Identified secondary metabolite regions

OGUI01000018.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 2.1 bacteriocin 10,965 21,655
OGUI01000015.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 3.1 T1PKS 402,086 430,886 Aflavarin t1pks 60%
Region 3.2 T1PKS 505,125 553,617
OGUI01000001.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 5.1 NRPS,T1PKS 521,016 568,049 HC-toxin NRPS 100%
Region 5.2 terpene 577,621 598,838
Region 5.3 NRPS-like,T1PKS 1,209,407 1,256,552
Region 5.4 NRPS 1,867,110 1,923,741 Aflatrem terpene 17%
Region 5.5 T1PKS 2,044,662 2,090,547
Region 5.6 NRPS,T1PKS 2,132,346 2,240,227 Azanigerone t1pks 93%
OGUI01000017.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 6.1 terpene 202,676 224,423
Region 6.2 T3PKS 315,554 356,784
Region 6.3 NRPS 524,389 578,414
Region 6.4 NRPS 1,078,303 1,128,618
Region 6.5 terpene 1,842,613 1,860,861
Region 6.6 terpene 2,017,009 2,039,027
Region 6.7 NRPS-like 2,127,997 2,167,871
Region 6.8 NRPS,T1PKS 2,381,574 2,433,416 Phyllostictine A / phyllostictine B nrps-t1pks 20%
Region 6.9 NRPS 2,758,948 2,815,510 Nidulanin A polyketide 75%
Region 6.10 T1PKS 4,396,073 4,437,466 Fusarielin H t1pks 50%
Region 6.11 T1PKS,NRPS 4,855,148 4,907,107 Pyranonigrin E polyketide 100%
OGUI01000002.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 7.1 terpene 150,544 166,277 Clavaric acid terpene 100%
Region 7.2 terpene 252,308 270,631
Region 7.3 T1PKS 320,389 363,897 Naphthopyrone t1pks 100%
Region 7.4 T1PKS 415,159 463,336
Region 7.5 NRPS-like 488,060 531,166
Region 7.6 terpene 1,078,355 1,099,311
OGUI01000004.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 8.1 NRPS 97,282 154,490
Region 8.2 T1PKS 686,702 730,602
Region 8.3 T1PKS 912,525 955,885
Region 8.4 T1PKS 1,313,540 1,361,844
OGUI01000013.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 9.1 terpene 261,558 283,173 HC-toxin NRPS 100%
Region 9.2 T1PKS 319,649 366,761
Region 9.3 T1PKS 388,429 434,301 Duclauxin t1pks 50%
Region 9.4 NRPS-like 445,516 484,743
Region 9.5 NRPS 519,822 558,685
Region 9.6 T1PKS 613,913 657,548
Region 9.7 NRPS-like 1,179,368 1,221,367
Region 9.8 T1PKS,NRPS-like 1,996,358 2,050,699 HC-toxin NRPS 100%
Region 9.9 NRPS-like 2,244,605 2,282,471
Region 9.10 siderophore 2,293,139 2,305,282
Region 9.11 NRPS 2,466,203 2,513,280
OGUI01000003.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 10.1 NRPS-like 50,290 91,780
Region 10.2 betalactone 479,629 508,739
Region 10.3 NRPS-like 834,346 878,581
Region 10.4 T1PKS,NRPS 1,965,359 2,044,847 Fumonisin t1pks 47%
Region 10.5 T1PKS 3,133,468 3,179,948
Region 10.6 terpene 3,326,754 3,348,583
Region 10.7 indole 4,321,013 4,342,463
Region 10.8 T1PKS,NRPS-like 4,446,876 4,499,853 Notoamide NRPS 11%
Region 10.9 NRPS,T1PKS 4,543,231 4,613,882 Aureobasidin A1 NRPS 100%
OGUI01000011.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 11.1 NRPS-like 116,026 159,121
OGUI01000010.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 12.1 T1PKS 13,744 59,107 Yanuthone D t1pks 100%
Region 12.2 terpene 408,816 429,775
Region 12.3 NRPS 1,631,408 1,692,712
OGUI01000006.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 13.1 terpene 492,568 514,173
Region 13.2 T1PKS 534,463 573,673 Azaphilone t1pks 8%
Region 13.3 T1PKS,NRPS 659,225 762,440
Region 13.4 NRPS 939,193 995,685
OGUI01000016.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 14.1 NRPS 41,840 91,296
Region 14.2 NRPS,T1PKS 106,598 157,663 Pyranonigrin E polyketide 100%
Region 14.3 terpene 663,434 683,094 Aflatrem terpene 11%
Region 14.4 T1PKS 942,909 989,501
Region 14.5 T1PKS 1,011,287 1,051,842
Region 14.6 T1PKS 1,115,792 1,160,889 Communesin polyketide 12%
Region 14.7 NRPS-like,T1PKS 1,404,466 1,474,010
Region 14.8 terpene 1,593,494 1,614,255
Region 14.9 NRPS,T1PKS 1,618,876 1,670,895 Wortmanamide A t1pks 100%
Region 14.10 T1PKS 1,792,562 1,837,943 TAN-1612 t1pks 100%
OGUI01000005.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 15.1 NRPS-like 6,341 46,336
Region 15.2 terpene 62,914 83,693
Region 15.3 NRPS-like 207,540 245,588
Region 15.4 NRPS 833,288 885,350
Region 15.5 T1PKS 886,405 933,218
OGUI01000007.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 16.1 NRPS,T1PKS 2,239 42,045 Isoflavipucine nrps-t1pks 12%
Region 16.2 T1PKS 191,511 231,900
Region 16.3 indole 544,845 566,044
Region 16.4 terpene 3,435,564 3,456,894
Region 16.5 NRPS-like 3,650,920 3,672,640
Region 16.6 T1PKS 3,827,210 3,866,100 Pyripyropene A terpene-t1pks 25%
Region 16.7 T1PKS,NRPS 4,149,058 4,201,157 Wortmanamide A t1pks 100%
Region 16.8 NRPS 4,981,815 5,027,524
OGUI01000008.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 17.1 NRPS-like 97,739 139,456
Region 17.2 T1PKS 141,129 189,697
Region 17.3 NRPS-like 227,395 270,714
OGUI01000014.1 (Aspergillus niger)
Region Type From To Most similar known cluster Similarity
Region 18.1 NRPS 2,398 40,016
Region 18.2 T1PKS 55,072 94,019
Region 18.3 NRPS,terpene 162,864 207,807
Region 18.4 terpene 213,401 236,481 Aflatrem terpene 11%
Region 18.5 T1PKS 386,452 432,916
Region 18.6 NRPS 721,124 767,332
No secondary metabolite regions were found in these records:
OGUI01000019.1 (Aspergillus niger)
OGUI01000012.1 (Aspergillus niger)
OGUI01000009.1 (Aspergillus niger)
Compact view
OGUI01000018.1 - Region 1 - bacteriocin
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 10,965 - 21,655 nt. (total: 10,691 nt) Show pHMM detection rules used
bacteriocin: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03603 or TIGR03604 or TIGR03651 or TIGR03678 or TIGR03693 or TIGR03798 or TIGR03601 or TIGR03602 or TIGR03795 or TIGR03793 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000015.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 402,086 - 430,886 nt. (total: 28,801 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 402085 - 430886:
Polymer prediction:
(mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_86310: mal
PKS_AT (915..1214): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 71.5
inactive: 51.9
Methoxymalonyl-CoA: 45.1
Methylmalonyl-CoA: 40.2
2-Methylbutyryl-CoA: 19.3
Propionyl-CoA: 18.2
Isobutyryl-CoA: 14.2
Ethylmalonyl-CoA: 13.9
fatty_acid: 12.7
CHC-CoA: 12.4
trans-1,2-CPDA: 11.9
3-Methylbutyryl-CoA: 10.6
Benzoyl-CoA: 9.8
Acetyl-CoA: 0.0


