LOCUS       OGUI01000007.1         21721 bp    DNA     linear   PLN 19-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   OGUI01000007
VERSION     OGUI01000007.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 07:37:12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3650919
            Orig. end    :: 3672640
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21721
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[3663024:3665811](+)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      12106..14892
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..21721
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21721
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS-like"
                     /region_number="5"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     mRNA            complement(join(1..716,793..857,919..981,1045..1067))
                     /locus_tag="ATCC64974_54470"
                     /product="hypothetical protein"
     gene            complement(1..1067)
                     /locus_tag="ATCC64974_54470"
     CDS             complement(join(1..716,793..857,919..981,1045..1067))
                     /codon_start=1
                     /db_xref="InterPro:IPR007590"
                     /db_xref="PFAM:PF04502"
                     /locus_tag="ATCC64974_54470"
                     /note="BUSCO:EOG092655M5; EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_54470-T1"
                     /transl_table=1
                     /translation="MSERKVLTKYYPPDFDPSAITRTPKHLRQQGPKVITVRLMAPFSM
                     KCTKCGEFIYKGRKFNARKETTSEKYFSIPIYRFYIRCTRCSGEITFLTDPKNMDYRAE
                     RGAKRNFEPWRDRSKAEETAEETEEQVLDRLEREEGENMEQEERDKMAELEEKMLDSKR
                     EMAIADALDEIRTRNARIERGGAGGEVALGAVREEKDEEAERVEREIEEVARRAFRTEE
                     GEKVRRLVEDDESPDSGVGGSGNVAASGSGAGEMPPPPPSFARVKKAKKPAVNSLGIKK
                     KAKPSLV"
     mRNA            complement(join(1390..3584,3641..3737))
                     /locus_tag="ATCC64974_54480"
                     /product="hypothetical protein"
     gene            complement(1390..3737)
                     /locus_tag="ATCC64974_54480"
     CDS             complement(join(1390..3584,3641..3737))
                     /codon_start=1
                     /db_xref="InterPro:IPR011990"
                     /db_xref="InterPro:IPR013026"
                     /db_xref="InterPro:IPR019734"
                     /db_xref="PFAM:PF12895"
                     /db_xref="PFAM:PF13374"
                     /db_xref="PFAM:PF13432"
                     /gene_functions="other (smcogs) SMCOG1272:TPR
                     repeat-containing protein (Score: 61.6; E-value: 1.1e-18)"
                     /gene_kind="other"
                     /locus_tag="ATCC64974_54480"
                     /note="BUSCO:EOG09260S5R; GO_function: GO:0005515 - protein
                     binding [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_54480-T1"
                     /transl_table=1
                     /translation="MEKFLRSWRQDALNRGQHDAAIYIGDKVLALTNSDSDAFWLAQVH
                     FSNNNYARALALLSRKDLISRSTACRYLAAHCHIKQNQFDQALSVLGDHNPTHLIRSSN
                     SRRKIQHLNGQSHVTLRNGKTTASRIDRGEEREREDANNVRFEAAMCYLRGLCFAKQNA
                     FDRARDCYKDAVRIDVQCFEAFDQLMKNSLMSPAEELEFLESLDFDSVSSPDQSVAQEA
                     AHFTKMLYTTRLSKYSSPTILSDATETLSTHYNLAENPDILLSRAEALYTQCRFAEALE
                     LTSSVLSTSQSAVSSQMTPAVHISAQSHLGHPPAVYPLHLACLYETGATNALFLLSHTL
                     ADHAPEESYTYLAIGVYYLSVSKIAEARRYFSKASLLDPHSAPAWIGFAHTFAAEGEHD
                     QAIAAYSTAARLFQGSHLPQLFLGMQHLALNNMSLAHEYLSAAYSMSTGSASSSAPSIR
                     ANPSELTSLGGDPLVLNELGVVLYHQNHLEGAVELFRQSLTLATSLQCEPGAWVATRAN
                     LGHALRRIGQFQESLAEFDECLRIGAAGASFGYSPFLGGSGGNASGVASSGVGGYEDRG
                     LIGSLHTARGLVLLELNRTMEAVTALHEAVRVLGASGGGDAAGGAGIAGTLLSRALEIW
                     ALEGQEEPVVLEDARITTSRSSTRSSKGKGKVSRRRGTVDEAYAEEWTDEVAHVDSQTT
                     VTEETAGDKVEMELDDEADGLLRHAMSRVRGGRSKRQPGLSRDMEMNDTPGPAGGRSRG
                     SRMRSNARHS"
     mRNA            complement(join(4209..5131,5187..5208))
                     /locus_tag="ATCC64974_54490"
                     /product="hypothetical protein"
     gene            complement(4209..5208)
                     /locus_tag="ATCC64974_54490"
     CDS             complement(join(4209..5131,5187..5208))
                     /codon_start=1
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="InterPro:IPR036259"
                     /db_xref="PFAM:PF07690"
                     /gene_functions="transport (smcogs) SMCOG1137:Major
                     facilitator superfamily MFS 1 (Score: 221.7; E-value:
                     2.1e-67)"
                     /gene_kind="transport"
                     /locus_tag="ATCC64974_54490"
                     /note="EggNog:ENOG41; GO_component: GO:0005887 - integral
                     component of plasma membrane [Evidence IEA]; GO_process:
                     GO:0055085 - transmembrane transport [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_54490-T1"
                     /transl_table=1
                     /translation="MFLSVSHEYYQFILGFSILGGLSASAVYTPSAACITHWFLKRRGL
                     ATGIATTGGGIGGIIFTNVFGILSNKIGFPWTIRILGFIFLASLMVSLLTLEARLPPSP
                     SAGNKIDIRALKEPVFTMTSIAVIFAEIGLIVLVTYYPSYAQSHGITGALSYQLMTIMS
                     ATSIFGRVIPGVLADIWGRFNVMFGTCAVCTILSFGLWFTAGTDKACILAFAALVGFWS
                     GPAISLTPVCVAQISKTESYGKRFGTTIALMAFALLVAIPVAGEILKGQNRGKVETEYS
                     GLIGFSGAAYAGACLFLFLAKGASVGWRVTKVF"
     mRNA            complement(join(6667..6822,7032..7455,7811..7883,
                     7942..8047,8106..8190,8246..8314,8383..8456))
                     /locus_tag="ATCC64974_54500"
