LOCUS       OGUI01000016.1         45098 bp    DNA     linear   PLN 19-AUG-2019
DEFINITION  Aspergillus niger.
ACCESSION   OGUI01000016
VERSION     OGUI01000016.1
KEYWORDS    .
SOURCE      Aspergillus niger
  ORGANISM  Aspergillus niger
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus.
COMMENT     'Annotated using funannotate v1.6.0-df4262f'.
            ##antiSMASH-Data-START##
            Version      :: 5.0.0
            Run date     :: 2020-11-02 07:37:12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1115791
            Orig. end    :: 1160889
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..45098
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="join{[1135221:1135422](+),
                     [1135489:1135634](+), [1135689:1135958](+),
                     [1136007:1136370](+), [1136421:1137364](+),
                     [1137422:1141747](+), [1141800:1142473](+),
                     [1142534:1142683](+)}"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      join(19431..19631,19699..19843,19899..20167,20217..20579,
                     20631..21573,21632..25956,26010..26682,26744..26892)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..45098
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..45098
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T1PKS"
                     /region_number="6"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     mRNA            complement(join(1..928,984..2099,2154..3124))
                     /gene="PAN2"
                     /locus_tag="ATCC64974_90300"
                     /product="poly(A)-specific ribonuclease"
     gene            complement(1..3124)
                     /gene="PAN2"
                     /locus_tag="ATCC64974_90300"
     CDS             complement(join(1..928,984..2099,2154..3124))
                     /codon_start=1
                     /db_xref="InterPro:IPR012337"
                     /db_xref="InterPro:IPR013520"
                     /db_xref="InterPro:IPR015943"
                     /db_xref="InterPro:IPR028881"
                     /db_xref="InterPro:IPR028889"
                     /db_xref="InterPro:IPR036322"
                     /db_xref="InterPro:IPR036397"
                     /db_xref="InterPro:IPR038765"
                     /db_xref="PFAM:PF00929"
                     /db_xref="PFAM:PF13423"
                     /gene="PAN2"
                     /locus_tag="ATCC64974_90300"
                     /note="MEROPS:MER0030317; GO_function: GO:0005515 - protein
                     binding [Evidence IEA]; GO_function: GO:0003676 - nucleic
                     acid binding [Evidence IEA]"
                     /product="poly(A)-specific ribonuclease"
                     /protein_id="ncbi_ATCC64974_90300-T1"
                     /transl_table=1
                     /translation="MKKSRYLCAATDTGSVNALSLNDFSVVKSWKAHGTAVNDMDARND
                     LLVTCGFSVRHLGSPIVDPLANVYDLKTLSPLPPIPFHAGAAYVRMHPKLHTTSFVASQ
                     TGQLQVVDLMNPNAINLRQANVSFMLGIDLSPSGEALAINDAECAIHLWGSPAKVHFNE
                     MSKEAEFGDVAPRPPTLDWSPETPLSMIGMPYYHERLFSAWPSHLVFEVGSPPPQVDQA
                     LIPYLRPAELGHHAPNPKKTRRYQVENTRALASAEPALIAPKFLSEKAREQNKAKSEGA
                     ISDAAEALAGAKINGETDDDPLLKYSNVEIKYSRFGVDDFDFRFYNQTTFSGLETHIAN
                     SFTNALLQLFKFIPYIRNVALHHAASSCIFETCLLCEMGYLFDMLEKASGQNCQATNLL
                     KTFSSYREASNLGLFEENLTNKSLSAAIQAVNRFFLGQISHDFRMISPSSDDLDHRLAT
                     VASESIRCMFCQNEIVRPGNSLVNELNYPAIDIKQARRNPAFRFSNILRASIEREAQNR
                     GWCNYCRRYQQVAIRKSVHRMPQVLMLNAALTNPICRRLWAIPGWLPEEVGIVIEGGQI
                     LCFEGEDLKLRVQAKMPGLVVYDLVGLVCEIDIPEHQKAHLVSFINVSISSREPEAKNK
                     WHLFNDFLVTEVDKEEALRFNQPWKIPCVLAYQVQDGRHAMDDTWKDALDTTLLFRDWS
                     LNGGRPVESRVTLSEEEKPTPGTPVALDTEFVDLEKAEIDVKADGSQEIVRPSKSGLAR
                     VSVLRGSGIREGVPFIDDYITIKENIVDYVTQYSGIKPGDLDPRVSQHNLVPLKVAYKK
                     LWLLLNLGCVFVGHGLASDFRKVNIQVPKSQTVDTQYLFFHPGKNRRLSLRYLAWAVFK
                     EYIQEEPADDSQGHDSIEDARMALRLWKKFKEYEDAGIVSQILEEIFREGSKLGFRPPP
                     RNGVPTVLSRPGTAVTMQNNSGRNTPSTSDVAGAAASAPATPRQAFRRSIALTPSNGSF
                     AGPGTGDFFSGSPLK"
     mRNA            complement(join(4776..5233,5295..5437,5499..6114,
                     6171..6417,6482..6577))
                     /locus_tag="ATCC64974_90310"
                     /product="hypothetical protein"
     gene            complement(4776..6577)
                     /locus_tag="ATCC64974_90310"
     CDS             complement(join(4776..5233,5295..5437,5499..6114,
                     6171..6417,6482..6577))
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002974"
                     /db_xref="InterPro:IPR017972"
                     /db_xref="InterPro:IPR036396"
                     /db_xref="PFAM:PF00067"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 271.5; E-value: 2.3e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC64974_90310"
                     /note="EggNog:ENOG41; GO_function: GO:0020037 - heme
                     binding [Evidence IEA]; GO_function: GO:0016712 -
                     oxidoreductase activity, acting on paired donors, with
                     incorporation or reduction of molecular oxygen, reduced
                     flavin or flavoprotein as one donor, and incorporation of
                     one atom of oxygen [Evidence IEA]; GO_function: GO:0005506
                     - iron ion binding [Evidence IEA]; GO_function: GO:0016705
                     - oxidoreductase activity, acting on paired donors, with
                     incorporation or reduction of molecular oxygen [Evidence
                     IEA]; GO_process: GO:0055114 - oxidation-reduction process
                     [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_90310-T1"
                     /sec_met_domain="p450 (E-value: 2.7e-61, bitscore: 203.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MAFLNSVAPSLIVGTWICALAYRFIAQKRELRANNKVAAANGCLP
                     LRQWNSTWPLGLDLLVQAFHYDRRQQILKFFLGVVAESGTTFEQNLLFSRGVDTIDPQN
                     IQALLSTQYADFGLGLRPPTFCPLLGSGIFTQDGAQWRHSRERLRPQFMTNRFTNFEQI
                     RSAVDNLISSISDDNAVNLQPLFFRLTFETTLFLLFGQHLPSLQLEGIKNQESDFANAF
                     NLGQEYLAKRGRLGGFYWLLDGRDFREACKTCHEFVDRAVQKALDLTTKKTPGTKTEPY
                     IFIDAFIEETRNPEVLRDQCLNILLAGRDTTACCLTWTLRLLVQHPPVLSKLRAEISDT
                     VGIGPRSPAPTIIQVKSLPYLSLVIKEVLRLYPSVPVNSRAATKTTTLPTGGGPTGTAP
                     ILVRKGEAVGYCVYAMHRRRDIYGADADKFRPERWENDALKDVGWGYLPFNGGPRVCLG
                     REFALLEVGYTIMRLLQTFEVIEQAEGCRMEKGVGDERQVLTLVVSCGEGCVVRMRRYG
                     EV"
     mRNA            join(9267..9397,9447..9713,9783..10335)
                     /locus_tag="ATCC64974_90320"
                     /product="hypothetical protein"
     gene            9267..10335
                     /locus_tag="ATCC64974_90320"
     CDS             join(9267..9397,9447..9713,9783..10335)
                     /codon_start=1
                     /locus_tag="ATCC64974_90320"
                     /note="SECRETED:SignalP(1-16); EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_90320-T1"
                     /transl_table=1
                     /translation="MKAVLCSLAFAVGVAAKDDPDYDPSLNFRPKNVTLSILDYWVGSY
                     YNGTTDVELSFYTGLAANWSHLCPNLINTTVTKKYNNSVLGLTEPSSYNVGYDPVNAFF
                     TMWPRNFNFSTLPDPRWSWESIQYDASLSPTYWVGPRVSNNFNWTLNATQGPPYSLSST
                     LTDYDPLGGWASNLASCNGSDIVEWTFYPTPWDIMGNGLYLPDAVLDLQFDEKTANLSL
                     NGYFIGYHAVKVGTETLSTGVLVVGKMKLSFLGVLDAYHSDVLANNTATPTWLRTVGFQ
                     NNSLNVGYTSTASSVSMGRAVFATIIALTVMAGFV"
     mRNA            complement(join(12129..12428,12488..14434))
                     /locus_tag="ATCC64974_90330"
                     /product="hypothetical protein"
     gene            complement(12129..14434)
                     /locus_tag="ATCC64974_90330"
     CDS             complement(join(12129..12428,12488..14434))
                     /NRPS_PKS="Domain: TD (410-657). E-value: 4e-45. Score:
                     145.6. Matches aSDomain:
                     nrpspksdomains_ATCC64974_90330_TD.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="InterPro:IPR020806"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="InterPro:IPR036736"
                     /db_xref="PFAM:PF01370"
                     /db_xref="PFAM:PF07993"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 67.6;
                     E-value: 2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC64974_90330"
                     /note="EggNog:ENOG41; GO_function: GO:0031177 -
                     phosphopantetheine binding [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_90330-T1"
                     /sec_met_domain="PP-binding (E-value: 4.7e-06, bitscore:
                     22.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.3e-39, bitscore:
                     131.7, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MATPNPPRWCLIAPFALQDLWSSEKGRQALQGLSAVNFGGAPLSS
                     ATGNAISSHFRLQTLMGSSETGYTPTLLCEDPADWACFEWNPAFEHRMEEVGDGLWELV
                     IPRPSSRRYHGIFHAFPHLSEYRTGDLFEPHPTKPHLWRSKGRADDIIVLSNGEKLNPI
                     DAEHHLESHSLVHRAAIFGQDRFQVALLVQPKWDELPETWTPQWLKQALEPLMKDANGL
                     LPAHGQIHHNRVAIASCDRPFALAPKGSLRRRETAQLYEDVINALYSDATGYEGSTRDV
                     EKLQESTMEGIEQWLQETVSRILGGITVDLDVDIVTLGMDSLQVVRLAQVLQDAADRMS
                     QTKQISILWTSAAIYEQATVRRLASTLFRQLGGHLGAEGEKHAVSFWSREHQLTHAIWQ
                     QAQSLQLRGKTVLLTGSTGELGSYLLEELLQDPTITHVYCLNRSADAETRQLARFREKR
                     LADGWLVETSRVKFWQADLSQERLGLTEEEYSYLRERVDIIFHNAWMVNFNLPLSSFRS
                     QLEGTGRLLNLIKDSPRQAAFHFISSIAAVSGRSTILPETDHIAETLYGPSTVLSQGYA
                     ESKYAAEVLCDLVAGETQQTIAIHRVGQLGGPADAEAGMWTTRDWFPALVRTSQTMKEL
                     PDSIGSIPVDWVPIDVAARSIVQIGCGRHSGRLASTESNHAEVYHITNPHISHWEPLAQ
                     IISQACSTKIIPLRVWVKNLTNRLSDPNLNEEVMRKIPAASLLGFFTSLAESEG"
     aSDomain        complement(join(12405..12428,12488..13204))
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC64974_90330_TD.1"
                     /evalue="4.00E-45"
                     /label="ATCC64974_90330_TD.1"
                     /locus_tag="ATCC64974_90330"
                     /score="145.6"
                     /tool="antismash"
                     /translation="VLLTGSTGELGSYLLEELLQDPTITHVYCLNRSADAETRQLARFR
                     EKRLADGWLVETSRVKFWQADLSQERLGLTEEEYSYLRERVDIIFHNAWMVNFNLPLSS
                     FRSQLEGTGRLLNLIKDSPRQAAFHFISSIAAVSGRSTILPETDHIAETLYGPSTVLSQ
                     GYAESKYAAEVLCDLVAGETQQTIAIHRVGQLGGPADAEAGMWTTRDWFPALVRTSQTM
                     KELPDSIGSIPVDWVPIDVAARSIVQ"
     mRNA            complement(join(15850..16553,16621..16759))
                     /locus_tag="ATCC64974_90340"
                     /product="hypothetical protein"
     gene            complement(15850..16759)
                     /locus_tag="ATCC64974_90340"
     CDS             complement(join(15850..16553,16621..16759))
                     /codon_start=1
                     /db_xref="InterPro:IPR005645"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="PFAM:PF03959"
                     /locus_tag="ATCC64974_90340"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_90340-T1"
                     /transl_table=1
                     /translation="MKILCLHGYGTGPNILRYQLSGLMRDADPSWEFHFLSAEVECPPA
                     PDIGSTFPPPYYCWTRSFDAGSIDAAHALIEEAIDEHGPFDGVLGFSQGAAISVSFLLE
                     HKTAYPDEPPPFRFAIFYSPTIPCAADEAYCRSVLGTLSSADQQSLRSGKDKEIAQLPE
                     PVRSVTESLVKVIKGTHSITRESVPFFLDRPLELIPCALHPNVVPTRISIPSLHLRGKN
                     DVPGLDDCGLLVECLCDSNTRRPIIHSAGHDIPRSGPELKQMLSAVEWVVAKSQLPLL"
     mRNA            complement(join(17693..18699,18753..18864))
                     /locus_tag="ATCC64974_90350"
                     /product="hypothetical protein"
     gene            complement(17693..18864)
                     /locus_tag="ATCC64974_90350"
     CDS             complement(join(17693..18699,18753..18864))
                     /NRPS_PKS="Domain: PKS_ER (20-233). E-value: 8.6e-13.
                     Score: 39.7. Matches aSDomain:
                     nrpspksdomains_ATCC64974_90350_PKS_ER.1"
                     /NRPS_PKS="type: other"
                     /codon_start=1
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="InterPro:IPR020843"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF00107"
                     /db_xref="PFAM:PF08240"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 153.4; E-value: 1.4e-46)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC64974_90350"
                     /note="EggNog:ENOG41; GO_function: GO:0016491 -
                     oxidoreductase activity [Evidence IEA]; GO_process:
                     GO:0055114 - oxidation-reduction process [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_90350-T1"
                     /transl_table=1
                     /translation="MGVQRAVIVRERGQVTLADDVPIPALPDDYILVKTQAVALNPTDW
                     KHVDFDSCAGTVVGCDYAGVVEAIGPRVTKPWKKGDRVAGFVHGCNVMQPQGGAFAQYV
                     IAKGDIQFRVPEWMDIDRAACLGVGMMTIGQNLYQSMQLTDPGMVCDDKITDLQRDEKG
                     NDEDIPSILIYGGATSTGSLAIQFAKLSGLRVVTTCSEVNRAWMHELGADIVLDYHDPH
                     VGDQIREVTDDTLELAFDTISTNQSAAICAAALSSSGGCYNALLDVRCPRGDVDTHVSM
                     AYDMIGEPYLMGGKEVQAQLENLSFGAQWVNAVEILLQTRQIASPRFQVKPGSLAGVTS
                     GLDWLRKGKVRASKLVYIVDETLETARLEIPG"
     aSDomain        complement(join(18113..18699,18753..18804))
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC64974_90350_PKS_ER.1"
                     /evalue="8.60E-13"
                     /label="ATCC64974_90350_PKS_ER.1"
                     /locus_tag="ATCC64974_90350"
                     /score="39.7"
                     /tool="antismash"
                     /translation="VPIPALPDDYILVKTQAVALNPTDWKHVDFDSCAGTVVGCDYAGV
                     VEAIGPRVTKPWKKGDRVAGFVHGCNVMQPQGGAFAQYVIAKGDIQFRVPEWMDIDRAA
                     CLGVGMMTIGQNLYQSMQLTDPGMVCDDKITDLQRDEKGNDEDIPSILIYGGATSTGSL
                     AIQFAKLSGLRVVTTCSEVNRAWMHELGADIVLDYHDPHVGDQIREVTDDT"
     CDS_motif       complement(18248..18304)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90350_0003"
                     /evalue="6.20E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="ATCC64974_90350"
                     /score="9.4"
                     /tool="antismash"
                     /translation="SILIYGGATSTGSLAIQFAK"
     CDS_motif       complement(18413..18445)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90350_0002"
                     /evalue="9.80E+00"
                     /label="PKSI-ER_m5"
                     /locus_tag="ATCC64974_90350"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="AACLGVGMMTIG"
     CDS_motif       complement(18602..18655)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90350_0001"
                     /evalue="2.80E-02"
                     /label="PKSI-ER_m2"
                     /locus_tag="ATCC64974_90350"
                     /score="7.7"
                     /tool="antismash"
                     /translation="CAGTVVGCDYAGVVEAIGP"
     mRNA            join(19431..19631,19699..19843,19899..20167,20217..20579,
                     20631..21573,21632..25956,26010..26682,26744..26892)
                     /locus_tag="ATCC64974_90360"
                     /product="hypothetical protein"
     gene            19431..26892
                     /locus_tag="ATCC64974_90360"
     CDS             join(19431..19631,19699..19843,19899..20167,20217..20579,
                     20631..21573,21632..25956,26010..26682,26744..26892)
                     /NRPS_PKS="Domain: PKS_KS (13-438). E-value: 1.9e-169.