OGUI01000015.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 505,125 - 553,617 nt. (total: 48,493 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 505124 - 553617:
Polymer prediction:
(redmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_86730: redmal
PKS_AT (577..922): redmal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 62.5%
inactive: 54.2%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 92.1
Methoxymalonyl-CoA: 78.8
Methylmalonyl-CoA: 78.2
Isobutyryl-CoA: 56.8
Ethylmalonyl-CoA: 49.9
inactive: 41.9
Propionyl-CoA: 39.1
Benzoyl-CoA: 29.8
2-Methylbutyryl-CoA: 20.4
Acetyl-CoA: 16.4
fatty_acid: 16.3
trans-1,2-CPDA: 15.9
3-Methylbutyryl-CoA: 10.3
CHC-CoA: 7.7


OGUI01000001.1 - Region 1 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 521,016 - 568,049 nt. (total: 47,034 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 521015 - 568049:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(ccmmal - hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_1730: ccmmal - hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

PKS_AT (545..852): ccmmal
ATSignature: Malonyl-CoA, Methylmalonyl-CoA
Top 3 matches:
Malonyl-CoA: 62.5%
Methylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 63.4
Methoxymalonyl-CoA: 52.0
Benzoyl-CoA: 31.0
Isobutyryl-CoA: 28.7
trans-1,2-CPDA: 26.3
inactive: 18.5
Propionyl-CoA: 10.7
2-Methylbutyryl-CoA: 1.0
Malonyl-CoA: 0.6
fatty_acid: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
Ethylmalonyl-CoA: -0.3

AMP-binding (2993..3402): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
gltllalfgk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000001.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 577,621 - 598,838 nt. (total: 21,218 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000001.1 - Region 3 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,209,407 - 1,256,552 nt. (total: 47,146 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 1209406 - 1256552:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_4030: X - mal
Search NORINE for peptide: strict or relaxed

AMP-binding (24..423): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmfvvglask
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

PKS_AT (1161..1455): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
inactive: 66.7%
Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 162.6
inactive: 74.8
Methoxymalonyl-CoA: 73.9
Methylmalonyl-CoA: 66.3
Isobutyryl-CoA: 42.7
Propionyl-CoA: 37.3
Acetyl-CoA: 31.3
Ethylmalonyl-CoA: 30.8
Benzoyl-CoA: 29.8
trans-1,2-CPDA: 28.8
CHC-CoA: 27.6
fatty_acid: 18.8
2-Methylbutyryl-CoA: 17.4
3-Methylbutyryl-CoA: 0.0


OGUI01000001.1 - Region 4 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,867,110 - 1,923,741 nt. (total: 56,632 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 1867109 - 1923741:
Polymer prediction:
(hydrophobic-aromatic) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_6220: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (22..333): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
--pphslgqk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ATCC64974_6280: hydrophobic-aromatic
Search NORINE for peptide: strict or relaxed

AMP-binding (532..913): hydrophobic-aromatic
NRPSPredictor2: hydrophobic-aromatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aromatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dghiyvmcgk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000001.1 - Region 5 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 2,044,662 - 2,090,547 nt. (total: 45,886 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 2044661 - 2090547:
Polymer prediction:
(redmmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_6900: redmmal
PKS_AT (487..792): redmmal
ATSignature: Methylmalonyl-CoA, Malonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 70.8%
Malonyl-CoA: 70.8%
Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 78.6
Methoxymalonyl-CoA: 68.2
Malonyl-CoA: 55.8
Isobutyryl-CoA: 48.7
Ethylmalonyl-CoA: 47.2
Propionyl-CoA: 40.3
trans-1,2-CPDA: 29.2
Benzoyl-CoA: 28.4
fatty_acid: 20.5
2-Methylbutyryl-CoA: 18.6
Acetyl-CoA: 13.9
CHC-CoA: 13.3
3-Methylbutyryl-CoA: 9.0
inactive: 0.0


OGUI01000001.1 - Region 6 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 2,132,346 - 2,240,227 nt. (total: 107,882 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 2132345 - 2240227:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - hydrophobic-aliphatic) + (pk) + (hydrophobic-aliphatic) + (pk) + (redmal)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 7, location 2132345 - 2180886:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - hydrophobic-aliphatic) + (pk)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 8, location 2172417 - 2240227:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (hydrophobic-aliphatic) + (pk) + (redmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_7190: X - hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (240..636): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvlfvggvak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1748..2143): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvlfvggvak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ATCC64974_7230: pk
PKS_AT (1687..1946): pk
ATSignature: (unknown)
No matches above 50%

minowa: trans-1,2-CPDA
Prediction, score:
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0


ATCC64974_7280: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (21..441): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
aasargvcik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ATCC64974_7320: pk
PKS_AT (900..1149): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Ethylmalonyl-CoA: 54.2%
inactive: 54.2%

minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 49.2
Methylmalonyl-CoA: 45.4
inactive: 37.8
Malonyl-CoA: 34.2
Propionyl-CoA: 22.4
CHC-CoA: 21.7
trans-1,2-CPDA: 19.9
Ethylmalonyl-CoA: 18.0
Isobutyryl-CoA: 16.9
2-Methylbutyryl-CoA: 16.5
Benzoyl-CoA: 14.3
3-Methylbutyryl-CoA: 13.6
Acetyl-CoA: 11.0
fatty_acid: 0.0


ATCC64974_7380: redmal
PKS_AT (598..920): redmal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 66.7%
Methylmalonyl-CoA: 62.5%
Isobutyryl-CoA: 54.2%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 90.9
Methylmalonyl-CoA: 66.1
Methoxymalonyl-CoA: 65.2
Isobutyryl-CoA: 29.8
Benzoyl-CoA: 22.3
inactive: 22.1
trans-1,2-CPDA: 17.0
fatty_acid: 16.3
CHC-CoA: 16.2
Propionyl-CoA: 15.7
2-Methylbutyryl-CoA: 14.7
Ethylmalonyl-CoA: 5.9
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


OGUI01000017.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 202,676 - 224,423 nt. (total: 21,748 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000017.1 - Region 2 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 315,554 - 356,784 nt. (total: 41,231 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000017.1 - Region 3 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 524,389 - 578,414 nt. (total: 54,026 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 524388 - 578414:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - pro - X) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_97650: X - pro - X
Search NORINE for peptide: strict or relaxed

AMP-binding (238..683): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dpamwitiak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1377..1786): pro
NRPSPredictor2: pro
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
pro
Stachelhaus prediction details:
Stachelhaus sequence:
dvqhtitvvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2502..2907): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dplstgaigk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ATCC64974_97660: X
Search NORINE for peptide: strict or relaxed

