     1801 acgccaaact accataatga cgaaaccgtg aaaacatact ttcctcgctt tgaaacgcct
     1861 atctcacagg gtacattcaa tgccagacaa ttctggcatg ggcgcatctg tagcacattg
     1921 cagcggattc gccgcttatt gcagtggaga caagcctgct tggccctggt tcttacctgt
     1981 cggtggcccg atgactcctg actggacatg atcctcgaat tagctccaat taccaatgaa
     2041 agagatcgtc cacagtggag ttcagaggtg gccaggcaga atgcaagtag ccgtagtcga
     2101 ggataaagcg gctttatgct gcctcggtct tggcgggcat gtcggctttt tgcctgtttt
     2161 cccgatccac ttgcttcggc gatgggtata ttgcgccgat attcacttta cgctggatac
     2221 cgtcgcgggg tgatattagg ggcagcaggg gtaggttgcc tgaattggat taaactgtaa
     2281 gatccatatt gtggtcgact agttctacgt ctgaacatcc tttgacatgc aggtatcttc
     2341 aacctcgtga gtggacagta gaattgcccg aggtgaatcc atcgcactga gttatttaca
     2401 aagggcctaa aagttccaat actcgcaagg atagccaagt ccactagctc aactgtacat
     2461 gtcattaatt caactgcagc tatttctccg taccctcgtc gagccccaac tcggccagaa
     2521 tagccttgtt atgctcaccc acatcaggga cagcgtccat gcgcgcccca taagtatcct
     2581 catcccccat ggtcattcca ggaggtagca gagccggcac acttcctgcg ggcgtcttaa
     2641 catctgtcca tcgctgccga gccttgagct gtgggtggtt ccagacgcct tgcatatcat
     2701 tgacgctggc attagcaatc gccgctgcat ccagtcgagc aatcacctgc tccgccgaaa
     2761 gcgacgagaa gacgtcacag attatcttct tcaactcatc acggttctgc gagcgcagcg
     2821 agttattcac aaaccgctca ttcgtagcaa gactgggttg acccaagacg atgtcacaga
     2881 acttagccca ctcacgctca ttctggatcc ccaacatcac cgttccatct cccgtctcaa
     2941 acgggccata aggatagata gccgcatgcg aagcacccgc tggtgtcggg cccggggcat
     3001 tctcataagt ataatacata gggaagccca tccactcaac catgctctcc aacatggaga
     3061 tatcaatgtt acacccccgc ttcgagggat ccctctcccg ctgatacaac gccgccagga
     3121 tattggagta ggcatagcta ccagcggaaa tatcagcgat ggagatgccc accttggcgg
     3181 gctcttttcc cgtccccgtg acggagagca tgccagcctc gctctggatc aacagatcgt
     3241 aggccttctt atcgcggtac ggtccgtcag gaccataccc ggagatgttg cacacaatca
     3301 aggatggatg agccgctttg agatcatcgt aggataaacc cagtcgagca ctggcgccgg
     3361 gagcgaggtt ctggacgagg acatcggcgc ggccgagcag gcgcatgagc acgctgtgat
     3421 cggacggctt tttgaggtcc aaggcgagac tctctttaga ccggttggtc cagacgaagt
     3481 gggaggctag gccgttaacg cgggtgtcat aattgcgagc aaagtctccg acgccaggtc
     3541 gttcgacttt gatgactcgg gctcctaggt cggctagttg gcgggtacag aagggagcgg
     3601 ctatggcttg ttccagactg acgacagtga tgccggcgag ggggccagcc tttttcgtgg
     3661 cgctagtaga agcatggcgc atgccggaga gattatggca tgccgcacgg acaaggggac
     3721 gggtgttagg catggtgctg gttgtgaatt ggggatattt tcgtggggga tgaccccggt
     3781 ttttgaggcc atcgtcgacc ggagaacgtc gccgaccgtg gggtcgcggg ctctctgggg
     3841 tcggttatat gccccgggct ggcctcggtc ccaccattag tttattggga gatgatgtac
     3901 tataagagga tgaaagtcct gccctgatca ttttccagaa gaacaatgaa atctccagaa
     3961 gatatgtatc aggcaaagtg tgttgttccc aaagaactag atatccttcc accctagtaa
     4021 caatctgtct gcaaagattg tgatagcagg tattgaaaca tttttgctat tcattgcatc
     4081 tcaaggcttg atcacggcct atcttctgct aattgttcat tcacagcttt tcccagcttg
     4141 agcatggttg taggaatgat actggaatct ccatctcgca gtcaatccat caatgattcg
     4201 gttactaatt tcgcgcggtc gcataaggtc tactaccaga attcaatcac ggcctgctta
     4261 tttctgatcg tagcgagggc tttagaaagg ttatatagga attgaattgc cgcattacga