                     /product="hypothetical protein"
     gene            complement(6667..8456)
                     /locus_tag="ATCC64974_54500"
     CDS             complement(join(6667..6822,7032..7455,7811..7883,
                     7942..8047,8106..8190,8246..8314,8383..8456))
                     /NRPS_PKS="Domain: Aminotran_1_2 (38-280). E-value:
                     2.5e-28. Score: 90.9. Matches aSDomain:
                     nrpspksdomains_ATCC64974_54500_Aminotran_1_2.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="InterPro:IPR004839"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 132.1; E-value:
                     4.2e-40)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC64974_54500"
                     /note="GO_function: GO:0030170 - pyridoxal phosphate
                     binding [Evidence IEA]; GO_function: GO:0003824 - catalytic
                     activity [Evidence IEA]; GO_process: GO:0009058 -
                     biosynthetic process [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_54500-T1"
                     /transl_table=1
                     /translation="MEARSSSGSFSTPAPRVASDRLDVWSIVNEAAAISPIQPIVNLGQ
                     GFFGFNPPQFAIDAAKEALNRVDCNQCAPTKGRLSLRKAIASAYSKLLERPIDEENEVT
                     ITSGANEGMLCALLAFIHPGDEVVTFEPFFDHHNPVGKVFTETELQRIGDFCLKHDLLI
                     LSDEVYDHLYYVPFTRIATISPDLYDHTLTVASAGKAFHATGWRIGYLIGPQQLIKYVS
                     AVHTRICYSSVSPLQEAVAVAFEAADRNGFWEHSRQEMKDKMRLFCEVFEDLGLPEIGV
                     AAIPPSEFYSDDNAHIGEDFLRFAFCKEDEVLEMGKQRLLRLKSYIV"
     aSDomain        complement(join(6814..6822,7032..7455,7811..7883,
                     7942..8047,8106..8190,8246..8274))
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC64974_54500_Aminotran_1_2.1"
                     /evalue="2.50E-28"
                     /label="ATCC64974_54500_Aminotran_1_2.1"
                     /locus_tag="ATCC64974_54500"
                     /score="90.9"
                     /tool="antismash"
                     /translation="PIVNLGQGFFGFNPPQFAIDAAKEALNRVDCNQCAPTKGRLSLRK
                     AIASAYSKLLERPIDEENEVTITSGANEGMLCALLAFIHPGDEVVTFEPFFDHHNPVGK
                     VFTETELQRIGDFCLKHDLLILSDEVYDHLYYVPFTRIATISPDLYDHTLTVASAGKAF
                     HATGWRIGYLIGPQQLIKYVSAVHTRICYSSVSPLQEAVAVAFEAADRNGFWEHSRQEM
                     KDKMRLFCEVFEDLGLPEIGV"
     mRNA            complement(join(9298..9846,9911..10405,10467..10765,
                     10818..11166))
                     /locus_tag="ATCC64974_54510"
                     /product="hypothetical protein"
     gene            complement(9298..11166)
                     /locus_tag="ATCC64974_54510"
     CDS             complement(join(9298..9846,9911..10405,10467..10765,
                     10818..11166))
                     /codon_start=1
                     /db_xref="InterPro:IPR003673"
                     /db_xref="InterPro:IPR023606"
                     /db_xref="PFAM:PF02515"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189:L-carnitine dehydratase/bile acid-inducible
                     (Score: 129.1; E-value: 3.1e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC64974_54510"
                     /note="EggNog:ENOG41; GO_function: GO:0008410 -
                     CoA-transferase activity [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_54510-T1"
                     /transl_table=1
                     /translation="MYRPSEEARRIYDLLCQNSERLGLPSEIYSSRVQFQANSDTIYYP
                     IPFKVTETLAALKGIEGALAALIADLQSASKPHERKTTINLERATLFGFQALAAKINGY
                     SRSDPKVKRYMKDTDIHAAQSNPYRRMAASMYRTKHDNEFFHLHGSLNPTSTLKMLGLD
                     SHRADLTDYDEIINTIQSQVQKFSAAELERLNETNRQAGVTVYEYEEFKNTPHGRTNIE
                     EPWWKVMRLPGKTPPAAFNPSGSHRILEGVKVLELCCVIAGPMIGRTLAEYGADVLKVT
                     SPTVPDVPFFQVDNNMGKRAVELDLKADEDRRHFEALLADVDVIIDGYRPGALRKLGYS
                     PETVAAMAEKRGKGIVYIDETCFGHEGEWCHRPGWQQIADCLTGFARCHGRFLGRAAEP
                     MVSPLPIADSGAGCMGAIAALTGLYNRIRYGGSYIGQVSLMQFNLLLFAVGQYPNSTES
                     QLQHAFAPAFSKLRFCDSVGRSSVLALEVMRERFPHLFVEPSPGDRQNSLTEIWYSHHY
                     GADVEVVRPVAEIEGVENGFARATRPNGADASPSWDFPQEQGSRKL"
     mRNA            12106..14892
                     /locus_tag="ATCC64974_54520"
                     /product="hypothetical protein"
     gene            12106..14892
                     /locus_tag="ATCC64974_54520"
     CDS             12106..14892
                     /NRPS_PKS="Domain: AMP-binding (25-443). E-value: 1.7e-58.
                     Score: 189.8. Matches aSDomain:
                     nrpspksdomains_ATCC64974_54520_AMP-binding.1"
                     /NRPS_PKS="Domain: ACP (578-644). E-value: 2.4e-07. Score:
                     22.7. Matches aSDomain:
                     nrpspksdomains_ATCC64974_54520_ACP.1"
                     /NRPS_PKS="Domain: Thioesterase (665-913). E-value:
                     4.4e-28. Score: 90.9. Matches aSDomain:
                     nrpspksdomains_ATCC64974_54520_Thioesterase.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /codon_start=1
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001031"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR020806"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="InterPro:IPR036736"
                     /db_xref="InterPro:IPR042099"
                     /db_xref="PFAM:PF00501"
                     /db_xref="PFAM:PF00550"
                     /db_xref="PFAM:PF00975"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     226.4; E-value: 9e-69)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ATCC64974_54520"
                     /note="EggNog:ENOG41; GO_function: GO:0031177 -
                     phosphopantetheine binding [Evidence IEA]; GO_function:
                     GO:0016788 - hydrolase activity, acting on ester bonds
                     [Evidence IEA]; GO_function: GO:0003824 - catalytic
                     activity [Evidence IEA]; GO_process: GO:0009058 -
                     biosynthetic process [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_54520-T1"
                     /sec_met_domain="AMP-binding (E-value: 2.6e-60, bitscore:
                     200.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.5e-12, bitscore:
                     43.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTVNSITDILRKAADHQEPRGVCAYSTGIAGIGSATRLSYTELDS
                     LATSNAILLGRLQCDTESPVILLHFEDHLDNIIWFWSTLYAGYIPAMSTALPRSEEHRT
                     RHLCHLSELFDKPICLTRKTLQNLLTRESPLHVVAIESLNGSSAEFVATTEAISRAPVN
                     SGGGHPALLMLTSGSTGLPKTVSLTHNQILASLQGKSHSLCVEDTGDSFLNWIRLDHVG
                     SFIEIHLHALFVGYDQVHVPPNEIISRPALFLDLISRHRVVRTFAPNFFLAEVGRYLET
                     SQGEDRPHFDLRCLRYIVSGGEAVVASTCAKVSRLLVQHGAPENVIVPGFGMTETCAGC
                     IYNLEFPAFDTRNENEFASLGKCVPGVQARIVSIATGDSPAALGEEGQLELRGPLVFSG
                     YYNNQAATSEAIGPDGWFRTGDTGYIGAGGRINLSGRTKELIAVNGVKYVPHQLEAAIE
                     EASIPGIVSGCVICFSFRPKGAETERPCVIYQHTYCVNDAKARYQTMTAISHRITMITN
                     MRPYILPLQTVKRTSLGKLPRSSLQREVASGQYKMKEAIDREMIKKYRQAIFRPPESPT
                     EKVIVEELSELLSLPQEDIGIDTDLFELGLTSLTLIRLQQALRTRLSLNEPIPLATMIA
                     HNTVRGLFEACQQHHQYIPAVKLQSSGNKTPLWLVHPAAGEALIFINIAKLITDRPVYA
                     FRARGFHHNEPYFTSIDECIRTYHSSMKKLQPHGPYAILGYSYGTMLAFELAKSLEKAG
                     DQVQYLAGLNRPPYVSPVLKRVTWTDCLVNISYFLGLLSRDSYRTLLREISVFPKHDAL
                     ARVIEKVDPGQLLALGLDEGSLEQWINVAFSLQEIGREYEPRGVVNAHMDVFHCTPLEF
                     LNVTPEEWKRRLAAWENFSRQKVNLRHVPGDHANVLGPDHVQVFVKKLGEAMALQGL"
     aSDomain        12181..13434
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC64974_54520_AMP-binding.1"
                     /evalue="1.70E-58"
                     /label="ATCC64974_54520_AMP-binding.1"
                     /locus_tag="ATCC64974_54520"
                     /score="189.8"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="STGIAGIGSATRLSYTELDSLATSNAILLGRLQCDTESPVILLHF
                     EDHLDNIIWFWSTLYAGYIPAMSTALPRSEEHRTRHLCHLSELFDKPICLTRKTLQNLL
                     TRESPLHVVAIESLNGSSAEFVATTEAISRAPVNSGGGHPALLMLTSGSTGLPKTVSLT
                     HNQILASLQGKSHSLCVEDTGDSFLNWIRLDHVGSFIEIHLHALFVGYDQVHVPPNEII
                     SRPALFLDLISRHRVVRTFAPNFFLAEVGRYLETSQGEDRPHFDLRCLRYIVSGGEAVV
                     ASTCAKVSRLLVQHGAPENVIVPGFGMTETCAGCIYNLEFPAFDTRNENEFASLGKCVP
                     GVQARIVSIATGDSPAALGEEGQLELRGPLVFSGYYNNQAATSEAIGPDGWFRTGDTGY
                     IGAGGRINLSGRTKELIAVN"
     CDS_motif       12613..12672
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_54520_0001"
                     /evalue="2.10E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ATCC64974_54520"
                     /score="17.3"
                     /tool="antismash"
                     /translation="ALLMLTSGSTGLPKTVSLTHN"
     aSDomain        13840..14037
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC64974_54520_ACP.1"
                     /evalue="2.40E-07"
                     /label="ATCC64974_54520_ACP.1"
                     /locus_tag="ATCC64974_54520"
                     /score="22.7"
                     /tool="antismash"
                     /translation="VIVEELSELLSLPQEDIGIDTDLFELGLTSLTLIRLQQALRTRLS
                     LNEPIPLATMIAHNTVRGLFEA"
     aSDomain        14101..14844
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC64974_54520_Thioesterase.1"
                     /evalue="4.40E-28"
                     /label="ATCC64974_54520_Thioesterase.1"
                     /locus_tag="ATCC64974_54520"
                     /score="90.9"
                     /tool="antismash"
                     /translation="PLWLVHPAAGEALIFINIAKLITDRPVYAFRARGFHHNEPYFTSI
                     DECIRTYHSSMKKLQPHGPYAILGYSYGTMLAFELAKSLEKAGDQVQYLAGLNRPPYVS
                     PVLKRVTWTDCLVNISYFLGLLSRDSYRTLLREISVFPKHDALARVIEKVDPGQLLALG
                     LDEGSLEQWINVAFSLQEIGREYEPRGVVNAHMDVFHCTPLEFLNVTPEEWKRRLAAWE
                     NFSRQKVNLRHVPGDHANVLGPDHVQV"
     CDS_motif       14278..14352
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_54520_0002"
                     /evalue="7.50E-10"
                     /label="NRPS-te1"
                     /locus_tag="ATCC64974_54520"
                     /score="31.2"
                     /tool="antismash"
                     /translation="QPHGPYAILGYSYGTMLAFELAKSLE"
     mRNA            join(18339..18443,18506..18636,18692..18801,18859..19691,
                     19767..20009)
                     /locus_tag="ATCC64974_54530"
                     /product="hypothetical protein"
     gene            18339..20009
                     /locus_tag="ATCC64974_54530"
     CDS             join(18339..18443,18506..18636,18692..18801,18859..19691,
                     19767..20009)
                     /codon_start=1
                     /db_xref="InterPro:IPR002791"
                     /db_xref="InterPro:IPR036075"
                     /db_xref="PFAM:PF01937"
                     /locus_tag="ATCC64974_54530"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_54530-T1"
                     /transl_table=1
                     /translation="MGLRVNHVITPAGYSTSDESSFAFISAHERWPIILDGIIADVSET
                     LSSTKNSDARAEGLKIIQGFQALKAEIQSDAKLLPLEIDGSTEIVDYNKELAQRKPTWF
                     NVFWLYGECYLYRRIDSLFSQSINWKGYDVFARQKKSTFQSSKTAIVELAARYKTVLST
                     AALKDSTVEAFHFKEMCEICLWGNATDLSLLTSLTYEDIQKLQGAEARKSQEKNVLIND
                     IPVVYDVMNKVRQDKGAGGRVDIVLDNSGFELYVDLLLAAFMLSTGLASKVLLHPKSLP
