LOCUS       OGUI01000016.1         19661 bp    DNA     linear   PLN 19-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   OGUI01000016
VERSION     OGUI01000016.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 07:37:12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 663433
            Orig. end    :: 683094
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..19661
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[673326:673653](+),
                     [673699:674052](+), [674120:674448](+)}"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(9894..10220,10267..10619,10688..11015)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..19661
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..19661
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     mRNA            complement(1..963)
                     /locus_tag="ATCC64974_88880"
                     /product="hypothetical protein"
     gene            complement(1..963)
                     /locus_tag="ATCC64974_88880"
     CDS             complement(1..963)
                     /codon_start=1
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF01370"
                     /db_xref="PFAM:PF13460"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 94;
                     E-value: 1.9e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC64974_88880"
                     /note="EggNog:ENOG41; GO_function: GO:0050662 - coenzyme
                     binding [Evidence IEA]; GO_function: GO:0003824 - catalytic
                     activity [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_88880-T1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.1e-06, bitscore:
                     22.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MPLIFLTGGSGYLGHAITTHALSKNYTIHSLSRSPESDAKITSLG
                     AVPIRGDLTTHSVLREQSQKADIVIHLADPMAGNYSLPYEERIRIDDESVTAIAEGLVG
                     TNKPLVVTSGSLVVAATGTETDENSALWEEGKALNERIVSERKNLRWWEEKGVRVIVIR
                     LPPFVYGRGGSGVGLFMGMFWNGGDGGKKEVKVVKEAEEVVTSAVHVEDAAELYLLAAE
                     RAGAGEVFNGCSEWGVTFGELGRAMADVLGVEVGLVGFEEAKRVWGEFFAGFLSTENRA
                     SGGKAMRVLGWAPKKVGIVEEVRHGSYVEVAERLRNGAA"
     mRNA            complement(join(1401..1472,1531..1630,1688..2222,
                     2299..2341))
                     /locus_tag="ATCC64974_88890"
                     /product="hypothetical protein"
     gene            complement(1401..2341)
                     /locus_tag="ATCC64974_88890"
     CDS             complement(join(1401..1472,1531..1630,1688..2222,
                     2299..2341))
                     /codon_start=1
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF00106"
                     /db_xref="PFAM:PF08659"
                     /db_xref="PFAM:PF13561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     102.1; E-value: 5.7e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC64974_88890"
                     /note="GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_88890-T1"
                     /transl_table=1
                     /translation="MSSPTIYLITGASRGIGLALTQTLLLLPNTTVIATMRNPTTNSLY
                     TNPPPTSPTSTLILLPLDIQSTTSITTAIETLKSKHNITHIDTVISNAGYYNDATHRVD
                     NIPLSTVQSHLDVNTLGTIRLFQGVYDMLKKSTKPMFVSVSSFLGSIGGLEEEFFPGAA
                     YGVSKAASNWVTRKMHVENEEMVCFMVHPGFVKTEMGNACAKSIGLEEAFSEPKECAEA
                     LVKLIESATRETVGGRFISWRGEEVPF"
     mRNA            join(4572..5061,5111..5194,5245..6002)
                     /locus_tag="ATCC64974_88900"
                     /product="hypothetical protein"
     gene            4572..6002
                     /locus_tag="ATCC64974_88900"
     CDS             join(4572..5061,5111..5194,5245..6002)
                     /codon_start=1
                     /db_xref="InterPro:IPR012935"
                     /db_xref="InterPro:IPR013909"
                     /db_xref="PFAM:PF07967"
                     /db_xref="PFAM:PF08600"
                     /locus_tag="ATCC64974_88900"
                     /note="EggNog:ENOG41; GO_component: GO:0005634 - nucleus
                     [Evidence IEA]; GO_function: GO:0008270 - zinc ion binding
                     [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_88900-T1"
                     /transl_table=1
                     /translation="MSYAVETKKRKFHRVLESLTKPSTSDSTKSATAEAPTTARDASNK
                     KARLDAPNFSLARNSLLKVARPSSRDSSVSSTSRPSFVPWDRERFLERLETFRRVDRWA
                     PKPSAISEVEWAKRGWVCTDVARVTCAGNCGGSVVVKLPDELDELDGFDADKVQERKEV
                     RAKLVDEYVERLVKGHGETCPWRNKGCDATIHRLPLANPDIAISGLEKRYSNLIKMADQ
                     LPAADVIHTPESFDIEALIKILPASFNGPGESTRMESIENNTEGENGKENAHNSEPEPF
                     VPRNAFILAFFGWDSVPDGTAGLVGCSVCFRRLGLWMYKPKANGDEALYDSLEVVNEHM
                     DYCPWVNGKAQSGTGRATEKLEGLRSGWELLGQALNVRHRRLNRSTTSGDSRAVSEVPS
                     TDEPVVDDVNPEVKKASDREWWAKLRRMRQVLNVSSPRKKPTSQ"
     mRNA            complement(join(6207..6683,6740..7110,7168..7439,
                     7512..7813))