     4321 aggagcaatg tgctatgagg cctggtgacc atagcttatt ccagccacgt cgctagcatg
     4381 ccacttggaa aacgatcacc catataactg cgcagctcga actcacaagt tctagacagc
     4441 tacctatatg caaaccgaca aggatactcc ctgccaaata cagccacggg gctattcggc
     4501 tgaacacctg ctggataccg ccggaggtga tcctggacga tgttcatccc aatgcaagca
     4561 ccctggaggc ttttggtcta atatgctgta ctactgcacc tcgtatgcga ccaaataccg
     4621 gagggtcgtc ataacggcca ttgctgatgt cggtcactta caagggacac aagcagcctt
     4681 aacccccaat tgtgaagcta tactacttaa agacgggaag gtcacacttg aacatctgtt
     4741 cctgaagtag ctcggttcaa cgggctagta ttcccatcca gcagatggat aatggctgtt
     4801 ccatcgggga ggacggcatc gtccagggaa ctcgcttgac gatcatcggg ctagcatcag
     4861 gcctccctgg cgtctgattg gtggggttaa tgtgccgttc acgtcaccaa ctttgagacg
     4921 gggaatattc cgatgaatga gacgtgcctt tttcatgtcg gtgtgcagcc gcaagcagat
     4981 gtttcggata catccgaaat tctccgatca gaagcatttg tgctatgacc tgagcagaac
     5041 tgatgcccaa gtcaatactc ggtctgcatt ctttagtgcg gacggaattg taaatctagg
     5101 ccaaactgag gactggccgt gaagggtata ttagcgaatc atattgcccg ctgtcgatat
     5161 gaatcaagtg tcgcatgaac acgtcccaat gtccggcgca gcctgccgta gtccatgaag
     5221 tccgctgccc tgtacattga tccggcagtt ggcatcagag tttaggtatc ctgcggtagt
     5281 tcagcacagt ggagccatgt gggccggcat catcccaata atgggttcga gagtcctccg
     5341 gccagggttc cctggtgtag cttgctcgca gccgctttgt gggatccagc aggtcgcgag
     5401 cggaagaaaa aagactacca gttgaatgct cctggttgct gtcatttggc tccagctcat
     5461 cgtccgacca atgtccacag catatgtatt ttcttttatt gaagattgaa cgggtcagat
     5521 ggcattctgc cactgcgatg acacggtcaa tttcatgccc aaagcgacaa gcgttcgcat
     5581 aattagcgcg accctggtga gccaaatcct tgtcgtgttc gccccatcgg acataacgag
     5641 agccgagggt ccgaggcgaa gcttctcatc gaaacccaga tacttatctt agcgcccgct
     5701 tttattcggt cggacttagc cagtcgtaga ccgaatcgct gtccggaggg accctgtgga
     5761 ggcttttccc tccagaattt gtcattcgct tcatgcatct tcaaatattt gacaagggct
     5821 ctacatatat tggagggaat atctgcttga gagttctggg caagacaaac catgtctgag
     5881 cctaagaacc agccggtaga ggagccaacc atcccgcccg aagaaggggt caagggctgg
     5941 ctgacggtgg ccggaagctt ttgcgcccta ttctcctcct ttgggttcct gaatgcgtat
     6001 gtatagcctg ggtgaatttg cccacctact tcatactgac cttatcacag tatcggagtc
     6061 ttccaaacaa catatcaaca gacgtcgctc aaagattacg acgcgtccga catatcatgg
     6121 attttcgccg tgcagctggc cctcatgtgg gcgccgggac cgctatgggg ccgcatgatt
     6181 gacacttatg gcccgatccc ggtcctctgg ccatgcagca ttctctgtgt gctaggactt
     6241 tgtatgacta gcctggcgca cgagtactat caaatattcc ttgcgcaagg cctctgcttc
     6301 ggcatcggag ccggtggtgt tttcacttcg gccatgattt gcgtcggcca atggttcgtt
     6361 cgccgccgag gccttgcaac tggcattgcg gtatcgggaa gttcacttgg gggtgttatc
     6421 tttcccatat tccttgaccg ggtcatcaat gacatcggct tctatggtgc cgttcggtat
     6481 acagcgctat tcgtcggaat tatgctggca atagcctgcc tactgatccg cagccgtctt
     6541 ccgcgcaaag agtggaacgg taaagcagcg tgggtcgacc tgactctgct gaaggatacc
     6601 gcatttggat tgtacaccgc tggcgcattt ttcatcatgt tcgtcattcg ttcctatcaa
     6661 tggccttacc catccactga cagtgacagg tggggtctct gggccccttt cgactatatt
     6721 tccagcatgg cagagaacgc gggattttcg tcgactcttg ctctctacct gatttctatc