                     WFVSDVVPADFTDLLMAVSEPESFFGGDIKNKEQETGTVLKEHEKGGLDFLCAQWNAFR
                     KSGKLIVQENPFWITANSYWRLPYIAPGLFGELRESDLVIFKGDLNYRKLTGDVKWDPT
                     TSFSEAIGPLGQGSGVRTLALRTCKADVVVGLAEGQDEGLRNAHHSESAPKERRWAWTG
                     KWAVASFYDGKSIEN"
     mRNA            complement(join(20613..20794,20846..21286,21352..21721))
                     /locus_tag="ATCC64974_54540"
                     /product="hypothetical protein"
     gene            complement(20613..21721)
                     /locus_tag="ATCC64974_54540"
     CDS             complement(join(20613..20794,20846..21286,21352..21721))
                     /codon_start=1
                     /db_xref="InterPro:IPR008775"
                     /db_xref="PFAM:PF05721"
                     /locus_tag="ATCC64974_54540"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_54540-T1"
                     /transl_table=1
                     /translation="MSQILLKAPLRFSHQFQARALSTQLCKLASHPTSIRPSTTEIQNA
                     RLSPQNLEVAMRSLHQDGLVVVENVIPHDSLDRLNAKMTEDAYTLRNKKDGSPFNYNPG
                     NIQQDAPPVRGYFDPQIFLNPIATQITSSALGPRPKWTFCSGNTAMPPTAEHPPMSQPV
                     HSDADFAHPFHPFAYVINVPLITMTPENGSTEVWLGTHTDTGLHVQEGLHGERASGRIK
                     LDELEKRRIERPPCQPTVAKGSLVIRDLRLWHAGIGNQTETPRVMLAMIHFASWYRNPM
                     KLEFADDLKPLIGSQADVEVPCNWVSKSEAMSRYLNRGFGNAYDFSQEP"
ORIGIN
        1 ctataccaac gacggcttcg ccttcttctt gatccccaag ctattcacag caggtttctt
       61 cgctttcttc accctcgcaa acgaaggcgg cggcggcggc atctccccag caccactgcc
      121 gctggcagcg acattcccac tgccacccac cccactatca ggactctcat catcctcaac
      181 caacctccta accttctcgc cctcctccgt cctaaacgcc ctcctcgcca cctcttcaat
      241 ctccctctcc actctctccg cctcctcatc cttctcctcc ctcaccgccc ccaacgccac
      301 ctctccccca gcaccacccc tctcaatcct cgcattccgc gtccttatct catccaacgc
      361 atccgcaatc gccatctccc gcttcgaatc taacatcttc tcctccaact ctgccatctt
      421 atccctttcc tcctgctcca tgttctcccc ttcctcccgc tccaatcgat caagcacctg
      481 ctcctctgtc tcctccgccg tctcctccgc tttgcttctg tcccgccatg gctcgaaatt
      541 gcgcttcgcg ccccgctccg cccggtaatc catgttcttc gggtccgtta ggaaggtgat
      601 ttcgccgctg catcgcgtgc agcggatgta gaagcggtag attgggatgg agaagtattt
      661 ttcggatgtg gtttctttgc gcgcgttgaa tttgcggccc ttgtagatga attctcctgc
      721 gaagtagtaa tttatgttag gatgagtttc aagagggggt gtcgggatgg ggatggggac
      781 gggggaacgt accgcatttc gtgcatttca tggagaaggg ggccatgagg cggacggtta
      841 ttactttggg accttgtctg tgaagctttc ggttagaggg tattgtgata tttgtatccc
      901 agggtagggg gtactcactg gcgcaggtgc tttggtgtgc gcgtgatagc gctgggatcg
      961 aaatccgggg ggtagtattt cctttacata tgaggttatg ttagttgctg tggttgtctt
     1021 tcagatgttg tgggtgtgac ttacgtgagg acctttcgct cggacatggt ggcggattat
     1081 ctgtaacgtt cgtatacaag gtgttgtgta tgtatgggtg gaaaggtgtt gacgataagt
     1141 tgaaaagtgt aggaggtgag tgtagatggc gattgcgatg cgatgctatc ggatgcactc
     1201 acgtgacgtt tacttcttat ctatgcacac aagataattg atgaatgctt actaattatg
     1261 catttggctc taactaaatg atatacgcct ccaatgctat aaccgaacca tggtgccagc
     1321 tccaatgaca aaaccagggt atacctctcc aaacgcccag tcgctatgct ccaatgtttc
     1381 ctgtgtcctt caactatgtc tagcgttgct tcgcatccgc gaccctcggc tgcgccctcc
     1441 cgccgggcct ggcgtgtcgt tcatttccat gtcccgactt aggcctggct gtcgcttgct
     1501 tcgtccgccg cgtacacggc tcatagcatg tcggaggagt ccatcagcct catcatcaag
     1561 ctccatctcc accttgtctc cagctgtctc ctctgtgacc gtggtttggc tgtcgacgtg
     1621 agcaacctca tcggtccact cctcggcgta tgcttcgtcc acagtcccac gtcgtcgaga
     1681 tactttcccc tttcccttgg aagaccgtgt cgagctgcgg cttgtggtga tccgtgcatc
     1741 ctctaacacc accggctcct cctggccttc taatgcccag atttccagtg ctcgcgataa
     1801 gagcgtgcca gcaatgccgg caccaccagc tgcatcacca ccaccactcg ctcccaagac
     1861 acgtactgcc tcatgcaggg ctgtaacggc ttccatggtg cggttcagct ccaacagcac
     1921 caggccgcga gcagtgtgca gggatccaat caaccctcga tcctcgtacc ctccaactcc
     1981 ggatgaggcg actccagagg catttcctcc gctgcctcct aggaacgggc tgtacccgaa
     2041 gcttgcaccc gccgcaccaa tgcgaagaca ctcgtcgaac tcggccagtg actcttggaa
     2101 ttgaccgata cgtcgcaggg catgcccgag attagctcgc gtggcaaccc aggccccagg
     2161 ttcacattga agggatgtgg ccagcgtgag ggactgacgg aacagctcga cggcgccctc
     2221 gaggtgattc tgatggtaca aaactacacc cagctcgttg agtacgagcg ggtcaccacc
     2281 caaagaggtg agttccgacg gattggccct tatagaggga gcagagctag acgcggatcc
     2341 ggtcgacatg gaataggcgg ccgacaggta ctcatgggcc aaggacatgt tgtttagcgc
     2401 aagatgttgc attcccagga agagctgcgg taaatgactg ccctggaaaa gccgagctgc
     2461 agtgctatac gccgcaatgg cttgatcgtg ctctccttcg gcagcaaagg tatgagcgaa
     2521 gccaatccat gctggcgcag aatgcgggtc caaaagagac gctttggaga aatagcgtcg
     2581 agcttcagcg atcttagaga cggacaagta ataaacacca attgcgagat atgtataaga
     2641 ctcttcggga gcatgatcgg caagcgtatg ggacagaagg aacagggcgt tcgtggcacc
     2701 cgtctcatat aagcaagcca aatgcaaggg gtacacggca ggcggatgtc ccaggtggct
     2761 ttgggcggaa atatggactg caggcgtcat ctgcgacgaa accgcagact gagatgtgga
     2821 cagaactgac gaagtcagtt ccaaagcttc agcaaatcgg cattgcgtat atagagcttc
     2881 agcgcgagaa agcagaatat ccggattctc cgctaggttg tagtgagttg atagggtttc
     2941 ggtagcgtct gagaggatcg taggcgatga atatttcgac aatcgggtgg tgtaaagcat
     3001 cttcgtaaag tgggcggcct cctgcgcgac tgactggtcg ggactcgaca cagagtcgaa
     3061 atcaagggac tcgaggaatt ccagctcctc tgccggagac atgagggagt tcttcataag
     3121 ctggtcaaaa gcctcgaagc actgcacgtc aatgcgtacg gcgtccttgt agcagtcgcg
     3181 agcacggtca aacgcatttt gtttcgcaaa gcagagtccc cgtaagtaac acatcgccgc
     3241 ctcaaaccga acgttatttg catcctcccg ctctcgctct tcgccccgat cgatgcgcga
     3301 cgctgtcgtc tttccgttcc gcaaggtaac atggctttga ccgttaaggt gttggatttt
     3361 gcggcgacta ttgctgctgc gtataagatg cgtaggatta tgatcgccca ggactgaaag
     3421 tgcctgatcg aactgattct gtttgatgtg gcagtgtgcg gccagatagc gacaagccgt