                     /locus_tag="ATCC64974_88910"
                     /product="hypothetical protein"
     gene            complement(6207..7813)
                     /locus_tag="ATCC64974_88910"
     CDS             complement(join(6207..6683,6740..7110,7168..7439,
                     7512..7813))
                     /codon_start=1
                     /db_xref="InterPro:IPR002938"
                     /db_xref="InterPro:IPR036188"
                     /db_xref="PFAM:PF01494"
                     /gene_functions="other (smcogs) SMCOG1087:hypothetical
                     protein (Score: 252.7; E-value: 1.1e-76)"
                     /gene_kind="other"
                     /locus_tag="ATCC64974_88910"
                     /note="GO_function: GO:0071949 - FAD binding [Evidence
                     IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_88910-T1"
                     /transl_table=1
                     /translation="MANTQQPQFRVLIVGGSVAGLTLAHCLERANIEYLILEKGDDIAP
                     QVGASIGIMPNGGRILEQLGLFGEIERVIEPLHQANISYPDGFCFSNVYPKVLGDRFGY
                     PVAFLDRQKFLQIAYEGLTKKHNVLTRKRVVEVRQLEHGITVAVADGTEYEVDLVVGAD
                     GVHSRVRSEIWKMAGENRPASVSRRERRSMTVEYVCVFGISSAIPGLEISEQINGIYDH
                     LSILTIHGRHGRVFWFVIQKLDRKYVYPDVPRFSDEDAVQLFERVKHVRFWKDICVGDL
                     WKNREVSSMTALEEGLFETWHHERMVLIGDSVHKMTPNFGQGANCAIEDAAALSSLLHD
                     LINARGVCKPSNSQVQHLLQQYQETRYSRMVGMCRTAASVSRIQARDGILNTVFGRYWA
                     PYAGNLPADLASKVMADAEVVSFLPLPGRSGPGWEMYRRKGKREQIQWVLIIFSLITLG
                     GLCIWLQSNASYVVE"
     mRNA            join(9894..10220,10267..10619,10688..11015)
                     /locus_tag="ATCC64974_88920"
                     /product="hypothetical protein"
     gene            9894..11015
                     /locus_tag="ATCC64974_88920"
     CDS             join(9894..10220,10267..10619,10688..11015)
                     /codon_start=1
                     /db_xref="InterPro:IPR000092"
                     /db_xref="InterPro:IPR008949"
                     /db_xref="PFAM:PF00348"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: fung_ggpps2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182:Polyprenyl synthetase (Score: 100.2; E-value:
                     1.8e-30)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ATCC64974_88920"
                     /note="GO_process: GO:0008299 - isoprenoid biosynthetic
                     process [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_88920-T1"
                     /sec_met_domain="fung_ggpps2 (E-value: 4.5e-116, bitscore:
                     382.1, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MAALPDVASIPLPLVATLGIAPLVFYLVLDRFGPLWPNSKTFLIG
                     KKKPETVTSFECPYAYIRQIYGKHHWNPFVQKLSPRLKDEDPAKYKMVLEIMDAIHLCL
                     MLVDDITDNSDYRKGKPAAHRIYGPSETANRAYYRVTQILNETVQRFPKLAKFLLQNLE
                     EILEGQDLSLIWRRDGLGSLSTVPEERVAAYRKMASLKTGALFRLLGQLVMEDQSMDGT
                     MTTLAWCSQLQNDCKNVYSSEYAKAKGALAEDLRNRELSYPIILALEAPEGHWVASALE
                     TSSPRNIRKALAVIQSERVRNACFRELKSASASVQDWLAIWGRNEKMNLKSQQT"
     mRNA            join(11768..12161,12463..12794,12858..13281,13334..13500,
                     13742..13825)
                     /locus_tag="ATCC64974_88930"
                     /product="hypothetical protein"
     gene            11768..13825
                     /locus_tag="ATCC64974_88930"
     CDS             join(11768..12161,12463..12794,12858..13281,13334..13500,
                     13742..13825)
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002403"
                     /db_xref="InterPro:IPR036396"
                     /db_xref="PFAM:PF00067"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 221.2; E-value: 4.1e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC64974_88930"
                     /note="EggNog:ENOG41; GO_function: GO:0020037 - heme
                     binding [Evidence IEA]; GO_function: GO:0016705 -
                     oxidoreductase activity, acting on paired donors, with
                     incorporation or reduction of molecular oxygen [Evidence
                     IEA]; GO_function: GO:0005506 - iron ion binding [Evidence
                     IEA]; GO_function: GO:0004497 - monooxygenase activity
                     [Evidence IEA]; GO_process: GO:0055114 -
                     oxidation-reduction process [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_88930-T1"
                     /sec_met_domain="p450 (E-value: 6.4e-54, bitscore: 179.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTPPLLPTSLISAILGITAHLTYFIHADLEKHVVFLVNCLIFWPS
                     LGLIALFILGYRDISQWIGPAILSFHFSLLASIAIYRYFFHALDGFPGPKLARITALWD
                     FKNTVLNAKWYIKVKEMHGVYGDVVRITLAGYEPYLLEHCKDIVRVIESRSSQAQEATA
                     LIDGFAWDSMGIFAFGKSFNMLHGEPPKMLQMMRMMGRGASALLSSSWLVILMRGMVGV
                     RRFTDRWLEWCAQCVEERSRVETNRRDLFSYLIEELSSEGDQSIGGVDGDLVRDSELAI