     6781 atcaagtaag gttgcgcaaa acctttcctc gcatctatga tggctgactc ctgtggactt
     6841 cagtgccgcc tccatcttcg gacgtctcat ccctcctcag ctagcagacg tgtttggtca
     6901 cttcaacgtc ctgacactct gctgcttcgg tactggagtg tcaatgctct gtctttggct
     6961 tcctttcaac taccaccctt cacatgcggg cattatcgtc ttctcggcgg tctatggctt
     7021 cgtcagtggc gcggttgtct cccttatgat gccatgtgtt gccaaagtgg gagatctgca
     7081 aaccctgggt cagcgatttg gaacatttca gctaatcatg tcagtaaggt gagtatcaga
     7141 cctttaagca agtcaaattt accggttgct aactttggca gctgcctgac cgggttgccg
     7201 atcatgggag ccatactcga aaagcaaaat tacacggatt actcagggtt gcagcttttt
     7261 ggtgcttgct gtgggatatt agggtcagtt ttgatcggag cagcgacgtt cttgctcagg
     7321 aaaatgcgga atacgagcaa aatatgagtt gagttggtgg ctatcccgcc agccggaaaa
     7381 agaagagaag agaagactct ggtcgttggg acaggacgat gtgagtcgca taaaaatgac
     7441 ttgaacgact tatacatgta ataaatagca taatatagac aggacccttt ggcactcacc
     7501 aaagatagac atggttgatt gtttgaattg tatcgaaaaa tcccgtctgt ggcccaatgt
     7561 ggcgatatgc agcagcgact agcaagtgaa acaggataag cacccatgtt attctatcgt
     7621 ttctctcagt tggttgacag ccatcgtggc agcagaaaga tatgatagat aagccgatga
     7681 tccttatcca atggcttatc agtggtgtcc tcggacgagc tcccaacgcc cccatctctg
     7741 atgctgcaac gccgaagccg agaccccact taccagcact tctccattat atagaaacag
     7801 cgacaatcag agctcctccg agctgcccga acaattttct ctcgtccgac agcatgtggc
     7861 gactacttgg ccggtcatcc aacacttccg agaaaagctc tccgcctcgg agccttccgg
     7921 ggtcatggta tcgctccgat gccatgtatc agctggagcg acgagccatc ttctccaagc
     7981 gttggatgct actcacacat tctagccgac taaccaaacc cggcgacttc ctttccttta
     8041 ccatctccaa tttctccttc tttctaactc gggaccgcga aggtagcatc aatggatttc
     8101 acaacatttg tcgacatcgc gcatacccag ttgtccaagc tcggtctggg gccacctcga
     8161 tcctcagctg caaatatcat ggctggtcct acggactgaa gggcaaccta tcgaaggcac
     8221 ctcgcttcga gactgtatca aacttcgaca aaagtcagca cggactcctc ccaatccatg
     8281 tacatattga taaagcgggc ttcgtctggg tgaatctaga agccggggac ccggaggtca
     8341 agtgggagga tgacttccaa aagatcgatg agcagccgcg gatgcaagac tttgactttg
     8401 acggggaata cacttttgac cattattggg agatggacgt ggaggcgaac tggaagcttc
     8461 tgattgagaa ctacaatgaa tgttatcact gcgcgacctc acatccactg atcaatggag
     8521 tgtcggatct ccctcggtac cgggtcgagc ccaaggcgag gtacatggag catcatatct
     8581 tcaacaagga caatattgat gcgcagttcc gacgatcaat cacgtacttt tacccgacga
     8641 cgtcggtcac agtcacgtaa gtttgtatcc gaaagggaag gtcgatggtc aattgacaca
     8701 agcagggaca aattcttcta tattcaacgc atgatcccag ttagcgcgac aatgagcaag
     8761 atcgaaaacg aagtatatcg acacagagat gccaccgacg aggaattcgc caatatcaac
     8821 gcgttttacc gacaggtctt agacgaagat cgggacctct gtgttggagc gcaagaaaat
     8881 ctgagcgcgg gggtgttcat caacggcgaa ctccacccgg acaaggaaaa ggtatttatg
     8941 acactgtcca gacaggtgta aaattagcaa gcgctaattg tgagcaggga cccatccatt
     9001 ttcaagacca tgtcaagaca atggtcatgg agcaccggcg aaaagaagag gagcaaggcg
     9061 gggaagaaat ctggccagct gttcccaaag tgactgggga gatgaggaca gggaagctgg
     9121 cagaggagga gaggttctgt tctcagctgg aagcggccag ttgcatggcc cgatcagagc
     9181 ttgcttggta atgttttatc tgaatgtgat gttataaagt gataagcgtt cggggcattg
     9241 catattagag acatttgcat tgagcagtca cttcagtcag actgtgttga tttggagaat