                     Score: 555.8. Matches aSDomain:
                     nrpspksdomains_ATCC64974_90360_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (546-860). E-value: 2.4e-97.
                     Score: 317.5. Matches aSDomain:
                     nrpspksdomains_ATCC64974_90360_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (938-1118). E-value: 1e-25.
                     Score: 82.7. Matches aSDomain:
                     nrpspksdomains_ATCC64974_90360_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1658-1956). E-value: 2.8e-30.
                     Score: 97.2. Matches aSDomain:
                     nrpspksdomains_ATCC64974_90360_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (1990-2166). E-value: 4.3e-55.
                     Score: 178.1. Matches aSDomain:
                     nrpspksdomains_ATCC64974_90360_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (2284-2346). E-value: 1e-07. Score:
                     23.9. Matches aSDomain:
                     nrpspksdomains_ATCC64974_90360_ACP.1"
                     /NRPS_PKS="type: Type I Iterative PKS"
                     /codon_start=1
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013968"
                     /db_xref="InterPro:IPR014030"
                     /db_xref="InterPro:IPR014031"
                     /db_xref="InterPro:IPR014043"
                     /db_xref="InterPro:IPR016035"
                     /db_xref="InterPro:IPR016036"
                     /db_xref="InterPro:IPR016039"
                     /db_xref="InterPro:IPR018201"
                     /db_xref="InterPro:IPR020801"
                     /db_xref="InterPro:IPR020806"
                     /db_xref="InterPro:IPR020807"
                     /db_xref="InterPro:IPR020841"
                     /db_xref="InterPro:IPR020843"
                     /db_xref="InterPro:IPR032821"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="InterPro:IPR036736"
                     /db_xref="InterPro:IPR042104"
                     /db_xref="PFAM:PF00106"
                     /db_xref="PFAM:PF00109"
                     /db_xref="PFAM:PF00550"
                     /db_xref="PFAM:PF00698"
                     /db_xref="PFAM:PF02801"
                     /db_xref="PFAM:PF08659"
                     /db_xref="PFAM:PF13561"
                     /db_xref="PFAM:PF14765"
                     /db_xref="PFAM:PF16197"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 175.7; E-value: 2.9e-53)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ATCC64974_90360"
                     /note="EggNog:ENOG41; GO_function: GO:0016491 -
                     oxidoreductase activity [Evidence IEA]; GO_function:
                     GO:0031177 - phosphopantetheine binding [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]; GO_function: GO:0003824 - catalytic activity
                     [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_90360-T1"
                     /sec_met_domain="PP-binding (E-value: 2e-06, bitscore:
                     24.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4.5e-96, bitscore: 317.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 2.7e-170, bitscore:
                     562.5, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.8e-47, bitscore:
                     157.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MEEHVRDTSGPEPIAIIGMGCRFAGEASSVEGFWDMLRLGRREHG
                     RVPASRYQASAWEHPSHERKGAINHDSGFFLAEDPSHFDAPFFSITSKEAAGMDPVQRI
                     LLEVAYEAFENGGVPMETLPGSATGVYSGCMTNDYELLSTRDIMDMPHNSATGNGKTML
                     ANRLSWFFDLRGPSIMMDTACSSSLTALHLATQALRAGECSQALVTGASLILHPNFTQR
                     LSYMHMLSADGISHSFDSKANGYGRGEGFGAILLKPLSKAMADGDMIRAIVRATGSNQD
                     GRTPGITMPNATAQADLIRSTYSRAGLSMGETSYFEAHGTGTAIGDPTELSAIGASFGA
                     ERKPGDEPLCVGSVKSNLGHTEGAAGVASIIKVVLCLEKGMLVPNAGFSNLNPKIRLEE
                     WGLRLSNSTTPWPSHLLQRASINSFGFGGANAHAILESTAQYLGKTQAPSDSTIEGTPQ
                     VVVVSTHDQSGLDRTADKWTSFLNPCVDGKRKDIALLDVAHTMATRRSQLPFRSFAVVN
                     SLAELRNVMAAGLPTFSRASRKNQAHLAFIFTGQGAQWPRMGVQLLANPVFAASMERSQ
                     QVLQSLDCSWDLLEEIRAGATTSRINRPDRSQPSCCALQVALVDMLRSWGVTPKAVVGH
                     SSGEVGAAYAAGYLTHEDAIRITYFRGVLSQRIAESESRGGMLAAGISAADAQEYLQTL
                     PPESAVVACVNSPSSVTLSGNIEEINLLEKRLQADGCFARKLRVDTAYHSPHMRALADD
                     YKTAIESIQPVDKYNGSISMFSSVTKELLQAADLDASYWVRNLVSPVEFAAAVTKVATM
                     TEAGRGRGRRRVVPVKWAGFLEIGPHEALKGPFNQTLQEANADLASTPYKSLVLRKQDS
                     RQTALQVAGLLWCLGYAINLDTANQSFLESRRPQVSRDLPSYAWNHQSTFWHEPLESAR
                     LRQRKEPRHDLLGMPWDYQNELEPRWRNFLRVSELPWLADHVVAGSIVYPAAGMVSMVA
                     EAARQLAGTTKWLEGIEFNDLDFFRGVVIPPDERGLEIVLHVAPHHGMNGWYEFGIFSL
                     PENSSWVQHAKGAFAPQYADEDGVGCAADWQCTVQRVRQTQAMAKKAEIEAVYEWLSET
                     GGVTLGPTFRSMAGVAFDSESRLYVTGVAPNTKQTMPYERESPCLVHPTSLDSLFQAAV
                     VSCSDALSNHNANIPVGVERLYLSTAFSLQPGDRFDVHVETRYENGVSFTESIASDPSW
                     QQPGMVLQGVRLGRVPTRSGGSTIEEIQQSRFSTLHWAEHVDSSGGLEGRCSGGLQNWL
                     GRVCHTHGDARVLVVTTKDIGQVVEALRDYAPKRSHRPRLQKLTIVLSDPDTEALTNQV
                     KIIKDSLDGCQVLPVASLQDIGTDLLGETAYDAIIVDHPDVWSGDNTKAFFNSLLSITR
                     PDSWIAARATAENHDAAIRNAGHADWEVQGSIEQPGYLLIRRQLAPVELDPTIYILSSA
                     AAESVGPLLYELDGVVNKLGSKIELVDVDKAPDLKEKMIISLLELDRPWTVNWTPDEIS
                     RFQSLLQAKCLLWISQCPGHEASGYAGFGATTGLLRTVRNENPHIVLPQLLVSGKDKDP
                     HNLARSIAHVLQLTLKPRSRPHDLEFYMQDNRLLVPRAITARAVDESMDALLRGPRPTL
                     AELAQDSRPLRLCTKSQDISDARWELDERLNSALPDDLVEVQLHKVSISELASKSGISP
                     EARIAAIEAVGIVRQVGMSIGSAFQVGDEVLCAIPSDAWPSALTTHVRLPASAIWNSPS
                     QQSETQSVSMPVAFAAAYTSLFGSSGASASSVLIVGSVSQTLRATVDCALAAGMQVYVA
                     VDGEDGINGMRSKYVGLHERIIPIHRELDTTVKRLTGGKGVELSVCCLGGSVSRLAARC
                     LAYSGRLVDLSEELNLAALPQTFVDRGCTVSSVRLSRMLREAPRQLQANFHRAVDLLGS
                     DALASVQAYQSFPVSQVADAVAHARDSGTRAIVDLQAPGQVPIVPALPDPAPLPAENTY
                     ILVGGLGTLGIALASTLVDCGARHLVFLSRSGAVRETQQTALKELQDRGARTDVVRCDA
                     ACQEDVKSLLTRAENNRWRVRGIVQCATVLKDGMFEHMDFDAWKQSTEPKVQGTWNLHK
                     AFYSTPLDFFVTLSSIASITGNMGQANYAAGNGYMDALMIWRRKHHLPGHSINIGLVPD
                     ASGVSDVAETPEQRRQRYRHLEGTEILQREVQTLLRVIVQKITRVPAQVIAGLTDTLPR
                     TDGAASWQFDRKFDHRIQVVADEDAAAGVVKTSTLLKKAQSVDEAVRVVNQALQEYLAR
                     AMASSAEAIDLELPFSALGVDSLKAAEVQNWVSREMGAELSSFEFIGAQPVRVLAEKIA
                     TLSSFVVAT"
     aSDomain        join(19470..19631,19699..19843,19899..20167,20217..20579,
                     20631..20966)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC64974_90360_PKS_KS.1"
                     /evalue="1.90E-169"
                     /label="ATCC64974_90360_PKS_KS.1"
                     /locus_tag="ATCC64974_90360"
                     /score="555.8"
                     /tool="antismash"
                     /translation="IAIIGMGCRFAGEASSVEGFWDMLRLGRREHGRVPASRYQASAWE
                     HPSHERKGAINHDSGFFLAEDPSHFDAPFFSITSKEAAGMDPVQRILLEVAYEAFENGG
                     VPMETLPGSATGVYSGCMTNDYELLSTRDIMDMPHNSATGNGKTMLANRLSWFFDLRGP
                     SIMMDTACSSSLTALHLATQALRAGECSQALVTGASLILHPNFTQRLSYMHMLSADGIS
                     HSFDSKANGYGRGEGFGAILLKPLSKAMADGDMIRAIVRATGSNQDGRTPGITMPNATA
                     QADLIRSTYSRAGLSMGETSYFEAHGTGTAIGDPTELSAIGASFGAERKPGDEPLCVGS
                     VKSNLGHTEGAAGVASIIKVVLCLEKGMLVPNAGFSNLNPKIRLEEWGLRLSNSTTPWP
                     SHLLQRASINSFGFGGANAHAILESTA"
     CDS_motif       20075..20122
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90360_0001"
                     /evalue="1.60E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="ATCC64974_90360"
                     /score="17.1"
                     /tool="antismash"
                     /translation="GPSIMMDTACSSSLTAL"
     CDS_motif       20313..20351
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90360_0002"
                     /evalue="9.60E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="ATCC64974_90360"
                     /score="12.3"
                     /tool="antismash"
                     /translation="FDSKANGYGRGEGF"
     CDS_motif       join(20544..20579,20631..20642)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90360_0003"
                     /evalue="7.50E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ATCC64974_90360"
                     /score="11.9"
                     /tool="antismash"
                     /translation="YFEAHGTGTAIGDPTEL"
     CDS_motif       20706..20750
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90360_0004"
                     /evalue="2.00E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="ATCC64974_90360"
                     /score="10.8"
                     /tool="antismash"
                     /translation="GSVKSNLGHTEGAAGV"
     CDS_motif       21288..21341
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90360_0005"
                     /evalue="6.90E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ATCC64974_90360"
                     /score="18.4"
                     /tool="antismash"
                     /translation="FIFTGQGAQWPRMGVQLLA"
     aSDomain        join(21291..21573,21632..22290)
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC64974_90360_PKS_AT.1"
                     /evalue="2.40E-97"
                     /label="ATCC64974_90360_PKS_AT.1"
                     /locus_tag="ATCC64974_90360"
                     /score="317.5"
                     /specificity="Minowa: mmal"
                     /specificity="consensus: pk"
                     /specificity="PKS signature: Malonyl-CoA"
                     /tool="antismash"
                     /translation="IFTGQGAQWPRMGVQLLANPVFAASMERSQQVLQSLDCSWDLLEE
                     IRAGATTSRINRPDRSQPSCCALQVALVDMLRSWGVTPKAVVGHSSGEVGAAYAAGYLT
                     HEDAIRITYFRGVLSQRIAESESRGGMLAAGISAADAQEYLQTLPPESAVVACVNSPSS
                     VTLSGNIEEINLLEKRLQADGCFARKLRVDTAYHSPHMRALADDYKTAIESIQPVDKYN
                     GSISMFSSVTKELLQAADLDASYWVRNLVSPVEFAAAVTKVATMTEAGRGRGRRRVVPV
                     KWAGFLEIGPHEALKGPFNQTLQEANADLASTPY"
     CDS_motif       join(21528..21573,21632..21702)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90360_0006"
                     /evalue="3.70E-13"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ATCC64974_90360"
                     /score="41.5"
                     /tool="antismash"
                     /translation="GVTPKAVVGHSSGEVGAAYAAGYLTHEDAIRITYFRGVLS"
     CDS_motif       22069..22116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90360_0007"
                     /evalue="2.00E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="ATCC64974_90360"
                     /score="13.7"
                     /tool="antismash"
                     /translation="LDASYWVRNLVSPVEFA"
     aSDomain        22525..23064
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC64974_90360_PKS_DH.1"
                     /evalue="1.00E-25"
                     /label="ATCC64974_90360_PKS_DH.1"
                     /locus_tag="ATCC64974_90360"
                     /score="82.7"
                     /tool="antismash"
                     /translation="HDLLGMPWDYQNELEPRWRNFLRVSELPWLADHVVAGSIVYPAAG
                     MVSMVAEAARQLAGTTKWLEGIEFNDLDFFRGVVIPPDERGLEIVLHVAPHHGMNGWYE
                     FGIFSLPENSSWVQHAKGAFAPQYADEDGVGCAADWQCTVQRVRQTQAMAKKAEIEAVY
                     EWLSETGGVTLGPTFRSM"
     CDS_motif       22609..22686
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90360_0008"
                     /evalue="2.20E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="ATCC64974_90360"