                     TAGSDTAASTLNALFYLLARHPDKLRRLQEEIDTAVPADEELSHAALVKKPYLEGCINE
                     SLRLCPAVLSGLQRETGPEGLRTAGVYIPPGMIVSVPTYTVQRDPRNFPRPNEFIPERW
                     STQPELVIHKEALNAFSSGTYSCAGKAFAMMEMRLLVSTIAASGQAGNTIKAGVSTKEL
                     NLSSTNSV"
     mRNA            join(13908..14069,14351..15891,15944..16110,16168..16202)
                     /gene="ABD1"
                     /locus_tag="ATCC64974_88940"
                     /product="mRNA cap guanine-N7 methyltransferase"
     gene            13908..16202
                     /gene="ABD1"
                     /locus_tag="ATCC64974_88940"
     CDS             join(13908..14069,14351..15891,15944..16110,16168..16202)
                     /codon_start=1
                     /db_xref="InterPro:IPR004971"
                     /db_xref="InterPro:IPR029063"
                     /db_xref="PFAM:PF03291"
                     /gene="ABD1"
                     /locus_tag="ATCC64974_88940"
                     /note="BUSCO:EOG09262QTY"
                     /product="mRNA cap guanine-N7 methyltransferase"
                     /protein_id="ncbi_ATCC64974_88940-T1"
                     /transl_table=1
                     /translation="MASKEEERTGQRPSISMYDPARDRWEEQPVVPAEPASASASIEAT
                     PTQTSEAKPVHDSTVTSTSESLHLPQTTTIEPSQQPEQQQKQPPIPTPPSSQSRRKHKI
                     NKMGDYYRSGSADAYAEQSSPAADSHKRKLEDETSEQQPPADQANDRPISKRKRLEERH
                     QKLRKRGQAPPSAYSRRDGDETAARAAPRPRSPSPPLPPRSPSPEVQARQRKRPGGGAR
                     RGLVDPQTLRRRQEERERALEEDAMRNSQSRGVTDIVRQHYNAVPQRGREWRKTESKIK
                     GLRSFNNWVKSTLIQKFSPDEEFVARAIGTKDWADGTGPPPMEEKRLLVIDLGCGKGGD
                     LGKWQLAPQPVDLYVGLDPAEVSIIQARERYAGMRSGRGPRGGRRGGPPLFHGEFRSKD
                     CFGEWLGDVDIVQQVGIDPNVGPGGSMMASRWGGGGFDVVTSMFAIHYAFESEEKARQM
                     LRNVAGCLKKGGRFIGVCPNSDIISARVAEFNAKRKDREAAKQDAEPEDGEVEEEAKAE
                     WGNSIYRVRFPGDTPEDGIFRPPFGWKYSYFMEEAVGEIPEYVVPWEAFRALTEEYNLE
                     LQYRKPFMEVWRDEKDDPELGPLSERMGVRDRTTGELTMTPEEQEAVSFYHAFCFYKV"
     mRNA            join(16609..17351,17426..18308)
                     /locus_tag="ATCC64974_88950"
                     /product="hypothetical protein"
     gene            16609..18308
                     /locus_tag="ATCC64974_88950"
     CDS             join(16609..17351,17426..18308)
                     /codon_start=1
                     /db_xref="InterPro:IPR004181"
                     /db_xref="InterPro:IPR013083"
                     /db_xref="PFAM:PF11789"
                     /locus_tag="ATCC64974_88950"
                     /note="EggNog:ENOG41; GO_function: GO:0008270 - zinc ion
                     binding [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_88950-T1"
                     /transl_table=1
                     /translation="MPKRSRPPPPTATPGPSGRNRNRDRDTTPPLPPYQPPTSTLTTLS
                     HQPTTAPALSALLATHTSSTLKTHLQHAQEKLTDAAGEINERLTDAKERSKKSRERRRN
                     IRSHTLENNNNNGEGVDEEGGDSEDEGIEEFEERVAQTTKVLEETIRGVIDAEVRGEEL
                     GRVISGLEGGVAERVRVRGVRRSQRGIGRRLRGHHGEDEEDEDGEEGVDVDVDEDEEGA
                     VPFLAQFEDELRGKMEEYEGLSLTRRYSTNNSYIGFYKIIHEAKHIGDEIPPPPHPSTW
                     FAHLEDPHSQSQPQSHPSASTSTSTTTTRQTRPTRARPQPPSEEEDEDDDDEIAIQTER
                     ISLKCPLTLLPFRDPVTSTKCPHSFEREAIFTMISGSNQMVPDPRGSSGTGRAKRVRSV
                     KCPVCEVQLTEFDLRSDPVLMRRVKRAEMAELRRREREMLDDGEDDQDGGDGGGGGGKR
                     KRSGRRRGSAVEVDDGDSDDDSGEDDGVERIRVKRERGMSVAARIKQERAVSMVGDGDG
                     DVEEVDMDEEGGGEEGGYDSMYDE"
     mRNA            complement(join(18655..18703,18763..19661))
                     /gene="MIC33"
                     /locus_tag="ATCC64974_88960"
                     /product="Putative mitochondrial 2-oxoglutarate/malate
                     carrier protein"
     gene            complement(18655..19661)
                     /gene="MIC33"
                     /locus_tag="ATCC64974_88960"
     CDS             complement(join(18655..18703,18763..19661))
                     /codon_start=1
                     /db_xref="InterPro:IPR002067"
                     /db_xref="InterPro:IPR018108"
                     /db_xref="InterPro:IPR023395"
                     /db_xref="PFAM:PF00153"
                     /gene="MIC33"
                     /locus_tag="ATCC64974_88960"
                     /note="GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]; GO_process: GO:0055085 -
                     transmembrane transport [Evidence IEA]"
                     /product="Putative mitochondrial 2-oxoglutarate/malate
                     carrier protein"
                     /protein_id="ncbi_ATCC64974_88960-T1"
                     /transl_table=1
                     /translation="MASPTAAKEPQPAVDFLHHPYTRAALPFVNGGLAGMTATVVIQPI
                     DMIKVRLQLAGEGVRTGPRPSAFGVARDIIASGKALDLYTGLSAGLLRQAVYTTARLGF
                     FDTFSKTLNKRAEAANRSVTFAERAGAGLAAGGIAAMIGNPADLALVRMQSDGLKPPEA
                     RANYRSVMDALFRISKHEGVPALWAGAFPTVIRAMALNVGQLTFFAESKAQLKKHTSLS