AMP-binding (48..471): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
gllhiasptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000017.1 - Region 4 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,078,303 - 1,128,618 nt. (total: 50,316 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 1078302 - 1128618:
Polymer prediction:
(hydrophobic-aromatic)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_99310: hydrophobic-aromatic
Search NORINE for peptide: strict or relaxed

AMP-binding (105..547): hydrophobic-aromatic
NRPSPredictor2: hydrophobic-aromatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aromatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
imvgttigck
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000017.1 - Region 5 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,842,613 - 1,860,861 nt. (total: 18,249 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000017.1 - Region 6 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 2,017,009 - 2,039,027 nt. (total: 22,019 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000017.1 - Region 7 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 2,127,997 - 2,167,871 nt. (total: 39,875 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 7, location 2127996 - 2167871:
Polymer prediction:
(hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_102540: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (23..349): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
aayldcc--k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000017.1 - Region 8 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 2,381,574 - 2,433,416 nt. (total: 51,843 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 8, location 2381573 - 2433416:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk - gln)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_103380: pk - gln
Search NORINE for peptide: strict or relaxed

PKS_AT (550..868): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 76.3
Methoxymalonyl-CoA: 61.9
Ethylmalonyl-CoA: 55.9
Malonyl-CoA: 37.3
Isobutyryl-CoA: 34.7
Benzoyl-CoA: 28.7
Propionyl-CoA: 23.5
fatty_acid: 22.5
trans-1,2-CPDA: 20.4
Acetyl-CoA: 14.5
CHC-CoA: 12.1
3-Methylbutyryl-CoA: 10.1
inactive: 0.0
2-Methylbutyryl-CoA: -1.3

AMP-binding (3012..3421): gln
NRPSPredictor2: gln
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
glu, gln
Single AA prediction:
gln
Stachelhaus prediction details:
Stachelhaus sequence:
nhdkfgsisk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000017.1 - Region 9 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 2,758,948 - 2,815,510 nt. (total: 56,563 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 9, location 2758947 - 2815510:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - X - hydrophilic - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_104520: X - X - hydrophilic - X
Search NORINE for peptide: strict or relaxed

AMP-binding (254..652): X
NRPSPredictor2: phe, trp, phg, tyr, bht
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aromatic
Large clusters prediction:
phe, trp, phg, tyr, bht
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
daviiaavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1797..2197): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmqsvafssk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2839..3243): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvlstgavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3930..4331): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
damfvggifk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000017.1 - Region 10 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 4,396,073 - 4,437,466 nt. (total: 41,394 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 10, location 4396072 - 4437466:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_109730: pk
PKS_AT (552..871): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 62.5%
Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 81.6
Methoxymalonyl-CoA: 68.0
Ethylmalonyl-CoA: 60.6
Propionyl-CoA: 39.4
Benzoyl-CoA: 30.2
fatty_acid: 24.9
trans-1,2-CPDA: 23.1
Isobutyryl-CoA: 21.4
2-Methylbutyryl-CoA: 19.6
3-Methylbutyryl-CoA: 12.9
Malonyl-CoA: 7.4
CHC-CoA: 6.0
inactive: 0.0
Acetyl-CoA: 0.0


OGUI01000017.1 - Region 11 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 4,855,148 - 4,907,107 nt. (total: 51,960 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 11, location 4855147 - 4907107:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(redmal - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_111360: redmal - X
Search NORINE for peptide: strict or relaxed

PKS_AT (573..889): redmal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 62.5%
inactive: 58.3%

minowa: Isobutyryl-CoA
Prediction, score:
Isobutyryl-CoA: 77.4
Methylmalonyl-CoA: 76.9
Methoxymalonyl-CoA: 69.4
Malonyl-CoA: 62.0
Ethylmalonyl-CoA: 41.3
Propionyl-CoA: 33.7
inactive: 30.4
3-Methylbutyryl-CoA: 29.7
2-Methylbutyryl-CoA: 27.8
Benzoyl-CoA: 24.2
trans-1,2-CPDA: 21.6
Acetyl-CoA: 13.8
CHC-CoA: 12.1
fatty_acid: 11.4

AMP-binding (2865..3274): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dlgylccvqk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000002.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 150,544 - 166,277 nt. (total: 15,734 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000002.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 252,308 - 270,631 nt. (total: 18,324 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000002.1 - Region 3 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 320,389 - 363,897 nt. (total: 43,509 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 320388 - 363897:
Polymer prediction:
(mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_8540: mal
PKS_AT (912..1211): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 100.0%
Methylmalonyl-CoA: 62.5%
Isobutyryl-CoA: 58.3%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 110.5
inactive: 48.6
Methoxymalonyl-CoA: 48.3
Methylmalonyl-CoA: 44.4
Propionyl-CoA: 19.9
Benzoyl-CoA: 17.2
2-Methylbutyryl-CoA: 15.8
Ethylmalonyl-CoA: 13.2
Isobutyryl-CoA: 12.5
CHC-CoA: 11.2
fatty_acid: 10.4
trans-1,2-CPDA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


OGUI01000002.1 - Region 4 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 415,159 - 463,336 nt. (total: 48,178 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 415158 - 463336:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_8850: pk
PKS_AT (537..805): pk
ATSignature: Malonyl-CoA, Methylmalonyl-CoA
Top 3 matches:
Malonyl-CoA: 58.3%
Methylmalonyl-CoA: 58.3%

minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 38.7
Methylmalonyl-CoA: 33.2
Malonyl-CoA: 20.6
fatty_acid: 15.1
2-Methylbutyryl-CoA: 11.7
CHC-CoA: 11.2
Isobutyryl-CoA: 10.7
Propionyl-CoA: 9.8
Benzoyl-CoA: 9.0
trans-1,2-CPDA: 7.9
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
Ethylmalonyl-CoA: -2.2


OGUI01000002.1 - Region 5 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 488,060 - 531,166 nt. (total: 43,107 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 488059 - 531166:
Polymer prediction:
(hydrophilic)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_9050: hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (9..431): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
vamflgsagk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000002.1 - Region 6 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,078,355 - 1,099,311 nt. (total: 20,957 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000004.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 97,282 - 154,490 nt. (total: 57,209 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 97281 - 154490:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - X - X - hydrophobic-aliphatic - leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_26970: X - X - X - hydrophobic-aliphatic - leu
Search NORINE for peptide: strict or relaxed

AMP-binding (234..634): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
tmyvaggalk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1343..1742): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dfiivgapik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2433..2830): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dlyiiglqck
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3523..3921): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
davviaamvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (4640..5035): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dailvgaqik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000004.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 686,702 - 730,602 nt. (total: 43,901 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 686701 - 730602:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_28870: pk
PKS_AT (587..904): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 58.3%
Isobutyryl-CoA: 58.3%

minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 71.8
Methylmalonyl-CoA: 67.7
Malonyl-CoA: 38.7
Propionyl-CoA: 37.9
Isobutyryl-CoA: 37.9
Ethylmalonyl-CoA: 37.6
inactive: 25.6
2-Methylbutyryl-CoA: 20.8
fatty_acid: 10.1
trans-1,2-CPDA: 8.8
Benzoyl-CoA: 5.3
Acetyl-CoA: 1.7
CHC-CoA: 0.0
3-Methylbutyryl-CoA: -2.9