                     /score="33.0"
                     /tool="antismash"
                     /translation="WLADHVVAGSIVYPAAGMVSMVAEAAR"
     aSDomain        24685..25578
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC64974_90360_PKS_ER.1"
                     /evalue="2.80E-30"
                     /label="ATCC64974_90360_PKS_ER.1"
                     /locus_tag="ATCC64974_90360"
                     /score="97.2"
                     /tool="antismash"
                     /translation="DARWELDERLNSALPDDLVEVQLHKVSISELASKSGISPEARIAA
                     IEAVGIVRQVGMSIGSAFQVGDEVLCAIPSDAWPSALTTHVRLPASAIWNSPSQQSETQ
                     SVSMPVAFAAAYTSLFGSSGASASSVLIVGSVSQTLRATVDCALAAGMQVYVAVDGEDG
                     INGMRSKYVGLHERIIPIHRELDTTVKRLTGGKGVELSVCCLGGSVSRLAARCLAYSGR
                     LVDLSEELNLAALPQTFVDRGCTVSSVRLSRMLREAPRQLQANFHRAVDLLGSDALASV
                     QAYQSFPVSQVADAVAHA"
     CDS_motif       25681..25779
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90360_0009"
                     /evalue="6.20E-13"
                     /label="PKSI-KR_m1"
                     /locus_tag="ATCC64974_90360"
                     /score="41.3"
                     /tool="antismash"
                     /translation="TYILVGGLGTLGIALASTLVDCGARHLVFLSRSG"
     aSDomain        join(25681..25956,26010..26261)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC64974_90360_PKS_KR.1"
                     /evalue="4.30E-55"
                     /label="ATCC64974_90360_PKS_KR.1"
                     /locus_tag="ATCC64974_90360"
                     /score="178.1"
                     /specificity="KR stereochemistry: (unknown)"
                     /specificity="KR activity: active"
                     /tool="antismash"
                     /translation="TYILVGGLGTLGIALASTLVDCGARHLVFLSRSGAVRETQQTALK
                     ELQDRGARTDVVRCDAACQEDVKSLLTRAENNRWRVRGIVQCATVLKDGMFEHMDFDAW
                     KQSTEPKVQGTWNLHKAFYSTPLDFFVTLSSIASITGNMGQANYAAGNGYMDALMIWRR
                     KHHLPGHSINIGLV"
     CDS_motif       26061..26090
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90360_0010"
                     /evalue="5.40E-04"
                     /label="PKSI-KR_m3"
                     /locus_tag="ATCC64974_90360"
                     /score="13.2"
                     /tool="antismash"
                     /translation="PKVQGTWNLHK"
     CDS_motif       26112..26222
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ATCC64974_90360_0011"
                     /evalue="5.70E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="ATCC64974_90360"
                     /score="63.9"
                     /tool="antismash"
                     /translation="LDFFVTLSSIASITGNMGQANYAAGNGYMDALMIWRRK"
     aSDomain        join(26616..26682,26744..26862)
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ATCC64974_90360_ACP.1"
                     /evalue="1.00E-07"
                     /label="ATCC64974_90360_ACP.1"
                     /locus_tag="ATCC64974_90360"
                     /score="23.9"
                     /tool="antismash"
                     /translation="LARAMASSAEAIDLELPFSALGVDSLKAAEVQNWVSREMGAELSS
                     FEFIGAQPVRVLAEKIAT"
     mRNA            complement(join(27030..27238,27334..27485,27555..27755,
                     27834..28051))
                     /locus_tag="ATCC64974_90370"
                     /product="hypothetical protein"
     gene            complement(27030..28051)
                     /locus_tag="ATCC64974_90370"
     CDS             complement(join(27030..27238,27334..27485,27555..27755,
                     27834..28051))
                     /codon_start=1
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="InterPro:IPR036291"
                     /db_xref="PFAM:PF00106"
                     /db_xref="PFAM:PF08659"
                     /db_xref="PFAM:PF13561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     132.1; E-value: 4.1e-40)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC64974_90370"
                     /note="EggNog:ENOG41; GO_function: GO:0016491 -
                     oxidoreductase activity [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_90370-T1"
                     /transl_table=1
                     /translation="MSFPYKHILVLGATAGIGRALASRFVQSEVKVTVVGRRKERLDEF
                     LQEHGEDKANAVQFDISDLDKIPGFAAEIMTTYPTIDSVFMNAGIMLPTDMTDPEKFDL
                     PSFYKQMHVNFTSYVALTHAFLPYLTKEGGHTSLIYTTSNLSIVPATWMPAYSASKAAL
                     NAFILCLRDQLRKSSVKIIEVSPPAVQSELHDYMGEEGRKVGMPLKEFTAEAFQGLLDG
                     KDQIVVGSLGPAEVFLDIVNKRRAATTQLAKMMRGEK"
     mRNA            join(28956..29225,29281..30747)
                     /locus_tag="ATCC64974_90380"
                     /product="hypothetical protein"
     gene            28956..30747
                     /locus_tag="ATCC64974_90380"
     CDS             join(28956..29225,29281..30747)
                     /codon_start=1
                     /locus_tag="ATCC64974_90380"
                     /note="EggNog:ENOG41"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_90380-T1"
                     /transl_table=1
                     /translation="MDSAFPKRPSFVRYGPYTYDDYGVTVANIPRASSQTLATLFPTNP
                     VTAPSRRPVKRWIAAQLQHFGIPYQPSNTIAQLLALLEREYKDGKCSYESPSVRLLDKT
                     MYEMYNAVQEAYQQQKAEWRKKKFARQVSPSDEALFDPFLFMAKYFLDKENGVPDKTKQ
                     TEAIVLHNVYNQQFVSTALSIPGLSFHISHPATVIGWADTFEEGLDAGFASLSQNHVKE
                     YVPTFEANFDHCRFLTKYFLSLDYPYEMGVPARDRTVEPVQLMPQLYFDVREKLRKEVA
                     NINGLLIATTPGRGGTWTLITWSEYADKLTGVVSKIHAASMNEKMYDDTLISLVWQSKL
                     SRHTLFKQCVKPNNNTSALRLSQLQGQYVIRCNAIDPWGYEDFSLDINAPRRNDPAARA
                     TFSLGKLQGAMILALDCDKVDQMRKILEKKSTATQHSNPESDDDNEMDEHLTVHRFRDD
                     DAKWRVYLQYAGTCNGLNQVDEHNEQVGFIDFNVDPERSDDDEKALGYGLAYGRGLIVG
                     PKYMTSRKSDKGEILEIEVFKWTSDTVRVAAEWNAFNFWGGFEARFRVGERAMTMTKGY
                     EL"
     mRNA            complement(join(31661..32256,32306..32512,32559..33173,
                     33223..33343,33392..33490,33555..33630,33695..33729,
                     33812..33861,33943..33982))
                     /gene="HSE1"
                     /locus_tag="ATCC64974_90390"
                     /product="ESCRT-0 subunit protein hse1"
     gene            complement(31661..33982)
                     /gene="HSE1"
                     /locus_tag="ATCC64974_90390"
     CDS             complement(join(31661..32256,32306..32512,32559..33173,
                     33223..33343,33392..33490,33555..33630,33695..33729,
                     33812..33861,33943..33982))
                     /codon_start=1
                     /db_xref="InterPro:IPR001452"
                     /db_xref="InterPro:IPR002014"
                     /db_xref="InterPro:IPR004152"
                     /db_xref="InterPro:IPR008942"
                     /db_xref="InterPro:IPR036028"
                     /db_xref="PFAM:PF00018"
                     /db_xref="PFAM:PF00790"
                     /db_xref="PFAM:PF03127"
                     /db_xref="PFAM:PF07653"
                     /db_xref="PFAM:PF14604"
                     /gene="HSE1"
                     /locus_tag="ATCC64974_90390"
                     /note="GO_function: GO:0005515 - protein binding [Evidence
                     IEA]; GO_process: GO:0006886 - intracellular protein
                     transport [Evidence IEA]"
                     /product="ESCRT-0 subunit protein hse1"
                     /protein_id="ncbi_ATCC64974_90390-T1"
                     /transl_table=1
                     /translation="MFRAQQNAFDDAVAKATDENLTSENWEYILDVCDKVGAEESGAKD
                     AVAAMIKRLAHRNANVQLYTLELANALAQNCGPKIHRELASRSFTDALLRLANDRNTHQ
                     QVKSKILERMQEWTEMFASNPDFGIMEQAYMKLKTQNPNLQPPSKPGKREITDADRQKE
                     EEELQMALALSIREKATIAPAPQPEASSSAAPVNQTQAPAATSQAVPSGTSAATVSRVR
                     ALFDFQPSEPGELQFRKGDVIAVLESVYKDWWKGSLRGQTGIFPLNYVEKLPDPTVEEL
                     QREAQMEADVFGQIKNVEKLLTLLSTRSSELNVQDNEEITALYHSTLAIRPKLIELIGK
                     YSQKKDEFTQLNEKFIKARRDYESLLEASMAHPAQSQYGRPAQPPYGYPGAAPVGYPQG
                     PPQADPQRYFSPRPQAETQAPPANAPAFYGTEQAHAYPPTSQSPDPRQTPPAGAPYQQQ
                     QPQQQRQPSSESYQPVYHRPESTYENPQELGTSVYDSPVEHPASQRPPYPGAVQVPAAV
                     QQHFQQQQQQPQQQSQQPHPEYPASGYTPEDASRPPAHQAQPPYPSHQPPPMHQPPPVP
                     GTSTTPTPYPALNAGGGYQAYNPSQTDVSNPASFYR"
     mRNA            complement(join(35420..35524,35579..35913,35966..36065,
                     36122..38098))
                     /gene="STE20"
                     /locus_tag="ATCC64974_90400"
                     /product="signal transducing kinase of the PAK"
     gene            complement(35420..38098)
                     /gene="STE20"
                     /locus_tag="ATCC64974_90400"
     CDS             complement(join(35420..35524,35579..35913,35966..36065,
                     36122..38098))
                     /codon_start=1
                     /db_xref="InterPro:IPR000095"
                     /db_xref="InterPro:IPR000719"
                     /db_xref="InterPro:IPR008271"
                     /db_xref="InterPro:IPR011009"
                     /db_xref="InterPro:IPR017441"
                     /db_xref="InterPro:IPR033923"
                     /db_xref="InterPro:IPR036936"
                     /db_xref="PFAM:PF00069"
                     /db_xref="PFAM:PF00786"
                     /db_xref="PFAM:PF07714"
                     /db_xref="PFAM:PF14531"
                     /gene="STE20"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 177.7;
                     E-value: 5.4e-54)"
                     /gene_kind="regulatory"
                     /locus_tag="ATCC64974_90400"
                     /note="GO_function: GO:0005524 - ATP binding [Evidence
                     IEA]; GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA]; GO_function: GO:0004674 - protein
                     serine/threonine kinase activity [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /product="signal transducing kinase of the PAK"
                     /protein_id="ncbi_ATCC64974_90400-T1"
                     /sec_met_domain="Pkinase (E-value: 2.8e-72, bitscore:
                     239.0, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MNHDSFSSLKFRRSSSKLHKDPPSFSSRILKSQQSNTSLKRHPSA
                     PVYPRSSTGGSREHSRTRSNAYGSSSSSLEQNSGGPSPVLAGNQPGYFSNTSNPSKSRP
                     PHSGRFSLTEQSSDELIGPPFDSRGMLSSLQENTTETVPQKPPNLRSATSPDSRGLRQS
                     ASFTALQNRMETFVHRTTDNDRPANPKRLSDEGGGGVGSRPFGTGRSKKSSFSSFVNSM
                     LGSPRGIKISAPENPVHVTHVGYDNQTGQFTGLPKEWQRLLQENGISKKEQEEHPQTMV
                     DIMRFYEKNAQGDDEVWHKFDHAYPQPQSVSSPISGGQTNAVGAGSYGPTSARTSPPTS
                     PRFPQNHEGSFENPRAPPPIPRGPSAATPAVGGFVPNRAPPKPPTPANITPSRPAPQPP
                     TAGSYSAAPARPPQEAYSPPQFDTPPIPETEPLQSEPKPQLSRSNSRANGTPVPWQSHN
                     VPTPAQYQQKQEQAMAAAQQAIATIQLDRSRSQRQQQPTRQEQKQPSVQSPPHHVSPVD
                     EAARAAPAARPRQRPRQSNAMDIRSRLLAICTPGDPTRLYHHLNKIGQGASGGVFTAYE
                     NNTNKCVAIKQMNLDLQPKKDLIINEILVMKDSKHKNIVNFLDSYLHGLDLWVVMEYME
                     GGSLTDVVTFNIMSEGQIAAVCRETLSGLQHLHSKGVIHRDIKSDNILLSMEGNIKLTD
                     FGFCAQINDSHNKRNTMVGTPYWMAPEVVTRKEYGRKVDIWSLGIMAIEMIEGEPPYLT
                     ESPLRALYLIATNGTPTIKDEHNLSPVFRDFLHLALKVDPEKRASAHDLLKHPFMSLCA
                     PLNHLSPLVKAARASRAQEKAQKGGA"
     mRNA            complement(join(43429..43922,43976..44657,44754..45098))
                     /locus_tag="ATCC64974_90410"
                     /product="hypothetical protein"