                     TQNQTFAASAIAGFFASFLSLPFDFVKTRLQKQQKDPKTGRLPYKGVLDCARKVVQEEG
                     WLRFYRGFGTYYVRIAPHAMVTLIVADYLNLITK"
ORIGIN
        1 tcacgcagca ccattcctca acctctccgc cacctcaaca tacgacccat gcctcacctc
       61 ctccacaatc ccaaccttct tcggcgccca ccccaacacc ctcatcgcct tccccccaga
      121 agccctattc tccgtactca aaaacccagc aaagaactcc ccccacaccc tcttcgcctc
      181 ctcaaaccca accaaaccaa cctcaacccc caaaacatcc gccatggccc tccccaactc
      241 cccaaacgtc actccccact ccgaacaccc attaaacacc tccccagcac cggccctctc
      301 cgcagcaagc aaatacaact cggccgcatc ctcgacatgc accgcagacg taaccacctc
      361 ctccgcctcc ttcacaacct tcacctcctt cttcccccca tcaccaccat tccaaaacat
      421 ccccatgaac aaccccaccc cactccctcc ccgtccgtat acaaacggcg gcaaccgaat
      481 cacaataacc cttacccctt tctcctccca ccacctcaga ttcttcctct cagagacaat
      541 ccgctcattc agcgccttcc cttcctccca tagtgcggag ttctcgtccg tctctgttcc
      601 cgtagcagca actaccaatg atccggaggt cacaacaagt ggcttgttag tacccactaa
      661 tccctcggcg atggcggtga ctgattcgtc gtcgatacgg atgcgttctt cgtatgggag
      721 gctgtagttc cctgccatgg ggtccgccag gtggatgact atatctgctt tttggctttg
      781 ctcacggagg acggagtgtg tggtgagatc accacggatc ggaacggcgc cgagggaggt
      841 gattttggcg tcgctttcgg gactgcgtga gagggagtgg atggtgtagt tcttggatag
      901 agcgtgggtt gtgatggcgt gtccgaggta gccgcttccg ccggttagga agatgagggg
      961 catattggaa gagtttcttc ttctgatcga tatttgattg gattagtatg gtgttttcga
     1021 ctgttgcttg ttggtttctg gtgtatggtg ggaggttata tatgtcgtac tctcttcgag
     1081 atagatcggt gttaaggggg ttaactccgg ggaggatccg gagtttagga tgagatgaat
     1141 gcacgatggg ggcgattggt tcaatagtag gggatatgag tgtgcccgcg gaatagaaag
     1201 ggcccgagga gtcgttatgc tgggatgagt gaataatacg cctatctcta gtgagcatta
     1261 tggttccagg gggaagatga tagggctttt tataggacag atagagaaca agctcatcag
     1321 gtcatgcgtt aaaggctcta gtatactctt ttaacaagcg caacatgcaa tctcctagca
     1381 gcctcctata tctctaccaa ttagaaagga acctcttccc ctctccaact gatgaaccgg
     1441 cctccaactg tttccctcgt ggcgctttca atctggtcta ctcagtatca caccaatata
     1501 taagaagtac aaatacgaat atagacttac caacttcacc aaagcctccg cacactcctt
     1561 cggctccgag aatgcctctt ccaacccaat actcttcgca cacgcattcc ccatctcagt
     1621 cttgacgaac ctacgcattt catatcagta ccctaaccca ttcctaagca caagatagta
     1681 agctcacccc ggatgaacca tgaaacaaac catctcctcg ttctcaacat gcattttcct
     1741 cgtcacccag ttactggcag ccttactaac cccgtatgca gccccgggaa agaattcctc
     1801 ctcgagaccg ccgatactcc ccaggaagct actaacactg acaaacatcg gcttcgtgct
     1861 cttcttcagc atgtcataca caccctggaa gaggcggatt gtgccaagcg tgttcacgtc
     1921 caagtgcgat tgcacagtag agagagggat gttgtcgacg cggtgggtgg cgtcgttgta
     1981 gtaccctgcg ttggaaatca cggtgtcgat gtgcgtgatg ttgtgtttcg atttgagggt
     2041 ttcgatggct gtagtaattg aggtggtgga ttggatgtcg aggggaagga ggatgagggt
     2101 tgaggtgggg gatgttggtg gggggttagt atagagagag ttcgtggtgg ggttgcgcat
     2161 ggtagcgatc acagtggtgt ttgggaggag caggagagtt tgggtgaggg cgaggccaat
     2221 ccctggatta ttttgtgggt aagctggacg aagagggtgg tgtggtatgg ggatgagaat
     2281 aagaaaagtg gtgtgtacct ctgctggccc cggtgatgag gtagatggtt ggggatgaca
     2341 ttgtgggatg tgagtttgcg tgggattggt gatgcttgat gtggatggat acagaattga
     2401 gatgtagaaa ctaaatgaat atcttgaggt gtgaatgtat aggagagtaa tggggtctgt
     2461 ctggtggagg ataagcgatg catttatagt tattcgtttt ggggctagct aagctgagac
     2521 tagggcaaga aaggagctga cgagtcgtga cttgtggtgg gatacgagct ttccattcct
     2581 ggcatagcag tacagtctct cgctaaaccc tgttacaggc ctgggtatat agagcactgg
     2641 atgatacaat tctgattact gactgttcct agaccatagt tgtatgtttc aggccccgca
     2701 aatcagcttc accctaagaa ttaagttgta tcagtattcg tccattccat atactactaa
     2761 atcatatgtg atatggcatt gttttcttgc cgtcgttctc aatcgtttac tgtctactag
     2821 ttattagact ccgcgcatgt cctgatagat gcagaagtga ttttagctgc gatgaagccc
     2881 actttctgta taataagggt cttgctcggt ctcggttagg gactatcgca agccttaaga
     2941 ggatgagact gcttggcctc ttgaatagtc attgaattct actatttgat tatggtaaga
     3001 aaatgcgttc gcatgctctt catatcgctg ctctctgtac gagtaaagca gcataattgc
     3061 ggggaaagcc tctatagtct gctgatgagt aaactcctct cctcttactc gagctttact
     3121 tctgtactct gagtttcaag taaacgtcct ctgtaggtac aattgaaccc ttcccagccc
     3181 tgtccctcga tgccttgagt gaatctgaag attacgaatg aatttatccc ggaacctgca
     3241 aaaatgtgcc actcccggag atgattgaaa tgtgactgac taaattagaa agggttcccc
     3301 ctgaacgcat tggaattaca tacctgaagc ggagtaatgt atctttcaaa atgtgctgtg
     3361 gcgtggccct cggcgtctga gtgacaatgc acgatagtgc aaattgttcg aacgctattg
     3421 ttctgaaatt taatctcctc gaaattgaaa ggatcccaaa atttccagat ccgtacttgt
     3481 tgtaaacttg ggaactggac agtgtctaag ccatcaggtt tgcggcaata gtctttcagt
     3541 gtagcgatct tgatgtatgt tgcgtatatg ttccggcgtg cttctgggat tttatcaagg
     3601 aggtccagaa catccctaca agtacttggg gaatgacagg gcatgggatt tctccatagc
     3661 caacgcattg cctctgagaa ccataatttg ctgacgaggg cgcaagaaag gagttgacta
     3721 cacgatcgtt tgtcgtatga atagaagcac gcgaagacct gactcaagat ttcgggaatc
     3781 gcaagcgcac gctgaacggc tgaaatatta aggtgctcat tgttcagagc catttccaga