     3481 acttctggag atcaggtctt ttcgtgacag gagggccaag gcacgggcgt agttgttgtt
     3541 cgaaaaatgt acttgtgcga gccaaaaggc atcagagtcg ctgtctagag aagcaatagg
     3601 ttcagcactg atcgggatga tactgggttg gctcactcac tggttagcgc aagcacttta
     3661 tcgccaatgt agatggccgc atcatgctgg ccccggttca gcgcatcctg acgccaggag
     3721 cgcagaaact tctccatgac caaataaagc acgtgggaca cgagattgag tgcggttcaa
     3781 gagcgagggg ctgtcacaac ggtcgcatgg acagaaaggc atgaggcggg ttggaggggc
     3841 gacggcgtcc ggggagagta aacagaccgc ggcgtccctc agcaggcaat acaactttcg
     3901 cagagaggag ctggctatca cactagcagt gctaggttga aataccgtgt acaggcctgc
     3961 aaacagagag aaataaccgg aaaggcaata agcaatgtgg tattggagaa tgaagctccg
     4021 tcggattgtt gcgagaatcc aaagtccaaa gcggcgcgtg ttcgggttcg ggtccgtgcg
     4081 tcttgcccga tcgagaagcc gggcggatgc tgcttcatct tccactgctg tatatcgatc
     4141 tagtctattc agtctatctt caagctctat ctatctaccc ttaacgagta gcatgctctc
     4201 aataattctc aaaatacctt tgtaacccgc caaccaacac tggctccctt ggccagaaac
     4261 agaaatagac aggctccagc atatgccgct ccactgaacc caatcaagcc ggaatactct
     4321 gtctctactt tcccccgatt ctgccccttc aagatctcac cagccacagg aatggcaact
     4381 aacaacgcaa acgccatcag cgcgattgtt gtaccgaatc gtttgccata gctctcagtt
     4441 ttggagattt gagccacgca gacgggtgtc agacttatcg ctggtccgct ccaaaacccg
     4501 actaatgccg cgaaagccag gatacaagct ttgtcggtgc ccgccgtaaa ccatagacca
     4561 aaggacagaa tagtacatac agcacaggtc ccaaacataa cgttgaagcg gccccatata
     4621 tccgctaaga ctcccggaat gacgcggccg aagatagatg ttgcgctcat gatcgtcatg
     4681 agctggtagg aaagggcgcc agtgatgccg tgcgattgtg cataggacgg ataataggtg
     4741 actaggacta tcaagccgat ttccgcgaaa atgacggcga tggaagtcat ggtgaagacg
     4801 ggctccttga gcgcgcgaat gtcgatcttg ttccctgctg acggactagg tgggagacgt
     4861 gcttcgagag taagcaggct gaccattagg ctagcgagga atataaatcc caggatgcga
     4921 atagtccagg gaaacccaat tttattgctc aggataccga acacattggt gaagataatt
     4981 cctccaatgc caccccctgt cgtcgcgatc ccggtcgcta gaccacgtct tttgaggaac
     5041 cagtgcgtga tgcacgcagc actgggtgtg tacactgctg atgcagagag cccacctaaa
     5101 atgctgaatc ccaagatgaa ctggtagtat tcttgaccag gcaaaagtca gtccatgaaa
     5161 ccggggctgg agatatccaa ccgtaccgtg ggagacgctg aggaacatca tcgacaaggt
     5221 catgccaatg cagccaggca cgagaatata tctgacacca tgtgcgtcaa atatgggccc
     5281 tccaggatgt gtcagtagat gttcgagcgt cggaatggaa gcgatgcata ccaatttgga
     5341 tgccaccgag atagaagaag aaaagccaca aactgaagat ccacgagatt gatgcttttg
     5401 aatattcatg tagctggtgt tctgccagcc aatcttccaa caacccgtac aggttcatta
     5461 ttcccattgt cgggaagatg gcgcaccatg cgcccaagac tactaaccag gctcgccatc
     5521 ctccttccgg gaaagatgac gattcttcgc tgtcaacgag tgtctgggaa tcatcgtttt
     5581 tctcgttctc actcgaggct gcttgtatca cggtgcagac atcatcctta gttgactcca
     5641 taatgatgta tgaaggaaca agagtgaatg acccagaaag ctggaattgc tggaacataa
     5701 ccagcagcag cagcagcagc atcagtcgcc atgctgttac gaacacagca taccactagt
     5761 ttcggcgatc attggagcaa tagcctatct ccttcccgac ggagaattcc cttgcatcgg
     5821 tgactgtgtt cccgagagat agcatgttgg cgagattact attagcaaca ggagagtgaa
     5881 acaagtatgc aagacatgcc tgtatcagca tcgatctaca ggatctacag tgcagtggcg
     5941 atagcgctgt agggacacga tatgaaaaag caaatcgcca tttgtacaac ctgctgagtc
     6001 ctaaagcgta tcctactaac actacttgct cagtgacagc tatcggcatg ttaaaatctg
     6061 gcccaaggaa cttattgatc aggtagaagc gctccgacca tgtgcatcga acctaccaat
     6121 aaaacccaga tataaaaacc cgcattctct gaattgactt cttaacagta tgaggcattc
     6181 caaaccatcg caaaaaaata taaatagagc agtaaaccca aaattcacgt aagcatcgtg
     6241 atgatctact actagtattc tcaacctacc gttatgacta gtatatgcta aaagccatcc
     6301 tgaacagtaa gttatgtatc ttagtgctcc cccgccaacc tagcaatgca aaactattat
     6361 ggacttgtta ctaagaacta aggattttgt cttcccatcc tggatcgtct aatgatatct
     6421 gcaacaattg gttttcctgt gttcttaata attaagccaa gtggatgttc gatgcatctc
     6481 gttagcctct agtcaggata gcttcttctc atactcatca ctacaagtgc acaagggggt
     6541 tgatcaaaac aaacaaaata tagagactgt gtgaatatag tagtaaattt atagtaacta
     6601 gtaattcgaa ggatccagca cgcagcattc aaactgtatc ctggaaagac gtaatcgcgg
     6661 cccacatcaa acaatataac tcttcaatct aagtaacctc tgcttgccca tttccaggac
     6721 ctcgtcttct ttgcaaaacg caaatcgaag aaaatcctca cctatatgcg cattgtcatc
     6781 actatagaac tccgacggcg gaatagcggc aacgccaatc tcctggatca agaaccagca
     6841 aagcttgaag tctcttcttc gttgttcgat atgtgctggg aatacataat cgctggggat
     6901 ttgtacccgg gataagttca ccaggacaaa gtatccgcct tcgggttcgg tgtacttaga
     6961 aactctcgtc agtacgaatg attctctttc ttccaaaggt tccataaatg aatcggataa
     7021 gaaggacaaa ccggtagtcc aaggtcttcg aaaacctcac agaacagcct catcttatct
     7081 ttcatttcct gccggctatg ctcccaaaag ccgtttctgt ccgccgcttc gaaagcaacc
     7141 gccactgctt cctgtagcgg agatacgctg ctgtagcaga tgcgggtgtg tactgcggaa
     7201 acatatttga tgagttgctg tggcccaatc agatagccga ttctccagcc cgtggcatgg
     7261 aaggctttcc cagcggatgc gacagttagt gtgtggtcgt agaggtcagg ggagatagtt
     7321 gcgattcgcg taaaggggac atagtaaagg tggtcgtaga cctcgtcgga gaggatcaga
     7381 agatcgtgtt tcaagcagaa gtcgccaatg cgctggagct ccgtctctgt gaagactttt
     7441 cctacggggt tgtgactgca gcgcggtggt tagcttgttg gattagtgag gtgtaaatga
     7501 attgaggcgt tcatacggcg tgttgagtat ctggacttgg ttagtgaacg cataataagg
     7561 tagtacagag gataggcaaa ggatatggcc catacaatca tcttcgtgtt tttgtttatg
     7621 gctttctcaa gctcttcaaa gtcgactgtc cattcggatg cacttgctat tgccctactg
     7681 ctgttctttg gcgggtgaag aggcacatag cgaggaatac cacctgccag ttcaattccg
     7741 cttctatatc tatcacacga tggctgggag tcaaacctgc ggaaacaatg tcttgtccat
     7801 gaaaacatac tggtcaaaga agggttcaaa tgtgacgact tcgtcaccgg gatgtataaa
     7861 tgccagtaat gcacacagca tgcctgtata ttttttactg atcagtgacc acctgaacgt
     7921 gatagttacc tacaggctta ccttcattgg cacctgaggt gatggtgact tcattctcct
     7981 cgtcaatagg tctttcaagt aacttggaat aagccgaagc aatggccttt ctcagactta