     gene            complement(43429..45098)
                     /locus_tag="ATCC64974_90410"
     CDS             complement(join(43429..43922,43976..44657,44754..45098))
                     /codon_start=1
                     /db_xref="InterPro:IPR001248"
                     /db_xref="InterPro:IPR026030"
                     /db_xref="InterPro:IPR038271"
                     /db_xref="PFAM:PF02133"
                     /locus_tag="ATCC64974_90410"
                     /note="EggNog:ENOG41; GO_component: GO:0016021 - integral
                     component of membrane [Evidence IEA]; GO_component:
                     GO:0016020 - membrane [Evidence IEA]; GO_function:
                     GO:0022857 - transmembrane transporter activity [Evidence
                     IEA]; GO_process: GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /product="hypothetical protein"
                     /protein_id="ncbi_ATCC64974_90410-T1"
                     /transl_table=1
                     /translation="MDFKTLEDGNPIEPKQATASVEEHALVKPSGFFARIRYYEELLDR
                     KMGVESHSLDRVLPEERKPPNTLAMAFIWASATMNLSCFSTGFMGKEFGLTLGQTIAIM
                     ICATFLGAALTGWCATMGPGTGLRQVAISRYSFGFYPSSIIAALNVVEQLGWASVSCIT
                     GGQALRAVSDNHISMVVGVVIVACVSLCFSFFGLRAVMTIEQYIWMVSFVVFIIVYGES
                     AHHASLSDPGTVSGLTKSGNVLSLISVIYGSSASWCSIVSDFYVHYPVNTSKVKVFIYT
                     TLGISLPTCIGMLLGACIASALDGNPEWAAAYDQGTGEILQTIIYPRKFAKFLLVLLVL
                     CGIGMNCIAIYAGSLSAQLFAKPFQKIPRIIWTLLVFACILVIGIAGRDHLLTVLDNFL
                     SLLGYWNTSFFVILFCEHYFFRNGNLANYDLDAWNTPSKLPVGYAGLTAFLCGAAGWIV
                     GMDETYYVGALARKIGTDGGDIANELAFVFTSLSYIPLRKLELKYVGR"
ORIGIN
        1 tcacttcagg ggacttccac tgaagaagtc acccgttcca gggccagcaa agctgccgtt
       61 gctgggcgtc agagcgatgg agcgtcggaa cgcctgtctg ggagtggctg gggcactagc
      121 agcggcgccg gcaacatcag aagtgctggg agtattgcga ccgctgttgt tctgcatcgt
      181 aaccgccgtt ccggggcggg agagcacggt tgggacaccg ttcctgggag ggggtcggaa
      241 tccaagctta gagccttcgc ggaagatctc ctccaatatt tgagacacaa tgcctgcatc
      301 ttcgtattct ttaaatttct tccatagacg cagtgccatg cgtgcgtctt caatggagtc
      361 gtgtccttgg ctgtcatcgg ccggttcctc ttggatgtat tccttgaaca ccgcccaggc
      421 cagataacga aggctcagac ggcgattctt cccggggtgg aagaataagt attgggtgtc
      481 cacggtctgg cttttgggga cttgaatgtt aaccttgcgg aaatcagagg ctaagccgtg
      541 tccgacaaac acgcagccta agttgaggag cagccagagc ttcttgtatg ccaccttcag
      601 cgggacaagg ttatgctggc taacccttgg gtccaggtcc ccgggcttaa tccctgagta
      661 ctgagtgacg taatcgacga tattctcttt tatggtgata tagtcgtcta tgaagggaac
      721 accttctcgg atccctgagc ctctgagaac agacacccta gcaagaccgc tcttactggg
      781 gcgtacaatt tcctgagagc catccgcttt cacatcgatt tctgctttct caagatctac
      841 aaactcggta tcgagagcaa caggcgtacc gggggtgggc ttctcctctt cggagagcgt
      901 gacgcgagac tctaccggac ggccaccact gagaaaggga aggttagcgc gaagcacttg
      961 ctactagaag gagctcaact tactttagcg accagtcacg gaagagaaga gtggtgtcga
     1021 gcgcgtcttt ccaagtatca tccatagcat gtcgaccgtc ttgcacctgg taggctagca
     1081 cgcacggtat cttccatggt tgattgaagc ggagggcttc ttctttgtcg acttccgtaa
     1141 cgaggaagtc gttgaaaaga tgccacttgt tcttggcttc cggttcacga gatgagatgg
     1201 atacgtttat gaaagagact agatgtgcct tttggtgctc tggaatatcg atctcacaaa
     1261 ccaaacctac caggtcatat accaccagac cgggcatctt agcttggact cgaagtttca
     1321 agtcttcacc ttcgaagcat aggatctgac caccttcgat gacgattcca acttcttccg
     1381 gcaaccaccc aggaattgcc caaagccgcc ggcagatggg gttggtgaga gccgcattaa
     1441 gcatcaggac ctgaggcatg cggtgaactg atttccgaat agcaacttgc tgatatcgac
     1501 gacagtagtt gcaccatcct ctgttttgcg cttctcgctc aatgctggct cgtaagatat
     1561 ttgagaaccg gaaggcagga ttcctgcgag cttgcttgat atcgatcgca ggatagttca
     1621 gctcgttgac aagagagttt cccggtctca caatctcgtt ctggcagaac atgcagcgaa
     1681 tggactcgga tgcgaccgtt gctagtctgt ggtccaggtc gtccgagctc ggcgaaatca
     1741 tacggaagtc gtgcgaaatc tgacccagga aaaatctgtt gacagcttga atcgcagccg
     1801 aaagtgactt atttgtcaag ttttcttcaa aaagacctag gttggatgct tcgcgataac
     1861 tgctgaaggt cttcagtagg ttcgttgctt ggcagttttg gccactcgct ttttcgagca
     1921 tatcgaacag gtagcccatc tcgcagagca gacatgtctc gaaaatacaa gaacttgcgg
     1981 catggtggag agctacgttg cgtatataag ggatgaattt gaaaagttga aggagagcgt
     2041 tcgtgaagga atttgcaata tgtgtttcca aaccagagaa cgttgtctga ttgtagaacc
     2101 tattcaaagc ataagttgct gtgtatcatt ccacggaata cgagaaaact tacctaaaat
     2161 cgaagtcatc gacaccaaac ctactgtact tgatctcaac attgctgtat ttgaggagag
     2221 gatcatcgtc cgtttctcca ttgattttgg cacccgccag agcctcggca gcgtcactta
     2281 tagccccctc tgattttgcc ttattctgct ctcgtgcctt ttcactcaaa aacttgggag
     2341 caataagagc aggctcagca gaagccagag cgcgagtgtt ctccacctga taacgccgtg
     2401 tcttcttcgg attcggcgca tggtgaccga gctctgccgg acggagataa gggatcagag
     2461 cctgatctac ttgaggaggg ggactgccga cttcaaaaac cagatgactc ggccacgcag
     2521 agaaaagacg ctcgtgataa taaggcatgc caatcatact tagaggcgtt tctggagacc
     2581 aatccagggt agggggacga ggagctacat cgccgaattc tgcttctttg ctcatctcat
     2641 tgaaatgaac ctttgctggc gatccccata gatggatggc acattcggca tcattaatgg
     2701 ctaatgcttc tccggatggt gacaggtcga taccgagcat gaaggaaacg ttcgcctggc
     2761 gaaggttgat ggcattcgga ttcatcaggt ccacaacctg aagctggcct gtctgagatg
     2821 caacaaaact cgttgtatgc aacttcgggt gcatccgtac ataggcagct ccggcgtgaa
     2881 agggtatcgg gggtaacggc gaaagggtct tcaggtcgta cacgttggcc aacggatcga
     2941 cgatggggga acccagatgc ctgacagaga agccgcaggt aaccaaaaga tcattccgag
     3001 catccatatc attaactgca gtcccgtgtg ctttccacga cttcaccaca ctgaagtcgt
     3061 tcaggctcag cgcgttgact gagcccgtat ctgtcgctgc gcaaaggtat cggctcttct
     3121 tcatgattgt gtagttatac tcggtatgca gcttgtctat tataagtccc ttatcaatat
     3181 caattgtaaa catcgatttc tgacatcctg ccactataat ccggttggtt tgggctgtga
     3241 agctcatgca gcggagatcg gtcatttcct catgagcgat gtgccattgt gtcaagccgc
     3301 gccgtgttat catgtgcaca cttttcgggg agagcgagat aacgcctctg tcatggaaaa
     3361 taatctgccg taccggctcc gtcgcaggat gtgcccggac ggaggtatat cgctgaagtt
     3421 cagggccgaa gaacgaggtg attcgtccct aatggagtac acaaacgctg gtcagcacag
     3481 ccttcggtat tagctgcaaa taatggaaaa ccgacaaatt catttcccac ccacaacaac
     3541 tccatcacat catcaaaggc tattgcggtt gcgattgtcg gcagggcatg cacgctcggt
     3601 gcaggcaccg gaatgcgcga cagttcatcc caatcggcct ccatggcctt gacatcgcac
     3661 ccggcaaggg tgacgagctc tagataggga tgagatttgg attatcgcgg agtcaagatg
     3721 attcaggcaa ggcgtagggt cagtccattg ggggtcaggg cgaaagcggg catcgttcgg
     3781 cgaaagcgcg agtgcgggga gaaggtctgg ctggaaaagg cgtggttgtc gaactccgga
     3841 acaccaagca cagggggcaa gattcacaag ctggcaccca cacgaacagt cccaggctct
     3901 cgtttctggg agcaacagca cacgagacaa atggtctctg gggaaggggt accttccagt
     3961 cagagctgcc ggcaatggct gatgaggtac cgacgcatat tttcacgtga cttcagcccg
     4021 agcgggacaa acatccagca catcacgccg ttgcttcgtc accgcctact gcataaaccc
     4081 tcgtacatat gtatttcttg ctgagttgcg tgattaactg tattcctgac tattctaata
     4141 gggttggtat gttcttaatt actcgtaaac taagttctat cggcttttag gaattcgaca
     4201 actaatagtc aggactatgc tcttgctgca gacaacggag cacctggatg gctagcaact
     4261 tatttatata gccggctcga cgggaagata gactactaaa taatgatact acttgtcatt
     4321 ctgcgttgac tgaagtgtat actaagaata ggttagcaag tggccctcga ccatagcagc
     4381 acgcgaatga ggaaagaagg ttataaagta agaggtgcct tggtattata ttatgatagt
     4441 caccaaaaga tcaggaatta gttggacttt tgtgtaaagg atagagagat taggggccca
     4501 gctggcaggc tgaatcttac aggcgcccat acaagattca tcatccggag ctggggctac
     4561 aggactatct ctgtgtagaa ggagtccgaa taactctcgt ccgcaaggct ctcgagcatg
     4621 ctatatgcgt aggcagggat ccaagcccag cagcccgctt tattatgaaa ctagtcgttc
     4681 atttaccaac tgcaagagct cagggctcta ggagggtatg tagcggatcg ccatgataac
     4741 aaagtgtcca ctgtaccaag ccaacagacc actgtctaca cctctccata tcttcgcatt
     4801 cgaaccacac acccttcccc acaagaaacg accaacgtaa gaacctgcct ctcgtcgccg
     4861 actcctttct ccatcctaca cccctccgcc tgctcaatga cctcgaatgt ctgcagcaac
     4921 cgcataatgg tgtacccgac ctctaacaag gcaaattcgc gtcccagaca gacccttggt
     4981 cccccgttaa atggcaaata cccccagcct acatccttca acgcatcgtt ctcccagcgc
     5041 tcgggtcgaa atttatctgc gtcggcgcca tagatatctc tacgccggtg catcgcgtag
     5101 acgcagtatc ctacggcctc gccttttcgg acgaggatcg gtgccgtgcc tgttggtccg
     5161 ccgcctgtgg ggagggttgt ggttttggtg gcggcgcgcg agtttacagg gacggagggg
     5221 taaaggcgga ggactgggga tttagtgagc atcaggagag tgcgattggt ttgggtaatt
     5281 cgaggttgaa ataccttctt tgatgacgag ggagagatac ggaagtgact tgacttggat
     5341 tatagtaggt gccggcgacc taggtccaat cccgactgta tcactgattt cggcccgcaa
     5401 cttggaaagg acgggaggat gctggacaag tagacgtctt gatttgtttc aagtgtcagc
     5461 ttactcgaaa gaataaacct tggtacatcg gcccttacag agtccaagtg aggcaacaag
     5521 ccgtagtgtc cctcccagct aacaggatat tcaggcactg atcccgaagc acttccgggt
     5581 tccgggtttc ctcgataaag gcatcaatga agatgtacgg ctctgtcttg gtgcccggag
     5641 tcttttttgt agtcaagtcc aaggcctttt gtacagcacg gtccacaaat tcatggcagg
     5701 tcttacacgc ttctcgaaaa tccctcccgt ctagaagcca gtagaagccg cccaatcgtc
     5761 cgcgtttggc caagtactcc tgtccaagat tgaaagcgtt cgcgaagtcc gattcctggt
     5821 ttttgatgcc ctctaattgg agagacggca ggtgttgccc aaacagtaga aagagggtag
     5881 tctcgaacgt gaggcgaaag aaaagcggct gtagattgac ggcgttgtca tcagaaatgc
     5941 tggatatgag attgtctacg gcgctgcgta tttgctcaaa gttggtgaac ctgttcgtca
     6001 tgaactgtgg gcgtagccgc tcgcgtgagt gccgccactg tgcaccatcc tgagtgaaga
     6061 ttccactccc caacaagggg cagaaagttg ggggtcgcag tccgagtcca aaatctgaag
     6121 tttcatttgt cagtggtagc aaaaagatcc ggcgttcaag gtccactgac cagcatattg
     6181 agtcgacaga agagcttgta tgttctgagg gtcgatagtg tcgactcctc gggagaaaag
     6241 gagattttgc tcgaacgttg tgccagactc agcaacgaca ccgagaaaga atttgagaat
     6301 ttgctgccta cggtcatagt gaaatgcttg aacgagtaga tccaagccca gcggccaagt
     6361 agagttccat tgtcttagtg gcaagcatcc atttgcggca gcaactttgt tgtttgcctg
     6421 agatacgagt tagggaacaa tgaatctaat gcggacaggg ttgctggaca acgattcata
     6481 ctcgtagttc tcgcttctgg gcaatgaatc tataggcgag tgcgcatatc catgttccca
     6541 caataaggct gggagccact gagttgagaa atgccatgtc gcttgcatga aagtaatctg
     6601 agtgaaagtg cagtattcca gagaatcacg tactgggtat tcaagctctg aagtactcat
     6661 atatgacctc cccacctact ctgtggttgc atcagtaaga tgactcaggg gtagagcgcg
     6721 tacgcctagg cacttaaggt tgcacaaact gtactagtat gagatgatga ctcctggcag
     6781 cactaccaca agggagagaa gtggggttga tgcttgctag acaggaagtc ccaacatagt
     6841 ttcaccgttc tttatgaaag gccgcggccc gcctgccttg ccattgtgtt tacgcgaaac
     6901 gtcagtggct gattttcaga gtcgagagtg tggtacgcgc ttaaagaact ctcgcgaatg
     6961 tctctgatca cacacattgt ggcaaattac agctgctcaa tatattcgtt cgtacacaga
     7021 cgggctcggg agagccgggc atgagcactg cagagcaggc cgtctgggct aatatcgcag
     7081 cggtagtctc cttccaccgc tttgtgaaag tgagaactaa gaaatctttc ggaatgacgt
     7141 acttgcttct gtagaccaca tccaggcctg tcagggagtt aacgaccaga caatccgggc
     7201 aaatcgaaca cgtcgctggt atgggcttac ccagtggctt ggaccggggt cgaggcttgg
     7261 ccgcgagcaa gcccaacgct ctgcaaattt cagcagtgtg cttgctaagt caggatgctg
     7321 gaaggatgcg gaagtactac agttgcctgt gaaaaattat acgccccgcg tcttgggatt
     7381 tgaccatcct tcaacgcggc ggataatctt ggtgttagca cagacctact ggagtcaagg
     7441 gcatggagac gaggctgcgc aattgcaaca gactgtcttg cgggcttgtg tcgcttcgta
     7501 aggtcccact gcccattaga ctctgatggc gaaggatatt ctaggcagac aagatggcaa
     7561 gaagggcgac acacccatgc cagaatgctg caacaatatg ccgttgacgg gctgataaag
     7621 cccaaggggg ttagacaccg aagatacctt gacgggcatg agcagtctcg gtcgtaccat
     7681 tgccaagttt tatgagaacc tggatgaagc aaagccactg ttcaaacggg ctttggatgg
     7741 actgaggaag gtactcgggc caacacagcg aggccgaaac catcctacgc agcagatatt
     7801 ttattgcaga gcgcaatctc ggcgacagcc acatagggtc ccttataggg aaaagtcata
     7861 ctaggaataa atccttatca accaatctaa attttccgag gctggttcaa cacttcttga
     7921 cgcgatggaa cggctacggc atctggcttc ttatagggga gactttcatc cggaccgact