     9301 gaaaacatac ccacccaact gtcaagggtg ggggagttcc ctcatctact ccgataacgt
     9361 aacccatccc cttttcccta attggctctc ccactgcagc ttcatactta ctactatttt
     9421 ccactcatgc gttcgtcgcg tcaatcccgt gctttgtcgc cacagctcaa taacgttgaa
     9481 aaagagcagc tggtcattat ttcatgcatt gctcactacc cggtcagctt actcctgtca
     9541 tgaggtcaga gtacgtcaga gcctccctgg tctgtcgatc ggatacccag tgaggacatt
     9601 tccttatatg attgacgaca ggtggacagt ttctgaacta cttagcatta acttaactag
     9661 ccattctcaa ttctaccctg ttttatgggt ggcaatgagc atcccagagc aaactttcca
     9721 acgttcataa agcagagacg catccgcaga tggtcccttt ccggaagctg gggtaggaaa
     9781 acaggattcg gctaaacctt gcagagagga ctgaacgccc tttgactgat atatgttcca
     9841 taagctcagt agtcgccata agggaatgag agataaccat gaatcaaaat gggactcgac
     9901 tatgttattc tgtaagagag gtacctccta caagctttgt ttctgcacct gctaactata
     9961 agcgcgcaag cagtcattgc acttatacca tccctgcagc gtcggcactg acagtgctgt
    10021 actatccatt cttcactgca caagatcgat gcaagatatg catcctaatt acggtacacc
    10081 aattttaccc tgcggcaagg acaacttcag ttgatatgac cgggaatgac agattgccat
    10141 actcgcgacg ctcccgtggg attcctacct catacggtcc gctatctgga cttatccgcc
    10201 agacgcagta gtcggcctca agatacttga tattccgatt gaagaggttt tctttttcgc
    10261 catacagaca tacatcacga gcttgacata ctgtatcttc actaagccgc ttgtgcgacc
    10321 catgtacctt cggtcacatc tggagagacg tggaacaaga tatgtggtag caactgtcat
    10381 tttggcattg atgggtggtg ggacagcgtg cctgctgttg ggacggcgta tgacttacct
    10441 aggcctgatt cttgtgtggg cgtgtcctat cctgctattc cagtggtatg tttggtctac
    10501 gcgtgaatcc attgaggtgc tcatgcgaga acacaggatg atgtcttacc cttttctatc
    10561 cgaacttccc tggaaaccaa caatcacctc aatctgcctc cccacgctac acctctggtt
    10621 tgcagattca cgtgctatgg gtaccgggac ttggaggatc gaggagggca caaaattgaa
    10681 ctttcgtatc ggaggtctag aacttgagtc agtcaggccc accggtgcat tattagacgt
    10741 cggatctaac agtagcagag aagcgctctt ctttctggtg agcaatatga tggtcgtgtt
    10801 aggactggtt gggtgtgact acgcatacgc tcttcaagaa tacgaatccc tatcacagcc
    10861 agcgtcagac gtctacatta cattaagaaa agcactgtcc ttattggcca ggccgcttcc
    10921 aattgacgca tctctcatat ctgcattgtc ccaggctgta tatcgtctgc aagagaagag
    10981 tcagagcatg tttctcggca gcgcattatt ccagggtcag ctgcgcattg atctgatatt
    11041 cctgtattac cccttagtcc aaacgtgctt cattgttctg acatgcatag gtactccttc
    11101 tgccgcgtca tggatgatct cattgacgaa gccgaggatg aacaggaggc cagattttgg
    11161 gttacagagt gcaggcatct cctagattca acccatcgca gtgaaccaca ttccgaccac
    11221 ttttacactg gtaaaaaggg ggaggaacat gaaagactac gtcaatctat cagctacctt
    11281 cctccctcac atctatctaa tgactctttt gatgatcttt taaaagggtt tgagatcgac
    11341 ctcaaattta atccccagag agaagctttc ccgatccagt cggagtattg tctagaccaa
    11401 tacgcaggat ttgtagctgg cactgtcggt gtactggtct tcgaccttac cttattccat
    11461 tgcggtcatt actttatcca ggatgtaccg cgattgaggc gagcggccaa ggatatgggg
    11521 aaagccatgc aatgtatcaa tattgcacgt gatatccatc gcgatgcagc aatcggacga
    11581 gtatacattc ctacaacatg gttgggcgaa gtgggcctaa ctccgggaga tgtattacaa
    11641 tgtcctaact ccccagtcac gtatgatcta caggagagaa tgctgcagaa agcagatgaa
    11701 tattatcagg tcagccgagg ggcgatggag gagctacctc ggggcgtaag agagccattg