OGUI01000004.1 - Region 3 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 912,525 - 955,885 nt. (total: 43,361 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 912524 - 955885:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_29660: pk
PKS_AT (631..951): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 62.5%
Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 66.3
Malonyl-CoA: 63.1
Methoxymalonyl-CoA: 54.1
Ethylmalonyl-CoA: 38.7
Isobutyryl-CoA: 28.5
2-Methylbutyryl-CoA: 18.7
Propionyl-CoA: 18.2
trans-1,2-CPDA: 17.4
inactive: 17.3
Benzoyl-CoA: 15.2
CHC-CoA: 15.1
fatty_acid: 7.5
Acetyl-CoA: 1.4
3-Methylbutyryl-CoA: 0.0


OGUI01000004.1 - Region 4 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,313,540 - 1,361,844 nt. (total: 48,305 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 1313539 - 1361844:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_30970: pk
PKS_AT (612..937): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
Methylmalonyl-CoA: 66.7%
2-Methylbutyryl-CoA: 58.3%

minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 75.8
Methylmalonyl-CoA: 68.4
Malonyl-CoA: 59.6
Isobutyryl-CoA: 43.3
Propionyl-CoA: 36.5
Ethylmalonyl-CoA: 31.9
inactive: 21.9
fatty_acid: 21.5
Benzoyl-CoA: 19.7
3-Methylbutyryl-CoA: 18.4
CHC-CoA: 17.5
trans-1,2-CPDA: 15.4
2-Methylbutyryl-CoA: 14.4
Acetyl-CoA: 0.0


OGUI01000013.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 261,558 - 283,173 nt. (total: 21,616 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000013.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 319,649 - 366,761 nt. (total: 47,113 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 319648 - 366761:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_74860: pk
PKS_AT (569..876): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Methylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 66.3
Malonyl-CoA: 58.4
Methoxymalonyl-CoA: 54.1
Isobutyryl-CoA: 40.4
Ethylmalonyl-CoA: 36.8
Benzoyl-CoA: 29.0
fatty_acid: 28.5
inactive: 16.2
CHC-CoA: 12.6
trans-1,2-CPDA: 11.5
2-Methylbutyryl-CoA: 11.0
Propionyl-CoA: 10.4
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


OGUI01000013.1 - Region 3 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 388,429 - 434,301 nt. (total: 45,873 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 388428 - 434301:
Polymer prediction:
(mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_75090: mal
PKS_AT (923..1222): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 85.9
inactive: 42.8
Methoxymalonyl-CoA: 36.2
Methylmalonyl-CoA: 32.7
Isobutyryl-CoA: 24.7
CHC-CoA: 22.0
2-Methylbutyryl-CoA: 21.7
Propionyl-CoA: 18.2
Ethylmalonyl-CoA: 18.0
Acetyl-CoA: 16.2
Benzoyl-CoA: 15.0
fatty_acid: 13.7
3-Methylbutyryl-CoA: 11.1
trans-1,2-CPDA: 0.0


OGUI01000013.1 - Region 4 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 445,516 - 484,743 nt. (total: 39,228 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 445515 - 484743:
Polymer prediction:
(pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_75290: pro
Search NORINE for peptide: strict or relaxed

AMP-binding (4..406): pro
NRPSPredictor2: pro
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
pro, pip
Small clusters prediction:
pro
Single AA prediction:
pro
Stachelhaus prediction details:
Stachelhaus sequence:
dmfflativk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000013.1 - Region 5 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 519,822 - 558,685 nt. (total: 38,864 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 519821 - 558685:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(ala - hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_75560: ala - hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (48..447): ala
NRPSPredictor2: ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
gly, ala
Single AA prediction:
ala
Stachelhaus prediction details:
Stachelhaus sequence:
dasgllipyk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1119..1530): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dahnilapvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000013.1 - Region 6 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 613,913 - 657,548 nt. (total: 43,636 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 613912 - 657548:
Polymer prediction:
(redmmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_75780: redmmal
PKS_AT (304..593): redmmal
ATSignature: Malonyl-CoA, Methylmalonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 75.0%
Ethylmalonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 66.8
Methoxymalonyl-CoA: 60.6
Malonyl-CoA: 46.2
Isobutyryl-CoA: 37.0
Propionyl-CoA: 23.6
Ethylmalonyl-CoA: 21.7
2-Methylbutyryl-CoA: 12.3
3-Methylbutyryl-CoA: 10.2
trans-1,2-CPDA: 6.2
inactive: 0.0
fatty_acid: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: -1.3


OGUI01000013.1 - Region 7 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,179,368 - 1,221,367 nt. (total: 42,000 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 7, location 1179367 - 1221367:
Polymer prediction:
(leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_77220: leu
Search NORINE for peptide: strict or relaxed

AMP-binding (6..406): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dlfflgttlk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000013.1 - Region 8 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,996,358 - 2,050,699 nt. (total: 54,342 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 8, location 1996357 - 2050699:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk) + (X)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 9, location 1996357 - 2043801:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk) + (X)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 10, location 2014216 - 2050699:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_79950: X
Search NORINE for peptide: strict or relaxed

AMP-binding (17..443): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
fswygavvfk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ATCC64974_79960: pk
PKS_AT (547..861): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Methylmalonyl-CoA: 62.5%
Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 64.3
Methoxymalonyl-CoA: 58.3
Ethylmalonyl-CoA: 47.4
Isobutyryl-CoA: 37.7
Malonyl-CoA: 35.0
trans-1,2-CPDA: 25.0
Benzoyl-CoA: 24.6
fatty_acid: 16.8
CHC-CoA: 14.2
2-Methylbutyryl-CoA: 13.1
Propionyl-CoA: 8.7
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


ATCC64974_79990: X
Search NORINE for peptide: strict or relaxed

AMP-binding (7..412): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmcivggifk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000013.1 - Region 9 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 2,244,605 - 2,282,471 nt. (total: 37,867 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 11, location 2244604 - 2282471:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_80640: X
Search NORINE for peptide: strict or relaxed

AMP-binding (268..736): X
NRPSPredictor2: asp, asn, glu, gln, aad
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dprhfvmrak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000013.1 - Region 10 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 2,293,139 - 2,305,282 nt. (total: 12,144 nt) Show pHMM detection rules used
siderophore: IucA_IucC

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000013.1 - Region 11 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 2,466,203 - 2,513,280 nt. (total: 47,078 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 13, location 2466202 - 2513280:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_81350: X - X
Search NORINE for peptide: strict or relaxed

AMP-binding (290..669): X
NRPSPredictor2: asp, asn, glu, gln, aad
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
sardvgsqlk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1313..1697): X
NRPSPredictor2: phe, trp
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
phe, trp
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dgfcagaick
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000003.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 50,290 - 91,780 nt. (total: 41,491 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 50289 - 91780:
Polymer prediction:
(hydrophilic)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_11540: hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (101..359): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hasymgh--k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000003.1 - Region 2 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 479,629 - 508,739 nt. (total: 29,111 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000003.1 - Region 3 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 834,346 - 878,581 nt. (total: 44,236 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 834345 - 878581:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(val) + (X)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 4, location 834345 - 873017:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(val) + (X)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 5, location 843634 - 878581:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(val) + (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_13990: X
Search NORINE for peptide: strict or relaxed

AMP-binding (59..458): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
---fnggagk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ATCC64974_14020: val
Search NORINE for peptide: strict or relaxed