     7981 cggcgcgttg attgtgcttg cgagaagcta taagcttcag ggaaggttta atgcgagcat
     8041 tcaaaactgc gacgaggcta ttgagggctt gaaacagatc agtgtgacgc aatattcgtt
     8101 agagaggaag ctgcgagccc agaaagaaga gacaattgcg atgagagaac aggaaggcca
     8161 gctttgagcc caattatgcg ctttcgctaa aaatgggtga gctcctgtcg cagaggtttc
     8221 atgattctaa gatctatgtc tctaaaccat gaacccttga ttggatcatt tttatggtaa
     8281 aggcatttag tgcactgctt ctgtttcgca agtcggcggt aggctcggag ttttgaatct
     8341 ctacacgcct aactcagccc tagccctcag ccccctccca gctaccaaga attcccagta
     8401 gagaaacagt aaacagttgt actacagcga gtagaatccc atctcgtggc agtttcctgt
     8461 cacctcaggg atgagctcga tgcgtctttc ctattgtacg ctgctattcg atgccgtacc
     8521 caagcttata taaatagagg cttggcgaca tattgtctac taaatctaaa tgtttctgct
     8581 ggcggccgca gtaatcaatg ccgagtgaca ccagcagtgt cctgtgcatc aaacccgagg
     8641 tcaactggca ataccgaaga taagtaatat gatggggaga ggcgagccta atcttgaaat
     8701 ggctcgtgaa tactagggta tagcccgggc tcttaggtcc cactgctaga ctgcctagct
     8761 ccgcgccata gccccctaac agtatggtcc ttcctcggcg ccttgagtac atatgctaca
     8821 acgccaaaca aatagaacat gttcttagaa aatttggcag gtgtcaggaa tttttcatac
     8881 aataggcagg tttatgcttg ttacgtggct tgcattgcag gcgcctgcat ttacagatcg
     8941 tcgaggaaag gcgggcctca taggggccaa gctttgaaag gaaaagcttg gtcaacagat
     9001 cgcccctggc actaaatgca aggaggaatc gcctctgggc tttgaaatta cccggatcat
     9061 atcttctgag aagccactat tggcacacta gttcgttcgt gactgtgccc ttcggtggtc
     9121 cggcggctgt tttcggagaa tatgacgccg cagggaccgc tccaccatct caagtgatga
     9181 tataatggct acatggtaac ccggctacga aggtttgatt tcgcatcaac cgatagtata
     9241 ttagccaaat gcgcgggcct gggactatga aagctgtcct gtgcagcctg gccttcgcgg
     9301 tcggagttgc ggccaaggat gatccagact atgacccatc cctcaatttt cgaccgaaga
     9361 atgtgaccct cagcatcctc gattactggg ttggatcgtg agtttctgga tgacactgag
     9421 ctgttgcgtt gacgctgact gcgcaggtac tataacggca ccacagacgt ggaattatcg
     9481 ttttacaccg ggctggctgc caattggagc cacctgtgcc ccaatctcat caacacaacg
     9541 gttaccaaaa agtataataa ttctgtgctg ggccttacag agcccagctc ctataatgtt
     9601 ggctatgacc cagtgaatgc tttcttcacc atgtggcctc gcaactttaa tttctccact
     9661 ttacctgacc caaggtggtc atgggaatca atacaatatg acgcatcttt gaggttcgct
     9721 ttgttctcat ctgagtgagt gattccaccc aaataagaga tgtcccggct gacaatccct
     9781 agtcctacat actgggtggg gcccagggtg tctaacaact tcaactggac actcaatgca
     9841 acacaaggcc caccgtacag tttatcaagt actctcaccg attatgaccc gcttgggggc
     9901 tgggcctcca acttggccag ttgcaacggg agtgacatcg ttgagtggac cttttacccg
     9961 actccctggg atatcatggg gaatggactt tacctgcctg atgcggtgct tgatcttcag
    10021 tttgatgaga agactgctaa cctctcgtta aatggctact tcatcggcta tcatgcagtt
    10081 aaggtaggta cagagactct aagcactggg gtcctcgtag taggcaagat gaaactatcc
    10141 ttcttgggcg tcttggatgc ctatcattca gatgtcctgg ccaataacac cgctacgccg
    10201 acttggctgc gcactgtggg tttccaaaat aattctttga atgttggata cactagcaca
    10261 gcaagcagtg tatcgatggg aagagcggtt tttgctacta tcattgcttt gacagtaatg
    10321 gctggatttg tctagacgag agctatccct ctggcagctt cgtcgcggtt ataaaggctc
    10381 ttgatcgtgt acagcaactg gaggattatc ttgtcgacat ggacggattt tggtttaata
    10441 tgtattgata gatatggaag ggataagttt tgagtcatcg agtataaggg tctgctccag
    10501 cgatacggtt agattgtggt acatacaata gtttagaccg atgaagtggt actgaatatc
    10561 ttgctactac tcgagtgctc cagcttaata cggctgcatg ggagacaaga tgctgcatgc
    10621 gaatgcaaca agtgataaag actacaatat gttgctacta gccaacataa agataatcta
    10681 cgtatatttt tgaacatact tgcagcaata actgcacaag agtattagct agataggagc
    10741 aagtcatgac ccagatttag gccaggatca cgtactctcg aattatagag agacgataat
    10801 aaagatatca gatagagact ccaactacac tttgttcaag tcaacgaaaa gggcaataga
    10861 gtaagttaat ctactcaaaa tcgaaagata acacttagac tctaagcctt gtatattgct
    10921 tactatttat ctttcgtaat tctcttgtaa gttatctgcg gctttgtatc agttcttgtt
    10981 catttatccc aacatgttat aggtggctca gctaacatta gagccacact cctgctttca
    11041 aaagtggagt atctgtctac tagctggcat gtcatagagt tggttcaact ggtcagacac
    11101 cgtgaaatga ctttcggatt gaacgggcct taaaccatag tattggacct tcctatccga
    11161 gataaatgtg agttcagttg atacctggct cttcttcttt cactttctta tcttcttcct
    11221 ctgctcccct ccggccagcg gaagtctgag gtcaatctga gcaacatcgg agataagtga
    11281 ctattgcgaa ttagtccaag ggtccggcta tgcccgggct ctggggcccc actgctagac
    11341 tgtctagctc cgcgccacag cccctattga ttttctctga tcccttggtg gtggaatgaa
    11401 tacattcgcc gtggaggcat tttgttgtat atagaattat agtaggtctc ttgtaaaaca
    11461 gacagttcgt tatacttgat cctgggtgga atgtcagcct gcatttacgg atcgccaaat
    11521 agagggagcc tcataggagt caaacatgaa gggtggaaat ggggtcaatg gatcattgct
    11581 gacactaaaa cactagaaaa gatcgctttg gcgcactgga ttacccggac aaacacccct
    11641 ccagtagacc actataggtg gtctgattcg tccctactgt actactcggt ggtcccgacg
    11701 gctaatcatc ggggaaaatg ttgatagcgc atcaccatcg tttctactct atcgctcact
    11761 tattgatttg ctgatttttg aaagcctgat ctatgattat gttatgctga gaagcctgcg
    11821 taggtaaaca catcacctga cctcatgccg ttgttatcct acgctttacc ttcctttctc
    11881 atggctttta gacttgacgc gccgcctgca tcacaccatc aacaaaccga tattccatga
    11941 catgttgctt tcgggatccg gcccaatgag agaagtatag cctcggaata atgctaaact
    12001 cgcagctcag gaatccagtc gctccactgt cgcaaccaca ctttcatcag cgatgcatcc
    12061 accggaccca acgctcgcaa agctgcacta tgcttctgag cattggtggt gtccgcagga
    12121 ggacgtatct aaccctcaga ttcagctagt gacgtgaaga atcctagcag cgatgccgca
    12181 ggaattttcc gcatgacctc ctcgttgaga ttcgggtcag atagccggtt cgtgaggttt
    12241 ttcacccata ccctgagcgg aataatcttg gtggaacagg cttggctgat aatctgtgcc
    12301 aatggctccc agtggctaat atgtgggttt gtgatatgat agacctctgc atggttcgac
    12361 tctgtggaag ctagtcgacc actatgtctc ccgcagccga tttggacaat gctccgagca
    12421 gcaacatcct acagaattag tacactacag atttcctagg aacatattcg ggaagtggct
    12481 cacatacaat gggcacccaa tccactggga ttgaaccaat actgtcaggc agctctttca
    12541 tcgtctgaga tgttcgtaca agtgccggaa accagtctcg tgtcgtccac attccggcct
    12601 cagcatctgc aggtcctccc aactgaccaa cacgatgaat agcaatcgtc tgttgagttt
    12661 ctcccgcgac gaggtcacag agaacttctg ctgcgtattt cgattctgcg tagccttgac
    12721 tcagtactgt tgacggtcca tacagtgttt ctgcaatgtg atcagtttca ggcaggatgg
    12781 tagagcgacc actaacggcc gcgatggaag aaatgaaatg gaatgctgcc tgacgtggtg
    12841 agtccttgat taggttgaga agccgtcccg tcccttccag ttgagaacgg aagctggaca
    12901 atggcagatt gaaattcacc atccacgcat tatggaatat aatatccact cgctcccgca
    12961 agtaactata ttcctcttca gttagcccga gcctttcctg gctcaggtca gcctgccaga
    13021 atttgactcg agaagtttca acgagccagc catcagctaa ccgcttttca cggaatctag
    13081 cgagctgtcg ggtttccgca tctgccgaac gattgaggca atatacatgt gtgatggtcg
    13141 gatcctgcag cagctcctcc aagagataac tgccaagttc gccagtcgaa ccggtcagaa
    13201 ggaccgtctt tccgcggagc tgaaggctct gtgcctgctg ccagattgcg tgtgtcaatt
    13261 gatgctctcg tgaccaaaag ctcactgcgt gtttctcgcc ttccgctcca agatgaccac
    13321 ctagttgtcg aaacagcgta cttgcgaggc gccggaccgt cgcttgctca tagatggctg
    13381 cactagtcca caagatagat atttgcttgg tttgactcat gcgatcggcc gcatcttgca
    13441 gtacctgggc gagtcgaact acctgaaggg aatccatccc tagagtgaca atgtccacat
    13501 ctagatccac agtaatgcca cccaagatcc gagaaaccgt ctcttgtagc cactgctcaa
    13561 tgccttccat agtcgactct tgcaattttt ccacgtcgcg ggtagagcct tcgtaccctg
    13621 ttgcatcact atataatgca ttgataacat cctcatagag ctgagctgtt tctcgccggc
    13681 gaagggaccc cttaggggcc agcgcaaatg gccgatcaca agaggcaatt gcgacacgat
    13741 tatgatggat ttgtccgtga gcaggcaaca agccattggc atccttcatg aggggctcca
    13801 gagcctgctt cagccattgt ggggtccatg tctccgggag ctcatcccat ttaggttgga
    13861 ccagcaaagc cacttggaat cgatcctggc cgaaaatggc agcgcgatgg actaaggaat
    13921 gggactcaag atggtgctcg gcatcaatag ggttgagctt ttcgccgttg cttagaacaa
    13981 ttatgtcatc tgccctcccc tttgaccgcc ataggtgcgg ttttgttgga tgaggttcaa
    14041 aaagatcacc cgttcgatat tcgctaagat gtggaaaggc gtgaaatatg ccatgatacc
    14101 gacgggacga aggtcgaggg atgaccaact cccacagtcc atcaccgact tcctccatgc
    14161 gatgttcgaa ggcgggattc cattcgaagc atgcccaatc cgcggggtct tcacaaagaa
    14221 gtgttggtgt gtaaccggtc tcactgctac ccatcaatgt ctgcaggcga aaatgggatg
    14281 aaattgcgtt ccccgtggcg cttgacagtg gtgcgccacc aaagttcacg gcagacaagc
    14341 cctgcagtgc ctgtcgtccc ttttcagacg accaaagatc ctgcaacgca aatggagcga
    14401 ttaaacacca tcgaggtggg ttgggagtcg ccataatccg tgagaagaga tccggggtta
    14461 gaggccgatc tggggacagc aaaaaaggtg tctcataaaa tatgcattca caaacgcata
    14521 ctatgccaat aaagtggaat aatggtccgt ggctgaatcg catctcacct ttatgtcgca
    14581 gaaacaactg ggcggattca cgaccctggg gcacgggaag agtttgcatc tgatctagcg
    14641 ttgctagata cccatgggta agagttaccg gtttggggag acccgtagtc cccgagctgt
    14701 ggattatgat agctggacgg tcttctatat ctgcgaaatt ctcttgatgg ggatatgatg
    14761 tgacaggaga tgctgcaaag acatccccaa cgggatccat gcgccatcgt tgtaacccga
    14821 gatcagaaca agcgatttca acctggtcga caactttctt tagctggggt cgctcgctac
    14881 catccacaag cactgagcag ctcgttttta acagcaaatg atgaaaggct gcctgtgagt
    14941 tgcgagtgga taaaagtaac gcctaagcct atcagtcaga aacaagcatc gatactgtga
    15001 aacaggcatc cccaactagg aatgtgagaa ggtcataccg catggcctgt tttcatgcaa
    15061 gctagctcaa ataccaagta tcgcaagtca tttgttccga tataggcaag aacctgctgc
    15121 tttcttccag aaagcctgct gtcaatccac catgatacac ggttcacagc cgcagacagc
    15181 tgctggaacg ttatacaacg ccattcacaa tcggcatcct gggagctggg atgcaaacag
    15241 tacaagcgat caggctgatc cttcgcttgt tgatctacca gctgagttaa aagccgtcct
    15301 gaactatcag cggagcccat gttgctgtct atacaatcct ctgatgctgc taatgggttt
    15361 ttttgcaaaa gagacgtttt agactaattt atatattata ctaccccact ccatcattcc
    15421 gcagggaaaa ccacagatac gttacttaca tcaaccgtgg tatagactcg atgatcgcca
    15481 aattcagatg gctgcagcct tcatcccttg cagtacgagt aacgttctcg ctacactctg
    15541 cagatctgcc ctatcctgca attgcagtgg agatcctgta gacctgcata tagaaggcat
    15601 gtctgacgtc aaggactttc ctttctcgac ttcttgcgac ttgctccagc cgtctataac
    15661 aggcaacgct ggcatagcat acatgtacgc aagctggtgt caccagggca acttttaaag
    15721 gggccaacgc taactccgtg ataactacga tgagaagtta taggattacg tcacgataag
    15781 cacagtgcaa tcgcacctcg attattctta tgcgaatacc aggcggtagg tagatgggtg
    15841 aacgacgcat tagagtaatg gtaactggct cttcgccaca acccattcca cggcagacag
    15901 catttgcttt agctctggcc ctgatcgtgg aatgtcatga ccagccgaat gtatgattgg
    15961 cctccgagta ttcgaatcac aaagacactc gacgaggagg ccacaatcgt ccagacctgg
    16021 cacatcgttc tttccacgca ggtggagaga aggaattgat atacgagtcg gtactacatt
    16081 tgggtgcagg gcacatggga taagctcaag cgggcggtcg aggaagaaag gcaccgactc
    16141 gcgtgttata gagtgggttc ccttgatgac tttaaccaaa ctctcggtca cagagcgaac
    16201 aggttccgga agctgtgcaa tctctttatc ctttccggag cggaggcttt gctggtccgc
    16261 tgacgagaga gttccgagta cagaccgaca ataagcttca tccgcggcgc acggaatcgt
    16321 gggcgaatag aagattgcga aacgaaatgg tgggggctcg tctgggtatg ccgttttgtg
    16381 ctcgagcagg aacgaaaccg agattgcagc tccttgactg aaccccaaaa ctccgtcaaa
    16441 agggccatgc tcatcaatag cctcttcgat caaggcatgg gcagcatcga ttgaccctgc
    16501 gtcaaacgac cgcgtccagc agtagtatgg aggtgggaaa gtgctcccaa tatctatatt
    16561 cggttgatga agctgatgtt tagcaacaac tgatttgcga taaatgactg acaaacatac
    16621 ctggagcagg cggacattca acttcagctg agagaaaatg aaactcccag cttgggtcag
    16681 catctcgcat caaccccgaa agttgatatc gcagaatatt aggccccgtg ccgtagccat
    16741 gtaggcagag gattttcatt ctgattgctg cttttggtac ggtattttac cagtagaaga
    16801 tgcgattgga tacggttgga caggccagca aggctgtttc gaatcgcatc actttgctca
    16861 ccctaccaat ggattttata gggctccaag acactcttgt caggctttat gaccaaacaa
    16921 ccagtaccat ggcagaaata atcatacttt gtaagttaat tacataacaa ggatgtcctt
    16981 gcagaggctg acgttctcta tgatgtgggt atcggggtca gcatcctaga tgcctggtcc
    17041 attttcatgg gaagtatgca ggaagaccat actgttcaca aatcataggc aaaccatgtt
    17101 tgaagagaag ttacagcgac actaaatcat cgtttcacga cgccaggtgg tgacacaaac
    17161 gttgtcgatc acagccgcat gaccatgact cgccccacgg atattatcga ctgaattagt