     3841 ttgtacaatg tgacaaactg tcagtatgga caaatgtaag ttaataattt ttggagattc
     3901 taggcgctcc gtaggtgata ccttctatcg ccacttggct gatatgaatt gtccaggacc
     3961 gggggaagcc acagataaat gaacaagtca ataaaatagt agaagggtta taaggaagta
     4021 atcatagaag taagttgcag atttctggac aaagtagcat ccacgatggt ctttatcata
     4081 aagaatgcct gatgacaagt gtgaattggc atagaactca ggtcagacag acaatgaact
     4141 aaataactat atagaacagt tcatacagct aggcacccgc tctgctgcct gcaagaaaac
     4201 atccctttca ttcctcgcag agatgacctt tttccgggga tgtagagatc ctgatagata
     4261 cgatcaacct tgccccgttt ccgatgtcct aagtggactc agccacataa ttgtacacaa
     4321 ataagaaaga aaaagtagta cctgatgctg ctcggacaca attggatgtc aagaaaagat
     4381 atgtgatcta attccgtagt tcctggcgat tcacctgcag gtgaacatcc ctatcgttgc
     4441 cttaggcaga aacatattta gctccatttc gggtctagcg ccaccagctc cgaggccatt
     4501 ccaagatcca gactccctta tctcaaagac cactccaact gcacaacgcc attacctccg
     4561 cgtgctggaa aatgtcctac gccgttgaaa cgaagaagcg caagtttcat cgagttctcg
     4621 agtccctaac caaaccgtca acctccgact caacaaaatc agccaccgcc gaagcgccta
     4681 caacagctcg agacgcatcg aacaagaaag cccgtctaga tgcgcccaac ttctcacttg
     4741 cacgaaattc acttctaaag gtcgcacgcc ccagctccag agactcttcg gtatcgtcaa
     4801 cctcgcgacc gagctttgtt ccttgggatc gcgaacgttt tctcgagcga ttggaaacct
     4861 ttcgtcgcgt cgacagatgg gcacccaaac cgtcagcaat tagtgaggta gaatgggcca
     4921 agcgcggctg ggtatgtacg gatgtggccc gggtaacatg tgctgggaac tgtggtgggt
     4981 cggttgttgt caagcttccg gatgagctgg acgagttgga tgggttcgat gccgacaagg
     5041 tgcaagagag gaaggaagtt cgtgagtttt ccaattgccg tgtctgcttc gtgcttctaa
     5101 tgtaaatcag gagccaagct tgtagatgaa tacgtggaac gactggtcaa ggggcacgga
     5161 gagacttgtc catggaggaa caagggctgt gatggtgtgt tttctgatat ttgtggttgc
     5221 catttcgtga gctgattgtt acagctacta ttcatcgatt gccgctagca aaccccgaca
     5281 tagccatttc tggcctcgaa aagcgatact caaacctcat caagatggcc gatcaattgc
     5341 cggcagcaga cgtcatccac acgcccgagt ccttcgatat cgaagcactc attaagatac
     5401 ttccagcgag ctttaacggc cccggagaaa gtacgcgcat ggaaagcatt gagaacaaca
     5461 ctgagggtga aaacgggaaa gagaacgcac ataactctga gcctgagccg tttgttccta
     5521 ggaacgcttt catattggca ttcttcggct gggactctgt cccggacggg acagctggtt
     5581 tggtcggctg tagcgtgtgc ttccggagat tgggcctgtg gatgtacaaa ccaaaggcca
     5641 acggggatga ggctctttac gactctttgg aagtggtgaa cgagcatatg gactactgtc
     5701 cttgggtgaa tgggaaggct cagagtggaa caggacgggc caccgagaaa ctagaaggcc
     5761 tacgttccgg ctgggagctg ctgggccagg cactcaatgt gcgccatcgt cgactgaatc
     5821 ggtcgaccac ctcgggagac agtcgtgctg tctctgaggt accatccacg gatgagcccg
     5881 tggtggacga tgtgaaccca gaagttaaaa aggccagtga ccgggaatgg tgggccaagt
     5941 tacgccgcat gcgacaggtc ttgaacgtca gttcgcctag gaagaagccg acttcgcagt
     6001 gatatttttc atcattctgt acttctgcac atgatactcc tcatctggtt gttaatgcag
     6061 cgtggcgttt gggcatcatg tctatcttct cgatatcctt cattcctaca ttagtcattg
     6121 ctatagcgag cctttgtcat ccgcctcgat aaattagaat acagccatac tcaatcagag
     6181 aaagatcgga gaacaaaagt tatcatttac tcaacgacat aagaagcatt gctttgaagc
     6241 cagatgcaca acccgccaag cgtaattaag ctgaagatta taagcaccca ttgaatctgc
     6301 tctctctttc ccttccgcct gtacatctcc cagcccggtc ctgagcgccc tggcaaaggc
     6361 agaaaagaaa caacctctgc atctgccatt actttcgatg ccaggtcagc aggaaggttg
     6421 ccagcataag gagcccaata tcgtccaaag acggtgttga ggatgccatc tcgggcctga
     6481 atccgagaaa ctgaagccgc ggtgcgacac atgcctacca tgcgagagta tcgagtctcc
     6541 tgatactgct ggaggagatg ctgaacctgg gaatttgacg gtttgcaaac tccgcgggcg
     6601 ttgatgagat catgtagaag ggaggagagc gcggcagcat cctcgatggc acaattggct
     6661 ccctggccaa agttgggcgt catctgattg cagactaagt aagccgaacg atatcacttc
     6721 aattctctta gccacgcacc ttgtgaacgc tatcgccgat caacaccatc ctttcatggt
     6781 gccacgtctc aaacaaaccc tcctccagcg ctgtcattga ggatacctct ctgtttttcc
     6841 acaaatcccc cacacagatg tctttccaga accgcacgtg cttgacccgt tcgaagagct
     6901 gtacggcatc ctcgtctgag aaccgcggga catcagggta gacgtacttt ctatccaact
     6961 tctggatcac gaaccagaac acccgaccat gtctgccgtg gattgtcaga atggatagat
     7021 ggtcatagat cccgttgatc tgttcgctta tctcgagccc tgggatggcc gacgagattc
     7081 cgaaaacgca gacatattca acagtcatgc ctgcttatgt tagtgttgat tgaacccagc
     7141 acaaagaagg tgagggacgg caaatacttc ttctttcacg cctcgaaaca gatgcaggcc
     7201 gattctcccc ggccattttc cagatctcac ttctcacccg actatgtacg ccatccgcac
     7261 caaccacgag atccacctca tactctgtcc catcagccac agcaacagta attccatgct
     7321 ccaactgtcg cacttcaact acccttttac gggtgagaac gttatgtttc tttgtcagac
     7381 cctcatatgc aatttgcagg aacttctgcc ggtccaagaa cgcaaccgga tatccgaacc
     7441 tataatctta gccacagcac cgtctctctt ctttgttcgc atactggtaa acgcagagac
     7501 tattgacata cctatcgccc aaaaccttcg gatagacgtt gctgaagcag aacccatctg
     7561 gatagctaat attcgcctga tgcaacggct caatcacacg ctcgatctcc ccaaacaggc
     7621 ccagttgctc gagaatccgt ccgccatttg gcataatacc tatcgaggca ccaacttgcg
     7681 gggcaatatc gtctcctttt tcgagtatga ggtactcaat attggcgcgt tccagacagt
     7741 gcgcaagggt gaggcctgcg acagaaccgc ccacaataag gacgcgaaat tgaggttgct