AMP-binding (238..634): val
NRPSPredictor2: val
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
val
Stachelhaus prediction details:
Stachelhaus sequence:
dlvftgsmfk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000003.1 - Region 4 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,965,359 - 2,044,847 nt. (total: 79,489 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 1965358 - 2044847:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (pk) + (X)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 7, location 1965358 - 2019826:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (pk)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 8, location 2001489 - 2044847:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_17790: pk
PKS_AT (544..855): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
CE-Malonyl-CoA: 62.5%
Methylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 69.7
Malonyl-CoA: 60.0
Methoxymalonyl-CoA: 50.7
Propionyl-CoA: 26.4
Isobutyryl-CoA: 25.3
Ethylmalonyl-CoA: 24.0
Acetyl-CoA: 21.4
3-Methylbutyryl-CoA: 21.0
Benzoyl-CoA: 19.5
fatty_acid: 17.4
2-Methylbutyryl-CoA: 17.3
trans-1,2-CPDA: 16.3
CHC-CoA: 14.4
inactive: 11.0


ATCC64974_17810: pk
PKS_AT (582..886): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Propionyl-CoA: 62.5%
2-Methylbutyryl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 94.2
Methoxymalonyl-CoA: 79.4
Malonyl-CoA: 62.9
Ethylmalonyl-CoA: 57.9
Isobutyryl-CoA: 50.1
Propionyl-CoA: 46.8
Benzoyl-CoA: 39.8
fatty_acid: 36.8
trans-1,2-CPDA: 31.8
2-Methylbutyryl-CoA: 21.9
CHC-CoA: 19.8
3-Methylbutyryl-CoA: 11.9
Acetyl-CoA: 5.5
inactive: 0.0


ATCC64974_17890: X
Search NORINE for peptide: strict or relaxed

AMP-binding (24..432): X
NRPSPredictor2: asp, asn, glu, gln, aad
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
iighrgvpak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000003.1 - Region 5 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 3,133,468 - 3,179,948 nt. (total: 46,481 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 9, location 3133467 - 3179948:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_21450: pk
PKS_AT (307..611): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
2-Methylbutyryl-CoA: 62.5%
Methylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 72.1
Malonyl-CoA: 65.4
Methoxymalonyl-CoA: 62.2
Propionyl-CoA: 49.7
Isobutyryl-CoA: 38.5
2-Methylbutyryl-CoA: 34.2
trans-1,2-CPDA: 30.1
Ethylmalonyl-CoA: 30.0
fatty_acid: 16.1
Benzoyl-CoA: 16.1
CHC-CoA: 14.7
inactive: 9.8
3-Methylbutyryl-CoA: 3.9
Acetyl-CoA: 0.0


OGUI01000003.1 - Region 6 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 3,326,754 - 3,348,583 nt. (total: 21,830 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000003.1 - Region 7 - indole
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 4,321,013 - 4,342,463 nt. (total: 21,451 nt) Show pHMM detection rules used
indole: (indsynth or dmat or indole_PTase)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000003.1 - Region 8 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 4,446,876 - 4,499,853 nt. (total: 52,978 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 12, location 4446875 - 4499853:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 13, location 4446875 - 4492711:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 14, location 4460016 - 4499853:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_25470: pk
PKS_AT (540..849): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 87.5%
Methylmalonyl-CoA: 70.8%
Ethylmalonyl-CoA: 62.5%

minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 73.2
Methylmalonyl-CoA: 72.4
Malonyl-CoA: 64.7
Ethylmalonyl-CoA: 50.6
Isobutyryl-CoA: 43.7
Propionyl-CoA: 43.3
inactive: 25.0
2-Methylbutyryl-CoA: 24.2
trans-1,2-CPDA: 20.0
Benzoyl-CoA: 14.9
CHC-CoA: 12.4
fatty_acid: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


ATCC64974_25490: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (29..418): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hllmyavlik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000003.1 - Region 9 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 4,543,231 - 4,613,882 nt. (total: 70,652 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 15, location 4543230 - 4613882:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(phe) + (pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_25750: pk - X
Search NORINE for peptide: strict or relaxed

PKS_AT (547..865): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 76.5
Methoxymalonyl-CoA: 69.0
Ethylmalonyl-CoA: 43.4
Malonyl-CoA: 38.3
Propionyl-CoA: 33.8
Benzoyl-CoA: 27.6
trans-1,2-CPDA: 26.0
Isobutyryl-CoA: 24.4
fatty_acid: 19.2
CHC-CoA: 11.8
2-Methylbutyryl-CoA: 2.6
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0

AMP-binding (2970..3380): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
didmngcvwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ATCC64974_25800: phe
Search NORINE for peptide: strict or relaxed

AMP-binding (264..666): phe
NRPSPredictor2: phe
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
phe
Stachelhaus prediction details:
Stachelhaus sequence:
dawmfaatfk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000011.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 116,026 - 159,121 nt. (total: 43,096 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 116025 - 159121:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_71910: X
Search NORINE for peptide: strict or relaxed

AMP-binding (25..424): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dtvqiggvyk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000010.1 - Region 1 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 13,744 - 59,107 nt. (total: 45,364 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 13743 - 59107:
Polymer prediction:
(ccmmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_63190: ccmmal
PKS_AT (594..885): ccmmal
ATSignature: Methylmalonyl-CoA, Malonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 75.0%
Malonyl-CoA: 75.0%
Ethylmalonyl-CoA: 70.8%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 111.9
Ethylmalonyl-CoA: 94.8
Methoxymalonyl-CoA: 91.0
Isobutyryl-CoA: 67.1
Malonyl-CoA: 58.2
trans-1,2-CPDA: 46.4
Benzoyl-CoA: 44.0
Propionyl-CoA: 40.9
2-Methylbutyryl-CoA: 40.5
Acetyl-CoA: 31.8
fatty_acid: 30.0
CHC-CoA: 16.5
3-Methylbutyryl-CoA: 16.1
inactive: 10.4


OGUI01000010.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 408,816 - 429,775 nt. (total: 20,960 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000010.1 - Region 3 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,631,408 - 1,692,712 nt. (total: 61,305 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 1631407 - 1692712:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(leu - X - ala - hydrophobic-aliphatic - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_68020: leu - X - ala - hydrophobic-aliphatic - X
Search NORINE for peptide: strict or relaxed

AMP-binding (40..446): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dvsdvgpptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1698..2093): X
NRPSPredictor2: orn, lys, arg
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
orn, lys, arg
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvsdvgpptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3245..3649): ala
NRPSPredictor2: ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
gly, ala
Single AA prediction:
ala
Stachelhaus prediction details:
Stachelhaus sequence:
dvcihiltfk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (4334..4736): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvadtgsptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (5884..6281): X
NRPSPredictor2: orn, lys, arg
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
orn, lys, arg
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvsdvgpptk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000006.1 - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 492,568 - 514,173 nt. (total: 21,606 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000006.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 534,463 - 573,673 nt. (total: 39,211 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 534462 - 573673:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_40610: pk
PKS_AT (1548..1741): pk
ATSignature: (unknown)
No matches above 50%

minowa: trans-1,2-CPDA
Prediction, score:
trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0