    17221 ggcattccaa caacctactg atgatggtaa agggccattg aggaggcaag tgagccggtg
    17281 agttaccact agacgaacat tatcttgccg ttctgcccaa actctgtgac gttgctgata
    17341 cagcaagcca atacatctat ccatttaagt tctattatct tcctgacaag ggcgctcacg
    17401 ggcacttggc ccttgcgtgc gatctccact tgttggaatt ctgatgaaaa acctccggcg
    17461 gatcttattg ggctaatatc tgtacagtct gcatagcagc tcaaatcatt caatgatatc
    17521 gcagtatatc tacgtggcga tcgcgaagga catcaggaaa ggtacaaatc tggagatact
    17581 attcctgtct gatggatgga cccgctgttg ctgagtccac tcggcttgat ccactcttca
    17641 aaaccccttg tacaacctcg aatactgaaa aggtaggtgg ttgacctcat ggctaacctg
    17701 gaatttccag cctcgcagtt tcgagagtct catcgacaat atacaccaac ttagaggccc
    17761 gcaccttgcc tttccgcagc caatccaacc ccgaagtaac gccagccaga cttccaggct
    17821 tgacctggaa ccgaggagaa gcgatttggc gggtctgcag gagaatttca acggcattca
    17881 cccattgagc cccgaacgag aggttctcta gctgagcctg gacttctttg ccccccatca
    17941 gatacggctc cccaatcata tcatatgcca tggaaacatg agtatcaacg tcgcctcgag
    18001 gacagcgtac gtccagtagt gcattgtaac agcccccgga ggatgaaagg gcagcagcac
    18061 atatagcagc cgactgatta gtggagattg tatcgaaagc tagctcaagg gtatcatcgg
    18121 taacctcgcg gatttggtca cctacatgag gatcgtgata gtcgaggacg atatccgcac
    18181 ccagttcatg catccaggca cgattaactt ctgagcacgt tgtgacgacg cgcagccccg
    18241 atagctttgc aaattggatt gcgagagagc ctgtcgaggt tgcaccaccg tagatcagga
    18301 tgctagggat atcctcatca ttacccttct cgtctctctg cagatccgtg atcttatcat
    18361 cgcataccat tccagggtca gtcagctgca tggactggta cagattctga ccgatagtca
    18421 tcatgccgac gcccaagcaa gcggctctgt caatgtccat ccattccggc accctgaatt
    18481 gtatgtcccc tttcgcgatg acatactgcg caaatgcacc tccctgaggc tgcatcacgt
    18541 tacacccgtg tacaaagccg gcaacacggt cccccttctt ccaaggcttc gtgactcgtg
    18601 gtccgatggc ctcgacgacg ccggcgtagt cacagccgac gactgttcct gcgcaggagt
    18661 cgaagtcaac gtgtttccag tccgttgggt ttaaagccac tatgtttctt atcaacttgc
    18721 gcccagatac tagagatcta tttcacactt acctgcttgc gtcttcacca aaatatagtc
    18781 atcaggcagg gcgggtattg gcacatcatc ggccaaagta acttgaccac gctctcggac
    18841 aatgacagcg cgctgaacac ccatgattct tgtgtctagt gagtgctaac ctgcaagtgt
    18901 aaactcaaat cactattgat agtggtatag aacgtatcag acccttgata tgaattcgag
    18961 acccagctac tgagggcacc agtcagcagc cttaccactt ctatatagca acagattttg
    19021 tggatccgct tgacgcgatg acgagatagt ctgtcaagga attgcctcaa tagaaaacga
    19081 ctaaaaccag tcctgatcca gcaacgacga tcaaacatag ttcaagaact caaggataaa
    19141 tctggaccac aactagatag cagtccttgc gtcatatgtc gttcaattac tcttcttggg
    19201 ctcccgcatt acatgcctga atgtttgatg ccgcggccgt tctaacagca gttagctata
    19261 acgtcacttt tcgaagtcaa atctcattat gagagtattt tattatatat cgaagctgtt
    19321 aaaggaccca ggccgagagc tagagccagg gttattctaa ggaaagccag ggaaacggtt
    19381 ttattcaatt aaagtcagat tgaacaagct atcttatgac atcagtcaca atggaagagc
    19441 acgtcagaga cacttctggc ccagagccaa ttgcgatcat tggcatgggc tgtcgctttg
    19501 caggcgaagc atcttctgtt gaaggattct gggacatgct gcgcctgggc cgaagagagc
    19561 atgggcgtgt tcctgctagt cgctatcaag cctcagcctg ggaacatccc agtcacgagc
    19621 gcaaaggggc tgtatgttct gcattgattt tgaccgcttc aggatgaaac taaccacgag
    19681 gttatgatgt atcattagat caatcacgac agtggcttct ttctagccga ggatccatcc
    19741 cactttgatg cgcccttctt ttccataacg tccaaagaag ctgcaggtat ggatcctgtt
    19801 cagcgtattt tgcttgaagt ggcgtatgaa gcctttgaaa atggtaagta agttctgcac
    19861 agagtcgcag ggaatgaatg gctgagtcat gatcccaggc ggcgttccga tggaaaccct
    19921 ccccggtagt gcaaccggcg tctatagcgg atgcatgacc aatgactacg agctgctttc
    19981 aacccgagat atcatggaca tgccacataa ctcggccacg ggtaatggga aaactatgct
    20041 ggctaaccga ctttcatggt tcttcgatct ccgtggtccc agtatcatga tggacacagc
    20101 ctgttcgtct agcttgacgg cgctgcatct ggctacccag gcactacggg cgggcgaatg
    20161 tagccaggta agtgagctgt catatgcgat ctgatgatga tgactgatta ttgtaggcgc
    20221 tggtgaccgg agcaagcctg atattgcatc caaactttac tcagcggctg tcgtacatgc
    20281 atatgctcag cgctgatggt atcagtcact cttttgatag caaagctaat gggtacggta
    20341 ggggtgaggg attcggtgca atcttactca aacccttgtc caaggccatg gcagacggtg
    20401 acatgattag agcaatcgtt cgcgctactg gctctaatca ggatggacgt accccgggaa
    20461 tcaccatgcc gaatgcaacc gcccaggctg atttgatcag gtcaacctat tctcgagctg
    20521 gattgtcgat gggagaaacc tcatactttg aagcccatgg gactgggaca gctattggtg
    20581 ttagtataag actcattgtt tcatgacaag gtactaacaa cgtcacgtag gatcctaccg
    20641 aattgtctgc cattggtgca agctttggag ccgagcgaaa gccaggtgac gagccacttt
    20701 gcgttggatc cgtcaaaagt aacctaggac ataccgaggg tgctgctggc gtggccagta
    20761 ttatcaaggt ggttctttgc ttagaaaaag ggatgctggt tcctaacgca ggcttctcga
    20821 acctgaaccc taagatccga ctggaggaat ggggcttgcg cttaagcaac agcaccacac
    20881 cgtggccatc tcatttgctg caacgtgcga gcatcaactc atttggcttt ggtggtgcca
    20941 acgcacacgc cattctcgag agcacagctc agtaccttgg taagacgcaa gctccgtccg
    21001 actctaccat agaaggaaca ccccaggttg ttgtggtatc cacgcatgac cagtctgggt
    21061 tagaccgtac ggccgacaaa tggacgagtt tccttaatcc gtgcgtcgat ggtaaaagaa
    21121 aagacattgc cttgttagat gtagcacaca ctatggctac acggcgatcc cagcttccgt
    21181 tccgcagctt tgctgtggtg aactcactag cagagctgcg aaatgtgatg gccgcaggct
    21241 tgcccacttt ctctcgggcg agccgtaaga accaggcgca tctagcattc attttcacgg
    21301 gccaaggtgc tcaatggcca cgcatgggtg ttcagctact ggcaaaccca gtgtttgcgg
    21361 ccagtatgga acgaagtcag caggtgctgc agagcttgga ctgctcgtgg gatttgctcg
    21421 aggagatccg cgcaggggcg acaacaagcc gtatcaatcg acccgatcgc agtcagcctt
    21481 cttgctgtgc tttacaggtg gcattggtag acatgctccg cagctggggg gtaactccta
    21541 aggcagtagt gggccattcc agtggtgaag tcggtatgtc tctctcgatt cgtccaactc
    21601 ttgtccaaga aatgactgat atgtgtccca ggggccgcct atgcggccgg ctatcttaca
    21661 catgaggatg ccattcgaat cacgtatttc cgtggcgtgc tgtctcaacg gattgctgag
    21721 agtgaaagcc gcggcggtat gctcgctgcc ggcatctccg ccgctgatgc gcaggaatat
    21781 ttgcagacct tacccccgga gtccgcggtg gtagcctgtg tgaacagccc atcgagtgtc
    21841 actctttcag gcaatataga agaaattaac ctgcttgaga agcgcttgca agcggatggc
    21901 tgttttgcgc gcaagctgcg cgtagacact gcttaccact caccgcatat gagagcgttg
    21961 gctgatgact ataagacagc cattgaatcc attcagccag ttgacaagta caatggctct
    22021 atatctatgt tctcatctgt cacaaaagag ctcttgcagg cagcggatct ggacgcgtca
    22081 tactgggtgc gcaacctcgt tagcccagtc gagtttgccg ctgcagtcac caaagttgct
    22141 accatgactg aggctggcag ggggcgaggg agacgacgag tggtcccagt caaatgggca
    22201 ggctttttgg agattggccc acacgaagct cttaaagggc cgttcaacca gaccctgcag
    22261 gaagccaatg ctgatttggc ttccactcct tacaagagtc tggtgctccg caagcaggat
    22321 tctcgacaga cagccctcca agttgccggg ctcctgtggt gtttgggcta tgcaatcaac
    22381 ctagatacag caaatcaaag ctttctggag agcagaaggc cacaggtgag ccgagacctt
    22441 ccatcttatg cctggaatca tcagtccacc ttctggcacg agccattgga atcagcccgg
    22501 ctgcgacagc gcaaagaacc ccgtcacgac ctcctcggta tgccttggga ctaccagaac
    22561 gagctggagc cgcggtggcg taacttcctg cgggtgtcgg aactgccctg gcttgcggac
    22621 catgtggtgg ctggctccat tgtctatcca gcagcaggca tggtgtccat ggtcgcagag
    22681 gcagcccgtc agcttgcagg cactacgaag tggctagagg ggatcgaatt taacgatctg
    22741 gactttttcc ggggagttgt aattcctcca gacgaacggg gtctggaaat agttctccat
    22801 gtcgcgccgc atcacggcat gaatggatgg tacgaattcg gcatcttctc cttgcccgag
    22861 aactcctcct gggttcagca tgcgaaaggt gcttttgctc cacaatatgc tgatgaggat
    22921 ggagttggat gtgctgcaga ctggcaatgc actgtacaac gggttcgaca gacgcaagct
    22981 atggcaaaga aggctgagat tgaggccgtc tatgaatggc tgtcagaaac gggcggcgtc
    23041 actctggggc cgaccttccg gtccatggct ggtgtagctt ttgactcgga gtctcgtctg
    23101 tacgttactg gagttgcacc gaacactaag cagacgatgc catatgagcg tgaatctcca
    23161 tgtcttgtcc atcccacctc tctggacagt ctattccagg cggctgtggt gtcatgctca
    23221 gatgccctgt ccaatcacaa tgccaatatc cccgtgggag tagagcgcct ttatctctcc
    23281 acggccttct ccttgcagcc tggtgatcga ttcgatgtcc atgtcgagac acgctatgag
    23341 aacggcgtgt cattcacgga gtcgatcgct tcggacccat cctggcagca gcctggaatg
    23401 gttctgcaag gggtgcgatt aggtcgcgtg cccacgcggt ccggcggctc gaccatagag
    23461 gagatccagc aaagccgatt ctcgacgctt cattgggctg agcacgtgga ttcttccggt
    23521 ggtctagaag gccgttgctc tggtggtctg cagaactggc ttggccgggt ctgccacact
    23581 catggagatg ctcgtgtcct tgtggtgact accaaagaca taggtcaggt ggttgaagct
    23641 ctcagagact atgcgccgaa acgcagtcat cgacctcgac tccaaaagct caccattgtg
    23701 ctatctgacc ctgacacaga ggcattaacg aaccaggtta aaatcattaa agattcccta
    23761 gatgggtgtc aggttctacc agttgcctca ttgcaggata taggcacgga cttgctgggc
    23821 gaaaccgcct atgatgcgat cattgttgat catcccgatg tctggagtgg agacaataca
    23881 aaagcatttt tcaactcttt gctttcgatt actaggcctg attcttggat tgccgctcga
    23941 gcgactgctg aaaaccacga tgcggccatt cgcaatgcgg gccatgcgga ctgggaagta
    24001 cagggctcga ttgaacagcc cggctatctt ctcatccgcc gtcaacttgc tccggttgag
    24061 ttggatccca ctatctatat actaagcagc gctgcggctg agtcggtcgg tcctctcttg
    24121 tatgagctgg atggcgtcgt aaacaaactc ggttctaaga ttgagctggt ggatgtcgat
    24181 aaagctcccg atctgaagga gaaaatgatc atctcactgc tcgagctaga tcgtccatgg
    24241 acagtgaatt ggacgcccga tgagatatca cgctttcagt cgctgttaca ggcaaaatgt
    24301 ctcctctgga tttcacagtg cccggggcat gaggcgtccg gctatgcagg cttcggggct
    24361 acgactggac ttttgcggac cgtacgcaat gaaaatcccc atatcgtgct gcctcaatta
    24421 cttgtgtccg gaaaggataa ggatcctcac aatttggcgc gcagtatcgc acacgtgttg
    24481 cagctaacat tgaaacctcg gtcacggcca cacgacttgg agttctatat gcaagacaat
    24541 cgtctgcttg tgccgcgggc tatcacggct cgtgcagtag atgagagcat ggatgctctc
    24601 ttacgtggcc cgcgccctac gctagcagag ctcgcgcagg actcgagacc gctgcgcctc
    24661 tgcactaagt cgcaggatat cagtgacgcc cggtgggagc tggatgaacg gttgaattcg
    24721 gccttgcccg atgatttagt tgaggtgcag ctacataagg tgtccatctc tgagctagcc
    24781 agtaagagcg gtatctctcc ggaggcgcgt atagcggcca tagaagcagt cggaattgtt
    24841 cgccaggttg gaatgtctat cggctcagca ttccaagtgg gagacgaagt cttgtgtgcc
    24901 atacccagtg atgcgtggcc cagtgcttta accacccatg ttcgcctccc agcaagtgct
    24961 atctggaatt cgccatcaca gcagagcgag acacaatcag tgtccatgcc ggtggctttt
    25021 gcagctgcct acaccagcct cttcggcagc tccggagctt ctgcttcatc tgttctcata
    25081 gttggctccg ttagccagac cctgcgagcc acggttgact gtgctctggc tgcgggtatg
    25141 caggtgtacg tggcggtcga tggcgaggat gggattaatg ggatgcgctc taaatatgta
    25201 ggattgcatg agagaatcat tcctattcac agggagcttg atacaacagt caaacggctg
    25261 actgggggca aaggagtgga gctgagcgtt tgctgtctag gaggttcggt cagtcgactt
    25321 gcagcgcgtt gcttggccta cagcggccgg ttggtcgacc tcagtgaaga gctgaaccta
    25381 gctgccctgc ctcagacatt cgttgaccgt gggtgcactg tcagctccgt acggttatca
    25441 aggatgctcc gcgaagcccc ccgtcagctg caggccaact tccatcgcgc agtggatctt
    25501 ctcggatcag acgccctcgc cagcgttcag gcttatcaat ccttccctgt ttctcaggtt
    25561 gcagatgccg ttgctcatgc gcgagacagc ggtacccgtg cgattgtcga tctccaggct
    25621 ccgggtcagg tgccaattgt gccagccctc ccagatcctg cccctctccc tgcggagaat
    25681 acctacatcc tggtcggtgg actgggcact ctggggattg cactagccag tacgcttgtt
    25741 gactgcgggg cccgtcattt ggtcttcttg agccgttctg gggctgttcg ggagacacag
    25801 caaactgcgc taaaagagct tcaagaccga ggtgcgcgta ctgatgtcgt gcgctgtgac
    25861 gcggcctgtc aagaggatgt gaaaagtctg ttgacccgag ctgaaaataa tcgctggcgt
    25921 gttcgtggta tcgtgcaatg tgcaactgtt ttaaaggtaa gtcagttcgc agcccagtag
    25981 cgtcaccaag ctaaatttca ccttaccagg acggcatgtt cgagcacatg gacttcgacg
    26041 cgtggaagca atccaccgag ccaaaagtcc aggggacatg gaacctccat aaagcgtttt
    26101 actccacccc gctagacttc tttgtgactc tgtcatccat agccagcata accggaaaca
    26161 tgggccaggc caactacgca gccggcaacg ggtacatgga cgctctgatg atctggcgac
    26221 gcaagcacca cctaccagga catagcatca acatcggcct agtcccagat gccagcggag
    26281 tgagcgacgt agccgaaaca cccgagcagc gacgccagcg ataccgacat ctagagggta
    26341 cagagattct gcagcgtgag gttcaaactc tgctgcgcgt gatagtccag aaaatcaccc
    26401 gagtcccagc acaagtcatc gccggcctga cggacaccct gccgcgaacc gatggggcag
    26461 cttcctggca attcgatcgc aagttcgatc accggattca agttgttgct gatgaggatg