     7801 gggtattggc catacttgcg gatgtcgcca gtaaccaagc ctcaatcgag gtaaggctca
     7861 cttatggtat aaatatcgtg ttgatacctt tacctcaaaa gagattgcac ctaatgcaga
     7921 aagattccaa actgcacggt aagccaagtg tttgctattc tcactgctgg aacgaatgac
     7981 cctcaagcga aatccagcac tgccattgtg gcagaactgc gtagtcaagc tacttcggct
     8041 tatgcaagcc agtctcgtgg tacatgcact ttaccaatag ttgctgtgtg tcacaagcgt
     8101 ggctgttcat catgccatcg tctacttgca atcataaatg gcagaaaggt aggtatgcct
     8161 tgctttattc tgcacagctt aaaaggacag ccacatgtgt caagatagca tatacactgc
     8221 tttatcctgt tattaaatgc ttttcttctg ccggcccaaa cctgtctatt gcatgacacg
     8281 cagaaattcc gttctcgtga cagcactaca agcagtggta caacaccgtg aactttctcc
     8341 gccatgccgc cagaataaat agctgtgtgt tgcacatgcg actattttca taccgttcct
     8401 ggctaccaat tccggtgata tgacattttc ccgcagctta ttcctgtctg atgcatctac
     8461 tacgcacaat ccctcaacaa agcatctatc tctccttgtg cttgattcca cgctgggagc
     8521 tcttctcttg tcgcttgaca gaacagaata acacgccata taggatctcg aagagaaaga
     8581 acatggccac ggaccatatc acgagtgggc agtttatata cgaaaaagcc tcccaccaac
     8641 gaaaatatcg aacaagggca aagccaatgg ctgacgttga tccaaagaac ctcgagatcc
     8701 tagtgaacgt tcaacacaac tgattctcaa accaggtcag acaaatactt accatagcgt
     8761 ccacgatgcg cctcgggtgt ttccgcgact caataattga aatacattcc ctatgctaat
     8821 aaagagctga catgcaattg ccccccacgt ataggcttgt gcaggaccaa cctgggcagt
     8881 aagagccata tgcccactca gacaacaaag tgttgttgct gcgaagacga gagtcatatg
     8941 gttcctcaca attgcagagt ggtgccattc atttggggca ttcttgattc ccgcgtagat
     9001 aactccaagg tcgagtgaaa tgccaacaag aaaggcaacc cgctcgataa tgcctttggc
     9061 aggatacatt gtgcagaaaa caatctccca agcaaaattg atgcaaaggc ccccgatggt
     9121 catgcagtag gtacggtccc tgaacgatgt gtgaatcatt tccacatagt gagcaaccca
     9181 gccgacagcc attccaacaa cgaaaatatt ggcgagccat ttaagctcgt tatattcctg
     9241 aggagcagta gaatggtcga aaccatccat taaagcgaaa ataagaggca cttcaatgct
     9301 gaatgaattt ggtcgccgtt gagatctgag tcacttgtct cttgcatgac ctgagcgtgc
     9361 ttatatagtg agatgacttg cggtcagcta gtgatacggc gccatggttc tgttctgctg
     9421 acggtacgcc atgaaggtct gtcagtctcc ataagtagac tgatgtccgc accaggtagg
     9481 accaccagga gtctcggtaa ttatgtgtca ccagtgcgct attctcaagc ccttcaaagc
     9541 cctgcaagac agccagggga gtgcaccagg cttcaaaggc tgtatctcct gccgtgccgc
     9601 taaagcatgt cgccataccc aaatgtcagc ttctatcaag agatagagtc aggcaacaac
     9661 cgttctggcc ggctcgaccg cacagaaggg gagatggtgt aacttgtgcg agaaacagct
     9721 tgtgcagagg agaaccctga gccattgacg atgagtgtac ggctgaagta tcctgtctat
     9781 agcatacata tatagacagg agaacgtccc tttgcgagcc cattggggta ccgcgctgtc
     9841 atccgttaac cttcttatcc ctgcatttcg tcccactcag gaaggaccga atcatggcgg
     9901 cactgccgga cgttgcctcc attccccttc ctctggtggc aaccctggga attgcccctc
     9961 tagttttcta tctcgtcctt gatagatttg gccctttgtg gccaaactcc aaaactttct
    10021 tgattggaaa gaagaagccg gagaccgtga catcctttga gtgcccatat gcctacatcc
    10081 ggcagatcta tgggaagcat cactggaatc cattcgtgca gaagctgtct ccaaggctta
    10141 aggatgagga tccagccaaa tataagatgg ttctagagat aatggatgca attcacctgt
    10201 gtttgatgct agttgacgat gtatgtatac cgtgggccta tataaataca ctctaacatc
    10261 aagcagataa ccgacaatag cgactaccga aaaggcaagc cagcagctca ccggatatat
    10321 ggcccttcag agacagcaaa ccgcgcttac taccgagtca cccaaattct caatgagact
    10381 gtgcagcggt tccccaagtt agccaagttc ctgctacaaa atctggaaga gatcctcgag
    10441 ggccaagacc tgtcactgat ctggcgacga gatgggctgg gtagcctttc gaccgttccc
    10501 gaggagcgag ttgcagccta ccgcaaaatg gcgtcattga aaacaggggc gctattccgg
    10561 ctgctggggc aattggtgat ggaggaccaa tcgatggacg ggacgatgac tactcttgcg
    10621 tatggctcgc ttggtttatt gcatatcaca ccaagtctag ctgaagctga agctgacctt
    10681 gagataggtg gtgctctcag ctgcagaacg attgcaaaaa tgtctactca tccgaatatg
    10741 ctaaggccaa gggagcactt gcagaagatc tgcgtaatcg agagctctca tatccaatca
    10801 ttctcgcgct ggaagccccc gaagggcatt gggtcgccag tgcattggag accagctcac
    10861 cgcgcaatat ccgcaaggca cttgccgtga ttcagagcga gagagtgcgc aatgcttgtt
    10921 tcagggagct caagtcggcg agtgcttcgg tccaggactg gttggctatc tggggacgga
    10981 acgagaagat gaatctaaag agccagcaga catagctttt cagtgttttg aggcatacag
    11041 tttctcttat ggtttgaggg ttgagaaatc attcttcttg agatacgttc tgggtttaat
    11101 ttgtgctata catatagggt tagatcaaaa cagcatatat taacatttat acgttggagt
    11161 ccagttcatt caatgagcaa tgaattggtg tgcgatattc ctgtcatcgt caaaacttac
    11221 attgaccctg gaataccgtc cagcctgctt cggatgaagt aatgccatat atatagtccg
    11281 agcaggttgt ggtagcatca agcaagccac agagggggta cgtgcatgaa ccatgttaca
    11341 tttcggacaa ccatcagctg gtgtatccct gcttcgccaa cacatctatc agacgtagga
    11401 ttcaggacag cctaggaaat ctgattgatg ctggcgctgc gctcaccgca gccactattc
    11461 tttctactcg cttcttcgcg acagtgcttc gtgttcaatg tctatgtaca gggcctctaa
    11521 ggcggcgttc gcttcataat caacctattg tgtacaggct tactgtgcta gagctaatca
    11581 acagagctta tgcatgggct gtcatacctg ccataatgtc tccatacccc atatccacaa
    11641 ccaaacaatc aggggttact tcccttccct atactaatat tgatccccta tacactcccc
    11701 taccaaacaa cccatcactt tattacttta agcccccata ccatcttatc ccaccaaaaa