    11761 cgggcaaccg tggcgagcta tatggatatt ggactattgc tgagggagcg gaaaggcaca
    11821 agcctggcgc aagcgtcgaa gatgaaggtg cctttggtgc gacggctaaa agttggttgg
    11881 ctggcgatgt tataactgaa ctctgtatgt tgaattgtgt gctacacata tttttcacag
    11941 gtcactgctt cattcaggcc gaatatgtga tttatctcgt caggcatcag aacgctagtg
    12001 ctgacactct tgtcctattg tcagctctcg tctatcggct ggaatgacca catctgttct
    12061 tgggaccttg gcttttgcac cagccggcgc agacaactag gcccgggggt ttcagctaac
    12121 ttcacagatg agatttatct gacagtctga agaaatcgcc tcggcgctac tgtccacccg
    12181 tctgacaaga gcatgtgtgg cgttattcag ctctgcaacg gttcggccac gacttgtatc
    12241 aagagagcgt catcggcaag gacaaccaaa acctcgtctt ttgcttagcc ttgtcttcca
    12301 caacaactct ccggctttac cgataggtct agctagagat tgatacagcc agccactgca
    12361 aaaattccgc agacaagagc tgaaaaagcg accctgagat ttccgggata ctcacaatct
    12421 tttcagtgcc cactagaagg ttgacctgat atggttccac gaatataagg gtgctaagca
    12481 cccaagactg ggagccttct gaagaatact tttcaaacac cgacgcagac atctctatac
    12541 tgcgtaagca gaataaaatc taaaatgcag aggaaactgg aacttgttga ttttacttgc
    12601 ttctacgagt tttgcactta tttactcggc gctgcaggtg ctttgcttga aagcgatgtc
    12661 gtaaagacaa gaccaaacaa tacaagggct tacaaagtga gtgaacattg ctattactca
    12721 tgtttccaga aggctcacaa gtgtatagga agaatggtcc tggaaggacc ttgtcttgac
    12781 tatctggcta tttaccgcgg atgactttac cacatttgtc atacctgaaa cagcattcgg
    12841 gatatgcgcc gctctttccg ggccgcttct gacggacgat aacactccgg acttactctc
    12901 agtcgttagt cggatatcca ttgtcatgct ctggaactgg ctaaacctgt ttgtgtttaa
    12961 cctggcgaat caaaggcacc cggactccgt ggcagaagat aagatcaacc gaccctggag
    13021 accactaccg gcaggtcgga tcagcatcct gcagactcgc cggttgcttc tacttgcaat
    13081 tccaatggtg ctcgcatcca gcgtgtatct aggtgcatgg gaggagactg ctctccttta
    13141 cacccttaac tgggtataca atgacctcag cggtggtgac gacgggttca ttctacggaa
    13201 tgtccttctt gccctcgcgt tcagccaata caacaaggga tcattacgtg ttgcgaccgg
    13261 aactggattc gatatactcc ctagagcatg gcggtggatc tgggtcacca gtgccgtgat
    13321 cggcacgacg atgcatattc aagatatcaa ggacgtggaa ggagaccgtg ccaagaaccg
    13381 ccggacaatg cccattgtga tgggtgacgg gccggcccgg tggtccgttg cagttcctgt
    13441 tgcaatttgg tccgttgttt gtcctgcgtt ttgggagcta gacgttgcca ggtacgttct
    13501 cccggttgcg gtgggaatga ctattgctgg gaggatcttg ttattgcggg aaaaggctgc
    13561 tgataaacgc acgtggaaaa tgtggacggc gtggactgca gttatttggg tgcttccttt
    13621 gttcaagaat gctagtgttt ttgtcaggtt tggtaagaag cttggggtgg tgtgaggcat
    13681 tgctcaagcc aagtgagcga gaatttactt cgcttgcagg ctgttgtggt catgtcactt
    13741 aagtaaatat gacatgacgg gtagctatat cgcacgggag agttgacaga tccagtattt
    13801 tagaaatcag atggtcttct gaaatttctt ccagtttact agatcttaga tcattcaagt
    13861 gccaagaact acaagcagta gcatcattgg tctagtggta gaattcatcg ttgccatcga
    13921 tgaggcccgt gttcgattca cggatgatgc aagcgaattt ctttttgctt ttacccgata
    13981 gcgtccatag tggggttgtt cctgactact attttcttct gcggaaaacc cattttttac
    14041 agcgtcgcgg attgagatgg gcagcaatgg acgatgcaga gaacgacaaa tctaatttgt
    14101 tttctaccat cgatgaaaag ccaatctctt aaacagagga tccaccacga aatatattac
    14161 taatcattct ggtcgaggcc acttcaggaa tactaattgg acacgattgt tgtgttaaat
    14221 cagatatata tatctgctcc gttcaggtag aggtaatttt ctctatgaag ctgctgagac