    26521 cagcagctgg cgtggttaag accagcacgt tgctgaagaa ggcgcagtcg gtggatgagg
    26581 cggtacgcgt tgtgaatcag gcactgcagg agtatttggc cagagcgatg gcgtcgtcgg
    26641 cggaggctat tgatttggag ttgccttttt cggcgttagg tggtgagtat tttgactata
    26701 ccttaaattg tttcaggatt atgctgacgc ttggggtttt aagttgactc gctcaaagcc
    26761 gcggaggtac agaactgggt cagtcgcgag atgggcgcgg aattgtcctc gtttgagttt
    26821 atcggggcac agccggtgag ggtgttggcg gagaagattg cgacgttgag ttcgtttgtt
    26881 gttgctacgt agtttgcatc gcttaaggtt ggtttcttcg ttatatgtcg ggtagaccag
    26941 gttaattagt atcgtattat tgctattaaa caccataaga aaacaaagta tttaccaatc
    27001 attatatatt atgtaagtcc atcaccagtc tacttctccc ccctcatcat cttcgccaac
    27061 tgcgtagtcg cagcccggcg cttattcacg atatccaaga acacttctgc aggcccaaga
    27121 cttcccacaa cgatttggtc ctttccgtcc agtagtccct gaaatgcttc agccgtaaat
    27181 tccttcaggg gcataccgac tttacggccc tcttcgccca tataatcgtg gagttcggct
    27241 gcagtgatag ttagtcagat aggaaatata tatctaggac aactagatga acgagacggc
    27301 agtagaagca gagaattggg ggtttagact cacattgcac cgctggcggc gacacctcaa
    27361 taatcttcac agagctttta cgcagctgat cccgcagaca gagaatgaag gcgttcaggg
    27421 cagccttgga ggcagagtat gcgggcatcc aggtcgcagg gactatggag aggttggatg
    27481 tggtgctgtt ttatggttag tacattttag tgcattctgg tagtgtaacc tgaaagagat
    27541 gaagaggtac gcactaaatc aagctcgtat ggcccccttc cttggtaaga taaggcaaga
    27601 aagcatgcgt cagagcaaca taactggtga agttgacgtg catttgcttg tagaagctgg
    27661 gtaggtcgaa tttttcggga tcggtcatgt cggtaggaag cattatgccg gcgttcataa
    27721 agacgctgtc gattgtgggg tatgtggtca ttattctatt gaagatattc tcattagcca
    27781 tccattcaat ctagatgcgg tactgcatag tatatcaagg gagcgaaact tactcagcag
    27841 caaacccagg aatcttatcc aagtcactaa tatcgaattg caccgcattg gccttgtctt
    27901 ctccgtgttc ttgcaagaat tcatccaagc gctctttgcg tcgtccgacg actgtgactt
    27961 taacttcgga ttgcacgaag cgcgatgcga gagctcggcc gatgccggcg gtggcgccga
    28021 ggacgaggat gtgcttgtat gggaaggaca ttctgcttca aactgaattg gattggattg
    28081 agttcagctg agtatgtatt gtatatgttg gactgagttc agttgagttt gaattggatt
    28141 gagtatgttg aactggtcat cataactctt atatactttg atagaccggt ttccatcatt
    28201 gctccactgg gaatagtggt gattggcagg accggacagc ggagatggtg ggccgaagtc
    28261 gatctccggg gatttagtgt gtgtggttgt cggcttccga acctaaagcc ggcatggacg
    28321 gacttcgtcg gctttctgaa atagcttcgt ctggggtcgg tcggagatca gagtataata
    28381 tgaaggattg cggagatatt taatgttgca taaatatgca gtgattatga ttataaacaa
    28441 taaacatagt tgtgcgcaag acgtgatcac cactactgtc aacaccgtcg acttgtatac
    28501 agagctgcag ttatacttca agtaacccta tgccgagacc tccgttataa gatattcatt
    28561 ccagcacact ctacactact tgaaacccgt gtctcactcc aattttcgta aaatgttcaa
    28621 actcacacag ctacttaaca cagcacatgc cccctgtagc caaatcccct catagtaaag
    28681 agcagccatc acgtggcgta gtgccatctg cgtgaataaa aaaatcactg atgtcccaga
    28741 agaggcaacg cgtctcgctt gtagacgcgt tgtatagaac aggtaatgag ggcattattc
    28801 tttctcgcac aaacacagct tcttcttctt cttcttctac aaggtgaagt tcctgatcat
    28861 ctcatctctc atcttattcc tcatctctca tccgcatacg cttccatcaa aaactatcta
    28921 tctatccatc gctggtatac agatagtcaa tcatcatgga tagtgcattc ccgaagcgtc
    28981 cctccttcgt gagatacgga ccatacacct acgatgacta cggagtcacc gtagccaaca
    29041 tccccagagc atcatcccag acgctggcaa cactcttccc cacgaatccg gtcactgcac
    29101 ccagcagaag gcccgtgaag cggtggatag cggcccagct ccaacacttc ggcattccct
    29161 atcagccatc taatactata gctcagctgc tggctctcct tgaaagagag tacaaagacg
    29221 gaaaggtaac actcctccac cctctcagtt ccagacaaaa agctgaccaa agacgaacag
    29281 tgcagctacg agtcgccttc agtccgcctc ctcgacaaaa ccatgtacga aatgtacaat
    29341 gccgtgcagg aggcctatca gcagcaaaag gctgagtggc ggaagaagaa gttcgctcgt
    29401 caggtctctc cttccgacga agctctgttc gatccttttc tttttatggc caagtacttc
    29461 ctcgacaagg agaacggagt gccggataaa accaagcaga cagaggccat tgtcttgcac
    29521 aatgtttata accagcagtt cgtgagcacg gctctctcca tccccggtct gagcttccac
    29581 atcagccacc cggccaccgt catcggatgg gcagacacct tcgaagaagg cttggatgca
    29641 ggcttcgcca gtctgtcaca gaaccacgtc aaggaatatg tgccgacctt tgaggcgaac
    29701 tttgatcact gccgcttcct gaccaagtat ttcctgtcgc ttgactatcc ctatgaaatg
    29761 ggtgtccctg cccgtgacag aaccgtggag cccgtgcagc ttatgcccca gctgtatttc
    29821 gacgtgcgcg agaaactcag aaaggaagtg gccaatatca acggtctttt gatcgctact
    29881 acccccggtc gaggcggtac ctggacactt attacctgga gcgagtacgc agacaagctc
    29941 accggtgtag tctcgaagat ccacgccgcc agtatgaatg agaagatgta cgacgatact
    30001 ctcatctctc tggtgtggca gtccaagctc agtcgccata ccctgttcaa gcagtgcgtg
    30061 aagcccaaca acaacacttc ggcgttgaga ttgagccagc tgcagggcca atatgtcatc
    30121 cgctgcaacg ccatcgatcc ctggggctac gaggacttct ctcttgacat caacgcgccc
    30181 cgtcgcaacg atcccgccgc gcgcgccacc ttctctctcg gaaaactgca gggggctatg
    30241 atcctcgctc tagactgcga caaagtagac cagatgcgca agatcctgga aaagaaaagc
    30301 accgccactc aacatagcaa tcccgagtcc gatgatgata atgagatgga cgaacacttg
    30361 accgtccacc gattcagaga cgacgacgct aagtggcgag tctacctcca gtacgcaggt
    30421 acctgcaacg gtcttaacca ggtcgatgag cacaatgagc aggtcgggtt cattgatttc
    30481 aacgttgacc ctgagcgaag tgacgatgat gagaaagctc tgggctatgg tcttgcgtac
    30541 ggacgcggtc ttatcgtcgg tcctaagtat atgacttcgc gcaagagcga caagggcgag
    30601 attctggaga ttgaggtctt caagtggact agtgataccg tccgagtcgc ggctgagtgg
    30661 aatgcgttta acttctgggg tggatttgaa gcccgattca gagttggtga gagagctatg
    30721 actatgacca aggggtatga gctttagctc tctctctttc tctctctcac tgtgatgctc
    30781 tggtttgaag tgattgttgc ttacctcttt cttgtttctt ttttatttcc ttttcttctt
    30841 gttgtcttct gaaaagagaa aagaggaaag agggaaaaaa aggaagaaaa tatgtttttg
    30901 tcctcttgtt tgttattcga ttgtttttcc aattctgttg tttgtgttct gttcttgttt
    30961 cttattctga aaagttgtgg tatgattctg attctcatgt acgatggatg gggaaaaaag
    31021 tgagctgatg gcgtcgatgg tgttcggttc ttatttcttt ctttttcttc gcttcatttt
    31081 gcgtgtttga atatacccaa gggatgtagg gcgggcgtct tcttcttctt tttttttttt
    31141 tttttttttc ctcttttttc ttttttcttt tctttctctt aatgaatgga cgagccatga
    31201 tgacgatggt cgggagatgg acgatgtgga tgagagatgg ctcttgtttc aactgatgat
    31261 aggatgatgg gggaagaaat atcgagatgt aggtatgtat ttcagataat ggtcatcaac
    31321 cttagtgaca gttaatgcaa ttcattgaat tgggacttgt gcgtttgcat taccagtccg
    31381 gatgtaagcg tttccggcat tccgtcttca tcttcgtttt catatgggaa ctactagcta
    31441 gtatttctca attcaatatg aaggcagcaa acgcgcagag agcaattacg ctaagtacac
    31501 cgtaccctgt gacctacaaa cctaatcccc aaggccaggg tgaaagaata aatgagagaa
    31561 acattcatca gctgcacacc aaaccaatgg aaatgggtaa ggatatcaat tcaaacatct
    31621 gcctaagacc actactacat ctgcctaaag atggtacaaa tcaccggtag aacgacgctg
    31681 ggttagatac atccgtttga gacgggttat atgcctggta tcctccgccc gcgttcagag
    31741 caggataagg tgtcggcgtt gtggatgtac ctgggacagg cgggggctgg tgcataggcg
    31801 gcggctggtg tgaagggtaa gggggctgtg cttggtgggc agggggtctg gaggcgtctt
    31861 caggagtgta gcctgaggcc gggtattccg ggtgtggttg ttgcgactgc tgttgcggct
    31921 gctgctgttg ctgttggaaa tgctgctgca cggcggccgg gacctgcacg gcgccgggat
    31981 atggtggtcg ctggctggca ggatgctcaa ccggggaatc gtagaccgat gtgccgagtt
    32041 cttgcggatt ctcgtatgtg gactccggac ggtggtacac gggctggtag gactccgagg
    32101 agggttgacg ttgctgctgt ggttgctgct gctgatacgg agcgccagca ggtggtgtct
    32161 gacggggatc gggcgattgt gaagtgggag gatatgcgtg tgcttgttct gtgccgtaga
    32221 atgcgggcgc gttggccgga ggggcttgtg tttctgctat gtgtttgtta gacatgagct
    32281 gagaatgtat ccatgcagca cccaccttga ggacggggac tgaagtagcg ttgaggatca
    32341 gcctgtggcg gcccttgagg atatcccaca ggagcagcac caggatagcc gtaaggaggt
    32401 tgagccggcc ggccatactg ggattgtgct gggtgcgcca tggacgcctc cagcagagac
    32461 tcgtaatctc tccgcgcctt gatgaacttc tcgttgagct gcgtgaactc gtctgcaaag
    32521 cattagcgga gaatagcgac atgccgaaat catcttaccc tttttctgcg agtattttcc
    32581 aatgagctca atcagcttgg ggcgaatggc caatgtagag tgatacaggg ccgtgatttc
    32641 ttcattgtcc tgcacattca gctcggagct ccgagtgctc agaagagtca acagcttttc
    32701 cacattttta atctgaccga aaacatcggc ttccatctgg gcttcccgct gcaactcctc
    32761 caccgtcggg tcaggaagtt tctcgacgta gttaaggggg aagatgccgg tctggcctct
    32821 caaggaaccc ttccaccaat ccttgtagac ggactcgagg acagcgatga catctccctt
    32881 gcggaactgc aattcaccgg gttctgaagg ctgaaagtcg aacagggctc tcacgcgcga
    32941 cactgtggcg gccgaagtac ccgacgggac tgcttgggag gtggcagcag gtgcctgagt
    33001 ttggttgact ggagcagcgc tggagctggc ttcaggctgc ggcgcagggg cgatcgtggc
    33061 cttttctctt atcgaaagtg cgagggccat ttgcagctcc tcctcttcct tttggcgatc
    33121 tgcatcggta atttcccgct tcccgggctt ggacggtggc tgcaggttcg ggtctaagat
    33181 agtgagcttc tctccaacat tcataactgc taacgatctt actctgagtc ttcagtttca
    33241 tgtatgcttg ttccatgatt ccgaaatctg ggttactggc gaacatctcc gtccattctt
    33301 gcatgcgttc taggatcttc gacttgacct gctgatgggt gttctgctcg gtataagtgc
    33361 gatgctcttc atccgtgaaa gtccaactta ctctgtcatt cgctagacgt agcagagcat
    33421 cggtgaagct cctagaagcc aactcgcgat gaatcttggg accgcagttc tgagcgaggg
    33481 cgttcgccaa ctatagccgt atcagtacac gtaagccctc aaaactcggg catgccaccg
    33541 gatccagcac gaacctccaa agtataaagc tgcacattgg cgtttctgtg cgcaagtctc
    33601 ttgatcatag cggcgacggc atctttcgct ctagaaacaa atccactgtc agaatgacgt
    33661 gcaccgaaaa ggacaaccga acggcgaagc ataccctgac tcctcggcac caactttatc
    33721 gcaaacatcc taaacacaac caatagctcc agtcagatat atatccttcg gccgatgcat
    33781 ggcagattta gcgatcgtgg ggtttgcgta ccaggatgta ttcccagttt tcggaggtca
    33841 ggttctcgtc ggtcgccttg gctataccac atcgctcggg ttagcaacaa gtataagaga
    33901 gtagagctgc acggcgtgca acagaggatg tgtgtttcat accgactgca tcgtcaaagg
    33961 cgttttgctg tgcgcgaaac atcacggggg ttgtctgcga gcgcccgggg caatctcact
    34021 gcgttgcaac tcggactaat attccacacg aacgcgtggg gtttgattcc gcggtatgaa
    34081 aaaaatgtta cagaagctgt tgtgctcaag gaatgtattc cagtaatgca ggtccggttc
    34141 tctctccttg ttgtaggttc gatggttcac ggtatccagg ccgcgagatg acacccgatg
    34201 cgggggacac tgcggtcagc gggagccgga gtaaacgagg tcgggatcaa ttgaggcgct
    34261 cgtggatcaa gatcccttaa cagacggggg aatccaccaa gacagattat cggaccacaa
    34321 cgaaggacgg ggaggagaag atagcagctg gaaagccaag gggaaaggga aagacaggct
    34381 gccacctgat gtttagcagg tgatcgcgcc gacggagagc agcgcctctg acgctgactg
    34441 gccgcgctac gcccgattaa gcgagacccg cccctttatg gtctagtggg gcaccgcctt
    34501 ccattgacgt tggcaaacaa tgacgatatc ctactagtac ttaaaacaca actactgcga
    34561 gaggtctcaa gggactgtta tgaaaatata ccccgggtga ttcctgatga ttgatcgaaa
    34621 ggtaaataaa agtgacatcg tggtcttcac gataaataac aaagaataat aatcatgacc
    34681 atccctcaca cataagcaat agccccatgg cactaaagat ccctctatat caatgtaacc
    34741 gctcaaataa taatcgtcaa ctcagaacaa gacagacaaa agctccacac ttttgttctt
    34801 ttttgtcgtc aaaacagtcg ggaaaatgcc tcataaatca tcaagaatat cggtcgctgg
    34861 aagatatgga gatgggaaca acccaacagc tgcacgacaa gtaacaataa gatgggggcc
    34921 ggagaccacg ccgaccaccg gcgcccgttc attatatgaa gcttcaagcc tcctcttgag
    34981 cttcggctcc gtgacaatag taagcactca caaacgacaa tattgacaat agctggacgg
    35041 atgtccccag gagattgtac aggctttttc actcgctcaa aagccaacgt cgaaagaaag
    35101 aatcttgcag agaaaactcg tcaagaagga aggatatctc cgcaggtgtt tagtggccag
    35161 cgacggaaat caagccaagc aaaaaaaaaa aaaaaagtaa accggataga caagtcatta
    35221 tccgatgagg tcatcgcctt ctagacattc acaggagatg cgaaactgcc aacatgagta
    35281 gctgcgaaaa agggtcggcc ataatgcaat gccagcgtca ttgtccagca aatatgaaat
    35341 atcagggggg taatgggtat ctgagagaga gaggacagaa gacatcgacg tatatagtaa
    35401 cagttgaaag tgacggcacc taggcgcctc ccttttgagc tttttcctgg gctctgctag
    35461 cccgcgcagc cttgacaagg ggcgagagat gattcagggg cgcgcaaagc gacataaacg
    35521 gatgctaatc gagcagttag ttattatttc acaatgagct tgattgacgt gaacatacct
    35581 tgagcaagtc atgtgccgag gctcgcttct caggatccac cttgagagca aggtgcagga
    35641 aatcacggaa gacgggcgac aagttgtgct catccttgat tgtaggcgtg ccgttggtgg
    35701 caatcaagta cagagccctc aggggcgatt ccgtaagata aggaggctca ccctcgatca
    35761 tctcgatggc catgataccc aaactccaga tatcaacctt gcggccatac tcctttcgag