    11761 caacacgatg accccacccc tcctcccaac atccctcatt tcagccatcc tcggcatcac
    11821 cgcccaccta acatacttca tccacgccga cctcgagaag cacgtcgtct tcctggtcaa
    11881 ctgcctcatc ttctggccct cactcggtct aatagccctc tttatcctcg gctatagaga
    11941 tatttctcaa tggatcggac cagcaatact gagctttcac ttctcgctgt tagcttccat
    12001 agccatctac cgatacttct tccacgcgct ggacgggttt ccaggtccaa agctggcaag
    12061 gattacagcg ctgtgggatt tcaagaatac ggtgctgaat gcgaaatggt atatcaaggt
    12121 gaaggaaatg catggggtgt atggggatgt tgtccggatc agtattcctc ctctcttcca
    12181 ctcttcccat gtgatttgta cagggccaat tgattgaata gaacctaggg aattatccat
    12241 caacgaccca tctgcgatca aagatatcta cggcgtgggg accacatgcg tcaagggacc
    12301 gttctacgat ctacattatc cgcatcgatc gctgcaaatg gcgagagata aggcgtttca
    12361 ttcgaagagg aggagattgt gggatcgggg gtttacgtcg aaaggcaggt ttgacatgca
    12421 tgttctttga atcttatatt gactggctgc tgtaatgact agcactcgct ggctacgaac
    12481 cgtatcttct ggagcactgc aaagatatag tccgggttat tgaatctcga tcatcgcaag
    12541 cacaggaggc gacggcacta attgatggct ttgcgtggga ctcgatgggg atatttgcgt
    12601 ttgggaaatc gttcaatatg ctgcatgggg aaccgccaaa gatgctgcag atgatgagga
    12661 tgatggggcg cggggcgagt gccttattga gttcgagctg gctggttata ctcatgaggg
    12721 ggatggtggg agtgaggcgg tttacggata gatggttaga gtggtgtgcg cagtgtgtgg
    12781 aggagaggag cagggtatgt atgtttgcag ttactgtctc tcttcagttg tggatggtat
    12841 aggctgatgt gtttcaggtc gaaactaatc gccgggatct cttcagctac ttgatcgaag
    12901 agttaagctc tgagggagac cagtccatag gtggcgttga cggggatctt gttcgcgatt
    12961 cagagctcgc tattacggct ggcagcgaca ccgcagccag taccctcaat gctctgttct
    13021 atctcctggc acgacatccg gacaagctgc gccggctgca ggaggagata gacactgctg
    13081 ttccagctga tgaggagctg tctcatgcgg cgttggtgaa gaagccgtac ctggaggggt
    13141 gtataaatga gagtctgcgt ctttgtccgg ctgtcttgag cggattgcag cgtgagacag
    13201 gaccggaagg gctccgaaca gcgggagtct atattcctcc agggatgata gtgtctgtgc
    13261 cgacatatac ggttcaacga ggtagatcat ttacctttcc tgtgaagata agagctgatt
    13321 tcctttcacg aagacccgcg caacttcccc cgtccaaacg aattcatccc agaaaggtgg
    13381 tccacccagc cagagctagt cattcataag gaagcactga acgcgttctc aagcggcacg
    13441 tactcctgtg caggaaaggc atttgcgatg atggagatgc gactgctcgt ttccacgatt
    13501 gtaaggcact tcgacattga gtttccacca ggggaaggac aagaaccgct agatagattg
    13561 ggaggaacgg ggccattaga ctgtttcaca acacatattc caaagtatca tctactcttt
    13621 aaaaagagat agatacatag atagattcca atacagtgtt gtgttaccca tattgatcgt
    13681 aggttgtcat ggagtgtagt gaccgtaggc atctaccgtt actgtttcac tccattcaca
    13741 ggccgcatcc ggccaggcag gaaacacgat taaggcaggg gtttcaacca aggaactcaa
    13801 cttaagcagc acgaattccg tctgacttca actgctttat ccctgtctaa ctgctacgcc
    13861 tttcatggag gtttcttatt atccctttac ttccgtctca cttgatcatg gcctccaaag
    13921 aggaagagcg cacaggccaa cggcccagca tcagcatgta cgatcccgcc cgagaccgct
    13981 gggaggagca gcctgttgtt cctgctgaac cagcgtcagc ttctgcttcg atcgaagcaa
    14041 caccaactca gacaagtgaa gccaaaccgg taagttggtc atttctgttt agatttagtc
    14101 cactcgagaa ctgtctccct agtggagaga gcaagtggag tcctgcagcc catccactgc
    14161 gaactaaagt ggcgcttacg ctcggcggag gcggtgatta ctattcttcc cgcaaataaa
    14221 agactccgaa agaaaatgct cctgcgcgtc tgtctgtcta tctgagcgtg atatttctca
    14281 gtgttccata ttctttccat tgcaggatat ttgacgctga ttgccgatgt ttattgggtt
    14341 tttcatatag gttcatgatt ctactgtgac ttctaccagt gaatctcttc atcttcctca
    14401 aactaccacc atcgagcctt ctcaacaacc ggagcagcag cagaagcagc ctcctatccc
    14461 gacacctcca tcctctcaat cacgccgcaa acacaaaata aacaaaatgg gtgactacta
    14521 tcgctctggc tctgcggatg cctacgctga gcagagctct cctgctgccg atagccacaa
    14581 gcgcaagcta gaggacgaga catcggagca gcagccaccc gccgaccaag cgaacgaccg
    14641 tcccatctcc aagcgtaagc gtctcgaaga acgacaccag aagctgcgga aacgcggcca
    14701 ggcacctccc tcggcttact cgcgccgcga tggcgacgag acagcagcac gcgcagcacc
    14761 acggccccga tcaccctcac cgccccttcc tccgcggtct ccgtcgccgg aagtgcaggc
    14821 gcgtcagcgt aaacgacccg gtggcggtgc gcggcgaggt ctcgtggacc cgcagacact
    14881 gcggcggcga caggaggagc gggagcgcgc gctggaagaa gatgcgatgc gcaactcgca
    14941 gagccgggga gtgacggata tcgtgagaca gcattacaat gcggttccgc agcggggccg
    15001 ggagtggcgc aagacggaga gtaagatcaa ggggctgcgc agtttcaaca attgggtgaa
    15061 gagcacgttg attcagaagt tctcgccgga tgaggagttc gtggcgcggg cgattgggac
    15121 gaaggactgg gcggatggaa ctgggccgcc gccgatggag gagaaacggt tactggtgat
    15181 tgatctggga tgtggtaagg gaggtgatct tgggaagtgg cagcttgcgc cgcagccggt
    15241 ggatctctac gtgggactgg atccggcgga ggtgtccatt atacaggcgc gcgagcgata
    15301 tgcggggatg cgttcgggca ggggacctcg tggtggacgg aggggagggc cgccgttgtt
    15361 tcatggcgag ttccggtcca aggattgctt tggggagtgg ttgggggatg ttgatattgt
    15421 tcagcaggtg ggaatagatc cgaatgttgg accgggaggg tcgatgatgg cgtcgcgatg
    15481 gggtgggggt gggtttgatg tggtgacgtc tatgtttgcc attcactatg cgtttgagag
    15541 tgaagagaag gctcgtcaga tgctgcgcaa tgtggcgggg tgtttgaaga agggtggccg
    15601 gttcatcggc gtgtgtccca actcggacat tatcagtgcc cgcgtggccg agttcaatgc
    15661 gaagcgcaag gaccgcgagg cggcgaagca ggatgcagag ccagaggacg gtgaggtgga