ATCC64974_40650: pk
PKS_AT (924..1218): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 62.5%
inactive: 54.2%
Methylmalonyl-CoA: 54.2%

minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 58.4
Malonyl-CoA: 56.4
Methylmalonyl-CoA: 53.8
inactive: 47.3
Propionyl-CoA: 31.9
2-Methylbutyryl-CoA: 27.9
Ethylmalonyl-CoA: 26.2
CHC-CoA: 25.6
trans-1,2-CPDA: 19.5
Benzoyl-CoA: 18.9
Isobutyryl-CoA: 17.6
fatty_acid: 17.1
3-Methylbutyryl-CoA: 9.3
Acetyl-CoA: 8.6


OGUI01000006.1 - Region 3 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 659,225 - 762,440 nt. (total: 103,216 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 659224 - 762440:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(hydrophobic-aliphatic - hydrophobic-aliphatic - X - X) + (X) + (pk) + (redmmal)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 4, location 659224 - 728956:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X) + (pk) + (redmmal)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 5, location 692502 - 762440:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (X) + (hydrophobic-aliphatic - hydrophobic-aliphatic - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_41130: redmmal
PKS_AT (550..849): redmmal
ATSignature: Methylmalonyl-CoA, Malonyl-CoA
Top 3 matches:
Methylmalonyl-CoA: 75.0%
Malonyl-CoA: 75.0%
Isobutyryl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 84.4
Malonyl-CoA: 69.9
Methoxymalonyl-CoA: 69.7
Isobutyryl-CoA: 60.6
Ethylmalonyl-CoA: 52.8
Benzoyl-CoA: 43.4
Propionyl-CoA: 37.8
fatty_acid: 21.1
trans-1,2-CPDA: 20.6
2-Methylbutyryl-CoA: 18.9
Acetyl-CoA: 15.2
CHC-CoA: 11.8
inactive: 10.6
3-Methylbutyryl-CoA: 0.0


ATCC64974_41180: pk
PKS_AT (539..859): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 85.8
Methoxymalonyl-CoA: 77.2
Isobutyryl-CoA: 58.7
Ethylmalonyl-CoA: 52.2
Malonyl-CoA: 47.9
fatty_acid: 29.3
Propionyl-CoA: 23.7
Benzoyl-CoA: 22.8
inactive: 15.7
trans-1,2-CPDA: 13.9
2-Methylbutyryl-CoA: 11.6
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


ATCC64974_41200: X
Search NORINE for peptide: strict or relaxed

AMP-binding (20..455): X
NRPSPredictor2: phe, trp
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
phe, trp
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
vlmvislfck
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ATCC64974_41280: hydrophobic-aliphatic - hydrophobic-aliphatic - X - X
Search NORINE for peptide: strict or relaxed

AMP-binding (224..616): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmlicgfink
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1326..1716): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
daamaigimk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2500..2894): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
damfgglivk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (4046..4443): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dawfvgailk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000006.1 - Region 4 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 939,193 - 995,685 nt. (total: 56,493 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 939192 - 995685:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - pro - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_42010: X - pro - X - X
Search NORINE for peptide: strict or relaxed

AMP-binding (225..634): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvlfaggvak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1784..2182): pro
NRPSPredictor2: pro
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
pro, pip
Small clusters prediction:
pro
Single AA prediction:
pro
Stachelhaus prediction details:
Stachelhaus sequence:
dtqhfasvak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2877..3274): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvsfagsiwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3957..4353): X
NRPSPredictor2: gly, ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
gly, ala
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
digsvgiiyk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000016.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 41,840 - 91,296 nt. (total: 49,457 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 41839 - 91296:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(hydrophobic-aliphatic - X - hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_87000: hydrophobic-aliphatic - X - hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (238..633): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
vmaivavgak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1395..1801): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dmwmfaavlk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2480..2852): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dawfvgt--k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000016.1 - Region 2 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 106,598 - 157,663 nt. (total: 51,066 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 106597 - 157663:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk - hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_87180: pk - hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

PKS_AT (566..879): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 62.5%
Isobutyryl-CoA: 54.2%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 88.5
Methoxymalonyl-CoA: 85.2
Isobutyryl-CoA: 79.1
Malonyl-CoA: 68.2
Ethylmalonyl-CoA: 47.5
Propionyl-CoA: 45.7
Benzoyl-CoA: 39.1
inactive: 38.5
3-Methylbutyryl-CoA: 30.4
trans-1,2-CPDA: 26.0
2-Methylbutyryl-CoA: 24.2
Acetyl-CoA: 23.4
CHC-CoA: 11.7
fatty_acid: 10.7

AMP-binding (2856..3269): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dlvylatvqk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000016.1 - Region 3 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 663,434 - 683,094 nt. (total: 19,661 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000016.1 - Region 4 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 942,909 - 989,501 nt. (total: 46,593 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 942908 - 989501:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_89800: pk
PKS_AT (533..838): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 70.8
Methoxymalonyl-CoA: 65.2
Malonyl-CoA: 41.9
Isobutyryl-CoA: 35.6
Propionyl-CoA: 23.4
Benzoyl-CoA: 20.5
trans-1,2-CPDA: 19.5
3-Methylbutyryl-CoA: 19.5
fatty_acid: 15.9
inactive: 9.8
2-Methylbutyryl-CoA: 3.7
CHC-CoA: 0.0
Acetyl-CoA: 0.0
Ethylmalonyl-CoA: -3.2


OGUI01000016.1 - Region 5 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,011,287 - 1,051,842 nt. (total: 40,556 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 1011286 - 1051842:
Polymer prediction:
(redmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_90000: redmal
PKS_AT (597..933): redmal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 70.8%
Ethylmalonyl-CoA: 62.5%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 92.7
Methylmalonyl-CoA: 80.4
Methoxymalonyl-CoA: 79.0
Isobutyryl-CoA: 60.1
Ethylmalonyl-CoA: 50.6
Propionyl-CoA: 39.6
Benzoyl-CoA: 24.1
3-Methylbutyryl-CoA: 23.3
inactive: 23.1
fatty_acid: 18.5
2-Methylbutyryl-CoA: 12.8
trans-1,2-CPDA: 8.8
CHC-CoA: 5.5
Acetyl-CoA: 0.0


OGUI01000016.1 - Region 6 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,115,792 - 1,160,889 nt. (total: 45,098 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 1115791 - 1160889:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_90360: pk
PKS_AT (546..860): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 87.5
Methoxymalonyl-CoA: 83.3
Isobutyryl-CoA: 63.9
Ethylmalonyl-CoA: 60.4
Malonyl-CoA: 59.2
Propionyl-CoA: 30.1
Benzoyl-CoA: 29.3
fatty_acid: 26.5
trans-1,2-CPDA: 23.4
Acetyl-CoA: 22.8
inactive: 20.9
CHC-CoA: 17.8
3-Methylbutyryl-CoA: 17.5
2-Methylbutyryl-CoA: 15.0


OGUI01000016.1 - Region 7 - NRPS-like,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,404,466 - 1,474,010 nt. (total: 69,545 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 7, location 1404465 - 1474010:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk) + (X)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 8, location 1404465 - 1446257:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed
For candidate cluster 9, location 1427990 - 1474010:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_91290: X
Search NORINE for peptide: strict or relaxed