     8041 ggcggcccta ttgaactctc agtattaatc agatctatac aatgaggctg tagctatagc
     8101 tttaccttcg ttggagcgca ctggttgcaa tcaaccctat tgagcgcttc cttggccgca
     8161 tctatagcaa actgaggcgg gttaaagcca cttaatgagt gattaggtat ataatcagcc
     8221 acacggacag aaggaataag ctcacaagaa gccttgtccc aggttcacga ttggttgaat
     8281 tggagatata gcagctgctt cgttgacgat tgacctgtat gtgcttggtt agtgttctat
     8341 atatcaaagg tgtcgatgag tgtgaggaga taatggatgt accagacatc cagcctgtca
     8401 gaggccaccc ttggcgccgg agtactaaaa gaaccgctgc tgctacgtgc ctccatgttc
     8461 agacaaggac tggagctttt ggattctggg gatgagaatg gtttctaggc ggaagaccag
     8521 tgtcctgagt gccgtgagtc ttttgaaaag gtagtctgag cgtcgaagat actgggaaac
     8581 ctgttaaacc caagaaagag agtgtattta atcaaagaaa agagaattaa tgcctataca
     8641 tgcaggggtt cgacacctca agatagtcca tcttctaatg gccacggaaa ctacatcccg
     8701 ccaaacagaa atcaagtgtt gtggtgcatt gttactaatg cgtgccaaag agcagcaagg
     8761 gcttacgtta ccaagccaaa atcaaggtcg gaaacatcac aaggtcaata tagtagtgtg
     8821 atgagctcag tcaaccttga tttcttcagc gcaggagtcc ataaagcaca atcctgactc
     8881 gcggaaacat aagccgatgt gcctcactgc gtcgggcttg ccctacggag aacgcaacac
     8941 ctgcagcatt ggtactctgt gacctgtgct atactggagt tatatgtaac gtattactcg
     9001 cgggctgtat gtaagatcac ttatgtctag atcgaacagt cttactcgaa cagatgcgag
     9061 ttgggataat gagggaaggt gacaccagta ctcagtcaca gaacagggta ggagttataa
     9121 cataagcttg atttgccacc aacctgcttg aacagaacaa aggtctcaca agccaatcac
     9181 ttcatgattc tgtttataga gattccctgt aatctcactc tacatagttc tcggatcgga
     9241 ctccatgttc tgtccgatgt tgcaatttgt ctcatctgca gtcttgcata actatgccta
     9301 aagcttccgg gaaccctgtt cctgcgggaa atcccaggat ggagatgcat ctgcaccgtt
     9361 tggtcgagtt gcacgagcaa agccgttctc gactccctcg atctcagcta caggtcgtac
     9421 aacttccacg tccgctccgt agtgatgaga gtaccatatc tctgtcagac tattctggcg
     9481 atcccctggg gatggttcca caaagaggtg tggaaaccgt tccctcatga cctctaatgc
     9541 caggacagaa ctgcggccaa cgctgtcgca gaagcgtaac ttggaaaatg caggagcaaa
     9601 ggcatgctgc agctgtgact ctgtagagtt cggatattgg ccgacagcaa agagcagtaa
     9661 gttgaactgc atcaaggaaa cctgaccaat atacgatccg ccgtatcgta tacgattgta
     9721 aaggcccgtc aaggcagcga tggcacccat gcaaccggcg ccagagtcag ctataggcaa
     9781 cggggatacc atcggttccg ccgcacggcc aaggaatcgc ccatgacacc ttgcaaatcc
     9841 ggtgagctat ttgcaagtca gttttaatag gagagtgtcc ctgcaaagct catttgggtg
     9901 tgttacatac gcaatcggct atctgttgcc atcctgggcg atggcaccac tcaccttcgt
     9961 gcccaaagca ggtttcgtct atgtagacga tccctttccc acgcttctct gccatggcag
    10021 ccacagtttc tgggctgtat ccaagttttc gaagggcgcc agggcggtac ccatcaatga
    10081 tcacatcgac atcagcgaga agggcttcga aatggcggcg atcctcatca gccttgagat
    10141 ctaattccac agcacgcttg cccatgttat tgtcgacctg aaagaatggt acgtcaggca
    10201 ccgttggaga tgtaaccttc aaaacatccg ctccgtattc agctaatgta cgaccgatca
    10261 tgggccctgc aatgacacaa cagagctcca agaccttgac accttcgagt atcctatgac
    10321 ttccactagg gttgaaagcg gctggcggtg tcttccctgg caggcgcata accttccacc
    10381 aaggttcctc tatattcgtt ctaccctgtt cacaatatga gtatatcttg gttttctgtc
    10441 cgtgtgagct gcgagggtca ccttacatgg ggagtgtttt tgaattcttc atactcgtac
    10501 accgtcaccc ctgcttgccg attcgtctcg ttgagtctct ctagctcagc tgctgagaac
    10561 ttttgaacct ggctctgaat agtgtttatg atctcatcgt agtcagtgag atccgcgcgg
    10621 tggctgtcta aaccgagcat tttcagagtg gaagttgggt tcaaagagcc atgcagatga
    10681 aagaactcgt tatcatgctt ggtccggtac atactggctg ccattcgccg atacggattt
    10741 gattgtgcag catggatatc ggtatcttcg tctcgtcaat tcctgctccc tgcactagga
    10801 aaaagagagc ggcttacctt tcatgtatcg tttgacctta gggtcggatc gggagtaccc
    10861 attgatcttg gcggccagtg cctgaaagcc gaaaagcgtt gccctttcca ggttgattgt
    10921 agtcttccgt tcatgtggct tagatgctga ctgcagatcc gctattagag ctgccagggc
    10981 tccttctatt cccttgagag ctgccagggt ttcggtgacc ttgaaaggga tcggatagta
    11041 aatcgtatct gaattggcct gaaactgtac tcggctacta tagatctcgc ttgggagacc
    11101 gagacgttca gagttctggc aaagaagatc gtaaattctt cttgcctctt ctgagggtcg
    11161 atacatgtcg ctggtcacct gtggaataaa cggggcagtt cgatagagct actagaatca
    11221 atgtcttctt ttttggttga ccggtgccgg caatatgtct gcacataaat gcatcaaggc
    11281 ttcataaata gcttcaaaat ataatgtctc atgcttagcc cagattaccg gtatctgagg
    11341 catgtgggat gggtatcccc ttgcatcaat agtcatctca tcgtctcctg tctcgaagca
    11401 gactccgacc atcaccgagt gaccgtatcg aaaacatgca attatgacat agtattgtac
    11461 ttatcaagaa gggaatacca gtgctttcta tagcgtcaat ggatgcatta acgatcgtcc
    11521 ctcgctgatg caatctgttg tcccaccccc gaattgggaa caagtacagt gtaatatgtg
    11581 tataaaccga ataggagacg aggaaaacgc acctgttcgt gatacattct tcgtagcagc
    11641 atttggtaac cctgaagtag tacggagaat gcaacctcgt ccggtggatc tgtgacgcta
    11701 cttaccgttc ttacagaaat tggtcagatg atgtgcgtaa tcatcttccc gaggagtgtc
    11761 cttaatggtc tactttggct acacaaaagt caagcaacat ggaacgtcgc gtacttgcca
    11821 ggataatcct gcaatgcgtg ggtttgctct tctatccaga ccgcgttccg gttccagcca
    11881 tgccattttg catgcggttc atctgcaagc aagataaagt tagaaaatgc tgttccttga
    11941 gcaattcata cattcgaaga actataaaat ggcagatatc ggtgcatact tttccgcttt
    12001 gcggatagta ccatcaaaca ctccatttct gcttatatct ggtccaagcc ttggccttat
    12061 ctcccctgat ccagtcgagc ctccacttgt caattcactg gcacaatgac cgtgaattct
    12121 ataacagaca tcctccgcaa agcagcagac catcaggaac ctcgtggtgt ctgtgcctat
    12181 tcgaccggca tcgctgggat cggttccgca acgaggttaa gttacacaga gctcgattca
    12241 ttggccacat cgaatgctat actactaggg cggctgcagt gcgacaccga gtctcctgtc
    12301 atactacttc actttgaaga ccatctggac aatatcatat ggttttggtc taccttatat
    12361 gcaggctaca ttcctgcaat gtccactgct ctgcctcgaa gtgaagaaca ccgcacaagg
    12421 catctctgcc atctaagcga gctgttcgat aagcctatct gtctaactcg gaaaaccctc
    12481 caaaacctgc ttacaagaga gtctcccttg cacgttgtgg ctatagaatc attgaatggt
    12541 tcatcagcag agtttgtcgc tacgacagaa gccatttcca gagcaccagt aaatagcggt