    14281 gagcaacaaa attactactg cccctactat catcatttca acctttcaat acttggcgta
    14341 ggcatcgtat tactagattg tgtagatgga atttccagtc tccagcaaga cgtaaacatg
    14401 ctcgttccat atactatact accagcttac ggacagtaac aggacacaac caacctaccc
    14461 aaaacattga atataacttc ataatctatt cgtcaaagca tgctcccatc tctatagtag
    14521 cttacagtct actccccata ttaacatgca ccgccttaac ctgcgagtac gcctccagtc
    14581 ccgcctctcc cagctcgcgc ccaataccac tctgcttcac gcctccgaaa gggaccctgg
    14641 gatcgcaatc ctggctacta ttaatccaga ccataccggc ctcgatatcc gccgcgacgc
    14701 gatgcgccct ctccagatcg gtcgtgaaga ccgccgcgcc cagaccatac gtggtatcgt
    14761 tggcgcgacg caccgattcc tcctccgagt cgaatggcag gatgaccacc acgggaccga
    14821 atacttcttc ctggcagatg cgcatgtcat ccgtcacgtc agtgaacact gtcggctcga
    14881 caaagtagcc cttcgcgttc ttttcgtcct tgggagtata ggccttgccg ccggtaacta
    14941 gcgtagcgcc ctcctttttg gctgtttcga tgtacgatag aacgcgctcg tactgtgccc
    15001 gggtaacttg cggcccctga taggtatttt cgtcccactg gtcgccgatc ttggaagtcg
    15061 tctcgatctc cttcttgaac ttctccaaga aggaggcgag aatactacga tgaacgaaga
    15121 tcctcgacgt agcagtgcag atctcgccct tgttggacat gattccgaaa tgcgaccact
    15181 taaccgcctg ttcaagatcc gcatccggga atacgatcaa gggcgacttt ccgcccgtct
    15241 caagggtgat attcttcaat gtgccggcag ccatctttat gatttctcga gcggtggcag
    15301 tagagcctgt gaaggcaatc ttatcgacga gcgggtgctg aaccagcgca gcgccggctt
    15361 cttttccgta gccattgatg acattgacca ctccgggtgg gaatccggct ttcttgatga
    15421 gtgttgcgag gacaaggatg ctgaggggag tttgttcagc ggccttgata acgacggtgt
    15481 ttccgcaggc gagcgcggga ccaagcttcc acgtcgccat cgagagcggg tagttccatg
    15541 ggatgatctg tccgacgacg ccgatgggct ggcggatggt gtatgcgaac ttttgaggag
    15601 tggtgctgat cgtctgtcca aaggtcttat cggcccagcc gctgtagtag cggatggtgg
    15661 tgatggcttc ggtgaggtcc tcggtcaggg cgacgtggta gggttttcct gttggccaag
    15721 tcagtgtctg catatcggtg aggatggtga gtatacgaac cgttatccca agcatcgatg
    15781 gcagcaaata gtgcccggtt ttcttccatc aaatcggcca gacgacccat cagctgtccg
    15841 cgctcggtgg cagggaggag cttccatgaa gggtgcgaca gggccgcttt ggcagcttgg
    15901 acggcggcgt cgacatcctc tgctgttgcg gcgtggacag tggcgatggg cttgtcggta
    15961 ctgtgaagat tagcatggag gcgtagaagg agacaagaat tcgtaggtct tacgccggat
    16021 ctaaagacac gatggtctgg ccactggacg aaggacggaa ctcattgtta atgaacaggc
    16081 cggtcggctg ctggtactgc cgaccattgg gggtggtgat gtcgacaaag agggagtctg
    16141 ccatgttctc ttcttactct tcttcgaaat aacagataac agtagtagca gaagacagtg
    16201 ataatcagcg cgagacagag tgtcctgtct tgatatatgc tacttggcta gaacttcctg
    16261 ttccggatgt gggatgtgcc tccgcgcaga ccacttggca attgacgttt gtcactagtc
    16321 agcaaatccc ccgtccgata aggcgataac aaggataaga tcgtccgatt acccctcact
    16381 tctttgatgt cgagacgcaa tcgatagttt ggcgccggtg gatgcgctaa tgcctcccca
    16441 ctgcatgccg gaactgcctg ccggtgggta atcccgcatc gccagaatgg gcaggtggtt
    16501 ccggcatgtc ttgttacccc tctgagatcc tatccagaca gttagggctt cgttcatact
    16561 gccagaacaa tcatcaaaag tattgtatag acatgaagga gggattgaga gggaaggcag
    16621 tcccgtcgcc gcatgaaata aaaatgccct cgagactcga ctcacgagtc cttcaataat
    16681 tgttctttca gtccttcacg tcattcttcc ttgcctcaac tataccaatc aacaactaca