AMP-binding (88..350): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
nhsymgh--k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ATCC64974_91360: pk
PKS_AT (540..844): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 70.8%
Methylmalonyl-CoA: 58.3%
Propionyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 66.2
Methoxymalonyl-CoA: 55.6
Propionyl-CoA: 51.2
2-Methylbutyryl-CoA: 26.7
CHC-CoA: 26.2
Benzoyl-CoA: 22.9
fatty_acid: 19.9
trans-1,2-CPDA: 17.2
Ethylmalonyl-CoA: 16.7
Malonyl-CoA: 10.1
Isobutyryl-CoA: 8.7
inactive: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


OGUI01000016.1 - Region 8 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,593,494 - 1,614,255 nt. (total: 20,762 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000016.1 - Region 9 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,618,876 - 1,670,895 nt. (total: 52,020 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 11, location 1618875 - 1670895:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk - leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_92040: pk - leu
Search NORINE for peptide: strict or relaxed

PKS_AT (551..867): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 62.5%
Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 57.2
Methoxymalonyl-CoA: 48.5
Malonyl-CoA: 26.6
Propionyl-CoA: 24.2
Benzoyl-CoA: 21.3
Ethylmalonyl-CoA: 20.9
Isobutyryl-CoA: 19.8
inactive: 18.3
fatty_acid: 13.8
trans-1,2-CPDA: 8.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

AMP-binding (2954..3356): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dafllgavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000016.1 - Region 10 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 1,792,562 - 1,837,943 nt. (total: 45,382 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 12, location 1792561 - 1837943:
Polymer prediction:
(mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_92700: mal
PKS_AT (925..1226): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 75.0%
inactive: 70.8%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 93.9
Methylmalonyl-CoA: 67.5
inactive: 60.7
Methoxymalonyl-CoA: 51.9
Ethylmalonyl-CoA: 32.4
Isobutyryl-CoA: 30.1
Acetyl-CoA: 29.3
Benzoyl-CoA: 28.4
Propionyl-CoA: 26.4
2-Methylbutyryl-CoA: 21.1
fatty_acid: 20.9
3-Methylbutyryl-CoA: 17.5
CHC-CoA: 16.9
trans-1,2-CPDA: 13.1


OGUI01000005.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 6,341 - 46,336 nt. (total: 39,996 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 6340 - 46336:
Polymer prediction:
(hydrophobic-aliphatic)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_33140: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (38..434): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hlvicgavik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000005.1 - Region 2 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 62,914 - 83,693 nt. (total: 20,780 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000005.1 - Region 3 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 207,540 - 245,588 nt. (total: 38,049 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 207539 - 245588:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_33860: X
Search NORINE for peptide: strict or relaxed

AMP-binding (20..423): X
NRPSPredictor2: phe, trp, phg, tyr, bht
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aromatic
Large clusters prediction:
phe, trp, phg, tyr, bht
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hmllygaiik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000005.1 - Region 4 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 833,288 - 885,350 nt. (total: 52,063 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 833287 - 885350:
Polymer prediction:
(hydrophobic-aliphatic - hydrophobic-aliphatic - hydrophilic)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_35710: hydrophobic-aliphatic - hydrophobic-aliphatic - hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (516..922): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dianmgnfvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1598..1999): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dawlvgavik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3139..3550): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dagsvggiek
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000005.1 - Region 5 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 886,405 - 933,218 nt. (total: 46,814 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 886404 - 933218:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_35860: pk
PKS_AT (555..863): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 87.5%
Methylmalonyl-CoA: 66.7%
Ethylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 92.0
Methoxymalonyl-CoA: 89.2
Malonyl-CoA: 87.1
Isobutyryl-CoA: 75.0
Ethylmalonyl-CoA: 66.3
Benzoyl-CoA: 40.2
Propionyl-CoA: 35.2
2-Methylbutyryl-CoA: 30.9
trans-1,2-CPDA: 29.2
inactive: 28.8
Acetyl-CoA: 25.0
fatty_acid: 15.6
CHC-CoA: 13.5
3-Methylbutyryl-CoA: 10.6


OGUI01000007.1 - Region 1 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 2,239 - 42,045 nt. (total: 39,807 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 2238 - 42045:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(hydrophobic-aliphatic) + (pk - leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_43040: pk - leu
Search NORINE for peptide: strict or relaxed

PKS_AT (568..884): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
Methylmalonyl-CoA: 66.7%
2-Methylbutyryl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 66.7
Methoxymalonyl-CoA: 59.4
Ethylmalonyl-CoA: 38.6
Propionyl-CoA: 31.7
Isobutyryl-CoA: 23.0
Benzoyl-CoA: 20.1
3-Methylbutyryl-CoA: 14.0
2-Methylbutyryl-CoA: 13.6
fatty_acid: 13.3
inactive: 11.2
Malonyl-CoA: 10.7
trans-1,2-CPDA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0

AMP-binding (2826..3235): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
daalmgavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


ATCC64974_43080: hydrophobic-aliphatic
Search NORINE for peptide: strict or relaxed

AMP-binding (29..466): hydrophobic-aliphatic
NRPSPredictor2: hydrophobic-aliphatic
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
gllvigcpik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000007.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 191,511 - 231,900 nt. (total: 40,390 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 191510 - 231900:
Polymer prediction:
(mmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_43830: mmal
PKS_AT (548..848): mmal
ATSignature: Malonyl-CoA, Isobutyryl-CoA, Methylmalonyl-CoA
Top 3 matches:
Malonyl-CoA: 62.5%
Isobutyryl-CoA: 62.5%
Methylmalonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 78.3
Methoxymalonyl-CoA: 71.8
Isobutyryl-CoA: 67.3
Malonyl-CoA: 47.0
Ethylmalonyl-CoA: 43.1
Propionyl-CoA: 36.4
2-Methylbutyryl-CoA: 31.0
Benzoyl-CoA: 27.2
trans-1,2-CPDA: 22.6
3-Methylbutyryl-CoA: 20.7
CHC-CoA: 18.0
fatty_acid: 15.6
inactive: 10.4
Acetyl-CoA: 0.0


OGUI01000007.1 - Region 3 - indole
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 544,845 - 566,044 nt. (total: 21,200 nt) Show pHMM detection rules used
indole: (indsynth or dmat or indole_PTase)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000007.1 - Region 4 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 3,435,564 - 3,456,894 nt. (total: 21,331 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000007.1 - Region 5 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 3,650,920 - 3,672,640 nt. (total: 21,721 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 3650919 - 3672640:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_54520: X
Search NORINE for peptide: strict or relaxed

AMP-binding (25..443): X
NRPSPredictor2: glu, gln
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
asp, asn, glu, gln, aad
Small clusters prediction:
glu, gln
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
vgefvggagk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000007.1 - Region 6 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 3,827,210 - 3,866,100 nt. (total: 38,891 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 3827209 - 3866100:
Polymer prediction:
(redmmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_54900: redmmal
PKS_AT (554..856): redmmal
ATSignature: Malonyl-CoA, Methylmalonyl-CoA
Top 3 matches:
Malonyl-CoA: 66.7%
Methylmalonyl-CoA: 66.7%
CE-Malonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 71.0
Methoxymalonyl-CoA: 67.0
Malonyl-CoA: 36.4
Propionyl-CoA: 34.7
Ethylmalonyl-CoA: 31.5
trans-1,2-CPDA: 31.1
fatty_acid: 25.3
2-Methylbutyryl-CoA: 21.4
CHC-CoA: 16.9
Isobutyryl-CoA: 15.8
Benzoyl-CoA: 15.6
Acetyl-CoA: 8.4
inactive: 0.0
3-Methylbutyryl-CoA: 0.0