    15721 ggaggaggcg aaggcagaat gggggaattc gatctatcgg gtgcgattcc ctggagatac
    15781 gccggaggat ggcatcttca ggccgccgtt tggatggaag tatagctact tcatggagga
    15841 agccgtgggc gagatcccgg agtacgtggt gccgtgggag gcgttccgag cgtgagtcca
    15901 ttcgatattc catggaacat tgattacgat actaatgaag caggttgacg gaggagtaca
    15961 atctggagct gcagtaccgc aagccgttca tggaggtgtg gcgggacgaa aaggacgatc
    16021 cggagctggg gccgttgagt gagcggatgg gcgtgagaga tcgcacgaca ggcgagttga
    16081 cgatgacgcc ggaggagcag gaggcagtca gtaagtatac acccttaggt tttacttcag
    16141 ctgaaggaga gagtgctaac gggacaggtt tctatcatgc attctgcttc tacaaggtgt
    16201 gaaggataag atacatagta ttagaattag ggtaaatagg atttaatcga cataatcagc
    16261 tccatatcca tacttgcttc aatccaacta tgatacagta taactatccc tataaagtgt
    16321 agctggtatc gatatgatat cgataagata aacttcccca aagaccatac ttcccaaaac
    16381 agcctagcgc cgtgcatcgc gtcgcgttcc tttcaactta tctttatcca taatcgttat
    16441 agcctcaaag aactaccaac aaagaaacct acaccatata ccatataccc tccttcttct
    16501 cctctatcct ccttgccacc tatatccaca acccaccacc cacaccttac ctcaattata
    16561 cactaccacc acaaccaaat aactctcacc caaaagaaat caaccaaaat gcccaaacgc
    16621 tcccgcccac caccaccaac agccaccccc ggaccaagcg gaagaaacag aaacagagac
    16681 agagacacca ccccccctct tcccccctac caacccccca ccagcaccct gacgacccta
    16741 tcccaccaac cgaccaccgc acccgccctc tccgccctcc tcgcaacgca cacctcctcc
    16801 accctaaaaa cgcacctcca gcacgcgcaa gagaaactca ccgacgccgc aggcgagatc
    16861 aacgagcggc tcacagacgc gaaagagagg agtaagaaat cgcgggagag gaggaggaat
    16921 atacgttctc atactttgga gaataataat aataatggtg agggggtaga tgaggaaggg
    16981 ggggatagtg aggacgaggg gattgaagag ttcgaggaga gagtggctca gacgacgaag
    17041 gtattggagg agactattcg gggggttatt gatgcggaag tgagggggga ggagcttggg
    17101 agggttatct cgggattgga gggcggggtt gctgaacggg tgagggttag gggtgtgagg
    17161 aggagtcaga gaggaattgg gagaaggttg agggggcatc atggtgagga tgaggaggat
    17221 gaggatgggg aggaaggggt ggatgtggat gtcgatgaag atgaggaggg cgcggtgccg
    17281 ttcctggcgc agttcgagga tgagctgcgc gggaagatgg aggagtatga agggttgagt
    17341 ttgacgagac ggtatgtata tccccatttc tatcccaata atattttact tccaggttta
    17401 tttactaacg gaatcatggt ggtaggtatt ctacgaacaa ctcctacata ggtttctaca
    17461 aaatcatcca cgaagccaaa cacatcggcg acgaaatccc ccctccgcct catccgtcga
    17521 cgtggttcgc tcacttggaa gatcctcatt ctcaatctca accacaatct catccatctg
    17581 cctctacctc tacttcaacc actaccacca gacaaactag acccacccgc gctcgacctc
    17641 aacccccctc cgaagaagaa gatgaagatg atgatgacga aatcgccatc caaactgaac
    17701 gcatatcgct gaaatgcccc ctcacactcc ttcccttccg cgaccccgtg accagcacga
    17761 aatgcccaca cagtttcgag cgcgaggcga tattcaccat gattagcggg agtaatcaga
    17821 tggtgcctga tccgaggggg tcatctggaa ctggaagagc gaagcgcgtg cgcagcgtca
    17881 agtgtcctgt gtgcgaggtg cagttgacgg agtttgatct gcggagtgat cctgtgctga
    17941 tgaggcgggt gaagagggcg gagatggcgg agttgaggag gagggagagg gagatgttgg
    18001 atgatgggga agatgatcag gatggtggtg acgggggtgg tggtgggggg aagaggaaga
    18061 ggagtgggag gaggaggggg agtgcggttg aggttgatga tggtgatagt gatgatgata
    18121 gtggtgagga tgatggggtg gagaggattc gggttaagag ggagagaggg atgtctgttg
    18181 ctgctaggat taagcaggag agggcggtgt cgatggttgg ggatggggat ggggatgtgg
    18241 aggaggttga tatggatgaa gaagggggag gggaagaggg tgggtatgat tctatgtatg
    18301 atgagtgatt tatctagcta ctacaagcat tcatgtttct attctgtaga agcatacaga
    18361 gtagacttat ttattgccta tctctatttg aatctctgct atgtagttgc aataatcacg
    18421 ggtataataa atacaaacag ccattgaaac catcaaccat ccatcgaaac accatcctcc
    18481 atccacaatc attagggcat ttcgatcttc tcctgcatct gttccagaca gtgcaaccag
    18541 atccgcacct gtgcaataat caccgtcaaa cgacagcaac cgcggcattt ggaaaaaaaa
    18601 gttcaagtca agtagttgtc gacaagccaa caatatcatg ttgaatcaat gctgctactt
    18661 ggtaatcaag ttcagataat cggccacgat aagcgtcacc atcctgtggg tctggggtta
    18721 gccaagggca ctagtctgat agaaaatggt ggggacacta acgcatgagg agcgatccgc
    18781 acatagtacg ttccgaaacc gcggtagaac cgcaaccagc cctcctcctg gacgaccttg
    18841 cgcgcgcaat ccaagacgcc cttgtagggg agccgaccgg tcttcggatc cttctgctgc
    18901 ttctgcaggc gagtcttgac aaagtcgaaa ggcagggaga ggaaactggc aaagaatccc
    18961 gcgatagcgg acgcggcaaa ggtctggttc tgagtcgaca ggctagtgtg cttcttcagc
    19021 tgcgccttgg actcggcaaa gaaggtcaac tggccgacgt tgagcgccat ggcacggatg
    19081 acggtaggga aagcaccagc ccacagagcc gggacacctt cgtgcttgga gatgcggaag
    19141 agcgcgtcca tgacggagcg gtagttggcc cgcgcctcgg gaggtttgag accgtctgac
    19201 tgcatacgca ccagtgccag atcggccggg ttgccaatca tggcggcaat acctccggca
    19261 gctagaccgg caccggcacg ttcggcgaag gtgacgctgc ggttggcggc ttcggcacgc
    19321 ttgttgagag tcttgctgaa ggtgtcgaag aaacccaggc gggcggtagt gtaaacggcc
    19381 tggcgcagca gtccagccga cagaccggtg tacagatcaa gtgctttgcc tgaggcaatg
    19441 atgtcgcggg ccacgccaaa ggcagacggg cggggaccgg tgcgcacacc ttcaccggcg
    19501 agctgcaaac ggactttgat catgtcgatg ggctggatca cgaccgtggc ggtcatgccg
    19561 gccaggccac cattcacgaa gggaagagca gcacgggtgt aagggtgatg gaggaaatcg
    19621 acggcgggct ggggctcttt ggccgcggtg ggggaggcca t
//