    16741 accaacatga ctgtcacaca gcaaaccccc gcccttcacg gcatcatggt tgccctgatt
    16801 acccccttca cagacgataa gacccagatc gacgcagcaa gactcaaatc ccacatcgac
    16861 cacctgatcg gcgccggcgt gcatggcctc gtgccgggcg gcagcacagg cgaattcacc
    16921 accatgaccc gcgaagaacg caagcaactg actgagctct gcgtcgagta tgcagctggc
    16981 cgtgtccctg tcgtagcggg cacaggcagt acctccactg aggaggcagt ggatctggca
    17041 cgtcatgccg cgcaggccgg tgcggccgct gtcatggtcg tgccgccatt ctacgacccc
    17101 ttgaacgtgg agcaattgac cgagctcatg tccgaaatcc acgaagccag tcaactgccc
    17161 attgtctact acaatatccc ctctgccagc gggttgaccc tcacaccgca gcagatcgcg
    17221 gatctgagca aggtcggcgt caagtacctc aaagacacat ctggaaatgc tccagcctac
    17281 acggaattgg tgttcgggtt gtcagatcag atcaccgcct tcaatggctg ggataccctt
    17341 acgttctatg gactggcggc tggatcgccg ggagcagttt ggggtgctgc caacatcatc
    17401 ccagagttgg cggtggagct ttggaatgcc gtttcggttg aaggagacct caagaagggt
    17461 cgggaactgt gggccaaggc atggccgatc tgcaagttcc ttgagtcgca caattacgct
    17521 gcagcggtca agacaggcgt ggagctgagg ggacaggcca ctggtgggtt gcggaagcca
    17581 ttcgccctct tgaaggatga tctccagagc gagctggccc agttgatggt gaatgcgaat
    17641 gttaatgttg tcaagcgttc gtcatgaaat agtcgccatt ggatatagaa aaataaattt
    17701 atgaggacat gtcatcgtat ctcttgtagc gccttgtaac agaccccggc ggtcatcatg
    17761 ctagaatggg ccatatttgc ttgcttttga caacatcaag ccaggtcgga aaagtctctc
    17821 ctctgcttcg tgtaaagtgc gcatcttgtt tgtcccatac ctggttcatg acgtcccgga
    17881 cagtatgata ggcagaaaat ccacatcgtg cttcgccttt gtctagcagc agtgtgatcg
    17941 attgccgcct ttcgggcgtc gtcgcctcgc acccagcaat gaaaagaggc cagactgtac
    18001 ctgggccggt gtgatctgct tccactagtg ctacatcaaa ctcgttcaac gatgagatca
    18061 ccttgtccac ctggctctcc aaaatagccg ggtggacctg acggatgcgt ctatagaaga
    18121 agataaccag cgcagaattt aaagcctgta aaaggcatcc atgtgacttg gccaatatgt
    18181 tggtcgaatc gcatatgttg tcctctgttc tcctggacgc gaatgtgcac accatgctct
    18241 cgagacgagc actgcgccga tgcaatgctt cccatgcttc gagacttgca ttattccctt
    18301 gacgcatttc gcgcgcaact cgaaaggttt ccattacatt ggccaggcgt gttgtttgag
    18361 ataccaagct gagccacgtc tccgataccc cgtaaatctg gctatatagt gtggcaggat
    18421 acttgcgcga atcctgcaaa tgaatatcat ataggccaac gtcgtcctcc ttcggctcat
    18481 caatgtccag gtcgctatcg gacgggcgcc gatcgaggcg caaaaagtcg tccaagcgtg
    18541 atgttcggta cccagctgct tgagtatttt cgactttctg ataccgaaac cgatatttga
    18601 gagcctccat aaaggcatcc gagggcgtgt agttgtgcaa agcgtaggtg ctctcaccta
    18661 caattcgtag ccacgtatat gtgtggtgta ggaggcgtgc tttttgagaa atccgttgtt
    18721 taggcaaccc tcggaggcgg agcagccgct cagcatcgat catatagcat cttgcatcct
    18781 gctgctgact acttaggatc tgtttccctc agtaagctac ctcgaacaaa gttagacagg
    18841 aatcatacag caaattcagt caaggcgcaa attgccatga gctggtcctt gtatttggcc
    18901 ttctttggct cttgtgtttc atgcttcaga gacatctgca tgtgatcttt tgccagatgg
    18961 taagcatatt ccgctaccgg cttccatcgt tctgttgagt ccgaggtcct catggaaggg
    19021 tttaccgtta aatggagggc tgaacaggcc aagaggcagt acagattggc taatcgagca
    19081 tgagtgatgt tttgcgaccc cagaaaagtg atatcgctat atgttacaac agcagatggc
    19141 acattgagta tcttccaagg tgacttctgg tctagaggaa cggccatcat acgcgaaatg
    19201 acatgatcct ggaaatgtcg tagtaggtaa tgagcatctg ctagtacatc aggtggattg