OGUI01000007.1 - Region 7 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 4,149,058 - 4,201,157 nt. (total: 52,100 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 7, location 4149057 - 4201157:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(pk - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_55920: pk - X
Search NORINE for peptide: strict or relaxed

PKS_AT (580..895): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 79.2%
Methylmalonyl-CoA: 66.7%
2-Methylbutyryl-CoA: 58.3%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 74.7
Methoxymalonyl-CoA: 63.7
Malonyl-CoA: 45.8
Isobutyryl-CoA: 40.4
Benzoyl-CoA: 34.8
Ethylmalonyl-CoA: 31.7
Propionyl-CoA: 25.9
3-Methylbutyryl-CoA: 19.9
fatty_acid: 15.8
Acetyl-CoA: 14.7
inactive: 14.0
trans-1,2-CPDA: 11.1
CHC-CoA: 9.3
2-Methylbutyryl-CoA: 7.2

AMP-binding (2943..3328): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
daftfvamak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000007.1 - Region 8 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 4,981,815 - 5,027,524 nt. (total: 45,710 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 8, location 4981814 - 5027524:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_58440: X
Search NORINE for peptide: strict or relaxed

AMP-binding (222..614): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvlevgavvk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000008.1 - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 97,739 - 139,456 nt. (total: 41,718 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 97738 - 139456:
Polymer prediction:
(ala)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_59190: ala
Search NORINE for peptide: strict or relaxed

AMP-binding (13..412): ala
NRPSPredictor2: ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
ala
Stachelhaus prediction details:
Stachelhaus sequence:
nvwlwnceik
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000008.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 141,129 - 189,697 nt. (total: 48,569 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 141128 - 189697:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_59380: pk
PKS_AT (551..866): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 83.3%
Methylmalonyl-CoA: 70.8%
Ethylmalonyl-CoA: 66.7%

minowa: Methylmalonyl-CoA
Prediction, score:
Methylmalonyl-CoA: 74.2
Methoxymalonyl-CoA: 64.2
Malonyl-CoA: 54.0
Isobutyryl-CoA: 46.5
Ethylmalonyl-CoA: 29.3
Propionyl-CoA: 27.0
2-Methylbutyryl-CoA: 12.9
fatty_acid: 12.2
Benzoyl-CoA: 10.7
trans-1,2-CPDA: 9.7
inactive: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


OGUI01000008.1 - Region 3 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 227,395 - 270,714 nt. (total: 43,320 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 227394 - 270714:
Polymer prediction:
(X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_59630: X
Search NORINE for peptide: strict or relaxed

AMP-binding (70..353): X
NRPSPredictor2: (unknown)
SVM prediction details:
Predicted physicochemical class:
N/A
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
hlsq--t--k
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000014.1 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 2,398 - 40,016 nt. (total: 37,619 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 2397 - 40016:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(X - X - X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_82390: X - X - X - X - X
Search NORINE for peptide: strict or relaxed

AMP-binding (234..634): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dallfgavlk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1327..1735): X
NRPSPredictor2: gly, ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
gly, ala
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvgcvgivwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (2422..2818): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvafvgsiwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (3506..3905): X
NRPSPredictor2: gly, ala
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
gly, ala
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvgcvgiiwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (4559..4954): X
NRPSPredictor2: val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvgcsgiiwk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000014.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 55,072 - 94,019 nt. (total: 38,948 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 55071 - 94019:
Polymer prediction:
(mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_82540: mal
PKS_AT (928..1207): mal
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 58.3%

minowa: Malonyl-CoA
Prediction, score:
Malonyl-CoA: 57.9
inactive: 36.3
Methylmalonyl-CoA: 33.4
Methoxymalonyl-CoA: 30.5
Ethylmalonyl-CoA: 18.1
fatty_acid: 15.3
Benzoyl-CoA: 12.6
CHC-CoA: 12.5
trans-1,2-CPDA: 11.2
Isobutyryl-CoA: 11.0
Propionyl-CoA: 9.8
2-Methylbutyryl-CoA: 9.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0


OGUI01000014.1 - Region 3 - NRPS,terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 162,864 - 207,807 nt. (total: 44,944 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 162863 - 207807:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account
Polymer prediction:
(leu - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_82970: leu - X
Search NORINE for peptide: strict or relaxed

AMP-binding (34..430): leu
NRPSPredictor2: leu
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
val, leu, ile, abu, iva
Single AA prediction:
leu
Stachelhaus prediction details:
Stachelhaus sequence:
dalfigavak
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)

AMP-binding (1152..1554): X
NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
SVM prediction details:
Predicted physicochemical class:
hydrophobic-aliphatic
Large clusters prediction:
gly, ala, val, leu, ile, abu, iva
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
digsvamiyk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)


OGUI01000014.1 - Region 4 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 213,401 - 236,481 nt. (total: 23,081 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
ClusterBlast
KnownClusterBlast
SubClusterBlast
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).

No significant ClusterBlast hits found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

OGUI01000014.1 - Region 5 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 386,452 - 432,916 nt. (total: 46,465 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 386451 - 432916:
Polymer prediction:
(pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_83740: pk
PKS_AT (904..1193): pk
ATSignature: Malonyl-CoA
Top 3 matches:
Malonyl-CoA: 62.5%
Ethylmalonyl-CoA: 54.2%
inactive: 54.2%

minowa: Methoxymalonyl-CoA
Prediction, score:
Methoxymalonyl-CoA: 55.9
Malonyl-CoA: 52.1
Methylmalonyl-CoA: 50.1
inactive: 42.6
Ethylmalonyl-CoA: 36.3
Propionyl-CoA: 27.4
CHC-CoA: 27.2
Acetyl-CoA: 25.9
fatty_acid: 23.0
2-Methylbutyryl-CoA: 20.6
trans-1,2-CPDA: 20.3
Benzoyl-CoA: 16.3
Isobutyryl-CoA: 16.2
3-Methylbutyryl-CoA: 11.0


OGUI01000014.1 - Region 6 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Location: 721,124 - 767,332 nt. (total: 46,209 nt) Show pHMM detection rules used
NRPS: (cds(Condensation and (AMP-binding or A-OX)) or (Condensation and AMP-binding))

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
other genes
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
ClusterBlast
KnownClusterBlast
SubClusterBlast
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Similar gene clusters
Shows clusters from the antiSMASH database and other clusters of interest that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the antiSMASH database (if applicable).
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 7, location 721123 - 767332:
Polymer prediction:
(hydrophilic)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
ATCC64974_84880: hydrophilic
Search NORINE for peptide: strict or relaxed

AMP-binding (199..603): hydrophilic
NRPSPredictor2: hydrophilic
SVM prediction details:
Predicted physicochemical class:
hydrophilic
Large clusters prediction:
N/A
Small clusters prediction:
N/A
Single AA prediction:
N/A
Stachelhaus prediction details:
Stachelhaus sequence:
dvdggggigk
Nearest Stachelhaus code:
N, A
Stachelhaus code match:
0% (weak)