    12601 ggtgggcatc ctgctctgct gatgctcaca tctggaagta ctggtctgcc aaaaaccgtg
    12661 tctctaacac acaaccagat actggcctcc ctccaaggga aaagccattc gctatgtgtt
    12721 gaggacactg gtgattcgtt cttgaattgg attcggctcg accacgtcgg gagtttcatc
    12781 gaaatccatc tccatgcact atttgtcggg tacgaccaag ttcacgttcc gcctaacgag
    12841 ataatatctc gtccggcctt gttcctcgac ctcataagtc gacatcgtgt agttaggacg
    12901 ttcgcgccca actttttcct cgctgaagtt ggccgttatt tggagacctc ccaaggagaa
    12961 gatagacctc actttgactt gagatgtcta cgatacatcg tatctggtgg ggaggctgtt
    13021 gttgccagta cttgtgccaa agtttctcga ttgctggtcc aacacggcgc acctgaaaat
    13081 gtcatcgttc ctggattcgg catgactgag acttgcgcag ggtgcatcta caacttggaa
    13141 tttcctgcgt ttgatactcg caacgaaaat gagtttgctt ccctgggaaa gtgtgtcccg
    13201 ggcgttcagg cacggatcgt ctccatagct acgggtgaca gtcccgcggc cttaggagag
    13261 gaaggccagc tggaactcag aggtccgctt gtattttctg gttattacaa caatcaagca
    13321 gcaaccagtg aggctatcgg ccccgatggt tggtttcgaa ctggggatac gggttacatc
    13381 ggcgcgggcg gcaggataaa tctgtcgggt aggactaaag aattgatcgc cgtcaacggt
    13441 gtcaaatatg ttccgcatca gctggaagcc gctatagagg aagcaagcat accaggtatt
    13501 gtttctggct gtgtgatatg cttctcattc cgtcccaagg gtgcagagac agagcgacct
    13561 tgcgtcatct accagcatac ctattgcgtt aacgatgcta aagctagata tcagacgatg
    13621 actgccatct cgcaccgtat cacgatgata acaaatatgc gcccgtatat attgccttta
    13681 cagactgtaa aacgcacatc cttagggaag cttcctcgct ctagcctgca gcgggaggtt
    13741 gcaagtggtc agtacaaaat gaaagaagct atcgacagag aaatgatcaa gaagtatcga
    13801 caagccattt tcaggccacc cgagtcacct accgaaaaag tgatcgtgga agagctgtca
    13861 gaactcctgt ccctacctca agaagacatc ggaatcgaca ccgacctctt cgaactaggc
    13921 cttacctcat taacgcttat ccggctccaa caggccttgc gaacaaggct gtcactaaat
    13981 gagccaatcc ctctcgccac gatgattgcc cataacactg tccgtggttt atttgaagca
    14041 tgccaacaac atcaccaata catcccagcc gtgaagctcc aatccagcgg caacaagaca
    14101 cctctatggc tcgtacaccc tgccgcaggc gaagccctca tattcatcaa catagccaag
    14161 ctcatcacag accgacccgt ctacgcattc cgggcccgcg gattccacca caatgagcca
    14221 tatttcacca gcattgacga atgcatccgc acttaccact cctccatgaa gaagcttcaa
    14281 ccgcacggcc cttacgctat cctcggatac tcctacggca cgatgctagc atttgaactt
    14341 gccaagtccc tcgagaaagc aggtgaccaa gtccaatacc ttgccggcct taaccgtcct
    14401 ccatatgtta gtccagtcct gaagagagtt acatggaccg actgcctagt taacatctcc
    14461 tacttcctcg gccttctttc tcgagactca taccggactc tcctccggga gatctctgtg
    14521 tttccgaagc atgatgcctt ggccagagtg atcgagaaag tggatcctgg ccaactcctg
    14581 gcgttgggcc tcgatgaagg tagcctagaa cagtggatca atgttgcctt cagcctacag
    14641 gagataggaa gagaatatga gccgcgtgga gtggtaaatg cacatatgga tgtctttcat
    14701 tgcactccat tggagttcct gaatgttaca cctgaagaat ggaagcgacg tctggctgct
    14761 tgggagaatt tctccagaca gaaggtgaac ctgagacatg taccaggtga ccatgctaat
    14821 gtcttgggac cggatcatgt gcaggtgttt gtgaagaagt tgggtgaggc tatggcgttg
    14881 cagggtcttt agtatccagt ctctatgtct tcgcctggag tagtgtaggg gtaggatatg
    14941 atttcagtta ccatggaata tacttactgt tcttttacct ggtaatttat gaagaccaat
    15001 ggctcttctg attttggtga aggagcggga aaagtccggt taactgcatt cgcaatgtca
    15061 tcccttccct tgaagatcat accaattcta ccactgatat ttttcgtatt tgactgcctg
    15121 tataaacctc ttcaaataaa attcaagtac gtatgaccac aaggtgtgga aaataggact
    15181 tcctgttacg cgctcagcca tactcaagcc acagtaatcc acgcgatcaa tcctcaatgg
    15241 gcccttgatc ccactaaaga tctgaaaaga ctgcggaatg tctcttgggc ggttgaggtt
    15301 actttactat ttattggaaa aggagttatt catgactaca tatcccagcg aaccagagtc
    15361 caaacagagt cctaactttc tccgttcgct ggttccgggt ctcgagccgg tgctatcgtg
    15421 gaatcaagtg ctttcacagg caaccaacaa atgtctgtat tacaaagtag gaagcctctc
    15481 ctctatcctt gatatagggg tttgaacctg ggaggaaaaa tgatcagacc taacacctca
    15541 gcacctagct tttaaaatct agtggaattg gagatgaaag aggccttatc agaagctggc
    15601 tgataattga tttatattca ctaataacat cagcctatca tctgaaaatt tcagtgctat
    15661 tacaaaatgg gttattgggt ggtattcagg gaggaggagg aggaggagga ggagggagac
    15721 agtgcagctg taatgattga tactggccat cccgcaacat tcccccattt ctctacctcc
    15781 tcgactaatt ccacacgcct tggtgtgctt tgaagccagg ttccacctac agagacatat
    15841 caggacctac tccagagtaa gggagcttgt gtgcttaatg agacttacaa aaggcgaccg
    15901 gcccaaaagc attgacccat acagacgcac tctcacttga aatggccaac gcgcagattt
    15961 cagtcgcatg atagtcaagt ctttgacgca agcaatccat atcatctatg cgctgtaaag
    16021 ctttcaaggg ccacgctgcc ggctgggcca gccaaagaat acccatagcg gtatggtagt
    16081 aatggagtgt agatactggg tacgtcagaa gcaaaacgtt aaacgggttg atgtgacaag
    16141 aaatattacc gtgccagctt ctcagtgtcc atatggatgg aaagttgctc cgtgttttta
    16201 gccctggcgt ttgtattgta tcaaatgatg ggggtagagc ggatctccac tggtcgatat
    16261 cggccttcag ggctttccac tcgataatgt ctaaaggcgg agaatccaca gctaaacacc
    16321 ggtttataac ccgtcccagg agaaaagtga tataattcgc aaagtccata tcatcggtag
    16381 gttgtggagg agcatcttgg tccgatagag tgatcatgag tcctcgatgc tcaatgaggg
    16441 ctactgtgat gtcttcgcgg agatagttcc agtagccagc actgagtaag tctgcggtga
    16501 ggtgaacatg ccgagtagcc aaaagagaat aacatccttg cagatgactc tgtgagctga
    16561 cattttctaa tcatagatag ccatcatgcc gttagcttta gccgcgacag atgaaaagat
    16621 gaggtgggga accctaggtc gtaggatcta ctaacgtgtt attatttcgt aagagcgaag
    16681 aagacaaaca gcagccaagg tctctccaaa ggggagctga tcgatgttct tggtgagaga
    16741 tatcaaactc cgaacactgt catagtgata agcttctgcg agttttagat agatatggtc
    16801 tccccgagtg cggtgcagat tagcagcgga aaaggcgagg atagcactga gtaatagcgg
    16861 attacgtcgc gctcggatcg gaacgatgtc cttgaaatga cgcctactat cgttcaggtc
    16921 ataccacgca gcaaggttct ccatatagtg acaaaatatc ttcgcaacct gtggatcttg
    16981 cagggcatgc tcgggggctt gagccgacgg gtattcagct tcagggtcta ccgttgcact
    17041 taacgagctc ccagaacggg ctgatgaaga agcggtgcct tgcgaagcgg cagtaccgat
    17101 ttgctggatc cagtaacagt ggcgggaact tcgctgacaa ggcgaacagc tgggtcgttt