    35821 taacgacttc gggggccatc caatacggtg taccgaccat ggtgtttcgc ttgttatgcg
    35881 agtcgttgat ttgggcacag aaaccaaagt cggctacagg atgtcagaaa atgaacattg
    35941 ggggccatcg cgaaaggtag cttactgagt ttgatgttgc cctccattga gagaagaatg
    36001 ttgtccgact tgatgtcacg gtgaatgaca cctttcgagt gaagatgctg taaaccactc
    36061 aaagtctagt aaaggttagg agatgcgaga tacattaagg agaaagatgc agtaagctta
    36121 cctctctgca gacagcagca atttgccctt cactcataat gttgaaagta accacatcag
    36181 tcaaactgcc accctccatg tactccatca ctacccagag gtccagacca tggaggtagc
    36241 tgtctaagaa gttgacaatg ttcttgtgct tgctgtcctt catgaccaaa atctcattga
    36301 tgatcagatc cttcttgggt tgcaagtcca ggttcatttg cttgatagca acacacttgt
    36361 tggtgttgtt ctcgtaggca gtgaagacac caccagacgc accctggccg atcttgttga
    36421 gatgatggta tagcctagta gggtccccgg gcgtacagat ggcaagtagt cgcgacctta
    36481 tatccatcgc attactctga cgaggtcgct gccgggggcg agcggcagga gcggcgcgtg
    36541 cagcctcatc caccggggag acatggtggg gtgggctctg caccgaaggt tgcttctgtt
    36601 cctggcgagt aggctgctgt tgacgctgac tgcggctacg gtcgagttgg atggtcgcaa
    36661 ttgcctgctg ggcggcggcc attgcttgct cttgcttttg ttggtactga gccggcgtag
    36721 gaacattgtg tgactgccat ggtacggggg taccattggc tctggagttt gatctgctca
    36781 actgaggctt aggttcagac tgcaggggct ccgtttccgg aatgggaggc gtgtcgaact
    36841 gcggaggaga ataggcctct tggggtggac gtgcgggcgc ggcactgtat gatcccgcgg
    36901 ttggtggctg tggtgcaggc cgagacgggg tgatattggc aggggtcgga ggttttggtg
    36961 gtgctcgatt ggggacaaag ccacctaccg ctggggtggc cgcagaaggc ccacgaggaa
    37021 taggaggcgg cgcacgtggg ttttcgaagc taccctcatg attctgtgga aagcgaggac
    37081 tcgtcggggg agaagtccga gctgaggtag ggccgtaaga cccggcgccg acagcattag
    37141 tctgtcctcc ggaaatcggg ctggaaaccg actgcggctg aggataagcg tggtcaaatt
    37201 tgtgccacac ttcgtcatcg ccttgagcat tcttctcgta gaacctcata atatcaacca
    37261 tcgtctgcgg gtgttcctcc tgctcctttt tcgagatacc gttttcttgc agcagccgct
    37321 gccattcctt cgggaggcca gtgaactgac cggtctgatt gtcatagcca acgtgcgtaa
    37381 cgtgcacggg gttctccggg gcggagatct tgatgcctcg gggggagcct aacatgctat
    37441 tgacgaagct ggagaaactg ctctttttgc tcctgcccgt gccaaatggc cgcgagccaa
    37501 caccaccacc accctcatcg gataaacgtt ttggattcgc cgggcgatca ttgtcagtcg
    37561 tcctgtgcac gaatgtctcc atccggttct gtagagccgt gaagctagca gactgtctca
    37621 atcctcggga gtccgggctg gtggccgatc ggaggttggg gggtttttgg ggaacggtct
    37681 cggtggtatt ttcctgcaat gaactgagca tgccccggct gtcaaacggg ggtccgatca
    37741 attcatctga actttgctcg gtgagagaga atcgacccga gtggggaggg cgggatttgg
    37801 aggggttgga ggtgttcgag aagtatccag gttggttgcc agcgagcacc ggagacgggc
    37861 cgccactatt ctgctcgagg gaggatgaag aagatccgta ggcgttggac cttgtccgcg
    37921 agtgctcacg actcccaccg gtggaggaac gggggtagac gggcgctgaa gggtgccgct
    37981 ttagtgacgt gttgctctgc tggctcttga ggatgcggga gctgaaactc ggaggatcct
    38041 tgtgaagctt gctagacgac cgtcgaaatt ttagggagga gaaactatcg tgattcatga
    38101 cgtgcaagtt ttagggggag agtgggtttt gggggggtgc gtggagggac aggtcggccg
    38161 actggcagca gcagcaccag cagcagtgca gcagcaccag cagggttgag cgactgggga
    38221 tgggtggttt gattggaggg aggggggtgg gaagaaagcc accgggtgag gcggtgcgca
    38281 gtgcggtagg taagagtccc taccgtccgt ttcgacgata gggtggacga acaaggccgc
    38341 taggcgggga ttgggggggg ggggttgatg gtgtggtgat actgcacggt cagatcgata
    38401 gccccaaccg gatgagtatt gttggatgaa cggaggaatc ggagatgtga gaaggaccca
    38461 gaatgtctga gcgacgcaag ggagggcgcg aaagtagcag ccgcggacta ccgtcaacca
    38521 gtggttagca cgtggagagc cgctggatgg atcagagcag agaaagacgg agtcgaccaa
    38581 cagaggcggt gactggctct gagggataat ttggggagga taaaaaaaaa agaggggaag
    38641 gggaggggaa taatactggt agggaaaaat aatagggaaa aagcaagacc aggtgagagg
    38701 gtgattcact gagatgcagg aaaagctgca gataaccgac agctcagcac acagatctgc
    38761 agcgccaaaa aagcaataat gcaacagtca ctgggaaacc aacgatgacg gagaaagaag
    38821 tgggaaaagc acggagaatt gccatggggg ggaaagagtg aaagagggta actagttaag
    38881 aggaggatgg agggaggagg agggaaggac ccagcaaggt gctttttagt tttggagact
    38941 tgggattggg aggtcgaacc agtggcagca gttcaacaac ggcccgtctt gagagtcagt
    39001 ccgacgatta ttacactggg tactcccgta ctaccatcag aataacgggg cccagccact
    39061 gaaactgact tacttggcct caggtgtgat ggggaccatt taatatcgtt tgggcttagc
    39121 agagagtagt aatttactgt gatttggttt gggtacggta aagtcagaac ttaagctgca
    39181 gttatttaac ttcctacttt cttcttacaa agtattaact tacagtgaga tagagggtag
    39241 atacaaatag ttaccctcga aaggacaaga gaaagagaca acgacgtaga gaagttgtca
    39301 atcgggcggt caacaccatt ccagtcaatt accaaagcaa gccaacaaaa ataaaggaaa
    39361 gcgagaaatg tttcgggtgc ctattttctg cctttccgtt ttcccctaaa ttgtccaaca
    39421 ataaataaaa acccagttga actgctgtgt acagataatg aatattcatt ctcaatccca
    39481 gaatattcca aacattccct gatggatgag tttggatatt atttttccgg ggatggggct
    39541 cattggagag attgttcccg tacttttttt ttgtttctgt ttcccccccc cccccccccc
    39601 ccccctcctt caaatccgaa gatggaaata ttcttctggc agcttaagtg tctcagatac
    39661 cgtaggtccg attaggcaaa gagaaaaatt ctagacacgt ctttgacccc agtttgcgtc
    39721 ccgttggcgg gtggatcgcg aacagatgcc tttcctttct cggaacgatg ggttccaccg
    39781 gttttccgct ttccttctgc ttctctttcg acacctcgga tatgagacag attccaaaga
    39841 gttgaccgat ttcagagata tgaaaaggag ggtgtacagg aagcaggaag cagaagaaaa
    39901 aaaaaatatt tggggaattt cacattcccc agtctgtgaa ggaagcgaca aaaataggaa
    39961 agatcctaat actaggggct gacgtggtca attagcacaa gaactgctgt acacagtagt
    40021 ctacttactt cattcactca atcaacaatt tcttactgat ggagacagct gggtctctct
    40081 ctctctgcct ctgtctaagc agccaaaaag cagcaccagc agcacagcaa ctttggttag
    40141 acacctggga ggagcggcct tagtgccacg ctaggccgag cggggcgggc gaagaaagac
    40201 taggttccaa ccgacttgtg ccgcacccaa ccctcttctt ttctttcttt tccttccata
    40261 atggaattaa ggaatttctc ccctccctca tttaattatt ccataacacg gtggatacgt
    40321 tcccatggtc cagggcaagc caccaatatt tagcttcatt attgatctgg agtccgtgta
    40381 gcgtcatcgc ttgctttctc tctacgaatt ccaatccgct acagttgcct cctacgtcct
    40441 cgtatcttcc tgctttctct tcccggagct agtctatcta tctatctatc tacttatctc
    40501 gccatctgga tcggatttag tacgcagtcg taatccagct gcgcttgtta atgaattcca
    40561 cgagtgaaat aaaaaaaaca ataacagaat ataaggtctg aaaaaaaaaa aaaaaaaaca
    40621 aaacaaaaca aaacaaaaca aaagctaaat ctacactcgg acctacagag tagtagtatc
    40681 tactcagacc tcggaatatg aatatggagt aactttcgag ctgatcacgg gtcaagttgc
    40741 ttccctttca attttagcct ctgatgatcc cgttgaaatc tctgcaggta cggtgtagtt
    40801 tagttcgttc tatacatcag ctccctctta ccgcggaagg cttattgtgt cttccctcct
    40861 caaccccgaa ccgggtacgg agaagtacgg agggattagg tactgacagg catcgtctct
    40921 caatcatgac atgacactcg cgcaaacacc cctgcacctg cacctgcaga tgatttgaga
    40981 gaaataatag ctactacccc ggccgagtca cacaggtgtt tttgtgactt tcacccctga
    41041 aataaaggag cagagtaaaa attacaattt acacagatag actcttgctc ggatggtggg
    41101 ttctgatctg atctcatacc atcacacaag gtagtctatg tgactggtaa tgataaccac
    41161 gagcagagaa tcttgatgta tttggttcta gaaaagcttt caccgactag aaattcttgc
    41221 tgagtactcc ataagcatgc aataactaat cacccacagg acgaaagctg acttaattaa
    41281 ctgacggaac ggattccatt ccttccatcc attgcagcgg ggatgaagtc agagtccccg
    41341 agacggagtg actccgcact ctaactaact tactgtatga agacggacaa gaaagatgta
    41401 tccgctcaac aactctagat atcacttcga catatcactt atttatatat gaaacttggc
    41461 ttttgaatcg attatacaat actctgcaca tcccaattga ataaacaatt acataaacaa
    41521 ttaaatagta ttgattgagt gggattgacc agtctactca aaactgccat ggcgcgggat
    41581 cggcaaagcc cgtcattttc cgtctcggca caaacaaaat gggatggatg gtcgaggcct
    41641 agaactttgg gttttttttt ttttcatctt gggtcatttt tcgttatttt tgaacgggcg
    41701 tttcgttcca aggacggaat aacatcatct acttacttac tcgaggttgc agatttagga
    41761 tgagtggtct gatgtcatgg cggccctgtg tgtgcgaaat cgatcgaatc agatgatagt
    41821 gatttttctt ctagaaaaag ttggatggta ttcatcacat cccatttact gcgccacgat
    41881 tgattgatgc agtatcctgg ccatactcgg tcatcgtgta cggagtagat agtggatggc
    41941 atgactgata attagtatga ctgctctcaa tgttcactta aatcagtggc atagcccccc
    42001 tccccgaagc cagattctcc tacagtgtca gtctaggcag acattcattt tctctttctt
    42061 gttcaaggcc ctcatgctcg gtcatttgcg cccatcagtc cccatccaat gactcgtagg
    42121 aactttgtta gcgtggagac tctcgaacat gattcaagca agctagaagc caaacttcgt
    42181 tcactcttgc gatcgctgac gtcacaggac ccaacttagc ctgcgatgga aacctgaagc
    42241 cattactgta ctgcttctgg tatagcgaca aagtaaaaaa aaaaatatta tctacctcat
    42301 ccatttattt ccattacaga gaggaattta catacccccc gaaagaagaa caatattatg
    42361 gaactccttc cccccaagac ctataggaat cttaatttgg accctaaaaa tcaactttcc
    42421 aactatctaa ccaacatcca ttccccatct taatcccaat aataaaatga cgagtaactg
    42481 cagccttgaa ccgaggtaag ctagatggtt tgttctgttg tcgttgtttc atcatcagtc
    42541 ccaaaaacca gaacttcgac gatcaaactt accctaccct actgtatccc cccacccacc
    42601 accacccact cccactaacc ggaccaaagt tactactgac caattttagt acaagattag
    42661 tctggtagtt aagttaagct ctgaaacttg ccagcgatga gaggggggcg aaagtatata
    42721 ggcaaacacg tggggggggt gaagttctac ccaatccatg ccgaatattg attctatcaa
    42781 tactgccagg agttggaagt aactcttggt acttgacagg tattgtttca tgcttgaact
    42841 tagataatgt gttgtgttag cttatatggg ggaagagagg agttgtgtat taggtgatga
    42901 cagtcggctg ctagtcgctt attgggtagg gtgtatgagc tggtgagaga gggaggacta
    42961 ctactactac tactagagtt ggattgagaa ggaggtcttt agtattgaac gtatcaatat
    43021 actgcttctt ggtaagtcta aattgaattc atattgcagt tacggggtgg aattgacttt
    43081 tgttgcaatt gttgttgttt gtattgcacc atatctttat acactatata taagaaatga
    43141 ggaggtgata ttgggggata gatgtttcat ggatgtgtat gcgtgctggc aggtacttag
    43201 atacatacta atctactttg gctgatgtgg tttcgtttat gtacttcaga gacaaggtgc
    43261 atgtagtagc tatccaatta tctacttgaa aatcaagtgc tattgttctg gtggtatgat
    43321 tatagcagag atcataggag ttgcattatc attaaccatc aatatatata tcgtggcctg
    43381 ccgttcatcg tcatgataat atgatcatag tgtacatgtg ttgctcatct accgtccaac
    43441 gtacttcaac tccagcttcc gcaagggaat atacgataag ctagtaaaaa caaacgccag
    43501 ctcattggca atgtctcctc catcggtgcc aatcttgcgc gccagcgctc caacataata
    43561 cgtttcgtcc atgccgacaa tccagccggc cgcaccgcat aggaacgccg tgagaccggc
    43621 gtagccgacg ggcagtttcg acggcgtgtt ccaggcgtcg aggtcgtagt tggccaggtt
    43681 gccgttgcgg aagaagtagt gttcgcagaa caaaatgacg aaaaaggagg tgttccagta
    43741 acccaagagg gagaggaaat tatccaggac agtcagcagg tggtcccggc ctgcgatacc
    43801 aatgacaaga atgcaggcga acacgagtag tgtccaaata attcggggga tcttctggaa
    43861 gggtttggcg aataattgtg ccgaaaggga tccagcataa atggcaatgc agttcatacc
    43921 gactatattg tagtgttagt agcggttatg acgtgaggta agtgggtata cttactgcca
    43981 cacagcacca gcaagaccaa gaggaactta gcaaatttgc ggggatagat gatggtctgc
    44041 aagatctctc cagttccttg gtcataggca gcagcccatt ctgggtttcc gtccagggca
    44101 gatgcgatac acgcaccgag caacattccg atacaagtcg ggagtgaaat acccagggtg
    44161 gtgtagatga agaccttgac cttcgaggtg ttgaccgggt agtgtacata aaagtcagac
    44221 acgatcgagc accacgatgc actcgagcca tagataacgc tgatcaggct cagaacattt
    44281 ccggacttgg tcagcccgga cacggtaccg ggatctgaca ggctggcgtg gtgggccgat
    44341 tcaccgtaga cgatgatgaa gacgacaaag gaaaccatcc aaatgtattg ctcaatggtc
    44401 ataacagccc taagaccgaa gaagctgaaa cacagactaa cgcatgcaac aatgacgact
    44461 cccacgacca tggaaatgtg attgtccgaa acggcacgaa gagcttgacc accagtaata
    44521 cagctgacag aggcccagcc cagctgttcg acgacattca gcgccgcgat gatggaggag
    44581 gggtagaagc caaaggagta tctagagatg gcgacttgac gaaggccagt gccagggccc
    44641 atcgtggcac accaacccta gtgaaccgac atgtaagcct ttagacagac cataagatga
    44701 gtgcgccgca ttgcgtcgca gcgaaagata ggtagagaaa gtggtatgcg aaccgtgaga
    44761 gcagcgccca gaaacgtcgc gcaaatcata atggcgatcg tctgccctag ggtcaagcca
    44821 aactccttcc ccataaagcc cgtactgaaa caactgaggt tcatggtggc cgatgcccag
    44881 atgaaggcca tggccaaggt gttaggcggt ttgcgctctt cgggcaggac tcgatcgaga
    44941 ctgtgggact caacgcccat tttccgatcc aacagctctt catagtagcg gatgcgggcg
    45001 aagaaaccgc taggtttaac cagggcgtgt tcctccaccg aagcggtggc ctgcttcggt
    45061 tcgatggggt tgccatcctc aagggttttg aaatccat
//