    19261 ctatcaaccg gcggcaccat cttggaggca ttgtcttgcc cagggacaca atggtagaga
    19321 gctgctgtat catccatcag actaggagct tcgccaagga gattatgttc cagcataggg
    19381 gcttgtgtcc ccaaatccag gggcaaccaa tcgcccaggt cgaatgtgcc agatagtgta
    19441 gcactctgca actgaggatc caagctaaga atatctgacc actgcagcag gtcattcatg
    19501 taggcgatcg actcttgcga cagagctgga ctgactccgg aagcgccttc agccagggta
    19561 tcccccgacg gtagaatcac atcatttgcg accgtagtct cgtcagtggg atgagcccga
    19621 cttgcagatt tgggttcggt aaggctaaag tccagcacag caaatggtcc aactacaata
    19681 tcgccctgtg agggcctctc cgtatcccgg gatcttgttt cgatctcagc caatgaggca
    19741 tcaatagagc ccgacaccaa gtctgcactc aatgcatcgc tcatggagac tctcgacttt
    19801 tctaatgtct atacattagc tttaccattt tgaagccggt gatcagatca tcgatgtatg
    19861 agagagggtg atcaacctgt gtagagatgg cgtcgaggcc cctgcttctc cggatcattt
    19921 gccttcttag ctgttgtccc cgaagaaggc tgggacttcc gatcggacat ccatcggatc
    19981 tcatcaacga acccctcaca taccacacct gttgcccgac acatctggca ggtaggcctc
    20041 ttttggtcgc atttggcatg acgccttcga cacgttctgc aggctcccag ggcatgactg
    20101 cgacgagtcc ggcggcctga ttgcttggag gaagtcatgt cactcagagc agggcattat
    20161 caacgaaaac ggaaagaaag ggtaatcgaa cagaatctgg ggtatgagtc gggtggccct
    20221 ggagctggaa ggtgaagcaa ttattagcag gtcccccaga aaggagggtg tggcccgacc
    20281 gggcaggcag gcggttccgg cggggcggaa tctccttcct gttcggacca gaacagcgtc
    20341 ggaaggacct gctctcccgg gtttagcctt tcagtatctt ggaagcttga tgacaccgag
    20401 ttgtatgggc gataactaga tatgttgact tcggtgggaa tggacaattg tattgtaagt
    20461 gaatttattc aggtattcta ataactccaa gatagatcta tttcagtccc agtctctggg
    20521 cctcggcaag aacagtgtgt gggatttcct cttccaacgt ccttccttcg gggacccatt
    20581 tcaggtactt ggccgctcgc tgagccacct gctgggcatt ggttccccac aacactccgc
    20641 catgaggcgt gagtgaatcg gcctcttcat ggctgatctc agttaccgac tcggactcag
    20701 caaggccgag ctttttcact tcttgcgcca ctcgtgctga gatggaaccg aatgactgta
    20761 ctctcgttag aatgtacctt gttctgtgct taggtcggag catgtaagaa cttacgatag
    20821 ccctggaacc ggggaaatac aacccgttct cattccacaa tttcccttcc tcactttgca
    20881 aagccttctc ggccagcttc acaaagatgt tgctgacatc cgagatgtgc acattactcc
    20941 atgtggcttc tcctctgccc acctgaaccc cgccccgtcg ctgcatggtc actcttgcca
    21001 gctccgggat ttgtatgctc cgctggttaa tcggtcccct accgcgaccg taaatgatcg
    21061 ggggaaatat taacgcggtt ttaggacgag aggaagtatg gggaaggctg aggactagat
    21121 tgtcaaccac acgcttggca gagtactgtc gaatgagctc ccgcagctca tcagcaccat
    21181 cgacatcgct gtaaatcttg ttggagggcc ctccaaaggc gctggctaca atgtcaggaa
    21241 tggaaaggac gcttgcgcct gatatctgaa gccagtgacc tgcttgattc atgagaagtg
    21301 tgaggggacg gaacgaatgg gaggtaatta cccggctttg gtctttccgg tgcagtcaat
    21361 ccacgcgcga tggcttcggc gctctttacg tgatttgagc ttgcggtgtc tgagaaagga
    21421 ggccaatatt agcagaaggc agaaagaatt gaagcaagaa cactcacgga tgacgatatc
    21481 tgcttctcgt gcctgttgtt ccaaagtgga agaggcgtcc aaatctccca ggactacttg
    21541 tacatcaggg tacgcttgag agagtttctg agccttcgcc tcgtctctca gcaagactgt
    21601 atactggcaa gttggaaggg ctgatttcag cgcatggagg acatcccctc caatataacc
    21661 tgaggctcct gtactatgat ttctgttagt agcaaggaag aggacgaatc cctggatgta
    21721 cctacagaaa gattttcgcc at
//