    17161 cccatcacct gtgcgttcgg tggatcagca cccgccggtc gaaagcgtca tatggagtca
    17221 atactaacat ttaattctcc gtgacctgca aacttggctt caagactgcc agttagcagt
    17281 ggttacctac ccaaccagtt atgggatcaa attgcaagga gacttattgt attcgatcga
    17341 gtgttcctta ccagccttat gttacatcag gacaggggtt ccattaaggg acggaacagg
    17401 tcacttacgg tttcgttcaa ttggtcgggg catttacgcg ttcggcgact agggcgcctt
    17461 aaatgaattt agtactaatt tgaaaggcga gcgatttaac gctgtttggc gagggcaaac
    17521 actgactgtc cgagaattta gcgagggcaa aagcgaaatg aatgatggtt ctgatttttg
    17581 agattgcttt ggttcgggaa tgtcacctga tcctcatgac ataatgtctt taacgaaaga
    17641 tgaaaatgcc aatgaaaaag cggcatgagc gagggatgaa agacgaaaag cgagatcgta
    17701 caatttcttc ttggcggaca ccagtggagg taattctaga aatcttgggg tatcttgttt
    17761 tcccggtgtt tcggtgaccc gacccactta cctcggtcct gaaggattga tagttgttgt
    17821 ccggtaaata gtggaagata ttgtacttgc ttgcatccat ctgctgtgtg gacaaccagt
    17881 tagacactcc tccccgagta ggaatagtct gcatcatgag atgattcgaa gtagatacgg
    17941 tttagttccg tagcttagct tcaacgttca ctcgtacggc ggtccatgga gaccaggcac
    18001 aggaccaatt ggcggactaa tattcatcca attttcttga attgcggggt tgttcccatg
    18061 tctctcgcct ttcgctcttc gtctttcgct ttaccccaac caaaagaagt aagagcttgg
    18121 gtgatcattc ccggcgatgt aatgtagagt aaaagaaaca taatggatga tttccctccc
    18181 gccagaccaa ttcaataaat agctaatata tacgccaatt caggagttat accggcaagt
    18241 ttttcttagt ttgtcttcct gtccattgtt tcatacccaa aattctcgca acatggaatt
    18301 cgacccaagc attcgtttgt ttcccccgtt ctcctacgat gggtctcaga gttaaccatg
    18361 ttattacacc agcgggatat tccacctccg acgagtctag ctttgctttc atttctgccc
    18421 atgagaggtg gccgatcatc ttggtgagtt actcagtctc acagaacccg gctgaatgta
    18481 gcctaatcca tggctttcgg cataggacgg cataattgcc gatgtctctg aaacattgtc
    18541 cagcacgaag aattctgatg ctagagccga gggcctgaaa atcatccaag ggtttcaagc
    18601 gttaaaagct gaaattcagt cagatgcgaa acttttgtgc gtctatacaa tcttagcgct
    18661 ccattctact ggacactaac ccggaattaa gaccattaga aattgatggc tccactgaaa
    18721 ttgtcgacta caacaaagag ctcgcccaaa gaaagcctac ctggtttaat gtgttctggc
    18781 tgtatgggga gtgctattta tgtaggtttt acattacaat atactgttgc ttatatgctg
    18841 atctgaacac tttaacagac agaagaatcg attctctttt ctcgcaatcg ataaattgga
    18901 aaggttacga tgtcttcgca cggcaaaaga agtccacatt tcagtcctcg aaaaccgcaa
    18961 ttgttgagct cgccgcgagg tacaagacgg ttctgagcac tgccgctctt aaagacagca
    19021 cggtagaggc attccatttc aaggaaatgt gcgagatatg cctctggggt aacgccacag
    19081 atctatcact cctcacatcc ctgacatacg aggatattca aaagctacaa ggggctgaag
    19141 ccagaaagtc ccaagagaaa aatgtcctta tcaacgatat tcccgtcgtt tacgatgtta
    19201 tgaacaaggt ccgtcaagac aagggagctg gaggaagagt tgacattgta ctggataatt
    19261 ctggcttcga actatacgtg gatctcctcc tggccgcgtt tatgttgtca actggactcg
    19321 cgtccaaagt tttacttcat ccaaaatcgc tcccatggtt tgtgtctgac gtcgtgccag
    19381 ccgacttcac agacttgctc atggctgtgt ccgaaccgga aagcttcttc ggtggagata
    19441 tcaagaacaa agaacaagaa acgggaactg ttctaaaaga acatgagaag ggtggtctcg
    19501 actttttgtg cgcgcagtgg aatgcctttc gaaaatctgg gaagttgatc gtgcaagaaa
    19561 atccattttg gatcaccgca aatagctact ggcgattacc atacatcgcc cctggtctat
    19621 ttggtgagct ccgagaaagt gacttggtca ttttcaaagg tgacttgaac taccgaaaac
    19681 tcacgggtga tgtatggccc ttaccctatc actattcgaa aactaggatc ctcgttggct
    19741 gaagaggcta acctccgcgt ttttaggtca aatgggatcc cacaacatca ttttcagaag
    19801 ccatagggcc gctaggtcaa ggttcgggtg tacgcacctt ggctttaagg acttgtaagg
    19861 ccgatgttgt ggtcggcctc gctgagggtc aagatgaagg tcttcggaat gcgcatcata
    19921 gcgagtctgc ccccaaagaa cgtagatggg catggacagg gaaatgggcg gttgcctcct
    19981 tctacgatgg taaatccata gaaaattgat ccattttcca ttgcacgaga ctatgatggg
    20041 tttgtttgta gggaagacat ggtaaaatcc cttttctgat accaaatgcg cctccttggt
    20101 aaattgttct aactcagcga gaaaaaaaaa aaaaaaaaaa aaaaaaagaa aaaaaagaag
    20161 aagaagaaga aggaaattag tgacaatgcc gaacggctgc atgaaacttg aaaatattcg
    20221 atatcacaga ataattgatg cgccaagaaa cctattcctt atgacatata aatctcgaga
    20281 gacaaatgtc ctctcagtgc aatgagccta cgatttatgg gaattgtctt ggactctcat
    20341 agtcaaagga ctgtgtcaga taaagaggga gaagcgattc tttctgatcc agtgctctga
    20401 actgaaacag tggacctggg actcaagaaa gaaaaggaag gaaggggggc atagaaacta
    20461 agaacgaaaa acgaaggaaa aaggaagaga aagtgaagta acccgaaatg aatccaatct
    20521 tatccattgt gctagaattt atggaataca ggagctacac atggtcgaat cacatcaact
    20581 caaaaaaggc gaacagacaa tccatcaata gcttaaggct cctggctgaa gtcgtaagca
    20641 ttgccaaaac cacggttcaa atagcgcgac atggcctcag actttgacac ccagttgcat
    20701 gggacttcga cgtcagcctg acttccaatg agaggcttca agtcatcggc aaactcgagc
    20761 ttcatagggt tacgatacca cgaggcaaaa tggactattc gtgtgagatt acctatttcc
    20821 gacacgatca aaaaggatga cttactcatg gccagcatca cgcgaggagt ctcagtctgg
    20881 ttgccaattc cggcatgcca caggcgtagg tctctgataa caagagagcc cttagcaacg
    20941 gtaggctggc aagggggccg ctctatccga cgcttttcga gctcatcgag cttgattcga
    21001 ccacttgcgc gctcaccgtg gagcccctct tgaacatgga gtccagtgtc ggtgtgggtt
    21061 ccgagccaca cctcggtgga gccgttctcc ggggtcattg tgatgagagg cacattaatc
    21121 acatatgcga agggatggaa cggatgcgca aagtcggcgt cggagtgaac cggctgggac
    21181 atgggcgggt gctcagcggt gggtggcatg gcggtgttgc cagaacaaaa tgtccatttc
    21241 ggacggggcc ccaatgcgga tgaagtgatc tgcgtggcaa tggggtcttt ttgaaactgt
    21301 tagctattgt atagagaggg ggtaaaggtt tgtgatctcg ttggagctta cttagaaaga
    21361 tctgggggtc gaagtatccg cgcactggcg gggcatcctg ctggatattt ccggggttgt
    21421 agttgaacgg gctaccatcc tttttgtttc gaagtgtgta tgcatcctca gtcatctttg
    21481 cgttgagtcg atccaggcta tcatgaggaa tcacattctc caccacgacc agcccatcct
    21541 ggtgaaggct gcgcatggca acctccaaat tttggggcga aagtcgtgca ttttgaatct
    21601 cggtggtgga ggggcggatg gaggtgggat gactagcaag cttgcatagc tgagttgata
    21661 acgctcgggc ttgaaattgg tggctgaagc gcagcggcgc cttgagaaga atttgactca
    21721 t
//
